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1. Hand, foot, and mouth disease: could EPs® 7630 be a treatment option? A prospective randomized open-label multicenter clinical study

Author

Murat Sütçü, Manolya Kara, Funda Yıldız, Ömer Kılıç, Tugce Tural Kara, Gulsen Akkoc, Ayşe Büyükçam, Şefika Elmas Bozdemir, Özlem Özgür Gündeşlioğlu, Doruk Gül, Merve İseri Nepesov, and Ateş Kara

Subjects
hand, foot, mouth disease, EPs® 7630, children, herbal remedy, Pediatrics, RJ1-570
Abstract

PurposeHand, foot and mouth disease (HFMD) is a viral contagious disease of children caused by human enteroviruses (EVs) and coxsackieviruses (CVs). There is no specific treatment option for HFMD. EPs® 7630's anti-infective and immunomodulatory properties have previously been demonstrated in several in vitro and in vivo studies; however, the use of this herbal medicine in children with HFMD has not previously been investigated.MethodsThis prospective randomized multicenter clinical study included 208 children with HFMD. The diagnosis was made by pediatricians. The patients who were within the first 48 h of symptom onset (according to the first onset of fever and skin findings) were enrolled. The study participants were assigned into 2 groups as EPs® 7630 and control groups. All patients were followed up twice more, 48 h after the first admission and on the 5th–7th day. Another phone evaluation was conducted for those with continued complaints from the previous visit.ResultsThe median age was 27 (12–112) months. The male-female ratio was 0.98. One hundred thirty one (63%) of 190 patients had no history of household contact. EPs® 7630 group included 94 and control group included 96 patients. A significant difference was found between the groups in terms of complaint scores at the visits made at the 48th h of the treatment and on days 5–7 (p

Published
2024
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2. Measuring and Evaluating the Adherence to and Effectiveness of Formula Milk Use in Healthy Infants in Türkiye

Author

Fatih ÖZDENER, İlknur KILIÇ, Coşkun SAF, Tuğba DEMİRCAN BİLEN, Dicle ÇELİK, Nurdan URAŞ, Doruk GÜL, Gamze DEMİREL, Hayrettin TEMEL, Dilek ÇOBAN, ENVER MAHIR GÜLCAN, Alihan SÜRSAL, Vildan ERTEKİN, and Mukadder Ayşe SELİMOĞLU

Subjects
formula milk, adherence, nutritional deficiency, growth, Medicine (General), R5-920
Abstract

Objective: Formula milk aims to mimic breast milk or can serve as a complementary diet, thus reducing the risk of developing nutritional deficiencies. In this study, we evaluated the factors affecting compliance with the use of prebiotic formula milk with a galacto-oligosaccharides/fructo-oligosaccharides ratio of 9: 1. Methods: The study included 63 healthy girls and 58 healthy boys who consumed formula milk for 4-12 months. A brief survey was conducted among the parents of these children at the end of the first and third months. Height, weight for age, and weight for height z-scores were compared between the first and follow-up visits. Perceived symptoms, frequency of infections, complementary food intake, and frequency of stool movements were also discussed. Results: The anthropometrics significantly increased over the three months. Intolerability negatively affected compliance with formula use (p

Published
2023
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3. SARS-CoV-2 seropositivity among pediatric health care personnel after the first peak of the pandemic: nationwide surveillance in Turkey

Author

Pembe Derin Oygar, Ayşe Büyükçam, Zümrüt Şahbudak Bal, Nazan Dalgıç, Şefika Elmas Bozdemir, Adem Karbuz, Benhur Şirvan Çetin, Yalçın Kara, Ceren Çetin, Nevin Hatipoğlu, Hatice Uygun, Fatma Deniz Aygün, Selda Hançerli Törün, Dicle Şener Okur, Dilek Yılmaz Çiftdoğan, Tuğçe Tural Kara, Aysun Yahşi, Arife Özer, Sevliya Öcal Demir, Gülşen Akkoç, Cansu Turan, Enes Salı, Semra Şen, Emine Hafize Erdeniz, Soner Sertan Kara, Melike Emiroğlu, Tuğba Erat, Hacer Aktürk, Sibel Laçinel Gürlevik, Murat Sütçü, Zeynep Gökçe Gayretli Aydın, Başak Yıldız Atikan, Edanur Yeşil, Gizem Güner, Emel Çelebi, Kadir Efe, Didem Kızmaz İşançlı, Habibe Selver Durmuş, Seher Tekeli, Ayşe Karaaslan, Lida Bülbül, Habip Almış, Özge Kaba, Yıldız Ekemen Keleş, Bahadır Yazıcıoğlu, Şerife Bahtiyar Oğuz, Hüsnü Fahri Ovalı, Hazal Helin Doğan, Solmaz Çelebi, Deniz Çakır, Burcugül Karasulu, Gülsüm Alkan, İrem Yenidoğan, Doruk Gül, Burcu Parıltan Küçükalioğlu, Gülhadiye Avcu, Musa Gürel Kukul, Melis Bilen, Belma Yaşar, Tuğba Üstün, Ömer Kılıç, Yasemin Akın, Sinem Oral Cebeci, Ibrahim Hakan Bucak, Mehpare Sarı Yanartaş, Aslıhan Şahin, Sertaç Arslanoğlu, Murat Elevli, Rabia Çoban, Şadiye Kübra Tüter Öz, Halil Hatipoğlu, İlyas Tolga Erkum, Mehmet Turgut, Asuman Demirbuğa, Taha Özçelik, Diclehan Çiftçi, Emine Ergül Sarı, Gökhan Akkuş, Sadık Sami Hatipoğlu, Ener Çağrı Dinleyici, Mustafa Hacımustafaoğlu, Ferda Özkınay, Zafer Kurugöl, Ali Bülent Cengiz, Ayper Somer, Hasan Tezer, and Ateş Kara

