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1. Efficacy of endoscopic submucosal resection with a ligation device for small rectal neuroendocrine tumor: study protocol of a multicenter open-label randomized control trial (BANDIT trial)

Author

Takada, Kazunori, Imai, Kenichiro, Yamada, Takanori, Ohata, Ken, Kanesaka, Takashi, Nagami, Yasuaki, Yamasaki, Yasushi, Kobara, Hideki, Inokuchi, Yasuhiro, Chino, Akiko, Yamaguchi, Shinjiro, Ikehara, Hisatomo, Kawamura, Takuji, Yabuuchi, Yohei, Mizuguchi, Yasuhiko, Ikematsu, Hiroaki, Yokoi, Chizu, Hattori, Santa, Ohno, Kazuya, Yoshizawa, Yashiro, Fukuzawa, Masakatsu, Tsuji, Yosuke, Konishi, Jun, Yamamura, Takeshi, Osawa, Satoshi, Oka, Shiro, Hikichi, Takuto, Togashi, Kazutomo, Hirasawa, Kingo, Uraoka, Toshio, Takeuchi, Yoji, Chiba, Hideyuki, Komeda, Yoriaki, Doyama, Hisashi, Oba, Mari S., and Saito, Yutaka

Published
2024
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3. Adenoma (Papillary Region)

Author

Tsuji, Shigetsugu, Doyama, Hisashi, Sano, Yasushi, editor, Chiu, Philip, editor, Singh, Rajvinder, editor, Uedo, Noriya, editor, Goda, Kenichi, editor, and Katada, Chikatoshi, editor

Published
2024
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4. Metachronous primary gastric cancer after endoscopic resection in patients with esophageal squamous cell carcinoma

Author

Hirao, Motohiro, Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Suzuki, Haruhisa, Furue, Yasuaki, Yamamoto, Keiko, Doyama, Hisashi, Koike, Tomoyuki, Tamaoki, Masashi, Kawata, Noboru, Kawahara, Yoshiro, Katagiri, Atsushi, Ogata, Takashi, Yamanouchi, Takenori, Kiyokawa, Hirofumi, Kawakubo, Hirofumi, Konno, Maki, Ishikawa, Hideki, Yokoyama, Akira, and Muto, Manabu

Published
2023
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7. Final Analysis of Diagnostic Endoscopic Resection Followed by Selective Chemoradiotherapy for Stage I Esophageal Cancer: JCOG0508

Author

Mizuaswa, Junki, Takizawa, Kohei, Aoyama, Ikuo, Ishiyama, Akiyoshi, Kawata, Noboru, Kikuchi, Daisuke, Hanaoka, Noboru, Oda, Ichiro, Morita, Yoshinori, Tajika, Masahiro, Fujiwara, Junko, Yamamoto, Yoshinobu, Katada, Chikatoshi, Hori, Shinichiro, Doyama, Hisashi, Oyama, Tsuneo, Nebiki, Hiroko, Amagai, Kenji, Kubota, Yutaro, Inokuchi, Yasuhiro, Kobayashi, Nozomu, Suzuki, Takuto, Hirasawa, Kingo, Takeuchi, Toshihisa, Kadota, Tomohiro, Nihei, Keiji, Minashi, Keiko, Yano, Tomonori, Shimoda, Tadakazu, Fukuda, Haruhiko, and Muto, Manabu

Published
2023
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8. Influence of hospital volume on bleeding after endoscopic submucosal dissection for early gastric cancer in Japan: a multicenter propensity score-matched analysis

Author

Yabuuchi, Yohei, Hatta, Waku, Tsuji, Yosuke, Yoshio, Toshiyuki, Kakushima, Naomi, Hoteya, Shu, Doyama, Hisashi, Nagami, Yasuaki, Hikichi, Takuto, Kobayashi, Masakuni, Morita, Yoshinori, Sumiyoshi, Tetsuya, Iguchi, Mikitaka, Tomida, Hideomi, Inoue, Takuya, Mikami, Tatsuya, Hasatani, Kenkei, Nishikawa, Jun, Matsumura, Tomoaki, Nebiki, Hiroko, Nakamatsu, Dai, Ohnita, Ken, Suzuki, Haruhisa, Ueyama, Hiroya, Hayashi, Yoshito, Sugimoto, Mitsushige, Yamaguchi, Shinjiro, Michida, Tomoki, Yada, Tomoyuki, Asahina, Yoshiro, Narasaka, Toshiaki, Kuribayashi, Shiko, Kiyotoki, Shu, Mabe, Katsuhiro, Fujishiro, Mitsuhiro, Masamune, Atsushi, and Ono, Hiroyuki

Published
2022
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9. Radiation Exposure with Self-Expandable Metallic Stent versus Transanal Decompression Tube for Malignant Colorectal Obstruction: A Post Hoc Propensity Score Matched Analysis.

