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363 results on '"Dupuy, Adam J."'

1. Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

Author

Vaishnavi, Aria, Juan, Joseph, Jacob, Maebh, Stehn, Christopher, Gardner, Eric E, Scherzer, Michael T, Schuman, Sophia, van Veen, J Edward, Murphy, Brandon, Hackett, Christopher S, Dupuy, Adam J, Chmura, Steve A, van der Weyden, Louise, Newberg, Justin Y, Liu, Annie, Mann, Karen, Rust, Alistair G, Weiss, William A, Kinsey, Conan G, Adams, David J, Grossmann, Allie, Mann, Michael B, and McMahon, Martin

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Lung, Rare Diseases, Genetics, Lung Cancer, Cancer, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Animals, Humans, Mice, Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Cell Proliferation, Lung Neoplasms, Mutagenesis, Proto-Oncogene Proteins B-raf, RNA-Binding Proteins, Trans-Activators, Wnt Signaling Pathway, Carcinogenesis, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis
Abstract

Mutationally activated BRAF is detected in approximately 7% of human lung adenocarcinomas, with BRAFT1799A serving as a predictive biomarker for treatment of patients with FDA-approved inhibitors of BRAFV600E oncoprotein signaling. In genetically engineered mouse (GEM) models, expression of BRAFV600E in the lung epithelium initiates growth of benign lung tumors that, without additional genetic alterations, rarely progress to malignant lung adenocarcinoma. To identify genes that cooperate with BRAFV600E for malignant progression, we used Sleeping Beauty-mediated transposon mutagenesis, which dramatically accelerated the emergence of lethal lung cancers. Among the genes identified was Rbms3, which encodes an RNA-binding protein previously implicated as a putative tumor suppressor. Silencing of RBMS3 via CRISPR/Cas9 gene editing promoted growth of BRAFV600E lung organoids and promoted development of malignant lung cancers with a distinct micropapillary architecture in BRAFV600E and EGFRL858R GEM models. BRAFV600E/RBMS3Null lung tumors displayed elevated expression of Ctnnb1, Ccnd1, Axin2, Lgr5, and c-Myc mRNAs, suggesting that RBMS3 silencing elevates signaling through the WNT/β-catenin signaling axis. Although RBMS3 silencing rendered BRAFV600E-driven lung tumors resistant to the effects of dabrafenib plus trametinib, the tumors were sensitive to inhibition of porcupine, an acyltransferase of WNT ligands necessary for their secretion. Analysis of The Cancer Genome Atlas patient samples revealed that chromosome 3p24, which encompasses RBMS3, is frequently lost in non-small cell lung cancer and correlates with poor prognosis. Collectively, these data reveal the role of RBMS3 as a lung cancer suppressor and suggest that RBMS3 silencing may contribute to malignant NSCLC progression.SignificanceLoss of RBMS3 cooperates with BRAFV600E to induce lung tumorigenesis, providing a deeper understanding of the molecular mechanisms underlying mutant BRAF-driven lung cancer and potential strategies to more effectively target this disease.

Published
2022

5. A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis

Author

Ziyad, Safiyyah, Riordan, Jesse D, Cavanaugh, Ann M, Su, Trent, Hernandez, Gloria E, Hilfenhaus, Georg, Morselli, Marco, Huynh, Kristine, Wang, Kevin, Chen, Jau-Nian, Dupuy, Adam J, and Iruela-Arispe, M Luisa

Subjects
Biochemistry and Cell Biology, Biological Sciences, Stem Cell Research, Cancer, Rare Diseases, Hematology, Genetics, 2.1 Biological and endogenous factors, Aetiology, Animals, Cell Differentiation, Erythropoiesis, Hemangioblasts, Humans, Leukemia, Mice, Mice, Inbred C57BL, Mice, Transgenic, Minor Histocompatibility Antigens, Mutagenesis, Myelopoiesis, Phosphotransferases (Alcohol Group Acceptor), Zebrafish, Akt, Erk, PI4KAP2, Pi4ka, erythropoiesis, hematopoiesis, hemogenic endothelium, leukemia, lipid kinase, myelopoiesis, Medical Physiology, Biological sciences
Abstract

Given its role as the source of definitive hematopoietic cells, we sought to determine whether mutations initiated in the hemogenic endothelium would yield hematopoietic abnormalities or malignancies. Here, we find that endothelium-specific transposon mutagenesis in mice promotes hematopoietic pathologies that are both myeloid and lymphoid in nature. Frequently mutated genes included previously recognized cancer drivers and additional candidates, such as Pi4ka, a lipid kinase whose mutation was found to promote myeloid and erythroid dysfunction. Subsequent validation experiments showed that targeted inactivation of the Pi4ka catalytic domain or reduction in mRNA expression inhibited myeloid and erythroid cell differentiation in vitro and promoted anemia in vivo through a mechanism involving deregulation of AKT, MAPK, SRC, and JAK-STAT signaling. Finally, we provide evidence linking PI4KAP2, previously considered a pseudogene, to human myeloid and erythroid leukemia.

