Search

Your search keyword '"Doyle, J S"' showing total 122 results
Start Over Author "Doyle, J S"
122 results on '"Doyle, J S"'

6. Irish society of Gastroenterology: Proceedings of summer meeting, boole auditorium, university college, cork on friday 27th and saturday 28th may, 1988.

Author

Murray, D. P., Foley, R., Whelton, M. J., Moriarty, K. J., Brooks, S., Loft, D., Mpoko, N., Gardner, V., Marsh, M. N., Stevens, Fiona M., Kearns, M., Moran, B., Sutton, G., Taylor, M., Karran, S. J., Courtney, M. G., O’Brien, M., McPartlin, J. M., Gibney, M. J., Scott, J. M., Weir, D. G., Suzuki, Y., Tobin, A., Quinn, D., Whelan, A., O’Morain, A., Waldron, R., O’Riordan, M., Kirwan, W. O., Ryan, T., Lennon, J., Crowe, J., Shinkwin, C., Kirwan, W., Mackle, E. J., Parks, T. G., O’Keefe, L., Lanigan, D., O’Donnell, M., Harte, P., O’Sullivan, G., Foley, D. P., Dunne, P., Dervan, P., Crowe, J. P., O’Callaghan, T., Chua, A., Kennedy, N. P., MacMathuna, P., Keating, J. J., Weir, D. G., Keeling, P. W. N., Leen, E., McKenna, D., Gilligan, D., Ward, R., Casey, E., Tobin, A., Hutchinson, L., Sweeney, E. C., O’Morain, C., Collins, J. S. A., Sloan, J. M., Watt, P. H., Hamilton, P. W., Love, A. H. G., Chua, A., Kennedy, N. P., MacMathuna, P., Keating, J. J., Maxwell, W. J., Brennan, D. P., Huang, J., McDonald, G., Weir, D. G., Keeling, P. W. N., Brennan, D. P., Kennedy, N. P., Keeling, P. W. N., McKenna, D., Ward, R., Gilligan, D., Tobin, A., Sweeney, E. C., O’Morain, C., Ryan, T., Lennon, J., Crowe, J., Diamond, T., Rowlands, B. J., Keating, J., O’Reilly, E., Burke, P., McDonald, G. S. A., Monson, J., Stephens, R., Corrigan, O., Keeling, P. W. N., Carey, P. D., Darzi, A., Monson, J. R. T., O’Morain, C., Tanner, W. A., Keane, F. B. V., Darzi, A., Monson, J. R. T., Carey, P. D., O’Morain, C., Tanner, W. A., Keane, F. B. V., Rogers, E., McAnena, O. J., Given, H. F., Keeling, P., O’Sullivan, G., DeMeester, T., Skinner, David B., Collins, J. K., O’Sullivan, G., O’Donoghue, M., O’Brien, F., O’Donovan, T., Corbett, A., Hahnvaganawong, C., Nolan, S., Collins, J., O’Sullivan, G., Murray, J., Hogan, B., Sullivan, M., Doyle, J. S., Butler, P., Walker, F., Murray, J., Doyle, J. S., O’Dwyer, P. J., Minton, J., Enright, H., Patchett, S., O’Connell, L., O’Donoghue, D. P., Afdhal, N. H., Collins, J. S. A., Cattey, R. P., Hogan, W. J., Helm, J. F., Ash, R., O’Briain, D. S., O’Malley, F., and Courtney, G.

Published
1991
Full Text
View/download PDF

8. Irish society of gastroenterology: Proceedings of Winter Meeting held 4th/5th December 1992in Beaumont hospital, Dublin

