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'A wonderfully accessible exploration of one of the most complex problems of our age'TELEGRAPH'Magic Pill will help you think more clearly about eating, dieting, health and mental health, even if you never touch Ozempic'JONATHAN HAIDTThe bestselling author of Lost Connections and Stolen Focus takes a revelatory look at the new drugs transforming weight loss as we know it – sharing his personal experience on Ozempic and examining our ability to heal society's dysfunctional relationship with food, weight and our bodies. In January 2023, Johann Hari started to inject himself once a week with Ozempic, one of the new drugs that produces significant weight loss. He wasn't alone – some predictions suggest that in a few years, one in four of the British population will be taking these drugs. While around 80 per cent of diets fail, someone taking one of the new drugs is likely to lose up to a quarter of their body weight in six months. To the drugs'defenders, this is a moment of liberation from a condition that massively increases your chances of diabetes, cancer and an early death. Still, Hari was wildly conflicted. Can these drugs really be as good as they sound? Are they a magic solution – or a magical illusion? Finding the answer to this high-stakes question led him on a journey from Iceland to Minneapolis to Tokyo, and to interview the leading experts in the world on these issues. He found that along with the drugs'massive benefits come twelve significant potential risks. He also learned that these drugs radically challenge what we think we know about shame, willpower and healing. These drugs are about to change our world, for better and for worse. Everybody needs to understand how they work – scientifically, emotionally and culturally. Magic Pill is an essential guide to the revolution that has already begun – and which one leading expert argues could be as transformative as the invention of the smartphone.'A brilliant synthesis of so much important information. Really important, and very necessary'STEPHEN FRY'Compassionate, wise and mind-expanding... A must read'PHILIPPA PERRY

Including new drugs for weight loss, heart failure, anxiety, and postpartum depression. OZEMPIC | WEGOVY | ENTRESTRO | AND MORE! Hale's Medications & Mothers'Milk is the ultimate resource for safe medication practices during breastfeeding. This meticulously updated edition offers the most current, evidence-based information available, maintaining its reputation as the definitive standard for medication safety in lactation. Written by world-renowned clinical pharmacologists, the detailed manual helps lactation consultants, pharmacists, and healthcare providers who work with women and children weigh the relative risks associated with commonly used medications, drawing from the latest evidence-based studies. Structured for quick and efficient use, this guide features Dr. Thomas W. Hale's renowned Lactation Risk Categories (LRC), which provide essential insight, listing safe medication alternatives that can be used now or in the future. The manual is intuitively organized to highlight key points, offer practical tips, and present easy-to-understand diagrams, common abbreviations, and concise information for evaluating infant health. This indispensable resource helps healthcare professionals to ensure the safety and well-being of both mother and infant. Embrace the peace of mind that comes with having reliable, expert-vetted knowledge at your fingertips. To ensure you always have the most current information, consider our online or mobile app subscription! Visit halesmeds.com to get started today. New to the 2025-2026 Edition: 66 new drugs 10 drugs with FDA updates 575 updated medications (formerly medications updated with new information) 84 existing drugs with updated LRCs Key Features: Delivers current, evidence-based information on 1,300 drugs, diseases, vaccines, and syndromes in alphabetical order Provides critical updates on weight loss drugs such as Wegovy and Ozempic, heart failure drugs such as Entresto, medications for anxiety, postpartum depression, and much more Incorporates updates to Dr. Hale's world-renowned Lactation Risk Categories (LRC) Discusses adult concerns, adult dose, pediatric concerns, infant monitoring, and drug alternatives

Adverse events in patients caused by medical management are a serious and grossly underreported public health problem. One patient in ten entering hospital will suffer an adverse event of impairment, disability or death. This book is a major comprehensive examination of the incidence and causes of adverse events. Using data obtained from hospitals within the United Kingdom, United States and other developed countries, it examines the risk factors leading to errors, the human and financial costs, and the scope to reduce errors. In particular, it focuses on the need for a critical reappraisal of undergraduate teaching and clinical tuition. All healthcare professionals throughout primary and secondary care, including clinicians, managers and policy makers, and patient and carer groups, can benefit from reading this book. It identifies possible solutions and how adverse events and medication errors can be reduced, resulting in improved patient care.

