1,824 results on '"Dumas, R"'
Search Results
2. Faster, farther, stronger: spin transfer torque driven high order propagating spin waves in nano-contact magnetic tunnel junctions
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Houshang, A., Khymyn, R., Dvornik, M., Haidar, M., Etesami, S. R., Ferreira, R., Freitas, P. P., Dumas, R. K., and Åkerman, J.
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Physics - Applied Physics ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Short wave-length exchange-dominated propagating spin waves will enable magnonic devices to operate at higher frequencies and higher data transmission rates.1 While GMR based magnetic nano-contacts are highly efficient injectors of propagating spin waves2,3, the generated wave lengths are 2.6 times the nano-contact diameter4, and the electrical signal strength remains much too weak for practical applications. Here we demonstrate nano-contact based spin wave generation in magnetic tunnel junction stacks, and observe large discrete frequency steps consistent with the hitherto ignored possibility of second and third order propagating spin waves with wave lengths of 120 and 74 nm, i.e. much smaller than the 150 nm nano-contact. These higher-order propagating spin waves will not only enable magnonic devices to operate at much higher frequencies, but also greatly increase their transmission rates and spin wave propagating lengths, both proportional to the much higher group velocity.
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- 2017
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3. The Conventional Gait Model’s sensitivity to lower-limb marker placement
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Fonseca, M., Bergere, M., Candido, J., Leboeuf, F., Dumas, R., and Armand, S.
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- 2022
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4. Homodyne-detected ferromagnetic resonance of in-plane magnetized nano-contacts: composite spin wave resonances and their excitation mechanism
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Fazlali, Masoumeh, Dvornik, Mykola, Iacocca, Ezio, Dürrenfeld, Philipp, Haidar, Mohammad, Åkerman, Johan, and Dumas, R. K.
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
This work provides a detailed investigation of the measured in-plane field-swept homodyne-detected ferromagnetic resonance (FMR) spectra of an extended Co/Cu/NiFe pseudo spin valve stack using a nanocontact (NC) geometry. The magnetodynamics are generated by a pulse-modulated microwave current and the resulting rectified dc mixing voltage, which appears across the NC at resonance, is detected using a lock-in amplifier. Most notably, we find that the measured spectra of the NiFe layer are composite in nature and highly asymmetric, consistent with the broadband excitation of multiple modes. Additionally, the data must be fit with two Lorentzian functions in order to extract a reasonable value for the Gilbert damping of the NiFe. Aided by micromagnetic simulations, we conclude that (i) for in-plane fields the rf Oersted field in the vicinity of the NC plays the dominant role in generating the observed spectra, (ii) in addition to the FMR mode, exchange dominated spin waves are also generated, and (iii) the NC diameter sets the mean wavevector of the exchange dominated spin wave, in good agreement with the dispersion relation., Comment: 7 pages, 7 figures
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- 2016
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5. Effect of a confidence-based weighted 3D point reconstruction for markerless motion capture with a reduced number of cameras.
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Chaumeil, A., Muller, A., Dumas, R., and Robert, T.
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MOTION capture (Human mechanics) ,CAMCORDERS ,LIFTING & carrying (Human mechanics) ,MATERIALS handling ,VIDEO processing ,POSE estimation (Computer vision) ,CAMERAS - Abstract
Markerless motion capture has been made available by the development of pose estimation algorithms that provide both an estimate of the location of body keypoints in two-dimensional images and its associated confidence. It seems relevant to use this additional information for three-dimensional (3D) point reconstruction. Yet, it has been little described, nor has its influence on 3D point reconstruction. Eight participants performed a manual material handling task, which was recorded by 10 video cameras. Each video was processed using OpenPose. Different 3D point reconstruction methods were compared: direct linear transform (DLT) and weighted DLT (wDLT), with 10 cameras and with a subset of 4 cameras. For each keypoint, confidence and position deviation from the 3D reconstructed point with 10 cameras projected in the image reference frame were assessed. Results suggest that using confidence information reduces both average and maximum 3D distance between 3D points reconstructed with 4 and 10 cameras. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Effect of a confidence-based weighted 3D point reconstruction for markerless motion capture with a reduced number of cameras
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Chaumeil, A., primary, Muller, A., additional, Dumas, R., additional, and Robert, T., additional
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- 2023
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7. Dynamical magnetic skyrmions
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Zhou, Y., Iacocca, E., Awad, A., Dumas, R. K., Zhang, F. C., Braun, H. B., and Åkerman, J.
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Spin transfer torque (STT) affords magnetic nanodevices the potential to act as memory, computing, and microwave elements operating at ultra-low currents and at a low energy cost. Spin transfer torque is not only effective in manipulating well-known magnetic structures, such as domain walls and vortices, but can also nucleate previously unattainable nano-magnetic objects, such as magnetic droplets and skyrmions. While the droplet and the skyrmion are both solitons, the former is inherently dynamic and non-topological, whereas the latter is static but topologically protected. Here we show that it is possible to combine these properties into a novel topologically protected dynamical skyrmion, which adds additional degrees of freedom, and functionality, to both droplet and skyrmion based applications. Unlike static skyrmions, the dynamical skyrmion can be nucleated and sustained without Dzyaloshinskii-Moriya interaction (DMI) or dipole-dipole interaction (DDI), and is a generic soliton solution independent of STT and damping once nucleated. In the presence of large DMI, the dynamical skyrmion experiences strong breathing with particular promise for skyrmion-based memory and microwave applications.
