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391 results on '"Dreher, E"'

3. Effectiveness of local, collaborative, stepped and personalized care management for older people with chronic diseases

Author

Metzner, G, Horstmeier, LM, Bitzer, EM, Dreher, E, Göhner, A, Himmelsbach, I, Kaier, K, Kiekert, J, Kohler, K, Laubner, K, Lyssenko, L, Maun, A, Salm, C, Seufert, J, Voigt-Radloff, S, and Farin-Glattacker, E

Subjects
ddc: 610, Medicine and health
Abstract

Background: During the past decades, life expectancy improved significantly in Western societies. Consequently, the number of elderly people with multiple coexisting chronic diseases, called multimorbidity, increased as well. In Germany, multimorbid elderly frequently face fragmented health care support [for full text, please go to the a.m. URL]

Published
2022
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4. Reduktion pflegerelevanter Risiken älterer Patient*innen während und nach dem Krankenhausaufenthalt – Studienprotokoll einer clusterrandomisierten Studie

Author

von der Warth, R, Göhner, A, Dreher, E, Kentischer, F, Maurer, C, Brühmann, BA, Maun, A, Minin, V, Salm, C, Ritzi, A, Voigt-Radloff, S, and Farin-Glattacker, E

Subjects
ddc: 610, Medicine and health
Abstract

Hintergrund und Stand (inter)nationaler Forschung: Geriatrische Patient*innen sind gekennzeichnet durch eine altersbedingt herabgesetzte Belastbarkeit (Frailty) und häufig multimorbid erkrankt. Im Rahmen einer akuten Hospitalisierung erleben sie ein erhöhtes Risiko für Immobilität, [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022
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7. Schwangerschaft / Sektio

Author

Wyss, P., Biedermann, K., Häberlein, F., Besek, S., Eberhard, J., Litschgi, M., Eberhard, M., Carosso, C., Braschler, C., Koller, A., Pavic, N., Redlich, M., Ohnacker, H., Zimmermann, R., Huch, A., Ioannidis, K., Steiner, R. A., Wight, E., Haller, U., Dietz, Th. U., Hänggi, W., Birkhäuser, M., Gyr, Th., Dreher, E., Steiner, A., Spichtig, S., Huber, S., Schumacher, A., Locher, S., Lüscher, K. P., Hebisch, G., Kirkinen, P., Haldenmann, R., Huch, R., Breymann, Ch., Richter, Ch., Suter, T., Lauper, U., Probst, W., Hess, Th., Benz, J., Saurenmann, E., Rageth, J. C., Riedler, G. F., and Boöni, R.

Published
1992
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8. Onkologie

Author

Brunner, B., Burkard, W., Steiner, R. A., Walt, H., Heim, T., Rülicke, T., Michel, C., Anliker, M. D., Gasser, A., Maibach, R., Hänggi, W., Dreher, E., Delaloye, J. F., Cuttat, J. F., Coucke, P. A., Douglas, P., DeGrandi, P., Küng, F., Hebisch, G., Seelentag, W., Haller, U., Benz, D., Grabherr, D., Enderlin, F., Iklé, F. A., Lorenz, U., Gyr, Th., Genolet, P. M., Bratschi, H. U., Gorgievski, M., Brandenberger, A. W., Rüdlinger, R., Sauthier, Ph., Spuhler, S., Genolet, P.-M., von Dach, B., Fehr, M., Schär, G., Magdeburg, W., Davis, J. B., Lütolf, U. M., Tran, L., Leyvraz, S., Bauer, J., Kovaliv, P., Bossart, H., Laurini, R. N., and Tapià, J. E.

Published
1992
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9. Endoskopie/ Gynäkologie

Author

Spörri, St., Frenz, M., Altermatt, H. J., Bratschi, H. U., Romano, V., Forrer, M., Weber, H. P., Hagmann, P. D., Jung, J., Lang, P. F., Spira, J.-C., Spira, J. C., Lang, P., Gyr, Th., Dreher, E., Mathez-Loic, F., Steiner, R. A., Jemec, M., Haller, U., Fehr, M., Fink, D., Ioannidis, K., Wight, E., Schär, G., Sievi, J., Müller, R., Menell, P., Braschler, C., Carosso, C., Eberhard, M., and Litschgi, M.

Published
1992
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15. Le traitement medical par tamoxifene comme traitement primaire dans les cancers du sein non operes chez des patientes agees

Author

Matute, J. C., Spinosa, J. P., Schäfer, P., Krauer, F., Genolet, P. -M., Delaloye, J. -F., De Grandi, P., Hornung, R., Jentsch, B., Crompton, N. E. A., Haller, U., Walt, H., Gayer, R., Dürig, P., Dreher, E., Altermatt, H. J., Hess, Th., Peschers, U., Schüssler, B., Riedler, G., Rinderknecht, B., Meister, F., Bänziger, K. -H., Giudici, G., and Stoll, W.

