425 results on '"Dorman, M"'
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2. ASO Visual Abstract: The Role of Adjuvant Use of the PlasmaJet® Device During Cytoreductive Surgery for Advanced-Stage Ovarian Cancer—Results of the PlaComOv-Study, a Randomized, Controlled Trial in the Netherlands
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Nieuwenhuyzen-de Boer, G. M., Hofhuis, W., Reesink-Peters, N., Willemsen, S., Boere, I. A., Schoots, I. G., Piek, J. M. J., Hofman, L. N., Beltman, J. J., van Driel, W. J., Werner, H. M. J., Baalbergen, A., van Haaften-de Jong, A. M. L. D., Dorman, M., Haans, L., Nedelcu, I., Ewing-Graham, P. C., and van Beekhuizen, H. J.
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- 2022
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3. Search for the disappearance of muon antineutrinos in the NuMI neutrino beam
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MINOS Collaboration, Adamson, P., Auty, D. J., Ayres, D. S., Backhouse, C., Barr, G., Bishai, M., Blake, A., Bock, G. J., Boehnlein, D. J., Bogert, D., Cao, S. V., Cavanaugh, S., Cherdack, D., Childress, S., Choudhary, B. C., Coelho, J. A. B., Coleman, S. J., Corwin, L., Cronin-Hennessy, D., Danko, I. Z., de Jong, J. K., Devenish, N. E., Diwan, M. V., Dorman, M., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Frohne, M. V., Gallagher, H. R., Gomes, R. A., Goodman, M. C., Gouffon, P., Graf, N., Gran, R., Grant, N., Grzelak, K., Habig, A., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Howcroft, C., Huang, X., Hylen, J., Irwin, G. M., Isvan, Z., Jaffe, D. E., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koizumi, G., Kopp, S., Kordosky, M., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P. J., Loiacono, L., Lucas, P., Mann, W. A., Marshak, M. L., Mathis, M., Mayer, N., Mehdiyev, R., Meier, J. R., Messier, M. D., Michael, D. G., Miller, W. H., Mishra, S. R., Mitchell, J., Moore, C. D., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Nowak, J. A., Ochoa-Ricoux, J. P., Oliver, W. P., Orchanian, M., Pahlka, R., Paley, J., Patterson, R. B., Pawloski, G., Pearce, G. F., Phan-Budd, S., Plunkett, R. K., Qiu, X., Ratchford, J., Rebel, B., Rosenfeld, C., Rubin, H. A., Sanchez, M. C., Schneps, J., Schreckenberger, A., Schreiner, P., Sharma, R., Sousa, A., Strait, M., Tagg, N., Talaga, R. L., Tavera, M. A., Thomas, J., Thomson, M. A., Tinti, G., Toner, R., Torretta, D., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Walding, J. J., Weber, A., Webb, R. C., White, C., Whitehead, L., Wojcicki, S. G., Yang, T., and Zwaska, R.
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High Energy Physics - Experiment - Abstract
We report constraints on antineutrino oscillation parameters that were obtained by using the two MINOS detectors to measure the 7% muon antineutrino component of the NuMI neutrino beam. In the Far Detector, we select 130 events in the charged-current muon antineutrino sample, compared to a prediction of 136.4 +/- 11.7(stat) ^{+10.2}_{-8.9}(syst) events under the assumption |dm2bar|=2.32x10^-3 eV^2, snthetabar=1.0. Assuming no oscillations occur at the Near Detector baseline, a fit to the two-flavor oscillation approximation constrains |dm2bar|<3.37x10^-3 eV^2 at the 90% confidence level with snthetabar=1.0., Comment: Accepted for publication by Phys. Rev. D Rapid Communications. 6 pages, 4 figures
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- 2011
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4. Improved search for muon-neutrino to electron-neutrino oscillations in MINOS
