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6. Correlation between histopathology properties of dartos tissue and the severity of penile curvature in hypospadias.

Author

Duarsa, Gede Wirya Kusuma, Tirtayasa, Pande Made Wisnu, Winarti, Ni Wayan, Michael, Andy, and Duarsa, Komang Harsa Abhinaya

Subjects
*PENIS curvatures, *HYPOSPADIAS, *CONGENITAL disorders, *HUMAN abnormalities, *HISTOPATHOLOGY
Abstract

Purpose: Hypospadias, one of the congenital anomalies commonly associated with some degrees of ventral penile curvature that may arise from malformation of dartos fascia, the chordee. Our study aims to determine the correlation between the histopathology properties of dartos fascia and the severity of ventral penile curvature in hypospadias. Materials and methods: One hundred hypospadias patients with various degrees of ventral penile curvature were included in this cross-sectional analytical study from 2020 to 2022. During hypospadias repair, ventral dartos fascia was excised and analyzed for the degree of collagen thickness and the severity of the fibrotic condition. Results: Out of 100 patients, the mean age was 6.58 + 4.28 years, who were classified as mild to moderate (66%) and severe (34%) ventral curvature cases. The analyses showed significant differences in the severity of fibrotic condition and collagen thickness of dartos fascia to the severity of penile ventral curvature with p-values of 0.002 and 0.017, respectively. Conclusions: The difference in histopathology properties of dartos fascia may affect the severity of penile curvature in hypospadias patients. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Barts flank-free modified supine position vs prone position in percutaneous nephrolithotomy: Systematic review and meta analysis.

Author

Ananda, I Gede Yogi Prema, Santosa, Kadek Budi, Yudiana, I Wayan, Tirtayasa, Pande Made Wisnu, Pramana, Ida Bagus Putra, Prayudi, Nyoman Gede, and Duarsa, Gede Wirya Kusuma

Subjects
PATIENT positioning, SUPINE position, PERCUTANEOUS nephrolithotomy, LENGTH of stay in hospitals, PATIENT preferences, NEPHROSTOMY, FLUOROSCOPY
Abstract

Introduction: Percutaneous Nephrolithotomy (PCNL) has been performed in various positions, including prone position and several modifications of supine position. The Barts flank-free modified supine (FFMS) position is a newly enhanced version of the supine positions. This study aims to compare the outcomes of Barts FFMS and prone position in PCNL. Methods: This study followed PRISMA 2020 guideline and was registered to PROSPERO CRD42024530426. Comprehensive search in PubMed, Sciencedirect, and Scopus was conducted until May 2024. Stone-free rates, complications, surgery duration, fluoroscopy duration, use of nephrostomy, and length of stay were collected. Data were analyzed using RevMan 5.4. Results: A total of 4 studies were included in this review. There was no significant difference in stone-free rates between Barts FFMS and prone positions (OR = 1.12, 95% CI 0.64-1.95, p = 0.70). There were no significant difference in incidence of fever (OR = 0.91, 95% CI 0.38-2.18, p = 0.84), need for blood transfusion (OR = 0.46, 95% CI 0.11-1.88, p = 0.28), and urine leakage (OR = 0.41, 95% CI 0.16-1.05, p = 0.06). The surgery duration was significantly shorter in Barts FFMS position than in prone position (MD = -15.48, 95% CI [(-26.42)-(-4.55)], p = 0.006). There was no significant difference in patients requiring nephrostomy (OR = 0.19, 95% CI 0.01-3.75, p = 0.28). There were no significant difference in fluoroscopy duration (MD = 0.27, 95% CI [(-6.85)-7.40], p = 0.94) and the length of hospital stay (MD = -0.20, 95% CI [(-0.74)-0.33], p = 0.46). Conclusions: The surgery duration was significantly shorter in Barts FFMS position than in prone position. There were no significant differences regarding stone-free rates, complications, fluoroscopy duration, use of nephrostomy, and length of hospital stay. This indicates that neither Barts FFMS nor prone position is superior, and the choice should be based on the surgeon's preference and the patient's clinical status. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Global Practice Patterns in the Evaluation of Non-Obstructive Azoospermia: Results of a World-Wide Survey and Expert Recommendations

Author

Shah, Rupin, primary, Rambhatla, Amarnath, additional, Atmoko, Widi, additional, Martinez, Marlon, additional, Ziouziou, Imad, additional, Kothari, Priyank, additional, Tadros, Nicholas, additional, Phuoc, Nguyen Ho Vinh, additional, Kavoussi, Parviz, additional, Harraz, Ahmed, additional, Salvio, Gianmaria, additional, Gul, Murat, additional, Hamoda, Taha, additional, Toprak, Tuncay, additional, Birowo, Ponco, additional, Ko, Edmund, additional, Arafa, Mohamed, additional, Ghayda, Ramy Abou, additional, Karthikeyan, Vilvapathy Senguttuvan, additional, Saleh, Ramadan, additional, Russo, Giorgio Ivan, additional, Pinggera, Germar-Michael, additional, Chung, Eric, additional, Savira, Missy, additional, Colpi, Giovanni M., additional, Zohdy, Wael, additional, Pescatori, Edoardo, additional, Park, Hyun Jun, additional, Fukuhara, Shinichiro, additional, Tsujimura, Akira, additional, Rojas-Cruz, Cesar, additional, Marino, Angelo, additional, Mak, Siu King, additional, Amar, Edouard, additional, Ibrahim, Wael, additional, Sindhwani, Puneet, additional, Alhathal, Naif, additional, Busetto, Gian Maria, additional, Hashimi, Manaf Al, additional, El-Sakka, Ahmed, additional, Ramazan, Asci, additional, Dimitriadis, Fotios, additional, Timpano, Massimiliano, additional, Jezek, Davor, additional, Altay, Baris, additional, Zylbersztejn, Daniel Suslik, additional, Wong, Michael YC, additional, Moon, Du Geon, additional, Wyns, Christine, additional, Gamidov, Safar, additional, Akhavizadegan, Hamed, additional, Franceschelli, Alessandro, additional, Aydos, Kaan, additional, Quang, Vinh Nguyen, additional, Ashour, Shedeed, additional, Dayel, Adel Al, additional, Al-Marhoon, Mohamed S., additional, Micic, Sava, additional, Binsaleh, Saleh, additional, Hussein, Alayman, additional, Elbardisi, Haitham, additional, Mostafa, Taymour, additional, Taha, Emad, additional, Ramsay, Jonathan, additional, Zachariou, Athanasios, additional, Abdelrahman, Islam Fathy Soliman, additional, Rajmil, Osvaldo, additional, Kalkanli, Arif, additional, Molina, Juan Manuel Corral, additional, Bocu, Kadir, additional, Duarsa, Gede Wirya Kusuma, additional, Ceker, Gokhan, additional, Serefoglu, Ege Can, additional, Bahar, Fahmi, additional, Gherabi, Nazim, additional, Kuroda, Shinnosuke, additional, Bouzouita, Abderrazak, additional, Gudeloglu, Ahmet, additional, Ceyhan, Erman, additional, Hasan, Mohamed Saeed Mohamed, additional, Musa, Muhammad Ujudud, additional, Motawi, Ahmad, additional, Chak-Lam, Cho, additional, Taniguchi, Hisanori, additional, Ho, Christopher Chee Kong, additional, Vazquez, Jesus Fernando Solorzano, additional, Mutambirwa, Shingai, additional, Gungor, Nur Dokuzeylul, additional, Bendayan, Marion, additional, Giulioni, Carlo, additional, Baser, Aykut, additional, Falcone, Marco, additional, Boeri, Luca, additional, Blecher, Gideon, additional, Kheradmand, Alireza, additional, Sethupathy, Tamilselvi, additional, Adriansjah, Ricky, additional, Narimani, Nima, additional, Konstantinidis, Charalampos, additional, Nguyen, Tuan Thanh, additional, Japari, Andrian, additional, Dolati, Parisa, additional, Singh, Keerti, additional, Ozer, Cevahir, additional, Sarikaya, Selcuk, additional, Sheibak, Nadia, additional, Bosco, Ndagijimana Jean, additional, Özkent, Mehmet Serkan, additional, Le, Sang Thanh, additional, Sokolakis, Ioannis, additional, Katz, Darren, additional, Smith, Ryan, additional, Truong, Manh Nguyen, additional, Le, Tan V., additional, Huang, Zhongwei, additional, Deger, Muslim Dogan, additional, Arslan, Umut, additional, Calik, Gokhan, additional, Franco, Giorgio, additional, Rashed, Ayman, additional, Kahraman, Oguzhan, additional, Andreadakis, Sotiris, additional, Putra, Rosadi, additional, Balercia, Giancarlo, additional, Khalafalla, Kareim, additional, Cannarella, Rossella, additional, Tuấn, Anh Đặng, additional, Meliegy, Amr El, additional, Zilaitiene, Birute, additional, Ramirez, Marlene Lizbeth Zamora, additional, Giacone, Filippo, additional, Calogero, Aldo E., additional, Makarounis, Konstantinos, additional, Jindal, Sunil, additional, Hoai, Bac Nguyen, additional, Banthia, Ravi, additional, Peña, Marcelo Rodriguez, additional, Moorthy, Dharani, additional, Adamyan, Aram, additional, Kulaksiz, Deniz, additional, Kandil, Hussein, additional, Sofikitis, Nikolaos, additional, Salzano, Ciro, additional, Jungwirth, Andreas, additional, Banka, Surendra Reddy, additional, Mierzwa, Tiago Cesar, additional, Turunç, Tahsin, additional, Jain, Divyanu, additional, Avoyan, Armen, additional, Salacone, Pietro, additional, Kadıoğlu, Ateş, additional, Gupta, Chirag, additional, Lin, Haocheng, additional, Shamohammadi, Iman, additional, Mogharabian, Nasser, additional, Barrett, Trenton, additional, Danacıoğlu, Yavuz Onur, additional, Crafa, Andrea, additional, Daoud, Salima, additional, Malhotra, Vineet, additional, Almardawi, Abdulmalik, additional, Selim, Osama Mohamed, additional, Moussa, Mohamad, additional, Haghdani, Saeid, additional, Duran, Mesut Berkan, additional, Kunz, Yannic, additional, Preto, Mirko, additional, Eugeni, Elena, additional, Nguyen, Thang, additional, Elshahid, Ahmed Rashad, additional, Suyono, Seso Sulijaya, additional, Parikesit, Dyandra, additional, Nada, Essam, additional, Orozco, Eduardo Gutiérrez, additional, Boitrelle, Florence, additional, Trang, Nguyen Thi Minh, additional, Jamali, Mounir, additional, Nair, Raju, additional, Ruzaev, Mikhail, additional, Gadda, Franco, additional, Thomas, Charalampos, additional, Ferreira, Raphael Henrique, additional, Gul, Umit, additional, Maruccia, Serena, additional, Kanbur, Ajay, additional, Kinzikeeva, Ella, additional, Abumelha, Saad, additional, Quang, Nguyen, additional, Kosgi, Raghavender, additional, Gokalp, Fatih, additional, Soebadi, Mohammad Ayodhia, additional, Paul, Gustavo Marquesine, additional, Sajadi, Hesamoddin, additional, Gupte, Deepak, additional, Ambar, Rafael F., additional, Sogutdelen, Emrullah, additional, Singla, Karun, additional, Basurkano, Ari, additional, Kim, Shannon Hee Kyung, additional, Gilani, Mohammad Ali Sadighi, additional, Nagao, Koichi, additional, Brodjonegoro, Sakti Ronggowardhana, additional, Rezano, Andri, additional, Elkhouly, Mohamed, additional, Mazzilli, Rossella, additional, Farsi, Hasan M. A., additional, Ba, Hung Nguyen, additional, Alali, Hamed, additional, Kafetzis, Dimitrios, additional, Long, Tran Quang Tien, additional, Alsaid, Sami, additional, Cuong, Hoang Bao Ngoc, additional, Oleksandr, Knigavko, additional, Mustafa, Akhmad, additional, Acosta, Herik, additional, Pai, Hrishikesh, additional, Şahin, Bahadır, additional, Arianto, Eko, additional, Teo, Colin, additional, Jayaprakash, Sanjay Prakash, additional, Rachman, Rinaldo Indra, additional, Yenice, Mustafa Gurkan, additional, Sefrioui, Omar, additional, Paghdar, Smit, additional, Priyadarshi, Shivam, additional, Tanic, Marko, additional, Alfatlawy, Noor Kareem, additional, Rizaldi, Fikri, additional, Vishwakarma, Ranjit B., additional, Kanakis, George, additional, Cherian, Dinesh Thomas, additional, Lee, Joe, additional, Galstyan, Raisa, additional, Keskin, Hakan, additional, Wurzacher, Jana, additional, Seno, Doddy Hami, additional, Noegroho, Bambang S., additional, Margiana, Ria, additional, Javed, Qaisar, additional, Castiglioni, Fabrizio, additional, Tanwar, Raman, additional, Puigvert, Ana, additional, Kaya, Coşkun, additional, Purnomo, Medianto, additional, Yazbeck, Chadi, additional, Amir, Azwar, additional, Borges, Edson, additional, Bellavia, Marina, additional, Deswanto, Isaac Ardianson, additional, V, Vinod K, additional, Liguori, Giovanni, additional, Minh, Dang Hoang, additional, Siddiqi, Kashif, additional, Colombo, Fulvio, additional, Zini, Armand, additional, Patel, Niket, additional, Çayan, Selahittin, additional, Al-Kawaz, Ula, additional, Ragab, Maged, additional, Hebrard, Guadalupe Hernández, additional, Hoffmann, Ivan, additional, Efesoy, Ozan, additional, Saylam, Barış, additional, and Agarwal, Ashok, additional

