1,267 results on '"Dos, A. C."'
Search Results
2. EP-376 - DO BISTURI AO ALGORITMO: O INSTITUTO ADOLFO LUTZ REINVENTA A PATOLOGIA
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Carlos Pires F. Jr Takahashi, Juliana Possatto F. Takahashi, Paulo Sergio Padua de Lacerda, Cinthya dos Santos C. Borges, Camila Santos da Silva Ferreira, Juliana Mariotti Guerra, and Leonardo José Tadeu de Araujo
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Infectious and parasitic diseases ,RC109-216 ,Microbiology ,QR1-502 - Abstract
Introdução: Repositórios de amostras biológicas e bancos de dados ricos em informações impulsionam pesquisas inovadoras na área da saúde, catalisando estudos de ponta, validação de descobertas e colaboração global. Metadados detalhados garantem análises precisas, acesso facilitado a amostras e integração com outras fontes de dados, promovendo pesquisas inovadoras e impactantes. O renomado Instituto Adolfo Lutz (IAL), referência em saúde pública, abraça a era da Patologia Digital (PD) no Centro de Patologia (CP) em busca da excelência diagnóstica e do fomento à pesquisa de vanguarda. Objetivo: Através da implementação estratégica da PD, o CP-IAL se prepara para transformar a forma como o diagnóstico, o ensino e a pesquisa são realizados, impulsionando o avanço da medicina e contribuindo para o bem-estar da sociedade. Método: A implementação da PD será realizada de forma estratégica e gradual para garantir o sucesso da iniciativa e a otimização dos recursos disponíveis: (A) Análise profunda do fluxo de trabalho e dos recursos humanos, mapeando áreas de aprimoramento e oportunidades para a implementação da PD; (B) Desenvolvimento de um sistema piloto de armazenamento de dados (MySQL), alimentado por requisições, laudos e imagens emitidos a partir de 2017; (C) Uma aplicação web em PHP será desenvolvida para facilitar o acesso, cadastro, consulta e modificação das informações; (D) Aquisição de equipamentos de digitalização e softwares de análise de imagens; (E) treinamentos e capacitações internas; (F) Implementação piloto em áreas selecionadas e expansão gradual para outras áreas do CP-IAL. Resultados: A fase atual do projeto está focada no desenvolvimento do modelo relacional de dados, fundamental para organizar e representar as relações entre as informações. Inicialmente, foram utilizados dados de pacientes com diagnóstico clínico de Síndrome Respiratória Aguda Grave (SRAG), cujas amostras foram encaminhadas ao CP para identificação do agente etiológico. Conclusão: A implementação da Patologia Digital no Centro de Patologia do Instituto Adolfo Lutz trará resultados transformadores, como a redução do tempo de análise de amostras, maior precisão nos diagnósticos, telediagnóstico, fomento à pesquisa e modernização da infraestrutura, consolidando o CP-IAL como referência na era da medicina digital.
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- 2024
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3. The Molecular Basis of the Frank-Starling Law of the Heart: A Possible Role for PIEZO1?
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dos Remedios, C. G., Law, K. Y. C., McNamara, J. W., Kraft, T., Peckham, M., van der Velden, J., Linke, W. A., Ackerman, M., Sequeira, V., Lal, S., Cooke, R., Grosser, M., Campbell, K. S., Martinac, B., Li, A., Martinac, Boris, Series Editor, Cox, Charles D., editor, Poole, Kate, editor, Baratchi, Sara, editor, and Kempe, Daryan, editor
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- 2024
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4. The Molecular Basis of the Frank-Starling Law of the Heart: A Possible Role for PIEZO1?
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dos Remedios, C. G., primary, Law, K. Y. C., additional, McNamara, J. W., additional, Kraft, T., additional, Peckham, M., additional, van der Velden, J., additional, Linke, W. A., additional, Ackerman, M., additional, Sequeira, V., additional, Lal, S., additional, Cooke, R., additional, Grosser, M., additional, Campbell, K. S., additional, Martinac, B., additional, and Li, A., additional
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- 2024
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5. O PARTO DOMICILIAR PLANEJADO
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Diego Pereira Rodrigues, Laena Costa dos Reis, Leila Fernanda Silva de Oliveira, Valdecyr Herdy Alves, Giovanna Rosario Soanno Marchiori, Tatiana Socorro dos Santos C Calandrini, and Brenda Caroline Martins da Silva
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Mulheres ,Gravidez ,Parto Domiciliar ,Tocologia ,Serviços de Saúde. ,Nursing ,RT1-120 - Abstract
Objetivo: mapear os conceitos existentes em relação ao parto domiciliar planejado. Métodos: revisão de escopo realizada nas bases de dados em enfermagem: Medical Literature Analysisand Retrievel System Online, Cochrane Database of Systematic Reviews, Scopus, Cumulative Index to Nursing and Allied Health Literature e The Scientific Electronic Library Online. Resultados: obteve 15 estudos sobre o parto domiciliar planejado, retratando o perfil de mulheres e os desfechos maternos e neonatais, os profissionais de saúde na assistência ao parir em casa, com foco na expertise e qualificação, e a escolha e vivência das mulheres no parto domiciliar. Pois, o direito à informação qualificada para tomada de decisão da mulher constitui um alicerce para a efetivação do parto domiciliar planejado. Conclusão: tornam-se necessárias as políticas públicas que garantam o acesso e direito das mulheres em parir em domicílio, com apoio de profissionais de saúde qualificados, com foco no respeito, com assistência individualizada e integral.