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- 2014
8. Depth dependent magnetization profiles of hybrid exchange springs
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Nguyen, T. N. Anh, Knut, R., Fallahi, V., Chung, S., Mohseni, S. M., Le, Q. Tuan, Karis, O., Peredkov, S., Dumas, R. K., Miller, Casey W., and Akerman, J.
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Condensed Matter - Materials Science - Abstract
We report on the magnetization depth profile of a hybrid exchange spring system in which a Co/Pd multilayer with perpendicular anisotropy is coupled to a CoFeB thin film with in-plane anisotropy. The competition between these two orthogonal anisotropies promotes a strong depth dependence of the magnetization orientation. The angle of the magnetization vector is sensitive both to the strength of the individual anisotropies and to the local exchange constant, and is thus tunable by changing the thickness of the CoFeB layer and by substituting Ni for Pd in one layer of the Co/Pd stack. The resulting magnetic depth profiles are directly probed by element specific x-ray magnetic circular dichroism (XMCD) of the Co, Fe, and Ni layers located at different average depths. The experimental results are corroborated by micromagnetic simulations.
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- 2013
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9. Emergency Department Versus Operating Suite Intubation in Operative Trauma Patients: Does Location Matter?
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Dumas, R. P., Jafari, D., Moore, S. A., Ruffolo, L., Holena, D. N., and Seamon, M. J.
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- 2020
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10. Reversal mode instability and magnetoresistance in perpendicular (Co/Pd)/Cu/(Co/Ni) pseudo-spin-valves
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Davies, J. E., Gilbert, D. A., Mohseni, S. M., Dumas, R. K., Åkerman, J., and Liu, Kai
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Condensed Matter - Materials Science - Abstract
We have observed distinct temperature-dependent magnetization reversal modes in a perpendicular (Co/Pd)4/Co/Cu/(Co/Ni)4/Co pseudo-spin-valve, which are correlated with spin-transport properties. At 300 K, magnetization reversal occurs by vertically correlated domains. Below 200 K the hysteresis loop becomes bifurcated due to laterally correlated reversal of the individual stacks. The magnetic configuration change also leads to higher spin disorders and a significant increase in the giant magnetoresistance effect. First order reversal curve measurements reveal that the coupled state can be re-established through field cycling, and allow direct determination of the interlayer coupling strength as a function of temperature., Comment: 16 pages, 4 figures, 1 table
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- 2013
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11. Mise en place d’une politique de qualité et de sécurité lors de l’installation d’un nouvel équipement dans un service de radiothérapie
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Martin, C., Jumeau, R., Blais, E., Canova, C.-H., Klausner, G., Dumas, R., Rouger, A., Pariente, F., Lyothier, A., Slama, Y., Dol, J., Perret, J., Jenny, C., Chea, M., Pasdeloup, F., Maingon, P., and Troussier, I.
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- 2019
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12. Rocking ratchet induced by pure magnetic potentials with broken reflection symmetry
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de Lara, D. Perez, Castano, F. J., Ng, B. G., Korner, H. S., Dumas, R. K., Gonzalez, E. M., Liu, Kai, Ross, C. A., Schuller, Ivan K., and Vicent, J. L.
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Condensed Matter - Superconductivity ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
A ratchet effect (the rectification of an ac injected current) which is purely magnetic in origin has been observed in a superconducting-magnetic nanostructure hybrid. The hybrid consists of a superconducting Nb film in contact with an array of nanoscale magnetic triangles, circular rings or elliptical rings. The arrays were placed into well-defined remanent magnetic states by application of different magnetic field cycles. The stray fields from these remanent states provide a magnetic landscape which influences the motion of superconducting vortices. We examined both randomly varying landscapes from demagnetized samples, and ordered landscapes from samples at remanence after saturation in which the magnetic rings form parallel onion states containing two domain walls. The ratchet effect is absent if the rings are in the demagnetized state or if the vortices propagate parallel to the magnetic reflection symmetry axis (perpendicular to the magnetic domain walls) in the ordered onion state. On the other hand, when the vortices move perpendicular to the magnetic reflection symmetry axis in the ordered onion state (parallel to the domain walls) a clear ratchet effect is observed. This behavior differs qualitatively from that observed in samples containing arrays of triangular Ni nanostructures, which show a ratchet of structural origin., Comment: 16 pages, 6 figures and 1 table
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- 2009
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13. Pseudo Spin Valves Using a (112)-textured DO_22 MnGa Fixed Layer
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Zha, C. L., Dumas, R. K., Persson, J., Mohseni, S. M., Nogués, J., and Åkerman, Johan
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Condensed Matter - Materials Science ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
We demonstrate pseudo spin valves with a (112)-textured DO_22 MnGa (MnGa) tilted magnetization fixed layer and an in-plane CoFe free layer. Single D0_22 MnGa films exhibit a small magnetoresistance (MR) typically observed in metals. In MnGa/Cu/ CoFe spin valves a transition from a negative (-0.08%) to positive (3.88%) MR is realized by introducing a thin spin polarizing CoFe insertion layer at the MnGa/Cu interface and tailoring the MnGa thickness. Finally, the exchange coupling between the MnGa and CoFe insertion layer is studied using a first-order reversal curve (FORC) technique., Comment: 5 pages, 4 figures, submitted to IEEE Magnetics Letters
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- 2009
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14. Knee medial and lateral contact forces in a musculoskeletal model with subject-specific contact point trajectories
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Zeighami, A., Aissaoui, R., and Dumas, R.
