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39 results on '"Draghini, Lorena"'

1. Ladies project: large database in endometrial cancers for a personalized treatment

Author

Autorino, Rosa, Rinaldi, Raffaella Michela, Macchia, Gabriella, Boccardi, Mariangela, Mihoci Roshanian, Inga, Sebastiani, Rita, Santo, Bianca, Russo, Donatella, Ferioli, Martina, Benini, Anna, Perrucci, Elisabetta, Raguso, Arcangela, Cossa, Sabrina, Matteucci, Paolo, Talocco, Claudia, Vicenzi, Lisa, Trippa, Fabio, Draghini, Lorena, Augurio, Antonietta, Di Guglielmo, Fiorella Cristina, Cocuzza, Paola, Pistis, Francesca, De Felice, Francesca, Meregalli, Sofia, Bonetto, Elisa Maria, Tamburo, Maria, Bini, Vittorio, Vavassori, Andrea, Gambacorta, Maria Antonietta, and Aristei, Cynthia

Published
2024
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3. Stereotactic Ablative Radiation Therapy for Oligometastatic Ovarian Cancer Lymph Node Disease: The MITO-RT3/RAD Phase II Trial

Author

Macchia, Gabriella, Campitelli, Maura, Pezzulla, Donato, Lucci, Simona, Fodor, Andrei, Russo, Donatella, Balcet, Vittoria, Bonome, Paolo, Durante, Stefano, Draghini, Lorena, Titone, Francesca, D'Agostino, Giuseppe Roberto, Tamburo, Marinella, Ferioli, Martina, Ippolito, Edy, Tortoreto, Francesca, Caravatta, Luciana, De Felice, Francesca, Stefano, Aida Di, Fanelli, Mara, Cilla, Savino, Cosentino, Francesco, Marchetti, Claudia, Salutari, Vanda, Boccia, Serena, Morganti, Alessio Giuseppe, Gambacorta, Maria Antonietta, Fagotti, Anna, Pignata, Sandro, Scambia, Giovanni, Ferrandina, Gabriella, and Deodato, Francesco

Published
2025
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4. Efficacy of stereotactic body radiotherapy and response prediction using artificial intelligence in oligometastatic gynaecologic cancer

Author

Macchia, Gabriella, Cilla, Savino, Pezzulla, Donato, Campitelli, Maura, Laliscia, Concetta, Lazzari, Roberta, Draghini, Lorena, Fodor, Andrei, D'Agostino, Giuseppe R., Russo, Donatella, Balcet, Vittoria, Ferioli, Martina, Vicenzi, Lisa, Raguso, Arcangela, Di Cataldo, Vanessa, Perrucci, Elisabetta, Borghesi, Simona, Ippolito, Edy, Gentile, Piercarlo, De Sanctis, Vitaliana, Titone, Francesca, Delle Curti, Clelia Teresa, Huscher, Alessandra, Gambacorta, Maria Antonietta, Ferrandina, Gabriella, Morganti, Alessio G., and Deodato, Francesco

Published
2024
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5. Stereotactic body radiotherapy in oligometastatic cervical cancer (MITO-RT2/RAD study): a collaboration of MITO, AIRO GYN, and MaNGO groups

Author

Macchia, Gabriella, Nardangeli, Alessia, Laliscia, Concetta, Fodor, Andrei, Draghini, Lorena, Gentile, Pier Carlo, D’Agostino, Giuseppe Roberto, Balcet, Vittoria, Bonome, Paolo, Ferioli, Martina, Autorino, Rosa, Vicenzi, Lisa, Raguso, Arcangela, Borghesi, Simona, Ippolito, Edy, Di Cataldo, Vanessa, Cilla, Savino, Perrucci, Elisabetta, Campitelli, Maura, Gambacorta, Maria Antonietta, Deodato, Francesco, Scambia, Giovanni, and Ferrandina, Gabriella

Published
2022
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10. Re-irradiation for recurrent glioma: outcome evaluation, toxicity and prognostic factors assessment. A multicenter study of the Radiation Oncology Italian Association (AIRO)

Author

Navarria, Pierina, Minniti, Giuseppe, Clerici, Elena, Tomatis, Stefano, Pinzi, Valentina, Ciammella, Patrizia, Galaverni, Marco, Amelio, Dante, Scartoni, Daniele, Scoccianti, Silvia, Krengli, Marco, Masini, Laura, Draghini, Lorena, Maranzano, Ernesto, Borzillo, Valentina, Muto, Paolo, Ferrarese, Fabio, Fariselli, Laura, Livi, Lorenzo, Pasqualetti, Francesco, Fiorentino, Alba, Alongi, Filippo, di Monale, Michela Buglione, Magrini, Stefano, and Scorsetti, Marta