The science of drug safety and pharmacovigilance has rapidly evolved in the 21st century. The knowledge and principles it contains are of increasing importance in clinical and practice settings. The aim of this book is to deal with the gap in knowledge about pharmacovigilance and drug safety, including the application of pharmacovigilance knowledge to individual patient cases in clinical practice. A holistic approach is taken with each chapter written from the perspective of a practitioner, industry personnel, researcher, or regulator, creating a synergy between drug safety, pharmacovigilance, and clinical practice. Chapters offer key material on adverse drug reactions, medication errors, prescribing safety, pharmacovigilance as well as data sources used in drug safety and pharmacovigilance. Each chapter is structured as a self-contained learning resource, with learning objectives, and worked cases. The book is suitable for undergraduate healthcare professions, postgraduate students, researchers, clinical practitioners – including those with prescribing responsibilities. It will also be useful for professionals moving from a clinical practice role to a specialist pharmacovigilance role. For those already in a pharmacovigilance role, the book offers insight into the theory and practice of drug safety and pharmacovigilance in clinical settings.

Terence Young exposes the pharmaceutical industry secrets and cultural myths that thwart our safe use of prescription drugs.… Everyone should read it before their next visit to a doctor. — DR. NANCY OLIVIERI, MD, physician and professor When it comes to drug safety, Big Pharma holds all the power, and it's time for patients to take it back.Tens of millions of patients in North America take prescription drugs, but the safety of these drugs is often based on medical myths. We are led to believe that if a medication isn't safe, the government would never allow it on the market and that doctors would never prescribe a drug that isn't proven effective. Who controls these narratives? And do they always have the best interests of patients in mind?In an in-depth study of the enormous influence the pharmaceutical industry has over our health, drug safety advocate Terence Young explores how those with the most to gain financially are also those who wield all the power in health care — and withhold the knowledge that is critical to the safety of patients.Forbidden Knowledge reveals the truth you need to know about prescription drugs and what to do about it. It will empower you to partner with your doctor to talk openly and plainly about medications to help avoid serious adverse drug reactions. This is your survival guide to Big Pharma.

The book follows a HD as it transits through a healthcare facility, addressing core elements of the USP chapter, to answer major questions healthcare systems may have when implementing the standards. The Q&A approach of the chapter provides a comprehensive overview and explanation of the requirements of USP as well as: Hazardous Drug Risk Assessment Form Sample Form: Employee Acknowledgement of Hazardous Drug Risk List of Policies Required and Recommended in USP List of new and updated questions since the first edition Sample “Action Plan” for Compliance with USP

Arzneimittel-Nebenwirkungen als solche zu erkennen, dem ursächlichen Medikament zuzuordnen und wenn nötig daraufhin richtig zu reagieren, sind essenzielle Bestandteile des pharmazeutischen Medikationsmanagements – sei es in der Apotheke oder in der Klinik. Das frühzeitige Erkennen und Handeln ist hierbei nicht nur für die Adhärenz und den Therapie-Erfolg entscheidend, sondern kann unnötige Wiedereinweisungen verhindern, Gesundheitskosten reduzieren und – am wichtigsten – die Patientensicherheit und Überlebenswahrscheinlichkeit erhöhen. Nebenwirkungen werden von Patientinnen und Patienten zumeist als organspezifische Symptome geschildert. Da jedoch gerade ältere oder multimorbide Menschen in der Regel eine Vielzahl an Arzneimitteln einnehmen, kann sich eine Analyse als sehr komplex erweisen. In diesem Buch sind die Arzneimittel-Nebenwirkungen strukturiert nach Organen gegliedert, was die ursächliche Zuordnung eines geschilderten Symptoms im polypharmazeutischen Umfeld wesentlich erleichtert. Mithilfe von Fallbeispielen, Praxistipps und zahlreichen Tabellen werden die Inhalte anschaulich vermittelt und praktische Handlungsempfehlungen gegeben.

