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449 results on '"Dramé, M."'

5. AB0237 DYSPHONIA AND ANTI-Mi2 ANTIBODIES ARE INDEPENDENTLY ASSOCIATED TO DYSPHAGIA IN INDIVIDUALS OF AFRICAN ANCESTRY WITH IDIOPATHIC INFLAMMATORY MYOPATHIES

Author

Suzon, B., primary, Robert, R., additional, Abel, A., additional, Louis-Sidney, F., additional, Felix, A., additional, Amazan, E., additional, Bellance, R., additional, Parsemain, A., additional, Moinet, F., additional, Coco-Viloin, I., additional, Cougnaud, R., additional, Erere Ngayap, C., additional, Dramé, M., additional, and Deligny, C., additional

Published
2024
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6. La dysphonie et les anticorps anti-MI2 sont indépendamment associés à la dysphagie au cours des myopathies inflammatoires en Martinique

Author

Robert, R., primary, Abel, A., additional, Louis-Sidney, F., additional, Felix, A., additional, Cougnaud, R., additional, Parsemain, A., additional, Moinet, F., additional, Coco-Viloin, I., additional, Dramé, M., additional, Amazan, E., additional, Bellance, R., additional, Deligny, C., additional, and Suzon, B., additional

Published
2024
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9. Endométriose thoracique en Martinique

Author

Agossou, M., primary, Gilbert-Sanchez, B., additional, Alauzen, P.H., additional, Maud, O., additional, Cecilia-Joseph, E., additional, Chevalier, L., additional, Jean-Laurent, M., additional, Dramé, M., additional, and Venissac, N., additional

Published
2024
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10. Is Chikungunya Virus Infection an Independent Risk Factor for 2-Year Mortality in Older Afro-Caribbean Subjects?

Author

Godaert L, Nicolon C, Najioullah F, Kanagaratnam L, Césaire R, and Dramé M

Subjects
chikungunya, survival, elderly people, hospital admission, Infectious and parasitic diseases, RC109-216
Abstract

Lidvine Godaert,1 Camille Nicolon,2 Fatiha Najioullah,3 Lukshe Kanagaratnam,4 Raymond Césaire,3,5 Moustapha Dramé5,6 1Department of Geriatrics, General Hospital of Valenciennes, Valenciennes, France; 2Department of Geriatrics, Hospital of Marennes, Marennes, France; 3Department of Virology, University Hospitals of Martinique, Fort-de-France, Martinique; 4Department of Research and Public Health, University Hospitals of Reims, Reims, France; 5Faculty of Medicine, University of French West Indies, Fort-de-France, Martinique; 6Department of Research and Innovation, University Hospitals of Martinique, Fort-de-France, MartiniqueCorrespondence: Moustapha DraméDepartment of Research and Innovation - CS 90632, University Hospitals of Martinique - Pierre Zobda-Quitman Hospital, Fort-de-France 97261, MartiniqueTel +596 596 559769Email moustapha.drame@chu-martinique.frPurpose: The aim of this study was to investigate whether Chikungunya virus infection (CVI) was an independent risk factor for 2-year mortality in Afro-Caribbean subjects aged 65 years or older.Patients and methods: A retrospective cohort study was performed from January 2014 to December 2016 in the University Hospital of Martinique. Subjects aged ≥ 65 years admitted to the hospital were included. Baseline characteristics and concurrent manifestations at admission were collected. Subjects were followed up by phone for 2 years.Results: A total of 687 old Afro-Caribbean subjects (80.4± 8.0 years) were included: 467 positive for CVI (Chik+) and 220 negative for CVI (Chik-). During the follow-up, 180 (26.2%) died. The proportion of deaths was higher among Chik- (40.9%) than among Chik+ subjects (21.6%) (p< 0.0001). By multivariable analysis, when adjusted for age polyarthralgia, neurological troubles, cardiovascular disorders, absence of neutrophilia, thrombocytopenia, hypernatremia, and hospital stay, Chik+ subjects had significantly higher survival rates (HR: 0.58; 95% CI: 0.40– 0.85) than Chik- ones.Conclusion: Within the two years following hospital admission of subjects aged ≥ 65 years or older, Chik+ subjects had significantly higher survival rates than Chik- ones.Keywords: Chikungunya, survival, elderly people, hospital admission

Published
2020

13. Ovarian Fibrothecoma: A Case Report

Author

Keita, M, Traoré, B. Z, Dembélé, K. S, Kassogué, A, Samaké, B, M. A. Togo, A. N. Coulibaly, Koné, S. I, Dramé, M. B, Traoré, T, Coulibaly, D. S, Bagayoko, T. B, Sanogo, A, Kodio, A, Bah, A, and Toungara, H

Subjects
General Medicine
Abstract

Introduction: Fibrothecal group tumours are part of the gonadal stromal and sex cord tumours (GSST) and represent 1-4.7% of all organic ovarian tumours and are usually benign. We felt it important to report a case in order to share our experience in the management of fibrothecal tumours of the ovary. Observation: This was a 51-year-old postmenopausal patient who was referred to the hospital for abdominal pain in the context of an abdominal mass. A clinical examination and abdominal ultrasound concluded that the left ovarian tumour was benign. A left annecxectomy was performed and the histological examination concluded that the tumour was benign. No tumour marker was measured and no CT scan was performed. The postoperative course was simple and the patient was followed for 3 months.