Published
2019
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11. 1313: A multi-center study on the role of radiotherapy in early stage extranodal indolent lymphomas

Author

Bartoncini, Sara, Ciammella, Patrizia, Casale, Chiara, Buglione, Michela, Cavallin, Chiara, Guerini, Andrea, Vianello, Federica, Talomo, Sara, Alì, Emanuele, Di Russo, Anna, Matrone, Fabio, Donofrio, Alessandra, De Felice, Francesca, De Sanctis, Vitaliana, De Cumis, Ilenia Iamundo, Moschini, Ilaria, Montesi, Giampaolo, Draghini, Lorena, Reali, Alessia, Clot, Francesca, Ricardi, Umberto, and Levis, Mario

Published
2024
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12. 603: SBRT and artificial intelligence in oligometastatic GYN-cancers: a real-world study.

Author

Macchia, Gabriella, Cilla, Savino, Pezzulla, Donato, Campitelli, Maura, Laliscia, Concetta, Lazzari, Roberta, Draghini, Lorena, Fodor, Andrei, D'Agostino, Giuseppe, Russo, Donatella, Balcet, Vittoria, Ferioli, Martina, Vicenzi, Lisa, Raguso, Arcangela, Di Cataldo, Vanessa, Epifani, Valeria, Borghesi, Simona, Di Stefano, Aida, Ippolito, Edy, De Sanctis, Vitaliana, Titone, Francesca, Curti, Clelia Teresa Delle, Huscher, Alessandra, Ferrandina, Gabriella, and Deodato, Francesco

Published
2024
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13. Efficacy and Safety of Stereotactic Body Radiation Therapy in Oligometastatic Uterine Cancer (MITO-RT2/RAD): A Large, Real-World Study in Collaboration With Italian Association of Radiation Oncology, Multicenter Italian Trials in Ovarian Cancer, and Mario Negri Gynecologic Oncology Group Groups

Author

Macchia, Gabriella, primary, Pezzulla, Donato, additional, Campitelli, Maura, additional, Laliscia, Concetta, additional, Fodor, Andrei, additional, Bonome, Paolo, additional, Draghini, Lorena, additional, Ippolito, Edy, additional, De Sanctis, Vitaliana, additional, Ferioli, Martina, additional, Titone, Francesca, additional, Balcet, Vittoria, additional, Di Cataldo, Vanessa, additional, Russo, Donatella, additional, Vicenzi, Lisa, additional, Cossa, Sabrina, additional, Lucci, Simona, additional, Cilla, Savino, additional, Deodato, Francesco, additional, Gambacorta, Maria Antonietta, additional, Scambia, Giovanni, additional, Morganti, Alessio Giuseppe, additional, and Ferrandina, Gabriella, additional

Published
2023
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14. EFFICACY AND SAFETY OF STEREOTACTIC BODY RADIOTHERAPY (SBRT) IN OLIGOMETASTATIC UTERINE CANCER (MITO-RT2/RAD STUDY): A LARGE, REAL-WORLD STUDY IN COLLABORATION WITH AIRO GYN, MITO and MaNGO Groups

Author

Macchia, Gabriella, Pezzulla, Donato, Campitelli, Maura, Laliscia, Concetta, Fodor, Andrei, Bonome, Paolo, Draghini, Lorena, Ippolito, Edy, Sanctis, Vitaliana DE, Ferioli, Martina, Titone, Francesca, Balcet, Vittoria, Cataldo, Vanessa DI, Russo, Donatella, Vicenzi, Lisa, Cossa, Sabrina, Lucci, Simona, Cilla, Savino, Deodato, Francesco, Gambacorta, Maria Antonietta, Scambia, Giovanni, Morganti, Alessio Giuseppe, Ferrandina, Maria Gabriella, Deodato, Francesco (ORCID:0000-0003-1276-5070), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Scambia, Giovanni (ORCID:0000-0003-2758-1063), Ferrandina, Gabriella (ORCID:0000-0003-4672-4197), Macchia, Gabriella, Pezzulla, Donato, Campitelli, Maura, Laliscia, Concetta, Fodor, Andrei, Bonome, Paolo, Draghini, Lorena, Ippolito, Edy, Sanctis, Vitaliana DE, Ferioli, Martina, Titone, Francesca, Balcet, Vittoria, Cataldo, Vanessa DI, Russo, Donatella, Vicenzi, Lisa, Cossa, Sabrina, Lucci, Simona, Cilla, Savino, Deodato, Francesco, Gambacorta, Maria Antonietta, Scambia, Giovanni, Morganti, Alessio Giuseppe, Ferrandina, Maria Gabriella, Deodato, Francesco (ORCID:0000-0003-1276-5070), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Scambia, Giovanni (ORCID:0000-0003-2758-1063), and Ferrandina, Gabriella (ORCID:0000-0003-4672-4197)