Published
1995
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16. Freie mitteilungen

Author

Wyss-Desserich, M. -Th., Caduff-Joos, R., Wyss, P., Rageth, Ch., Wight, E., walt, H., Haller, U., Schäfer, P., Schneider, J., Spinosa, J. P., Krauer, F., Köchli, O. R., Schär, G., Schenk, V., Fink, D., Hornung, R., Eppenberger, U., Müller, H., Haller, U., Kunz, J., Rondez, R., Pagotto, R. F., Siegrist, W., Benz, P., Benz-Baumann, B., Benz, J., Rutsch, M., Benz-Baumann, B., Benz, J., Bitzer, J., Saurer, K., Hänggi, W., Isenschmid, M., Lachat, R., Dreher, E., Schneider, J., Schäfer, P., Spinosa, J. P., and Krauer, F.

Published
1995
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26. Umbilical endometriosis

Author

Frischknecht, F., Raio, L., Fleischmann, A., Dreher, E., Lüscher, K. P., Mueller, M. D., Frischknecht, F., Raio, L., Fleischmann, A., Dreher, E., Lüscher, K. P., and Mueller, M. D.

Abstract

We report two women who presented with a recurrent, mildly painful, bluish nodule in the umbilicus. Both patients complained of local tenderness and occasional bleeding that increased during menstruation. Neither patient had had previous pelvic surgery. Excision of the lesions revealed a primary umbilical endometriosis; in one case, a simultaneous laparoscopy showed a pelvic endometriosis. We review the current literature and discuss the possible etiopathogenesis and when a laparoscopy is indicated to diagnose a concomitant pelvic endometriosis. Umbilical endometriosis is a very rare disease but should be considered in the differential diagnosis of umbilical lesions

Published
2018

31. SHALL PUPILS DRILL? MILITARY IN THE SCHOOLS

Author

Pearse, C. G., Prince, J. T., Steward, Darius, Towle, C. B., Bardeen, C. W., Finch, Adelaide V., McKay, J. G., Roe, Alfred S., Babcock, C. A., Upham, A. A., Jenks, Paul R., Kennedy, John, Dreher, E. S., Tammany, Roman, Powell, Arthur, Sabin, Henry, Lane, F. R., Atkinson, Fred W., Twitmyer, Edwin, Wright, R. N., Millspaugh, J. F., and Foster, James H.

Published
1898

33. Urodynamik

Author

Leisner, B., Koch, J., Mayr, B., Moser, E. A., Faber, P., Deck, H. J., Herberger, J., Schmidt, H., Heidenreich, J., Grüneberger, A., Geier, G., Eberhard, J., Krajnović, P., Oberhofer, S., Zubec, Z., Würth, K., Dreher, E., Eduah, S. B., Adam, P., v. Fischer, B., Heidenreich, J., Faber, P., Deck, H. J., Herberger, J., Deck, H. J., Schmidt-Rimpler, J., Faber, P., Heidenreich, J., Articus, M., Staufer, F., Lochmüller, H., Lienhard, P., Furrer, M., Eberhard, J., Kümper, H. J., Richter, K., Pickart, M., Koch, J., Heinz, F., Heidenreich, J., Faber, P., Deck, H. J., Jonas, U., Petri, E., Adam, P. J., v. Fischer, B., Dreher, E., Koutifaris, B., Nestoridis, N., Christodoulakos, G., Kalogirou, D., Altmann, P., Petri, E., Jonas, U., Tammen, H., Krieglsteiner, P., Achhammer, I., Graatz, B., Parache, J., Gonzales Chavez, G., Zerolo, J. M., Fdez Robayana, F., Ojeda, A., and Cotter, A.

Published
1979
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34. Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast

Author

Berclaz, G., Altermatt, H. J., Rohrbach, V., Kieffer, I., Dreher, E., Andres, A.-C, Berclaz, G., Altermatt, H. J., Rohrbach, V., Kieffer, I., Dreher, E., and Andres, A.-C

Abstract

Summary Background: Axl, a member of a family of receptor tyrosine kinases characterized by an extracellular domain resembling cell adhesion molecules and an intracellular conserved tyrosine kinase domain has been reported to induce cell proliferation and transformation. In mice, axl is expressed in the normal mammary gland and over-expressed in aggressive mammary tumors. Patients and methods: We have investigated the expression of axl immunohistochemically in 23 normal human breast samples and in 111 consecutive breast carcinomas. Expression of axl was correlated with tumour characteristics (lymph node involvement, stage, grade) and immunohistochemical expression of ER, PR, Ki-67 and c-erbB-2. Results: In normal tissue, axl localizes to the membrane of breast epithelial cells. Axl protein shows membrane associated staining in high correlation (P = 0.004) with the expression of the estrogen receptor (ER). Axl expression was found in a subset of breast carcinomas and was also correlated with high significance (P < 0.0001) with the presence of ER. Conclusion: Our results suggest that axl may serve as a mediator of estrogen stimulation preventing the completion of the breast epithelial life cycle and that estrogen induced axl expression may give a survival signal to cancerous cells, preventing them from dying through apoptosis