Author

O’Sullivan, M., Thornton, G., O’Sullivan, G., O’Mahony, A. M., O’Connell, J., Hanvajanawong, C., Phelan, D., O’Sullivan, G. C., Collins, J. K., Bamford, K. B., Lutton, D. A., Collins, J. S. A., O’Loughlin, B., Johnston, B. T., McFarland, R. J., Love, A. H. G., Buchanan, K. D., Fillmore, D., Ardill, J. E. S., Clyne, M., Drumm, B., Cyne, M., Tham, T. C. K., McLaughlin, N., Hughes, D. F., Ferguson, M., Crosbie, J. J., Madden, M., Namnyak, S., O’Connor, F. A., Magbri, Awad El, Stevens, F. M., McCarthy, C. F., Lynch, M., O’Brien, M., Ryan, E., MacMathuna, P., Kelly, P., Lennon, J., Crowe, J., Mulvey, S., Maguire, C., Clarke, E., Cronin, K. J., Kent, P., Mooney, E., Corrigan, T., O’Connell, R., Fitzpatrick, J. M., Gorey, T. F., Prabhaker, M. C., Bannon, C. A., Delaney, C., Duggan, M., Gorey, T., Abuzakouk, M., Lynch, S., Casey, E., Weir, D., Feighery, C., O’Farrelly, C., Fan, X. J., Chua, A., Shahi, C. N., Kelleher, D., Keeling, P. W. N., Parks, R. W., Diamond, T., McCrory, D. C., Johnston, G. W., Clements, W. D. B., Ennis, M., Campbell, G. R., Halliday, M. I., Rowlands, B. J., Wilson, R. H., Williamson, K., McLoughlin, J., Moorehead, R. J., O’Connor, A. M., Johnston, C. F., Gillmore, D., Boreham, C., Caldwell, M. T. P., Jazrawi, S., Byrne, P. J., Walsh, T. N., Hennessy, T. P. J., Li, H., Kay, E. W., Mulcahy, H., Curran, B., O’Donoghue, D., Leader, M., Walsh, C. Barry, O’Sullivan, S. T., Reardon, C. M., Hardiman, C., O’Donnell, J. A., Kirwan, W. O., Brady, M. P., McGreal, G., Hehir, D. J., Brady, M. P., O’Donnell, J., Pender, S. M., Courtney, M. G., Fielding, J. F., Swan, N., Chong, A., Denesh, T. G., Coll, D., McElearney, C., Kay, E., Sant, S., Doyle, J. S., Buckley, M., Cahill, R. J., Beattie, S., Hamilton, H., O’Morain, C., O’Sullivan, K., Forde, A. M., Gilvarry, J., Jackson, J., Alvi, R., Leahy, A., Lynch, G., Lane, B., Browne, H. Y., Keeling, P., Stafford-Johnson, D., Kee, S., Carr, J., Ryan, M. J., Sheehan, S., Broe, P., Deasy, J., O’Donovan, D. A., Bouchier-Hayes, D. M., Kelly, C., Grace, P., Redmond, H. P, Burke, P., Bouchier-Hayes, D. J., O’Malley, K., Qureshi, A., Osborne, H., Monkhouse, W. S., Bouchier-Hayes, D., Goggin, M., Joyce, W. P., Traynor, O., Hyland, J., Beausang, E., Mealy, K., Prendergast, C., Joyce, L., McNicholas, M. M. J., Gibney, R. G., Dolan, J., MacErlean, D. P., Hyland, J. M., Fenlon, H. M., Mulcahy, H. E., Stack, W. A., Skelly, M. M., Hegarty, J. E., Stack, W., O’Donoghue, D. P., Norris, S. M., McNicholas, M., Murray, F. E., Williams, N., Burke, J., Lamort, W., Fitzpatrick, J., Afdhal, N., Gibney, R., McLoughlin, R. F., Mourad, F. H., O’Donnell, L. J. D., Dias, J., Ogutu, E., Farthing, M. J. G., Hoyle, C. H. V., Hill, A. D. K., Darzi, A., Carey, P. D., Menzies-Gow, N., Monson, J. R. T., Goggins, M. G., O’Broin, S., Kelleher, B., Scott, J. M., Weir, D. D., Watson, R. G. P., Goss, B., Angus, P. W., Duckham, N., Sewell, R. B., and Smallwood, R. A.

Published
1993
Full Text
View/download PDF

9. Irish society of gastroenterology: Proceedings of Spring Meeting, University College, Galway on Friday 9th and Saturday 10th June, 1989.

Author

Fitzgerald, E. J., Chua, A., Clabby, C., Keeling, P. W. N., Gilvarry, J. M., Keeling, F., Fitzgerald, O., Fielding, J. F., Mathai, Elizabeth, O’Riordan, T., Tobin, A., Beattie, S., Cafferkey, M., Keane, C. T., O’Morain, C., O’Dwyer, P. J., Hassan, A., Murphy, J. J., Higgins, N. J., Kelly, D., McEntee, G. P., McGeeney, K. F., Fitzpatrick, J. M., Halpin, D. P., O’Byme, P. M., McEntee, G., Hermessy, T. P., Stephens, R. B., Hurley, J. P., Keeling, P., Hurley, J. P., Keeling, P., O’Brien, S., Keoghan, M., Afdhal, N., Hegarty, J. E., Burke, P., Sharp, M., Traynor, O., Molloy, R. G., O’Riordan, M. G., Gillen, P., Kirwan, W. O., Mathai, E., Beattie, S., Cafferkey, M., Keane, T., O’Morain, C., Byrne, P. T., Stuart, R., Lawlor, P., O’Sullivan, G., Hennessy, T. P. J., Burke, P., Hourihane, J., Stephens, R., Mullan, F. J., Campbell, G. R., Rowlands, J., McKelvey, S. T. D., Mullan, F. I., Wilson, H. K., Majury, W., Mills, J., Cromie, A. J., McKelvey, S. T. D., Kerin, M. J., O’Farrell, D., Waldron, R. P., Johnson, J. G., Trimble, K. C., Nunes, D. P., Courtney, M. G., Pomeroy, L., Shattock, A. G., Mulcahy, F. M., Weir, D. G., Chua, A., Ah-Kion, S., Noonan, N., Murphy, J., Weir, D. G., McNulty, J., O’Brien, S., Keoghan, M., Casey, M., Fitzgerald, M. X., Hegarty, J. E., Waldon, B., Cullen, P. T., Hopwood, D., Sutton, D., Kennedy, N., Campbell, F. C., MacMahon, N., Hogan, B., Murray, J., Doyle, J. S., Courtney, M. G., Deasy, J. M., Carr, J., Bouchier-Hayes, C., Cleary, A. P., Walsh, T. N., Gawley, W. F., O’Byrne, P. M., Gleeson, M. I., Calthorpe, D. T., Lane, B. E., Walsh, T. N., Heffernan, S. J., Sanfey, H., Steer, J., Cottell, D., Steer, M., Traynor, O., McEntee, G. P., Stuart, R., Gorey, T. F., Nolan, N., Byme, P., Lawlor, P., Hennessy, T. P. J., Gorey, T. F., Stewart, R., Gillen, P., Nolan, E., Jones, E., McEntee, G., Hennessy, T. P. J., MacMahon, M., Brennan, P., Carmody, E., Nizar, D., Walsh, T. N., Osbome, H., Courtney, M. G., O’Dwyer, R. L., Stevens, F., McCarthy, F., Deasy, J. M., Clery, A. P., Bouchier-Hayes, D., Crerand, S., Feeley, T. M., Waldron, R., Corrigan, T., Hederman, W., O’Cormell, F., Heffernan, S. J., Hurley, J. P., and Keeling, P.

