146 results on '"Dou, Zhixun"'
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2. Apoptotic stress causes mtDNA release during senescence and drives the SASP
3. Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML
4. Treatment of calcific arterial disease via enhancement of autophagy using GSK343
5. Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP
6. SIRT1 is downregulated by autophagy in senescence and ageing
7. Loss of epigenetic information as a cause of mammalian aging
8. Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform
9. Loss of epigenetic information as a cause of mammalian aging
10. Apolipoprotein E regulates chromatin stability and senescence
11. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus
12. A mitochondria-regulated p53-CCF circuit integrates genome integrity with inflammation
13. Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection
14. P471: POLO-LIKE KINASE 4 INHIBITION INDUCED ANTI-LEUKAEMIC EFFECTS THROUGH HISTONE MODIFICATION IN TP53 MUTATED ACUTE MYELOID LEUKAEMIA
15. Targeting PI3-Kinases in Modulating Autophagy and Anti-cancer Therapy
16. Lysine methylation represses p53 activity in teratocarcinoma cancer cells
17. SenNet recommendations for detecting senescent cells in different tissues
18. Cytoplasmic chromatin triggers inflammation in senescence and cancer
19. Nuclear autophagy interactome unveils WSTF as a constitutive nuclear inhibitor of inflammation
20. Upregulation of PD-L1 in Senescence and Aging
21. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-l—like receptor-mediated innate immune response
22. Autophagy mediates degradation of nuclear lamina
23. Senescence Elicits Stemness: A Surprising Mechanism for Cancer Relapse
24. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
25. Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
26. Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP
27. Targeting PI3-Kinases in Modulating Autophagy and Anti-cancer Therapy
28. The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy
29. Loss of TBK1 activity leads to TDP-43 proteinopathy through lysosomal dysfunction in human motor neurons
30. The class IA phosphatidylinositol 3-kinase p110-[beta] subunit is a positive regulator of autophagy
31. Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection
32. Loss of Epigenetic Information as a Cause of Mammalian Aging
33. SIRT1 – a new mammalian substrate of nuclear autophagy
34. Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence
35. Erosion of the Epigenetic Landscape and Loss of Cellular Identity as a Cause of Aging in Mammals
36. Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence
37. SIRT1 – a new mammalian substrate of nuclear autophagy.
38. Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress
39. TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis
40. MLL1 is essential for the senescence-associated secretory phenotype
41. Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 Complex
42. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I–like receptor-mediated innate immune response
43. Class IA PI3K p110β Subunit Promotes Autophagy through Rab5 Small GTPase in Response to Growth Factor Limitation
44. Mammalian PIK3C3/VPS34
45. Inhibition of Protein Degradation Induces Apoptosis through a Microtubule-Associated Protein 1 Light Chain 3-Mediated Activation of Caspase-8 at Intracellular Membranes
46. The beta identity of class I PtdIns3K
47. The Calponin Homology Domain of Vav1 Associates with Calmodulin and Is Prerequisite to T Cell Antigen Receptor-induced Calcium Release in Jurkat T Lymphocytes
48. Linked regulation of genome integrity and senescence-associated inflammation by p53.
49. Limiting the impact of protein leakage in single-cell proteomics.
50. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response.
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