Published
2017

35. Activation of the receptor protein tyrosine kinase EphB4 in endometrial hyperplasia and endometrial carcinoma

Author

Berclaz, G., Karamitopoulou, E., Mazzucchelli, L., Rohrbach, V., Dreher, E., Ziemiecki, A., Andres, A.-C, Berclaz, G., Karamitopoulou, E., Mazzucchelli, L., Rohrbach, V., Dreher, E., Ziemiecki, A., and Andres, A.-C

Abstract

Background: Members of the Eph family of tyrosine kinases have been implicated in embryonic pattern formation and vascular development; however, little is known about their role in the adult organism. We have observed estrogen-dependent EphB4 expression in the normal breast suggesting its implication in the hormone-controlled homeostasis of this organ. Since the endometrium is a similarly hormone dependent organ and endometrial carcinoma is thought to result from estrogenic stimulation, we have investigated EphB4 expression in normal human endometrium and during its carcinogenesis. Patients and methods: EphB4 expression was analyzed immunohistochemically in 26 normal endometrium specimens, 15 hyperplasias and 102 endometrioid adenocarcinomas and correlated with clinical and prognostic tumor characteristics. Results: In normal endometrial tissue no EphB4 protein was detected. Strikingly, we observed a drastic increase (P <0.0001) in the number of EphB4 protein-expressing glandular epithelial cells in the majority of hyperplasias and carcinomas. Moreover, we found a statistically highly significant positive correlation between EphB4 expression and post-menopausal stage of the patient (P = 0.007). Conclusions: These findings indicate that in the endometrium, EphB4 is an early indicator of malignant development and, thus, EphB4 may represent a potent tool for diagnosis and therapeutic intervention

Published
2017

36. Notfälle in der Gynäkologie – was darf ich nicht vergessen?

Author

Kuhn A and Dreher E

Subjects
General Medicine
Abstract

Notfälle in der Gynäkologie sind häufig und können wegen abdominaler Schmerzen, Juckreiz, utero-vaginaler Blutung, Vergewaltigung, Notfallkontrazeption, Fremdkörper, Senkungen und Harnwegsinfektionen zur Konsultation führen. Es ist wichtig, bei Patientinnen im fertilen Alter an eine Schwangerschaft zu denken. Vaginale Blutungen können durch Atrophie, durch Infektion, Karzinom oder schwangerschaftsbedingt sein; in letzterem Fall ist es wichtig, zwischen Extrauteringravidität, pathologischer oder physiologischer intrauteriner Gravidität zu unterscheiden. Bei postmenopausalen Blutungen sind weitere gynäkologische Abklärungen durch den Facharzt obligatorisch, um ein Karzinom auszuschließen. Nach Vergewaltigung benötigen die Patientinnen psychologische, forensische und gynäkologische Beratung. Sexuell übertragbare Krankheiten, HIV inklusive, müssen ausgeschlossen werden und gegebenenfalls prophylaktische Medikamente gegeben werden. Falls ungeschützter Geschlechtsverkehr stattgefunden hat, kann die «Pille danach» für 72 Stunden eingesetzt werden oder eine Spirale bis fünf Tage postkoital. Senkungen sind selten ein akutes Problem. Sie können allerdings zur Harnretention führen. Harnwegsinfekte sind ein häufiges Problem und sollten antibiotisch therapiert werden.

Published
2005
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40. Kurzvorträge und Poster zum Thema (Ausgenommen Urologie)