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- 2024
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6. Effect of calcination on minimally processed recycled zirconia powder derived from milling waste
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Strazzi-Sahyon, H.B., Campos, T.M.B., dos Santos, C., Piza, M.M.T., Alves, L.M.M., Benalcazar Jalkh, E.B., Bergamo, E.T.P., Tebcherani, S.M., Witek, L., Coelho, P.G., Yamaguchi, S., and Bonfante, E.A.
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- 2024
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7. Magnetic properties and coupled spin‒phonon behavior of M‒type Sr1-xSmxFe12O19 (0 ≤ x ≤ 0.15) nanoparticles
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Buzinaro, M.A.P., dos Santos, C., Costa, B.F.O., Mâcedo, M.A., Matos, R.S., and Ferreira, N.S.
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- 2024
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8. Nuclear medicine technologists practice impacted by AI denoising applications in PET/CT images
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Champendal, M., Ribeiro, R.S.T., Müller, H., Prior, J.O., and Sá dos Reis, C.
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- 2024
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9. Approaches to reduce medical imaging departments’ environmental impact: A scoping review
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Ghotra, S.S., Champendal, M., Flaction, L., Ribeiro, R.T., and Sá dos Reis, C.
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- 2024
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10. TiO2-NPs/ZnO-NPs@Co3O4 nanocomposite from natural extracts for the Rhodamine 6 G photodegradation
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Wouters, R.D., Druzian, D.M., Muraro, P.C.L., da Silva, M.D.C.R., dos Santos, C., Ruiz, Y.P.M., Galembeck, A., Pavoski, G., Espinosa, D.C.R., and da Silva, W.L.
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- 2024
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11. Assessing nitrate groundwater hotspots in Europe reveals an inadequate designation of Nitrate Vulnerable Zones
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Serra, J., Marques-dos-Santos, C., Marinheiro, J., Cruz, S., Cameira, M.R., de Vries, W., Dalgaard, T., Hutchings, N.J., Graversgaard, M., Giannini-Kurina, F., Lassaletta, L., Sanz-Cobeña, A., Quemada, M., Aguilera, E., Medinets, S., Einarsson, R., and Garnier, J.
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- 2024
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12. Available Technical Options for Manure Management in Environmentally Friendly and Circular Livestock Production
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Marques-dos-Santos, C., Serra, J., Attard, G., Marchaim, U., Calvet, S., Amon, B., Berckmans, Daniel, Series Editor, Norton, Tomas, Series Editor, and Bartzanas, Thomas, editor
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- 2023
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13. Strategies enhancing the patient experience in mammography: A scoping review
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Ding, S., Fontaine, T., Serex, M., and Sá dos Reis, C.
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- 2024
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14. Alumni, radiographers, clinical placement tutors and industry insights about current radiographers practice, competences and autonomy in western Switzerland
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Sá dos Reis, C., De Labouchere, S., Campeanu, C., Ghotra, S.S., Flaction, L., Marmy, L., Vorlet, P., Al-Musibli, A., Franco, L., and Champendal, M.
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- 2024
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15. The queens of the stingless bees: from egg to adult
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Bueno, F. G. B., dos Santos, C. F., Otesbelgue, A., Menezes, C., van Veen, J., Blochtein, B., Gloag, R., Heard, T., Imperatriz-Fonseca, V. L., and Alves, D. A.
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- 2023
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16. Optimisation of exposure parameters using a phantom for thoracic spine radiographs in antero-posterior and lateral views
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Sá dos Reis, C., Caso, M., Dolenc, L., Howick, K., Lemmen, R., Meira, A., Shatku, F., Aymon, E., and Ghotra, S.S.
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- 2023
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17. Influence of Deep Cryogenic Treatment on the Pseudoelastic Behavior of the Ni57Ti43 Alloy
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Gontijo, M., da Silva, E. P., de Castro, M. C. S., dos Santos, C. T., and da Silva, T. C.
