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2. Antivirals and Male Reproduction

Author

Drobnis, Erma Z., Nangia, Ajay K., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, Drobnis, Erma Z., and Nangia, Ajay K.

Published
2017
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3. Pain Medications and Male Reproduction

Author

Drobnis, Erma Z., Nangia, Ajay K., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, Drobnis, Erma Z., and Nangia, Ajay K.

Published
2017
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6. Miscellaneous Drugs and Male Reproduction

Author

Drobnis, Erma Z., Nangia, Ajay K., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, Drobnis, Erma Z., and Nangia, Ajay K.

Published
2017
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7. Immunosuppressants and Male Reproduction

Author

Drobnis, Erma Z., Nangia, Ajay K., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, Drobnis, Erma Z., and Nangia, Ajay K.

Published
2017
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8. Psychotropics and Male Reproduction

Author

Drobnis, Erma Z., Nangia, Ajay K., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, Drobnis, Erma Z., and Nangia, Ajay K.

Published
2017
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11. Exogenous Androgens and Male Reproduction

Author

Drobnis, Erma Z., Nangia, Ajay K., COHEN, IRUN R., Series editor, LAJTHA, ABEL, Series editor, LAMBRIS, JOHN D., Series editor, PAOLETTI, RODOLFO, Series editor, REZAEI, NIMA, Series editor, Drobnis, Erma Z., and Nangia, Ajay K.

Published
2017
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13. Environmental exposure to di-2-ethylhexyl phthalate is associated with low interest in sexual activity in premenopausal women

Author

Barrett, Emily S, Parlett, Lauren E, Wang, Christina, Drobnis, Erma Z, Redmon, J Bruce, and Swan, Shanna H

Subjects
Reproductive Medicine, Biomedical and Clinical Sciences, Prevention, Pediatric, Estrogen, Clinical Research, Contraception/Reproduction, 2.1 Biological and endogenous factors, Aetiology, Reproductive health and childbirth, Good Health and Well Being, Adult, Cohort Studies, Diethylhexyl Phthalate, Environmental Exposure, Female, Humans, Libido, Phthalic Acids, Pregnancy, Pregnancy Complications, Premenopause, Prospective Studies, Reproduction, Sexual Behavior, Sexual Dysfunction, Physiological, Young Adult, Phthalates, Endocrine disruptors, Environmental chemicals, Sexual interest, Sexual dysfunction, Biological Sciences, Medical and Health Sciences, Behavioral Science & Comparative Psychology, Biological sciences, Biomedical and clinical sciences, Psychology
Abstract

Phthalates, a ubiquitous class of environmental chemicals, may interfere with typical reproductive hormone production both in utero and in adulthood. Although they are best known as anti-androgens, increasingly, evidence suggests that phthalates, particularly di-2-ethylhexyl phthalate (DEHP), may also suppress estrogen production. Given that both androgens and estrogens are essential for sexual function, particularly sexual interest, it is plausible that adult exposure to phthalates alters sexual function. To this end, we used data from 360 women participating in a pregnancy cohort study (the Study for Future Families) to examine whether urinary phthalate metabolite concentrations were associated with two dimensions of self-reported sexual dysfunction in the months prior to conception: lack of sexual interest and vaginal dryness. Women in the highest quartile of urinary concentrations of mono-2-ethyl-5-hydroxyhexyl phthalate, a DEHP metabolite, had 2.58 (95% CI 1.33, 5.00) times the adjusted odds of reporting that they almost always or often lacked interest in sexual activity, and results were similar for mono-2-ethyl-5-oxohexyl phthalate (aOR: 2.56, 95% CI 1.32, 4.95), another DEHP metabolite. Self-reported vaginal dryness was not associated with any phthalate metabolite concentration. This study is novel in its focus on sexual function in relation to environmentally relevant (rather than occupational) exposure to phthalates in adult women and these preliminary findings merit replication in a large, prospective study. Better understanding how adult exposure to phthalates may affect reproductive health, including sexual function, is of public health interest given that virtually all Westerners are exposed to phthalates.

