Search

Your search keyword '"Dunst, J."' showing total 1,066 results
Start Over Author "Dunst, J."
1,066 results on '"Dunst, J."'

3. Integration of radiation oncology teaching in medical studies by German medical faculties due to the new licensing regulations: An overview and recommendations of the consortium academic radiation oncology of the German Society for Radiation Oncology (DEGRO)

Author

Dapper, H., Belka, C., Bock, F., Budach, V., Budach, W., Christiansen, H., Debus, J., Distel, L., Dunst, J., Eckert, F., Eich, H., Eicheler, W., Engenhart-Cabillic, R., Fietkau, R., Fleischmann, D. F., Frerker, B., Giordano, F. A., Grosu, A. L., Herfarth, K., Hildebrandt, G., Kaul, D., Kölbl, O., Krause, M., Krug, D., Martin, D., Matuschek, C., Medenwald, D., Nicolay, N. H., Niewald, M., Oertel, M., Petersen, C., Pohl, F., Raabe, A., Rödel, C., Rübe, C., Schmalz, C., Schmeel, L. C., Steinmann, D., Stüben, G., Thamm, R., Vordermark, D., Vorwerk, H., Wiegel, T., Zips, D., and Combs, S. E.

Published
2022
Full Text
View/download PDF

4. Imaging-based target volume reduction in chemoradiotherapy for locally advanced non-small-cell lung cancer (PET-Plan): a multicentre, open-label, randomised, controlled trial

Author

Grosu, A L, Weber, W, Meyer, P, Hoffmanns, H, Nestle, U, Aurisch, R, Schäfer, W, Hehr, T, Eschmann, S M, Dornoff, W, Siekmeyer, B, Trampert, L, Gademann, G, Brunner, T, Amthauer, A, Ricke, J, Pech, M, Rübe, C, Kirsch, C M, Ezzidin, S, Schmidberger, H, Schreckenberger, M, Bamberg, M, Zips, D, Bares, R, La Fougere, C, Budach, V, Brenner, W, Beck, M, Freiherr von Gumppenberg, R, Aebersold, D, Krause, T, Feldmann, H J, Hertel, A, Stüben, G, Sciuk, J, Annweiler, H, Holl, G, Oehler, W, Schlöcker, I, Baum, R, Kimmig, B, Dunst, J, Henze, E, Lützen, U, Schwaiger, M, Strehle, K, Alberti, W, Piroth, M, Tosch, M, Pötter, R, Widder, J, Herold, C, Freund, U, Momm, F, Sautter-Bihl, M L, Tatsch, K, Hildebrandt, G, Krause, B, Nestle, Ursula, Schimek-Jasch, Tanja, Kremp, Stephanie, Schaefer-Schuler, Andrea, Mix, Michael, Küsters, Andreas, Tosch, Marco, Hehr, Thomas, Eschmann, Susanne Martina, Bultel, Yves-Pierre, Hass, Peter, Fleckenstein, Jochen, Thieme, Alexander, Stockinger, Marcus, Dieckmann, Karin, Miederer, Matthias, Holl, Gabriele, Rischke, H Christian, Gkika, Eleni, Adebahr, Sonja, König, Jochem, and Grosu, Anca-Ligia

Published
2020
Full Text
View/download PDF

5. A Phase I Study of the DNA-PK Inhibitor Peposertib in Combination with Radiotherapy with or without Cisplatin in Patients with Advanced Head and Neck Tumors

Author

Samuels, M., Falkenius, J., Bar-Ad, V., Dunst, J., Triest, B., Yachnin, J., Rodriguez-Gutierrez, A., Kuipers, M., You, X., Sarholz, B., Locatelli, G., Becker, A., (0000-0001-9550-9050) Troost, E. G. C., Samuels, M., Falkenius, J., Bar-Ad, V., Dunst, J., Triest, B., Yachnin, J., Rodriguez-Gutierrez, A., Kuipers, M., You, X., Sarholz, B., Locatelli, G., Becker, A., and (0000-0001-9550-9050) Troost, E. G. C.