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- 2022
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18. Contributors
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Askari, Vahid Reza, primary, Aso, Ester, additional, Baradaran Rahimi, Vafa, additional, Baraibar, Andrés M., additional, Barnes, Robert, additional, Battini, Renata, additional, Bernal-Chico, Ana, additional, Bertoglio, Leandro José, additional, Best, Laura M., additional, Binda, Karina Henrique, additional, Boccella, Serena, additional, Boileau, Isabelle, additional, Bolkent, Sema, additional, Castro-Piedras, Isabel, additional, Chacur, Marucia, additional, Ciruela, Francisco, additional, Colomer, Teresa, additional, Corrêa, Moisés Dos Santos, additional, Correia-Sá, Inês, additional, Criscuolo, E., additional, Crombie, Kevin M., additional, Crosby, Karen M., additional, Cysneiros, Roberta Monterazzo, additional, da Silva, Ana P. dos Santos C. L, additional, da Silva, Bruna Vougado, additional, da Silva Lopes, Luciano, additional, da Silva Oliveira, George Laylson, additional, De Sciscio, M.L., additional, del Torrent, Claudia Llinás, additional, Diester, Clare M., additional, Dvorakova, Michaela, additional, Evans, José Fuentealba, additional, Faúndez Parraguez, Manuel, additional, Fezza, F., additional, Fornari, Raquel Vecchio, additional, Franco, Rafael, additional, Fu, Rao, additional, Fusco, Antimo, additional, Ganguly, Dipyaman, additional, Gazarini, Lucas, additional, Ghazali, Reem, additional, Glass, Michelle, additional, Gordon, Rita, additional, Gu, Xinyu, additional, Guindon, Josée, additional, Gyamfi, Daniel, additional, Heinbockel, Thomas, additional, Hellman, Judith, additional, Infantino, Rosmara, additional, Kabir, Morvarid, additional, Kandasamy, Ram, additional, Kassiou, Michael, additional, Kalinovsky, Anna, additional, Kitchigina, Valentina, additional, Koyama, Sachiko, additional, Leo, Eliana, additional, Liang, Jian, additional, Lillo, Jaume, additional, Lin, Yu-Fung, additional, Lloyd, Elliot, additional, Lu, Dai, additional, Maccarrone, M., additional, Mahabadi, Hajar Miranzadeh, additional, Maione, Sabatino, additional, Maldonado-Vlaar, Carmen S., additional, Manucha, Walter, additional, Maretti, Eleonora, additional, Martín Giménez, Virna M., additional, Martínez-Aguirre, Christopher, additional, Mato, Susana, additional, Matute, Carlos, additional, Mayo, Leah M., additional, McCormick, Cheryl M., additional, McHann, Melissa, additional, Mikheeva, Irina, additional, Molinari, Susanna, additional, Moreno-Garcia, Álvaro, additional, Navarro, Gemma, additional, Negus, S. Stevens, additional, Ney, Luke J., additional, Nguyen, Nina, additional, Niemela, Greta, additional, Norzé, Wickensonn, additional, Nuñez-Lumbreras, María de los Ángeles, additional, Palazzo, Enza, additional, Pan, Ying-Xian, additional, Patel, Vinood B., additional, Pecic, Stevan, additional, Perez-Valenzuela, Enzo, additional, Perrone, Michela, additional, Poluga, Claudia, additional, Poole, Emily I., additional, Preedy, Victor R., additional, Raïch, Iu, additional, Rajendram, Rajkumar, additional, Raymundi, Ana Maria, additional, Real, Caroline C, additional, Reekie, Tristan A., additional, Reyes-Resina, Irene, additional, Ribeiro, Fernanda Teixeira, additional, Rivas-Santisteban, Rafael, additional, Rocha, Luisa, additional, Sánchez, Ester, additional, Simone, Jonathan J., additional, Stern, Cristina Aparecida Jark, additional, Taghibiglou, Changiz, additional, Tam, Kelsey, additional, Tanaka, Mikiei, additional, Terry, Garth E., additional, Utrilla, Carmen L., additional, Varlow, Cassis, additional, Vasdev, Neil, additional, Wierenga, Corette J., additional, Woodward, John J., additional, Yazici, Zeynep Mine Coskun, additional, Ye, Jiang-Hong, additional, Zhang, Yumin, additional, and Zuo, Wanhong, additional
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- 2023
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19. Safety and toxicology of the dietary cannabinoid β-caryophyllene
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da Silva Oliveira, George Laylson, primary, da Silva, Bruna Vougado, additional, da Silva, Ana P. dos Santos C. L, additional, and da Silva Lopes, Luciano, additional
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- 2023
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20. P320 Impact of extended elexacaftor/tezacaftor/ivacaftor therapy on the gut microbiome in cystic fibrosis
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Marsh, R., primary, Dos Santos, C., additional, Yule, A., additional, Dellschaft, N.S., additional, Hoad, C.L., additional, Ng, C., additional, Major, G., additional, Smyth, A.R., additional, Rivett, D., additional, and van der Gast, C., additional
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- 2024
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21. THE AMETHYST (ADVANCED MESENCHYMAL ENHANCED CELL THERAPY FOR SEPTIC) TRIAL: A FIRST-IN-HUMAN, DOSE-ESCALATION PHASE 1 SAFETY TRIAL OF GENETICALLY ENHANCED MSCS (GEM00220) APPEARED SAFE AND WELL TOLERATED IN PATIENTS WITH SEPTIC SHOCK
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Mei, S.H., primary, Callahan, M., additional, dos Santos, C., additional, Marshall, J., additional, Soliman, K., additional, Sales, V., additional, Fernando, S., additional, Thirugnanam, S., additional, Stewart, D.J., additional, Champagne, J., additional, Whyte, J., additional, Watpool, I., additional, Tan, Y., additional, Salkhordeh, M., additional, Virgo, J., additional, Souza-Moreira, L., additional, and DesRosiers, E., additional
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- 2024
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22. Research ethics training, challenges, and suggested improvements across Europe: Radiography research ethics standards for Europe (RRESFE)
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Bockhold, S., McNulty, J., Abdurakman, E., Bezzina, P., Drey, N., England, A., Flinton, D., Khine, R., McEntee, M., Mekiš, N., Precht, H., Rainford, L., Sá dos Reis, C., Santos, A., Syrgiamiotis, V., Willis, S., Woodley, J., Beardmore, C., Harris, R., O'Regan, T., and Malamateniou, C.