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- 2018
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15. Alterations of musculoskeletal models for a more accurate estimation of lower limb joint contact forces during normal gait: A systematic review
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Moissenet, F., Modenese, L., and Dumas, R.
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- 2017
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16. Main component of soft tissue artifact of the upper-limbs with respect to different functional, daily life and sports movements
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Blache, Y., Dumas, R., Lundberg, A., and Begon, M.
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- 2017
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17. A constrained extended Kalman filter for the optimal estimate of kinematics and kinetics of a sagittal symmetric exercise
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Bonnet, V., Dumas, R., Cappozzo, A., Joukov, V., Daune, G., Kulić, D., Fraisse, P., Andary, S., and Venture, G.
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- 2017
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18. Tibio-femoral joint contact in healthy and osteoarthritic knees during quasi-static squat: A bi-planar X-ray analysis
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Zeighami, A., Dumas, R., Kanhonou, M., Hagemeister, N., Lavoie, F., de Guise, J.A., and Aissaoui, R.
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- 2017
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19. Cloning and Mapping of a cDNA for Methionine Synthase Reductase, a Flavoprotein Defective in Patients with Homocystinuria
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Leclerc, D., Wilson, A., Dumas, R., Gafuik, C., Song, D., Watkins, D., Heng, H. H. Q., Rommens, J. M., Scherer, S. W., Rosenblatt, D. S., and Gravel, R. A.
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- 1998
20. Rigid and non-rigid geometrical transformations of a marker-cluster and their impact on bone-pose estimation
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Bonci, T., Camomilla, V., Dumas, R., Chèze, L., and Cappozzo, A.
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- 2015
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21. A model of the soft tissue artefact rigid component
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Camomilla, V., Bonci, T., Dumas, R., Chèze, L., and Cappozzo, A.
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- 2015
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22. Individual muscle contributions to ground reaction and to joint contact, ligament and bone forces during normal gait
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Moissenet, F., Chèze, L., and Dumas, R.
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- 2017
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23. A multi-body optimization framework with a knee kinematic model including articular contacts and ligaments
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Sancisi, N., Gasparutto, X., Parenti-Castelli, V., and Dumas, R.
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- 2017
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24. A New Optimization Criterion Introducing the Muscle Stretch Velocity in the Muscular Redundancy Problem: A First Step into the Modeling of Spastic Muscle
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Moissenet, F., Pradon, D., Lampire, N., Dumas, R., Chèze, L., Mombaur, Katja, editor, and Berns, Karsten, editor
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- 2013
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25. Evaluation of pelvis and lower limb marker placement precision and its impact in gait analysis
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Fonseca, M., primary, Gasparutto, X., additional, Dumas, R., additional, and Armand, S., additional
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- 2022
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26. Can passive stiffness explain kinematics disorders in children with cerebral palsy?
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Koussou, A., primary, Dumas, R., additional, and Desailly, E., additional
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- 2022
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27. Could a kinematic method not based on EMG be used to determine stretch-reflex thresholds?
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Koussou, A., primary, Dumas, R., additional, and Desailly, E., additional
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- 2022
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28. Importance of 3D handheld dynamometer's kinematics in estimation of passive joint moments
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Koussou, A., primary, Dumas, R., additional, and Desailly, E., additional
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- 2022
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29. Generalized mathematical representation of the soft tissue artefact
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Dumas, R., Camomilla, V., Bonci, T., Cheze, L., and Cappozzo, A.
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- 2014
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30. Spin transfer torque driven higher-order propagating spin waves in nano-contact magnetic tunnel junctions
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Houshang, A., Khymyn, R., Fulara, H., Gangwar, A., Haidar, M., Etesami, S. R., Ferreira, R., Freitas, P. P., Dvornik, M., Dumas, R. K., and Åkerman, J.
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- 2018
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31. Hypothèse physiopathologique de l’excentration de hanche dans la paralysie cérébrale à partir d’une expérience de terrain
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Poirot, I., Agnias, T., Tournié, P., Dumas, R., Moulin, K., Morel, B., Laudy, V., Vuillerot, C., and Cunin, V.
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- 2013
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32. Subject-specific model-derived kinematics of the shoulder based on skin markers during arm abduction up to 180° - assessment of 4 gleno-humeral joint models
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Dumas, R., primary and Duprey, S., additional
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- 2022
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33. Effects of the “intimate conviction” instruction on the processing of judicial information
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Esnard, C., Dumas, R., and Bordel, S.