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MINOS Collaboration, Adamson, P., Auty, D. J., Ayres, D. S., Backhouse, C., Barr, G., Betancourt, M., Bishai, M., Blake, A., Bock, G. J., Boehnlein, D. J., Bogert, D., Cao, S. V., Cavanaugh, S., Cherdack, D., Childress, S., Coelho, J. A. B., Corwin, L., Cronin-Hennessy, D., Danko, I. Z., de Jong, J. K., Devenish, N. E., Diwan, M. V., Dorman, M., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Frohne, M. V., Gallagher, H. R., Gomes, R. A., Goodman, M. C., Gouffon, P., Graf, N., Gran, R., Grzelak, K., Habig, A., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Huang, X., Hylen, J., Irwin, G. M., Isvan, Z., Jaffe, D. E., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koizumi, G., Kopp, S., Kordosky, M., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P. J., Loiacono, L., Lucas, P., Mann, W. A., Marshak, M. L., Mathis, M., Mayer, N., McGowan, A. M., Mehdiyev, R., Meier, J. R., Messier, M. D., Michael, D. G., Miller, W. H., Mishra, S. R., Mitchell, J., Moore, C. D., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Nowak, J. A., Ochoa-Ricoux, J. P., Oliver, W. P., Orchanian, M., Paley, J., Patterson, R. B., Pawloski, G., Pearce, G. F., Phan-Budd, S., Plunkett, R. K., Qiu, X., Ratchford, J., Rebel, B., Rosenfeld, C., Rubin, H. A., Sanchez, M. C., Schneps, J., Schreckenberger, A., Schreiner, P., Shanahan, P., Sharma, R., Sousa, A., Tagg, N., Talaga, R. L., Thomas, J., Thomson, M. A., Toner, R., Torretta, D., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Walding, J. J., Weber, A., Webb, R. C., White, C., Whitehead, L., Wojcicki, S. G., Yang, T., and Zwaska, R.
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High Energy Physics - Experiment - Abstract
We report the results of a search for $\nu_{e}$ appearance in a $\nu_{\mu}$ beam in the MINOS long-baseline neutrino experiment. With an improved analysis and an increased exposure of $8.2\times10^{20}$ protons on the NuMI target at Fermilab, we find that $2\sin^2(\theta_{23})\sin^2(2\theta_{13})<0.12\ (0.20)$ at 90% confidence level for $\delta\mathord{=}0$ and the normal (inverted) neutrino mass hierarchy, with a best fit of $2\sin^2(\theta_{23})\sin^2(2\theta_{13})\,\mathord{=}\,0.041^{+0.047}_{-0.031}\ (0.079^{+0.071}_{-0.053})$. The $\theta_{13}\mathord{=}0$ hypothesis is disfavored by the MINOS data at the 89% confidence level., Comment: 5 pages, 3 figures
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- 2011
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5. Active to sterile neutrino mixing limits from neutral-current interactions in MINOS
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MINOS Collaboration, Adamson, P., Auty, D. J., Ayres, D. S., Backhouse, C., Barr, G., Bishai, M., Blake, A., Bock, G. J., Boehnlein, D. J., Bogert, D., Cavanaugh, S., Cherdack, D., Childress, S., Coelho, J. A. B., Coleman, S. J., Corwin, L., Cronin-Hennessy, D., Danko, I. Z., de Jong, J. K., Devenish, N. E., Diwan, M. V., Dorman, M., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Frohne, M. V., Gallagher, H. R., Gomes, R. A., Goodman, M. C., Gouffon, P., Graf, N., Gran, R., Grant, N., Grzelak, K., Habig, A., Harris, D., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Huang, X., Hylen, J., Ilic, J., Irwin, G. M., Isvan, Z., Jaffe, D. E., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koizumi, G., Kopp, S., Kordosky, M., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P. J., Loiacono, L., Lucas, P., Mann, W. A., Marshak, M. L., Mayer, N., McGowan, A. M., Mehdiyev, R., Meier, J. R., Messier, M. D., Miller, W. H., Mishra, S. R., Mitchell, J., Moore, C. D., Morfín, J., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Nicholls, T. C., Nowak, J. A., Oliver, W. P., Orchanian, M., Paley, J., Patterson, R. B., Pawloski, G., Pearce, G. F., Petyt, D. A., Phan-Budd, S., Pittam, R., Plunkett, R. K., Qiu, X., Ratchford, J., Raufer, T. M., Rebel, B., Rodrigues, P. A., Rosenfeld, C., Sanchez, H. A. Rubin M. C., Schneps, J., Schreiner, P., Sharma, R., Shanahan, P., Sousa, A., Stamoulis, P., Strait, M., Tagg, N., Talaga, R. L., Tetteh-Lartey, E., Thomas, J., Thomson, M. A., Tinti, G., Toner, R., Torretta, D., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Walding, J. J., Weber, A., Webb, R. C., White, C., Whitehead, L., Wojcicki, S. G., and Zwaska, R.