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- 2022
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23. Research ethics systems, processes, and awareness across Europe: Radiography research ethics standards for Europe (RRESFE)
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Bockhold, S., McNulty, J., Abdurakman, E., Bezzina, P., Drey, N., England, A., Flinton, D., Khine, R., McEntee, M., Mekiš, N., Precht, H., Rainford, L., Sá dos Reis, C., Santos, A., Syrgiamiotis, V., Willis, S., Woodley, J., Beardmore, C., Harris, R., O'Regan, T., and Malamateniou, C.
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- 2022
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24. Comprehensive multi-cohort transcriptional meta-analysis of muscle diseases identifies a signature of disease severity
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Walsh, C. J., Batt, J., Herridge, M. S., Mathur, S., Bader, G. D., Hu, P., Khatri, P., and dos Santos, C. C.
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- 2022
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25. Nanosystems with potential application as carriers for skin depigmenting actives.
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Castro, Natalia Ruben, Pinto, Cristal Dos Santos C, Dos Santos, Elisabete P, and Mansur, Claudia Regina E
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LITERATURE reviews , *CHEMICAL peel , *NANOCARRIERS , *PRODUCT safety , *MELANOSIS - Abstract
Hyperpigmentation is a skin disorder characterized by excessive production of melanin in the skin and includes dyschromias such as post-inflammatory hyperchromias, lentigens, melasma and chloasma. Topical products containing depigmenting agents offer a less aggressive treatment option for hyperpigmentation compared to methods like chemical peels and laser sessions. However, some of these agents can cause side effects such as redness and skin irritation. Encapsulating these actives in nanosystems shows promise in mitigating these effects and improving product safety and efficacy. In addition, nanocarriers have the ability to penetrate the skin, potentially allowing for targeted delivery of actives to the affected areas. The most commonly investigated nanosystems are nanoemulsions, vesicular nanosystems and nanoparticles, in which different materials can be used to generate different compositions in order to improve the properties of these nanocarriers. Nanocarriers have already been widely explored, but it is necessary to understand the evolution of these technologies when applied to the treatment of skin hyperchromias. Therefore, this literature review aims to present the state of the art over the last 15 years on the use of nanosystems as a potential strategy for encapsulating depigmenting actives for potential application in cosmetic products for skin hyperchromia. By providing a comprehensive overview of the latest research findings and technological advances, this article can contribute to improving the care and quality of life of people affected by this skin condition. [ABSTRACT FROM AUTHOR]
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- 2024
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26. Autism-friendly MRI: Improving radiography practice in the UK, a survey of radiographer practitioners
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Stogiannos, N., Harvey–Lloyd, J.M., Nugent, B., Brammer, A., Carlier, S., Cleaver, K., McNulty, J.P., Sá dos Reis, C., and Malamateniou, C.
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- 2022
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27. A bibliometric review of peripartum cardiomyopathy compared to other cardiomyopathies using artificial intelligence and machine learning
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Grosser, M., Lin, H., Wu, M., Zhang, Y., Tipper, S., Venter, D., Lu, J., and dos Remedios, C. G.
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- 2022
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28. On the Order Parameter of the Continuous Phase Transition in the Classical and Quantum Mechanical Limits
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dos Santos, C. A. M., Oliveira, F. S., da Luz, M. S., and Neumeier, J. J.
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- 2021
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29. TiO2-NPs/ZnO-NPs@Co3O4 nanocomposite from natural extracts for the Rhodamine 6G photodegradation
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Wouters, R.D., primary, Druzian, D.M., additional, Muraro, P.C.L., additional, da Silva, M.D.C.R., additional, dos Santos, C., additional, Ruiz, Y.P.M., additional, Galembeck, A., additional, Pavoski, G., additional, Espinosa, D.C.R., additional, and da Silva, W.L., additional
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- 2024
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30. Well Integrity Management Based on New Operating Limits - A New Method for Extending the Well Lifespan and Changes in Operating Conditions
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Moreira, Nelson, additional, Lazaro, André F., additional, Minucci, F. R., additional, Aranha, Pedro E., additional, Weidlich, Marcos C., additional, Fernandes, Fernando B., additional, Nardi, Luiz F. B., additional, Radespiel, Eduardo S., additional, Okama, Charlton O., additional, Palmieri, I., additional, dos Santos, C. M., additional, and Terra, Felipe S., additional
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- 2024
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31. Changes in Skeletal Muscle Mass and Contractile Function
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Batt, J., dos Santos, C. C., Cecconi, Maurizio, Series Editor, De Backer, Daniel, Series Editor, Preiser, Jean-Charles, editor, Herridge, Margaret, editor, and Azoulay, Elie, editor
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- 2020
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32. Progressao sistematizada da dificuldade da tarefa pelo metodo shaping pode restringir o espaco de busca e direcionar o padrao de coordenacao em pessoas com hemiparesia cronica
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Marques, Fabiana da Silva, Pacheco, Matheus Maia, Gomes, Laura Helen dos Santos C., de Oliveira, Nayara Kelly, and Pereira, Natalia Duarte
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- 2023
33. 15.4.5 Quinolinones and Related Systems (Update 2022)
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Silva, V. L. M., additional, Pinto, D. C. G. A., additional, dos Santos, C. M. M., additional, and Rocha, D. H. A., additional
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- 2022
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34. AS VÁRIAS FORMAS DE PENSAR O LETRAMENTO PELOS ENFOQUES TEÓRICO E POLÍTICO-SOCIAL
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Oliveira, Patrícia dos S. C. de, primary
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- 2022
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35. Development of hybrid vesicular nanosystems composed of lipids and chitosan for octyl methoxycinnamate encapsulation
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Castro, Natalia Ruben, Pinto, Cristal dos Santos C., de Campos, Vânia Emerich B., Cardoso, Verônica, Vermelho, Alane Beatriz, Santos, Elisabete P. dos, and Mansur, Claudia Regina E.