Published
2024
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12. A systematic review and meta-analysis of short- and long-term complications of early versus delayed penile prosthesis implantation in patients with ischemic priapism.

Author

Nanda De Niro, Agustin J., Duarsa, Gede Wirya Kusuma, Harvy Wicaksono, Marshal, Tirtayasa, Pande Made Wisnu, Santosa, Kadek Budi, Yudiana, I Wayan, and Prayudi, Nyoman Gede

Subjects
*PENILE prostheses, *SATISFACTION, *PRIAPISM, *CONFIDENCE intervals
Abstract

Background: This study determined pooled estimates of short- and long-term complications of early versus delayed implantation of penile prosthesis in patients with ischemic priapism. Methods: We searched Pubmed, ProQuest, Scopus, EBSCOHost, and other sources from January 1, 2013, to March 2023. All study designs were included except animal studies, review articles, and consensus documents. Of the 214 articles, four studies were included in the systematic review, and further meta-analysis included three studies (PROSPERO CRD42023411005). Results: The short-term complication rate was lower with early implantation than with later implantation (β= -2.08; 95% Confidence Interval [CI] = -3.54, -0.6; p = < 0.05). A similar value was also found in the pooled analysis for long-term outcomes, defined as overall satisfaction rate, which is better with early implantation than later (β = 2.18; 95% CI = 1.35, 3.02; p= < 0.05). Conclusions: The results of the pooled analysis confirmed that short-term complications were significantly lower with early implantation than with delayed implantation. Overall satisfaction rates were higher in early implantation than in delayed implantation of penile prostheses. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Knowledge, attitudes, and practices regarding male infertility: A cross-sectional study among infertile couples visiting fertility clinics in Indonesia’s urban areas

Author

Mushlih, Yusuf, primary, Adli, Imam, additional, Araysi, Leo Alfath, additional, Suryoadji, Kemal Akbar, additional, Indra Rachman, Rinaldo, additional, Nurullah, Ghifari, additional, Indy Christanto, Roberto Bagaskara, additional, Savira, Missy, additional, Shah, Rupin, additional, Agarwal, Ashok, additional, Widyahening, Indah Suci, additional, Pratama, Gita, additional, Duarsa, Gede Wirya Kusuma, additional, Adriansjah, Ricky, additional, Parikesit, Dyandra, additional, Atmoko, Widi, additional, Rasyid, Nur, additional, and Birowo, Ponco, additional

Published
2023
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19. Risk factors for urethrocutaneous fistula following hypospadias repair surgery in Indonesia

Author

Duarsa, Gede Wirya Kusuma, Tirtayasa, Pande Made Wisnu, Daryanto, Besut, Nurhadi, Pradana, Renaldo, Johan, Tarmono, Utomo, Trisula, Yuri, Prahara, Siregar, Safendra, Wahyudi, Irfan, Situmorang, Gerhard Reinaldi, Ansharullah Palinrungi, Muhammad Asykar, Hutasoit, Yonas Immanuel, Hutahaean, Andre Yudha Alfanius, Zulfiqar, Yevri, Sigumonrong, Yacobda H., Mirza, Hendy, Rodjani, Arry, and Kloping, Yudhistira Pradnyan

Published
2020
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20. Controversy and consensus on the management of elevated sperm DNA fragmentation in male infertility: A global survey, current guidelines, and expert recommendations