Abstract

Objective: This retrospective, multicenter study analyzes the efficacy and safety of stereotactic body radiotherapy in a large cohort of oligometastatic/persistent/recurrent uterine cancer patients. Methods: Clinical and radiotherapy data from several radiotherapy centers treating patients by stereotactic body radiotherapy between March 2006 and October 2021 were collected. Objective response rate was defined as complete and partial response, while clinical benefit included objective response rate plus stable disease. Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer and Common Terminology Criteria for Adverse Events scales were used to grade toxicities. Primary endpoints were the rate of complete response to stereotactic body radiotherapy, and the 2-year actuarial local control rate 'per-lesion' basis. Secondary endpoints were progression-free survival and overall survival, as well as toxicity. Results: 157 oligometastatic/persistent/recurrent uterine cancer patients bearing 272 lesions treated by stereotactic body radiotherapy at 14 centers were analyzed. Lymph node metastases (137, 50.4%) were prevalent, followed by parenchyma lesions (135, 49.6%). Median total dose was 35 Gy (10-75.2), in five fractions (range 1-10). Complete and partial responses were 174 (64.0%), and 54 (19.9%), respectively. Stable disease was registered in 29 (10.6%), while 15 (5.5%) lesions progressed. Type of lesion (lymph node), volume (≤ 13.7 cc) and total dose (BED10 >59.5 Gy) were significantly associated with a higher probability of achieving complete response. Patients achieving complete response (CR) 'per-lesion' basis experienced a 2-year actuarial local control rate of 92.4% versus 33.5% in lesions not achieving complete response (NCR) (p<0.001). Moreover, the 2-year actuarial progression-free survival rate in patients with CR was 45.4%, while patients with NCR had a 2-year rate of 17.6% (p value: <0.001). Finally, patients who ha

Published
2023

15. Vaginal Toxicity Management in Patients with Locally Advanced Cervical Cancer following Exclusive Chemoradiation—A Nationwide Survey on Knowledge and Attitudes by the Italian Association of Radiotherapy and Clinical Oncology (AIRO) Gynecology Study Group

Author

De Felice, Francesca, primary, Vicenzi, Lisa, additional, Macchia, Gabriella, additional, Vavassori, Andrea, additional, Perrucci, Elisabetta, additional, Cerrotta, Annamaria, additional, Lancellotta, Valentina, additional, Meregalli, Sofia, additional, Draghini, Lorena, additional, Augurio, Antonietta, additional, and De Sanctis, Vitaliana, additional

Published
2023
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18. An Italian survey on “palliative intent” radiotherapy

Author

Pergolizzi, Stefano, primary, Cacciola, Alberto, additional, Parisi, Silvana, additional, Lillo, Sara, additional, Tamburella, Consuelo, additional, Santacaterina, Anna, additional, Ferini, Gianluca, additional, Cellini, Francesco, additional, Draghini, Lorena, additional, Trippa, Fabio, additional, Arcidiacono, Fabio, additional, and Maranzano, Ernesto, additional

Published
2022
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19. 1982: LADIES Project: Large Database In Endometrial cancers for a personalized treatment

Author

Rinaldi, Raffaella Michela, Autorino, Rosa, Vavassori, Andrea, Macchia, Gabriella, Boccardi, Mariangela, Roshanian, Inga Mihoci, Santo, Bianca, Ferioli, Martina, Perrucci, Elisabetta, Raguso, Arcangela, Matteucci, Paolo, Draghini, Lorena, Augurio, Antonietta, Cocuzza, Paola, Vicenzi, Lisa, Pistis, Francesca, De Felice, Francesca, Meregalli, Sofia, Tamburo, Maria, Gambacorta, Maria Antonietta, and Aristei, Cynthia

Published
2024
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21. 600: Radiation therapy in Non-Melanoma Skin Cancer (NMSC): an Italian survey on behalf of AIRO

