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5 results on '"Dote M"'

1. Accelerator system at the Wakasa-wan Energy Research Center.

Author

Hatori, S., Ito, Y., Ishigami, R., Yasuda, K., Inomata, T., Maruyama, T., Ikezawa, K., Takagi, K., Yamamoto, K., Fukuda, S., Kume, K., Kagiya, G., Hasegawa, T., Hatashita, M., Yamada, M., Yamada, H., Dote, M., Ohtani, N., Kakiuchi, S., and Tominaga, Y.

Subjects
ION accelerators, ENERGY research
Abstract

At Wakasa-wan Energy Research Center, Fukui, Japan, the accelerator system is now under construction. The system consists of a 200 keV ion implanter, a 5 MV Schenckel type tandem accelerator and a 200 MeV proton synchrotron. The ion implanter is for the improvement of the surface of the material. By using the tandem accelerator, we can perform the element analysis, the improvement of the bio-species and ion-implantation into various materials. The tandem accelerator works as an injector for the synchrotron and the synchrotron is for the cancer therapy and also bio and material science. [ABSTRACT FROM AUTHOR]

Published
2001

3. Successful diagnosis of a localized liver tumor via transjugular liver biopsy after ascites hampered a percutaneous approach.

Author

Hamaguchi S, Nakashima Y, Dote M, Wada S, Hashimoto K, and Mimura H

Abstract

Liver biopsy is a crucial diagnostic procedure for liver-related conditions. However, it is challenging to use in cases with substantial ascites or coagulopathy. Transjugular liver biopsy has been introduced as an alternative method to overcome these limitations. Although transjugular liver biopsy is commonly used for diffuse liver diseases, its application to localized tumors has been limited. We report the case of a 66-year-old male initially diagnosed with unresectable pancreatic carcinoma, who later developed liver metastasis, peritoneal dissemination, and ascites. Treatment planning required tumor re-evaluation, but percutaneous liver biopsy was not viable because of the rapid accumulation of ascites and its presence on the liver surface. However, transjugular liver biopsy was a suitable alternative, given the proximity of the tumor to the right hepatic vein. The procedure, performed under fluoroscopic and ultrasound guidance, successfully obtained 4 specimens that were promptly diagnosed as liver metastases originating from pancreatic cancer. This case underscored the effectiveness of transjugular liver biopsy in situations where percutaneous biopsy is challenging because of conditions such as ascites. The combination of ultrasound guidance and rapid specimen assessment by pathology technicians can enhance diagnostic success rates. Transjugular liver biopsy is a valuable diagnostic tool in scenarios where percutaneous access poses significant difficulties., (© 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)

Published
2023
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4. [Scanning electron microscopic observation of the collagen fibrillar network in Bruch's membrane by cell maceration].

Author

Matsuoka T, Matsuo N, Nakagawa H, and Dote M

Subjects
Animals, Basement Membrane ultrastructure, Histological Techniques, Macaca, Microscopy, Electron, Scanning, Pigment Epithelium of Eye ultrastructure, Rabbits, Choroid ultrastructure, Collagen ultrastructure
Abstract

Cellular elements, including retinal pigment epithelia, were removed by the cell maceration method to obtain a three-dimensional view of the collagen fibrillar networks of Bruch's membrane. A bird's eye view of the inner collagenous zone of Bruch's membrane was obtained using the eyes of albino rabbits and Japanese monkeys. The eyes were treated with a low concentration of NaOH for several days and then observed with a scanning electron microscope. This procedure allowed the exposed inner collagenous zone of Bruch's membrane to be observed. In addition, the outer collagenous zone was also be observed in some of the specimens. Both zones were formed by dense lattices of fine collagen fibrils, and these fibrils frequently formed bundles in the outer collagenous zone. In the posterior poles of the eyes obtained from Japanese monkeys, a network of wavy fine collagen fibrils was observed. In both outer and inner collagenous zones, most of the collagen fibrils ran parallel to the retina. Fenestration of the sheet-like elastic layer was frequently observed through gaps in the thin collagen fibrillar network of the inner collagenous zone. The method employed in this study was considered suitable to obtain a wide bird's eye view of the collagenous zone of Bruch's membrane.

Published
1991

5. [Three-dimensional observation of elastic tissue in Bruch's membrane by formic acid extraction].

Author

Matsuoka T, Matsuo N, Nakagawa H, and Dote M

Subjects
Animals, Basement Membrane ultrastructure, Histological Techniques, Macaca, Microscopy, Electron, Scanning, Rabbits, Choroid ultrastructure, Elastic Tissue ultrastructure, Formates
Abstract

Japanese monkey and albino rabbit choroid were treated with hot-formic acid to remove the cellular elements and the extracellular matrices excluding the elastic tissues so that both three-dimensional and bird's eye views of the elastic layer of Bruch's membrane could be obtained. The only elastic layer was extracted and observed with a scanning electron microscope. Elastic layers were frequently extracted as translucent monolayered sheets with oval, sector-shaped fenestrations of varying sizes. Elastic fibers of 100-200nm in diameter crossed each other in these fenestrations. Other fine fibers connecting these elastic fibers and their sheet-like elastic plate were also observed. In Japanese monkey eyes, lattice structures formed by thick elastic fibers, 200-300nm in diameter, were conspicuous. This method proved suitable for the observation of the three-dimensional structure of the elastic layer of Bruch's membrane.

Published
1991

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