Published
1991
Full Text
View/download PDF

10. Irish association of Rheumatology & Rehabilitation: Proceedings of the annual general meeting, friday, 16th november, 1990

Author

Etwebi, A. B., Comerford, F. R., Callaghan, Maire, Mulherin, D., Whelan, A., Feighery, C., FitzGerald, M. X., Bresnihan, B., Bell, A. L., Markey, G. M., Alexander, H. D., Morris, M., McNally, J. A., O’Byrne, S., Hall, M., Cuffe, J. T., Feely, J., Casey, E. B., de Paor, A., Reilly, R., Casey, Eoin, McCormack, B., Kearns, G., Beirne, C., Ryan, D., Kearns, G. D., Casey, E. B., Nuallain, E. M., Reen, D. J., Kelleher, D., Murphy, Anne, Feighery, C., Casey, E. B., Cullen, D., Kelleher, D., Murphy, A., Keams, G., Feighery, C., Casey, E. B., Foley-Nolan, D., Brady, A., Stack, J., Barry, C., Ennis, J., Coughlan, R. J., Foley-Nolan, D., Murray, P., Campbell, E., Keogh, B., Coughlan, R. J., O’Donoghue, J., Foley-Nolan, D., Woods, R., Choudhry, L., Byrne, P., Barry, C., Coughlan, R. J., McCarthy, C. J., Regan, Marian, Coughlan, R. J., Barry, C., McCarthy, J., Coughlin, R. J., Barry, C., McCarthy, C., Foley-Nolan, D., Coughlan, R., Barry, C., Sant, T. J., Healy, S., Casey, E. B., Healy, E., Sant, S., Tyrrell, J., Casey, E. B., Sant, S., Barry, M., Murphy, G., Sant, S., Barry, M., Murphy, G., Veale, D., Rogers, S., Barnes, L., FitzGerald, O., Cooney, J., Veale, D., McQuillan, R., Leahy, A., Barton, J., McMahon, M., Bouchier-Hayes, C., Courtney, G., Doyle, J. S., FitzGerald, O., Taggart, A. J., McEvoy, F., Heylings, D., McMillin, P., Hassan, J., Yarani, G., Feighery, C., Bresnihan, B., Whelan, A., Doherty, Eva, Bresnihan, B., Harden, Catherine, Feighery, C., Jackson, J., Yanni, G., Whelan, A., Feighery, C., Bresnihan, B., Yanni, G., Whelan, A., Feighery, C., FitzGerald, O., Breshihan, B., Shaw, B., and FitzGerald, O.

Published
1991
Full Text
View/download PDF

11. Irish society of gastroenterlogy: Proceedings of Winter Meeting, Belfast City Hospital, Friday 24th and Saturday 25th November, 1989

Author

Watson, R. G. P., Bhatt, B. M., Porter, K. G., Doherty, C., McCaughey, C., Wilson, T. S., Hughes, D. F., Biggart, J. D., Little, C. L., Corbett-Feeney, G. C., Little, M. P. G., McCarthy, C. F., Kavanagh, G., Kee, S., McNulty, J., Fielding, J. F., Huang, J., Smyth, C., Arbuthnott, J. P., Kennedy, N. P., Chua, A., Keeling, P. W. N., Lappin, J., Gillen, P., Burke, P., Hyland, J., Hill, A. D., O’Donoghue, D. P., McGrath, S. J., Buchanan, K. D., Johnston, C. F., Barry, K., Waldron, D. J., Horgan, P. G., McGuire, M., Given, H. F., Bamford, K. B., Collins, J. S. A., Hughes, D. F., Porter, K. G., Wilson., T. S., Patchett, S., O’Riordan, T., Leen, E., Keane, C., O’Morain, C., Gilroy, D. G., Mackle, E. J., Spence, R. A. J., Johnson, G. W., O’Sullivan, K. R., Mathias, P. M., Tobin, A., O’Morain, C. A., Carson, M. E., Stevens, F. M., Bourke, M., Kearns, M., Gannon, F., McCarthy, C. F., Patchett, S., O’Donoghue., D. P., Chua, A., Ah-Kion, S., O’Driscoll, M., Kennedy, N. P., Lee, E., Bolger, C., Kelleher, P., McDonald, M., Byrne, P. J., Gorey, T., Hennessy, T. P., Casey, E. B., MacMahon, M., Hogan, B., O’Sullivan, M., Courtney, M. G., Doyle, J. S., Burke, P., Lappin, J., Hyland, J., Chua, A., Ah-Kion, S., Hamilton, D., Dinan, T., Keeling, P. W. N., Stevens, Fiona M., Nugent, D., Fottrell, P. F., Templeton, J. L., Madden, M., Elliot, M., Chua, A., Kion, A. Ah, Keeling, P. W. N., Yatham, L. N., Barry, S., Dinan, T., Boyle, T., Burke, P., Hyland, J., Kavanagh, G., Veale, D. J., Fitzgerald, O., Fielding, J. F., McDonald, G. S. A., Courtney, M. G., McCann, S. R., Keeling, P. W. N., Weir, D. G., Horgan, P. G., Saleh, H., Waldron, D., Barry, K., McGuire, M., and Given, H. F.