Author

Tamaru, Yuzuru, Kuwai, Toshio, Hayashi, Shiro, Nagaike, Koji, Yakushijin, Takayuki, Asai, Satoshi, Yamamoto, Masashi, Yamaguchi, Shinjiro, Yamada, Takuya, Hasatani, Kenkei, Ihara, Hideyuki, Tsumura, Hidetaka, Doyama, Hisashi, Maetani, Iruru, Fujisawa, Toshio, Ito, Yukiko, Takagi, Tadayuki, Hori, Yasuki, Takenaka, Mamoru, and Hosono, Makoto

Subjects
PROPENSITY score matching, RADIATION exposure, LOCATION analysis, RECTUM, LONGITUDINAL method
Abstract

Background: Although several reports have compared the outcomes of self-expandable metallic stent (SEMSs) and transanal decompression tube (TDT) placement for malignant colorectal obstruction (MCO), few studies have compared the radiation exposure (RE) associated with these two procedures. Consequently, we aimed to compare the RE of SEMS and TDT placements for MCO using propensity score matching (PSM) in a multi-center, prospective observational study. Methods: This study investigated the clinical data of 236 patients who underwent SEMS or TDT placement. The air kerma at the patient entrance reference point (Ka,r: mGy) and air kerma–area product (PKA; Gycm2) were measured and compared between SEMS and TDT groups after PSM. Results: After PSM, 61 patients were identified in each group. The median Ka,r in the SEMS group was significantly greater than that in the TDT group (77.4 vs. 55.6 mGy; p = 0.025) across the entire cohort. With respect to subgroup analyses by location, in the rectum, the median Ka, r and PKA were significantly greater in the SEMS group than in the TDT group (172.9 vs. 34.6 mGy; p = 0.001; and 46.0 vs. 18.1 Gycm2; p = 0.006, respectively). However, in the colon, the RE parameters did not significantly differ between the two groups. Conclusions: TDT might be a more suitable option for decompression in patients with malignant rectal obstruction due to its lower RE and technical advantages. Conversely, SEMS placement is recommended as the first decompression method to treat malignant colonic obstruction, in line with the current guidelines. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Field Effect of Alcohol, Cigarette Smoking, and Their Cessation on the Development of Multiple Dysplastic Lesions and Squamous Cell Carcinoma: A Long-term Multicenter Cohort Study

Author

Kaneko, Kazuhiro, Morita, Shuko, Funakoshi, Makiko, Horimatsu, Takahiro, Takahashi, Mari, Suzuki, Haruhisa, Abiko, Satoshi, Takemura, Kenichi, Nakanishi, Hiroyoshi, Saito, Masahiro, Ara, Nobuyuki, Kakushima, Naomi, Tanaka, Masaki, Hori, Keisuke, Tsuda, Takashi, Muto, Manabu, Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Oda, Ichiro, Ezoe, Yasumasa, Tanabe, Satoshi, Shimizu, Yuichi, Doyama, Hisashi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Okada, Hiroyuki, Ogata, Takashi, Katagiri, Atsushi, Yamanouchi, Takenori, Matsuo, Yasumasa, Kawakubo, Hirofumi, Omori, Tai, Kobayashi, Nozomu, Shimoda, Tadakazu, Ochiai, Atsushi, Ishikawa, Hideki, Baba, Kiichiro, Amanuna, Yusuke, Yokoyama, Akira, and Ohashi, Shinya

Published
2022
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11. Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial

Author

Ishikawa, Hideki, Mutoh, Michihiro, Sato, Yasushi, Doyama, Hisashi, Tajika, Masahiro, Tanaka, Shinji, Horimatsu, Takahiro, Takeuchi, Yoji, Kashida, Hiroshi, Tashiro, Jun, Ezoe, Yasumasa, Nakajima, Takeshi, Ikematsu, Hiroaki, Hori, Shinichiro, Suzuki, Sadao, Otani, Takahiro, Takayama, Tetsuji, Ohda, Yoshio, Mure, Kanae, Wakabayashi, Keiji, and Sakai, Toshiyuki

Published
2021
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14. Outcomes of noncurative endoscopic submucosal dissection for T1 colorectal cancer: Prospective, multicenter, cohort study in Japan.

