5 results on '"Duquaire, Paul"'
Search Results
2. Multicentric evaluation of BioFire FilmArray Pneumonia Panel for rapid bacteriological documentation of pneumonia
- Author
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Gastli, Nabil, primary, Loubinoux, Julien, additional, Daragon, Matthieu, additional, Lavigne, Jean-Philippe, additional, Saint-Sardos, Pierre, additional, Pailhoriès, Hélène, additional, Lemarié, Carole, additional, Benmansour, Hanaa, additional, d’Humières, Camille, additional, Broutin, Lauranne, additional, Dauwalder, Olivier, additional, Levy, Michael, additional, Auger, Gabriel, additional, Kernéis, Solen, additional, Cattoir, Vincent, additional, Alviset, Sophie, additional, Armand-Lefèvre, Laurence, additional, Baldeyrou, Marion, additional, Becker, Agathe, additional, Boibieux, André, additional, Bonacorsi, Stéphane, additional, Burucoa, Christophe, additional, Cambau, Emmanuelle, additional, Casalegno, Jean-Sébastien, additional, Cointe, Aurélie, additional, Cremniter, Julie, additional, Destras, Grégory, additional, Duquaire, Paul, additional, Geslain, Guillaume, additional, Gustave, Claude-Alexandre, additional, Jacquier, Hervé, additional, Kouatchet, Achille, additional, Lecorche, Emmanuel, additional, Lejeune, Manon, additional, Lina, Bruno, additional, Mahieu, Rafaël, additional, Maamar, Adel, additional, Michaud, Anthony, additional, Monnard, Céline, additional, Montravers, Philippe, additional, Neuwirth, Catherine, additional, Péan de Ponfilly, Gauthier, additional, Pichon, Maxime, additional, Plouzeau, Chloé, additional, Poyart, Claire, additional, Quenot, Jean-Pierre, additional, Rzepecki, Vincent, additional, Stéphan, Robin, additional, Timsit, Jean-François, additional, Tran-Dinh, Alexy, additional, Vandenesch, François, additional, and Vigier, Emmanuelle, additional
- Published
- 2021
- Full Text
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3. Additional file 1 of Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia
- Author
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Monard, Céline, Pehlivan, Jonathan, Auger, Gabriel, Alviset, Sophie, Dinh, Alexy Tran, Duquaire, Paul, Gastli, Nabil, D’Humières, Camille, Maamar, Adel, Boibieux, André, Baldeyrou, Marion, Loubinoux, Julien, Dauwalder, Olivier, Cattoir, Vincent, Armand-Lefèvre, Laurence, and Kernéis, Solen
- Abstract
Additional file 1: Supplementary table 1. Microbiological documentation depending on the sample type (n=159). Supplementary table 2. Impact of the rm-PCR results on antibiotic prescription, according to the multidisciplinary committee and regarding sample type (n=159). Supplementary Table 3. Description of inadequate antibiotic regimen.
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- 2020
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4. Eléments pour une philosophie de la création
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Duquaire, Paul-Victor, Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Université de Rouen Normandie, Jean-Pierre Cléro, and DUQUAIRE, Paul-Victor
- Subjects
openness ,philosophy ,Creation ,Thomas d’Aquin ,[SHS.PHIL]Humanities and Social Sciences/Philosophy ,Création ,Deleuze ,Heidegger ,Husserl ,horizon ,institution ,Kant ,[SHS.PHIL] Humanities and Social Sciences/Philosophy ,Thomas Aquinas ,theology ,aesthetics ,théologie ,ouverture ,philosophie ,Lacan ,Anzieu ,transcendance ,transcendence ,esthétique - Abstract
This research deals with the creation at large in order to propose if not a philosophy of creation, at least an admissible interpretative hypothesis. It seeks to explore some elements of theology, philosophy and aesthetics according to a periodic method. The first part clarifies the transcendent conception of creation by focusing on Thomas Aquinas. It shows that, from Genesis until Descartes and Leibniz creation is thought through the divine perfection as radical otherness, both in terms of creatio ex nihilo than of continuous creation. The second part implements the critical conception of creation through the course of Kant. Noumenal Kant relegation and liquidation of creatio ex nihilo by Fichte begin the reversal of the divine agent in favor of the subject, which obtains full powers with Nietzsche. The third part forms the hypothesis of a constitutive conception of creation by building on the symbolic institution that takes place in Lacan and in Anzieu’s creative process. From Bergson to Deleuze via Heidegger's thought of Schöpfung, we emphasize openness to transcendence, inherent to the creation, leading to distinguish it from neighboring concepts: evolution, invention, art and creativity. The research leads to the assumption of pentalogy composed of distinct and interrelated nodal points: obstacle, repetition, jouissance, secretion and burial. The confrontation of this