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High Energy Physics - Experiment - Abstract
Results are reported from a search for active to sterile neutrino oscillations in the MINOS long-baseline experiment, based on the observation of neutral-current neutrino interactions, from an exposure to the NuMI neutrino beam of $7.07\times10^{20}$ protons on target. A total of 802 neutral-current event candidates is observed in the Far Detector, compared to an expected number of $754\pm28\rm{(stat.)}\pm{37}\rm{(syst.)}$ for oscillations among three active flavors. The fraction $f_s$ of disappearing \numu that may transition to $\nu_s$ is found to be less than 22% at the 90% C.L., Comment: 5 pages, 3 tables, 2 figures. Published in Physical Review Letters
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- 2011
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6. First direct observation of muon antineutrino disappearance
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MINOS collaboration, Adamson, P., Andreopoulos, C., Auty, D. J., Ayres, D. S., Backhouse, C., Barr, G., Bishai, M., Blake, A., Bock, G. J., Boehnlein, D. J., Bogert, D., Cavanaugh, S., Cherdack, D., Childress, S., Choudhary, B. C., Coelho, J. A. B., Coleman, S. J., Corwin, L., Cronin-Hennessy, D., Danko, I. Z., de Jong, J. K., Devenish, N. E., Diwan, M. V., Dorman, M., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Frohne, M. V., Gallagher, H. R., Gomes, R. A., Goodman, M. C., Gouffon, P., Graf, N., Gran, R., Grant, N., Grzelak, K., Habig, A., Harris, D., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Howcroft, C., Huang, X., Hylen, J., Ilic, J., Irwin, G. M., Isvan, Z., Jaffe, D. E., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koizumi, G., Kopp, S., Kordosky, M., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P. J., Loiacono, L., Lucas, P., Mann, W. A., Marshak, M. L., Mayer, N., McGowan, A. M., Mehdiyev, R., Meier, J. R., Messier, M. D., Miller, W. H., Mishra, S. R., Mitchell, J., Moore, C. D., Morfín, J., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Nicholls, T. C., Nowak, J. A., Ochoa-Ricoux, J. P., Oliver, W. P., Orchanian, M., Ospanov, R., Paley, J., Patterson, R. B., Pawloski, G., Pearce, G. F., Petyt, D. A., Phan-Budd, S., Plunkett, R. K., Qiu, X., Ratchford, J., Raufer, T. M., Rebel, B., Rodrigues, P. A., Rosenfeld, C., Rubin, H. A., Sanchez, M. C., Schneps, J., Schreiner, P., Shanahan, P., Sousa, A., Stamoulis, P., Strait, M., Tagg, N., Talaga, R. L., Tetteh-Lartey, E., Thomas, J., Thomson, M. A., Tinti, G., Toner, R., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Weber, A., Webb, R. C., White, C., Whitehead, L., Wojcicki, S. G., Yang, T., and Zwaska, R.