Author

Tsuji, Shigetsugu, Doyama, Hisashi, Kobayashi, Nozomu, Ohata, Ken, Takeuchi, Yoji, Chino, Akiko, Takamaru, Hiroyuki, Tsuji, Yosuke, Hotta, Kinichi, Harada, Keita, Ikematsu, Hiroaki, Uraoka, Toshio, Murakami, Takashi, Katagiri, Atsushi, Hori, Shinichiro, Michida, Tomoki, Suzuki, Takuto, Fukuzawa, Masakatsu, Kiriyama, Shinsuke, and Fukase, Kazutoshi

Subjects
*LYMPHATIC metastasis, *RECTAL cancer, *COLON cancer, *COLORECTAL cancer, *CANCER relapse
Abstract

Objectives Methods Results Conclusion This study investigated the incidence of lymph node metastasis and long‐term outcomes in patients with T1 colorectal cancer where endoscopic submucosal dissection (ESD) resulted in noncurative treatment. It is focused on those with deep submucosal invasion, a factor considered a weak predictor of lymph node metastasis in the absence of other risk factors.This nationwide, multicenter, prospective study conducted a post‐hoc analysis of 141 patients with T1 colorectal cancer ≥20 mm where ESD of the lesion resulted in noncurative outcomes, characterized by poor differentiation, deep submucosal invasion (≥1000 μm), lymphovascular invasion, high‐grade tumor budding, or positive vertical margins. Clinicopathologic features and patient prognoses focusing on lesion sites and additional surgery requirements were evaluated. Lymph node metastasis incidence in the low‐risk T1 group, identified by deep submucosal invasion as the sole high‐risk histological feature, was assessed.Lymph node metastasis occurred in 14% of patients undergoing additional surgery post‐noncurative endoscopic submucosal dissection for T1 colorectal cancer. In the low‐risk T1 group, in the absence of other risk factors, the frequency was 9.7%. The lymph node metastasis rates in patients with T1 colon and rectal cancers did not differ significantly (14% vs. 16%). Distant recurrence was observed in one patient (2.3%) in the ESD only group and in one (1.0%) in the additional surgery group, both of whom had had rectal cancer removed.The risk of lymph node metastasis or distant occurrence was not negligible, even in the low‐risk T1 group. The findings suggest the need for considering additional surgery, particularly for rectal lesions (Clinical Trial Registration: UMIN000010136). [ABSTRACT FROM AUTHOR]

Published
2024
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18. Association between macrocytosis and metachronous squamous cell carcinoma of the esophagus after endoscopic resection in men with early esophageal squamous cell carcinoma

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Oda, Ichiro, Shimizu, Yuichi, Doyama, Hisashi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Okada, Hiroyuki, Yoshii, Takako, Kubota, Yutaro, Yamanouchi, Takenori, Tsuda, Takashi, Omori, Tai, Kobayashi, Nozomu, Suzuki, Haruhisa, Tanabe, Satoshi, Hori, Keisuke, Nakayama, Norisuke, Kawakubo, Hirofumi, Kakushima, Naomi, Matsuo, Yasumasa, Ishikawa, Hideki, Yokoyama, Akira, and Muto, Manabu

Published
2020
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19. Factors associated with technical difficulty of endoscopic submucosal dissection for early gastric cancer that met the expanded indication criteria: post hoc analysis of a multi-institutional prospective confirmatory trial (JCOG0607)

Author

Yano, Tomonori, Hasuike, Noriaki, Ono, Hiroyuki, Boku, Narikazu, Ogawa, Gakuto, Kadota, Tomohiro, Oda, Ichiro, Doyama, Hisashi, Hori, Shinichiro, Iishi, Hiroyasu, Takahashi, Akiko, Takizawa, Kohei, and Muto, Manabu

Published
2020
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21. Efficacy of Endoscopic Resection and Selective Chemoradiotherapy for Stage I Esophageal Squamous Cell Carcinoma

Author

Minashi, Keiko, Nihei, Keiji, Mizusawa, Junki, Takizawa, Kohei, Yano, Tomonori, Ezoe, Yasumasa, Tsuchida, Tomohiro, Ono, Hiroyuki, Iizuka, Toshiro, Hanaoka, Noboru, Oda, Ichiro, Morita, Yoshinori, Tajika, Masahiro, Fujiwara, Junko, Yamamoto, Yoshinobu, Katada, Chikatoshi, Hori, Shinichiro, Doyama, Hisashi, Oyama, Tsuneo, Nebiki, Hiroko, Amagai, Kenji, Kubota, Yutaro, Nishimura, Ken, Kobayashi, Nozomu, Suzuki, Takuto, Hirasawa, Kingo, Takeuchi, Toshihisa, Fukuda, Haruhiko, and Muto, Manabu

Published
2019
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22. E-learning system to improve the endoscopic diagnosis of early gastric cancer.

Author

Yao, Kenshi, Yao, Takashi, Uedo, Noriya, Doyama, Hisashi, Ishikawa, Hideki, Nimura, Satoshi, and Takahashi, Yuichi

Subjects
STOMACH cancer, DIGITAL learning, EARLY diagnosis, CANCER diagnosis, AUTODIDACTICISM
Abstract

We developed three e-learning systems for endoscopists to acquire the necessary skills to improve the diagnosis of early gastric cancer (EGC) and demonstrated their usefulness using randomized controlled trials. The subjects of the three e-learning systems were "detection", "characterization", and "preoperative assessment". The contents of each e-learning system included "technique", "knowledge", and "obtaining experience". All e-learning systems proved useful for endoscopists to learn how to diagnose EGC. Lecture videos describing "the technique" and "the knowledge" can be beneficial. In addition, repeating 100 self-study cases allows learners to gain "experience" and improve their diagnostic skills further. Web-based e-learning systems have more advantages than other teaching methods because the number of participants is unlimited. Histopathological diagnosis is the gold standard for the diagnosis of gastric cancer. Therefore, we developed a comprehensive diagnostic algorithm to standardize the histopathological diagnosis of gastric cancer. Once we have successfully shown that this algorithm is helpful for the accurate histopathological diagnosis of cancer, we will complete a series of e-learning systems designed to assess EGC accurately. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Alcohol consumption, multiple Lugol‐voiding lesions, and field cancerization.

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Suzuki, Haruhisa, Furue, Yasuaki, Yamamoto, Keiko, Doyama, Hisashi, Koike, Tomoyuki, Tamaoki, Masashi, Kawata, Noboru, Hirao, Motohiro, Kawahara, Yoshiro, Ogata, Takashi, Katagiri, Atsushi, Yamanouchi, Takenori, Kiyokawa, Hirofumi, Kawakubo, Hirofumi, Konno, Maki, Yokoyama, Akira, and Ohashi, Shinya

Published
2024
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25. Results of the interim analysis of a prospective, multicenter, observational study of small subepithelial lesions in the stomach.

Author

Iwamuro, Masaya, Mitsuhashi, Toshiharu, Inaba, Tomoki, Matsueda, Kazuhiro, Nagahara, Teruya, Takeuchi, Yoji, Doyama, Hisashi, Mizuno, Masakatsu, Yada, Tomoyuki, Kawai, Yoshinari, Nakamura, Jun, Matsubara, Minoru, Nebiki, Hiroko, Niimi, Keiko, Toyokawa, Tatsuya, Takenaka, Ryuta, Takeda, Sho, Tanaka, Shouichi, Nishimura, Mamoru, and Tsuzuki, Takao

Subjects
SCIENTIFIC observation, STOMACH, NATURAL history, TUMOR surgery, GASTROINTESTINAL stromal tumors
Abstract

Objectives: Long‐term outcomes of gastric subepithelial lesions have not been elucidated. To reveal the natural history, we initiated a prospective, 10‐year follow‐up of patients with small (≤20 mm) gastric subepithelial lesions in September 2014. Here, we report the results of an interim analysis of a prospective observational study. Methods: In total, 567 patients with 610 lesions were prospectively registered between September 2014 and August 2016. The location, size, morphology, and number of subepithelial lesions were recorded on a web‐based case report form. This study has been conducted as an Academic Committee Working Group of the Japan Gastroenterological Endoscopy Society. Results: The endoscopic follow‐up period was 4.60 ± 1.73 years (mean ± standard deviation), and survival data were investigated for 5.28 ± 1.68 years. This interim analysis revealed that the estimated cumulative incidence of a size increase ≥5 mm, after accounting for patients' death and resection of the tumor as competing risk events, was 4.5% at 5 years. In addition, the estimated cumulative incidence of lesion size increase ≥5 mm or resection of lesions was 7.9% at 5 years, and that of size increase ≥10 mm or resection of lesions was 4.5% at 5 years. Conclusion: These results indicate that approximately one in 13 patients with small (≤20 mm) gastric subepithelial lesions may require resection or further investigation for increased tumor size (≥5 mm) within 5 years. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Risk Factors for Bleeding After Endoscopic Submucosal Dissection for Gastric Cancer in Elderly Patients Older Than 80 Years in Japan