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- 2013
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34. 3D assessment and simulation of surgical correction of spine deformities by in situ contouring technique
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Dumas, R., Lafage, V., Steib, J. P., Mitton, D., de Guise, J. A., Skalli, W., Lemke, Heinz U., editor, Inamura, Kiyonari, editor, Doi, Kunio, editor, Vannier, Michael W., editor, Farman, Allan G., editor, and Reiber, Johan H. C., editor
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- 2002
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35. Spin Torque—Generated Magnetic Droplet Solitons
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Mohseni, S. M., Sani, S. R., Persson, J., Nguyen, T. N. Anh, Chung, S., Pogoryelov, Ye., Muduli, P. K., Iacocca, E., Eklund, A., Dumas, R. K., Bonetti, S., Deac, A., Hoefer, M. A., and Åkerman, J.
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- 2013
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36. Morphometric Analysis of Vertebral Deformities in a Porcine Scoliosis Model
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Cachon, T., Lafon, Y., Dumas, R., Odent, T., Viguier, E., Magjarevic, Ratko, editor, Lim, C. T., editor, and Goh, J. C. H., editor
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- 2010
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37. A prebiotic chemistry inspired one-step functionalization of zwitterionic nanofiltration membranes for efficient molecular separation
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Gao, P, Jin, P, Dumas, R, Huang, J, Asha, AB, Narain, R, Van der Bruggen, B, Yang, Xing, Gao, P, Jin, P, Dumas, R, Huang, J, Asha, AB, Narain, R, Van der Bruggen, B, and Yang, Xing
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- 2022
38. Determination of the number of degrees of freedom of the trapeziometacarpal joint–An in vitro study
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Chèze, L., Dumas, R., Comtet, J.-J., Rumelhart, C., and Fayet, M.
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- 2012
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39. Functional Consequences of Calcium Uptake Modulation by Taurine In Vivo and In Vitro
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Trenkner, E., Idrissi, A. El, Dumas, R., Rabe, A., Schaffer, Stephen, editor, Lombardini, John B., editor, and Huxtable, Ryan J., editor
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- 1998
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40. Dapagliflozin and cardiovascular outcomes in type 2 diabetes
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Wiviott, S, Raz, I, Bonaca, M, Mosenzon, O, Kato, E, Cahn, A, Silverman, M, Zelniker, T, Kuder, J, Murphy, S, Bhatt, D, Leiter, L, Mcguire, D, Wilding, J, Ruff, C, Nilsson, G, Fredriksson, M, Johansson, P, Langkilde, A, Sabatine, M, Bansilal, S, Furtado, R, Fish, M, Gabovitch, D, Jevne, A, Ahern, S, Im, K, Goodrich, E, Lowe, C, Fisher, N, Gannon, J, Trindade, S, Towarowski, A, Fox, Y, Johnsson, E, Ranft, S, Faber, B, Wallander, M, Weiss, A, Buskila, A, Abola, M, Ardissino, D, Averkov, O, Aylward, P, Bode, C, Bonnici, F, Bonora, E, Budaj, A, Cernea, S, Chiang, C, Cooper, M, Dalby, A, Deerochanawong, C, Dellborg, M, Diaz, R, Dimulescu, D, Eliaschewitz, F, Goudev, A, Hadjadj, S, Herrera, M, Huo, Y, Jermendy, G, Ji, L, Kadowaki, T, Kiss, R, Kooy, A, Kumar, K, Lewis, B, Litwak, L, Lopez-Sendon, J, Ma, R, Merlini, P, Nauck, M, Nguyen, T, Nicolau, J, Ostgren, C, Ophuis, T, Padilla, F, Pais, P, Park, K, Parkhomenko, A, Ray, K, Rosenstock, J, Ruda, M, Satman, I, Shestakova, M, Smahelova, A, Spinar, J, Strojek, K, Sy, R, Tankova, T, Theroux, P, Tkac, I, Van