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In biomedical engineering, fiber-reinforced polymers play an important role in creating physical biological models of patients, which helps surgeons explain anatomical details to patients and perform trial operations. Replicating the precise three-dimensional (3D) structure of the human mandible is now a priority for rebuilding these bones for complete functional and aesthetic healing. Additional production methods and reverse engineering are required to achieve the design of a personalized device with precise shape and size. The main purpose of this research work is to develop a specially developed human mandibular biological model using the additive manufacturing method, FDM (Fused Deposition Melting). FDM is performed by loading a CAD model into a 3D Printer. We present this method using the FDM (Fused Deposition Melting) method to generate a human mandible biological model. Data obtained from computed tomography (CT) with a resolution of 1 mm was converted to a 3D model by computer aided design (CAD) using CT digital imaging and medical communication (DICOM) data. After the CAD model is built, it is converted to a stereolithography (*.STL) format and then processed by rapid prototyping techniques to create a physical anatomical model using 3D printing. Converting two-dimensional data (2D) from computed tomography data to a 3D model is an accurate guide to shaping bone grafts. The current approach can translate treatment plans directly into the surgical field. It is an important teaching tool for forming and fixing implants, helping to counsel patients.