Published
1990
Full Text
View/download PDF

15. Irish Society of Gastroenterology: Proceedings of the winter meeting of the irish society of gastroenterology, held in the royal college of surgeons

Author

McGee, D., Hurley, M. F., Shinkwin, M., Kirwan., W. O., Brady, H. R., O’Donoghue, D. P., Maxwell, R. J., Parks., T. G., Habba, S. F., Doyle, J. S., McCoy, G. F., Parks, T. G., Keane, F., Stephens, R., O’Connor, M., Byrne, P. J., Hennessy, T. P., Gallagher, C., Lennon, J., Crowe, J., O’Connell, D., Browne, Harold J., Legge, D., Kelleher, D., Bloomfield, J., Whelan, A., Weir, D., O’Donoghue, D. P., FitzGerald, O., Conalty, M. L., Courtney, D. F., Clanachan, A. S., Scott, G. W., Shattock, Alan G., McKeever, Una, Feighery, C., Weir, D., Cryan, E. M., Stevens, F. M., Fottrell, P. F., McNicholl, B., McCarthy, F., Arthurs, Yvonne, Doyle, G. D., Fielding, J. F., O’Grady, J. G., Stevens, F. M., Fottrell, P. F., McNicholl, B., O’Gorman, T. A., McCarthy, F., Sheahan, D. G., West, A. B., Stephens, R. B., Hennessy, T. P., McEntee, G., Gorey, T. F., Heffernan, S. J., Duignan, J. P., Duignan, J., Wesler, M., O’Higgins, N., O’Malley, E., MacLean, L. D., Watson, R. G. K., Devery, R., Collins, P. B., and Johnson, A. H.

Published
1982
Full Text
View/download PDF

17. Irish Society of Gastroenterology: Proceedings of the Irish Society of Gastroenterology, 24th/25th May, 1985

Author

Whelton, M. J., Fitzgerald, P., Ritchie, E., Jenkins, D., Leahy, A. L., Nee, J. M., Wait, R. B., Pollock, T. W., Collins, B. J., Elliott, H., Sloan, J. M., McFarland, R. J., Love, A. H. G., Mac Mathúna, P., O’Reilly, T., Kelleher, D., Keeling, P. W. N., Feely, J., West, B., Byrne, P., Sheahan, G., Stephens, R., Hennessy, T., Doyle, C. T., Bloomfield, F. J., Maxwell, W. J., Hogan, F. P., Walsh, J. P., Duffy, M. J., O’Sullivan, F., O’Donoghue, D., Afdhal, N., Collins, J. S. A., Kennedy, T. L., Buchanan, K. D., Johnston, C. F., O’Hare, M. M. T., Walsh, T. N., Alderson, D., Tate, P., Lavells, M. I., Ryan, P., Lennon, G., Walsh, D., Hegarty, J. H., Keane, F. B. V., Tanner, W. A., Afdhal, N. H., Long, A. A., Tobbia, I., Tobin, B., O’Rafferty, R., O’Donoghue, D. P., Deasy, J., Clinton, O., Burke, G., Delaney, P., O’Mahony, C., O’Farrelly, C., Weir, D. G., Finch, T., Feighery, C. F., Traynor, O. J., Byrne, P. J., Hennessy, T. P. J., Lombard, M., Murray, F. E., Connolly, G., Lennon, J., Crowe, J., McCann, A., Seymour, C., Broe, P. J., Bouchier-Hayes, D. J., Bloomfield, F. F., O’Farrelly, Cliona, Stevens, F., McCarthy, C., Feighery, C., McKee, C. M., McMillan, S. A., Dawson, A. T., O’Toole, J., Haire, Margaret, Callender, M. E., Fulton, T. T., McEntee, G. P., Duignan, J. P., O’Malley, E., Graeme-Cook, F., O’Farrelly, G., O’B Hourihane, D., Fitzgerald, R., Dervan, P., Lennon, J. R., Moran, B., Delaney, P. V., Kelly, J., O’Shea, B., O’Dorioghue, D. P., Keeling, P., Stuart, R., Stewart, R. J., Parks, T. G., Devery, R., Tomkin, G. H., McKay, P. A., O’Connor, M., Miller, S., McDonald, G., Fryene, P. J., Martin, L., Ryan, F., Collum, C., Lavelle, J., Ennis, J., Doyle, J. S., O’Connor, H. J., Schorah, C. J., Axon, A. T. R., Riley, S. E., Garner, R. C., Burke, O., Long, J. P., and Lennon, F.

Published
1986
Full Text
View/download PDF

18. Royal academy of medicine in Ireland Section of biological sciences: Proceedings of meeting held at the Veterinary College of Ireland, Dublin, 30th December, 1981

Author

Kisauzi, D. N., Leek, B. F., Lucas, K. St. J., Grovum, W. L., Barry, David, Hartigan, Patrick J., Bannigan, J., Vybiral, S., Andrews, J. F., Brennan, M., Loughran, J., McKee, Gabrielle, Donne, B., Smith, J., Murphy, J., Doyle, J. S., Darragh, A., O’Boyle, C., Lambe, R., Brick, I., Hardiman, Orla, Buckley, J., Hall, W. J., Blunnie, W. P., Moore, J., Merrett, J. D., Dundee, J. W., Mcllroy, P. D. A., McAuley, D. M., McCaughey, W., Beers, H. T. B., McArdle, L., Black, G. W., Callanan, K., Keenan, A. K., Levitzki, A., O’Connor, P. C., Slater, P., Murray, J. A., Comerford, F. R., Hooper, A. C. B., Cotter, T. G., Henson, P. M., Silke, B., Nelson, G. I., Kumar, E., Ahuja, R., Taylor, S. H., Hendry, W. G., O’Donnell, J. M., Kovacs, T., Maurer, B. J., Doyle, V. M., O’Malley, K., Kelly, J. G., Kawar, P., Briggs, L. P., Bullock, Caroline G., Gilmore, Ruth St., and Wallace, William F. M.