Subjects
SARS-CoV-2, health care personnel, serology, COVID-19, personnel protective equipment use, Infectious and parasitic diseases, RC109-216
Abstract

Background: Understanding SARS-CoV-2 seroprevalence among health care personnel is important to explore risk factors for transmission, develop elimination strategies and form a view on the necessity and frequency of surveillance in the future. Methods: We enrolled 4927 health care personnel working in pediatric units at 32 hospitals from 7 different regions of Turkey in a study to determine SARS Co-V-2 seroprevalence after the first peak of the COVID-19 pandemic. A point of care serologic lateral flow rapid test kit for immunoglobulin (Ig)M/IgG was used. Seroprevalence and its association with demographic characteristics and possible risk factors were analyzed. Results: SARS-CoV-2 seropositivity prevalence in health care personnel tested was 6.1%. Seropositivity was more common among those who did not universally wear protective masks (10.6% vs 6.1%). Having a COVID-19-positive co-worker increased the likelihood of infection. The least and the most experienced personnel were more likely to be infected. Most of the seropositive health care personnel (68.0%) did not suspect that they had previously had COVID-19. Conclusions: Health surveillance for health care personnel involving routine point-of-care nucleic acid testing and monitoring personal protective equipment adherence are suggested as important strategies to protect health care personnel from COVID-19 and reduce nosocomial SARS-CoV-2 transmission.

Published
2021
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4. Evaluation of vaccination status of health care workers for recommended vaccines and their acceptance of SARS-CoV-2 vaccines

Author

Pembe Derin Oygar, Ayşe Büyükçam, Zumrut Sahbudak Bal, Nazan Dalgıç, Şefika Elmas Bozdemir, Adem Karbuz, Benhur Şirvan Çetin, Yalçın Kara, Ceren Çetin, Nevin Hatipoğlu, Hatice Uygun, Fatma Deniz Aygün, Selda Hançerli Törün, Dicle Şener Okur, Dilek Yılmaz Çiftdoğan, Tuğçe Tural Kara, Aysun Yahşi, Arife Özer, Sevliya Öcal Demir, Gülşen Akkoç, Cansu Turan, Enes Salı, Semra Şen, Emine Hafize Erdeniz, Soner Sertan Kara, Melike Emiroğlu, Tuğba Erat, Hacer Aktürk, Sibel Laçinel Gürlevik, Murat Sütçü, Zeynep Gökçe Gayretli Aydın, Başak Yıldız Atikan, Edanur Yeşil, Gizem Güner Özenen, Emel Çelebi, Kadir Efe, Didem Kizmaz isancli, Habibe Selver Durmuş, Seher Tekeli, Ayşe Karaaslan, Lida Bülbül, Habip Almış, Özge Kaba, Yıldız Ekemen Keleş, Bahadır Yazıcıoğlu, Serife Bahtiyar Oğuz, Hüsnü Fahri Ovalı, Hazal Helin Doğan, Solmaz Çelebi, Deniz Çakir, Burcugül Karasulu, Gülsüm Alkan, İrem Yenidoğan, Doruk Gül, Burcu Parıltan Kücükalioğlu, Gülhadiye Avcu, Musa Gürel Kukul, Melis Bilen, Belma Yaşar, Tuğba Üstün, Ömer Kılıç, Yasemin Akın, Sinem Oral Cebeci, İbrahim Hakan Bucak, Mehpare Sarı Yanartaş, Aslıhan Şahin, Sertaç Arslanoglu, Murat Elevli, Rabia Çoban, Sadiye Kübra Tuter Öz, Halil Hatipoğlu, İlyas Tolga Erkum, Mehmet Turgut, Asuman Demirbuğa, Taha Özçelik, Diclehan Çiftçi, Emine Ergül Sarı, Gökhan Akkuş, Sadık Sami Hatipoğlu, Ener Cağrı Dinleyici, Mustafa Hacimustafaoğlu, Ferda Özkınay, Zafer Kurugöl, Ali Bulent Cengiz, Ayper Somer, Hasan Tezer, and Ateş Kara