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- 2021
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36. COVID-19 E SAUDE MENTAL DOS ADOLESCENTES: VULNERABILIDADES ASSOCIADAS AO USO DE INTERNET E MIDIAS SOCIAIS /MENTAL HEALTH OF TEENAGERS DURING THE COVID-19 PANDEMIC: VULNERABILITIES ASSOCIATED WITH THE USE OF THE INTERNET AND SOCIAL MEDIA
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dos Santos, C.
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- 2021
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37. Genomic and epidemiological monitoring of yellow fever virus transmission potential
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Faria, N. R., Kraemer, M. U. G., Hill, S. C., de Jesus, J. Goes, Aguiar, R. S., Iani, F. C. M., Xavier, J., Quick, J., du Plessis, L., Dellicour, S., Thézé, J., Carvalho, R. D. O., Baele, G., Wu, C.-H., Silveira, P. P., Arruda, M. B., Pereira, M. A., Pereira, G. C., Lourenço, J., Obolski, U., Abade, L., Vasylyeva, T. I., Giovanetti, M., Yi, D., Weiss, D. J., Wint, G. R. W., Shearer, F. M., Funk, S., Nikolay, B., Fonseca, V., Adelino, T. E. R., Oliveira, M. A. A., Silva, M. V. F., Sacchetto, L., Figueiredo, P. O., Rezende, I. M., Mello, E. M., Said, R. F. C., Santos, D. A., Ferraz, M. L., Brito, M. G., Santana, L. F., Menezes, M. T., Brindeiro, R. M., Tanuri, A., dos Santos, F. C. P., Cunha, M. S., Nogueira, J. S., Rocco, I. M., da Costa, A. C., Komninakis, S. C. V., Azevedo, V., Chieppe, A. O., Araujo, E. S. M., Mendonça, M. C. L., dos Santos, C. C., dos Santos, C. D., Mares-Guia, A. M., Nogueira, R. M. R., Sequeira, P. C., Abreu, R. G., Garcia, M. H. O., Abreu, A. L., Okumoto, O., Kroon, E. G., de Albuquerque, C. F. C., Lewandowski, K., Pullan, S. T., Carroll, M., de Oliveira, T., Sabino, E. C., Souza, R. P., Suchard, M. A., Lemey, P., Trindade, G. S., Drumond, B. P., Filippis, A. M. B., Loman, N. J., Cauchemez, S., Alcantara, L. C. J., and Pybus, O. G.
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- 2018
38. A Strategy Using Robotics to Assist in the Process of Teaching and Learning Kinematics.
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Almir de Oliveira Costa Junior, João dos Santos C. Neto, and Elloá B. Guedes
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- 2019
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39. Reduction of visual acuity decreases capacity to evaluate radiographic image quality
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Sá dos Reis, C., Soares, F., Bartoli, G., Dastan, K., Dhlamini, Z.S., Hussain, A., Kroode, D., McEntee, M.F., Mekis, N., and Thompson, J.D.
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- 2020
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40. Australasian radiographers’ choices of immobilisation strategies for paediatric radiological examinations
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Christie, S., Ng, C.K.C., and Sá dos Reis, C.
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- 2020
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41. Treatment of obstructive sleep apnea in children and adolescents with Down syndrome: systematic review and meta-analysis
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Fontes Ferreira, C.M., primary, Galvão dos Anjos, C. Pena, additional, Franco, L. Paiva, additional, Tinano, M. Maciel, additional, Nunes, F. Barbosa, additional, Torres, L. Lima, additional, Guerra Júnior, A.A., additional, Gargano, L. Peres, additional, Guimarães, R. Becker, additional, Pereira, M. Fontes, additional, Lima Bueno, J.V., additional, and Gonçalves Becker, H.M., additional
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- 2024
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42. (055) LRRC8A-VRAC Controls Superoxide Anion Flux in Diabetic Vasculogenic Erectile Dysfunction
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Vieira Dos Santos, C, primary, Rodrigues Dos Passos Jr., R, additional, Choi, H, additional, Panja, S, additional, Wilczynski, S, additional, Lamb, F, additional, Facholi Bomfim, G, additional, Webb, RC, additional, and Priviero, F, additional
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- 2024
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43. (054) Erectile Dysfunction in Young Adulthood as a Consequence of Early Childhood Obesity
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Rodrigues Dos Passos Junior, R, primary, Moura, K, additional, Vieira Dos Santos, C, additional, Townsend, P, additional, Wilson, E, additional, Torres Uchoa, E, additional, Mccarthy, C, additional, Wenceslau, C, additional, Ceravolo, G, additional, Webb, RC, additional, and Priviero, F, additional
- Published
- 2024
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44. On the physical meaning of the geometric factor and the effective thickness in the Montgomery method
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Oliveira, F. S., primary, Alves, L. M. S., additional, da Luz, M. S., additional, Romão, E. C., additional, and dos Santos, C. A. M., additional
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- 2024
- Full Text
- View/download PDF
45. Increased capture efficiency of Scolytinae with modified semi-funnel trap model
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Dos-Santos, C. A. A., primary, Trevisan, H., additional, De-Carvalho, A. G., additional, Plata-Rueda, A., additional, Zanuncio, J. C., additional, and De-Souza, T. S., additional