Author

Bender, H. G., Beck, L., Kurz, K. H., Koenig, U. D., Lang, Norbert, Meyenburg, M., Pachaly, J., Daume, E., Simoneit, G., Hölzl, M., Bredow, M., Hohlweg-Majert, P., Seiler, W., Gitsch, E., Janisch, H., Tulzer, H., Baltzer, J., Köpcke, W., Lohe, K. J., Kaufmann, C., Ober, K. G., Zander, I., Holzer, E., Berger, M., Dreher, E., Fatzer, S., Locher, G. W., Majewski, A., Börner, P., Böhme, U., Zimmermann, P., Bender, H. G., Staib, R., Strasser, K., Drähne, A., Amann, G., Biedermann, H. D., Diekmann, Kunz, S., Decker, K., Herbst, S., Hirsch, H. A., Semm, K., Weil, A., Baumann, U., Schenk, W., Babenerd, J., Flehr, I., Neeser, E., Hirsch, H. A., Neubüser, D., Mußmann, D. J., Heckeroth, V., Koenig, U. D., Giesel, H., Mettler, L., Semm, K., Scheidel, P., Hepp, H., Intraphuvasak, J., Scheidel, P., Hepp, H., Anderer, M., Neeser, E., Hirsch, H. A., Decker, K., Neeser, E., Riedel, H. -H., Semm, K., Menken, F. C., Zielske, F., Jaluvka, V., Lübke, F., Frangenheim, H., Fleiner, R., Decker, K., Semm, K., Neeser, E., Anderer, M., Hirsch, H. A., Frantzen, Ch., Schlößer, H. W., Beck, L., Lübke, F., Moayer, M., Jacobs, K. F., Kaufmann, M., Komitowski, D., Schneider-Affeld, F., Kubli, F., Beckmann, M., Hassenbürger, J., Wagner, H., Beller, F. K., Hüter, J., Clemens, H., Ogbukagu, A., Knapstein, P., Bauer, H., Herzog, R., Meyer-Menk, W. Th., Hüter, J., Chatter, M., Klingemann, H., Hüter, J., Schinzel, Th., Knapstein, P., Bauer, H., Hüter, J., Clemens, H., Ogbukagu, A., Hüter-Löliger, S., Meyer-Menk, W. Th., Schinzel, Th., Meyer-Menk, W. Th., Hüter, J., Chatter, M., Hassenbürger, J., Beckmann, M., Wagner, H., Beller, F. K., Schneider-Affeld, F., Kubli, F., Krämer, G., Kaufmann, M., and Perez Gay, Barbara M.

Published
1979
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43. Moderatorenbericht Podiumsgespräch: Ambulantes Operieren

Author

Schmidt-Matthiesen, H., Beck, L., Blauert, K. H., Brückner, W., Doench, K., Landauer, B., Kunz, S., Hirsch, H. A., Roemer, V. M., Lahodny, J., Hillemanns, H. G., Kaltenbach, F. J., Siebers, J. W., Krüger, H. J., de Gregorio, D., Berg, D., Frühwirth, O., Kriesche, H., Noll, C., Müller-Holve, W., Schneider-Affeld, F., Fabinger, R., Garbe, U., Shakra, K., Martin, K., Langenkamp, O., Steyer, M., Heidenreich, J., Peters, F. D., Roemer, V. M., Parys, S., Gieren, S., von Fischer, B., Flückiger, A., Dreher, E., Wende, I., Grüneberger, A., Briel, R. C., Hirsch, H. A., Verhoeven, H. C., Schlösser, H. W., Frantzen, C., Albrich, W., Götz, A., Kleinstein, J., Neubüser, D., Habermann, B., Wiedemann, R., Mootz, U., Beier, H. M., Hepp, H., Zwiens, G., Nitschke-Dabelstein, S., Böger, A., Lüttges, J., Inthraphuvasak, J., Stofft, E., Osada, H., Friedberg, V., Diedrich, K., Lehmann, F., Al-Hasani, S., van der Ven, H., Krebs, D., Feichtinger, W., Szalay, S., Kemeter, P., van der Ven, H. H., Jeyendran, R. S., Zaneveld, L. J. D., Drebs, D., Garbe, U., Fabinger, R., Naether, O., Martin, K., Schnell, C., Molkenthin, A., Siebert, W., Arnold, H. -G., Klöck, F. -K., Harms, E., Christmann, U., Kopecky, P., Mager, J., Postulka, U., Wenner, W., Angelkort, B., Gerstner, G., Kofler, E., and Rotter, M.

Published
1983
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45. Kurzvorträge und Poster zum Thema Schwangerschaftsabbruch