Subjects
health care workers, vaccination, measles, influenza, sars-cov-2, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950
Abstract

Introduction Health care workers (HCWs) are disproportionately exposed to infectious diseases and play a role in nosocomial transmission, making them a key demographic for vaccination. HCW vaccination rates are not optimal in many countries; hence, compulsory vaccination policies have been implemented in some countries. Although these policies are effective and necessary under certain conditions, resolving HCWs’ hesitancies and misconceptions about vaccines is crucial. HCWs have the advantage of direct contact with patients; hence, they can respond to safety concerns, explain the benefits of vaccination, and counter antivaccine campaigns that escalate during pandemics, as has been observed with COVID-19. Method A short survey was carried out in May–June 2020 on the vaccination status of HCWs working with pediatric patients with COVID-19. The survey inquired about their vaccination status (mumps/measles/rubella [MMR], varicella, influenza, and diphtheria/tetanus [dT]) and willingness to receive hypothetical future COVID-19 vaccines. The respondents were grouped according to gender, age, occupation, and region. Results In total, 4927 HCWs responded to the survey. Most were young, healthy adults. The overall vaccination rates were 57.8% for dT in the past 10 years, 44.5% for MMR, 33.2% for varicella, and 13.5% for influenza. Vaccination rates were the highest among physicians. The majority of HCWs (81%) stated that they would be willing to receive COVID-19 vaccines. Conclusion Although vaccination rates for well-established vaccines were low, a majority of HCWs were willing to receive COVID-19 vaccines when available. Education and administrative trust should be enhanced to increase vaccination rates among HCWs.

Published
2022
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5. Students' Ability to Determine the Truth Value of Mathematical Propositions in the Context of Operation Meanings

Author

Doruk, Muhammet and Doruk, Gül

Abstract

The aim of this study was to reveal 5th class middle school students' determination skills on the truth value of mathematical propositions about multiplication and division. These skills were evaluated in the context of operation meanings preferred and arguments constructed by the students in the process. The research group consisted of 95 fifth-grade students studying at a state middle school in Turkey. The study an example of sequential explanatory from mixed research designs. The data of the study were collected in three stages. In the first and the second stage, quantitative data of the study were gathered with Awareness Questionnaire (AQ) and Proposition Evaluation Test (PET) developed by the researchers. In the third stage, semi-structured task-based interviews were conducted. As a result of the study, it was revealed that students had more difficulty in selecting false mathematical propositions. Most of the students used counterexample and deductive warrants for the falsity of the propositions, and inductive warrants for the truth of the propositions. These results showed that determining the false propositions was an important ability and students preferring operational meanings had disadvantages in this process.

Published
2022
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6. SARS-CoV-2 seropositivity among pediatric health care personnel after the first peak of the pandemic: nationwide surveillance in Turkey