Adults ages 65+: Your medication could be the reason for your new medical condition; read this eye-opening guide to become an expert on what medications you take!We have a medication problem in America. It is marked not only by excessive use of medications, but by errors in how they are prescribed, monitored, and taken. An estimated nineteen million adults age sixty-five and older take five or more medications daily. These individuals and family caregivers know the frustrations of lengthy medication lists, high drug costs, and frequent questions about the need and value of those medications. All too often, an unrecognized adverse drug effect is mistaken for a new medical condition, or worse, a symptom of getting older. But who stops to question the medications?Maybe It's Your Medicationstackles these problems by providing information, insider tips, and strategies that empower patients and caregivers to have important conversations about their prescription and nonprescription drugs. This book addresses the questions consumers want to ask about their medications and brings to light other questions they should be asking but may not know how. It is everyone's go-to guide on how to use medications safely on the journey to healthy aging. Dr. Hedva Barenholtz Levy, PharmD, is a geriatric specialist and founder of a unique senior care practice of over 25 years working with patients in their homes. She is an educator and leader in geriatric pharmacy and a dual board-certified specialist. Dr. Levy applies her decades of experience to guide the reader in how to become an active participant on their healthcare team and prevent unintended errors and medication-related problems.

Le manuel pour comprendre toute l'UE 2.11 Pharmacologie et thérapeutiques. Divisé en 15 chapitres, ce manuel complet et didactique vous aidera à comprendre et assimiler le cours de pharmacologie et ainsi réussir au mieux les trois évaluations de l'UE 2.11 (aux semestres 1, 3 et 5). Chaque chapitre comprend : - l'essentiel du cours, ponctué de plus de 150 illustrations, d'encadrés « En pratique » pour répondre aux exigences du quotidien et de « Zoom sur... » pour rappeler les cadres théoriques ou légaux à propos des médicaments ; - des situations professionnelles infirmières avec des études de cas pour allier raisonnement et pratique de soins ; - des exercices d'auto-évaluation sous la forme de QCM et de QROC. Ce manuel rassemble ainsi toutes les connaissances à maîtriser pour contribuer à la réussite des étudiants en IFSI.

Globally, tuberculosis (TB) is one of the top 10 causes of death, the leading cause of death from a single infectious agent, and the leading cause of death among subjects living with the human immunodeficiency virus. Since it practically affects all the organs and tissues of the body, it is of vital importance that all health personnel know the fundamental principles for the treatment of this disease and the complications that might arise from the use of multidrug treatment regimens.The treatment of TB requires the use of multiple drugs for long periods. However, most patients will experience some difficulty tolerating them at some point. This book is a practical clinical guide aimed at health personnel who need to treat patients with tuberculosis. It includes a detailed description of the adverse effects of drugs on the different systems of the body and the therapeutic strategies for their management.

Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.

Essential for ob/gyn physicians, primary care physicians, and any health care provider working with pregnant or postpartum women, Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk, 12th Edition, puts must-know information at your fingertips in seconds. An easy A-to-Z format lists more than 1,400 of the most commonly prescribed drugs taken during pregnancy and lactation, with detailed monographs designed to provide the most essential information on possible effects on the mother, embryo, fetus, and nursing infant.

This fourth volume in an exciting and detailed series on contact allergens and drug allergy provides monographs of all 507 systemic drugs which have caused delayed-type cutaneous drug hypersensitivity reactions and/or occupational allergic contact dermatitis. The monographs present: Identification section; Occupational allergic contact dermatitis; and Cutaneous adverse drug reactions from systemic drugs caused by type IV (delayed-type) hypersensitivity, as shown by positive patch tests (e.g. maculopapular eruption, acute generalized exanthematous pustulosis [AGEP], symmetrical drug-related intertriginous and flexural exanthema [SDRIFE], fixed drug eruption, drug reaction with eosinophilia and systemic symptoms [DRESS], and photosensitivity). Separate chapters present an overview of the spectrum of allergic cutaneous drug reactions, diagnostic tests, immediate contact reactions (contact urticaria), and systemic drugs that have acquired delayed-type hypersensitivity only by cross-reactivity.Key Features: Presents monographs of all known systemic drugs which have caused delayed allergic cutaneous drug reactions and/or occupational allergic contact dermatitis Provides an extensive literature review of relevant topics of allergenic systemic drugs, part of which is hard or impossible to find in database searches Identifies IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing Presents immediate contact reactions (contact urticaria) from systemics drugs and delayed-type hypersensitivity in drugs caused only by cross-reactivity Covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy

This practical handbook provides detailed guidelines on prescribing drugs in all classes and for a wide variety of diseases and disorders during pregnancy, with numerous boxes and tables to assist understanding. CONTENTS: Introduction to Drugs in Pregnancy • Antimicrobials during Pregnancy: Bacterial, Viral, Fungal, and Parasitic Indications • Cardiovascular Drugs during Pregnancy • Endocrine Disorders, Contraception, and Hormone Therapy during Pregnancy: Embryotoxic versus Fetal Effects • Antiasthma Agents during Pregnancy • Anesthetic Agents and Surgery during Pregnancy • Antineoplastic Drugs during Pregnancy • Analgesics during Pregnancy • Anticonvulsant Drugs during Pregnancy • Psychotropic Use during Pregnancy • Antihistamines, Decongestants, and Expectorants during Pregnancy • Nutritional and Dietary Supplementation during Pregnancy • Use of Dermatologics during Pregnancy • Drug Overdoses during Pregnancy • Miscellaneous Drugs during Pregnancy: Tocolytics, Immunosuppressants, and Biologic Therapeutics • Substance Abuse during Pregnancy • Online Support Material

Litt's Drug Eruption & Reaction Manual is a succinct clinical reference derived from Litt's Drug Eruption & Reaction Database (www.drugeruptiondata.com), which currently holds over 1800 drug profiles with over 70,000 documented drug reactions, as evidenced by well over 150,500 references on PubMed. Internationally relied upon by medical practitioners for its unparalleled focus on adverse effects and cutaneous reactions, this 28th edition has been comprehensively updated with the essential information for an informed clinical decision. A one-year access to the associated database is now included on proof of purchase in 2022 of a new copy of the 2022 print edition. • Provides documentation of adverse reactions to the 1500 most consulted drug and herbal profiles • Gives clinicians managing patients with many different medications a route to making an informed decision about problematic reactions • Offers clinicians a one-stop reference for the essential information about a drug

This book provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance. It will be of value for all dental and medical practitioners who encounter these complications in their clinical practice.

Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 43, first published in 1977, and continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered in this new release include Central Nervous System Stimulants and Drugs that Suppress Appetite, Antidepressants, Lithium, Drugs of Abuse, Hypnotics and Sedatives, Antipsychotic Drugs, Antiepileptics, Opioid Analgesics and Narcotic Antagonists, Anti-Inflammatory and Antipyretic Analgesics and Drugs Used in Gout, and much more. - Provides a critical yearly survey of the new data and trends regarding the side effects of drugs - Authored and reviewed by worldwide pioneers in the clinical and practice sciences - Presents an essential clinical guide on the side effects of drugs for practitioners and healthcare professionals alike

This book is a first-of-its kind reference that systematically organizes and describes the adverse effects of drugs on the nervous system. Drug safety is recognized as an important aspect of pharmaceutical companies as well as practice of medicine. Chapters include case reports of adverse effects of drugs that are published as well as reported to drug manufacturers. The book scope is broad as it covers lack of efficacy, drug resistance, drug-disease and drug-drug interactions. This information is used to improve the use of drugs as well as to design better and safer drugs for the future, and is relevant to personalized medicine in trying to match the right drugs to the patients.Drug-induced Neurological Disorders offers a unique approach to this important topic by integrating clinical neurology with pharmacology with a focus on effects of drugs on the nervous system including those used for the treatment of neurological disorders as well systemic diseases. Many adverse effects involve multiple systems of the body and the syndromes with predominant effect on the nervous system are included in this book.