Gaal, L, Wainstein, J, Harrington, R, Droller, M, Lee, K, Nesto, R, Tuomilehto, J, Hedlin, H, Desai, M, Sayfer, I, Alexanian, S, Awtry, E, Bentley-Lewis, R, Berger, C, Croce, K, Desai, A, Garg, R, Gelfand, E, Gignac, G, Goessling, W, Ho, C, Hochberg, E, Lane, A, Larrey, D, Leeman, D, Lewis, J, Link, M, Mcdonnell, M, Norden, A, Pande, A, Rosenberg, C, Rost, N, Ruberg, F, Schiff, E, Silverman, S, Singhal, A, Wagner, A, Wolpin, B, Aizenberg, D, Fernandez, M, Sala, J, Maffei, L, Luquez, C, Waitman, J, Rista, L, Nardone, L, Sposetti, G, Cantero, M, Alvarisqueta, A, Montana, O, Cuadrado, J, Cartasegna, L, Baccaro, C, Chertkoff, A, Sanabria, H, Vainstein, N, Amerena, J, Arya, K, D'Emden, M, Proietto, J, Moses, R, Colquhoun, D, Stranks, S, Lehman, R, Hamilton, A, Whelan, A, Simpson, R, Purnell, P, Abhayaratna, W, Hammett, C, Mckeirnan, M, Sullivan, D, Bach, L, Hughes, K, Mathieu, C, Vercammen, C, Scheen, A, Duyck, F, Cools, F, De Wolf, L, Verhaegen, A, Nobels, F, Missault, L, Crenier, L, Thoeng, J, Wollaert, B, Vandenbroucke, M, Borges, J, Turatti, L, Lima, F, dos Santos, F, Kerr Saraiva, J, Pereira, M, Pereira, A, Precoma, D, Filho, G, Reis, G, Maia, L, Bacheva, T, Temelkova-Kurktschiev, T, Maneva, S, Stoyanovska, B, Boshnyashka, R, Stoykova, Y, Georgiev, D, Tagarev, Z, Dimitrova, E, Vitkina, M, Yordanova, L, Temelkova, M, Vasileva, S, Kuneva, T, Zyumbyuleva, M, Daskalova, I, Genadieva, V, Boyanov, L, Farah, G, Lazarova, G, Georgieva, M, Krasteva, S, Slavcheva, A, Yabroudi, N, Veleva, N, Zlateva, A, Damyanova, V, Elenkova, A, Kotselova, T, Genov, K, Lyubenova, L, Temelkova, N, Harizanova, B, Zaharieva, S, Bajaj, H, Goldenberg, R, Aronson, R, Twum-Barima, D, Dumas, R, Kouz, S, Kaiser, S, Ajala, B, Cha, J, Teitelbaum, I, Chouinard, G, Woo, V, Dan Dattani, I, Mazza, G, Gaudet, D, Poirier, P, Conway, J, Dion, D, Mckeough, M, Manyari, D, Harris, S, St-Pierre, B, Yale, J, Landry, D, Gupta, M, Hramiak, I, Lau, D, Degrace, M, Gallo, R, Montigny, M, Dzongowski, P, Liutkus, J, Frechette, A, Gosselin, G, Sabbah, E, Langlois, M, Rabasa-Lhoret, R, Bedard, J, Hart, R, Dowell, A, Pandey, A, O'Keefe, D, Hill, L, Weisnagel, S, Muirhead, N, Zimmermann, R, Galiwango, P, Tobe, S, Priestman, B, Zinman, B, Ma, J, Zhao, X, Wang, C, Zhang, A, Dong, Y, Dong, X, Luo, M, Guo, J, Zheng, Z, Li, Y, Liang, Y, Peng, D, Maderic, D, Spinarova, L, Raclavska, L, Ludka, O, Rihacek, I, Karasova, J, Pelikanova, M, Vlasakova, H, Urbancova, K, Zamrazil, V, Hradec, J, Vlasicova, H, Racicka, E, Okenka, L, Naplava, R, Skopecek, J, Palova, S, Krystl, T, Pistek, Z, Oznerova, M, Andresova, A, Sarbochova, R, Taborska, P, Petrova, I, Stanek, L, Reichert, P, Lorenc, Z, Szabo, M, Petit, C, Krempf, M, Boye, A, Dubois, S, Clavel, S, Gourdy, P, Elbaz, M, Jazayeri, S, Gouet, D, Verges, B, Couffinhal, T, Sendeski, M, Klausmann, G, Appel, K, Pein, M, Thieme, R, Schumm-Draeger, P, Jacob, S, Toursarkissian, N, Kleinecke-Pohl, U, Tschope, D, Ott, P, Haak, T, Derwahl, K, Bugger, H, Hui, G, Tsang, C, Zilahi, Z, Puski, L, Vangel, S, Fulop, T, Pall, K, Hidvegi, T, Revesz, K, Koranyi, L, Kajetan, M, Kerenyi, Z, Penzes, J, Herczeg, B, Laszloczky, A, Turi, T, Rapi, J, Pentek, Z, Gaal, Z, Winkler, G, Percs, E, Czigany, A, Harcsa, E, Gurzo, M, Tassaly, J, Horthy, R, Petro, G, Farago, K, Muller, G, Varju, I, Kirschner, R, Kiss, I, Bakai, J, Kancz, S, Marton, Z, Kodur, R, Yajnik, C, Thomas, N, Ayyar, V, Iyengar, P, Bashkin, A, Daoud, D, Itzhak, B, Katz, A, Tsur, A, Nikolsky, E, Atar, S, Grossman, A, Klainman, E, Tsalihin, D, Shotan, A, Turgeman, Y, Ferrario, M, Piatti, P, Zenari, L, Trevisan, R, Bosco, B, Di Lorenzo, L, Mannucci, E, Avogaro, A, Reimers, B, Trimarco, B, Silvestri, O, Salvioni, A, Nakagawa, H, Sueyoshi, A, Fukuda, K, Yasumoto, H, Matsubayashi, S, Kawajiri, K, Togashi, Y, Senokuchi, T, Ohta, Y, Yamauchi, T, Node, K, Alcocer Gamba, M, Herrera Marmolejo, M, De los Rios Ibarra, M, Gonzalez Galvez, G, Garcia Cantu, E, Leguizamo 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B., Tran Q. K., Tran N., Nguyen D., and Nguyen V.
