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184 results on '"Drosos, Georgios I."'

28. Local Antibiotic Delivery Systems in the Surgical Treatment of Diabetic Foot Osteomyelitis: Again, No Benefit?

Author

Chatzipapas, Christos, Kougioumtzis, Ioannis E., Karaglani, Makrina, Panagopoulos, Periklis, Panopoulou, Maria, Papazoglou, Dimitrios, Drosos, Georgios I., and Papanas, Nikolaos

Abstract

This retrospective study aimed to compare the outcomes and healing parameters of 3 groups of surgical treatment combined with and without local antibiotic administration in diabetic foot osteomyelitis (DFO). Overall, 25 patients with DFO who met the criteria were included in the study. Surgical debridement was used with systemic antibiotic administration alone (group A; n = 8) or combined with local application of antibiotic-loaded polymethylmethacrylate beads (group B; n = 9) or antibiotic-loaded hydroxyapatite and calcium sulfate beads (group C; n = 8). In total, 87.5% patients in group A, 100% in group B, and 87.5% in group C healed (P =.543). Median time to healing was 17 weeks in group A, 18 weeks in group B, and 19 weeks in group C (P =.094). One patient (12.5%) in group A was amputated. DFO recurrence rate was 12.5% in group A and 12.5% in group C (P =.543). Median hospitalization was 9 days in group A, 8 days in group B, and 9 days in group C (P =.081). In conclusion, adjunctive local antibiotic therapy was not shown to improve outcomes in surgically treated DFO. [ABSTRACT FROM AUTHOR]

Published
2022
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29. Perioperative Blood Management Strategies for Patients Undergoing Total Hip Arthroplasty: Where Do We Currently Stand on This Matter?

Author

Vrontis, Konstantinos, Tsinaslanidis, Georgios, Drosos, Georgios I., and Tzatzairis, Themistoklis

Subjects
Current Concepts Review
Abstract

Total hip replacement (THR) has proved to be a reliable treatment for the end stage of hip osteoarthritis. It is a common orthopaedic procedure with excellent results, but is associated with significant blood loss and high rates of allogeneic blood transfusion (ABT). The potential complications and adverse events after ABT, combined with the ongoing research, have resulted in multimodel, multidisciplinary blood management strategies adoption, aiming to reduce the blood loss and transfusion rates. Many reviews and meta-analyses have tried to demonstrate the best blood management strategies. The purpose of this study is to review any evidence-based blood conserving technique, dividing them in three stages: preoperative, intraoperative and postoperative.

Published
2020

33. The Effect of Strontium Ranelate on Fracture Healing: An Animal Study

Author

Koukou, Ourania I., primary, Pappas, Lampros D., additional, Chloropoulou, Pelagia, additional, Kouroupi, Maria A., additional, Koukos, Konstantinos I., additional, Karpathiou, Georgia, additional, Galanos, Antonios A., additional, Drosos, Georgios I., additional, Magnisalis, Evaggelos, additional, Giatromanolaki, Alexandra N., additional, and Verettas, Dionysios Alexandros, additional

Published
2020
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37. The Effect of Strontium Ranelate on Fracture Healing: An Animal Study

Author

Koukou, Ourania I. Pappas, Lampros D. Chloropoulou, Pelagia and Kouroupi, Maria A. Koukos, Konstantinos I. Karpathiou, Georgia and Galanos, Antonios A. Drosos, Georgios I. Magnisalis, Evaggelos Giatromanolaki, Alexandra N. Verettas, Dionysios Alexandros

Abstract

Background. Strontium ranelate (StR) is an antiosteoporotic agent previously utilized for the enhancement of fracture union. We investigated the effects of StR on fracture healing using a rabbit model. Methods. Forty adult female rabbits were included in the study and were divided in 2 equal groups, according to StR treatment or untreated controls. All animals were subjected to osteotomy of the ulna, while the contralateral ulna remained intact and served as a control for the biomechanical assessment of fracture healing. Animals in the study group received 600 mg/kg/day of StR orally. All animals received ordinary food. At 2 and 4 weeks, all animals were euthanatized and the osteotomy sites were evaluated for healing through radiological, biomechanical, and histopathological studies. Results. The treatment group presented statistically significant higher callus diameter, total callus area, percentage of fibrous tissue (p

Published
2020

41. Short stems in total hip replacement: evidence on primary stability according to the stem type.

Author

Drosos, Georgios I. and Touzopoulos, Panagiotis

Subjects
*BIOMECHANICS, *PROSTHETICS, *COMPLICATIONS of prosthesis, *TOTAL hip replacement, *SYSTEMATIC reviews, *TREATMENT effectiveness
Abstract

Background: As the prevalence of total hip replacement is increasing in younger patients, less invasive implants (short stems) are becoming more favourable. However, despite the advantages of these stems, clinical results with a follow-up of more than 10 years are limited to a very few stem designs. There has been an increase in publications recently – mechanical and clinical studies – concerning the primary stability of short stems. Primary stem stability is an important factor as it reflects final stem stabilisation and is related to the clinical results of the prosthesis. Method: We conducted a systematic review of the literature to retrieve evidence concerning primary implant stability in short stems – as expressed by implant micromotion and stem subsidence – according to our previously proposed short-stem classification. Results: Mechanical in vitro studies on stem micromotion are very few and limited to type 2 "partial collum" short stems. The results are comparable to those of stems with a known long-term excellent clinical course. Clinical results concerning stem migration patterns are also limited to some of the commercially available short stems. Although comparative studies are very few, the results for most of the short stems are similar to those of standard stems. Conclusion: There are promising results concerning biomechanical studies of the initial micromotion of short stems, as well as clinical results of stem migration patterns. Long-term clinical studies are needed in order to confirm these findings. The existing literature concerns very few of the many commercially available implants. [ABSTRACT FROM AUTHOR]

Published
2019
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