hypothesis to the philosophies of Kant, Husserl, Heidegger, Lacan and Deleuze, provides the basis for a new constitutive approach to creation., Cette recherche traite de la création au sens large en vue d’en proposer sinon une philosophie du moins une hypothèse interprétative recevable. Elle s’attache à étudier des éléments de théologie, de philosophie et d’esthétique suivant une méthode périodique. La première partie tire au clair la conception transcendante de la création en se focalisant sur Thomas d’Aquin. Elle montre que, depuis la Genèse et jusqu’à Descartes et Leibniz la création est pensée depuis la perfection divine comme altérité radicale, tant en ce qui concerne la creatio ex nihilo que la création continuée. La seconde partie met en œuvre la conception critique de la création à travers le parcours de Kant. La relégation nouménale chez Kant et la liquidation de la creatio ex nihilo chez Fichte amorcent le renversement de l’agent divin au profit du sujet, qui s’octroie les pleins pouvoirs avec Nietzsche. La troisième partie forme l’hypothèse d’une conception constitutive de la création en prenant appui sur l’institution symbolique qui a lieu chez Lacan et dans le processus créateur d’ Anzieu. De Bergson à Deleuze via la pensée heideggerienne de la Schöpfung, on insiste sur l’ouverture à la transcendance inhérente à la création, qui conduit à la distinguer de concepts limitrophes : évolution, invention, technique et créativité. La recherche aboutit à l’hypothèse d’une pentalogie composée de points nodaux distincts et indissociables : obstacle, répétition, jouissance, sécrétion et sépulture. La confrontation de cette hypothèse aux philosophies de Kant, Husserl, Heidegger, Deleuze et Lacan, apporte un fondement à une nouvelle approche constitutive de la création.
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- 2015
5. Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia.
- Author
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Monard, Céline, Pehlivan, Jonathan, Auger, Gabriel, Alviset, Sophie, Tran Dinh, Alexy, Duquaire, Paul, Gastli, Nabil, d'Humières, Camille, Maamar, Adel, Boibieux, André, Baldeyrou, Marion, Loubinoux, Julien, Dauwalder, Olivier, Cattoir, Vincent, Armand-Lefèvre, Laurence, Kernéis, Solen, the ADAPT study group, Becker, Agathe, Charpentier, Julien, and Textoris, Julien
- Subjects
PNEUMONIA ,RESEARCH ,TIME ,RESEARCH methodology ,ANTI-infective agents ,RETROSPECTIVE studies ,MEDICAL cooperation ,EVALUATION research ,COMPARATIVE studies ,COMMUNITY-acquired infections ,POLYMERASE chain reaction - Abstract
Background: Improving timeliness of pathogen identification is crucial to allow early adaptation of antibiotic therapy and improve prognosis in patients with pneumonia. We evaluated the relevance of a new syndromic rapid multiplex PCR test (rm-PCR) on respiratory samples to guide empirical antimicrobial therapy in adult patients with community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP), and ventilator-acquired pneumonia (VAP).Methods: This retrospective multicenter study was conducted in four French university hospitals. Respiratory samples were obtained from patients with clinical and radiological signs of pneumonia and simultaneously tested using conventional microbiological methods and the rm-PCR. A committee composed of an intensivist, a microbiologist, and an infectious diseases specialist retrospectively assessed all medical files and agreed on the most appropriate antimicrobial therapy for each pneumonia episode, according to the results of rm-PCR and blinded to the culture results. The rm-PCR-guided antimicrobial regimen was compared to the empirical treatment routinely administered to the patient in standard care.Results: We included 159 pneumonia episodes. Most patients were hospitalized in intensive care units (n = 129, 81%), and episodes were HAP (n = 68, 43%), CAP (n = 54, 34%), and VAP (n = 37, 23%). Conventional culture isolated ≥ 1 microorganism(s) at significant level in 95 (60%) patients. The syndromic rm-PCR detected at least one bacteria in 132 (83%) episodes. Based on the results of the rm-PCR, the multidisciplinary committee proposed a modification of the empirical therapy in 123 (77%) pneumonia episodes. The modification was a de-escalation in 63 (40%), an escalation in 35 (22%), and undetermined in 25 (16%) patients. In microbiologically documented episodes (n = 95), the rm-PCR increased appropriateness of the empirical therapy to 83 (87%), as compared to 73 (77%) in routine care.Conclusions: Use of a syndromic rm-PCR test has the potential to reduce unnecessary antimicrobial exposure and increase the appropriateness of empirical antibiotic therapy in adult patients with pneumonia. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
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