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High Energy Physics - Experiment - Abstract
This letter reports the first direct observation of muon antineutrino disappearance. The MINOS experiment has taken data with an accelerator beam optimized for muon antineutrino production, accumulating an exposure of $1.71\times 10^{20}$ protons on target. In the Far Detector, 97 charged current muon antineutrino events are observed. The no-oscillation hypothesis predicts 156 events and is excluded at $6.3\sigma$. The best fit to oscillation yields $\Delta \bar{m}^{2}=(3.36^{+0.46}_{-0.40}\textrm{(stat.)}\pm0.06\textrm{(syst.)})\times 10^{-3}\,\eV^{2}$, $\sin^{2}(2\bar{\theta})=0.86^{+0.11}_{-0.12}\textrm{(stat.)}\pm0.01\textrm{(syst.)}$. The MINOS muon neutrino and muon antineutrino measurements are consistent at the 2.0% confidence level, assuming identical underlying oscillation parameters., Comment: Six pages, four figures. This version published by Physical Review Letters
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- 2011
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7. Measurement of the neutrino mass splitting and flavor mixing by MINOS
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The MINOS Collaboration, Adamson, P., Andreopoulos, C., Armstrong, R., Auty, D. J., Ayres, D. S., Backhouse, C., Barr, G., Bishai, M., Blake, A., Bock, G. J., Boehnlein, D. J., Bogert, D., Cavanaugh, S., Cherdack, D., Childress, S., Choudhary, B. C., Coelho, J. A. B., Coleman, S. J., Corwin, L., Cronin-Hennessy, D., Danko, I. Z., de Jong, J. K., Devenish, N. E., Diwan, M. V., Dorman, M., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Frohne, M. V., Gallagher, H. R., Gomes, R. A., Goodman, M. C., Gouffon, P., Graf, N., Gran, R., Grant, N., Grzelak, K., Habig, A., Harris, D., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Huang, X., Hylen, J., Ilic, J., Irwin, G. M., Isvan, Z., Jaffe, D. E., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koizumi, G., Kopp, S., Kordosky, M., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P. J., Litchfield, R. P., Loiacono, L., Lucas, P., Mann, W. A., Marshak, M. L., Mayer, N., McGowan, A. M., Mehdiyev, R., Meier, J. R., Messier, M. D., Michael, D. G., Miller, W. H., Mishra, S. R., Mitchell, J., Moore, C. D., Morfín, J., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Nowak, J. A., Oliver, W. P., Orchanian, M., Ospanov, R., Paley, J., Patterson, R. B., Pawloski, G., Pearce, G. F., Petyt, D. A., Phan-Budd, S., Plunkett, R. K., Qiu, X., Ratchford, J., Raufer, T. M., Rebel, B., Rodrigues, P. A., Rosenfeld, C., Rubin, H. A., Sanchez, M. C., Schneps, J., Schreiner, P., Shanahan, P., Smith, C., Sousa, A., Stamoulis, P., Strait, M., Tagg, N., Talaga, R. L., Thomas, J., Thomson, M. A., Tinti, G., Toner, R., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Weber, A., Webb, R. C., White, C., Whitehead, L., Wojcicki, S. G., Yang, T., and Zwaska, R.
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High Energy Physics - Experiment - Abstract
Measurements of neutrino oscillations using the disappearance of muon neutrinos from the Fermilab NuMI neutrino beam as observed by the two MINOS detectors are reported. New analysis methods have been applied to an enlarged data sample from an exposure of $7.25 \times 10^{20}$ protons on target. A fit to neutrino oscillations yields values of $|\Delta m^2| = (2.32^{+0.12}_{-0.08})\times10^{-3}$\,eV$^2$ for the atmospheric mass splitting and $\rm \sin^2\!(2\theta) > 0.90$ (90%\,C.L.) for the mixing angle. Pure neutrino decay and quantum decoherence hypotheses are excluded at 7 and 9 standard deviations, respectively., Comment: 5 pages, 4 figures
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- 2011
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8. A Search for Lorentz Invariance and CPT Violation with the MINOS Far Detector