Author

Halil Hatipoğlu, Nevin Hatipoğlu, İrem Yenidoğan, Aslıhan Şahin, Ayşe Büyükcam, Gizem Guner, Gülhadiye Avcu, Burcu Parıltan Küçükalioğlu, Murat Sütçü, Dicle Şener Okur, Yalçın Kara, Gökhan Akkuş, Sinem Oral Cebeci, Başak Yıldız Atikan, Ferda Ozkinay, Mustafa Hacimustafaoglu, Melike Emiroglu, Deniz Çakır, Zafer Kurugöl, Tuğçe Tural Kara, Seher Tekeli, Yasemin Akın, Ceren Çetin, Ayşe Karaaslan, Adem Karbuz, Emine Hafize Erdeniz, Gülsüm Alkan, Aysun Yahşi, Hazal Helin Doğan, Şerife Bahtiyar Oğuz, Bahadir Yazicioglu, Soner Sertan Kara, Rabia Çoban, Doruk Gül, Arife Özer, Musa Gürel Kukul, Hacer Aktürk, Asuman Demirbuğa, Hatice Uygun, Hüsnü Fahri Ovalı, Sibel Laçinel Gürlevik, Taha Özçelik, Habip Almiş, Habibe Selver Durmuş, Zümrüt Şahbudak Bal, Belma Yaşar, Ener Cagri Dinleyici, Zeynep Gökçe Gayretli Aydın, Sevliya Öcal Demir, Pembe Derin Oygar, Nazan Dalgic, Emel Çelebi, Sadık Sami Hatipoğlu, Tuğba Erat, İlyas Tolga Erkum, Ibrahim Hakan Bucak, Dilek Yılmaz Çiftdoğan, Mehmet Turgut, Didem Kizmaz Işançli, Benhur Şirvan Çetin, Hasan Tezer, Semra Şen, Sertac Arslanoglu, Tuğba Üstün, Omer Kilic, Edanur Yeşil, Ali Bülent Cengiz, Enes Sali, Sefika Elmas Bozdemir, Murat Elevli, Diclehan Çiftçi, Gülşen Akkoç, Ayper Somer, Yıldız Ekemen Keleş, Mehpare Sarı Yanartaş, Selda Hançerli Törün, Kadir Efe, Ateş Kara, Sadiye Kubra Tuter Oz, Cansu Turan, Özge Kaba, Melis Bilen, Solmaz Celebi, Emine Ergül Sarı, Lida Bülbül, Fatma Deniz Aygün, Burcugül Karasulu, İstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Murat Sütçü / 0000-0002-2078-9796, Halil Uğur Hatipoğlu / 0000-0002-7393-677X, Doruk Gül / 0000-0003-2558-3719, Sütçü, Murat, Gül, Doruk, Hatipoğlu, Halil Uğur, Murat Sütçü / ABG-7336-2021, Doruk Gül / AGJ-2448-2022, Halil Uğur Hatipoğlu / AAR-7056-2020, Murat Sütçü / 55499199300, Doruk Gül / 57222108765, Halil Uğur Hatipoğlu / 56545443800, Aktürk, Hacer, Yenidoğan, İrem, Oygar, P.D., Büyükçam, A., Bal, Z.S., Dalgıç, N., Bozdemir, S.E., Karbuz, A., Çetin, B.S., Kara, Y., Çetin, C., Hatipoğlu, N., Uygun, H., Aygün, F.D., Torun, S.H., Okur, D.S., Çiftdoğan, D.Y., Kara, T.T., Yahşi, A., Özer, A., Demir, S.O., Akkoç, G., Turan, C., Salı, E., Şen, S., Erdeniz, E.H., Kara, S.S., Emiroğlu, M., Erat, T., Gürlevik, S.L., Sütçü, M., Aydın, Z.G.G., Atıkan, B.Y., Yeşil, E., Güner, G., Çelebi, E., Efe, K., İsançlı, D.K., Durmuş, H.S., Tekeli, S., Karaaslan, A., Bülbül, L., Almış, H., Kaba, O., Keleş, Y.E., Yazıcıoğlu, B., Oğuz, S.B., Ovalı, H.F., Doğan, H.H., Çelebi, S., Çakır, D., Karasulu, B., Alkan, G., Gül, D., Küçükalioğlu, B.P., Avcu, G., Kukul, M.G., Bilen, M., Yaşar, B., Üstün, T., Kılıç, O., Akın, Y., Cebeci, S.O., Buçak, I.H., Yanartaş, M.S., Şahin, A., Arslanoğlu, S., Elevli, M., Çoban, R., Öz, S.K.T., Hatipoğlu, H., Erkum, I.T., Turgut, M., Demirbuğa, A., Özçelik, T., Çiftci, D., Sarı E.E., Akkuş, G., Hatipoğlu, S.S., Dinleyici, E.Ç., Hacımustafaoğlu, M., Özkınay, F., Kurugöl, Z., Cengiz, A.B., Somer, A., Tezer, H., Kara, A., Koç University Hospital, and School of Medicine

Subjects
Microbiology (medical), personnel protective equipment use, Coronavirus disease 2019 (COVID-19), health care personnel, Transmission (medicine), business.industry, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), serology, COVID-19, General Medicine, Infectious and parasitic diseases, RC109-216, Infectious Diseases, Environmental health, Pandemic, Health care, Seroprevalence, Medicine, Infectious diseases, business, Personal protective equipment, Health care personnel, Serology, Personnel protective equipment use, Point of care
Abstract

