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An Historic Building Recording was carried out, followed by a series of excavations for new services covered an area measuring 35.50m by 4m. The excavations were comprised of a single, linear trench that had a length of 35.20m a width of 0.80m and reached a maximum depth of 0.76m. Excavations uncovered a series of earlier services which cut through an earlier brick basement or patio surface adjoining the rear exterior walls. The backfill of these made up the majority of the ground making up the current rear of the property. New services were installed in the line of the previous services, minimising the disturbance of the rear garden. 56 New Street is an historic building, with the timber framed core perhaps dating to the 16 or 17th century, with later additions in the 19th and 20th centuries. The Georgian north front which faces the road is the most formal design element and was the principal elevation. The exterior of the rear of building is largely covered in a modern cementitious render. The ceiling opening out works showed that in general, the ceilings contain a mixture of historic timbers and modern. Some of the roofs have been felted and updated to include modern insulation. The opening out works in the Range 1 revealed that many of the walls retain their historic fabric. The opening out works in the Range 1 revealed that many of the walls retain their historic fabric. The opening out works in Range 2, block 1 revealed that the first and second floors were almost certainly built during the same phase, likely the 19th century when the front Georgian façade was inserted and the Inn was generally updated. The only exception is the rear rooms F7-8 and S6 which contain evidence of an earlier roof, and therefore is likely to be a different extension phase (probably late 19th century). The watching brief aimed to identify the presence or absence of significant archaeological remains, with a particular focus on the medieval period and any earlier phases of occupation. The only earlier surface encountered was a modern, brick-built floor surface, 12. It was truncated by a later installation of modern services. There was no further evidence of pre-existing structural elements or archaeological features underlying floor surface 12. The only other archaeological feature encountered was a cobble stone path, 11, located to the south of the house. As only a small amount was uncovered within the trench excavations, the true purpose was unclear. It was likely either an earlier stone path or a foundation for an exterior garden wall. No further archaeological features were uncovered.

Where archaeological horizons were encountered they were cleaned by hand and excavated appropriately. Standard John Moore Heritage Services techniques were employed throughout, involving the completion of a written record for each deposit encountered, with scale plans and section drawings compiled where appropriate. A photographic record was also produced. The resultant spoil from the works was visually scanned, especially for finds relating to any evidence relating to the late medieval and post-medieval use of the farm and any remains of any earlier structure(s) and use on the site. Across three of the 5 areas monitored on this site there was evidence of substantial disturbance. The main area of this disturbance was focused on Area 5, the Courtyard. The previous use of the land in agricultural work was clear and evidence of a tremendous amount of disturbance for the installation of the water tank was apparent across this area. The total lack of archaeological material across this site may also be attributed to this in large part. Little further insight to the earlier use of the area prior to the mid-20th century seems largely lost due to this intensive development within the courtyard, but better preservation seemed likely across the rear of the cottage and to the east of the Barn. The limited excavation trenches were unable to establish much information beyond this, however future development to the east or the north of these structures might yield better results than within the disturbed courtyard deposits.

Where archaeological horizons were encountered they were cleaned by hand and excavated appropriately. Standard John Moore Heritage Services techniques were employed throughout, involving the completion of a written record for each deposit encountered, with scale plans and section drawings compiled where appropriate. A photographic record was also produced. The monitoring of the groundworks at 31 Martins Lane resulted in little insight into the archaeological activity of the area, due in large part to the depths of the known archaeological horizons and the subsequent measures taken to avoid impacting on those potential resources. Throughout the monitoring, only approximately 15m x 1m of the service trench leading down to the southern property boundary proved deep enough to potentially encounter any archaeology. In these locations, no archaeology was observed.

An archaeologist was present on site during the course of all groundwork that had the potential to reveal or disturb archaeological remains; in this case excavation for the required stopcock. The monitoring of this repair trench confirmed that no archaeological horizons were encountered or impacted throughout the groundworks. All of the area impacted upon was localised to previously disturbed deposits from earlier actions associated with either installation or maintenance of the water service lines. No archaeologically significant finds were encountered. Records were generated of the precise location and depth of groundwork for future benefit in the event further repair to the area is required.

John Moore Heritage Services carried out an evaluation at The Woodyard, Bainton, Bicester, Oxfordshire (NGR SP 5773 2708). The site was located approximately 40m to the north of previously investigated medieval houses dated to the 10th to 12th centuries. In this single evaluation trench, only one ditch was found running on a N-S alignment and yielded 30 sherds of early medieval pottery of the same date.

John Moore Heritage Services carried out 42 trench evaluation at the Bletchingdon Park estate in Bletchingdon, Oxfordshire. 3 boundary ditches were found in the northern fields; all the remaining archaeological evidence came from the southern approach to the main house, all containing material predominantly medieval in date. Features of note were a number of substantial ditches and pits, a potential structural foundation wall, earlier landscaping evidence (including construction methods as well as dividing walls and ditches) and the earlier garden boundary wall and road leading to St Giles Church from Bletchingdon village.