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MINOS Collaboration, Adamson, P., Auty, D. J., Ayres, D. S., Backhouse, C., Barr, G., Barrett, W. L., Bishai, M., Blake, A., Bock, G. J., Boehnlein, D. J., Bogert, D., Bower, C., Budd, S., Cavanaugh, S., Cherdack, D., Childress, S., Choudhary, B. C., Coelho, J. A. B., Cobb, J. H., Coleman, S. J., Corwin, L., Cravens, J. P., Cronin-Hennessy, D., Danko, I. Z., de Jong, J. K., Devenish, N. E., Diwan, M. V., Dorman, M., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Frohne, M. V., Gallagher, H. R., Gomes, R. A., Goodman, M. C., Gouffon, P., Gran, R., Grant, N., Grzelak, K., Habig, A., Harris, D., Harris, P. G., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Huang, X., Hylen, J., Ilic, J., Irwin, G. M., Isvan, Z., Jaffe, D. E., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koizumi, G., Kopp, S., Kordosky, M., Krahn, Z., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P. J., Loiacono, L., Lucas, P., Mann, W. A., Marshak, M. L., Mayer, N., McGowan, A. M., Mehdiyev, R., Meier, J. R., Messier, M. D., Michael, D. G., Miller, J. L., Miller, W. H., Mishra, S. R., Mitchell, J., Moore, C. D., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Oliver, W. P., Orchanian, M., Paley, J., Patterson, R. B., Patzak, T., Pawloski, G., Pearce, G. F., Pittam, R., Plunkett, R. K., Ratchford, J., Raufer, T. M., Rebel, B., Rodrigues, P. A., Rosenfeld, C., Rubin, H. A., Ryabov, V. A., Sanchez, M. C., Saoulidou, N., Schneps, J., Schreiner, P., Semenov, V. K., Shanahan, P., Smart, W., Sousa, A., Strait, M., Tagg, N., Talaga, R. L., Thomas, J., Thomson, M. A., Tinti, G., Toner, R., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Weber, A., Webb, R. C., White, C., Whitehead, L., Wojcicki, S. G., Wright, D. M., Yang, T., Zois, M., and Zwaska, R.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology - Abstract
We searched for a sidereal modulation in the MINOS far detector neutrino rate. Such a signal would be a consequence of Lorentz and CPT violation as described by the Standard-Model Extension framework. It also would be the first detection of a perturbative effect to conventional neutrino mass oscillations. We found no evidence for this sidereal signature and the upper limits placed on the magnitudes of the Lorentz and CPT violating coefficients describing the theory are an improvement by factors of $20-510$ over the current best limits found using the MINOS near detector., Comment: 5 pages, 2 figures
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- 2010
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9. Lock-in Thermography for the Wide Area Detection of Paint Degradation and Incipient Corrosion
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Jones, R., primary, Lo, M., additional, Dorman, M., additional, Bowler, A., additional, Roles, D., additional, and Wade, S.A., additional
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- 2019
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10. Evaluation of effectiveness of the PlasmaJet surgical device in the treatment of advanced stage ovarian cancer (PlaComOv-study): study protocol of a randomized controlled trial in the Netherlands
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Nieuwenhuyzen-de Boer, G. M., Hofhuis, W., Reesink-Peters, N., Ewing-Graham, P. C., Schoots, I. G., Beltman, J. J., Piek, J. M. J., Baalbergen, A., Kooi, G. S., van Haaften, A., van Huisseling, H., Haans, L., Dorman, M., and van Beekhuizen, H. J.
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- 2019
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11. Pre-and post-drought conditions drive resilience of Pinus halepensis across its distribution range