Author

Farkouh, Ala’a, Agarwal, Ashok, Hamoda, Taha Abo-Almagd Abdel-Meguid, Kavoussi, Parviz, Saleh, Ramadan, Zini, Armand, Arafa, Mohamed, Harraz, Ahmed M., Gul, Murat, Karthikeyan, Vilvapathy Senguttuvan, Durairajanayagam, Damayanthi, Rambhatla, Amarnath, Boitrelle, Florence, Chung, Eric, Birowo, Ponco, Toprak, Tuncay, Ghayda, Ramy Abou, Cannarella, Rossella, Phuoc, Nguyen Ho Vinh, Dimitriadis, Fotios, Russo, Giorgio I., Sokolakis, Ioannis, Mostafa, Taymour, Makarounis, Konstantinos, Ziouziou, Imad, Kuroda, Shinnosuke, Bendayan, Marion, Kaiyal, Raneen Sawaid, Japari, Andrian, Simopoulou, Mara, Rocco, Lucia, Garrido, Nicolas, Gherabi, Nazim, Bocu, Kadir, Kahraman, Oguzhan, Le, Tan V., Wyns, Christine, Tremellen, Kelton, Sarikaya, Selcuk, Lewis, Sheena, Evenson, Donald P., Ko, Edmund, Calogero, Aldo E., Bahar, Fahmi, Martinez, Marlon, Crafa, Andrea, Nguyen, Quang, Ambar, Rafael F., Colpi, Giovanni, Bakircioglu, Mustafa Emre, Henkel, Ralf, Kandil, Hussein, Serefoglu, Ege Can, Alarbid, Abdullah, Tsujimura, Akira, Kheradmand, Alireza, Anagnostopoulou, Christina, Marino, Angelo, Adamyan, Aram, Zilaitiene, Birute, Ozer, Cevahir, Pescatori, Edoardo, Vogiatzi, Paraskevi, Busetto, Gian Maria, Balercia, Giancarlo, Elbardisi, Haitham, Akhavizadegan, Hamed, Sajadi, Hesamoddin, Taniguchi, Hisanori, Park, Hyun Jun, Rosas, Israel Maldonado, Al-Marhoon, Mohamed, Gilani, Mohammad Ali Sadighi, Alhathal, Naif, Pinggera, Germar-Michael, Kothari, Priyank, Mogharabian, Nasser, Micic, Sava, Homa, Sheryl T., Darbandi, Sara, Long, Tran Quang Tien, Zohdy, Wael, Atmoko, Widi, Sabbaghian, Marjan, Ibrahim, Wael, Smith, Ryan P., Ho, Christopher Chee Kong, Rosette, Jean de la, El-Sakka, Ahmed I., Preto, Mirko, Zenoaga-Barbăroșie, Cătălina, Abumelha, Saad Mohammed, Baser, Aykut, Aydos, Kaan, Ramirez-Dominguez, Liliana, Kumar, Vijay, Ong, Teng Aik, Mierzwa, Tiago Cesar, Adriansjah, Ricky, Banihani, Saleem A., Bowa, Kasonde, Fukuhara, Shinichiro, Peña, Marcelo Rodriguez, Moussa, Mohamad, Ari, Umut Çağın, Cho, Chak-Lam, Tadros, Nicholas N., Ugur, Muhammet Rasit, Amar, Edouard, Falcone, Marco, Santer, Frederic Romain, Kalkanli, Arif, Karna, Keshab Kumar, Khalafalla, Kareim, Vishwakarma, Ranjit B., Finocchi, Federica, Giulioni, Carlo, Ceyhan, Erman, Çeker, Gökhan, Yazbeck, Chadi, Rajmil, Osvaldo, Yilmaz, Mehmet, Altay, Baris, Barrett, Trenton L., Ngoo, Kay Seong, Roychoudhury, Shubhadeep, Salvio, Gianmaria, Lin, Haocheng, Kadioglu, Ates, Timpano, Massimiliano, Avidor-Reiss, Tomer, Hakim, Lukman, Sindhwani, Puneet, Franco, Giorgio, Singh, Rajender, Giacone, Filippo, Ruzaev, Mikhail, Kosgi, Raghavender, Sofikitis, Nikolaos, Palani, Ayad, Calik, Gokhan, Kulaksız, Deniz, Jezek, Davor, Al Hashmi, Manaf, Drakopoulos, Panagiotis, Omran, Huda, Leonardi, Sofia, Celik-Ozenci, Ciler, Güngör, Nur Dokuzeylül, Ramsay, Jonathan, Amano, Toshiyasu, Sogutdelen, Emrullah, Duarsa, Gede Wirya Kusuma, Chiba, Koji, Jindal, Sunil, Savira, Missy, Boeri, Luca, Borges, Edson, Gupte, Deepak, Gokalp, Fatih, Hebrard, Guadalupe Hernández, Minhas, Suks, Shah, Rupin, Farkouh, Ala’a, Agarwal, Ashok, Hamoda, Taha Abo-Almagd Abdel-Meguid, Kavoussi, Parviz, Saleh, Ramadan, Zini, Armand, Arafa, Mohamed, Harraz, Ahmed M., Gul, Murat, Karthikeyan, Vilvapathy Senguttuvan, Durairajanayagam, Damayanthi, Rambhatla, Amarnath, Boitrelle, Florence, Chung, Eric, Birowo, Ponco, Toprak, Tuncay, Ghayda, Ramy Abou, Cannarella, Rossella, Phuoc, Nguyen Ho Vinh, Dimitriadis, Fotios, Russo, Giorgio I., Sokolakis, Ioannis, Mostafa, Taymour, Makarounis, Konstantinos, Ziouziou, Imad, Kuroda, Shinnosuke, Bendayan, Marion, Kaiyal, Raneen Sawaid, Japari, Andrian, Simopoulou, Mara, Rocco, Lucia, Garrido, Nicolas, Gherabi, Nazim, Bocu, Kadir, Kahraman, Oguzhan, Le, Tan V., Wyns, Christine, Tremellen, Kelton, Sarikaya, Selcuk, Lewis, Sheena, Evenson, Donald P., Ko, Edmund, Calogero, Aldo E., Bahar, Fahmi, Martinez, Marlon, Crafa, Andrea, Nguyen, Quang, Ambar, Rafael F., Colpi, Giovanni, Bakircioglu, Mustafa Emre, Henkel, Ralf, Kandil, Hussein, Serefoglu, Ege Can, Alarbid, Abdullah, Tsujimura, Akira, Kheradmand, Alireza, Anagnostopoulou, Christina, Marino, Angelo, Adamyan, Aram, Zilaitiene, Birute, Ozer, Cevahir, Pescatori, Edoardo, Vogiatzi, Paraskevi, Busetto, Gian Maria, Balercia, Giancarlo, Elbardisi, Haitham, Akhavizadegan, Hamed, Sajadi, Hesamoddin, Taniguchi, Hisanori, Park, Hyun Jun, Rosas, Israel Maldonado, Al-Marhoon, Mohamed, Gilani, Mohammad Ali Sadighi, Alhathal, Naif, Pinggera, Germar-Michael, Kothari, Priyank, Mogharabian, Nasser, Micic, Sava, Homa, Sheryl T., Darbandi, Sara, Long, Tran Quang Tien, Zohdy, Wael, Atmoko, Widi, Sabbaghian, Marjan, Ibrahim, Wael, Smith, Ryan P., Ho, Christopher Chee Kong, Rosette, Jean de la, El-Sakka, Ahmed I., Preto, Mirko, Zenoaga-Barbăroșie, Cătălina, Abumelha, Saad Mohammed, Baser, Aykut, Aydos, Kaan, Ramirez-Dominguez, Liliana, Kumar, Vijay, Ong, Teng Aik, Mierzwa, Tiago Cesar, Adriansjah, Ricky, Banihani, Saleem A., Bowa, Kasonde, Fukuhara, Shinichiro, Peña, Marcelo Rodriguez, Moussa, Mohamad, Ari, Umut Çağın, Cho, Chak-Lam, Tadros, Nicholas N., Ugur, Muhammet Rasit, Amar, Edouard, Falcone, Marco, Santer, Frederic Romain, Kalkanli, Arif, Karna, Keshab Kumar, Khalafalla, Kareim, Vishwakarma, Ranjit B., Finocchi, Federica, Giulioni, Carlo, Ceyhan, Erman, Çeker, Gökhan, Yazbeck, Chadi, Rajmil, Osvaldo, Yilmaz, Mehmet, Altay, Baris, Barrett, Trenton L., Ngoo, Kay Seong, Roychoudhury, Shubhadeep, Salvio, Gianmaria, Lin, Haocheng, Kadioglu, Ates, Timpano, Massimiliano, Avidor-Reiss, Tomer, Hakim, Lukman, Sindhwani, Puneet, Franco, Giorgio, Singh, Rajender, Giacone, Filippo, Ruzaev, Mikhail, Kosgi, Raghavender, Sofikitis, Nikolaos, Palani, Ayad, Calik, Gokhan, Kulaksız, Deniz, Jezek, Davor, Al Hashmi, Manaf, Drakopoulos, Panagiotis, Omran, Huda, Leonardi, Sofia, Celik-Ozenci, Ciler, Güngör, Nur Dokuzeylül, Ramsay, Jonathan, Amano, Toshiyasu, Sogutdelen, Emrullah, Duarsa, Gede Wirya Kusuma, Chiba, Koji, Jindal, Sunil, Savira, Missy, Boeri, Luca, Borges, Edson, Gupte, Deepak, Gokalp, Fatih, Hebrard, Guadalupe Hernández, Minhas, Suks, and Shah, Rupin