This first-of-its-kind handbook offers crucial information on the safety of drugs taken during pregnancy. It covers an exhaustive list of common and less common drugs and provides for each drug the FDA letter categorization and newly approved “Pregnancy and Lactation Labeling Rule (PLLR)” systems for rating drug risks in pregnancy, imposed by the U.S. Food and Drug Administration (FDA). Drugs in Pregnancy: A Handbook for Pharmacists and Physicians covers the pregnancy ramifications of using anti-infective, cardiovascular, hematologic, dermatologic drugs and drugs affecting the endocrine, central, autonomic, gastrointestinal, musculoskeletal systems in addition to herbs, vitamins and dietary supplements. To enable the reader to develop well-informed knowledge about a drug safety profile during pregnancy, three sections of data have been provided for each drug: FDA Category, Risk Summary, and Further Reading.

Written by global experts in the field of chemical- and drug-related ocular problems, Drug-Induced Ocular Side Effects, 8th Edition, provides need-to-know information on all aspects of ocular toxicology in one concise reference. This best-selling, user-friendly resource features a templated format, numerous full-color illustrations, and sweeping content updates throughout – all designed to eliminate uncertainty and ensure accurate diagnosis and treatment guidance. - Provides comprehensive coverage of drugs'generic and trade names, primary uses, ocular and systemic side effects, and clinical significance. - Features a unique side effect index, a new concise paperback format for portability, and clinical photos of ocular symptoms of adverse drug reactions. - Covers dozens of new drugs used in the U.S. and internationally, as well as extensive updates to drug registry information to ensure access to the latest data. - Includes expanded sections on how to follow patients with visual adverse drug reactions to chloroquine, hydroxychloroquine, isotretinoin, ethambutol, and more. Guidelines can be copied to use as patient handouts. - Offers extensive discussions of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics. - Provides the WHO classification system to help you determine whether a particular side effect is certain, probable, or likely to occur. - Ideal for ophthalmologists, optometrists, and busy clinicians in primary care, emergency medicine, and more – anyone who needs quick, on-the-spot consultation on ocular toxicology. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Drug Safety in Developing Countries: Achievements and Challenges provides comprehensive information on drug safety issues in developing countries. Drug safety practice in developing countries varies substantially from country to country. This can lead to a rise in adverse reactions and a lack of reporting can exasperate the situation and lead to negative medical outcomes. This book documents the history and development of drug safety systems, pharmacovigilance centers and activities in developing countries, describing their current situation and achievements of drug safety practice. Further, using extensive case studies, the book addresses the challenges of drug safety in developing countries. - Provides a single resource for educators, professionals, researchers, policymakers, organizations and other readers with comprehensive information and a guide on drug safety related issues - Describes current achievements of drug safety practice in developing countries - Addresses the challenges of drug safety in developing countries - Provides recommendations, including practical ways to implement strategies and overcome challenges surrounding drug safety

Globalization is rapidly changing lives and industries around the world. Drug development, authorization, and regulatory supervision have become international endeavors, with most medicines becoming global commodities. Drug companies utilize global supply chains that often include facilities in countries with inconsistent regulations from those of the United States, perform pivotal trials in multiple countries to support registration submissions in various jurisdictions, and subsequently market their medicines throughout most of the world. These companies operate across borders and require individual national regulators to ensure that drugs authorized for use in their countries are safe and effective, and appropriate for their health care system and their population. This process involves significant resources and often duplicative work. It is important to consider how this process can be improved in order to better allocate resources, time, and efforts to improve public health. Regulating Medicines in a Globalized World: The Need for Increased Reliance Among Regulators considers the role of mutual recognition and other reliance activities among regulators in contributing to enhancing public health. This report identifies opportunities for leveraging reliance activities more broadly in order to potentially impact public health globally. Key topics in this report include the job of medicines regulators in today's world, what policy makers need to know about today's regulatory environment, stakeholder views of recognition and reliance, as well as removing impediments and facilitating action for greater recognition and reliance among regulatory authorities.