- Published
- 2024
- Full Text
- View/download PDF
46. Which influence does sarcopenic obesity have on the prognosis of patients with liver cirrhosis?
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Jacinto dos Santos, C., primary, Guerreiro, C. Sousa, additional, Sousa, J., additional, Cortez-Pinto, H., additional, and Vasques, J., additional
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- 2023
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47. Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections
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Heemskerk, M. T., Korbee, C. J., Esselink, J. J., dos Santos, C. Carvalho, van Veen, S., Gordijn, I. F., Vrieling, F., Walburg, K. V., Engele, C. G., Dijkman, K., Wilson, L., Verreck, F. A. W., Ottenhoff, T. H. M., and Haks, M. C.
- Published
- 2021
- Full Text
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48. Mesenchymal stem/stromal cell-based therapies for severe viral pneumonia: therapeutic potential and challenges
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Masterson, C. H., Ceccato, A., Artigas, A., dos Santos, C., Rocco, P. R., Rolandsson Enes, S., Weiss, D. J., McAuley, D., Matthay, M. A., English, K., Curley, G. F., and Laffey, J. G.
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- 2021
- Full Text
- View/download PDF
49. Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
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Matuozzo, D, Talouarn, E, Marchal, A, Zhang, P, Manry, J, Seeleuthner, Y, Zhang, Y, Bolze, A, Chaldebas, M, Milisavljevic, B, Gervais, A, Bastard, P, Asano, T, Bizien, L, Barzaghi, F, Abolhassani, H, Abou Tayoun, A, Aiuti, A, Alavi Darazam, I, Allende, L, Alonso-Arias, R, Arias, A, Aytekin, G, Bergman, P, Bondesan, S, Bryceson, Y, Bustos, I, Cabrera-Marante, O, Carcel, S, Carrera, P, Casari, G, Chaibi, K, Colobran, R, Condino-Neto, A, Covill, L, Delmonte, O, El Zein, L, Flores, C, Gregersen, P, Gut, M, Haerynck, F, Halwani, R, Hancerli, S, Hammarstrom, L, Hatipoglu, N, Karbuz, A, Keles, S, Kyheng, C, Leon-Lopez, R, Franco, J, Mansouri, D, Martinez-Picado, J, Metin Akcan, O, Migeotte, I, Morange, P, Morelle, G, Martin-Nalda, A, Novelli, G, Novelli, A, Palabiyik, F, Pan-Hammarstrom, Q, de Diego, R, Planas-Serra, L, Pleguezuelo, D, Prando, C, Pujol, A, Reyes, L, Riviere, J, Rodriguez-Gallego, C, Rojas, J, Rovere-Querini, P, Schluter, A, Shahrooei, M, Sobh, A, Soler-Palacin, P, 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Y., Lampropoulou V., Le Bourgeois F., Leo Y. -S., Leung D., Levin M., Levy M., Levy R., Li Z., Lilleri D., Lima E. J. A. B., Linglart A., Lopez-Collazo E., Lorenzo-Salazar J. M., Louapre C., Lubetzki C., Lung K. -C., Luyt C. -E., Lye D. C., Magnone C., Marchioni E., Marioli C., Marjani M., Marques L., Pereira J. M., Pueyo D. M., Marzana I., Mata-Martinez C., Mathian A., Matos L. R. B., Matthews G. V., Mayaux J., McLaughlin-Garcia R., Meersseman P., Mege J. -L., Mekontso-Dessap A., Melki I., Meloni F., Meritet J. -F., Merlani P., Akcan O. M., Mezidi M., Millereux M., Million M., Mirault T., Mircher C., Mirsaeidi M., Mizoguchi Y., Modi B. P., Mojoli F., Moncomble E., Melian A. M., Martinez A. M., Morandeira F., Mordacq C., Mouly S. J., Munoz-Barrera A., Nafati C., Nagashima S., Nakagama Y., Neven B., Neves J. F., Ng Y. -Y., Nielly H., Medina Y. N., Cuadros E. N., Ocejo-Vinyals J. G., Okamoto K., Oualha M., Ouedrani A., Ozcelik T., Ozkaya-Parlakay A., Pagani M., Papadaki M., Parola P., Pascreau T., Paul S., Paz-Artal E., Pedraza S., Pellecer N. C. G., Pellegrini S., Perez-Fernandez X. L., Philippe A., Philippot Q., Picod A., Piralla A., Ploin D., Poissy J., Poncelet G., Poulakou G., Pouletty M. S., Pourshahnazari P., Qiu-Chen J. L., Quentric P., Rambaud T., Raoult D., Raoult V., Rebillat A. -S., Redin C., Resmini L., Ricart P., Richard J. -C., Rigo-Bonnin R., rivet N., Rocamora-Blanch G., Rodero M. P., Rodrigo C., Rodriguez L. A., Rodriguez-Palmero A., Romero C. S., Rothenbuhler A., Roux D., Rovina N., Rozenberg F., Ruch Y., Ruiz M., del Prado M. Y. R., Ruiz-Rodriguez J. C., Sabater-Riera J., Saks K., Salagianni M., Sanchez O., Sanchez-Montalva A., Sanchez-Ramon S., Schidlowski L., Schmidt J., Schmidt M., Schuetz C., Schweitzer C. E., Scolari F., Seijo L., Seminario A. G., Seng P., Senoglu S., Seppanen M., Llovich A. S., Siguret V., Siouti E., Smadja D. 