Published
2014

22. List of Contributors

Author

Ahmad, Gulfam, primary, Alom, Manaf, additional, Alshahrani, Saad, additional, Alzweri, Laith, additional, Atala, Anthony, additional, Aubuchon, Mira, additional, Ayaz, Ahmet, additional, Badr, Fouad M., additional, Bakare, Tolulope O., additional, Bartolome, Alma R., additional, Bhattacharjee, Rudrarup, additional, Bishop, Colin, additional, Bivalacqua, Trinity, additional, Burnett, Arthur L., additional, Collica, Sarah, additional, Da Ros, Carlos T., additional, Dada, Rima, additional, DeLay, Kenneth, additional, Diao, Linley, additional, Dimitriadis, Fotios, additional, Drobnis, Erma Z., additional, El-Habit, Ola, additional, Evenson, Donald P., additional, Gabrielson, Andrew T., additional, Ghali, Fady, additional, Ghirelli-Filho, Milton, additional, Glina, Sidney, additional, Graziottin, Túlio M., additional, Gupta, Narmada P., additional, Gur, Serap, additional, Hallak, Jorge, additional, Haney, Nora M., additional, Harnisch, Brooke A., additional, Heidenberg, Daniel J., additional, Hellstrom, Wayne J.G., additional, Henkel, Ralf, additional, Hernandez, Antonio, additional, Honig, Stanton C., additional, Hotta, Yuji, additional, Kannady, Chris, additional, Kimura, Kazunori, additional, Kothandaraman, Narasimhan, additional, Kovac, Jason R., additional, Kumar, Shiv B., additional, La Nasa, Joseph A., additional, Lao, Michael, additional, Liu, James, additional, McAbee, Kara E., additional, Mohan, Chandra, additional, Parikh, Malhar J., additional, Pederzoli, Filippo, additional, Pendergraft, Samuel S., additional, Pressman, Angela, additional, Raheem, Omer A., additional, Rajasekaran, Mahadevan R., additional, Reddy, Amit, additional, Rehman, Ibraheem, additional, Rezk, Bashir M., additional, Roychoudhury, Shubhadeep, additional, Sadri-Ardekani, Hooman, additional, Saldiva, Paulo Hilário N., additional, Sikka, Suresh C., additional, Skouros, Sotirios, additional, Sofikitis, Nikolaos, additional, Takenaka, Atsushi, additional, Tolahunase, Madhuri, additional, Traish, Abdulmaged M., additional, Trost, Landon, additional, Tue Nguyen, Hoang M., additional, Veras, Mariana M., additional, Wang, Run, additional, and Wymer, Kevin, additional

Published
2018
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25. Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology

Author

Björndahl, Lars, primary, Barratt, Christopher L R, additional, Mortimer, David, additional, Agarwal, Ashok, additional, Aitken, Robert J, additional, Alvarez, Juan G, additional, Aneck-Hahn, Natalie, additional, Arver, Stefan, additional, Baldi, Elisabetta, additional, Bassas, Lluís, additional, Boitrelle, Florence, additional, Bornman, Riana, additional, Carrell, Douglas T, additional, Castilla, José A, additional, Cerezo Parra, Gerardo, additional, Check, Jerome H, additional, Cuasnicu, Patricia S, additional, Darney, Sally Perreault, additional, de Jager, Christiaan, additional, De Jonge, Christopher J, additional, Drevet, Joël R, additional, Drobnis, Erma Z, additional, Du Plessis, Stefan S, additional, Eisenberg, Michael L, additional, Esteves, Sandro C, additional, Evgeni, Evangelini A, additional, Ferlin, Alberto, additional, Garrido, Nicolas, additional, Giwercman, Aleksander, additional, Goovaerts, Ilse G F, additional, Haugen, Trine B, additional, Henkel, Ralf, additional, Henningsohn, Lars, additional, Hofmann, Marie-Claude, additional, Hotaling, James M, additional, Jedrzejczak, Piotr, additional, Jouannet, Pierre, additional, Jørgensen, Niels, additional, Kirkman Brown, Jackson C, additional, Krausz, Csilla, additional, Kurpisz, Maciej, additional, Kvist, Ulrik, additional, Lamb, Dolores J, additional, Levine, Hagai, additional, Loveland, Kate L, additional, McLachlan, Robert I, additional, Mahran, Ali, additional, Maree, Liana, additional, Martins da Silva, Sarah, additional, Mbizvo, Michael T, additional, Meinhardt, Andreas, additional, Menkveld, Roelof, additional, Mortimer, Sharon T, additional, Moskovtsev, Sergey, additional, Muller, Charles H, additional, Munuce, Maria José, additional, Muratori, Monica, additional, Niederberger, Craig, additional, O’Flaherty, Cristian, additional, Oliva, Rafael, additional, Ombelet, Willem, additional, Pacey, Allan A, additional, Palladino, Michael A, additional, Ramasamy, Ranjith, additional, Ramos, Liliana, additional, Rives, Nathalie, additional, Roldan, Eduardo Rs, additional, Rothmann, Susan, additional, Sakkas, Denny, additional, Salonia, Andrea, additional, Sánchez-Pozo, Maria Cristina, additional, Sapiro, Rosanna, additional, Schlatt, Stefan, additional, Schlegel, Peter N, additional, Schuppe, Hans-Christian, additional, Shah, Rupin, additional, Skakkebæk, Niels E, additional, Teerds, Katja, additional, Toskin, Igor, additional, Tournaye, Herman, additional, Turek, Paul J, additional, van der Horst, Gerhard, additional, Vazquez-Levin, Monica, additional, Wang, Christina, additional, Wetzels, Alex, additional, Zeginiadou, Theodosia, additional, and Zini, Armand, additional

