360 results on '"Dubois, Joëlle"'
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2. N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents
3. A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation
4. Phenothiazine- and Carbazole-Cyanochalcones as Dual Inhibitors of Tubulin Polymerization and Human Farnesyltransferase
5. Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase
6. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors
7. Methylene versus carbonyl bridge in the structure of new tubulin polymerization inhibitors with tricyclic A-rings
8. Discovery and preliminary structure–activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors
9. Studies on phenothiazines: New microtubule-interacting compounds with phenothiazine A-ring as potent antineoplastic agents
10. Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors
11. Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents
12. Studies on indolizines. Evaluation of their biological properties as microtubule-interacting agents and as melanoma targeting compounds
13. Green synthesis of a new series of pyroglutamides targeting human farnesyltransferase
14. Discovery of azaisoerianin derivatives as potential antitumors agents
15. Imidazopyridine-fused [1,3]-diazepinones: Synthesis and antiproliferative activity
16. Synthesis and biological evaluation of a new class of triazin–triazoles as potential inhibitors of human farnesyltransferase
17. Synthesis of polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth
18. Discovery of two new inhibitors of Botrytis cinerea chitin synthase by a chemical library screening
19. Synthesis and biological evaluation of fluoro analogues of antimitotic phenstatin
20. Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs
21. A Phenotypic Assay to Identify Chikungunya Virus Inhibitors Targeting the Nonstructural Protein nsP2
22. Synthesis and biological evaluation of a new series of phenothiazine-containing protein farnesyltransferase inhibitors
23. Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: Synthesis, cytotoxicity and antitubulin activity
24. Influence of the skeleton on the cytotoxicity of flavonoids
25. Design, synthesis and antiproliferative activities of biarylolefins based on polyhydroxylated and carbohydrate scaffolds
26. Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk.
27. Glycopeptide dendrimer colchicine conjugates targeting cancer cells
28. Ultrasounds-mediated 10-seconds synthesis of chalcones as potential farnesyltransferase inhibitors
29. Iodine(III)-mediated halogenations of acyclic monoterpenoids
30. Novel C2–C3′ N-peptide linked macrocyclic taxoids. Part 2: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives
31. Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity
32. Synthesis and Anticancer Properties of Oxazepines Related to Azaisoerianin and IsoCoQuines
33. Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands
34. Access to 3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro- N -acyliminium species: a new family of potent farnesyltransferase inhibitors
35. The catalytic role of tyrosine 254 in flavocytochrome b2 (L-lactate dehydrogenase from bakerʼs yeast): Comparison between the Y254F and Y254L mutant proteins
36. Une place à part ? Positionnement du psychomotricien dans une équipe pluridisciplinaire au sein d'un service de rhumatologie
37. Dibenzocyclooctynes: Effect of Aryl Substitution on Their Reactivity toward Strain-Promoted Alkyne–Azide Cycloaddition
38. Exploring isoxazoles and pyrrolidinones decorated with the 4,6‐dimethoxy‐1,3,5‐triazine unit as human farnesyltransferase inhibitors
39. One-Pot Synthesis of 2-Styrylindoles from Ortho-Substituted Chloroenynes
40. New indolizine–chalcones as potent inhibitors of human farnesyltransferase: Design, synthesis and biological evaluation
41. First Total Synthesis of Original Chalcone-Flavone Dimers as Cissampeloflavone Analogues
42. Phenothiazine-based CaaX competitive inhibitors of human farnesyltransferase bearing a cysteine, methionine, serine or valine moiety as a new family of antitumoral compounds
43. Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events
44. 1,3,5‐Oxadiazine Framework by Oxygen vs. Nitrogen Trapping of an N‐Acyliminium Ion Derived from N,O‐bis‐TMS Pyroglutamic Acid
45. Chemodivergent, Tunable, and Selective Iodine(III)-Mediated Bromo-Functionalizations of Polyprenoids
46. On the discovery of new potent human farnesyltransferase inhibitors: emerging pyroglutamic derivatives
47. Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase
48. Peptide chemistry applied to a new family of phenothiazine-containing inhibitors of human farnesyltransferase
49. Chemodivergent, Tunable, and Selective Iodine(III)-Mediated Bromo-Functionalizations of Polyprenoids
50. Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors
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