Shehatta, Omar Mohamed, Osman, Ahmed Luay, Elsayed, Walid Shaaban, Reddy, Sesha, Dsouza, Jovita, Abdelmagyd, Hossam, and Shadroch, Devapriya Finney
Streptococcus Viridans can cause diseases of the heart valves known as Infective Endocarditis, in addition to causing periodontal disease. As an adjunct to mechanical plaque control, mouthwashes aid in the control and prevention of dental plaque biofilm. The aim of this study was to find out whether there is any difference in the antimicrobial efficacy between chlorhexidine and hyaluronic acid on the CFUs of Streptococcus Viridans. Commercially available Streptococcus Viridans isolates obtained from the American Type Culture Collection (ATCC 12392, USA) were used in this study. 0.1 mL volume of the prepared bacterial suspension was added to 3 serial dilutions (100%, 50% and 25% concentration) of Chlorhexidine mouthwash (CHX) and Hyaluronic acid mouthwash (HA) including NaCl (0.9%) which was the control. Following the incubation (for 0.5, 1, 1.5 and 5 min, at 37 °C). Chlorhexidine at 0.2% concentration showed significant reductions of CFUs/ml; (1,859 at 30 seconds, 1,105 at 1 minute, 936 at 1.5 minutes and 234 at 5 minutes) as compared to the control (CFU >106). Hyaluronic acid did not have an effect on the number of colonies with >106 CFUs/ml in all concentrations. Hyaluronic acid did not exhibit any antimicrobial effect on Streptococcus Viridans. [ABSTRACT FROM AUTHOR]