Published
2022
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39. Standards in semen examination:publishing reproducible and reliable data based on high-quality methodology

Author

Björndahl, Lars, Barratt, Christopher L.R., Mortimer, David, Agarwal, Ashok, Aitken, Robert J., Alvarez, Juan G., Aneck-Hahn, Natalie, Arver, Stefan, Baldi, Elisabetta, Bassas, Lluís, Boitrelle, Florence, Bornman, Riana, Carrell, Douglas T., Castilla, José A., Cerezo Parra, Gerardo, Check, Jerome H., Cuasnicu, Patricia S., Darney, Sally Perreault, de Jager, Christiaan, De Jonge, Christopher J., Drevet, Joël R., Drobnis, Erma Z., Du Plessis, Stefan S., Eisenberg, Michael L., Esteves, Sandro C., Evgeni, Evangelini A., Ferlin, Alberto, Garrido, Nicolas, Giwercman, Aleksander, Goovaerts, Ilse G.F., Haugen, Trine B., Henkel, Ralf, Henningsohn, Lars, Hofmann, Marie Claude, Hotaling, James M., Jedrzejczak, Piotr, Jouannet, Pierre, Jørgensen, Niels, Kirkman Brown, Jackson C., Krausz, Csilla, Kurpisz, Maciej, Kvist, Ulrik, Lamb, Dolores J., Levine, Hagai, Loveland, Kate L., McLachlan, Robert I., Mahran, Ali, Maree, Liana, Martins da Silva, Sarah, Mbizvo, Michael T., Meinhardt, Andreas, Menkveld, Roelof, Mortimer, Sharon T., Moskovtsev, Sergey, Muller, Charles H., Munuce, Maria José, Muratori, Monica, Niederberger, Craig, O'Flaherty, Cristian, Oliva, Rafael, Ombelet, Willem, Pacey, Allan A., Palladino, Michael A., Ramasamy, Ranjith, Ramos, Liliana, Rives, Nathalie, Roldan, Eduardo Rs, Rothmann, Susan, Sakkas, Denny, Salonia, Andrea, Sánchez-Pozo, Maria Cristina, Sapiro, Rosanna, Schlatt, Stefan, Schlegel, Peter N., Schuppe, Hans Christian, Shah, Rupin, Skakkebæk, Niels E., Teerds, Katja, Toskin, Igor, Tournaye, Herman, Turek, Paul J., van der Horst, Gerhard, Vazquez-Levin, Monica, Wang, Christina, Wetzels, Alex, Zeginiadou, Theodosia, Zini, Armand, Björndahl, Lars, Barratt, Christopher L.R., Mortimer, David, Agarwal, Ashok, Aitken, Robert J., Alvarez, Juan G., Aneck-Hahn, Natalie, Arver, Stefan, Baldi, Elisabetta, Bassas, Lluís, Boitrelle, Florence, Bornman, Riana, Carrell, Douglas T., Castilla, José A., Cerezo Parra, Gerardo, Check, Jerome H., Cuasnicu, Patricia S., Darney, Sally Perreault, de Jager, Christiaan, De Jonge, Christopher J., Drevet, Joël R., Drobnis, Erma Z., Du Plessis, Stefan S., Eisenberg, Michael L., Esteves, Sandro C., Evgeni, Evangelini A., Ferlin, Alberto, Garrido, Nicolas, Giwercman, Aleksander, Goovaerts, Ilse G.F., Haugen, Trine B., Henkel, Ralf, Henningsohn, Lars, Hofmann, Marie Claude, Hotaling, James M., Jedrzejczak, Piotr, Jouannet, Pierre, Jørgensen, Niels, Kirkman Brown, Jackson C., Krausz, Csilla, Kurpisz, Maciej, Kvist, Ulrik, Lamb, Dolores J., Levine, Hagai, Loveland, Kate L., McLachlan, Robert I., Mahran, Ali, Maree, Liana, Martins da Silva, Sarah, Mbizvo, Michael T., Meinhardt, Andreas, Menkveld, Roelof, Mortimer, Sharon T., Moskovtsev, Sergey, Muller, Charles H., Munuce, Maria José, Muratori, Monica, Niederberger, Craig, O'Flaherty, Cristian, Oliva, Rafael, Ombelet, Willem, Pacey, Allan A., Palladino, Michael A., Ramasamy, Ranjith, Ramos, Liliana, Rives, Nathalie, Roldan, Eduardo Rs, Rothmann, Susan, Sakkas, Denny, Salonia, Andrea, Sánchez-Pozo, Maria Cristina, Sapiro, Rosanna, Schlatt, Stefan, Schlegel, Peter N., Schuppe, Hans Christian, Shah, Rupin, Skakkebæk, Niels E., Teerds, Katja, Toskin, Igor, Tournaye, Herman, Turek, Paul J., van der Horst, Gerhard, Vazquez-Levin, Monica, Wang, Christina, Wetzels, Alex, Zeginiadou, Theodosia, and Zini, Armand

