1. PERFORMANCE OF TOTAL PANCREATECTOMY FOR PANCREATIC MALIGNANCIES.
- Author
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Dronov AI, Zemskov SV, and Kryuchina EA
- Subjects
- Adenocarcinoma, Mucinous metabolism, Adenocarcinoma, Mucinous mortality, Adenocarcinoma, Mucinous pathology, Adenocarcinoma, Papillary metabolism, Adenocarcinoma, Papillary mortality, Adenocarcinoma, Papillary pathology, Aged, Complex Regional Pain Syndromes diagnosis, Complex Regional Pain Syndromes etiology, Complex Regional Pain Syndromes mortality, Complex Regional Pain Syndromes pathology, Exocrine Pancreatic Insufficiency diagnosis, Exocrine Pancreatic Insufficiency etiology, Exocrine Pancreatic Insufficiency mortality, Exocrine Pancreatic Insufficiency pathology, Female, Humans, Jaundice, Obstructive diagnosis, Jaundice, Obstructive etiology, Jaundice, Obstructive mortality, Jaundice, Obstructive pathology, Male, Middle Aged, Neoplasm Staging, Pancreas metabolism, Pancreas pathology, Pancreatic Neoplasms metabolism, Pancreatic Neoplasms mortality, Pancreatic Neoplasms pathology, Postoperative Complications diagnosis, Postoperative Complications mortality, Postoperative Complications pathology, Quality of Life, Retrospective Studies, Survival Analysis, Ukraine, Adenocarcinoma, Mucinous surgery, Adenocarcinoma, Papillary surgery, Pancreas surgery, Pancreatectomy methods, Pancreatic Neoplasms surgery
- Abstract
Lethality, morbidity, survival indices and metabolic consequences of total pancreatec' tomy (TP), performed in patients, suffering pancreatic tumors, were analyzed. There were retrospectively analyzed 35 TP оperations, including 5— urgent, 30 — elective, performed in a single center. General lethality have constituted 20% (7 patients died), and after elective ТP — 6.7% (2 died). Complications rate after elective TP have consti' tuted 40%; survival mediana—18 mo; indices of a 3—year survival — 40%, and a 5— year one — 13.3%. Most frequently revealed metabolic changes after ТP — pancreatic exocrine insufficiency, pancreatogenic diabetes, changes in a lipid metabolism in hepatocytes. Our experience witnesses expediency of ТP introduction into surgical practice in specialized centers of Ukraine with results, which are matching a worldwide.
- Published
- 2016