Published
1982
Full Text
View/download PDF

22. Book reviews

Author

Stickler, D. J., Dockeray, Sylvia, Kernohan, R. J., Lyons, J. B., Doyle, J. S., Walsh, A., Gallagher, J. G., Bofin, P. J., and Wilson, D. J.

Published
1972
Full Text
View/download PDF

23. Book reviews

Author

Buckley, D. B., Towers, Robert P., Mooney, D., Harrington, M. R., O’Doherty, N., Doyle, J. S., and Powell, David

Published
1976
Full Text
View/download PDF

24. Book reviews

Author

Mooney, D., McQuaid, Paul E., Foley, B. V., Kennedy, A. L., and Doyle, J. S.

Published
1976
Full Text
View/download PDF

25. Book reviews

Author

Cannon, Paul J., Cantwell, D. F., Browne, H., O’Rourke, F. J., Murphy, T., Micks, R. H., O’Brien, B., Doyle, J. S., and Meenan, F. O. C.

Published
1960
Full Text
View/download PDF

34. Transmucosal potential difference; diagnostic value in gastro-oseophageal reflux.

Author

Khamis, B, Kennedy, C, Finucane, J, and Doyle, J S

Abstract

Nineteen patients with symptoms of upper gastrointestinal disease were assessed by endoscopy. Transmucosal potential difference (PD) in the lower oesophagus was recorded and suction biopsy specimens were obtained from the site of measurement and examined by light microscopy after haematoxylin and eosin staining. In 10 patients with normal histology, mean PD was--14.4 mV (SEM +/- 0.4 mV), whereas in nine patients with histological changes of reflux mean was +9.4 mV (SEM +/- 3.0 mV). In this latter group, polarity of the PD was reversed in all but one case. Good correlation was found between these objective indices of lower oesophageal disease and the presence of symptoms such as dysphagia and heartburn. The visual appearance at endoscopy was less reliable. It is suggested that measurement of PD is a simple, rapid, and sensitive method of detecting the presence of oesophageal mucosal damage. [ABSTRACT FROM PUBLISHER]

Published
1978

35. Zoological Society of London: Contributions towards advancing the field of herpetology through conservation, research, captive management and education

Author

Benjamin Tapley, Bielby, J., Böhm, M., Brookes, L., Capel, T., Capon-Doyle, J. S., Chen, S., Cliffe, A., Clifforde, L., Couchman, O., Cunningham, A. A., Feltrer, Y., Ferguson, A., Flach, E., Franklin, M., Garner, T. W. J., Gill, I., Gray, C. L., Gumbs, R., Guthrie, A., Jaffe, J., Jayson, S., Harding, L., Hudson, M., Kane, D., Korn, J., Lawson, B., Macintosh, H., Masters, N., Maunders, T., Molenaar, F., Michaels, C. J., Moxey, T., Murray, C., Owen, N., Pearce-Kelly, P., Rendle, M., Sainsbury, T., Sergeant, C., Servini, F., Sparrow, S., Strike, T., Thomas, S., and Turvey, S.

37. Constructing a 'target population': A critical analysis of public health discourse on substance use among gay and bisexual men, 2000-2020.

Author

Schroeder, SE, Bourne, A, Doyle, JS, Hellard, ME, Stoové, M, Pedrana, A, Schroeder, S E, Doyle, J S, and Hellard, M E

Subjects
*BISEXUALITY, *SUBSTANCE abuse, *HUMAN sexuality, *PUBLIC health, *HOMOSEXUALITY
Abstract

Background: Gay and bisexual men (GBM) have higher substance use prevalences than general population samples - often attributed to stigmatisation of sexual minority identities. We examined how influential public health research on substance use among GBM interprets this behaviour and what GBM-specific identities emerge through the discourses employed.Methods: We searched Web of Science for publications on substance use among GBM, selecting 60 of the most cited papers published during 2000-2020. We studied the language used to describe and interpret drug-using behaviour using critical discourse analysis, focusing on interpretive repertoires and subject positions.Results: Three distinct discursive tendencies were identified. First, in constructing a target population, GBM who use illicit drugs are positioned as deficient, socially irresponsible, and maladapted to dealing with stigmatisation and HIV risks. Second, in shifting the focus beyond the individual, the gay community is conceptualised as offering a safe space for socialisation. Nonetheless, gay community spaces are problematised as promoting substance use among vulnerable GBM through aggravating loneliness and normalising drug use as a form of maladaptive (avoidance) coping. Third, counterdiscursive movements add nuance, context, and comparisons that relativise rather than generalise substance use and focus on pleasure and self-determination. Such discourses centre the need for interventions that disrupt homophobic socio-structures instead of individualising approaches to limit non-conformity.Conclusion: 'Expert' assessments of substance use among GBM perpetuate pathologising understandings of this behaviour and promote abject subject positions, contributing to perpetuations of intergroup stigma and social exclusion based on drug and sexual practices. Our findings highlight the need for deliberate and critical engagement with prior research and a conscious effort to disrupt dominant discourses on GBM's substance use. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

38. Financial incentives to increase engagement across the hepatitis C care cascade among people at risk of or diagnosed with hepatitis C: A systematic review.