Abstract

Purpose Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose of this study was to investigate global practices related to the management of elevated SDF in infertile men, summarize the relevant professional society recommendations, and provide expert recommendations for managing this condition. Materials and Methods An online global survey on clinical practices related to SDF was disseminated to reproductive clinicians, according to the CHERRIES checklist criteria. Management protocols for various conditions associated with SDF were captured and compared to the relevant recommendations in professional society guidelines and the appropriate available evidence. Expert recommendations and consensus on the management of infertile men with elevated SDF were then formulated and adapted using the Delphi method. Results A total of 436 experts from 55 different countries submitted responses. As an initial approach, 79.1% of reproductive experts recommend lifestyle modifications for infertile men with elevated SDF, and 76.9% prescribe empiric antioxidants. Regarding antioxidant duration, 39.3% recommend 4–6 months and 38.1% recommend 3 months. For men with unexplained or idiopathic infertility, and couples experiencing recurrent miscarriages associated with elevated SDF, most respondents refer to ART 6 months after failure of conservative and empiric medical management. Infertile men with clinical varicocele, normal conventional semen parameters, and elevated SDF are offered varicocele repair immediately after diagnosis by 31.4%, and after failure of antioxidants and conservative measures by 40.9%. Sperm selection techniques and testicular sperm extraction are also management options for couples undergoing ART. For most questions, heterogenous practices were demonstrated. Conclusions This paper presents the results of a large global survey on the management of infertile men with elevat

Published
2023

21. Controversy and Consensus on Indications for Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations

Author

Agarwal, Ashok, Farkouh, Ala’a, Saleh, Ramadan, Abdel-Meguid Hamoda, Taha Abo-Almagd, Harraz, Ahmed M., Kavoussi, Parviz, Arafa, Mohamed, Salvio, Gianmaria, Rambhatla, Amarnath, Toprak, Tuncay, Gül, Murat, Phuoc, Nguyen Ho Vinh, Boitrelle, Florence, Birowo, Ponco, Ghayda, Ramy Abou, Cannarella, Rossella, Kuroda, Shinnosuke, Durairajanayagam, Damayanthi, Zini, Armand, Wyns, Christine, Sarikaya, Selcuk, Tremellen, Kelton, Mostafa, Taymour, Sokolakis, Ioannis, Evenson, Donald P., Henkel, Ralf, Zohdy, Wael, Chung, Eric, Ziouziou, Imad, Falcone, Marco, Russo, Giorgio I., Al-Hashimi, Manaf, Calogero, Aldo E., Ko, Edmund, Colpi, Giovanni, Lewis, Sheena, Serefoglu, Ege Can, Bahar, Fahmi, Martinez, Marlon, Nguyen, Quang, Ambar, Rafael F., Bakircioglu, Mustafa Emre, Kandil, Hussein, Mogharabian, Nasser, Sabbaghian, Marjan, Taniguchi, Hisanori, Tsujimura, Akira, Sajadi, Hesamoddin, Ibrahim, Wael, Atmoko, Widi, Vogiatzi, Paraskevi, Gunes, Sezgin, Gilani, Mohammad Ali Sadighi, Roychoudhury, Shubhadeep, Güngör, Nur Dokuzeylül, Hakim, Lukman, Adriansjah, Ricky, Kothari, Priyank, Jindal, Sunil, Amar, Edouard, Park, Hyun Jun, Long, Tran Quang Tien, Homa, Sheryl T., Karthikeyan, Vilvapathy Senguttuvan, Zilaitiene, Birute, Rosas, Israel Maldonado, Marino, Angelo, Pescatori, Edoardo, Ozer, Cevahir, Akhavizadegan, Hamed, Garrido, Nicolas, Busetto, Gian Maria, Adamyan, Aram, Al-Marhoon, Mohamed, Elbardisi, Haitham, Dolati, Parisa, Darbandi, Mahsa, Darbandi, Sara, Balercia, Giancarlo, Pinggera, Germar-Michael, Micic, Sava, Ho, Christopher Chee Kong, Moussa, Mohamad, Preto, Mirko, Zenoaga-Barbăroşie, Cătălina, Smith, Ryan P., Kosgi, Raghavender, Rosette, Jean de la, El-Sakka, Ahmed I., Abumelha, Saad Mohammed, Mierzwa, Tiago Cesar, Ong, Teng Aik, Banihani, Saleem A., Bowa, Kasonde, Fukuhara, Shinichiro, Boeri, Luca, Danacıoğlu, Yavuz Onur, Gokalp, Fatih, Selim, Osama Mohamed, Cho, Chak-Lam, Tadros, Nicholas N., Ugur, Muhammet Rasit, Ozkent, Mehmet Serkan, Chiu, Peter, Kalkanli, Arif, Khalafalla, Kareim, Vishwakarma, Ranjit B., Finocchi, Federica, Andreadakis, Sotiris, Giulioni, Carlo, Çeker, Gökhan, Ceyhan, Erman, Malhotra, Vineet, Yilmaz, Mehmet, Timpano, Massimiliano, Barrett, Trenton L., Kim, Shannon Hee Kyung, Ahn, Sun-Tae, Giacone, Filippo, Palani, Ayad, Duarsa, Gede Wirya Kusuma, Kadioglu, Ates, Gadda, Franco, Zylbersztejn, Daniel Suslik, Aydos, Kaan, Kulaksız, Deniz, Gupte, Deepak, Calik, Gokhan, Karna, Keshab Kumar, Drakopoulos, Panagiotis, Baser, Aykut, Kumar, Vijay, Molina, Juan Manuel Corral, Rajmil, Osvaldo, Ferreira, Raphael H., Leonardi, Sofia, Avoyan, Armen, Sogutdelen, Emrullah, Franco, Giorgio, Ramsay, Jonathan, Ramirez, Liliana, Shah, Rupin, Agarwal, Ashok, Farkouh, Ala’a, Saleh, Ramadan, Abdel-Meguid Hamoda, Taha Abo-Almagd, Harraz, Ahmed M., Kavoussi, Parviz, Arafa, Mohamed, Salvio, Gianmaria, Rambhatla, Amarnath, Toprak, Tuncay, Gül, Murat, Phuoc, Nguyen Ho Vinh, Boitrelle, Florence, Birowo, Ponco, Ghayda, Ramy Abou, Cannarella, Rossella, Kuroda, Shinnosuke, Durairajanayagam, Damayanthi, Zini, Armand, Wyns, Christine, Sarikaya, Selcuk, Tremellen, Kelton, Mostafa, Taymour, Sokolakis, Ioannis, Evenson, Donald P., Henkel, Ralf, Zohdy, Wael, Chung, Eric, Ziouziou, Imad, Falcone, Marco, Russo, Giorgio I., Al-Hashimi, Manaf, Calogero, Aldo E., Ko, Edmund, Colpi, Giovanni, Lewis, Sheena, Serefoglu, Ege Can, Bahar, Fahmi, Martinez, Marlon, Nguyen, Quang, Ambar, Rafael F., Bakircioglu, Mustafa Emre, Kandil, Hussein, Mogharabian, Nasser, Sabbaghian, Marjan, Taniguchi, Hisanori, Tsujimura, Akira, Sajadi, Hesamoddin, Ibrahim, Wael, Atmoko, Widi, Vogiatzi, Paraskevi, Gunes, Sezgin, Gilani, Mohammad Ali Sadighi, Roychoudhury, Shubhadeep, Güngör, Nur Dokuzeylül, Hakim, Lukman, Adriansjah, Ricky, Kothari, Priyank, Jindal, Sunil, Amar, Edouard, Park, Hyun Jun, Long, Tran Quang Tien, Homa, Sheryl T., Karthikeyan, Vilvapathy Senguttuvan, Zilaitiene, Birute, Rosas, Israel Maldonado, Marino, Angelo, Pescatori, Edoardo, Ozer, Cevahir, Akhavizadegan, Hamed, Garrido, Nicolas, Busetto, Gian Maria, Adamyan, Aram, Al-Marhoon, Mohamed, Elbardisi, Haitham, Dolati, Parisa, Darbandi, Mahsa, Darbandi, Sara, Balercia, Giancarlo, Pinggera, Germar-Michael, Micic, Sava, Ho, Christopher Chee Kong, Moussa, Mohamad, Preto, Mirko, Zenoaga-Barbăroşie, Cătălina, Smith, Ryan P., Kosgi, Raghavender, Rosette, Jean de la, El-Sakka, Ahmed I., Abumelha, Saad Mohammed, Mierzwa, Tiago Cesar, Ong, Teng Aik, Banihani, Saleem A., Bowa, Kasonde, Fukuhara, Shinichiro, Boeri, Luca, Danacıoğlu, Yavuz Onur, Gokalp, Fatih, Selim, Osama Mohamed, Cho, Chak-Lam, Tadros, Nicholas N., Ugur, Muhammet Rasit, Ozkent, Mehmet Serkan, Chiu, Peter, Kalkanli, Arif, Khalafalla, Kareim, Vishwakarma, Ranjit B., Finocchi, Federica, Andreadakis, Sotiris, Giulioni, Carlo, Çeker, Gökhan, Ceyhan, Erman, Malhotra, Vineet, Yilmaz, Mehmet, Timpano, Massimiliano, Barrett, Trenton L., Kim, Shannon Hee Kyung, Ahn, Sun-Tae, Giacone, Filippo, Palani, Ayad, Duarsa, Gede Wirya Kusuma, Kadioglu, Ates, Gadda, Franco, Zylbersztejn, Daniel Suslik, Aydos, Kaan, Kulaksız, Deniz, Gupte, Deepak, Calik, Gokhan, Karna, Keshab Kumar, Drakopoulos, Panagiotis, Baser, Aykut, Kumar, Vijay, Molina, Juan Manuel Corral, Rajmil, Osvaldo, Ferreira, Raphael H., Leonardi, Sofia, Avoyan, Armen, Sogutdelen, Emrullah, Franco, Giorgio, Ramsay, Jonathan, Ramirez, Liliana, and Shah, Rupin