Author

Pezzulla, Donato, Pastore, Francesco, Fionda, Bruno, Di Franco, Rossella, Ciabattoni, Antonella, Corazzi, Francesca, Cossa, Sabrina, Dominici, Luca, Draghini, Lorena, Gherardi, Federica, Lillo, Sara, Longo, Silvia, Cellini, Francesco, Mazzarotto, Renzo, navarria, Federico, Piccolo, Federica, Stefanelli, Antonio, Vicenzi, Lisa, Zamagni, Alice, Maranzano, Ernesto, and Tagliaferri, Luca

Published
2024
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22. Stereotactic radiotherapy for lung oligometastases

Author

Falcinelli, Lorenzo, primary, Menichelli, Claudia, additional, Casamassima, Franco, additional, Aristei, Cynthia, additional, Borghesi, Simona, additional, Ingrosso, Gianluca, additional, Draghini, Lorena, additional, Tagliagambe, Angiolo, additional, Badellino, Serena, additional, and Buglione di Monale e Bastia, Michela, additional

Published
2022
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28. Stereotactic Body Radiotherapy in Contralateral Kidney Oligometastasis From Renal Cell Carcinoma in a Nephrectomized Patient.

Author

Di Marzo, Alessandro, Casale, Michelina, Trippa, Fabio, Anselmo, Paola, Arcidiacono, Fabio, Draghini, Lorena, Terenzi, Sara, and Maranzano, Ernesto

Subjects
RENAL cell carcinoma, STEREOTACTIC radiotherapy, MAGNETIC resonance imaging, KIDNEYS, TREATMENT effectiveness, DIAGNOSIS
Abstract

Background: Renal cell carcinoma (RCC) frequently metastasizes to distal organs such as the lungs, abdomen, bones, and brain. Although rare cases of adrenal gland metastasis from RCC have been described, to our knowledge, no cases have reported the use of stereotactic body radiotherapy (SBRT) in contralateral kidney oligometastasis in a nephrectomized patient with RCC. Case Report: We report a rare case of single contralateral renal metastasis from RCC in a 65-year-old female that occurred 1 year after right radical nephrectomy. At diagnosis of relapse, the patient received targeted therapy with sunitinib for 9 consecutive months, resulting in a partial regression of renal metastasis. To preserve the organ and consolidate response, SBRT was administered to the residual mass. Targeted therapy was temporarily discontinued 15 days before and after SBRT. Total SBRT dose was 40 Gy in 5 daily fractions given with volumetric modulated arc and image-guided technique. Three months later, magnetic resonance imaging documented a complete regression of disease, a result that persisted at the last follow-up 19 months after SBRT. Conclusion: The combination of sequential targeted therapy and SBRT provided an excellent outcome in a patient with a solitary kidney who experienced contralateral kidney metastasis from RCC. This treatment approach was well tolerated and controlled the disease. [ABSTRACT FROM AUTHOR]

Published
2021
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30. Re-irradiation for recurrent glioma: outcome evaluation, toxicity and prognostic factors assessment. A multicenter study of the Radiation Oncology Italian Association (AIRO)

Author

Navarria, Pierina, primary, Minniti, Giuseppe, additional, Clerici, Elena, additional, Tomatis, Stefano, additional, Pinzi, Valentina, additional, Ciammella, Patrizia, additional, Galaverni, Marco, additional, Amelio, Dante, additional, Scartoni, Daniele, additional, Scoccianti, Silvia, additional, Krengli, Marco, additional, Masini, Laura, additional, Draghini, Lorena, additional, Maranzano, Ernesto, additional, Borzillo, Valentina, additional, Muto, Paolo, additional, Ferrarese, Fabio, additional, Fariselli, Laura, additional, Livi, Lorenzo, additional, Pasqualetti, Francesco, additional, Fiorentino, Alba, additional, Alongi, Filippo, additional, di Monale, Michela Buglione, additional, Magrini, Stefano, additional, and Scorsetti, Marta, additional

Published
2018
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31. Lung reirradiation with stereotactic body radiotherapy

Author

Maranzano, Ernesto, Draghini, Lorena, Anselmo, Paola, Casale, Michelina, Arcidiacono, Fabio, Chirico, Luigia, Italiani, Marco, and Trippa, Fabio

Subjects
Clinical Investigation
Abstract

We examined safety and efficacy of stereotactic body radiotherapy (SBRT) in reirradiation for lung recurrent lesions (LRLs).Eighteen patients, 4 with lung local failure from primary non-small cell lung carcinomas and 14 with lung metastases, were reirradiated with SBRT for 29 LRLs. Doses were recalculated to an Equivalent Dose of 2 Gy per fraction (EQDPeripherally located lesions received 5 fractions of 8-10 Gy, while centrally ones lower doses (5 fractions of 5-8 Gy). Cumulative EQDReirradiation of LRLs with SBRT was feasible and effective. It is important to appropriately select patient and to adopt organ at risk constrains considering cumulative doses.