Abstract

Purpose: DNA-dependent protein kinase (DNA-PK) plays a key role in the repair of DNA double strand breaks via nonho- mologous end joining. Inhibition of DNA-PK can enhance the effect of DNA double strand break inducing anticancer thera- pies. Peposertib (formerly “M3814”) is an orally administered, potent, and selective small molecule DNA-PK inhibitor that has demonstrated radiosensitizing and antitumor activity in xenograft models and was well-tolerated in monotherapy. This phase 1 trial (National Clinical Trial 02516813) investigated the maximum tolerated dose, recommended phase 2 dose (RP2D), safety, and tolerability of peposertib in combination with palliative radiation therapy (RT) in patients with thoracic or head and neck tumors (arm A) and of peposertib in combination with cisplatin and curative-intent RT in patients with squamous cell carcinoma of the head and neck (arm B). Methods and Materials: Patients received peposertib once daily in ascending dose cohorts as a tablet or capsule in combina- tion with palliative RT (arm A) or in combination with intensity modulated curative-intent RT and cisplatin (arm B). Results: The most frequently observed treatment-emergent adverse events were radiation skin injury, fatigue, and nausea in arm A (n = 34) and stomatitis, nausea, radiation skin injury, and dysgeusia in arm B (n = 11). Based on evaluations of dose- limiting toxicities, tolerability, and pharmacokinetic data, RP2D for arm A was declared as 200 mg peposertib tablet once daily in combination with RT. In arm B (n = 11), 50 mg peposertib was declared tolerable in combination with curative-intent RT and cisplatin. However, enrollment was discontinued because of insufficient exposure at that dose, and the RP2D was not for- mally declared. Conclusions: Peposertib in combination with palliative RT was well-tolerated up to doses of 200 mg once daily as tablet with each RT fraction. When combined with RT and cisplatin, a tolerable peposertib dose yielded insuffic

Published
2024

7. Reproducible target transfer from electroanatomic mapping to radiotherapy planning systems for cardiac radioablation - cross-validation for the RAVENTA trial

Author

Hohmann, S, primary, Xie, J, additional, Grehn, M, additional, Karfoul, N, additional, Mehrhof, F, additional, Merten, R, additional, Rudic, B, additional, Krug, D, additional, Lyan, E, additional, Duncker, D, additional, Dunst, J, additional, Tilz, R, additional, Schweikard, A, additional, Blanck, O, additional, and Boda-Heggemann, J, additional

Published
2023
Full Text
View/download PDF

8. Stereotactic Arrhythmia Radioablation (STAR) for refractory ventricular tachycardia (VT) - A preliminary report from the German multicenter RAVENTA study

Author

Krug, D, primary, Hohmann, S, additional, Boda-Heggemann, J, additional, Mehrhof, F, additional, Grehn, M, additional, Lyan, E, additional, Merten, R, additional, Rudic, B, additional, Boldt, L H, additional, Kirstein, B, additional, Rades, D, additional, Bonnemeier, H, additional, Dunst, J, additional, Tilz, R, additional, and Blanck, O, additional

Published
2023
Full Text
View/download PDF

13. Harnblasenkarzinom

Author

Schöffski, P., Dunst, J., Höltl, W., Schmoll, H. -J., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
2006
Full Text
View/download PDF

14. Mammakarzinom der Frau

Author

Possinger, K., Schmid, P., Schmoll, H. -J., Höffken, K., Kreienberg, R., Dunst, J., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
2006
Full Text
View/download PDF

15. Analkarzinom

Author

Roelofsen, F., Schmoll, H. -J., Dunst, J., Schlag, P. M., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
2006
Full Text
View/download PDF

18. Radiosensitizer

Author

Rhomberg, W., Dunst, J., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
2006
Full Text
View/download PDF