Background: understanding SARS-CoV-2 seroprevalence among health care personnel is important to ex-plore risk factors for transmission, develop elimination strategies and form a view on the necessity and frequency of surveillance in the future. Methods: we enrolled 4927 health care personnel working in pediatric units at 32 hospitals from 7 different regions of Turkey in a study to determine SARS Co-V-2 seroprevalence after the first peak of the COVID-19 pandemic. A point of care serologic lateral flow rapid test kit for immunoglobulin (Ig)M/IgG was used. Seroprevalence and its association with demographic characteristics and possible risk factors were analyzed. Results: SARS-CoV-2 seropositivity prevalence in health care personnel tested was 6.1%. Seropositivity was more common among those who did not universally wear protective masks (10.6% vs 6.1%). Having a COVID-19-positive co-worker increased the likelihood of infection. The least and the most experienced personnel were more likely to be infected. Most of the seropositive health care personnel (68.0%) did not suspect that they had previously had COVID-19. Conclusions: health surveillance for health care personnel involving routine point-of-care nucleic acid testing and monitoring personal protective equipment adherence are suggested as important strategies to protect health care personnel from COVID-19 and reduce nosocomial SARS-CoV-2 transmission., NA

Published
2021

7. COVID-19 Pandemisinde Enfeksiyon Kontrol Çalışmaları Çerçevesinde Çocuk Hastalarla Çalışan Sağlık Personeli Eğitimi

Author

Kadir Efe, Nazan Dalgic, Sadık Sami Hatipoğlu, Mehmet Turgut, İlyas Tolga Erkum, Zümrüt Şahbudak Bal, Hasan Tezer, Lida Bülbül, Tuğba Erat, Deniz Çakır, Zafer Kurugöl, Gizem Guner, Cansu Turan, Ayşe Büyükcam, Gülhadiye Avcu, Özge Kaba, Nevin Hatipoğlu, Habip Almiş, Asuman Demirbuğa, Burcu Parıltan Küçükalioğlu, Murat Sütçü, Yalçın Kara, Ateş Kara, Murat Elevli, Ayşe Karaarslan, Pembe Derin Oygar, Hazal Helin Doğan, Sadiye Kubra Tuter Oz, Gülşen Akkoç, Melike Emiroglu, Selda Hançerli Törün, Musa Gürel Kukul, Dicle Şener Okur, Ibrahim Hakan Bucak, Tuğçe Tural Kara, Mustafa Hacimustafaoglu, Adem Karbuz, Didem Kizmaz Işançli, Ali Bülent Cengiz, Enes Sali, Emine Hafize Erdeniz, Gülsüm Alkan, Sibel Laçinel Gürlevik, Emine Ergül Sarı, Ceren Çetin, Seher Tekeli, Melis Bilen, Sefika Elmas Bozdemir, Ener Cagri Dinleyici, İrem Yenidoğan, Başak Yıldız Atikan, Soner Sertan Kara, Arife Özer, Belma Yaşar, Fatma Deniz Aygün, Ayper Somer, Halil Hatipoğlu, Tuğba Üstün, Omer Kilic, Dilek Yılmaz Çiftdoğan, Hatice Uygun, Benhur Şirvan Çetin, Yasemin Akın, Gökhan Akkuş, Semra Şen, Doruk Gül, Solmaz Celebi, Sinem Oral Cebeci, Edanur Yeşil, Sertac Arslanoglu, Aysun Yahşi, Aslıhan Şahin, Burcugül Karasulu, Şerife Bahtiyar Oğuz, Habibe Selver Durmuş, Sevliya Öcal Demir, Hacer Aktürk, Taha Özçelik, Ferda Ozkinay, Bahadir Yazicioglu, Zeynep Gökçe Gayretli Aydın, Hüsnü Fahri Ovalı, Emel Çelebi, Yıldız Ekemen Keleş, and Mehpare Sarı Yanartaş

Subjects
Infectious Diseases, Coronavirus disease 2019 (COVID-19), Pediatrics, Perinatology and Child Health
Abstract

Objective: In the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic caused by SARS-CoV-2, proved to be no exception. Many healthcare workers died in the early stages of pandemic due to inadequate precautions and insufficient protection. It is essential to protect and maintain the safety of healthcare personnel for the confinement of pandemic as well as continuity of qualified healthcare services which is already under strain. Educating healthcare personnel on appropiate use of personal protective equipment (PPE) is as essential as procuring them. Material and Methods: A survey is conducted on 4927 healthcare personnel working solely with pediatric patients from 32 different centers. Education given on PPE usage were questioned and analyzed depending on age, sex, occupation and region. Results: Among four thousand nine hundred twelve healthcare personnel from 32 different centers 91% (n= 4457) received education on PPE usage. Of those who received education only 36% was given both theoretical and applied education. Although there was no differences among different occupation groups, receiving education depended on regions. Conclusion: It is essential to educate healthcare personnel appropiately nationwidely for the continuity of qualified healthcare services during the pandemic.