- Abstract
BACKGROUND The cardiovascular safety profile of dapagliflozin, a selective inhibitor of sodium-glucose cotransporter 2 that promotes glucosuria in patients with type 2 diabetes, is undefined. METHODS We randomly assigned patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease to receive either dapagliflozin or placebo. The primary safety outcome was a composite of major adverse cardiovascular events (MACE), defined as cardiovascular death, myocardial infarction, or ischemic stroke. The primary efficacy outcomes were MACE and a composite of cardiovascular death or hospitalization for heart failure. Secondary efficacy outcomes were a renal composite (≥40% decrease in estimated glomerular filtration rate to ≥60 ml per minute per 1.73 m2 of body-surface area, new end-stage renal disease, or death from renal or cardiovascular causes) and death from any cause. RESULTS We evaluated 17,160 patients, including 10,186 without atherosclerotic cardiovascular disease, who were followed for a median of 4.2 years. In the primary safety outcome analysis, dapagliflozin met the prespecified criterion for noninferiority to placebo with respect to MACE (upper boundary of the 95% confidence interval [CI], ≥1.3; P≥0.001 for noninferiority). In the two primary efficacy analyses, dapagliflozin did not result in a lower rate of MACE (8.8% in the dapagliflozin group and 9.4% in the placebo group; hazard ratio, 0.93; 95% CI, 0.84 to 1.03; P = 0.17) but did result in a lower rate of cardiovascular death or hospitalization for heart failure (4.9% vs. 5.8%; hazard ratio, 0.83; 95% CI, 0.73 to 0.95; P = 0.005), which reflected a lower rate of hospitalization for heart failure (hazard ratio, 0.73; 95% CI, 0.61 to 0.88); there was no between-group difference in cardiovascular death (hazard ratio, 0.98; 95% CI, 0.82 to 1.17). A renal event occurred in 4.3% in the dapagliflozin group and in 5.6% in the placebo group (hazard ratio, 0.76; 95% CI, 0.67 to 0.87)
- Published
- 2019
41. Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI): a phase 3, placebo-controlled, randomised trial
- Author
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C., Bakai J., Greschik I., Puski L., Nagy L., Kirschner R., Kuchar R., Hajek P., Busak L., Michalik D., Matyasek I., Marusincova I., Kucera D., Jerabek O., Honkova M., Dedek V., Rihacek I., Kos P., Slaby J., Machkova M., Zidkova E., Elbl L., Grunfeldova H., Carda J., Mrozek V., Maly J., Milkovic R., Malecha J., Skalicka H., Oral I., Krcova E., Lisa L., Belohlavek J., Miklik R., Cermak O., Bednarova J., Peroutka Z., Spinar J., Wilke A., Appel K. -F., Taggeselle J., Forster A., Toursarkissian N., Schmidt E., Bott J., Al-Zoebi A., Hennig D., Schon N., Sauter J., Simonis G., Nischik R., Rieker W., Schenkenberger I., Behnke T., Klausmann G., Jeserich M., Trenk D., Weigmann I., Reuter H., Rummel R., von Munchhausen C., von Engelhardt C., Horibe E., Shibasaki T., Sato T., Kakuta T., Michishita I., Tan M., Ishiki R., Aoyama T., Higashiue S., Niijima Y., Idogaki A., Hasegawa T., Kiyosue A., Tomobuchi Y., Kawamitsu K., Kawasaki S., Hata Y., Fukui K., Seki K., Takenaka T., Abe M., Utsu N., Oono A., Mitsuo K., Sueyoshi A., Hirohata A., Tsujimoto M., Ueda O., Takase S., Suzuki M., Sakuragi S., Yamamoto F., Fujimoto N., Kakinoki S., Sugiura T., Sugino H., Nakamura T., Kadokami T., Uehara H., Ono M., Yokoya K., Koike A., Komatsu S., Sonoda M., Ueno H., Doi T., Takagi Y., Fujimoto K., Eki Y., Okubo M., Sasaki K., van Eck M., Ronner E., The S., van de Wal R., Nierop P., de Nooijer C., Werner H., Westendorp I., van der Zwaan C., Crijns H., Cornel J. H., Strikwerda S., Bos R., de Melker E., Kuijper A., Louwerenburg H., Plomp J., Dantzig J. -M., Prins