20. EUSOM: Phase 2 Trial of Avasopasem Manganese (GC4419) for Oral Mucositis in Patients Receiving Chemoradiotherapy for Locally Advanced, Nonmetastatic Head and Neck Cancer

Author

Giralt, J., primary, Bunea, A., additional, Holečková, P., additional, Arias de la Vega, F., additional, Rutkowski, T., additional, Hervas, A., additional, Dunst, J., additional, Filarska, D., additional, Fernandez, J. Cacicedo, additional, Holmlund, J., additional, and Lybaert, W., additional

Published
2022
Full Text
View/download PDF

21. A step towards routine for stereotactic radioablation in refractory ventricular tachycardia – interim analysis on short term safety of the first prospective, multi-centre, multi-platform study RAVENTA

Author

Zaman, A, primary, Krug, D, additional, Eidinger, L, additional, Boda-Heggemann, J, additional, Rudic, B, additional, Mehrhof, F, additional, Boldt, L H, additional, Fleckenstein, J, additional, Kluge, A, additional, Siebert, F A, additional, Schweikard, A, additional, Vontlein, R, additional, Dunst, J, additional, Bonnemeier, H, additional, and Blanck, O, additional

Published
2022
Full Text
View/download PDF

23. Mammakarzinom

Author

Volm, T., Wedding, U., Dunst, J., Kreienberg, R., Höffken, K., Höffken, Klaus, editor, Wedding, Ulrich, editor, and Kolb, Gerald, editor

Published
2002
Full Text
View/download PDF

25. Harnblasenkarzinom

Author

Schöffski, P., Dunst, J., Herr, H. W., Höltl, H., Schmoll, H.-J., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
1999
Full Text
View/download PDF

26. Analkarzinom

Author

Schmoll, H.-J., Roelofsen, F., Dunst, J., Schlag, P.M., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
1999
Full Text
View/download PDF

31. Harnblasenkarzinom

Author

Schöffski, P., Dunst, J., Herr, H. W., Höltl, H., Schmoll, H.-J., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
1997
Full Text
View/download PDF

32. Analkarzinom

Author

Schmoll, H. J., Dunst, J., Schlag, P. M., Schmoll, Hans-Joachim, editor, Höffken, Klaus, editor, and Possinger, Kurt, editor

Published
1997
Full Text
View/download PDF

33. Integration of radiation oncology teaching in medical studies by German medical faculties due to the new licensing regulations

Author

Dapper, H., Belka, C., Bock, F., Budach, V., Budach, W., Christiansen, H., Debus, J., Distel, L., Dunst, J., Eckert, F., Eich, H., Eicheler, W., Engenhart-Cabillic, R., Fietkau, R., Fleischmann, D. F., Frerker, B., Giordano, F. A., Grosu, A. L., Herfarth, K., Hildebrandt, G., Kaul, D., Kölbl, O., (0000-0003-1776-9556) Krause, M., Krug, D., Martin, D., Matuschek, C., Medenwald, D., Nicolay, N. H., Niewald, M., Oertel, M., Petersen, C., Pohl, F., Raabe, A., Rödel, C., Rübe, C., Schmalz, C., Schmeel, L. C., Steinmann, D., Stüben, G., Thamm, R., Vordermark, D., Vorwerk, H., Wiegel, T., Zips, D., Combs, S. E., Dapper, H., Belka, C., Bock, F., Budach, V., Budach, W., Christiansen, H., Debus, J., Distel, L., Dunst, J., Eckert, F., Eich, H., Eicheler, W., Engenhart-Cabillic, R., Fietkau, R., Fleischmann, D. F., Frerker, B., Giordano, F. A., Grosu, A. L., Herfarth, K., Hildebrandt, G., Kaul, D., Kölbl, O., (0000-0003-1776-9556) Krause, M., Krug, D., Martin, D., Matuschek, C., Medenwald, D., Nicolay, N. H., Niewald, M., Oertel, M., Petersen, C., Pohl, F., Raabe, A., Rödel, C., Rübe, C., Schmalz, C., Schmeel, L. C., Steinmann, D., Stüben, G., Thamm, R., Vordermark, D., Vorwerk, H., Wiegel, T., Zips, D., and Combs, S. E.