Published
2020
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8. Education of Healthcare Personnel Working with Pediatric Patients During COVID-19 Pandemic within the Framework of Infection Control

Author

Gülsüm Alkan, Deniz Çakır, Zafer Kurugöl, Hacer Aktürk, Bahadir Yazicioglu, Mehmet Turgut, Hasan Tezer, Soner Sertan Kara, Tuğçe Tural Kara, Zeynep Gökçe Gayretli Aydın, Kadir Efe, Fatma Deniz Aygün, Adem Karbuz, Yasemin Akın, Didem Kizmaz Işançli, Emine Hafize Erdeniz, Hatice Uygun, Sertac Arslanoglu, Habibe Selver Durmuş, Melike Emiroglu, Hazal Helin Doğan, Yıldız Ekemen Keleş, Özge Kaba, Ener Cagri Dinleyici, Burcugül Karasulu, Mehpare Sarı Yanartaş, Mustafa Hacimustafaoglu, Tuğba Üstün, Omer Kilic, Dilek Yılmaz Çiftdoğan, Dicle Şener Okur, Gülşen Akkoç, Murat Elevli, Semra Şen, Ateş Kara, Sadiye Kubra Tuter Oz, Selda Hançerli Törün, Hüsnü Fahri Ovalı, Benhur Şirvan Çetin, Musa Gürel Kukul, Lida Bülbül, Ayper Somer, Edanur Yeşil, İrem Yenidoğan, Emel Çelebi, Burcu Parıltan Küçükalioğlu, Murat Sütçü, Nevin Hatipoğlu, Ayşe Büyükcam, Gülhadiye Avcu, Aysun Yahşi, Zümrüt Şahbudak Bal, Sinem Oral Cebeci, Sevliya Öcal Demir, Pembe Derin Oygar, Şerife Bahtiyar Oğuz, Halil Hatipoğlu, Aslıhan Şahin, Emine Ergül Sarı, Tuğba Erat, Ferda Ozkinay, Habip Almiş, Başak Yıldız Atikan, Gökhan Akkuş, Ali Bülent Cengiz, Enes Sali, Sefika Elmas Bozdemir, Asuman Demirbuğa, Ceren Çetin, Doruk Gül, Yalçın Kara, Taha Özçelik, Seher Tekeli, Solmaz Celebi, Ayşe Karaarslan, Nazan Dalgic, Sadık Sami Hatipoğlu, İlyas Tolga Erkum, Sibel Laçinel Gürlevik, Melis Bilen, Belma Yaşar, Cansu Turan, Arife Özer, and Gizem Guner

Subjects
Infectious Diseases, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pediatrics, Perinatology and Child Health, Health care, Pandemic, Medicine, Infection control, Medical emergency, business, medicine.disease, Personal protective equipment
Abstract

Objective: In the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic caused by SARS-CoV-2, proved to be no exception. Many healthcare workers died in the early stages of pandemic due to inadequate precautions and insufficient protection. It is essential to protect and maintain the safety of healthcare personnel for the confinement of pandemic as well as continuity of qualified healthcare services which is already under strain. Educating healthcare personnel on appropiate use of personal protective equipment (PPE) is as essential as procuring them. Material and Methods: A survey is conducted on 4927 healthcare personnel working solely with pediatric patients from 32 different centers. Education given on PPE usage were questioned and analyzed depending on age, sex, occupation and region. Results: Among four thousand nine hundred twelve healthcare personnel from 32 different centers 91% (n= 4457) received education on PPE usage. Of those who received education only 36% was given both theoretical and applied education. Although there was no differences among different occupation groups, receiving education depended on regions. Conclusion: It is essential to educate healthcare personnel appropiately nationwidely for the continuity of qualified healthcare services during the pandemic.

Published
2020
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10. Çocuklarda A’dan Z’ye Beslenme

Author

Gürkan Atay, Pınar Karadeniz, Muhammet Bulut, Doruk Gül, Osman Yeşilbaş, Kahraman Yakut, Aslı Kibris, Murat Sütçü, Nevzat Aykut Bayrak, Didem Arman, Raziye Dut, Eda Sunnetci Silistre, Başak Adaklı Aksoy, Nursu Kara, Evrim Şenkal, Gamze Özgürhan, Ozan Ozkaya, Senem Ayça, Aysenur Kaya, Yasemin Soylu, Alper Alnak, Muhammet Ali Varkal, Nafiye Emel Çakar, Banu Bal Çermik, Onur Bağcı, Güzide Doğan, Handan Ayhan Akoğlu, Nurdan Uras, Sacit Yıldız, Canan Yolcu, Hulya Nalcacioglu, Nezir Özgün, Bağdagül Aksu, Rumeysa Bektaş, Gökten Öngel, Burcu Ece Kök Özyürek, Burcu Volkan, İsmail Gönen, Zumrut Kocabey Sutcu, Mahya Sultan Tosun, Hasret Ayyıldız Civan, Ferit Durankuş, Pınar Arıcan, Halil Ugur Hatipoglu, Pınar Yılmazbaş, and Yasemin Eraslan