Abstract

Purpose: Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of the World Health Organization laboratory manual for the examination and processing of human semen. Many conditions and risk factors have been associated with elevated SDF; therefore, it is important to identify the population of infertile men who might benefit from this test. The purpose of this study was to investigate global practices related to indications for SDF testing, compare the relevant professional society guideline recommendations, and provide expert recommendations. Materials and Methods: Clinicians managing male infertility were invited to take part in a global online survey on SDF clinical practices. This was conducted following the CHERRIES checklist criteria. The responses were compared to professional society guideline recommendations related to SDF and the appropriate available evidence. Expert recommendations on indications for SDF testing were then formulated, and the Delphi method was used to reach consensus. Results: The survey was completed by 436 experts from 55 countries. Almost 75% of respondents test for SDF in all or some men with unexplained or idiopathic infertility, 39% order it routinely in the work-up of recurrent pregnancy loss (RPL), and 62.2% investigate SDF in smokers. While 47% of reproductive urologists test SDF to support the decision for varicocele repair surgery when conventional semen parameters are normal, significantly fewer general urologists (23%; p=0.008) do the same. Nearly 70% would assess SDF before assisted reproductive technologies (ART), either always or for certain conditions. Recurrent ART failure is a common indication for SDF testing. Very few society recommendations were found regarding SDF testing. Conclusions: This article presents the largest global survey on the indications for SDF testing in infertile men, and demonstrates diverse practices. Furthermore, it highlights the paucity of professional society guideline

Published
2023

22. The Current Challenges in Diagnosing and Treating Malignant Priapism: A Comprehensive Review.

Author

Yudiana, I. Wayan, Sugianto, Ronald, Putri, Putu Eka Dianti, Ekawati, Ni Putu, and Duarsa, Gede Wirya Kusuma

Subjects
ONLINE information services, MEDICAL databases, PRIAPISM, PENILE tumors, MEDICAL information storage & retrieval systems, CARCINOGENESIS, SYSTEMATIC reviews, DESCRIPTIVE statistics, QUALITY of life, MEDLINE
Abstract

Malignant priapism (MP) is defined as a condition of persistent erection of the penis without sexual stimulation due to the neoplastic process of the cavernous sinus and the efferent veins. The effectiveness of established therapeutic recommendations in priapism was ineffective in MP. Modalities of therapy for MP varied from medication treatment, nonsurgical treatment, surgical treatment, and radiotherapy. Despite aggressive surgical management combined with radiation therapy, chemotherapy, or targeted therapy, the survival rate remains low. Therefore, the treatment is usually palliative, focusing on the patient's quality of life improvement and symptom relief. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
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26. Management of Male Infertility with Coexisting Sexual Dysfunction: A Consensus Statement and Clinical Recommendations from the Asia-Pacific Society of Sexual Medicine (APSSM) and the Asian Society of Men’s Health and Aging (ASMHA)

Author

Chung, Eric, primary, Hui, Jiang, additional, Xin, Zhong Cheng, additional, Kim, Sae Woong, additional, Moon, Du Geon, additional, Yuan, Yiming, additional, Nagao, Koichi, additional, Hakim, Lukman, additional, Chang, Hong-Chiang, additional, Mak, Siu King, additional, Duarsa, Gede Wirya Kusuma, additional, Dai, Yutian, additional, Yao, Bing, additional, Son, Hwancheol, additional, Huang, William, additional, Lin, Haocheng, additional, Nguyen, Quang, additional, Mai, Dung Ba Tien, additional, Park, Kwangsung, additional, Lee, Joe, additional, Tantiwongse, Kavirach, additional, Sato, Yoshikazu, additional, Jiann, Bang-Ping, additional, Ho, Christopher, additional, and Park, Hyun Jun, additional

Published
2023
Full Text
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27. Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations

Author

Shah, Rupin, Agarwal, Ashok, Kavoussi, Parviz, Rambhatla, Amarnath, Saleh, Ramadan, Cannarella, Rossella, Harraz, Ahmed M., Boitrelle, Florence, Kuroda, Shinnosuke, Hamoda, Taha Abo-Almagd Abdel-Meguid, Zini, Armand, Ko, Edmund, Çalık, Gökhan, Toprak, Tuncay, Kandil, Hussein, Gül, Murat, Bakırcıoğlu, Mustafa Emre, Parekh, Neel, Russo, Giorgio Ivan, Tadros, Nicholas, Kadıoğlu, Ateş, Arafa, Mohamed, Chung, Eric, Rajmil, Osvaldo, Dimitriadis, Fotios, Malhotra, Vineet, Salvio, Gianmaria, Henkel, Ralf, Le, Tan V., Sogutdelen, Emrullah, Vij, Sarah, Alarbid, Abdullah, Güdeloğlu, Ahmet, Tsujimura, Akira, Calogero, Aldo E., El Meliegy, Amr, Crafa, Andrea, Kalkanlı, Arif, Baser, Aykut, Hazır, Berk, Giulioni, Carlo, Cho, Chak-Lam, Ho, Christopher C.K., Salzano, Ciro, Zylbersztejn, Daniel Suslik, Tien, Dung Mai Ba, Pescatori, Edoardo, Borges, Edson, Saïs-Hamza, Eminej, Huyghe, Eric, Ceyhan, Erman, Caroppo, Ettore, Castiglioni, Fabrizio, Bahar, Fahmi, Gökalp, Fatih, Lombardo, Francesco, Gadda, Franco, Duarsa, Gede Wirya Kusuma, Pinggera, Germar-Michael, Busetto, Gian Maria, Balercia, Giancarlo, Cito, Gianmartin, Blecher, Gideon, Franco, Giorgio, Liguori, Giovanni, Elbardisi, Haitham, Keskin, Hakan, Lin, Haocheng, Taniguchi, Hisanori, Park, Hyun Jun, Ziouziou, Imad, de la Rosette, Jean J. M. C. H., Hotaling, Jim, Ramsay, Jonathan, Molina, Juan Manuel Corral, Lo, Ka Lun, Böcü, Kadir, Khalafalla, Kareim, Bowa, Kasonde, Okada, Keisuke, Nagao, Koichi, Chiba, Koji, Hakim, Lukman, Makarounis, Konstantinos, Hehemann, Marah, Peña, Marcelo Rodriguez, Falcone, Marco, Bendayan, Marion, Martinez, Marlon, Timpano, Massimiliano, Altan, Mesut, Fode, Mikkel, Al-Marhoon, Mohamed S., Gilani, Mohammad Ali Sadighi, Soebadi, Mohammad Ayodhia, Gherabi, Nazim, Sofikitis, Nikolaos, Kahraman, Oğuzhan, Birowo, Ponco, Kothari, Priyank, Sindhwani, Puneet, Javed, Qaisar, Ambar, Rafael F., Kosgi, Raghavender, Ghayda, Ramy Abou, Adriansjah, Ricky, Condorelli, Rosita Angela, La Vignera, Sandro, Micic, Sava, Kim, Shannon Hee Kyung, Fukuhara, Shinichiro, Ahn, Sun Tae, Mostafa, Taymour, Ong, Teng Aik, Takeshima, Teppei, Amano, Toshiyasu, Barrett, Trenton, Arslan, Umut, Karthikeyan, Vilvapathy Senguttuvan, Atmoko, Widi, Yumura, Yasushi, Yuan, Yiming, Kato, Yuki, Jezek, Davor, Cheng, Bryan Kwun-Chung, Hatzichristodoulou, Georgios, Dy, Jun, Castañé, Eduard Ruiz, El-Sakka, Ahmed I., Nguyen, Quang, Sarıkaya, Selçuk, Boeri, Luca, Tan, Ronny, Moussa, Mohamad A., El-Assmy, Ahmed, Alali, Hamed, Alhathal, Naif, Osman, Yasser, Perovic, Dragoljub, Sajadi, Hesamoddin, Akhavizadegan, Hamed, Vučinić, Miroslav, Kattan, Said, Kattan, Mohamed S., Mogharabian, Nasser, Phuoc, Nguyen Ho Vinh, Ngoo, Kay Seong, Alkandari, Mohammad H., Alsuhaibani, Shaheed, Sokolakis, Ioannis, Babaei, Mehdi, King, Mak Siu, Diemer, Thorsten, Gava, Marcelo M., Henrique, Raphael, Spinola e Silva, Rodrigo, Paul, Gustavo Marquesine, Mierzwa, Tiago Cesar, Glina, Sidney, Siddiqi, Kashif, Wu, Han, Wurzacher, Jana, Farkouh, Ala'a, Son, Hwancheol, Minhas, Suks, Lee, Joe, Magsanoc, Nikko, Capogrosso, Paolo, Albano, German Jose, Lewis, Sheena E.M., Jayasena, Channa N., Alvarez, Juan G., Teo, Colin, Smith, Ryan P., Chua, Jo Ben M., Jensen, Christian Fuglesang S., Parekattil, Sijo, Finelli, Renata, Durairajanayagam, Damayanthi, Karna, Keshab Kumar, Ahmed, Abdelkareem, Evenson, Don, Umemoto, Yukihiro, Puigvert, Ana, Çeker, Gökhan, Colpi, Giovanni M., Rolitsky, Sarah, Bouzouita, Abderrazak, Shokeir, Ahmed, Aşçı, Ahmet, Bouker, Amin, Adamyan, Aram, Avoyan, Armen E., Palani, Ayad, Aghamajidi, Azin, Eze, Balantine, Noegroho, Bambang Sasongko, Purnomo, Basuki, Erkan, Bircan Kolbaşı, Zilaitiene, Birute, Kulaksız, Deniz, Kafetzis, Dimitrios, Lee, Dong Sup, Stember, Doron, Evgeni, Evangelini, Alhajeri, Faisal, Finocchi, Federica, Colombo, Fulvio, Tsangaris, George, Sallam, Hassan N., Acosta, Herik, Rosas, Israel Maldonado, Kirkman-Brown, Jackson, Shin, Jae Il, Sonksen, Jens, Dong, Jie, Marmar, Joel, Moreno-Sepulveda, Jose, Seo, Ju Tae, Aydos, Kaan, Kesari, Kavindra Kumar, Trost, Landon, Jenkins, Lawrence, Rocco, Lucia, Darbandi, Mahsa, Simopoulou, Mara, Alves, Marco, Sabbaghian, Marjan, Tavalaee, Marziyeh, Razi, Mazdak, Duran, Mesut Berkan, Nago, Mitsuru, Elkhouly, Mohamed, Khalili, Mohamed, Nasr-Esfahani, Mohammad Hossein, Kamath, Mohan S., Uğur, Muhammet Raşit, Park, Nam Cheol, Cruz, Natalio, Garrido, Nicolas, Sodeifi, Niloofar, Al Khalidi, Noora, Shoshany, Ohad, Satyagraha, Paksi, Drakopoulos, Panagiotos, Vogiatzi, Paraskevi, Dolati, Parisa, Das, Partha, Chiu, Peter Ka-Fung, Tsioulou, Petroula A., Patel, Premal, Singh, Rajender, Kaiyal, Raneen Sawaid, Santos, Ferreira, Dada, Rima, Brodjonegoro, Sakti, Banihani, Saleem Ali, Schon, Samantha, Darbandi, Sara, Güneş, Sezgin, Homa, Sheryl, Mutambirwa, Shingai, Roychoudhury, Shubhadeep, Diaz, Sofia Ines Leonardi, Gopalakrishnan, Sreelatha, Krawetz, Stephen, Jindal, Sunil, Avidor-Reiss, Tomer, Lin, Tsung Yen, Kumar, Vijay, Ibrahim, Wael, Kerkeni, Walid, Woo, Wongi, Morimoto, Yoshiharu, Cheng, Yu-Sheng, Shah, Rupin, Agarwal, Ashok, Kavoussi, Parviz, Rambhatla, Amarnath, Saleh, Ramadan, Cannarella, Rossella, Harraz, Ahmed M., Boitrelle, Florence, Kuroda, Shinnosuke, Hamoda, Taha Abo-Almagd Abdel-Meguid, Zini, Armand, Ko, Edmund, Calik, Gokhan, Toprak, Tuncay, Kandil, Hussein, Gül, Murat, Bakırcıoğlu, Mustafa Emre, Parekh, Neel, Russo, Giorgio Ivan, Tadros, Nichola, Kadioglu, Ate, Arafa, Mohamed, Chung, Eric, Rajmil, Osvaldo, Dimitriadis, Fotio, Malhotra, Vineet, Salvio, Gianmaria, Henkel, Ralf, Le, Tan V., Sogutdelen, Emrullah, Vij, Sarah, Alarbid, Abdullah, Gudeloglu, Ahmet, Tsujimura, Akira, Calogero, Aldo E., Meliegy, Amr El, Crafa, Andrea, Kalkanli, Arif, Baser, Aykut, Hazir, Berk, Giulioni, Carlo, Cho, Chak-Lam, Ho, Christopher C. K., Salzano, Ciro, Zylbersztejn, Daniel Suslik, Tien, Dung Mai Ba, Pescatori, Edoardo, Borges, Edson, Serefoglu, Ege Can, Sas-Hamza, Emine, Huyghe, Eric, Ceyhan, Erman, Caroppo, Ettore, Castiglioni, Fabrizio, Bahar, Fahmi, Gokalp, Fatih, Lombardo, Francesco, Gadda, Franco, Duarsa, Gede Wirya Kusuma, Pinggera, Germar-Michael, Busetto, Gian Maria, Balercia, Giancarlo, Cito, Gianmartin, Blecher, Gideon, Franco, Giorgio, Liguori, Giovanni, Elbardisi, Haitham, Keskin, Hakan, Lin, Haocheng, Taniguchi, Hisanori, Park, Hyun Jun, Ziouziou, Imad, Rosette, Jean de la, Hotaling, Jim, Ramsay, Jonathan, Molina, Juan Manuel Corral, Lo, Ka Lun, Bocu, Kadir, Khalafalla, Kareim, Bowa, Kasonde, Okada, Keisuke, Nagao, Koichi, Chiba, Koji, Hakim, Lukman, Makarounis, Konstantino, Hehemann, Marah, Peña, Marcelo Rodriguez, Falcone, Marco, Bendayan, Marion, Martinez, Marlon, Timpano, Massimiliano, Altan, Mesut, Fode, Mikkel, Al-Marhoon, Mohamed S., Gilani, Mohammad Ali Sadighi, Soebadi, Mohammad Ayodhia, Gherabi, Nazim, Sofikitis, Nikolao, Kahraman, Oğuzhan, Birowo, Ponco, Kothari, Priyank, Sindhwani, Puneet, Javed, Qaisar, Ambar, Rafael F., Kosgi, Raghavender, Ghayda, Ramy Abou, Adriansjah, Ricky, Condorelli, Rosita Angela, Vignera, Sandro La, Micic, Sava, Kim, Shannon Hee Kyung, Fukuhara, Shinichiro, Ahn, Sun Tae, Mostafa, Taymour, Ong, Teng Aik, Takeshima, Teppei, Amano, Toshiyasu, Barrett, Trenton, Arslan, Umut, Karthikeyan, Vilvapathy Senguttuvan, Atmoko, Widi, Yumura, Yasushi, Yuan, Yiming, Kato, Yuki, Jezek, Davor, Cheng, Bryan Kwun-Chung, Hatzichristodoulou, Georgio, Dy, Jun, Castañé, Eduard Ruiz, El-Sakka, Ahmed I., Nguyen, Quang, Sarikaya, Selcuk, Boeri, Luca, Tan, Ronny, Moussa, Mohamad A., El-Assmy, Ahmed, Alali, Hamed, Alhathal, Naif, Osman, Yasser, Perovic, Dragoljub, Sajadi, Hesamoddin, Akhavizadegan, Hamed, Vučinić, Miroslav, Kattan, Said, Kattan, Mohamed S., Mogharabian, Nasser, Phuoc, Nguyen Ho Vinh, Ngoo, Kay Seong, Alkandari, Mohammad H., Alsuhaibani, Shaheed, Sokolakis, Ioanni, Babaei, Mehdi, King, Mak Siu, Diemer, Thorsten, Gava, Marcelo M., Henrique, Raphael, Silva, Rodrigo Spinola e, Paul, Gustavo Marquesine, Mierzwa, Tiago Cesar, Glina, Sidney, Siddiqi, Kashif, Wu, Han, Wurzacher, Jana, Farkouh, Ala’A, Son, Hwancheol, Minhas, Suk, Lee, Joe, Magsanoc, Nikko, Capogrosso, Paolo, Albano, German Jose, Lewis, Sheena E. M., Jayasena, Channa N., Alvarez, Juan G., Teo, Colin, Smith, Ryan P., Chua, Jo Ben M., Jensen, Christian Fuglesang S., Parekattil, Sijo, Finelli, Renata, Durairajanayagam, Damayanthi, Karna, Keshab Kumar, Ahmed, Abdelkareem, Evenson, Don, Umemoto, Yukihiro, Puigvert, Ana, Çeker, Gökhan, Forum, Giovanni M Colpi, Shah, R., Agarwal, A., Kavoussi, P., Rambhatla, A., Saleh, R., Cannarella, R., Harraz, A. M., Boitrelle, F., Kuroda, S., Hamoda, T. A. -A. A. -M., Zini, A., Ko, E., Calik, G., Toprak, T., Kandil, H., Gul, M., Bakircioglu, M. E., Parekh, N., Russo, G. I., Tadros, N., Kadioglu, A., Arafa, M., Chung, E., Rajmil, O., Dimitriadis, F., Malhotra, V., Salvio, G., Henkel, R., Le, T. V., Sogutdelen, E., Vij, S., Alarbid, A., Gudeloglu, A., Tsujimura, A., Calogero, A. E., El Meliegy, A., Crafa, A., Kalkanli, A., Baser, A., Hazir, B., Giulioni, C., Cho, C. -L., Ho, C. C. K., Salzano, C., Zylbersztejn, D. S., Tien, D. M. B., Pescatori, E., Borges, E., Serefoglu, E. C., Sais-Hamza, E., Huyghe, E., Ceyhan, E., Caroppo, E., Castiglioni, F., Bahar, F., Gokalp, F., Lombardo, F., Gadda, F., Duarsa, G. W. K., Pinggera, G. -M., Busetto, G. M., Balercia, G., Cito, G., Blecher, G., Franco, G., Liguori, G., Elbardisi, H., Keskin, H., Lin, H., Taniguchi, H., Park, H. J., Ziouziou, I., de la Rosette, J., Hotaling, J., Ramsay, J., Molina, J. M. C., Lo, K. L., Bocu, K., Khalafalla, K., Bowa, K., Okada, K., Nagao, K., Chiba, K., Hakim, L., Makarounis, K., Hehemann, M., Pena, M. R., Falcone, M., Bendayan, M., Martinez, M., Timpano, M., Altan, M., Fode, M., Al-Marhoon, M. S., Gilani, M. A. S., Soebadi, M. A., Gherabi, N., Sofikitis, N., Kahraman, O., Birowo, P., Kothari, P., Sindhwani, P., Javed, Q., Ambar, R. F., Kosgi, R., Ghayda, R. A., Adriansjah, R., Condorelli, R. A., La Vignera, S., Micic, S., Kim, S. H. K., Fukuhara, S., Ahn, S. T., Mostafa, T., Ong, T. A., Takeshima, T., Amano, T., Barrett, T., Arslan, U., Karthikeyan, V. S., Atmoko, W., Yumura, Y., Yuan, Y., Kato, Y., Jezek, D., Cheng, B. K. -C., Hatzichristodoulou, G., Dy, J., Castane, E. R., El-Sakka, A. I., Nguyen, Q., Sarikaya, S., Boeri, L., Tan, R., Moussa, M. A., El-Assmy, A., Alali, H., Alhathal, N., Osman, Y., Perovic, D., Sajadi, H., Akhavizadegan, H., Vucinic, M., Kattan, S., Kattan, M. S., Mogharabian, N., Phuoc, N. H. V., Ngoo, K. S., Alkandari, M. H., Alsuhaibani, S., Sokolakis, I., Babaei, M., King, M. S., Diemer, T., Gava, M. M., Henrique, R., Spinola e Silva, R., Paul, G. M., Mierzwa, T. C., Glina, S., Siddiqi, K., Wu, H., Wurzacher, J., Farkouh, A., Son, H., Minhas, S., Lee, J., Magsanoc, N., Capogrosso, P., Albano, G. J., Lewis, S. E. M., Jayasena, C. N., Alvarez, J. G., Teo, C., Smith, R. P., Chua, J. B. M., Jensen, C. F. S., Parekattil, S., Finelli, R., Durairajanayagam, D., Karna, K. K., Ahmed, A., Evenson, D., Umemoto, Y., Puigvert, A., Ceker, G., Colpi, G. M., Rolitsky, S., Bouzouita, A., Shokeir, A., Asci, A., Bouker, A., Adamyan, A., Avoyan, A. E., Palani, A., Aghamajidi, A., Eze, B., Noegroho, B. S., Purnomo, B., Erkan, B. K., Zilaitiene, B., Kulaksiz, D., Kafetzis, D., Lee, D. S., Stember, D., Evgeni, E., Alhajeri, F., Finocchi, F., Colombo, F., Tsangaris, G., Sallam, H. N., Acosta, H., Rosas, I. M., Kirkman-Brown, J., Shin, J. I., Sonksen, J., Dong, J., Marmar, J., Moreno-Sepulveda, J., Seo, J. T., Aydos, K., Kesari, K. K., Trost, L., Jenkins, L., Rocco, L., Darbandi, M., Simopoulou, M., Alves, M., Sabbaghian, M., Tavalaee, M., Razi, M., Duran, M. B., Nago, M., Elkhouly, M., Khalili, M., Nasr-Esfahani, M. H., Kamath, M. S., Ugur, M. R., Park, N. C., Cruz, N., Garrido, N., Sodeifi, N., Al Khalidi, N., Shoshany, O., Satyagraha, P., Drakopoulos, P., Vogiatzi, P., Dolati, P., Das, P., Chiu, P. K. -F., Tsioulou, P. A., Patel, P., Singh, R., Kaiyal, R. S., Santos, F., Dada, R., Brodjonegoro, S., Banihani, S. A., Schon, S., Darbandi, S., Gunes, S., Homa, S., Mutambirwa, S., Roychoudhury, S., Diaz, S. I. L., Gopalakrishnan, S., Krawetz, S., Jindal, S., Avidor-Reiss, T., Lin, T. Y., Kumar, V., Ibrahim, W., Kerkeni, W., Woo, W., Morimoto, Y., Cheng, Y. -S., and Tıp Fakültesi