Abstract

Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.

Published
2022

40. Standards in semen examination : publishing reproducible and reliable data based on high-quality methodology

Author

Björndahl, Lars, Barratt, Christopher L.R., Mortimer, David, Agarwal, Ashok, Aitken, Robert J., Alvarez, Juan G., Aneck-Hahn, Natalie, Arver, Stefan, Baldi, Elisabetta, Bassas, Lluís, Boitrelle, Florence, Bornman, Riana, Carrell, Douglas T., Castilla, José A., Cerezo Parra, Gerardo, Check, Jerome H., Cuasnicu, Patricia S., Darney, Sally Perreault, de Jager, Christiaan, De Jonge, Christopher J., Drevet, Joël R., Drobnis, Erma Z., Du Plessis, Stefan S., Eisenberg, Michael L., Esteves, Sandro C., Evgeni, Evangelini A., Ferlin, Alberto, Garrido, Nicolas, Giwercman, Aleksander, Goovaerts, Ilse G.F., Haugen, Trine B., Henkel, Ralf, Henningsohn, Lars, Hofmann, Marie Claude, Hotaling, James M., Jedrzejczak, Piotr, Jouannet, Pierre, Jørgensen, Niels, Kirkman Brown, Jackson C., Krausz, Csilla, Kurpisz, Maciej, Kvist, Ulrik, Lamb, Dolores J., Levine, Hagai, Loveland, Kate L., McLachlan, Robert I., Mahran, Ali, Maree, Liana, Martins da Silva, Sarah, Mbizvo, Michael T., Meinhardt, Andreas, Menkveld, Roelof, Mortimer, Sharon T., Moskovtsev, Sergey, Muller, Charles H., Munuce, Maria José, Muratori, Monica, Niederberger, Craig, O'Flaherty, Cristian, Oliva, Rafael, Ombelet, Willem, Pacey, Allan A., Palladino, Michael A., Ramasamy, Ranjith, Ramos, Liliana, Rives, Nathalie, Roldan, Eduardo Rs, Rothmann, Susan, Sakkas, Denny, Salonia, Andrea, Sánchez-Pozo, Maria Cristina, Sapiro, Rosanna, Schlatt, Stefan, Schlegel, Peter N., Schuppe, Hans Christian, Shah, Rupin, Skakkebæk, Niels E., Teerds, Katja, Toskin, Igor, Tournaye, Herman, Turek, Paul J., van der Horst, Gerhard, Vazquez-Levin, Monica, Wang, Christina, Wetzels, Alex, Zeginiadou, Theodosia, Zini, Armand, Björndahl, Lars, Barratt, Christopher L.R., Mortimer, David, Agarwal, Ashok, Aitken, Robert J., Alvarez, Juan G., Aneck-Hahn, Natalie, Arver, Stefan, Baldi, Elisabetta, Bassas, Lluís, Boitrelle, Florence, Bornman, Riana, Carrell, Douglas T., Castilla, José A., Cerezo Parra, Gerardo, Check, Jerome H., Cuasnicu, Patricia S., Darney, Sally Perreault, de Jager, Christiaan, De Jonge, Christopher J., Drevet, Joël R., Drobnis, Erma Z., Du Plessis, Stefan S., Eisenberg, Michael L., Esteves, Sandro C., Evgeni, Evangelini