Author

Höbich, D., Brünig, R., Schmidt-Gollwitzer, K., Hoyme, U., Decker, K., Wilken, H., Eckardt, W., Peters, F. D., Hirsch, H. A., v. Trotha, A., Behrendt, M., Walz, K. A., Fischer, W. M., Ludwig, H., Höbich, D., Gaerret-Bleek, N., Granitzka, S., Siedentopf, H. -G., Nuripur, M., Mangold, S., Anderer, M., Schweppe, K. -W., Immand, H., Lueken, R. P., Gallinat, A., Lindemann, H. J., Kunz, J., Gerig, B., Sievers, S., Wiest, W., Dallenbach-Hellweg, G., Schleich, A., Mignon, P., Lippert, T. H., Peters, F. D., Kunz, S., Anderer, M., Rauskolb, R., Schiller, V., Maack, N., Bayer, H., Halle, H., Walz, K. A., Behrendt, M., Trotha, A. v., Fischer, W. M., Ludwig, H., Beck, A., Sterijev, K., Feichter, G. E., Tauber, P. F., Rosenthal, E., Nohlen, M., Ludwig, H., Sarembe, B., Lichtenegger, W., Lirmberger, M., Runte, K. P., Maas, D. H. A., Cornely, M., Weitzel, H., Hoppen, H. -O., Gethmann, U., Gethmann, U., Oberheuser, F., Schmidt-Gollwitzer, K., Schüssler, B., Schmidt-Gollwitzer, M., Schmidt-Gollwitzer, M., Schüssler, B., Schmidt-Gollwitzer, K., Steiner, H., Zahradnik, H. P., Robrecht, D., Hillemanns, H. -G., Lichtenegger, W., Zahradnik, H. P., Beyer, J., Schillfart, R., Steiner, H., Duenhoelter, J. H., Göretzlehner, G., Wilken, H., Rudolf, K., Frahm, R., Wiechell, H., Vujić, J., Ciglar, S., Djurić, N., Profeta, K., Mickan, H., Landherr, F., Zander, J., Hölzel, D., Berle, P., Cornely, M., Kühnle, H., Rath, W., Theobald, P., Ulbrich, R., Grande, P., Grande, P., Kühnle, H., Rath, W., Knabe, H., Lehmann, F., Rath, W., Theobald, P., Ulbrich, R., Grande, P., Kühnle, H., Theobald, P., Ulbrich, R., Grande, P., Kühnle, H., Rath, W., Trolp, R., Beyer, J., Schillfahrt, R., Steiner, H., Zahradnik, H. P., von Ritter, St., Rauskolb, R., Spätling, L., Stähler, E., Ulbrich, R., Grande, P., Kühnle, H., Rath, W., Theobald, P., Heinzl, S., Schneider, M., Andor, J., Kunz, J., Bänninger, U., Keller, P. J., Möller, C. -P., Lehmann, F., Briel, R. C., Lippert, Th., Kidess, E., Roemer, V. M., Dennemark, N., Dreher, E., Müller, M., Zahradnik, H. P., Stengele, E., Scherb, L., and Breckwoldt, M.

Published
1979
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47. ICON2: randomised trial of single-agent carboplatin against three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) in women with ovarian cancer