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Agence de la Transition Écologique (France), Aix-Marseille Université, Ministère de l'Agriculture, de l'Agroalimentaire et de la Forêt (France), European Commission, Universidad de Valladolid, Junta de Castilla y León, Ministerio de Ciencia e Innovación (España), Slovenian Research Agency, Ministero dell'Istruzione, dell'Università e della Ricerca, Ministry of Agriculture & Rural Development (Israel), University of Patras, Ministerio de Economía, Industria y Competitividad (España), Veuillen, Léa [0000-0002-2790-3627], Prévosto, Bernard [0000-0002-8470-080X], Alfaro-Sánchez, R. [0000-0001-7357-3027], Badeau, Vincent [0000-0003-2832-7315], Battipaglia, G. [0000-0003-1741-3509], Beguería, Santiago [0000-0002-3974-2947], Bravo, Felipe [0000-0001-7348-6695], Camarero, Jesús Julio [0000-0003-2436-2922], Cufar, Katarina [0000-0002-7403-3994], Davi, Hendrik [0000-0001-8828-3145], De Luis, Martin [0000-0002-7585-3636], Del Campo, A. [0000-0002-5279-4215], del Rio, Miren [0000-0001-7496-3713], Di Filippo, A. [0000-0001-5863-8339], Ferrio, J. P. [0000-0001-5904-7821], Gea Izquierdo, Guillermo [0000-0003-0148-3721], González-Sanchis, Maria [0000-0002-2227-8404], Granda, Elena [0000-0002-9559-4213], Gutiérrez, Emilia [0000-0002-6085-5700], Helluy, Manon [0000-0001-5263-7503], Klein, Tamir [0000-0002-3882-8845], Levillain, Joseph [0000-0002-9644-7696], Manrique-Alba, Angela [0000-0002-7255-4999], Martínez-Vilalta, Jordi [0000-0002-2332-7298], Moreno-Gutiérrez, Cristina [0000-0002-2788-581X], Olivar, Jorge [0000-0003-0193-6612], Papadopoulos, A. [0000-0001-8138-5536], Perevolotsky, Avi [0000-0001-8499-5372], Rathgeber, Cyrille [0000-0001-7359-8320], Ripullone, Francesco [0000-0003-4851-3422], Ruano, Irene [0000-0003-4059-1928], Sánchez-Salguero, R. [0000-0002-6545-5810], Serra-Maluquer, Xavier [0000-0002-1880-0511], Svoray, Tal [0000-0003-2243-8532], Valor, Teresa [0000-0002-3986-256X], Vennetier, Michel [0000-0002-7549-5701], Cailleret, Maxime [0000-0001-6561-1943], Veuillen, Léa, Prévosto, Bernard, Alfaro-Sánchez, R., Badeau, Vincent, Battipaglia, G., Beguería, Santiago, Bravo, Felipe, Boivin, Thomas, Camarero, Jesús Julio, Cufar, Katarina, Davi, Hendrik, De Luis, Martin, Del Campo, A., Río, Miren del, Di Filippo, A., Dorman, M., Durand-Gillmann, Marion, Ferrio, J. P., Gea Izquierdo, Guillermo, González-Sanchis, Maria, Granda, Elena, Guibal, Frederic, Gutiérrez, Emilia, Helluy, Manon, El Khorchani, Ali, Klein, T., Levillain, Joseph, Linares, Juan Carlos, Manrique-Alba, Ángela, Martínez-Vilalta, Jordi, Molina, Antonio, Moreno-Gutiérrez, Cristina, Nicault, A., Olivar, Jorge, Papadopoulos, A., Perevolotsky, Avi, Rathgeber, Cyrille, Ribas, Montse, Ripullone, Francesco, Ruano, Irene, Saintonge, Francois Xavier, Sánchez-Salguero, Raúl, Sarris, Dimitrios, Serra-Maluquer, Xavier, Svoray, Tal, Tallieu, Clara, Valor, Teresa, Vennetier, Michel, Voltas, Jordi, Cailleret, Maxime, Agence de la Transition Écologique (France), Aix-Marseille Université, Ministère de l'Agriculture, de l'Agroalimentaire et de la Forêt (France), European Commission, Universidad de Valladolid, Junta de Castilla y León, Ministerio de Ciencia e Innovación (España), Slovenian Research Agency, Ministero dell'Istruzione, dell'Università e della Ricerca, Ministry of Agriculture & Rural Development (Israel), University of Patras, Ministerio de Economía, Industria y Competitividad (España), Veuillen, Léa [0000-0002-2790-3627], Prévosto, Bernard [0000-0002-8470-080X], Alfaro-Sánchez, R. [0000-0001-7357-3027], Badeau, Vincent [0000-0003-2832-7315], Battipaglia, G. [0000-0003-1741-3509], Beguería, Santiago [0000-0002-3974-2947], Bravo, Felipe [0000-0001-7348-6695], Camarero, Jesús Julio [0000-0003-2436-2922], Cufar, Katarina [0000-0002-7403-3994], Davi, Hendrik [0000-0001-8828-3145], De Luis, Martin [0000-0002-7585-3636], Del Campo, A. [0000-0002-5279-4215], del Rio, Miren [0000-0001-7496-3713], Di Filippo, A. [0000-0001-5863-8339], Ferrio, J. P. [0000-0001-5904-7821], Gea Izquierdo, Guillermo [0000-0003-0148-3721], González-Sanchis, Maria [0000-0002-2227-8404], Granda, Elena [0000-0002-9559-4213], Gutiérrez, Emilia [0000-0002-6085-5700], Helluy, Manon [0000-0001-5263-7503], Klein, Tamir [0000-0002-3882-8845], Levillain, Joseph [0000-0002-9644-7696], Manrique-Alba, Angela [0000-0002-7255-4999], Martínez-Vilalta, Jordi [0000-0002-2332-7298], Moreno-Gutiérrez, Cristina [0000-0002-2788-581X], Olivar, Jorge [0000-0003-0193-6612], Papadopoulos, A. [0000-0001-8138-5536], Perevolotsky, Avi [0000-0001-8499-5372], Rathgeber, Cyrille [0000-0001-7359-8320], Ripullone, Francesco [0000-0003-4851-3422], Ruano, Irene [0000-0003-4059-1928], Sánchez-Salguero, R. [0000-0002-6545-5810], Serra-Maluquer, Xavier [0000-0002-1880-0511], Svoray, Tal [0000-0003-2243-8532], Valor, Teresa [0000-0002-3986-256X], Vennetier, Michel [0000-0002-7549-5701], Cailleret, Maxime [0000-0001-6561-1943], Veuillen, Léa, Prévosto, Bernard, Alfaro-Sánchez, R., Badeau, Vincent, Battipaglia, G., Beguería, Santiago, Bravo, Felipe, Boivin, Thomas, Camarero, Jesús Julio, Cufar, Katarina, Davi, Hendrik, De Luis, Martin, Del Campo, A., Río, Miren del, Di Filippo, A., Dorman, M., Durand-Gillmann, Marion, Ferrio, J. P., Gea Izquierdo, Guillermo, González-Sanchis, Maria, Granda, Elena, Guibal, Frederic, Gutiérrez, Emilia, Helluy, Manon, El Khorchani, Ali, Klein, T., Levillain, Joseph, Linares, Juan Carlos, Manrique-Alba, Ángela, Martínez-Vilalta, Jordi, Molina, Antonio, Moreno-Gutiérrez, Cristina, Nicault, A., Olivar, Jorge, Papadopoulos, A., Perevolotsky, Avi, Rathgeber, Cyrille, Ribas, Montse, Ripullone, Francesco, Ruano, Irene, Saintonge, Francois Xavier, Sánchez-Salguero, Raúl, Sarris, Dimitrios, Serra-Maluquer, Xavier, Svoray, Tal, Tallieu, Clara, Valor, Teresa, Vennetier, Michel, Voltas, Jordi, and Cailleret, Maxime
- Abstract
Severe droughts limit tree growth and forest productivity worldwide, a phenomenon which is expected to aggravate over the next decades. However, how drought intensity and climatic conditions before and after drought events modulate tree growth resilience remains unclear, especially when considering the range-wide phenotypic variability of a tree species. We gathered 4632 Aleppo pine (Pinus halepensis Mill.) tree-ring width series from 281 sites located in 11 countries across the Mediterranean basin, representing the entire geographic and bioclimatic range of the species. For each site and year of the period 1950–2020, we quantified tree-growth resilience and its two components, resistance and recovery, to account for the impact of drought and the capacity to recover from it. Relative drought intensity of each year was assessed using SPEI (Standardized Precipitation Evapotranspiration Index), a climatic water deficit index. Generalized additive mixed models were used to explore the non-linear relationships between resilience and its two components and drought intensity, preceding and following years climatic conditions. We found that P. halepensis radial growth was highly dependent on the SPEI from September of the previous year to June of the current year. Trees growing under more arid bioclimates showed higher inter-annual growth variability and were more sensitive to drought, resulting in an increased response magnitude to pre-, during and post-drought conditions. In contrast to our expectations, drought intensity only slightly affected resilience, which was rather negatively affected by favorable preceding conditions and improved by favorable following conditions. Resilience and its components are highly dependent on preceding and following years climatic conditions, which should always be taken into account when studying growth response to drought. With the observed and predicted increase in drought frequency, duration and intensity, favorable conditions followi
- Published
- 2023
12. Effect of laser shock peening on residual stress and fatigue life of clad 2024 aluminium sheet containing scribe defects
- Author
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Dorman, M., Toparli, M.B., Smyth, N., Cini, A., Fitzpatrick, M.E., and Irving, P.E.