Subjects
Aging, Consensus, Urology, INGUINAL VARICOCELECTOMY, Disease management, Male infertility, Survey, Varicocele, Consensu, Global Andrology Forum, Endocrinology & Metabolism, NONOBSTRUCTIVE AZOOSPERMIA, ASSISTED REPRODUCTIVE TECHNOLOGY, Male Infertility, Pharmacology (medical), Andrology, IMPAIRED SEMEN QUALITY, EUROPEAN ASSOCIATION, Science & Technology, UROLOGY GUIDELINES, Health Policy, Public Health, Environmental and Occupational Health, Disease Management, Urology & Nephrology, SUBCLINICAL VARICOCELE, Psychiatry and Mental health, Health Care Sciences & Services, MICROSURGICAL SUBINGUINAL VARICOCELECTOMY, Reproductive Medicine, SPERM MORPHOLOGY, UNTREATED VARICOCELE, Life Sciences & Biomedicine
Abstract

Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of consensus about the diagnosis, indications for VR and its outcomes. The aim of this study was to explore global practice patterns on the management of varicocele in the context of male infertility. Materials and Methods: Sixty practicing urologists/andrologists from 23 countries contributed 382 multiple-choice-questions pertaining to varicocele management. These were condensed into an online questionnaire that was forwarded to clinicians involved in male infertility management through direct invitation. The results were analyzed for disagreement and agreement in practice patterns and, compared with the latest guidelines of international professional societies (American Urological As- sociation [AUA], American Society for Reproductive Medicine [ASRM], and European Association of Urology [EAU]), and with evidence emerging from recent systematic reviews and meta-analyses. Additionally, an expert opinion on each topic was provided based on the consensus of 16 experts in the field. Results: The questionnaire was answered by 574 clinicians from 59 countries. The majority of respondents were urologists/ uro-andrologists. A wide diversity of opinion was seen in every aspect of varicocele diagnosis, indications for repair, choice of technique, management of sub-clinical varicocele and the role of VR in azoospermia. A significant proportion of the re- sponses were at odds with the recommendations of AUA, ASRM, and EAU. A large number of clinical situations were identi- fied where no guidelines are available. Conclusions: This study is the largest global survey performed to date on the clinical management of varicocele for male in- fertility. It demonstrates: 1) a wide disagreement in the approach to varicocele management, 2) large gaps in the clinical prac- tice guidelines from professional societies, and 3) the need for further studies on several aspects of varicocele management in infertile men.

Published
2022
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31. THE EFFECTS OF PURPLE SWEET POTATO (Ipomoea batatas L.) ETHANOL EXTRACT ON BLADDER UROTHELIAL LAYER AND SMOOTH MUSCLE THICKNESSES IN MENOPAUSAL FEMALE WISTAR RATS.

Author

Putra, Bismantara A., Santosa, Kadek Budi, Niryana, I. Wayan, Golden, Nyoman, Duarsa, Gede Wirya Kusuma, and Suryawisesa, Ida Bagus Made

Subjects
EXPERIMENTAL design, BLADDER, SMOOTH muscle, HORMONE therapy, ANIMAL experimentation, SWEET potatoes, RATS, T-test (Statistics), DESCRIPTIVE statistics, POSTMENOPAUSE, PLANT extracts, ETHANOL, MENOPAUSE, STATISTICAL sampling, DATA analysis software, PHYTOESTROGENS
Abstract