Author

Sugimoto, Mitsushige, Hatta, Waku, Tsuji, Yosuke, Yoshio, Toshiyuki, Yabuuchi, Yohei, Hoteya, Shu, Doyama, Hisashi, Nagami, Yasuaki, Hikichi, Takuto, Kobayashi, Masakuni, Morita, Yoshinori, Sumiyoshi, Tetsuya, Iguchi, Mikitaka, Tomida, Hideomi, Inoue, Takuya, Mikami, Tatsuya, Hasatani, Kenkei, Nishikawa, Jun, Matsumura, Tomoaki, Nebiki, Hiroko, Nakamatsu, Dai, Ohnita, Ken, Suzuki, Haruhisa, Ueyama, Hiroya, Hayashi, Yoshito, Murata, Masaki, Yamaguchi, Shinjiro, Michida, Tomoki, Yada, Tomoyuki, Asahina, Yoshiro, Narasaka, Toshiaki, Kuribayashi, Shiko, Kiyotoki, Shu, Mabe, Katsuhiro, Fujishiro, Mitsuhiro, Masamune, Atsushi, and Kawai, Takashi

Published
2021
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27. Clinical Guidelines for Diagnosis and Management of Cowden Syndrome/PTEN Hamartoma Tumor Syndrome in Children and Adults-Secondary Publication

Author

Takayama, Tetsuji, primary, Muguruma, Naoki, additional, Igarashi, Masahiro, additional, Ohsumi, Shozo, additional, Oka, Shiro, additional, Kakuta, Fumihiko, additional, Kubo, Yoshiaki, additional, Kumagai, Hideki, additional, Sasaki, Mika, additional, Sugai, Tamotsu, additional, Sugano, Kokichi, additional, Takeda, Yuko, additional, Doyama, Hisashi, additional, Banno, Kouji, additional, Fukahori, Suguru, additional, Furukawa, Yoichi, additional, Horimatsu, Takahiro, additional, Ishikawa, Hideki, additional, Iwama, Takeo, additional, Okazaki, Yasushi, additional, Saito, Yutaka, additional, Matsuura, Nariaki, additional, Mutoh, Michihiro, additional, Tomita, Naohiro, additional, Akiyama, Takashi, additional, Yamamoto, Toshiki, additional, Ishida, Hideyuki, additional, and Nakayama, Yoshiko, additional

Published
2023
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28. Efficacy of endoscopic submucosal resection with a ligation device for small rectal neuroendocrine tumor: study protocol of a multicenter open-label randomized control trial (BANDIT trial)

Author

Takada, Kazunori, primary, Imai, Kenichiro, additional, Yamada, Takanori, additional, Ohata, Ken, additional, Kanesaka, Takashi, additional, Nagami, Yasuaki, additional, Yamasaki, Yasushi, additional, Kobara, Hideki, additional, Inokuchi, Yasuhiro, additional, Chino, Akiko, additional, Yamaguchi, Shinjiro, additional, Ikehara, Hisatomo, additional, Kawamura, Takuji, additional, Yabuuchi, Yohei, additional, Mizuguchi, Yasuhiko, additional, Ikematsu, Hiroaki, additional, Yokoi, Chizu, additional, Hattori, Santa, additional, Ohno, Kazuya, additional, Yoshizawa, Yashiro, additional, Fukuzawa, Masakatsu, additional, Tsuji, Yosuke, additional, Konishi, Jun, additional, Yamamura, Takeshi, additional, Osawa, Satoshi, additional, Oka, Shiro, additional, Hikichi, Takuto, additional, Togashi, Kazutomo, additional, Hirasawa, Kingo, additional, Uraoka, Toshio, additional, Takeuchi, Yoji, additional, Chiba, Hideyuki, additional, Komeda, Yoriaki, additional, Doyama, Hisashi, additional, Oba, Mari S, additional, and Saito, Yutaka, additional

Published
2023
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32. Alcohol consumption, multiple Lugol‐voiding lesions, and field cancerization

Author

Katada, Chikatoshi, primary, Yokoyama, Tetsuji, additional, Yano, Tomonori, additional, Suzuki, Haruhisa, additional, Furue, Yasuaki, additional, Yamamoto, Keiko, additional, Doyama, Hisashi, additional, Koike, Tomoyuki, additional, Tamaoki, Masashi, additional, Kawata, Noboru, additional, Hirao, Motohiro, additional, Kawahara, Yoshiro, additional, Ogata, Takashi, additional, Katagiri, Atsushi, additional, Yamanouchi, Takenori, additional, Kiyokawa, Hirofumi, additional, Kawakubo, Hirofumi, additional, Konno, Maki, additional, Yokoyama, Akira, additional, Ohashi, Shinya, additional, Kondo, Yuki, additional, Kishimoto, Yo, additional, Kano, Koichi, additional, Mure, Kanae, additional, Hayashi, Ryuichi, additional, Ishikawa, Hideki, additional, and Muto, Manabu, additional