- Published
- 2012
- Full Text
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13. SARS-CoV-2 evolution during treatment of chronic infection
- Author
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Kemp, S. A., Collier, D. A., Datir, R. P., Ferreira, I. A. T. M., Gayed, S., Jahun, A., Hosmillo, M., Rees-Spear, C., Mlcochova, P., Lumb, I. U., Roberts, D. J., Chandra, A., Temperton, N., Baker, S., Dougan, G., Hess, C., Kingston, N., Lehner, P. J., Lyons, P. A., Matheson, N. J., Owehand, W. H., Saunders, C., Summers, C., Thaventhiran, J. E. D., Toshner, M., Weekes, M. P., Bucke, A., Calder, J., Canna, L., Domingo, J., Elmer, A., Fuller, S., Harris, J., Hewitt, S., Kennet, J., Jose, S., Kourampa, J., Meadows, A., O'Brien, C., Price, J., Publico, C., Rastall, R., Ribeiro, C., Rowlands, J., Ruffolo, V., Tordesillas, H., Bullman, B., Dunmore, B. J., Fawke, S., Graf, S., Hodgson, J., Huang, C., Hunter, K., Jones, E., Legchenko, E., Matara, C., Martin, J., Mescia, F., O'Donnell, C., Pointon, L., Pond, N., Shih, J., Sutcliffe, R., Tilly, T., Treacy, C., Tong, Z., Wood, J., Wylot, M., Bergamaschi, L., Betancourt, A., Bower, G., Cossetti, C., De Sa, A., Epping, M., Gleadall, N., Grenfell, R., Hinch, A., Huhn, O., Jackson, S., Jarvis, I., Lewis, D., Marsden, J., Nice, F., Okecha, G., Omarjee, O., Perera, M., Richoz, N., Romashova, V., Yarkoni, N. S., Sharma, R., Stefanucci, L., Stephens, J., Strezlecki, M., Turner, L., De Bie, E. M. D. D., Bunclark, K., Josipovic, M., Mackay, M., Rossi, S., Selvan, M., Spencer, S., Yong, C., Ansaripour, A., Michael, A., Mwaura, L., Patterson, C., Polwarth, G., Polgarova, P., di Stefano, G., Fahey, C., Michel, R., Bong, S. -H., Coudert, J. D., Holmes, E., Allison, J., Butcher, H., Caputo, D., Clapham-Riley, D., Dewhurst, E., Furlong, A., Graves, B., Gray, J., Ivers, T., Kasanicki, M., Le Gresley, E., Linger, R., Meloy, S., Muldoon, F., Ovington, N., Papadia, S., Phelan, I., Stark, H., Stirrups, K. E., Townsend, P., Walker, N., Webster, J., Robson, S. C., Loman, N. J., Connor, T. R., Golubchik, T., Martinez Nunez, R. T., Ludden, C., Corden, S., Johnston, I., Bonsall, D., Smith, C. P., Awan, A. R., Bucca, G., Estee Torok, M., Saeed, K., Prieto, J. A., Jackson, D. K., Hamilton, W. L., Snell, L. B., Moore, C., Harrison, E. M., Goncalves, S., Fairley, D. J., Loose, M. W., Watkins, J., Livett, R., Moses, S., Amato, R., Nicholls, S., Bull, M., Smith, D. L., Barrett, J., Aanensen, D. M., Curran, M. D., Parmar, S., Aggarwal, D., Shepherd, J. G., Parker, M. D., Glaysher, S., Bashton, M., Underwood, A. P., Pacchiarini, N., Loveson, K. F., Carabelli, A. M., Templeton, K. E., Langford, C. F., Sillitoe, J., de Silva, T. I., Wang, D., Kwiatkowski, D., Rambaut, A., O'Grady, J., Cottrell, S., Holden, M. T. G., Thomson, E. C., Osman, H., Andersson, M., Chauhan, A. J., Hassan-Ibrahim, M. O., Lawniczak, M., Alderton, A., Chand, M., Constantinidou, C., Unnikrishnan, M., Darby, A. C., Hiscox, J. A., Paterson, S., Martincorena, I., Robertson, D. L., Volz, E. M., Page, A. J., Pybus, O. G., Bassett, A. R., Ariani, C. V., Spencer Chapman, M. H., K. K., Li, Shah, R. N., Jesudason, N. G., Taha, Y., Mchugh, M. P., Dewar, R., Jahun, A. S., Mcmurray, C., Pandey, S., Mckenna, J. P., Nelson, A., Young, G. R., Mccann, C. M., Elliott, S., Lowe, H., Temperton, B., Roy, S., Price, A., Rey, S., Wyles, M., Rooke, S., Shaaban, S., de Cesare, M., Letchford, L., Silveira, S., Pelosi, E., Wilson-Davies, E., O'Toole, A., Hesketh, A. R., Stark, R., du Plessis, L., Ruis, C., Adams, H., Bourgeois, Y., Michell, S. L., Gramatopoulos, D., Edgeworth, J., