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Sileshi Dubale,1,2 Dereje Kebebe,1 Ahmed Zeynudin,3 Negera Abdissa,4 Sultan Suleman1 1School of Pharmacy and Laboratory of Drug Quality (JuLaDQ), Jimma University, Jimma, Oromia, Ethiopia; 2Department of Pharmacy, Mattu University, Mattu, Oromia, Ethiopia; 3Medical Laboratory School, Jimma University, Jimma, Oromia, Ethiopia; 4Department of Chemistry, Wallaga University, Nekemte, Oromia, EthiopiaCorrespondence: Sileshi Dubale; Sultan Suleman, Email sileshi.dubale@gmail.com; sultan.sulemanl@gmail.comBackground: The emergence and spread of resistant microbes continue to be a major public health concern. Effective treatment alternatives, particularly from traditionally used medicinal plants, are needed.Objective: The main objective of this study was to conduct phytochemical screening and antimicrobial activity evaluation of selected traditionally used medicinal plants in Ethiopia.Methods: The ethnomedicinal use value frequency index (FI) was used to select twelve medicinal plants. Phytochemical classes of compounds were screened using different standard methods. Anti-microbial activities of plant extracts were evaluated against Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, and Candida albicans. Minimum inhibitory concentrations were measured using the broth micro-dilution method. The data were analyzed using Statistical Package for the Social Sciences (SPSS) version 21.0 and the findings were presented descriptively and using non parametric one-way ANOVA analysis (Kruskal–Wallis/Ddunn’s test).Results: The phytochemical constituents identified were flavonoids, alkaloids, glycosides, phenols, saponins, steroids, and terpenoids, with flavonoids, alkaloids, and phenols being the most abundant. The crude extracts and chloroform fractions of the extracts showed an activity against the tested strains. The crude extract of Thalictrum rhynchocarpum Quart.-Dill. and A.Rich root demonstrated superior activity against all the tested st

Daniel Geleta,1 Abebe Kebede,2 Gebeyehu Bulcha,3 Hyder Usman,2 Kunuz Hajibediru,4 Selass kebede,2 Sileshi Dubale,2 Getu Degu5 1Tropical & Infectious Diseases, Jimma University, Jimma, Oromia, Ethiopia; 2Pharmaceutical science, Jimma University, Jimma, Oromia, Ethiopia; 3Health Communication and Health Behavior, Jimma University, Oromia, Ethiopia; 4Reproductive Health,Jimma University, Jimma, Oromia, Ethiopia; 5Epidemiology and Biostatistics, Bahir Dar University, Bahir Dar, Amhara, EthiopiaCorrespondence: Daniel Geleta P.O.Box: 378 Tel +125 911723400Fax +251 471111450; +251 471112040Email daninagaa2009@gmail.comBackground: Contraceptive use is internationally endorsed as a human right and an indicator of the highest standard of sexual and reproductive health life. But reports from countries including Ethiopia showed a lower and capricious rate due to wider factors. Thus, the current study aimed to determine the prevalence and the predictors of contraceptive use among women of the premenopausal period.Methods: A retrospective cross-sectional data analysis was performed from Ethiopian Demographic and Health survey 2019 in January 2021. A total of 3260 premenopausal women were included by stratified sampling, and data were analyzed using SPSS version 25 software. Data were initially analyzed descriptively, and tests were done for variable multicollinearity, and model goodness of fit and predictive capacity. Subsequently, bivariate and multivariable logistic regression analyses were performed successively for the crude and adjusted odds ratio, and finally declared variables with a p-value of < 0.05 as predictors of contraceptive use.Results: The study included 3260 women with an average age of 41.66 (standard deviation ± 3.9) years. The overall prevalence of contraceptive use was reported 17% and explained to vary by women’s age, place of residence, education level, wealth index, and current working statuses. However, only the age, education, and wealth index