Author

Parmar MKB, Torri V, Bonaventura A, Bonazzi C, Colombo N, Delaloye JF, Marsoni S, Mangioni C, Sandercock J, Sessa C, Williams C, Tinazzi A, Flann M, Geiser K, Scorpiglione N, Stewart JF, Chaves J, Palmeiro E, Curtain A, McCormack T, Gennatas C, Marras F, Oppo TG, Balestrino M, Malzoni C, Malzoni M, Belli M, Geminiani ML, Crestani G, Monaco A, Vavala V, Piatto E, Barattini G, Fornara PG, Chetri MC, Santeufemia G, Artioli F, Carone D, Fanizza G, Trentadue R, Priolo D, Scollo P, Nigro SC, Petrina M, Mastrantonio P, Spanna GD, Zagni R, Belloni C, Colleoni R, Redaelli L, Cavagnini A, Di Costanzo G, Perroni D, Arienti S, Orfanotti G, Cantoni FM, Secli R, Bianchi A, Martinello R, Mollica G, Maizzi D, Picchiarelli ME, Fiorini G, Borsani M, Colombo E, Garsia S, Melgrati L, Paggi G, Brunenghi GM, Casini M, Isa L, Algeri R, Prozio G, Belfiore G, Angelini F, D'Aprile M, Moreschi M, Mauri ML, Natale N, Senzani FM, Pavanato G, Poggi G, Garuti G, Luerti M, Cruciani G, Pagano F, Baccolo M, Poddi ER, Bocciolone L, Sabelli MA, Maggi R, Restelli C, D'Antona A, Locatelli MC, Pessi A, Raina A, Chiari S, Gabriele A, Pittelli MR, Iacobelli P, Dogliotti L, Gorzegno G, Musso P, Vegna G, Coco G, Alletti DG, Picciotto F, Lucchese V, Epis A, di Palumbo VS, Drudi G, Ravaioli A, Zampella D, Morandi MG, Gorga G, Zucchelli C, Cariello S, Galletto L, Sussio M, Massacesi L, Massacesi M, Carli A, Tucci E, Tajani E, Corrado G, Bumma S, Durando A, Massobrio M, Sberveglieri M, Biasio M, Guercio E, Jura R, Danese S, Wierdis T, Farnelli C, Tarantino G, Grassi R, Repetti F, Rocchi B, Grampa M, Ercoli A, Griso C, Signori E, Zanini L, Presti M, Klimek M, Urbanski K, Biswas A, Viegas O, Kochli O, Dreher E, Fey M, Beck G, Ludin J, Bonnefoi H, Krauer F, Bauer J, Delmore G, Furrer C, Lorenz U, Thurlimann B, Bronz L, Sanna P, Wyss D, Goldhirsch A, Gyr T, Leidi L, Pastorelli G, Pagani O, Rey P, Hailer U, Benz J, Kaye SB, Reed NS, Symonds RP, Atkinson RJ, Axford AT, Rustin G, Seckl MJ, Green JA, Scott IV, Guthrie D, Harper PG, Calman F, Dobbs HJ, Weir P, Cassoni A, Lederman JA, Souhami RL, Bozzino J, Adab F, Redman CWE, Scoble JE, Paterson M, Daniel F, Cowley N, Williams CJ, Spooner D, Hong A, McIllmurray M, Hendy-Ibbs P, Hall V, Iveson TJ, Whitehouse JMA, Garry R, Lamont A, Robinson A, Trask CW, Clubb AW, Murrell D, Newman G, Wilkins M, Goldthorp WO, Roberts JK, Radstone DJ, Whipp MJ, Ledermann JA, Pater J, Buyse M, Omura G, Parmar, Mkb, Torri, V, Bonaventura, A, Bonazzi, C, Colombo, N, Delaloye, Jf, Marsoni, S, Mangioni, C, Sandercock, J, Sessa, C, Williams, C, Tinazzi, A, Flann, M, Geiser, K, Scorpiglione, N, Stewart, Jf, Chaves, J, Palmeiro, E, Curtain, A, Mccormack, T, Gennatas, C, Marras, F, Oppo, Tg, Balestrino, M, Malzoni, C, Malzoni, M, Belli, M, Geminiani, Ml, Crestani, G, Monaco, A, Vavala, V, Piatto, E, Barattini, G, Fornara, Pg, Chetri, Mc, Santeufemia, G, Artioli, F, Carone, D, Fanizza, G, Trentadue, R, Priolo, D, Scollo, P, Nigro, Sc, Petrina, M, Mastrantonio, P, Spanna, Gd, Zagni, R, Belloni, C, Colleoni, R, Redaelli, L, Cavagnini, A, Di Costanzo, G, Perroni, D, Arienti, S, Orfanotti, G, Cantoni, Fm, Secli, R, Bianchi, A, Martinello, R, Mollica, G, Maizzi, D, Picchiarelli, Me, Fiorini, G, Borsani, M, Colombo, E, Garsia, S, Melgrati, L, Paggi, G, Brunenghi, Gm, Casini, M, Isa, L, Algeri, R, Prozio, G, Belfiore, G, Angelini, F, D'Aprile, M, Moreschi, M, Mauri, Ml, Natale, N, Senzani, Fm, Pavanato, G, Poggi, G, Garuti, G, Luerti, M, Cruciani, G, Pagano, F, Baccolo, M, Poddi, Er, Bocciolone, L, Sabelli, Ma, Maggi, R, Restelli, C, D'Antona, A, Locatelli, Mc, Pessi, A, Raina, A, Chiari, S, Gabriele, A, Pittelli, Mr, Iacobelli, P, Dogliotti, L, Gorzegno, G, Musso, P, Vegna, G, Coco, G, Alletti, Dg, Picciotto, F, Lucchese, V, Epis, A, di Palumbo, V, Drudi, G, Ravaioli, A, Zampella, D, Morandi, Mg, Gorga, G, Zucchelli, C, Cariello, S, Galletto, L, Sussio, M, Massacesi, L, Massacesi, M, Carli, A, Tucci, E, Tajani, E, Corrado, G, Bumma, S, Durando, A, Massobrio, M, Sberveglieri, M, Biasio, M, Guercio, E, Jura, R, Danese, S, Wierdis, T, Farnelli, C, Tarantino, G, Grassi, R, Repetti, F, Rocchi, B, Grampa, M, Ercoli, A, Griso, C, Signori, E, Zanini, L, Presti, M, Klimek, M, Urbanski, K, Biswas, A, Viegas, O, Kochli, O, Dreher, E, Fey, M, Beck, G, Ludin, J, Bonnefoi, H, Krauer, F, Bauer, J, Delmore, G, Furrer, C, Lorenz, U, Thurlimann, B, Bronz, L, Sanna, P, Wyss, D, Goldhirsch, A, Gyr, T, Leidi, L, Pastorelli, G, Pagani, O, Rey, P, Hailer, U, Benz, J, Kaye, Sb, Reed, N, Symonds, Rp, Atkinson, Rj, Axford, At, Rustin, G, Seckl, Mj, Green, Ja, Scott, Iv, Guthrie, D, Harper, Pg, Calman, F, Dobbs, Hj, Weir, P, Cassoni, A, Lederman, Ja, Souhami, Rl, Bozzino, J, Adab, F, Redman, Cwe, Scoble, Je, Paterson, M, Daniel, F, Cowley, N, Williams, Cj, Spooner, D, Hong, A, Mcillmurray, M, Hendy-Ibbs, P, Hall, V, Iveson, Tj, Whitehouse, Jma, Garry, R, Lamont, A, Robinson, A, Trask, Cw, Clubb, Aw, Murrell, D, Newman, G, Wilkins, M, Goldthorp, Wo, Roberts, Jk, Radstone, Dj, Whipp, Mj, Ledermann, Ja, Pater, J, Buyse, M, and Omura, G