Published
2023
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33. Results of the interim analysis of a prospective, multicenter, observational study of small subepithelial lesions in the stomach

Author

Iwamuro, Masaya, primary, Mitsuhashi, Toshiharu, additional, Inaba, Tomoki, additional, Matsueda, Kazuhiro, additional, Nagahara, Teruya, additional, Takeuchi, Yoji, additional, Doyama, Hisashi, additional, Mizuno, Masakatsu, additional, Yada, Tomoyuki, additional, Kawai, Yoshinari, additional, Nakamura, Jun, additional, Matsubara, Minoru, additional, Nebiki, Hiroko, additional, Niimi, Keiko, additional, Toyokawa, Tatsuya, additional, Takenaka, Ryuta, additional, Takeda, Sho, additional, Tanaka, Shouichi, additional, Nishimura, Mamoru, additional, Tsuzuki, Takao, additional, Akahoshi, Kazuya, additional, Furuta, Takahisa, additional, Haruma, Ken, additional, and Okada, Hiroyuki, additional

Published
2023
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34. Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter prospective interventional study

Author

Ishikawa, Hideki, Yamada, Masayoshi, Sato, Yasushi, Tanaka, Shinji, Chino, Akiko, Tajika, Masahiro, Doyama, Hisashi, Takayama, Tetsuji, Ohda, Yoshio, Horimatsu, Takahiro, Sano, Yasushi, Tanakaya, Kohji, Ikematsu, Hiroaki, Saida, Yoshihisa, Ishida, Hideyuki, Takeuchi, Yoji, Kashida, Hiroshi, Kiriyama, Shinsuke, Hori, Shinichiro, Lee, Kyowon, Tashiro, Jun, Kobayashi, Nozomu, Nakajima, Takeshi, Suzuki, Sadao, and Mutoh, Michihiro

Subjects
Gastroenterology
Abstract

Background Total colectomy is the standard treatment for familial adenomatous polyposis (FAP). Recently, an increasing number of young patients with FAP have requested the postponement of surgery or have refused to undergo surgery. We aimed to evaluate the effectiveness of intensive endoscopic removal for downstaging of polyp burden (IDP) in FAP. Method A single-arm intervention study was conducted at 22 facilities. Participants were patients with FAP, aged ≥ 16 years, who had not undergone colectomy or who had undergone colectomy but had ≥ 10 cm of large intestine remaining. For IDP, colorectal polyps of ≥ 10 mm were removed, followed by polyps of ≥ 5 mm. The primary end point was the presence/absence of colectomy during a 5-year intervention period. Results 222 patients were eligible, of whom 166 had not undergone colectomy, 46 had undergone subtotal colectomy with ileorectal anastomosis, and 10 had undergone partial resection of the large intestine. During the intervention period, five patients (2.3 %, 95 % confidence interval [CI] 0.74 %–5.18 %) underwent colectomy, and three patients died. Completion of the 5-year intervention period without colectomy was confirmed in 150 /166 patients who had not undergone colectomy (90.4 %, 95 %CI 84.8 %–94.4 %) and in 47 /56 patients who had previously undergone colectomy (83.9 %, 95 %CI 71.7 %–92.4 %). Conclusion IDP in patients with mild-to-moderate FAP could have the potential to be a useful means of preventing colorectal cancer without implementing colectomy. However, if the IDP protocol was proposed during a much longer term, it may not preclude the possibility that a large proportion of colectomies may still need to be performed.

Published
2022

37. A non-randomized confirmatory trial of an expanded indication for endoscopic submucosal dissection for intestinal-type gastric cancer (cT1a): the Japan Clinical Oncology Group study (JCOG0607)

Author

Hasuike, Noriaki, Ono, Hiroyuki, Boku, Narikazu, Mizusawa, Junki, Takizawa, Kohei, Fukuda, Haruhiko, Oda, Ichiro, Doyama, Hisashi, Kaneko, Kazuhiro, Hori, Shinichiro, Iishi, Hiroyasu, Kurokawa, Yukinori, Muto, Manabu, and Gastrointestinal Endoscopy Group of Japan Clinical Oncology Group (JCOG-GIESG)

Published
2018
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38. Radiation dose and factors related to exceeding the diagnostic reference level in 496 transnasal ileus tube placement procedures from the REX-GI study