Hintergrund: Das neuroendokrine Prostatakarzinom (NEC) ist eine seltene Tumorentität mit schlechter Prognose. Platin und Etoposid basierte Chemotherapie (PE) werden üblicherweise als Erstlinientherapie im fortgeschrittenen Tumorstadium angewandt. Zur Zweitlinien- und Folgetherapie existieren[zum vollständigen Text gelangen Sie über die oben angegebene URL], 44. gemeinsamen Tagung der Bayerischen Urologenvereinigung und der Österreichischen Gesellschaft für Urologie und Andrologie

John Moore Heritage Services carried out an evaluation at Fleece Yard, Market Hill, Buckingham (NGR SP 69586 34086). The area showed signs of heavy truncation from early and later Victorian residential use and 20th century commercial redevelopment. The only features within the area of impact were two early 19th century pits which contained brick and tile fragments, animal bone and a small amount of diagnostic pottery sherds. No evidence of Roman or medieval activities were seen within the study area.

Fragestellung: Die multiparametrische MRT (mpMRT) gewinnt zur Diagnostik von Prostatakarzinomen (PCa) zunehmend an Bedeutung und verbessert die Diagnose von signifikanten Prostatakarzinomen (SPCa) (Gleason-score ≥3+4). Zudem kann die Entscheidungsfindung zur Biopsie basierend auf European[zum vollständigen Text gelangen Sie über die oben angegebene URL], 63. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie

Fragestellung: Die multiparametrische MRT (mpMRT) verbessert die Diagnostik signifikanter Prostatakarzinome (SPCa) und der extraprostatischen Tumorausdehnung (EPE). Wir kombinierten präoperative mpMRT-Daten und klinische Parameter zu einem Risikomodell (RM) um das individuelle seitenspezifische[zum vollständigen Text gelangen Sie über die oben angegebene URL], 63. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie

The area of impact was watched for archaeological horizons but none were encountered. Standard John Moore Heritage Services techniques were employed throughout, involving the completion of a written record for each deposit encountered, with scale plans and section drawings compiled where appropriate. A photographic record was also produced. The resultant spoil from the works was visually scanned, especially for finds relating to Roman and Prehistoric periods. Again, none were found. Owing to the fact that the area under observation had most recently been utilized as a garage with a gravel drive, very little alteration was required in terms of excavation in the area.

We apply a quasi-model-independent strategy ("Sleuth") to search for new high p_T physics in approximately 100 pb^-1 of ppbar collisions at sqrt(s) = 1.8 TeV collected by the DZero experiment during 1992-1996 at the Fermilab Tevatron. Over thirty-two e mu X, W+jets-like, Z+jets-like, and 3(lepton/photon)X exclusive final states are systematically analyzed for hints of physics beyond the standard model. Simultaneous sensitivity to a variety of models predicting new phenomena at the electroweak scale is demonstrated by testing the method on a particular signature in each set of final states. No evidence of new high p_T physics is observed in the course of this search, and we find that 89% of an ensemble of hypothetical similar experimental runs would have produced a final state with a candidate signal more interesting than the most interesting observed in these data., Comment: 28 pages, 17 figures. Submitted to Physical Review D

Fragestellung: Die multiparametrische MRT (mpMRI) und gezielte MRT/TRUS-Fusionsbiopsien (FGB) detektieren signifikante Prostatakarzinome (sPC) akkurater als konventionelle TRUS-Biopsien allein. Die Fragestellung der vorliegenden Arbeit war es, die Detektionsrate der mpMRT und FGB verglichen [zum vollständigen Text gelangen Sie über die oben angegebene URL], 62. Kongress der Nordrhein-Westfälischen Gesellschaft für Urologie

This document represents an investigation of the potential for archaeological remains on land adjacent to 1 Kelmarsh Road, Clipston, Northamptonshire LE16 9RX (NGR SU 71474 81447). No remains of significance were present.

The purpose of the present study was to investigate the effect of interleukin-12 on apoptosis of chronic lymphatic leukemia (CLL) B cells. Apoptotic indices were determined in highly purified CD5(+) B lymphocytes isolated from peripheral blood of seven patients with histologically confirmed CLL. Interleukin-4 as a known inhibitor of apoptosis was used as control. Quantitative analysis of apoptosis was determined by cell death detection ELISA. Our findings indicate that interleukin-12 inhibits ex vivo apoptosis in a large proportion of B-CLL patients and may be closely involved in the pathogenesis of disease. Therefore, our results may help identify potential new therapeutic targets in this malignancy.