Published
1998

48. ICON2: randomised trial of single-agent carboplatin against three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) in women with ovarian cancer. ICON Collaborators. International Collaborative Ovarian Neoplasm Study

Author

Parmar, MKB, Torri, V, Bonaventura, A, Bonazzi, C, Delaloye, J, Marsoni, S, Mangioni, C, Sandercock, J, Sessa, C, Williams, C, Tinazzi, A, Flann, M, Geiser, K, Scorpiglione, N, Stewart, J, Chaves, J, Palmeiro, E, Curtain, A, McCormack, T, Gennatas, C, Marras, F, Oppo, T, Balestrino, M, Malzoni, C, Malzoni, M, Belli, M, Geminiani, M, Crestani, G, Monaco, A, Vavala, V, Piatto, E, Barattini, G, Fornara, P, Chetri, M, Santeufemia, G, Artioli, F, Carone, D, Fanizza, G, Trentadue, R, Priolo, D, Scollo, P, Nigro, S, Petrina, M, Mastrantonio, P, Spanna, G, Zagni, R, Belloni, C, Colleoni, R, Redaelli, L, Cavagnini, A, Di Costanzo, G, Perroni, D, Arienti, S, Orfanotti, G, Cantoni, F, Secli, R, Bianchi, A, Martinello, R, Mollica, G, Maizzi, D, Picchiarelli, M, Fiorini, G, Borsani, M, Colombo, E, Garsia, S, Melgrati, L, Paggi, G, Brunenghi, G, Casini, M, Isa, L, Algeri, R, Prozio, G, Belfiore, G, Angelini, F, D'Aprile, M, Moreschi, M, Mauri, M, Natale, N, Senzani, F, Pavanato, G, Poggi, G, Garuti, G, Luerti, M, Cruciani, G, Pagano, F, Baccolo, M, Poddi, E, Bocciolone, L, Sabelli, M, Maggi, R, Restelli, C, D'Antona, A, Locatelli, M, Pessi, A, Raina, A, Chiari, S, Gabriele, A, Pittelli, M, Iacobelli, P, Dogliotti, L, Gorzegno, G, Musso, P, Vegna, G, Coco, G, Alletti, D, Picciotto, F, Lucchese, V, Epis, A, di Palumbo, V, Drudi, G, Ravaioli, A, Zampella, D, Morandi, M, Gorga, G, Zucchelli, C, Cariello, S, Galletto, L, Sussio, M, Massacesi, L, Massacesi, M, Carli, A, Tucci, E, Tajani, E, Corrado, G, Bumma, S, Durando, A, Massobrio, M, Sberveglieri, M, Biasio, M, Guercio, E, Jura, R, Danese, S, Wierdis, T, Farnelli, C, Tarantino, G, Grassi, R, Repetti, F, Rocchi, B, Grampa, M, Ercoli, A, Griso, C, Signori, E, Zanini, L, Presti, M, Klimek, M, Urbanski, K, Biswas, A, Viegas, O, Kochli, O, Dreher, E, Fey, M, Beck, G, Ludin, J, Bonnefoi, H, Krauer, F, Bauer, J, Delmore, G, Furrer, C, Lorenz, U, Thurlimann, B, Bronz, L, Sanna, P, Wyss, D, Goldhirsch, A, Gyr, T, Leidi, L, Pastorelli, G, Pagani, O, Rey, P, Hailer, U, Benz, J, Kaye, S, Reed, N, Symonds, R, Atkinson, R, Axford, A, Rustin, G, Seckl, M, Green, J, Scott, I, Guthrie, D, Harper, P, Calman, F, Dobbs, H, Weir, P, Cassoni, A, Lederman, J, Souhami, R, Bozzino, J, Adab, F, Redman, C, Scoble, J, Paterson, M, Daniel, F, Cowley, N, Spooner, D, Hong, A, McIllmurray, M, Hendy