Author

Shen C, Dawe J, Traeger MW, Sacks-Davis R, Pedrana AE, Doyle JS, Hellard ME, and Stoové M

Subjects
Humans, Antiviral Agents therapeutic use, Antiviral Agents economics, Motivation, Hepatitis C
Abstract

Background: Reversing declining rates of people initiating and completing hepatitis C (HCV) treatment, observed in many countries, is needed to achieve global HCV elimination goals. Providing financial incentives to increase HCV testing and treatment uptake among people at-risk of or living with HCV infection could be an effective intervention. We conducted a systematic review to assess evidence regarding the effectiveness of financial incentives to improve engagement and progression through the HCV care cascade., Methods: We searched MEDLINE, PubMed and EMBASE for studies published from January 2013 to January 2023 that evaluated financial incentives offered to people living with and at-risk of HCV to increase HCV antibody and or RNA testing, linkage to care, treatment initiation, treatment adherence, treatment completion, and sustained viral load (SVR) testing. Open-label randomised controlled trials (RCTs), controlled non-randomised studies, cohort or observation studies and mixed-methods studies were included, whereas literature reviews, case series and studies which did not report data were excluded., Results: We identified 1,278 studies, with 21 included after full-text screening (14,913 participants); three randomised controlled trials and 18 non-randomised studies. Studies evaluated incentives aimed at improving test uptake (n = 11), engagement in care (n = 13), treatment initiation (n = 8), adherence (n = 3), completion (n = 3) and attainment of SVR (n = 5). Findings provided inconclusive evidence for the effectiveness of incentives in improving engagement in the HCV cascade of care. Determining incentive effectiveness to improve care cascade engagement was limited by low quality study designs, heterogeneity in type (cash or voucher), value (US$5 to $600) and cascade stage being incentivised. No randomised controlled trials assessed the effectiveness of incentives to promote HCV testing, and none showed an impact on treatment uptake. In non-randomised studies (observational comparative), some evidence suggested that incentives promoted HCV testing, but evidence of their role in promoting linkage to care, HCV treatment adherence and treatment completion were mixed., Conclusion: Currently, there lacks high-quality evidence evaluating whether financial incentives improve HCV testing and treatment outcomes. Future research should seek to standardise methodologies, compare incentive types and values to enhance engagement in HCV care, and determine factors that support incentives effectiveness., Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: MWT has received investigator-initiated research funding, speakers honoraria and consultant fees from Gilead Sciences for activities unrelated to this work. AP has received investigator-initiated research funding from Gilead Sciences and AbbVie and consultant fees from Gilead Sciences for activities unrelated to this work. JSD and MEH receives funding from Gilead Sciences and Abbvie for investigator-initiated research, unrelated to the submitted work. MS has received investigator-initiated research funding from Gilead Sciences and AbbVie and consultant fees from Gilead Sciences for activities unrelated to this work. Burnet Institute receives funding support (outside this study) from the Victorian Government Operational Infrastructure Fund., (Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)

Published
2024
Full Text
View/download PDF

39. Prevalence of baseline HCV NS5A resistance associated substitutions in genotype 1a, 1b and 3 infection in Australia.

Author

Papaluca T, O'Keefe J, Bowden S, Doyle JS, Stoove M, Hellard M, and Thompson AJ

Subjects
Amino Acid Substitution, Australia epidemiology, Female, Genotype, Hepatitis C, Chronic virology, Humans, Male, Prevalence, RNA, Viral genetics, Sequence Analysis, RNA, Drug Resistance, Viral, Hepacivirus genetics, Hepatitis C, Chronic drug therapy, Viral Nonstructural Proteins genetics
Abstract

Background: Direct-acting antivirals (DAA) have revolutionised hepatitis C virus (HCV) treatment, and most regimens include an NS5A inhibitor. Certain amino-acid substitutions confer resistance to NS5A inhibitors, termed resistance-associated substitutions (RAS). If present at baseline, they can reduce virological response rates. Population-based sequencing (PBS) is generally used for baseline sequencing, however next generation sequencing (NGS) reduces the threshold for detection of sequences encoding RAS from 20% to 5%. We determined the prevalence of NS5A RAS at baseline amongst Australian chronically infected with genotype (GT)1a, GT1b and GT3 HCV, using both PBS and NGS., Methods: Samples from DAA-naïve individuals were received at the Victorian Infectious Disease Reference Laboratory between June 2016 and December 2018. All samples were analysed for NS5A RAS using PBS. A subset of GT1 HCV samples were processed using NGS technology (Vela Diagnostics, Singapore) to determine the improvement in sensitivity., Results: In total, 672 samples were analysed using PBS. The baseline prevalence of NS5A RAS was 7.6% for GT1a (n = 25/329), 15.7% for GT1b (n = 8/51) and 15.1% for GT3 (n = 44/292). NGS only marginally increased sensitivity for NS5A RAS at baseline in GT1a (16% vs 17%) and GT1b (29% vs 36%)., Conclusion: The prevalence of NS5A RAS in GT1a HCV in Australia was low compared with international data, and was similar to other reported international prevalence for GT1b and GT3 infection. NGS at baseline only marginally increased sensitivity for the detection of NS5A RAS in patients with GT1 HCV and cannot be recommended for routine use at baseline in clinical practice., (Copyright © 2019 Elsevier B.V. All rights reserved.)

Published
2019
Full Text
View/download PDF

40. The contemporary surgical management of spasticity in children.

Author

Grabb PA and Doyle JS

Subjects
Child, Humans, Orthopedic Procedures, Treatment Outcome, Baclofen therapeutic use, GABA Agonists therapeutic use, Muscle Spasticity surgery, Rhizotomy methods
Abstract

Orthopedics and neurosurgery offer multiple surgical modalities for improving the function, care, and well-being of children with spasticity. One surgical approach is not the best for all children with spasticity not adequately controlled with more conservative measures. For that reason, a multidisciplinary evaluation is important to optimize outcome for these children.