Author

Nagaike, Koji, primary, Hayashi, Shiro, additional, Yakushijin, Takayuki, additional, Yamamoto, Masashi, additional, Sumiyoshi, Tetsuya, additional, Yamaguchi, Shinjiro, additional, Tamaru, Yuzuru, additional, Yamada, Takuya, additional, Tsumura, Hidetaka, additional, Nakai, Yousuke, additional, Doyama, Hisashi, additional, Maetani, Iruru, additional, Takagi, Tadayuki, additional, Asai, Satoshi, additional, Matsubara, Kosuke, additional, Takenaka, Mamoru, additional, Hosono, Makoto, additional, and Nishida, Tsutomu, additional

Published
2023
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39. Data from Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients

Author

Mure, Kanae, primary, Ishikawa, Hideki, primary, Mutoh, Michihiro, primary, Horinaka, Mano, primary, Otani, Takahiro, primary, Suzuki, Sadao, primary, Wakabayashi, Keiji, primary, Sakai, Toshiyuki, primary, Sato, Yasushi, primary, Doyama, Hisashi, primary, Tajika, Masahiro, primary, Tanaka, Shinji, primary, Horimatsu, Takahiro, primary, Takeuchi, Yoji, primary, Kashida, Hiroshi, primary, Tashiro, Jun, primary, Ezoe, Yasumasa, primary, Nakajima, Takeshi, primary, Ikematsu, Hiroaki, primary, Hori, Shinichiro, primary, Takayama, Tetsuji, primary, and Ohda, Yoshio, primary

Published
2023
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40. Supplementary Data from Efficacy of Low-Dose Aspirin in Colorectal Cancer Risk Prevention is Dependent on ADH1B and ALDH2 Genotype in Japanese Familial Adenomatous Polyposis Patients

Author

Mure, Kanae, primary, Ishikawa, Hideki, primary, Mutoh, Michihiro, primary, Horinaka, Mano, primary, Otani, Takahiro, primary, Suzuki, Sadao, primary, Wakabayashi, Keiji, primary, Sakai, Toshiyuki, primary, Sato, Yasushi, primary, Doyama, Hisashi, primary, Tajika, Masahiro, primary, Tanaka, Shinji, primary, Horimatsu, Takahiro, primary, Takeuchi, Yoji, primary, Kashida, Hiroshi, primary, Tashiro, Jun, primary, Ezoe, Yasumasa, primary, Nakajima, Takeshi, primary, Ikematsu, Hiroaki, primary, Hori, Shinichiro, primary, Takayama, Tetsuji, primary, and Ohda, Yoshio, primary

Published
2023
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41. A follow‐up questionnaire survey 2022 on radiation protection among 464 medical staff from 34 endoscopy–fluoroscopy departments in Japan

Author

Hayashi, Shiro, primary, Takenaka, Mamoru, additional, Kogure, Hirofumi, additional, Yakushijin, Takayuki, additional, Nakai, Yousuke, additional, Ikezawa, Kenji, additional, Yamaguhci, Shinjiro, additional, Fujisawa, Toshio, additional, Tamaru, Yuzuru, additional, Maetani, Iruru, additional, Maruyama, Hirotsugu, additional, Asai, Satoshi, additional, Takagi, Tadayuki, additional, Nagaike, Koji, additional, Hori, Yasuki, additional, Sumiyoshi, Tetsuya, additional, Tsumura, Hidetaka, additional, Doyama, Hisashi, additional, Yoshio, Toshiyuki, additional, Hara, Kazuo, additional, Abe, Seiichiro, additional, Oda, Ichiro, additional, Kato, Motohiko, additional, Nebiki, Hiroko, additional, Mikami, Tatsuya, additional, Miyazaki, Masanori, additional, Matsunaga, Kazuhiro, additional, Hosono, Makoto, additional, Nishida, Tsutomu, additional, Egawa, Satoshi, additional, Nishihara, Akihiro, additional, Ohnita, Ken, additional, Minami, Ryuki, additional, Tada, Naoya, additional, Kobayashi, Katsumasa, additional, and Kato, Masayuki, additional

Published
2023
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42. Alcohol Consumption and Multiple Dysplastic Lesions Increase Risk of Squamous Cell Carcinoma in the Esophagus, Head, and Neck

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Kaneko, Kazuhiro, Oda, Ichiro, Shimizu, Yuichi, Doyama, Hisashi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Okada, Hiroyuki, Yoshii, Takako, Konishi, Kazuo, Yamanouchi, Takenori, Tsuda, Takashi, Omori, Tai, Kobayashi, Nozomu, Shimoda, Tadakazu, Ochiai, Atsushi, Amanuma, Yusuke, Ohashi, Shinya, Matsuda, Tomonari, Ishikawa, Hideki, Yokoyama, Akira, and Muto, Manabu

Published
2016
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43. Risk factors for the development of second primary esophageal squamous-cell carcinoma after endoscopic resection for esophageal squamous-cell carcinoma according to genetic polymorphisms related to alcohol and nicotine metabolism.