Published
2023

16. Ovarian Fibrothecoma: A Case Report

Author

M, Keita,, primary, Z, Traoré, B., additional, S, Dembélé, K., additional, A, Kassogué,, additional, B, Samaké,, additional, Togo, M. A., additional, Coulibaly, A. N., additional, I, Koné, S., additional, B, Dramé, M., additional, T, Traoré,, additional, S, Coulibaly, D., additional, B, Bagayoko, T., additional, A, Sanogo,, additional, A,, Kodio,, additional, A, Bah,, additional, and H, Toungara,, additional

Published
2023
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23. Appendicular Mucocele about a Case at Nianankoro Fomba Hospital in Ségou

Author

Samaké, Dr. Bréhima, primary, Keita, M, additional, Togo, M A, additional, Coulibaly, A N, additional, Kassogué, A, additional, Dramé, M B, additional, Koné, SI, additional, Fofana, A, additional, Traoré, T, additional, Coulibaly, D S, additional, Bagayoko, T B, additional, Sanogo, A, additional, and Bah, A, additional

Published
2022
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30. POS1295 SYSTEMIC AND AUTO-INFLAMMATORY DISEASES OF PEDIATRIC ONSET: THE EXPERIENCE OF THE FRENCH OVERSEAS DEPARTMENTS OF AMERICA

Author

Felix, A., primary, Delion, F., additional, Coignard, E., additional, Martin, E., additional, Mohamed Sahnoun, M., additional, Hospice, C., additional, Cuadro Alvarez, E., additional, Elenga, N., additional, Dramé, M., additional, Bader-Meunier, B., additional, Deligny, C., additional, and Hatchuel, Y., additional

Published
2022
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35. Reverting the mode of action of the mitochondrial FOF1-ATPase by Legionella pneumophila preserves its replication niche

Author

Tobias Sahr, Platon L, Dramé M, Pedro Escoll, Carmen Buchrieser, Christophe Rusniok, Silke Schmidt, Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM), Université de Paris (UP), Collège doctoral [Sorbonne universités], Sorbonne Université (SU), This research was funded by the Institut Pasteur, DARRI - Institut Carnot - Microbe et santé (grant number INNOV-SP10-19) to PE, the Agence National de Recherche (grant number ANR-10-LABX- 62-IBEID) and the Fondation de la Recherché Médicale (FRM) (grant number EQU201903007847) to CB, and the Région Ile-de-France (program DIM1Health) to PBI (part of FranceBioImaging, ANR-10-INSB-04-01). MD was supported by the Ecole Doctorale FIRE – 'Programme Bettencourt'. SS was supported by the Pasteur Paris-University (PPU) International PhD Program., We acknowledge C.B.’s, P. Glaser’s lab members and F. Stavru at Institut Pasteur for fruitful discussions. We thank N. Aulner, A. Danckaert, Photonic BioImaging (PBI) UTechS and M. Hassan, Center for Translational Science (CRT) at Institut Pasteur, for support, ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Mémoires - Université de Montpellier - Faculté des sciences (UM FS), Faculté des sciences de Paris, Université de Paris (1896-1970), Collège Doctoral, This research was funded by the Institut Pasteur, DARRI-Institut Carnot-Microbe et santé (grant number INNOV-SP10-19) to PE, the Agence National de Recherche (grant number ANR-10-LABX-62-IBEID to CB and ANR-21-CE15-0038-01 to PE), the Fondation de la Recherché Médicale (FRM) (grant number EQU201903007847) to CB, and the Région Ile-de-France (program DIM1Health) to PBI (part of FranceBioImaging, ANR-10-INSB-04–01). MD was supported by the Ecole Doctorale FIRE – 'Programme Bettencourt.' SS was supported by the Pasteur Paris-University (PPU) International PhD Program., We acknowledge CB’s, P Glaser’s lab members, and F Stavru at Institut Pasteur for fruitful discussions. We specially thank Daniel Schator for help and discussions regarding HEK-293 infection and transfec- tion. We thank N Aulner, A Danckaert, Photonic BioImaging (PBI) UTechS and M Hassan, Center for Translational Science (CRT) at Institut Pasteur, for support., ANR-21-CE15-0038,MITOBAC,Interactions Métaboliques Hôte-Pathogène: Comment des Bactéries Intracellulaires détournent l'OXPHOS Mitochondriale pendant l'infection(2021), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), and Université Paris Cité (UPCité)

