252 results on '"Douglas, James J."'
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2. An Intramolecular Diels–Alder Approach to the Isoindolinone Core of AZD8154
3. Copper-catalysed amination of alkyl iodides enabled by halogen-atom transfer
4. A unified flow strategy for the preparation and use of trifluoromethyl-heteroatom anions.
5. Synthesis and Suzuki–Miyaura Cross-Coupling of Alkyl Amine-Boranes. A Boryl Radical-Enabled Strategy.
6. Analysis of the Change in Molecular Complexity of Reaction Products in Process Development Activities at AstraZeneca Over Time.
7. A photochemical dehydrogenative strategy for aniline synthesis
8. NHCs in organocatalysis : azolium enolate generation and synthetic applications
9. Practical and regioselective amination of arenes using alkyl amines
10. Some Items of Interest to Process R&D Chemists and Engineers
11. Enantioselective NHC-catalysed redox [4+2]-hetero-Diels-Alder reactions using α-aroyloxyaldehydes and unsaturated ketoesters
12. Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on a Kilogram Scale
13. Visible-Light Photocatalysis Academic–Industrial Collaboration Retrospective: Shared Learning and Impact Analysis
14. Improving the sustainability of the ruthenium-catalysed N-directed C–H arylation of arenes with aryl halides
15. Some Items of Interest to Process R&D Chemists and Engineers
16. Correction to “Some Items of Interest to Process R&D Chemists and Engineers”
17. A display of sensitivity
18. Some Items of Interest to Process R&D Chemists and Engineers
19. The Merger of Aryl Radical-Mediated Halogen-Atom Transfer (XAT) and Copper Catalysis for the Modular Cross-Coupling-Type Functionalization of Alkyl Iodides.
20. A Desaturative Approach for Aromatic Aldehyde Synthesis via Synergistic Enamine, Photoredox and Cobalt Triple Catalysis
21. First Deliveries of API Enabling Early Drug Development.
22. Some Items of Interest to Process R&D Chemists and Engineers
23. Exploration of a Nitromethane-Carbonylation Strategy during Route Design of an Atropisomeric KRASG12C Inhibitor
24. Photocatalysis in the Life Science Industry
25. A dual photoredox-nickel strategy for remote functionalization via iminyl radicals: radical ring-opening-arylation, -vinylation and -alkylation cascades† †Electronic supplementary information (ESI) available: Full experimental details and characterisation. See DOI: 10.1039/c9sc02616a
26. Sepsis and the innate-like response
27. Some Items of Interest to Process R&D Chemists and Engineers
28. Radical hydroxymethylation of alkyl iodides using formaldehyde as a C1 synthon
29. Development and Proof of Concept for a Large-Scale Photoredox Additive-Free Minisci Reaction
30. Some Items of Interest to Process R&D Chemists and Engineers
31. Some Items of Interest to Process R&D Chemists and Engineers
32. Exploration of a Nitromethane-Carbonylation Strategy during Route Design of an Atropisomeric KRASG12C Inhibitor.
33. Metabolic changes in cardiomyocytes during sepsis
34. Correction: A dual photoredox-nickel strategy for remote functionalization via iminyl radicals: radical ring-opening-arylation, -vinylation and -alkylation cascades
35. Photoinduced decarboxylative azidation of cyclic amino acids
36. Multikilogram-Scale Preparation of AZD4635 via C–H Borylation and Bromination: The Corrosion of Tantalum by a Bromine/Methanol Mixture
37. Stereo- and Chemodivergent NHC-Promoted Functionalisation of Arylalkylketenes with Chloral**
38. Development and Proof of Concept for a Large-Scale Photoredox Additive-Free Minisci Reaction.
39. Visible-Light-Mediated 5-exo-dig Cyclizations of Amidyl Radicals
40. Photoinduced Remote Functionalizations via Iminyl Radical- Promoted C–C and C–H Bond Cleavage Cascades
41. Ligand functionalization as a deactivation pathway in a fac-Ir(ppy)3-mediated radical addition† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03064h Click here for additional data file
42. Photoinduced Remote Functionalization of Amides and Amines Using Electrophilic Nitrogen Radicals
43. Frontispiece: Hydroxylamine Derivatives as Nitrogen-Radical Precursors in Visible-Light Photochemistry
44. Hydroxylamine Derivatives as Nitrogen-Radical Precursors in Visible-Light Photochemistry
45. The Application of Visible‐Light‐Mediated Reactions to the Synthesis of Pharmaceutical Compounds
46. Photoinduced Remote Functionalisations by Iminyl Radical Promoted C−C and C−H Bond Cleavage Cascades
47. Photoinduced Remote Functionalisations by Iminyl Radical Promoted C−C and C−H Bond Cleavage Cascades
48. Visible-Light-Mediated Reactions of Electrophilic Radicals with Vinyl and Allyl Trifluoroborates
49. Visible-Light-Mediated 5-exo -dig Cyclizations of Amidyl Radicals
50. Multikilogram-Scale Preparation of AZD4635 via C–H Borylation and Bromination: The Corrosion of Tantalum by a Bromine/Methanol Mixture.
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