Published
2001

41. Antibiotic therapy attenuates colitis in interleukin 10 gene-deficient mice.

Author

Madsen KL, Doyle JS, Tavernini MM, Jewell LD, Rennie RP, and Fedorak RN

Subjects
Age Factors, Animals, Bacteroides drug effects, Bacteroides growth & development, Clostridium drug effects, Clostridium growth & development, Colitis genetics, Colitis pathology, Enterobacteriaceae drug effects, Enterobacteriaceae Infections genetics, Enterobacteriaceae Infections pathology, Enterococcus drug effects, Enterococcus growth & development, Intestinal Mucosa microbiology, Intestinal Mucosa pathology, Lactobacillus drug effects, Lactobacillus growth & development, Longitudinal Studies, Metronidazole pharmacology, Mice, Mice, Inbred Strains, Mice, Knockout, Neomycin pharmacology, Streptococcus drug effects, Streptococcus growth & development, Anti-Bacterial Agents pharmacology, Ciprofloxacin pharmacology, Colitis drug therapy, Enterobacteriaceae growth & development, Enterobacteriaceae Infections drug therapy, Interleukin-10 genetics
Abstract

Background & Aims: Interleukin (IL)-10 gene-deficient mice, raised under germfree conditions, do not develop colitis, implying a role for bacteria. This study mapped the appearance of luminal colonic bacteria and, using antibiotic treatment, determined their association with colitis in IL-10 gene-deficient mice., Methods: Mice were treated with ciprofloxacin or with neomycin and metronidazole. The intestine was harvested for histological scoring and bacterial assessment., Results: At 2 weeks of age, before the development of colitis, IL-10 gene-deficient mice demonstrated an earlier appearance of Streptococcus and Clostridium sp., and had a greater proportion (P < 0.01) of bacteria adherent to the colonic mucosa. This pattern of increased adherent bacteria persisted for the 12 weeks of study. Treatment of mice before the onset of colonic inflammation, with either antibiotic regime, reduced mucosal adherent bacteria and prevented colitis (P < 0.01). In contrast, treatment of established colitis with neomycin and metronidazole did not reduce adherent bacterial levels, yet was more efficacious (P < 0.05) in treating established colitis than ciprofloxacin, which did reduce adherent colonic bacteria., Conclusions: In the IL-10 gene-deficient mouse model, the appearance and number of mucosal adherent colonic bacteria are altered before the onset of colitis. Antibiotics both prevent and treat the colitis through correction of this primary bacterial alteration.

Published
2000
Full Text
View/download PDF

42. Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora.

Author

Madsen KL, Malfair D, Gray D, Doyle JS, Jewell LD, and Fedorak RN

Subjects
Animals, Colon microbiology, Colon pathology, Culture Techniques, Germ-Free Life, Ileum microbiology, Ileum pathology, Inflammatory Bowel Diseases pathology, Interleukin-10 deficiency, Intestinal Mucosa pathology, Mice, Mice, Inbred Strains, Permeability, Reference Values, Sensitivity and Specificity, Colon metabolism, Cytokines metabolism, Ileum metabolism, Inflammatory Bowel Diseases genetics, Interleukin-10 genetics, Intestinal Mucosa metabolism, Intestinal Mucosa microbiology
Abstract

The normal intestinal epithelium provides a barrier relatively impermeable to luminal constituents. However, patients with inflammatory bowel disease experience enhanced intestinal permeability that correlates with the degree of injury. IL-10 gene-deficient mice were studied to determine whether increased intestinal permeability occurs as a primary defect before the onset of mucosal inflammation or is secondary to mucosal injury. At 2 weeks of age, IL-10 gene-deficient mice show an increase in ileal and colonic permeability in the absence of any histological injury. This primary permeability defect is associated with increased mucosal secretion of interferon-gamma and tumor necrosis factor-alpha, and does not involve an increase in nitric oxide synthase activity. Colonic permeability remains elevated as inflammation progresses, while ileal permeability normalizes by 6 weeks of age. IL-10 gene-deficient mice raised under germ-free conditions have no inflammation, and demonstrate normal permeability and cytokine levels. This data suggests that the intestinal permeability defect in IL-10 gene-deficient mice occurs due to a dysregulated immune response to normal enteric microflora and, furthermore, this permeability defect exists prior to the development of mucosal inflammation.

Published
1999
Full Text
View/download PDF

43. Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice.

Author

Madsen KL, Doyle JS, Jewell LD, Tavernini MM, and Fedorak RN

Subjects
Age Factors, Animals, Animals, Newborn, Bacteria, Aerobic isolation & purification, Colitis genetics, Colitis pathology, Colitis therapy, Colon microbiology, Colon pathology, Gastrointestinal Contents drug effects, Gastrointestinal Contents microbiology, Ileum microbiology, Ileum pathology, Interleukin-10 genetics, Lactobacillus isolation & purification, Lactulose therapeutic use, Mice, Mice, Knockout, Probiotics therapeutic use, Specific Pathogen-Free Organisms, Colitis microbiology, Interleukin-10 deficiency, Lactobacillus physiology
Abstract

Background & Aims: Intestinal luminal microflora, or their products, are likely an important initiating factor in the pathogenesis of inflammatory bowel disease. The aim of this study was to determine the role of colonic aerobic luminal bacteria and Lactobacillus species in the development of colitis in interleukin (IL)-10 gene-deficient mice., Methods: Intestine from 2-16-week-old mice was scored histologically and cultured for bacteria. Lactobacillus sp. repopulation of the colonic lumen was achieved via daily rectal delivery of Lactobacillus reuteri or oral lactulose therapy., Results: At 2 weeks of age, IL-10 gene-deficient mice showed no colonic injury but did display abnormal colonic bacterial colonization with increased colonic mucosal aerobic adherent and translocated bacteria in conjunction with reduced Lactobacillus sp. levels. In association with the abnormal colonic bacterial colonization, colitis developed by 4 weeks of age. Restoring Lactobacillus sp. to normal levels reduced levels of colonic mucosal adherent and translocated bacteria and attenuated the development of the colitis., Conclusions: In the neonatal period, IL-10 gene-deficient mice have decreased levels of colonic Lactobacillus sp. and an increase in colonic mucosal adherent and translocated bacteria. Normalizing Lactobacillus sp. levels reduced colonic mucosal adherent and translocated bacteria and prevented colitis.

