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9 results on '"Dundua Mg"'

1. Somatotropin secretion in hyperprolactinemia

Author

Sabakhtarashvili Ma, Gorgoshidze Bv, Kurashvili Rb, Dundua Mg, and É. G. Veinberg

Subjects
Adenoma, Adult, Blood Glucose, medicine.medical_specialty, Somatotropic cell, Adolescent, Glucose challenge, Lactation Disorders, Biology, Basal (phylogenetics), Pituitary adenoma, Pregnancy, Internal medicine, medicine, Humans, In patient, Pituitary Neoplasms, Circadian rhythm, Pituitary microadenoma, Somatotropin secretion, General Neuroscience, Galactorrhea, medicine.disease, Circadian Rhythm, Prolactin, Endocrinology, Growth Hormone, Female
Abstract

1. HPL patients characteristically show depressed basal levels of STH. 2. Patients with HPL and radiologically confirmed pituitary adenoma show an altered response of the somatotropic structures to glucose challenge and marked circadian variations in the STH circadian pattern. 3. In patients without a radiological sign of pituitary adenoma STH levels are depressed but the circadian rhythm resembles the normal pattern; the STH fails to show a response to a glucose load and in GTT the STH concentration plot is flattened. 4. The severity of somatotropic functional alteration in HPL is not as important as the nature of the pathologic substrate which underlies the disease. 5. Studies on the circadian STH pattern and its fluctuations in GTT may provide objective criteria in the diagnosis of pituitary microadenoma.

Published
1983

2. [Cortisol secretion in patients with hyperprolactinemia syndrome].

Author

Veinberg EG, Kurashvili RB, Sabakhtarashvili MA, Gorgoshidze BV, and Dundua MG

Subjects
Adenoma physiopathology, Adolescent, Adult, Circadian Rhythm, Female, Humans, Pituitary Neoplasms physiopathology, Hydrocortisone metabolism, Prolactin blood
Published
1984

3. [Effect of streptodecase on the focus of the lesion in relation to initial ECG findings in patients with acute myocardial infarction].

Author

Iosava KV, Andriadze NA, Kurashvili RB, Volobuev IuIu, and Dundua MG

Subjects
Adult, Aged, Clinical Trials as Topic, Electrocardiography, Female, Heart Ventricles drug effects, Humans, Male, Middle Aged, Myocardial Infarction diagnosis, Myocardial Infarction pathology, Necrosis, Myocardial Infarction drug therapy, Myocardium pathology, Streptokinase therapeutic use
Published
1989

5. [Characteristics of growth hormone secretion in the hyperprolactinemia syndrome].

Author

Gorgoshidze BV, Sabakhtarashvili MA, Veĭnberg EG, Kurashvili RB, and Dundua MG

Subjects
Adenoma diagnosis, Adenoma physiopathology, Adolescent, Adult, Circadian Rhythm, Female, Humans, Pituitary Gland, Anterior physiopathology, Pituitary Neoplasms diagnosis, Pituitary Neoplasms physiopathology, Syndrome, Growth Hormone metabolism, Prolactin blood
Abstract

A low basal level of growth hormone (GH) was determined by radioimmunoassay in studying GH basal content, the circadian rhythm and the response to glucose load in patients with hyperprolactinemia. In subjects with hypophyseal adenoma, an anomalous GH response to glucose load and the disturbance of its circadian rhythm are seen. In patients not suffering from hypophyseal adenoma, the circadian curve of GH content is similar to the normal one on a lower level. A pronounced GH response to glucose load is absent in these patients.

Published
1983

6. [Carbohydrate metabolism in patients with hyperprolactinemia syndrome].

Author

Sabakhtarashvili MA, Gorgoshidze BV, Veĭnberg EG, Kurashvili RB, and Dundua MG

Subjects
Adolescent, Adult, Circadian Rhythm, Female, Glucose Tolerance Test, Humans, Pregnancy, Syndrome, Blood Glucose metabolism, Galactorrhea blood, Insulin blood, Lactation Disorders blood, Prolactin metabolism
Published
1983

7. [Comparative clinical characteristics of methods of digoxin microanalysis].

Author

Trusov VV, Zelenin AA, and Dundua MG

Subjects
Adult, Aged, Cardiovascular Diseases blood, Digoxin therapeutic use, Drug Resistance, Female, Half-Life, Humans, Immunoenzyme Techniques, Kinetics, Male, Middle Aged, Radioimmunoassay, Cardiovascular Diseases drug therapy, Digoxin blood
Published
1984

8. Somatotropin secretion in hyperprolactinemia.

Author

Gorgoshidze BV, Sabakhtarashvili MA, Veinberg EG, Kurashvili RB, and Dundua MG

Subjects
Adolescent, Adult, Blood Glucose metabolism, Circadian Rhythm, Female, Humans, Pregnancy, Adenoma blood, Galactorrhea blood, Growth Hormone blood, Lactation Disorders blood, Pituitary Neoplasms blood, Prolactin blood
Published
1983
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9. [Effect of 24-hour intravenous administration of nitroglycerin on the status of the focus of a lesion in patients with an acute myocardial infarct].

Author

Kavtaradze VG, Iosava KV, Andriadze NA, Kurashvili RB, and Dundua MG

Subjects
Acute Disease, Adult, Aged, Creatine Kinase blood, Electrocardiography, Humans, Infusions, Parenteral, Isoenzymes, Middle Aged, Nitroglycerin administration & dosage, Myocardial Infarction drug therapy, Nitroglycerin therapeutic use
Abstract

Nitroglycerin was drip-infused for 24 hours to 35 patients with acute myocardial infarction. Thirty-three patients were taken as controls. Intergroup comparisons were made of the patterns of precordial cartograms from 35 leads and serial measurements of plasma MB CPK activity. The treatment was shown to reduce significantly the activity of MB CPK and total ST elevation, the effect being particularly pronounced with the drug administered within the first 6 hours of the attack. It was also shown that 24-hour intravenous nitroglycerin infusion produced a significant decrease in the end diastolic pressure of the pulmonary artery that occurred by the 15th minute and persisted till the end of the administration.

Published
1985

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