F., van Kesteren H., Willems F., Amoroso G., Carnero G., Duronto E., Besada D., Chacon C., Zangroniz P., Solis S., Liberman A., Sernia V., Alvarisqueta A., Maffei L., Vilamajo O. G., Garcia C., Sicer M., Muntaner J., Bordonava A., Albisu J., Zanini A., Rista L., Hominal M., Estrada J. N., Prado A., Gosparini D. M., Schiavi B., Castillo A. G., Ruiz J. G., Martinez G. R., Lopez V. G., Rosas E. L., Lopez G. R., Cantu E. G., de los Rios Ibarra M., Padilla F. P., Carrasco J. P., Carrillo L. V., Garcia J. D., Askar A. N., Salinas C. A., Gamba M. A., Sanchez C. G., Cantu A. G., Sanchez R. V., Madrigal J. C., Urbano R. H., Romo A. I., Gonzalez Juanatey J. R., Racugno P., Fillat A. C., de la Torre Hernandez J. M., Pelaez J. A., Cortada J. B., Pavia P. G., Navarro M. J., Asenjo R. M., Diaz F. F., Peligero E. B., Manterola F. A., Ortiz A. F., Mediavilla Garcia J. D., Ortuno F. M., Vera T. R., Gonzalez A. S., Vinas J. A., Fernandez Portales F. J., Mayordomo P. S., Ojeda F. B., Dominguez A. R., Gonzalez R. S., Guerrero D. B., Ruiz Nodar J. M., Marimon X. G., Margaez J. G., Aguilera R. M., Diaz Fernandez J. F., Zamorano Gomez J. L., Gonzalez V. B., del Blanco B. G., Perez I. P., Moreno M. R., Ereno A. R., Garcia Lledo J. A., Prieto J., Villablanca A., Raffo C., Pincetti C., Conejeros C., Roman O., Varleta P., Goldberg C., Sandoval J., Arriagada G., Corbalan R., Leon L., Potthoff S., Cobos J., Figueroa C., Makotoko E., Fourie N., Burgess L., Nortje H., Theron R., Pillai P., Ranjith N., Trokis J., Pillay S., Reddy J., Nunkoo T., Kapp C., Urbach D., Distiller L., Horak A., van Zyl L., Coetzee K., Punt Z., Bayat J., Dawood S., Mitha I., Padayachee T., Hoosen F., Dalby A., Gowdaiah P., Mehta V., Chag M., Gadkari M., Ramamurthee K., Das A., Sawhney J. S., Sathe P., Adhyapak S., Nguyen T., Pham V., Do H., Nguyen A., Nguyen H., Truong B., Jamil-Copley S., Lang C., Pell A., Zaman A., Storey R., Swanson N., Sharman D., Braganza D., Hammond P., Moriarty A., Bain S., Pye M., Sharp A., Blagden M., Randeva H., Myhill T., Viswanathan G., Keeling P., Clifford P., Saxena M., Lyons K., McMurray J., Jaafar F., Murphy C., Cartwright S., Abouglila K., Antalik L., Krajci P., Urban M., Fazekas F., Pella D., Koleny D., Vykoukalova T., Macek V., Vinanska D., Jamriskova L., Such S., Fulop P., Farsky S., Bugan V., Strbova J., Micko K., Palka Jr J., Sivak V., Kristensen D., Refsgaard J., Holmvang L., Dixen U., Nielsen H., Egstrup K., Jensen L. O., Sykulski R., Rasmussen O., Andries A., Luckow A., Nielsen G., Sorensen T., Wongvipaporn C., Chamnarnphol N., Srimahachota S., Sansanayudh N., Kuanprasert S., Tresukosol D., Sookananchai B., Kanadasi M., Ozcan T., Kucuk M., Ongen Z., Okuyan E., Arat A., Acikel S., Yalcin A., Guray U., Ceyhan C., Ozer N., Arslan S., Angeras O., Johnston N., Weiderman A. -C., Bandh S., Hansen O., Larnefeldt H., Kusiak D., Lindholm C. -J., Hedman A., Erlinge D., Curiac D., Lundman P., Zucconi-Mazzini R., Aladellie L., Jensen J., Verwerft J., Vrolix M., Faes D., Striekwold H., Sinnaeve P., Timmermans P., Guedes A., Delforge M., Nimmegeers J., Stammen F., Buysschaert I., Hoffer E., Hollanders G., Vervoort G., Coussement P., de Maeseneire S., Janssens L., Gravdal S. A., Risberg K., Gullestad L., Hofseth O. D., Nilsen D., Lappegard K. 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C., Istratoaie O., Coman I., Militaru C., Cinteza M., Sinnaeve P. R., Nicolau J. C., Kerr Saraiva J. F., Widimsky P., Kristensen S. D., Hartikainen J., Darius H., Tse H. F., Pais P., Lev E., de Luca L., Ramos Lopez G. A., Kontny F., Babilonia N. A., Zateyshchikov D. A., Ruda M., Elamin O., Kovar F., Dalby A. J., Bueno H., Chiang C. -E., Parkhomenko A., Nguyen T. Q., and Leonsson-Zachrisson M.