A., Ferlin, Alberto, Garrido, Nicolas, Giwercman, Aleksander, Goovaerts, Ilse G.F., Haugen, Trine B., Henkel, Ralf, Henningsohn, Lars, Hofmann, Marie Claude, Hotaling, James M., Jedrzejczak, Piotr, Jouannet, Pierre, Jørgensen, Niels, Kirkman Brown, Jackson C., Krausz, Csilla, Kurpisz, Maciej, Kvist, Ulrik, Lamb, Dolores J., Levine, Hagai, Loveland, Kate L., McLachlan, Robert I., Mahran, Ali, Maree, Liana, Martins da Silva, Sarah, Mbizvo, Michael T., Meinhardt, Andreas, Menkveld, Roelof, Mortimer, Sharon T., Moskovtsev, Sergey, Muller, Charles H., Munuce, Maria José, Muratori, Monica, Niederberger, Craig, O'Flaherty, Cristian, Oliva, Rafael, Ombelet, Willem, Pacey, Allan A., Palladino, Michael A., Ramasamy, Ranjith, Ramos, Liliana, Rives, Nathalie, Roldan, Eduardo Rs, Rothmann, Susan, Sakkas, Denny, Salonia, Andrea, Sánchez-Pozo, Maria Cristina, Sapiro, Rosanna, Schlatt, Stefan, Schlegel, Peter N., Schuppe, Hans Christian, Shah, Rupin, Skakkebæk, Niels E., Teerds, Katja, Toskin, Igor, Tournaye, Herman, Turek, Paul J., van der Horst, Gerhard, Vazquez-Levin, Monica, Wang, Christina, Wetzels, Alex, Zeginiadou, Theodosia, and Zini, Armand

Abstract

Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.

Published
2022

47. Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 US Cohorts

Author

Welch, Barrett M., Keil, Alexander P., Buckley, Jessie P., Calafat, Antonia M., Christenbury, Kate E., Engel, Stephanie M., O'Brien, Katie M., Rosen, Emma M., James-Todd, Tamarra, Zota, Ami R., Ferguson, Kelly K., Alshawabkeh, Akram N., Cordero, José F., Meeker, John D., Barrett, Emily S., Bush, Nicole R., Nguyen, Ruby H. N., Sathyanarayana, Sheela, Swan, Shanna H, Cantonwine, David E., McElrath, Thomas F., Aalborg, Jenny, Dabelea, Dana, Starling, Anne P., Hauser, Russ, Messerlian, Carmen, Zhang, Yu, Bradman, Asa, Eskenazi, Brenda, Harley, Kim G., Holland, Nina, Bloom, Michael S., Newman, Roger B., Wenzel, Abby G., Braun, Joseph M., Lanphear, Bruce P., Yolton, Kimberly, Factor-Litvak, Pam, Herbstman, Julie B., Rauh, Virginia A., Drobnis, Erma Z., Sparks, Amy E., Redmon, J. Bruce, Wang, Christina, Binder, Alexandra M., Michels, Karin B., Baird, Donna D., Jukic, Anne Marie Z., Weinberg, Clarice R., Wilcox, Allen J., Rich, David Q., Weinberger, Barry, Padmanabhan, Vasantha, Watkins, Deborah J., Hertz-Picciotto, Irva, and Schmidt, Rebecca J.