Published
1999
Full Text
View/download PDF

44. Polymorphonuclear leukocyte-mediated bone degradation and influence of blood mononuclear cells on the mouse calvarial model.

Author

Wang YH, Allardyce RA, Rogers GR, Gillespie WJ, and Doyle JS

Subjects
Animals, Coculture Techniques, Culture Media, Conditioned, Culture Techniques, Humans, Leukocytes, Mononuclear physiology, Mice, Skull pathology, Bone Resorption etiology, Neutrophils physiology, Osteomyelitis pathology, Staphylococcal Infections pathology
Abstract

Objective: To investigate the relationships between degradation of bone and activated blood polymorphonuclear leukocytes (PMNL) and mononuclear leukocytes (ML) as well as their soluble products in vitro., Materials and Methods: A neonatal mouse calvarial bone model was used to assess the activity of degradation (by measuring the amount of 45Ca release) by normal human blood leukocytes, separated PMNL and ML following 24-hour incubation. The effects of conditioned culture medium obtained from Staphylococcus aureus-stimulated ML on PMNL-mediated calvarial bone loss were also studied., Results: It was demonstrated that isolated human PMNL rapidly degraded bone in a dose and time dependent manner. The PMNL-mediated bone degradation was enhanced by conditioned medium obtained from Staphylococcus aureus-stimulated ML., Conclusion: These findings implicate PMNL as major contributors to early bone loss in infectious diseases such as acute haematogenous osteomyelitis.

Published
1996

45. The destruction of bone by neutrophils.

Author

Allardyce RA, Wang Y, Rogers GR, Gillespia WJ, and Doyle JS

Subjects
Animals, Animals, Newborn, Fetus, Mice, Osteomyelitis complications, Bone Resorption etiology, Neutrophils physiology, Osteomyelitis pathology, Tibia pathology
Published
1995

46. Granulomatous gastritis: part of a vasculitic syndrome.

Author

O'Donovan C, Murray J, Staunton H, Doyle JS, and Leader M

Subjects
Female, Humans, Middle Aged, Syndrome, Gastritis pathology, Granuloma pathology, Vasculitis pathology
Abstract

The previously unreported association of granulomatous gastritis and mononeuritis multiplex occurring in the setting of a vasculitic syndrome is described. The two conditions are considered to be associated and to be immune mediated. The previously accepted concept of isolated granulomatous gastritis is disputed.

Published
1991
Full Text
View/download PDF

47. Audit of cranial computerised tomography in a general medical unit.

Author

Curley P, Lynch T, Walker F, and Doyle JS

Subjects
Adult, Female, Humans, Ireland, Male, Medical Audit, Middle Aged, Tomography, X-Ray Computed statistics & numerical data, Brain Diseases diagnostic imaging, Tomography, X-Ray Computed standards
Abstract

Over a two year period 108 patients had cranial computerised tomographic (CCT) scans while under the care of a general medical team. Sixty eight scans showed 70 abnormalities. Completed stroke, transient ischaemic attacks (TIA), epilepsy and headache were the most common indications for CTT while infarct, atrophy, haemorrhage and tumour were the most common abnormalities. Eight tumours were identified comprising 12% of epileptics and 9% of stroke patients.

Published
1990
Full Text
View/download PDF

48. Large bowel cancer: an Irish epidemic?

Author

Habba SF and Doyle JS

Subjects
Adult, Aged, Humans, Ireland, Middle Aged, Colonic Neoplasms prevention & control, Rectal Neoplasms prevention & control
Published
1982

50. Vasoactive intestinal peptide: behavioral effects in the rat and hamster.

Author

Kulkosky PJ, Doyle JS, Cook VI, Glazner GW, and Foderaro MA

Subjects
Alcohol Drinking, Animals, Cholecystokinin pharmacology, Cricetinae, Ethanol pharmacology, Female, Male, Rats, Behavior, Animal drug effects, Vasoactive Intestinal Peptide pharmacology
Abstract

The behavioral effects of intracerebroventricular (ICV) injection of the brain-gut peptide vasoactive intestinal peptide (VIP) were quantified with a behavioral sampling technique in home-caged, nondeprived, male and female albino rats and golden hamsters. ICV VIP sex-dependently decreased observed resting behavior during 1 hr after injections in both rats and hamsters at 0.1-10.0 micrograms. Grooming behavior was increased in hamsters, and rearing and standing behaviors were increased in rats, sex-dependently at VIP doses that decreased resting. Drinking behavior was suppressed in rats by VIP at 10.0 micrograms. Intraperitoneal (IP) VIP (100.0 micrograms/kg) increased 5% ethanol intake and decreased eating behavior in fluid-deprived male rats. The increase in ethanol intake produced by IP VIP was prevented by IP cholecystokinin octapeptide (CCK, 4.0 micrograms/kg). VIP potently controls resting and ingestive behaviors, suggesting a role for this neuropeptide, along with CCK, in the feedback regulation of rodent behavior.

Published
1989
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results