Subjects
Programmed cell death, QH301-705.5, MESH: Mitochondria, Science, infectious disease, FOF1-ATPase, Oxidative phosphorylation, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Legionella pneumophila, MESH: Proton-Translocating ATPases, 03 medical and health sciences, 0302 clinical medicine, mitochondrial membrane potential, MESH: Adenosine Triphosphate, Biology (General), MESH: Bacterial Proteins, MESH: Type IV Secretion Systems, 030304 developmental biology, Membrane potential, 0303 health sciences, Effector, microbiology, MESH: Mitochondrial Proteins, Metabolism, Microphthalmia-associated transcription factor, biology.organism_classification, MESH: Legionella pneumophila, OXPHOS, 3. Good health, Cell biology, macrophages, mitochondria, cell death, Medicine, Reprogramming, 030217 neurology & neurosurgery
Abstract

Legionella pneumophila, the causative agent of Legionnaires’ disease, a severe pneumonia, injects via a type-IV-secretion-system (T4SS) more than 300 proteins into macrophages, its main host cell in humans. Certain of these proteins are implicated in reprogramming the metabolism of infected cells by reducing mitochondrial oxidative phosphorylation (OXPHOS) early after infection. Here we show that despite reduced OXPHOS, the mitochondrial membrane potential (Δψm) is maintained during infection of primary human monocyte-derived macrophages (hMDMs). We reveal that L. pneumophila reverses the ATP-synthase activity of the mitochondrial FOF1-ATPase to ATP-hydrolase activity in a T4SS-dependent manner, which leads to a conservation of the Δψm, preserves mitochondrial polarization and prevents macrophage cell death. Analyses of T4SS effectors known to target mitochondrial functions revealed that LpSpl is partially involved in conserving the Δψm, but not LncP and MitF. The inhibition of the L. pneumophila-induced “reverse mode” of the FOF1-ATPase collapsed the Δψm and caused cell death in infected cells. Single-cell analyses suggested that bacterial replication occurs preferentially in hMDMs that conserved the Δψm and showed delayed cell death. This direct manipulation of the mode of activity of the FOF1-ATPase is a newly identified feature of L. pneumophila allowing to delay host cell death and thereby to preserve the bacterial replication niche during infection.

Published
2021

36. LA TOXOPLASMOSE CEREBRALE DANS LE SERVICE DE MALADIES INFECTIEUSES DU CHU DU POINT G CHEZ LES PERSONNES VIVANT AVEC LE VIH.

Author

Konaté, I., Sissoko, A. S., Cissoko, Y., Sogoba, D., A. G. Mohamed, M. A., Coulibaly, T. H., Soumaré, M., Magassoua, O., Fofana, A., Hassana, S., Coulibaly, T., Sacko, M., Koné, Z., Djimdé, S. O., Bagayoko, I., Dramé, M., Guinto, C. O., and Dao, S.

Abstract

Copyright of Mali Médical is the property of Mali Medical, Faculte de Medecine, de Pharmacie et d'Odonto-stomatologie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

45. 17-3 - La dénutrition et ses facteurs associés en famille d'accueil pour personnes âgées, Guadeloupe

Author

Boucaud-Maitre, D., Simo-Tabué, N., Mounsamy, L., Letchimy, L., Dramé, M., and Tabué-Teguo, M.

Abstract

La famille d'accueil pour personnes âgées dépendantes pourrait être un modèle d'hébergement intéressant, particulièrement pour les pays qui n'ont pas ou ne souhaitent pas développer des Ehpad (Etablissement d'hébergement pour personnes âgées dépendantes). L'objectif de cette étude était d’évaluer la fréquence de la dénutrition et ses facteurs associés des personnes âgées en famille d'accueil en Guadeloupe.

Published
2024
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46. Les auteurs

Author

Dramé, M., Epstein, J., Noëlle, H., Agrinier, N., Astagneau, P., Auquier, P., Bahrami, S., Bastuji-Garin, S., Bellier, A., Berbis, J., Bongard, V., Bouaud, J., Bouchard, F., Boussat, B., Bouzille, G., Burgun, A., Chazard, E., Claudot, F., Cossin, S., Cuggia, M., Dananché, C., Darmoni, S., Dauchet, L., Deboscker, S., Dechartres, A., Delbos, L., Delva, F., de Souza, S., Dezetrée, A., Dhalluin, T., Duclos, A., Dufour, J.-C., Ferrières, J., Ficheur, G., François, P., Gauthier, V., Gignon, M., Grammatico-Guillon, L., Halley des Fontaines, V., Josseran, L., Kivits, J., Labarère, J., Lacour, B., Lasset, C., Lavigne, T., Le Douarin, Y.-M., Le Faou, A.-L., Leclère, B., Lerner, I., Migeot, V., Moreau-Gaudry, A., Moret, L., Neuraz, A., Pihouee, L., Quantin, C., Rance, B., Richard, F., Riou, C., Rollier, S., Seigneurin, A., Seroussi, B., Simon-Tillaux, N., Staccini, P., Sylvestre, E., Tsopra, R., Vanhems, P., Velten, M., Vidal-Trécan, G., Viel, J.-F., and Viprey, M.

Published
2022
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