Abstract

IMPORTANCE: Phthalate exposure is widespread among pregnant women and may be a risk factor for preterm birth. OBJECTIVE: To investigate the prospective association between urinary biomarkers of phthalates in pregnancy and preterm birth among individuals living in the US. DESIGN, SETTING, AND PARTICIPANTS: Individual-level data were pooled from 16 preconception and pregnancy studies conducted in the US. Pregnant individuals who delivered between 1983 and 2018 and provided 1 or more urine samples during pregnancy were included. EXPOSURES: Urinary phthalate metabolites were quantified as biomarkers of phthalate exposure. Concentrations of 11 phthalate metabolites were standardized for urine dilution and mean repeated measurements across pregnancy were calculated. MAIN OUTCOMES AND MEASURES: Logistic regression models were used to examine the association between each phthalate metabolite with the odds of preterm birth, defined as less than 37 weeks of gestation at delivery (n = 539). Models pooled data using fixed effects and adjusted for maternal age, race and ethnicity, education, and prepregnancy body mass index. The association between the overall mixture of phthalate metabolites and preterm birth was also examined with logistic regression. G-computation, which requires certain assumptions to be considered causal, was used to estimate the association with hypothetical interventions to reduce the mixture concentrations on preterm birth. RESULTS: The final analytic sample included 6045 participants (mean [SD] age, 29.1 [6.1] years). Overall, 802 individuals (13.3%) were Black, 2323 (38.4%) were Hispanic/Latina, 2576 (42.6%) were White, and 328 (5.4%) had other race and ethnicity (including American Indian/Alaskan Native, Native Hawaiian, >1 racial identity, or reported as other). Most phthalate metabolites were detected in more than 96% of participants. Higher odds of preterm birth, ranging from 12% to 16%, were observed in association with an interquartile range increase in urinary concentrations of mono-n-butyl phthalate (odds ratio [OR], 1.12 [95% CI, 0.98-1.27]), mono-isobutyl phthalate (OR, 1.16 [95% CI, 1.00-1.34]), mono(2-ethyl-5-carboxypentyl) phthalate (OR, 1.16 [95% CI, 1.00-1.34]), and mono(3-carboxypropyl) phthalate (OR, 1.14 [95% CI, 1.01-1.29]). Among approximately 90 preterm births per 1000 live births in this study population, hypothetical interventions to reduce the mixture of phthalate metabolite levels by 10%, 30%, and 50% were estimated to prevent 1.8 (95% CI, 0.5-3.1), 5.9 (95% CI, 1.7-9.9), and 11.1 (95% CI, 3.6-18.3) preterm births, respectively. CONCLUSIONS AND RELEVANCE: Results from this large US study population suggest that phthalate exposure during pregnancy may be a preventable risk factor for preterm delivery.

Published
2022
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48. Sperm Cohort-Specific Zinc Signature Acquisition and Capacitation-Induced Zinc Flux Regulate Sperm-Oviduct and Sperm-Zona Pellucida Interactions

Author

Kerns, Karl, primary, Sharif, Momal, additional, Zigo, Michal, additional, Xu, Wei, additional, Hamilton, Lauren E., additional, Sutovsky, Miriam, additional, Ellersieck, Mark, additional, Drobnis, Erma Z., additional, Bovin, Nicolai, additional, Oko, Richard, additional, Miller, David, additional, and Sutovsky, Peter, additional

Published
2020
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