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Mure, Kanae, Doyama, Hisashi, Nakanishi, Hiroyoshi, Shimizu, Yuichi, Yamamoto, Keiko, Furue, Yasuaki, Tamaoki, Masashi, Koike, Tomoyuki, Kawahara, Yoshiro, Kiyokawa, Hirofumi, Konno, Maki, Yokoyama, Akira, Ohashi, Shinya, Ishikawa, Hideki, and Muto, Manabu

Published
2023
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44. Final Analysis of Diagnostic Endoscopic Resection Followed by Selective Chemoradiotherapy for Stage I Esophageal Cancer: JCOG0508

Author

Nihei, Keiji, primary, Minashi, Keiko, additional, Yano, Tomonori, additional, Shimoda, Tadakazu, additional, Fukuda, Haruhiko, additional, Muto, Manabu, additional, Mizuaswa, Junki, additional, Takizawa, Kohei, additional, Aoyama, Ikuo, additional, Ishiyama, Akiyoshi, additional, Kawata, Noboru, additional, Kikuchi, Daisuke, additional, Hanaoka, Noboru, additional, Oda, Ichiro, additional, Morita, Yoshinori, additional, Tajika, Masahiro, additional, Fujiwara, Junko, additional, Yamamoto, Yoshinobu, additional, Katada, Chikatoshi, additional, Hori, Shinichiro, additional, Doyama, Hisashi, additional, Oyama, Tsuneo, additional, Nebiki, Hiroko, additional, Amagai, Kenji, additional, Kubota, Yutaro, additional, Inokuchi, Yasuhiro, additional, Kobayashi, Nozomu, additional, Suzuki, Takuto, additional, Hirasawa, Kingo, additional, Takeuchi, Toshihisa, additional, and Kadota, Tomohiro, additional

Published
2023
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45. Non-atrophic gastric mucosa is an independently associated factor for superficial non-ampullary duodenal epithelial tumors: a multicenter, matched, case-control study

Author

Kawasaki, Azusa, primary, Tsuji, Kunihiro, additional, Uedo, Noriya, additional, Kanesaka, Takashi, additional, Miyamoto, Hideaki, additional, Gushima, Ryosuke, additional, Minoda, Yosuke, additional, Ihara, Eikichi, additional, Amano, Ryosuke, additional, Yao, Kenshi, additional, Naito, Yoshihide, additional, Aoyagi, Hiroyuki, additional, Iwasaki, Takehiro, additional, Uchita, Kunihisa, additional, Arima, Hisatomi, additional, and Doyama, Hisashi, additional

Published
2023
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49. 288. ASSOCIATION BETWEEN ENDOGENOUS SUBTYPE CLASSIFICATION FOR ESOPHAGEAL SQUAMOUS CELL CARCINOMA AND OUTCOME OF CHEMORADIOTHERAPY

Author

Yano, Tomonori, primary, Amanuma, Yusuke, additional, Minashi, Keiko, additional, Komatsu, Masayuki, additional, Nagashima, Kengo, additional, Shimizu, Juko, additional, Ishihara, Ryu, additional, Watanabe, Akinori, additional, Yamatsuji, Tomoki, additional, Matsushima, Kayoko, additional, Doyama, Hisashi, additional, Ando, Takayuki, additional, Nishimura, Yasumasa, additional, Sasaki, Hiroki, additional, and Muto, Manabu, additional

Published
2022
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50. A multicenter, randomized controlled trial comparing the identification rate of stigmata of recent hemorrhage and rebleeding rate between early and elective colonoscopy in outpatient-onset acute lower gastrointestinal bleeding: study protocol for a randomized controlled trial

Author

Niikura, Ryota, Nagata, Naoyoshi, Yamada, Atsuo, Doyama, Hisashi, Shiratori, Yasutoshi, Nishida, Tsutomu, Kiyotoki, Shu, Yada, Tomoyuki, Fujita, Tomoki, Sumiyoshi, Tetsuya, Hasatani, Kenkei, Mikami, Tatsuya, Honda, Tetsuro, Mabe, Katsuhiro, Hara, Kazuo, Yamamoto, Katsumi, Takeda, Mariko, Takata, Munenori, Tanaka, Mototsugu, Shinozaki, Tomohiro, Fujishiro, Mitsuhiro, and Koike, Kazuhiko

Published
2018
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