Published
2018

7. Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer

Author

Schachter, Nathan F., Adams, Jessica R., Skowron, Patryk, Kozma, Katelyn. J., Lee, Christian A., Raghuram, Nandini, Yang, Joanna, Loch, Amanda J., Wang, Wei, Kucharczuk, Aaron, Wright, Katherine L., Quintana, Rita M., An, Yeji, Dotzko, Daniel, Gorman, Jennifer L., Wojtal, Daria, Shah, Juhi S., Leon-Gomez, Paul, Pellecchia, Giovanna, Dupuy, Adam J., Perou, Charles M., Ben-Porath, Ittai, Karni, Rotem, Zacksenhaus, Eldad, Woodgett, Jim R., Done, Susan J., Garzia, Livia, Sorana Morrissy, A., Reimand, Jüri, Taylor, Michael D., and Egan, Sean E.

Published
2021
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9. Clonal selection drives genetic divergence of metastatic medulloblastoma.

Author

Wu, Xiaochong, Northcott, Paul A, Dubuc, Adrian, Dupuy, Adam J, Shih, David JH, Witt, Hendrik, Croul, Sidney, Bouffet, Eric, Fults, Daniel W, Eberhart, Charles G, Garzia, Livia, Van Meter, Timothy, Zagzag, David, Jabado, Nada, Schwartzentruber, Jeremy, Majewski, Jacek, Scheetz, Todd E, Pfister, Stefan M, Korshunov, Andrey, Li, Xiao-Nan, Scherer, Stephen W, Cho, Yoon-Jae, Akagi, Keiko, MacDonald, Tobey J, Koster, Jan, McCabe, Martin G, Sarver, Aaron L, Collins, V Peter, Weiss, William A, Largaespada, David A, Collier, Lara S, and Taylor, Michael D

Subjects
Animals, Humans, Mice, Medulloblastoma, Neoplasm Metastasis, Li-Fraumeni Syndrome, Disease Models, Animal, DNA Transposable Elements, Survival Rate, Mutagenesis, Insertional, DNA Methylation, CpG Islands, Germ-Line Mutation, Genes, p53, Clonal Evolution, Disease Models, Animal, Genes, p53, Mutagenesis, Insertional, General Science & Technology
Abstract

Medulloblastoma, the most common malignant paediatric brain tumour, arises in the cerebellum and disseminates through the cerebrospinal fluid in the leptomeningeal space to coat the brain and spinal cord. Dissemination, a marker of poor prognosis, is found in up to 40% of children at diagnosis and in most children at the time of recurrence. Affected children therefore are treated with radiation to the entire developing brain and spinal cord, followed by high-dose chemotherapy, with the ensuing deleterious effects on the developing nervous system. The mechanisms of dissemination through the cerebrospinal fluid are poorly studied, and medulloblastoma metastases have been assumed to be biologically similar to the primary tumour. Here we show that in both mouse and human medulloblastoma, the metastases from an individual are extremely similar to each other but are divergent from the matched primary tumour. Clonal genetic events in the metastases can be demonstrated in a restricted subclone of the primary tumour, suggesting that only rare cells within the primary tumour have the ability to metastasize. Failure to account for the bicompartmental nature of metastatic medulloblastoma could be a major barrier to the development of effective targeted therapies.

Published
2012

12. Mammalian Germ-Line Transgenesis by Transposition

Author

Dupuy, Adam J., Clark, Karl, Carlson, Corey M., Fritz, Sabine, Davidson, Ann E., Markley, Karra M., Finley, Ken, Fletcher, Colin F., Ekker, Stephen C., Hackett, Perry B., Horn, Sandra, and Largaespada, David A.

Published
2002

22. Supplementary Data from Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

Author

Vaishnavi, Aria, primary, Juan, Joseph, primary, Jacob, Maebh, primary, Stehn, Christopher, primary, Gardner, Eric E., primary, Scherzer, Michael T., primary, Schuman, Sophia, primary, Van Veen, J. Edward, primary, Murphy, Brandon, primary, Hackett, Christopher S., primary, Dupuy, Adam J., primary, Chmura, Steven A., primary, van der Weyden, Louise, primary, Newberg, Justin Y., primary, Liu, Annie, primary, Mann, Karen, primary, Rust, Alistair G., primary, Weiss, William A., primary, Kinsey, Conan G., primary, Adams, David J., primary, Grossmann, Allie, primary, Mann, Michael B., primary, and McMahon, Martin, primary