Abstract

The new Medical Licensing Regulations 2025 (Ärztliche Approbationsordnung, ÄApprO) will soon be passed by the Federal Council (Bundesrat) and will be implemented step by step by the individual faculties in the coming months. The further development of medical studies essentially involves an orientation from fact-based to competence-based learning and focuses on practical, longitudinal and interdisciplinary training. Radiation oncology and radiation therapy are important components of therapeutic oncology and are of great importance for public health, both clinically and epidemiologically, and therefore should be given appropriate attention in medical education. This report is based on a recent survey on the current state of radiation therapy teaching at university hospitals in Germany as well as the contents of the National Competence Based Learning Objectives Catalogue for Medicine 2.0 (Nationaler Kompetenzbasierter Lernzielkatalog Medizin 2.0, NKLM) and the closely related Subject Catalogue (Gegenstandskatalog, GK) of the Institute for Medical and Pharmaceutical Examination Questions (Institut für Medizinische und Pharmazeutische Prüfungsfragen, IMPP). The current recommendations of the German Society for Radiation Oncology (Deutsche Gesellschaft für Radioonkologie, DEGRO) regarding topics, scope and rationale for the establishment of radiation oncology teaching at the respective faculties are also included.

Published
2022

34. Harnblase

Author

Dunst, J., Sauer, R., Scherer, Eberhard, editor, and Sack, Horst, editor

Published
1996
Full Text
View/download PDF

46. Integration of radiation oncology teaching in medical studies by German medical faculties due to the new licensing regulations

Author

Dapper, H., primary, Belka, C., additional, Bock, F., additional, Budach, V., additional, Budach, W., additional, Christiansen, H., additional, Debus, J., additional, Distel, L., additional, Dunst, J., additional, Eckert, F., additional, Eich, H., additional, Eicheler, W., additional, Engenhart-Cabillic, R., additional, Fietkau, R., additional, Fleischmann, D. F., additional, Frerker, B., additional, Giordano, F. A., additional, Grosu, A. L., additional, Herfarth, K., additional, Hildebrandt, G., additional, Kaul, D., additional, Kölbl, O., additional, Krause, M., additional, Krug, D., additional, Martin, D., additional, Matuschek, C., additional, Medenwald, D., additional, Nicolay, N. H., additional, Niewald, M., additional, Oertel, M., additional, Petersen, C., additional, Pohl, F., additional, Raabe, A., additional, Rödel, C., additional, Rübe, C., additional, Schmalz, C., additional, Schmeel, L. C., additional, Steinmann, D., additional, Stüben, G., additional, Thamm, R., additional, Vordermark, D., additional, Vorwerk, H., additional, Wiegel, T., additional, Zips, D., additional, and Combs, S. E., additional

Published
2021
Full Text
View/download PDF

47. Long-Term Characterization of MRI-Morphologic Alterations After Active Motion-Compensated Liver SBRT

Author

Sarria, G.R., primary, Dreher, C., additional, Miebach, G., additional, Henkenberens, C., additional, Stera, S., additional, Wojtal, P., additional, Krug, D., additional, Oppitz, H., additional, Giordano, F.A., additional, Schäfer, J.J., additional, Lohr, F., additional, Dunst, J., additional, Blanck, O., additional, and Boda-Heggemann, J., additional

Published
2021
Full Text
View/download PDF

48. Is the simultaneously integrated boost (SIB) technique for early breast cancer ready to be adopted for routine adjuvant radiotherapy?: Statement of the German and the Austrian Societies of Radiooncology (DEGRO/ÖGRO)

Author

Sedlmayer, F., Sautter-Bihl, M.L., Budach, W., Dunst, J., Feyer, P., Fietkau, R., Haase, W., Harms, W., Rödel, C., Souchon, R., Wenz, F., Sauer, R., and Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO)

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results