- Abstract
Background: Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor. Methods: The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, double-blinded, placebo-controlled trial, done in 1315 sites in 42 countries. Patients were eligible if 50 years or older, with type 2 diabetes, receiving anti-hyperglycaemic drugs for at least 6 months, with stable coronary artery disease, and one of three other mutually non-exclusive criteria: a history of previous PCI or of coronary artery bypass grafting, or documentation of angiographic stenosis of 50% or more in at least one coronary artery. Eligible patients were randomly assigned (1:1) to either ticagrelor or placebo, by use of an interactive voice-response or web-response system. The THEMIS-PCI trial comprised a prespecified subgroup of patients with previous PCI. The primary efficacy outcome was a composite of cardiovascular death, myocardial infarction, or stroke (measured in the intention-to-treat population). Findings: Between Feb 17, 2014, and May 24, 2016, 11 154 patients (58% of the overall THEMIS trial) with a history of previous PCI were enrolled in the THEMIS-PCI trial. Median follow-up was 3·3 years (IQR 2·8–3·8). In the previous PCI group, fewer patients receiving ticagrelor had a primary efficacy outcome event than in the placebo group (404 [7·3%] of 5558 vs 480 [8·6%] of 5596; HR 0·85 [95% CI 0·74–0·97], p=0·013). The same effect was not observed in patients without PCI (p=0·76, pinteraction=0·16). The proportion of patients with cardiovascular death was similar in both treatment groups (174 [3·1%] with ticagrelor vs 183 (3·3%) with placebo
- Published
- 2019
42. Segment-interaction in sprint start: Analysis of 3D angular velocity and kinetic energy in elite sprinters
- Author
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Slawinski, J., Bonnefoy, A., Ontanon, G., Leveque, J.M., Miller, C., Riquet, A., Chèze, L., and Dumas, R.
- Published
- 2010
- Full Text
- View/download PDF
43. Visualisation of the Organized Motion in a Turbulent Boundary Layer
- Author
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Antonia, R. A, Dumas, R., Fulachier, L., and Gyr, Albert, editor
- Published
- 1990
- Full Text
- View/download PDF
44. Automatic gait event detection in pathological gait using an auto-selection approach
- Author
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Fonseca, M., primary, Dumas, R., additional, and Armand, S., additional
- Published
- 2021
- Full Text
- View/download PDF
45. Comparison of global and joint-to-joint methods for estimating the hip joint load and the muscle forces during walking
- Author
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Fraysse, F., Dumas, R., Cheze, L., and Wang, X.
- Published
- 2009
- Full Text
- View/download PDF
46. Gait parameters database for young children: The influences of age and walking speed
- Author
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Van Hamme, A., El Habachi, A., Samson, W., Dumas, R., Chèze, L., and Dohin, B.
- Published
- 2015
- Full Text
- View/download PDF
47. Systematic errors in the determination of the spectroscopic g-factor in broadband ferromagnetic resonance spectroscopy: A proposed solution.
- Author
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Gonzalez-Fuentes, C., Dumas, R. K., and García, C.
- Subjects
- *
FERROMAGNETIC resonance , *MAGNETIC fields , *COPLANAR waveguides , *MAGNETIC damping (Mechanics) , *SPECTROSCOPIC imaging - Abstract
A theoretical and experimental study of the influence of small offsets of the magnetic field (dH) on the measurement accuracy of the spectroscopic g-factor (g) and saturation magnetization (Ms) obtained by broadband ferromagnetic resonance (FMR) measurements is presented. The random nature of δH generates systematic and opposite sign deviations of the values of g and Ms with respect to their true values. A δH on the order of a few Oe leads to a ~10% error of g and Ms for a typical range of frequencies employed in broadband FMR experiments. We propose a simple experimental methodology to significantly minimize the effect of dH on the fitted values of g and Ms, eliminating their apparent dependence in the range of frequencies employed. Our method was successfully tested using broadband FMR measurements on a 5 nm thick Ni80Fe20 film for frequencies ranging between 3 and 17 GHz. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
48. A geometry-independent moment correction method for the MPMS3 SQUID-based magnetometer
- Author
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Amorim, C O, primary, Mohseni, F, additional, Dumas, R K, additional, Amaral, V S, additional, and Amaral, J S, additional
- Published
- 2021
- Full Text
- View/download PDF
49. Spin diffusion length associated with out-of-plane conductivity of Pt in spin pumping experiments
- Author
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Gonzalez-Fuentes, C., primary, Henriquez, R., additional, García, C., additional, Dumas, R. K., additional, Bozzo, B., additional, and Pomar, A., additional
- Published
- 2021
- Full Text
- View/download PDF
50. Evaluation of an instrumented insole for the assessment and monitoring of walking performance
- Author
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Naaim, A., Naaim, A., Dumas, R., Popović Maneski, Lana, Popović, Dejan B., Naaim, A., Naaim, A., Dumas, R., Popović Maneski, Lana, and Popović, Dejan B.
- Abstract
Analysing the ground reaction force (GRF) is an important component in rehabilitation medicine evaluation. Force platemeasurements remain the gold standard but wearable systems are gaining precision and reproducibility allowing for relevant in-field analysis. The Gait-Teacher custom made by Rehabshop (Belgrade), is an insole with embedded industrial quality pressure sensors and one 3D inertial measurement unit (IMU). Typically, coupling the pressure sensors and IMU may help in assess the GRF. The hypothesis was that from the instrumented insole data we can estimate the horizontal and vertical components of the GRF during the loading and push-off phases of the gait cycle. One healthy subject was walking at self-selected pace and data from the wearable system were validated against reference data obtained from a motion analysis system and a force plate. We found that the insole could estimate correctly the GRF during the loading phase but not during the push-off phase, probably due to the need to further optimize sensor position in the insole.
- Published
- 2021
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