Published
2016

32. Zwölfjahresergebnisse der LINAC-basierten Radiochirurgie für Vestibularisschwannome.

Author

Anselmo, Paola, Casale, Michelina, Arcidiacono, Fabio, Trippa, Fabio, Rispoli, Rossella, Draghini, Lorena, Terenzi, Sara, Di Marzo, Alessandro, and Maranzano, Ernesto

Abstract

Copyright of Strahlentherapie und Onkologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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34. Stereotactic body radiotherapy in oligometastatic prostate cancer patients with isolated lymph nodes involvement: a two-institution experience

Author

Ingrosso, Gianluca, primary, Trippa, Fabio, additional, Maranzano, Ernesto, additional, Carosi, Alessandra, additional, Ponti, Elisabetta, additional, Arcidiacono, Fabio, additional, Draghini, Lorena, additional, Di Murro, Luana, additional, Lancia, Andrea, additional, and Santoni, Riccardo, additional

Published
2016
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38. Low and medium doses of hypofractionated stereotactic radiotherapy could be suboptimal for early-stage lung cancer.

Author

Maranzano, Ernesto, Draghini, Lorena, Rossi, Romina, Casale, Michelina, and Trippa, Fabio

Subjects
*STEREOTACTIC radiotherapy, *CANCER radiotherapy research, *LUNG cancer treatment, *IONIZING radiation dosage, *CANCER treatment
Abstract

Purpose: This study aimed to analyze the outcome of low and medium doses of hypofractionated stereotactic body radiotherapy (SBRT) in early stage lung cancer. Methods: Thirty-five early stage lung cancer patients were treated with SBRT. Initially, SBRT was administered with a low dose of 5 x 8Gy in all cases. Subsequently, a medium dose of 5 x 10Gy for peripherally located lesions was given, continuing to prescribe 5 x 8Gy in centrally located ones. Study endpoints were local control (LC), LC duration, survival and toxicity. Results: Patients had a good performance status, and T1-2 stage cancer. The SBRT doses of 5 x 8Gy and 5 x 10Gy were administered to 57% and 43% of patients, respectively. At first evaluation after SBRT, local control was obtained in all cases but only 15 (43%) had a complete response. Median duration of LC was 41 months and there was a trend in favor of 5 x 10Gy with respect to 5 x 8Gy in 2- and 3-year LC rates (93% and 69%, versus 60% and 50%, p = 0.1). Four of the 15 (27%) complete responders had local relapse after a quite long median time of 31.5 months. Median overall survival was 40 months. No examined variables (i.e., dose, volume, T stage, and site) significantly conditioned LC, duration of LC, failure rate and survival. Both SBRT schedules were well tolerated. Conclusion: Outcome of low and medium SBRT doses in terms of LC, duration of LC, patterns of failure and survival was suboptimal compared with recently reported results of SBRT in early stage lung cancer patients. [ABSTRACT FROM AUTHOR]

Published
2013

39. Lung reirradiation with stereotactic body radiotherapy.

Author

Maranzano E, Draghini L, Anselmo P, Casale M, Arcidiacono F, Chirico L, Italiani M, and Trippa F

Abstract

Purpose: We examined safety and efficacy of stereotactic body radiotherapy (SBRT) in reirradiation for lung recurrent lesions (LRLs)., Materials and Methods: Eighteen patients, 4 with lung local failure from primary non-small cell lung carcinomas and 14 with lung metastases, were reirradiated with SBRT for 29 LRLs. Doses were recalculated to an Equivalent Dose of 2 Gy per fraction (EQD 2 ) and α/β ratio was assumed to be Gy 10 for primary and metastatic lung tumors and Gy 3 for organ at risk. Cumulative administered doses were calculated adding doses of prior radiotherapy and reirradiation., Results: Peripherally located lesions received 5 fractions of 8-10 Gy, while centrally ones lower doses (5 fractions of 5-8 Gy). Cumulative EQD 2 did not exceed 198 Gy 10 and reirradiated volumes were rather small (median 18 cc). Local control was obtained for all patients except one and lasted medially 43 months. Median overall survival was 40 months from reirradiation. Only acute grade 1 toxicity was recorded., Conclusions: Reirradiation of LRLs with SBRT was feasible and effective. It is important to appropriately select patient and to adopt organ at risk constrains considering cumulative doses., Competing Interests: Authors’ disclosure of potential conflicts of interest The authors reported no conflict of interest.

Published
2016

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