Published
2023
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23. Supplementary Methods and References from A Transposon-based Analysis Reveals RASA1 Is Involved in Triple-Negative Breast Cancer

Author

Suárez-Cabrera, Cristian, primary, Quintana, Rita M., primary, Bravo, Ana, primary, Casanova, M. Llanos, primary, Page, Angustias, primary, Alameda, Josefa P., primary, Paramio, Jesús M., primary, Maroto, Alicia, primary, Salamanca, Javier, primary, Dupuy, Adam J., primary, Ramírez, Angel, primary, and Navarro, Manuel, primary

Published
2023
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24. Supplementary Tables S7-18 from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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25. Supplementary Tables S1-6 from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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26. Supplementary Tables S1-S7 from A Transposon-based Analysis Reveals RASA1 Is Involved in Triple-Negative Breast Cancer

Author

Suárez-Cabrera, Cristian, primary, Quintana, Rita M., primary, Bravo, Ana, primary, Casanova, M. Llanos, primary, Page, Angustias, primary, Alameda, Josefa P., primary, Paramio, Jesús M., primary, Maroto, Alicia, primary, Salamanca, Javier, primary, Dupuy, Adam J., primary, Ramírez, Angel, primary, and Navarro, Manuel, primary

Published
2023
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27. Data from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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28. Data from Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma

Author

Feddersen, Charlotte R., primary, Schillo, Jacob L., primary, Varzavand, Afshin, primary, Vaughn, Hayley R., primary, Wadsworth, Lexy S., primary, Voigt, Andrew P., primary, Zhu, Eliot Y., primary, Jennings, Brooke M., primary, Mullen, Sarah A., primary, Bobera, Jeremy, primary, Riordan, Jesse D., primary, Stipp, Christopher S., primary, and Dupuy, Adam J., primary

Published
2023
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29. Supplemental Tables from Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma

Author

Feddersen, Charlotte R., primary, Schillo, Jacob L., primary, Varzavand, Afshin, primary, Vaughn, Hayley R., primary, Wadsworth, Lexy S., primary, Voigt, Andrew P., primary, Zhu, Eliot Y., primary, Jennings, Brooke M., primary, Mullen, Sarah A., primary, Bobera, Jeremy, primary, Riordan, Jesse D., primary, Stipp, Christopher S., primary, and Dupuy, Adam J., primary

Published
2023
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30. Supplementary Figures S1 from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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31. Supplementary Figures S2-4 from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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33. Data from Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

Author

Vaishnavi, Aria, primary, Juan, Joseph, primary, Jacob, Maebh, primary, Stehn, Christopher, primary, Gardner, Eric E., primary, Scherzer, Michael T., primary, Schuman, Sophia, primary, Van Veen, J. Edward, primary, Murphy, Brandon, primary, Hackett, Christopher S., primary, Dupuy, Adam J., primary, Chmura, Steven A., primary, van der Weyden, Louise, primary, Newberg, Justin Y., primary, Liu, Annie, primary, Mann, Karen, primary, Rust, Alistair G., primary, Weiss, William A., primary, Kinsey, Conan G., primary, Adams, David J., primary, Grossmann, Allie, primary, Mann, Michael B., primary, and McMahon, Martin, primary

Published
2023
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34. Supplementary Figures S11-13 from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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35. Supplementary Figures S5-7 from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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36. Supplementary Figures 9-10 from Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors

Author

Tschida, Barbara R., primary, Temiz, Nuri A., primary, Kuka, Timothy P., primary, Lee, Lindsey A., primary, Riordan, Jesse D., primary, Tierrablanca, Carlos A., primary, Hullsiek, Robert, primary, Wagner, Sandra, primary, Hudson, Wendy A., primary, Linden, Michael A., primary, Amin, Khalid, primary, Beckmann, Pauline J., primary, Heuer, Rachel A., primary, Sarver, Aaron L., primary, Yang, Ju Dong, primary, Roberts, Lewis R., primary, Nadeau, Joseph H., primary, Dupuy, Adam J., primary, Keng, Vincent W., primary, and Largaespada, David A., primary

Published
2023
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37. Supplementary Data from Src-Dependent DBL Family Members Drive Resistance to Vemurafenib in Human Melanoma

Author

Feddersen, Charlotte R., primary, Schillo, Jacob L., primary, Varzavand, Afshin, primary, Vaughn, Hayley R., primary, Wadsworth, Lexy S., primary, Voigt, Andrew P., primary, Zhu, Eliot Y., primary, Jennings, Brooke M., primary, Mullen, Sarah A., primary, Bobera, Jeremy, primary, Riordan, Jesse D., primary, Stipp, Christopher S., primary, and Dupuy, Adam J., primary

Published
2023
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38. Data from Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Author