Postmenopausal women experience estrogen hormone deficiency, which can cause thinning of the smooth muscle and urothelial layer of the bladder, leading to lower urinary tract symptoms (LUTS). Hormone replacement therapy (HRT) has been the primary choice for addressing these problems. However, long-term prescription of HRT can result in several adverse effects, including a higher risk of breast cancer and cardiovascular diseases. Phytoestrogen, an estrogen-like compound derived from plants such as purple sweet potatoes (Ipomoea batatas L.), contains anthocyanin that could serve as a better alternative to estrogen replacement therapy. This study aimed to demonstrate the effects of phytoestrogens in purple sweet potatoes on the histomorphology of the bladder in menopausal female Wistar rats (Rattus norvegicus). This experimental study used a posttest-only control group design. A total of 36 Wistar rats undergoing ovariectomy were randomly assigned into two groups, with 18 samples in each group. The experimental group received the purple sweet potato ethanol extract orally, while the control group received a placebo. The structures of the smooth muscle and urothelial layer of the bladder were observed using a microscope. Data were analyzed using an independent t-test to compare bladder smooth muscle and urothelial layer thickness between groups, with a significance of p<0.05. A normality test was performed to determine the normal distribution of the data. Normally distributed data were assessed to find the mean and standard deviation (SD). Significant differences were found in the mean thickness of the smooth muscle and urothelial layer between both groups (p=0.00), with both being thicker in the experimental group. In conclusion, phytoestrogens in purple sweet potatoes can influence the histomorphology of the bladder. Ovariectomized female Wistar rats that received purple sweet potato ethanol extract exhibited thicker smooth muscle and urothelial layer of the bladder. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Post-Vasectomy Semen Analysis: Optimizing Laboratory Procedures and Test Interpretation through a Clinical Audit and Global Survey of Practices

Author

Agarwal, Ashok, primary, Gupta, Sajal, additional, Sharma, Rakesh K., additional, Finelli, Renata, additional, Kuroda, Shinnosuke, additional, Vij, Sarah C., additional, Boitrelle, Florence, additional, Kavoussi, Parviz, additional, Rambhatla, Amarnath, additional, Saleh, Ramadan, additional, Chung, Eric, additional, Mostafa, Taymour, additional, Zini, Armand, additional, Ko, Edmund, additional, Parekh, Neel, additional, Martinez, Marlon, additional, Arafa, Mohamed, additional, Tadros, Nicholas, additional, de la Rosette, Jean, additional, Le, Tan V., additional, Rajmil, Osvaldo, additional, Kandil, Hussein, additional, Blecher, Gideon, additional, Liguori, Giovanni, additional, Caroppo, Ettore, additional, Ho, Christopher C.K., additional, Altman, Andrew, additional, Bajic, Petar, additional, Goldfarb, David, additional, Gill, Bradley, additional, Zylbersztejn, Daniel Suslik, additional, Molina, Juan Manuel Corral, additional, Gava, Marcello M., additional, Cardoso, Joao Paulo Greco, additional, Kosgi, Raghavender, additional, Çeker, Gökhan, additional, Zilaitiene, Birute, additional, Pescatori, Edoardo, additional, Borges, Edson, additional, Duarsa, Gede Wirya Kusuma, additional, Pinggera, Germar-Michael, additional, Busetto, Gian Maria, additional, Balercia, Giancarlo, additional, Franco, Giorgio, additional, Çalik, Gökhan, additional, Sallam, Hassan N., additional, Park, Hyun Jun, additional, Ramsay, Jonathan, additional, Alvarez, Juan, additional, Khalafalla, Kareim, additional, Bowa, Kasonde, additional, Hakim, Lukman, additional, Simopoulou, Mara, additional, Rodriguez, Marcelo Gabriel, additional, Sabbaghian, Marjan, additional, Elbardisi, Haitham, additional, Timpano, Massimiliano, additional, Altan, Mesut, additional, Elkhouly, Mohamed, additional, Al-Marhoon, Mohamed S., additional, Sadighi Gilani, Mohammad Ali, additional, Soebadi, Mohammad Ayodhia, additional, Nasr-Esfahani, Mohammad Hossein, additional, Garrido, Nicolas, additional, Vogiatzi, Paraskevi, additional, Birowo, Ponco, additional, Patel, Premal, additional, Javed, Qaisar, additional, Ambar, Rafael F., additional, Adriansjah, Ricky, additional, AlSaid, Sami, additional, Micic, Sava, additional, Lewis, Sheena E., additional, Mutambirwa, Shingai, additional, Fukuhara, Shinichiro, additional, Parekattil, Sijo, additional, Ahn, Sun Tae, additional, Jindal, Sunil, additional, Takeshima, Teppei, additional, Puigvert, Ana, additional, Amano, Toshiyasu, additional, Barrett, Trenton, additional, Toprak, Tuncay, additional, Malhotra, Vineet, additional, Atmoko, Widi, additional, Yumura, Yasushi, additional, Morimoto, Yoshiharu, additional, Lima, Thiago Fernandes Negris, additional, Kunz, Yannic, additional, Kato, Yuki, additional, Umemoto, Yukihiro, additional, Colpi, Giovanni M., additional, Durairajanayagam, Damayanthi, additional, and Shah, Rupin, additional

Published
2022
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37. Risk Factors for Prostate Volume Progression After Prostate-Transurethral Resection

Author

Duarsa, Gede Wirya Kusuma, Dau, Daniel Oktavianus, Pramana, Ida Bagus Putra, Tirtayasa, Pande Made Wisnu, Yudiana, I Wayan, Santosa, Kadek Budi, Oka, Anak Agung Gde, Mahadewa, Tjokorda Gde Bagus, and Ryalino, Christopher

Subjects
TGF-β, PSA, TURP, age, Research and Reports in Urology, TNF-α, BPH, testosterone, urologic and male genital diseases, Original Research
Abstract

Gede Wirya Kusuma Duarsa,1 Daniel Oktavianus Dau,1 Ida Bagus Putra Pramana,1 Pande Made Wisnu Tirtayasa,1 I Wayan Yudiana,1 Kadek Budi Santosa,1 Anak Agung Gde Oka,1 Tjokorda Gde Bagus Mahadewa,1 Christopher Ryalino2 1Department of Surgery, Faculty of Medicine, Udayana University, Bali, Indonesia; 2Department of Anesthesiology, Faculty of Medicine, Udayana University, Bali, IndonesiaCorrespondence: Gede Wirya Kusuma DuarsaDepartment of Surgery, Faculty of Medicine, Udayana University, Bali, IndonesiaEmail gwkduarsa@gmail.comBackground: Many factors could contribute to the cases of residual benign prostate hypertrophy (BPH) volume after transurethral resection of the prostate (TURP), such as age, obesity, testosterone level, and inflammation. The goal of this study was to determine the risk of tumor necrosis factor-α (TNF-α), transforming growth factor-β (TGF-β) in prostate tissue, serum prostate-specific antigen (PSA), serum testosterone, and age in promoting prostate volume progression after TURP.Patients and Methods: This was a prospective cohort study on 83 BPH patients who underwent TURP at five hospitals in Bali, Indonesia. Trans-rectal ultrasonography (TRUS) was carried out to examine the prostate’s size. Three years after, we redo the TRUS examination to collect the data of the latest prostate size. TNF-α, TGF-β, serum PSA, testosterone, and age were registered for analysis. We used Pearson’s and Spearman’s correlation tests and multivariate analytic linear regression test (coefficient β) by SPSS 13.0 software.Results: Age, testosterone, PSA, TNF-α, TGF-β were positively correlated to prostate’s volume progression. The prostate volume was strongly correlated with age (r= 0.749, p < 0.001), PSA level (r=0.896, p < 0.001), testosterone level (r=0.818, p < 0.001), and TGF-β (r=0.609, p < 0.001). The TNF-α level has a weak correlation to prostate’s volume progression (r=0.392, p < 0.001).Conclusion: TNF-α, TGF-β, PSA, testosterone, and age were significant as the risk factors in promoting the prostate volume progression after TURP.Keywords: age, testosterone, PSA, TNF-α, TGF-β, BPH, TURP

Published
2020

44. Correlation of total ischemic time to creatinine serum level and resistive index value in kidney transplant

Author

Novianti, Putu Astri, primary, Duarsa, Gede Wirya Kusuma, additional, Aditya, Gede Andi, additional, Oka, Anak Agung Gde, additional, Santosa, Kadek Budi, additional, Yudiana, I Wayan, additional, Tirtayasa, Pande Made Wisnu, additional, Pramana, Ida Bagus Putra, additional, Kandarini, Yenny, additional, Sudana, Wayan, additional, Sidartha, Djodi, additional, and Widiana, Raka, additional

Published
2020
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45. Perbedaan proporsi antara lokasi batu,skin-to-stone distance, kekerasan batu, ukuran batu pada computed tomography stonografi serta index massa tubuh dan fungsi ginjal dengan angka bebas batu pasca extracorporeal shock wave lithotripsy pada pasien batu gi

Author

Uneputty, Yulandri Franeldo, primary, Duarsa, Gede Wirya Kusuma, additional, Yudiana, I Wayan Yudiana, additional, Santosa, I Kadek Budi, additional, Tirtayasa, Pande Made Wisnu, additional, Pramana, Ida Bagus Putra, additional, Mahadewa, Tjok G.B Mahadewa, additional, and Oka, A.A. Gde, additional

Published
2020
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48. The Comparable Results of Minimally Invasive Therapy versus Primary Anastomosis in the Management of Partial Posterior Urethral Stricture

Author

Duarsa, Gede Wirya Kusuma, primary, Subnafeu, Rheny, additional, Oka, Anak Agung Gde, additional, Santosa, I Kadek Budi, additional, Yudiana, I Wayan, additional, Tirtayasa, Pande Made Wisnu, additional, Pramana, Ida Bagus Putra, additional, Mahadewa, Tjokorda Gede Bagus, additional, and Ryalino, Christopher, additional

Published
2020
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