Ibbs, P, Hall, V, Iveson, T, Whitehouse, J, Garry, R, Lamont, A, Robinson, A, Trask, C, Clubb, A, Murrell, D, Newman, G, Wilkins, M, Goldthorp, W, Roberts, J, Radstone, D, Whipp, M, Ledermann, J, Pater, J, Buyse, M, Omura, G., COLOMBO, NICOLETTA, Parmar, M, Torri, V, Bonaventura, A, Bonazzi, C, Colombo, N, Delaloye, J, Marsoni, S, Mangioni, C, Sandercock, J, Sessa, C, Williams, C, Tinazzi, A, Flann, M, Geiser, K, Scorpiglione, N, Stewart, J, Chaves, J, Palmeiro, E, Curtain, A, Mccormack, T, Gennatas, C, Marras, F, Oppo, T, Balestrino, M, Malzoni, C, Malzoni, M, Belli, M, Geminiani, M, Crestani, G, Monaco, A, Vavala, V, Piatto, E, Barattini, G, Fornara, P, Chetri, M, Santeufemia, G, Artioli, F, Carone, D, Fanizza, G, Trentadue, R, Priolo, D, Scollo, P, Nigro, S, Petrina, M, Mastrantonio, P, Spanna, G, Zagni, R, Belloni, C, Colleoni, R, Redaelli, L, Cavagnini, A, Di Costanzo, G, Perroni, D, Arienti, S, Orfanotti, G, Cantoni, F, Secli, R, Bianchi, A, Martinello, R, Mollica, G, Maizzi, D, Picchiarelli, M, Fiorini, G, Borsani, M, Colombo, E, Garsia, S, Melgrati, L, Paggi, G, Brunenghi, G, Casini, M, Isa, L, Algeri, R, Prozio, G, Belfiore, G, Angelini, F, D'Aprile, M, Moreschi, M, Mauri, M, Natale, N, Senzani, F, Pavanato, G, Poggi, G, Garuti, G, Luerti, M, Cruciani, G, Pagano, F, Baccolo, M, Poddi, E, Bocciolone, L, Sabelli, M, Maggi, R, Restelli, C, D'Antona, A, Locatelli, M, Pessi, A, Raina, A, Chiari, S, Gabriele, A, Pittelli, M, Iacobelli, P, Dogliotti, L, Gorzegno, G, Musso, P, Vegna, G, Coco, G, Alletti, D, Picciotto, F, Lucchese, V, Epis, A, di Palumbo, V, Drudi, G, Ravaioli, A, Zampella, D, Morandi, M, Gorga, G, Zucchelli, C, Cariello, S, Galletto, L, Sussio, M, Massacesi, L, Massacesi, M, Carli, A, Tucci, E, Tajani, E, Corrado, G, Bumma, S, Durando, A, Massobrio, M, Sberveglieri, M, Biasio, M, Guercio, E, Jura, R, Danese, S, Wierdis, T, Farnelli, C, Tarantino, G, Grassi, R, Repetti, F, Rocchi, B, Grampa, M, Ercoli, A, Griso, C, Signori, E, Zanini, L, Presti, M, Klimek, M, Urbanski, K, Biswas, A, Viegas, O, Kochli, O, Dreher, E, Fey, M, Beck, G, Ludin, J, Bonnefoi, H, Krauer, F, Bauer, J, Delmore, G, Furrer, C, Lorenz, U, Thurlimann, B, Bronz, L, Sanna, P, Wyss, D, Goldhirsch, A, Gyr, T, Leidi, L, Pastorelli, G, Pagani, O, Rey, P, Hailer, U, Benz, J, Kaye, S, Reed, N, Symonds, R, Atkinson, R, Axford, A, Rustin, G, Seckl, M, Green, J, Scott, I, Guthrie, D, Harper, P, Calman, F, Dobbs, H, Weir, P, Cassoni, A, Lederman, J, Souhami, R, Bozzino, J, Adab, F, Redman, C, Scoble, J, Paterson, M, Daniel, F, Cowley, N, Spooner, D, Hong, A, Mcillmurray, M, Hendy Ibbs, P, Hall, V, Iveson, T, Whitehouse, J, Garry, R, Lamont, A, Robinson, A, Trask, C, Clubb, A, Murrell, D, Newman, G, Wilkins, M, Goldthorp, W, Roberts, J, Radstone, D, Whipp, M, Ledermann, J, Pater, J, Buyse, M, and Omura, G

Subjects
Antineoplastic Combined Chemotherapy Protocol, Ovarian Neoplasm, Alopecia, Leukopenia, Middle Aged, Thrombocytopenia, Carboplatin, Antineoplastic Agent, Doxorubicin, Proportional Hazards Model, Female, Survival Analysi, Cisplatin, Cyclophosphamide, Aged, Human
Abstract

A series of meta-analyses of randomised controlled trials raised the question of whether the three-drug combination of CAP (cyclophosphamide, doxorubicin, and cisplatin) was more or less effective than optimal-dose single-agent carboplatin for women with advanced ovarian cancer.

Published
1998

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