Collier, Lara S., primary, Adams, David J., primary, Hackett, Christopher S., primary, Bendzick, Laura E., primary, Akagi, Keiko, primary, Davies, Michael N., primary, Diers, Miechaleen D., primary, Rodriguez, Fausto J., primary, Bender, Aaron M., primary, Tieu, Christina, primary, Matise, Ilze, primary, Dupuy, Adam J., primary, Copeland, Neal G., primary, Jenkins, Nancy A., primary, Hodgson, J. Graeme, primary, Weiss, William A., primary, Jenkins, Robert B., primary, and Largaespada, David A., primary

Published
2023
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42. Supplementary Table 3 from Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Author

Collier, Lara S., primary, Adams, David J., primary, Hackett, Christopher S., primary, Bendzick, Laura E., primary, Akagi, Keiko, primary, Davies, Michael N., primary, Diers, Miechaleen D., primary, Rodriguez, Fausto J., primary, Bender, Aaron M., primary, Tieu, Christina, primary, Matise, Ilze, primary, Dupuy, Adam J., primary, Copeland, Neal G., primary, Jenkins, Nancy A., primary, Hodgson, J. Graeme, primary, Weiss, William A., primary, Jenkins, Robert B., primary, and Largaespada, David A., primary

Published
2023
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43. Supplementary Figure 2 from Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Author

Collier, Lara S., primary, Adams, David J., primary, Hackett, Christopher S., primary, Bendzick, Laura E., primary, Akagi, Keiko, primary, Davies, Michael N., primary, Diers, Miechaleen D., primary, Rodriguez, Fausto J., primary, Bender, Aaron M., primary, Tieu, Christina, primary, Matise, Ilze, primary, Dupuy, Adam J., primary, Copeland, Neal G., primary, Jenkins, Nancy A., primary, Hodgson, J. Graeme, primary, Weiss, William A., primary, Jenkins, Robert B., primary, and Largaespada, David A., primary

Published
2023
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44. Supplementary Table 2 from Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Author

Collier, Lara S., primary, Adams, David J., primary, Hackett, Christopher S., primary, Bendzick, Laura E., primary, Akagi, Keiko, primary, Davies, Michael N., primary, Diers, Miechaleen D., primary, Rodriguez, Fausto J., primary, Bender, Aaron M., primary, Tieu, Christina, primary, Matise, Ilze, primary, Dupuy, Adam J., primary, Copeland, Neal G., primary, Jenkins, Nancy A., primary, Hodgson, J. Graeme, primary, Weiss, William A., primary, Jenkins, Robert B., primary, and Largaespada, David A., primary

Published
2023
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47. Supplementary Table 1 from Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Author

Collier, Lara S., primary, Adams, David J., primary, Hackett, Christopher S., primary, Bendzick, Laura E., primary, Akagi, Keiko, primary, Davies, Michael N., primary, Diers, Miechaleen D., primary, Rodriguez, Fausto J., primary, Bender, Aaron M., primary, Tieu, Christina, primary, Matise, Ilze, primary, Dupuy, Adam J., primary, Copeland, Neal G., primary, Jenkins, Nancy A., primary, Hodgson, J. Graeme, primary, Weiss, William A., primary, Jenkins, Robert B., primary, and Largaespada, David A., primary

Published
2023
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49. Supplementary Figure 1 from Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Author

Collier, Lara S., primary, Adams, David J., primary, Hackett, Christopher S., primary, Bendzick, Laura E., primary, Akagi, Keiko, primary, Davies, Michael N., primary, Diers, Miechaleen D., primary, Rodriguez, Fausto J., primary, Bender, Aaron M., primary, Tieu, Christina, primary, Matise, Ilze, primary, Dupuy, Adam J., primary, Copeland, Neal G., primary, Jenkins, Nancy A., primary, Hodgson, J. Graeme, primary, Weiss, William A., primary, Jenkins, Robert B., primary, and Largaespada, David A., primary

Published
2023
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50. Supplementary Table 4 from Whole-Body Sleeping Beauty Mutagenesis Can Cause Penetrant Leukemia/Lymphoma and Rare High-Grade Glioma without Associated Embryonic Lethality

Author

Collier, Lara S., primary, Adams, David J., primary, Hackett, Christopher S., primary, Bendzick, Laura E., primary, Akagi, Keiko, primary, Davies, Michael N., primary, Diers, Miechaleen D., primary, Rodriguez, Fausto J., primary, Bender, Aaron M., primary, Tieu, Christina, primary, Matise, Ilze, primary, Dupuy, Adam J., primary, Copeland, Neal G., primary, Jenkins, Nancy A., primary, Hodgson, J. Graeme, primary, Weiss, William A., primary, Jenkins, Robert B., primary, and Largaespada, David A., primary

Published
2023
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