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N., Van Braeckel E., Bosteels C., Hoste L., Hoste E., Bauters F., De Clercq J., Heijmans C., Slabbynck H., Naesens L., Florkin B., Boulanger C., Vanderlinden D., Berkell M., Carelli V., Malhotra S., Mattiaccio A., Pippucci T., Seri M., Tacconelli E., van Agtmael M., Algera A. G., Appelman B., van Baarle F., Bax D., Beudel M., Bogaard H. J., Bomers M., Bonta P., Bos L., Botta M., de Brabander J., de Bree G., de Bruin S., Buis D. T. P., Bugiani M., Bulle E., Cloherty O. C. A., Dijkstra M., Dongelmans D. A., Dujardin R. W. G., Elbers P., Fleuren L., Geijtenbeek S. G. T., Girbes A., Goorhuis B., Grobusch M. P., Hafkamp F., Hagens L., Hamann J., Harris V., Hemke R., Heunks S. M. H. L., Hollmann M., Horn J., Hovius J. W., de Jong M. D., Koning R., Lim E. H. T., van Mourik N., Nellen J., Nossent E. J., Paulus F., Peters E., Pina-Fuentes D. A. I., van der Poll T., Preckel B., Prins J. M., Raasveld J., Reijnders T., de Rotte M. C. F. J., Schinkel M., Schultz M. J., Schrauwen F. A. 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U., Uzunhan Y., Vaittinadaayar P., Valent A., Valentian M., Valin N., Vallet H., Vaz M., Vazquezibarra M. -A., Vedie B., Velly L., Verstuyft C., Viallette C., Vicaut E., Vignes D., Vimpere D., Virlouvet M., Voiriot G., Voisot L., Weiss E., Weiss N., Winchenne A., Yordanov Y., Zafrani L., Zaidan M., Zaidi W., Zak C., Zarhrate-Ghoul A., Zatout O., Zeino S., Zeitouni M., Zemirli N., Zerah L., Zia O., Ziol M., Zolario O., Zuber J., Andrejak C., Angoulvant F., Bachelet D., Bartoli M., Basmaci R., Behilill S., Beluze M., Benkerrou D., Bhavsar K., Bouadma L., Bouchez S., Bouscambert M., Cervantes-Gonzalez M., Chair A., Coelho A., d'Ortenzio E., Debray M. -P., Deconinck L., Deplanque D., Descamps D., Desvallee M., Diallo A., Diouf A., Dorival C., Dubos F., Duval X., Elharrar B., Eloy P., Enouf V., Esperou H., Esposito-Farese M., Devouge E. F., Gault N., Gaymard A., Ghosn J., Gigante T., Gilg M., Guedj J., Hoctin A., Hoffmann I., Houas I., Hulot J. -S., Jaafoura S., Kaguelidou F., Kali S., Khalil A., Khan C., Laouenan C., Laribi S., Le M., Le Hingrat Q., Le Mestre S., Le Nagard H., Lescure F. -X., Levy Y., Lingas G., Lucet J. C., Malvy D., Mambert M., Meziane A., Mouquet H., Mullaert J., Neant N., Nguyen D., Noret M., Nseir S., Papadopoulos A., Paul C., Peiffer-Smadja N., Perpoint T., Petrov-Sanchez V., Peytavin G., Pham H., Picone O., Puechal O., Rabaud C., Rosa-Calatrava M., Rossignol B., Rossignol P., Roy C., Schneider M., Su R., Tardivon C., Tellier M. -C., Teoule F., Terrier O., Timsit J. -F., Tual C., Van Der Werf S., Vanel N., Veislinger A., Visseaux B., Wiedemann A., Yazdanpanah Y., Alavoine L., Behillil S., Burdet C., Charpentier C., Dechanet A., Ecobichon J. -L., Frezouls W., Houhou N., Lehacaut J., Letrou S., Lina B., Manchon P., Nouroudine M., Piquard V., Quintin C., Thy M., Vignali V., Chahine A., Waucquier N., Migaud M. -C., Djossou F., Mergeay-Fabre M., Lucarelli A., Demar M., Bruneau L., Gerardin P., Maillot A., Payet C., Laviolle B., Laine F., Paris C., Desille-Dugast M., Fouchard J., Pistone T., Perreau P., Gissot V., Goas C. L. E., Montagne S., Richard L., Chirouze C., Bouiller K., Desmarets M., Meunier A., Bourgeon M., Lefevre B., Jeulin H., Legrand K., Lomazzi S., Tardy B., Gagneux-Brunon A., Bertholon F., Botelho-Nevers E., Christelle K., Nicolas L., Roufai L., Amat K., Couffin-Cadiergues S., Hendou S., Foti G., Bellani G., Citerio G., Contro E., Pesci A., Valsecchi M. G., Cazzaniga M., Abad J., Accordino G., Achille C., Aguilera-Albesa S., Aguilo-Cucurull A., Ozkan E. A., Albisures J. A. R., Aldave J. C., Ramos M. A., Khan T. A., Aliberti A., Nadji S. A., Alkan G., AlKhater S. A., Allardet-Servent J., Alshahrani M. S., Alsina L., Amoura Z., Antoli A., Arrestier R., Aubart M., Auguet T., Avramenko I., Azot A., Bahram S., Bajolle F., Baldanti F., Baldolli A., Ballester M., Barrou B., Basso S., Bayhan G. I., Bezrodnik L., Bilbao A., Blanchard-Rohner G., Blanco I., Blandinieres A., Blazquez-Gamero D., Bloomfield M., Bolivar-Prados M., Borghesi A., Borie R., Botdhlo-Nevers E., Bousquet A., Boutolleau D., Bouvattier C., Boyarchuk O., Bravais J., Briones M. L., Brunner M. -E., Bruno R., Bueno M. R. P., Bukhari H., Bustamante J., Agra J. J. C., Capra R., Carapito R., Carrabba M., Casasnovas C., Caseris M., Cassaniti I., Castelle M., Castelli F., de Vera M. C., Castro M. V., Catherinot E., Celik J. B., Ceschi A., Chalumeau M., Charbit B., Cheng M. P., Clave P., Clotet B., Codina A., Comoli P., Corsico A. G., Sozeri B., Coskuner T., Cvetkovski A., Cyrus C., Dalmau D., Danion F., Darley D. R., Das V., Dauby N., Dauger S., De Munter P., de Pontual L., Dehban A., Delplancq G., Desguerre I., Di Sabatino A., Diehl J. -L., Dobbelaere S., Dominguez-Garrido E., Dubost C., Ekwall O., Bozdemir S. E., Elnagdy M. H., Emiroglu M., Endo A., Erdeniz E. H., Aytekin S. E., Lasa M. P. 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P., Schuurmans A., Schuurmans J., Sigaloff K., Slim M. A., Smeele P., Smit M., Stijnis C. S., Stilma W., Teunissen C., Thoral P., Tsonas A. M., Tuinman P. R., van der Valk M., Veelo D., Volleman C., de Vries H., Vught L. A., van Vugt M., Wouters D., Zwinderman A. H., Brouwer M. C., Wiersinga W. J., Vlaar A. P. J., Tompkins M. F., Alba C., Hupalo D. N., Rosenberger J., Sukumar G., Wilkerson M. D., Zhang X., Lack J., Oler A. J., Dobbs K., Danielson J. J., Biondi A., Bettini L. R., D'Angio' M., Beretta I., Imberti L., Sottini A., Quaresima V., Quiros-Roldan E., Rossi C., Meyts I., Zhang S. -Y., Puel A., Notarangelo L. D., Boisson-Dupuis S., Su H. C., Boisson B., Jouanguy E., Zhang Q., Abel L., and Cobat A.
- Abstract
Background: We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15–20% of cases of life-threatening COVID-19 in unvaccinated patients. Therefore, the determinants of life-threatening COVID-19 remain to be identified in ~ 80% of cases. Methods: We report here a genome-wide rare variant burden association analysis in 3269 unvaccinated patients with life-threatening COVID-19, and 1373 unvaccinated SARS-CoV-2-infected individuals without pneumonia. Among the 928 patients tested for autoantibodies against type I IFN, a quarter (234) were positive and were excluded. Results: No gene reached genome-wide significance. Under a recessive model, the most significant gene with at-risk variants was TLR7, with an OR of 27.68 (95%CI 1.5–528.7, P = 1.1 × 10−4) for biochemically loss-of-function (bLOF) variants. We replicated the enrichment in rare predicted LOF (pLOF) variants at 13 influenza susceptibility loci involved in TLR3-dependent type I IFN immunity (OR = 3.70[95%CI 1.3–8.2], P = 2.1 × 10−4). This enrichment was further strengthened by (1) adding the recently reported TYK2 and TLR7 COVID-19 loci, particularly under a recessive model (OR = 19.65[95%CI 2.1–2635.4], P = 3.4 × 10−3), and (2) considering as pLOF branchpoint variants with potentially strong impacts on splicing among the 15 loci (OR = 4.40[9%CI 2.3–8.4], P = 7.7 × 10−8). Finally, the patients with pLOF/bLOF variants at these 15 loci were significantly younger (mean age [SD] = 43.3 [20.3] years) than the other patients (56.0 [17.3] years; P = 1.68 × 10−5). Conclusions: Rare variants of TLR3- and TLR7-dependent type I IFN immunity genes can underlie life-threatening COVID-19, particularly with recessive inheritance, in patients under 60 years old.
- Published
- 2023
50. EP-376 - DO BISTURI AO ALGORITMO: O INSTITUTO ADOLFO LUTZ REINVENTA A PATOLOGIA
- Author
-
Takahashi, Carlos Pires F. Jr, Takahashi, Juliana Possatto F., de Lacerda, Paulo Sergio Padua, Borges, Cinthya dos Santos C., Ferreira, Camila Santos da Silva, Guerra, Juliana Mariotti, and de Araujo, Leonardo José Tadeu
- Published
- 2024
- Full Text
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