Subjects
Gynecology, medicine.medical_specialty, business.industry, Medicine, business
Abstract

Beslenme, anne karnindan baslayarak bireyin yasam boyu sagliginin korunmasi, gelistirilmesi ve yasam kalitesinde en onemli faktorlerden biridir. Ozellikle cocukluk caginda kazanilan saglikli, yeterli ve dengeli beslenme aliskanliginin yasamin programlanmasindaki rolu net olarak anlasilmistir. Ayrica, kronik hastaligi olan cocuklarda hastaliga ozgu dogru beslenme morbidite ve mortaliteyi azaltmakta , hatta bazi kronik hastaliklarda beslenme, tedavinin onemli bir parcasini olusturmaktadir.Eriskin sagligi icin anahtar rol oynayan cocukluk donemi beslenmesi ve kronik hastaligi olan cocuklarin beslenmesinin duzenlenmesinde aile hekimleri ve cocuk sagligi hekimleri onemli bir gorev ustlenmektedir. Bu kitabin amaci, saglikli ve kronik hastaligi olan cocuklarin beslenmesi ile konulari, pratikte sik karsilastiklari sorunlari ve cozumlerini sade ve anlasilir bir sekilde sunmaktir. Bu amacimizdaki basari bizim icin en buyuk mutluluk olacaktir.Kitabin hazirlanmasinda degerli zamanlarini ayirarak katkida bulunan tum yazarlara ve kitabin basimina kadar olan surec icinde katkilari nedeniyle Akademisyen Yayinevi’ne tesekkur ederiz.

Published
2020
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12. Rhabdomyolysis after BNT162b2 mRNA Covid-19 vaccine in an adolescent male

Author

Murat, Sutcu, Doruk, Gul, Fatih, Atik, Manolya, Kara, İstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Murat Sütçü / 0000-0002-2078-9796, Doruk Gül / 0000-0003-2558-3719, Fatih Atik / 0000-0003-4435-556X, Manolya Kara / 0000-0001-6234-7024, Sütçü, Murat, Gül, Doruk, Atik, Fatih, Kara, Emine Manolya, Murat Sütçü / ABG-7336-2021, Doruk Gül / AGJ-2448-2022, Fatih Atik / FXI-4226-2022, Manolya Kara / CXW-4939-2022, Murat Sütçü / 55499199300, Doruk Gül / 57222108765, Fatih Atik / 57789999700, and Manolya Kara / 57213122996

Subjects
Male, Myocarditis, COVID-19 Vaccines, Treatment Outcome, Adolescent, COVID-19, Humans, General Medicine, Pfizer-BioNTech COVID-19, BNT162 Vaccine, Rhabdomyolysis, Pfizer-BioNTech COVID-19, rhabdomyolysis, adolescent
Abstract

Pfizer-BioNTech COVID-19 (BNT162b2) conferred a high level of protection against Covid-19 with a proven short-term safety profile. Although cases of vaccine-associated myopericarditis have been reported, the existence of rhabdomyolysis without myocarditis has not yet been published. A 16-year-old, healthy male patient, who did not use any herbal or illegal drugs before, was admitted with muscle pain that developed after the second dose of BNT162b2 vaccine. Cardiac examination and heart enzymes were normal and the patient had significantly higher creatinine kinase levels. The patient, whose enzymes returned to normal with only force hydration therapy, recovered without complications. Reporting the side effects of the vaccine, which has a short history of application to large populations, is of vital importance in the conduct of vaccine development studies and in identifying the risky group in terms of side effects. © 2022 The College of Medicine and the Medical Association of Malawi. 2-s2.0-85133663932 WOS:000863008400013 Q4

Published
2022
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13. Multisystem inflammatory syndrome in children associated with COVID-19 in 101 cases from Turkey (Turk-MISC study)

Author

Dilek Yilmaz Ciftdogan, Yildiz Ekemen Keles, Adem Karbuz, Benhur Sirvan Cetin, Sefika Elmas Bozdemir, Eda Kepenekli Kadayifci, Ozge Metin Akcan, Arife Ozer, Tugba Erat, Murat Sutcu, Ayse Buyukcam, Nursen Belet, Emine Hafize Erdeniz, Nazan Dalgic Karabulut, Selda Hancerli Torun, Selim Oncel, Zerrin Orbak, Ozden Turel, Zeynep Gokce Gayretli Aydin, Omer Kilic, Aysun Yahsi, Ahu Kara Aksay, Zeynep Ergenc, Mey Talip Petmezci, Mehmet Burhan Oflaz, Remzi Sarikaya, Gülcin Otar Yener, Seval Ozen, Doruk Gul, Gazi Arslan, Soner Sertan Kara, Demet Demirkol, Pinar Yazici Ozkaya, Yilmaz Yozgat, Celal Varan, Manolya Kara, Gul Arga, Nurhayat Yakut, Ahmet Osman Kilic, Ozlem Cakici, Mehmet Kucuk, Ozge Kaba, Hatice Karaoglu Asrak, Burcu Bursal Duramaz, Tahir Dalkiran, Ayse Berna Anil, Mehmet Turgut, Bulent Karapinar, Ayper Somer, Ferhan Elmali, Ener Cagri Dinleyici, Ergin Ciftci, Ates Kara, İstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Murat Sütçü / 0000-0002-2078-9796, Doruk Gül / 0000-0003-2558-3719, Sütçü, Murat, Gül, Doruk, Murat Sütçü / ABG-7336-2021, Doruk Gül / AGJ-2448-2022, Murat Sütçü / 55499199300, Doruk Gül / 57222108765, Yilmaz Ciftdogan D., Ekemen Keles Y., Karbuz A., ÇETİN B. Ş., Elmas Bozdemir S., KEPENEKLİ KADAYİFCİ E., Metin Akcan O., Ozer A., Erat T., Sutcu M., et al., TÜREL, Özden, and {{contributorinst}}

Subjects
Male, Sars, Turkey, MIS-C, shock, Mucocutaneous Lymph Node Syndrome, Sağlık Bilimleri, Pediatrics, Clinical Medicine (MED), DISEASE, Çocuk Sağlığı ve Hastalıkları, Child Health and Diseases, Health Sciences, Diagnosis, Humans, Klinik Tıp (MED), Glucocorticoids, Kawasaki-Disease, Fatigue, Retrospective Studies, child, Internal Medicine Sciences, Klinik Tıp, Kawasaki disease, SARS-CoV-2, Immunoglobulins, Intravenous, COVID-19, Dahili Tıp Bilimleri, CLINICAL MEDICINE, Systemic Inflammatory Response Syndrome, Tıp, Pediatrics, Perinatology and Child Health, Medicine, Female, PEDİATRİ, Receptor
Abstract

© 2022 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).Aim: Multisystem inflammatory syndrome in children (MIS-C) may cause shock and even death in children. The aim of this study is to describe the clinical features, laboratory characteristics and outcome of children diagnosed with MIS-C in 25 different hospitals in Turkey. Methods: The retrospective study was conducted between 8 April and 28 October 2020 in 25 different hospitals from 17 cities. Data were collected from patients' medical records using a standardised form. Clinical and laboratory characteristics and outcomes according to different age groups, gender and body mass index percentiles were compared using multivariate logistic regression analysis. Results: The study comprised 101 patients, median age 7 years (interquartile range (IQR) 4.6–9.3); 51 (50.5%) were boys. Reverse-transcriptase polymerase chain reaction (PCR) assay was positive in 21/100 (21%) patients; 62/83 (74.6%) patients had positive serology for SARS-CoV-2. The predominant complaints were fever (100%), fatigue (n = 90, 89.1%), and gastrointestinal symptoms (n = 81, 80.2%). Serum C-reactive protein (in 101 patients, median 165 mg/L; range 112–228), erythrocyte sedimentation rate (73/84, median 53 mm/s; IQR 30–84) and procalcitonin levels (86/89, median 5 μg/L; IQR 0.58–20.2) were elevated. Thirty-eight patients (37.6%) required admission to intensive care. Kawasaki disease (KD) was diagnosed in 70 (69.3%) patients, 40 of whom had classical KD. Most patients were treated with intravenous immunoglobulin (n = 92, 91%) and glucocorticoids (n = 59, 58.4%). Seven patients (6.9%) died. Conclusion: The clinical spectrum of MIS-C is broad, but clinicians should consider MIS-C in the differential diagnosis when persistent fever, fatigue and gastrointestinal symptoms are prominent. Most patients diagnosed with MIS-C were previously healthy. Immunomodulatory treatment and supportive intensive care are important in the management of cases with MIS-C. Glucocorticoids and intravenous immunoglobulins are the most common immunomodulatory treatment options for MIS-C. Prompt diagnosis and prompt treatment are essential for optimal management.

Published
2022

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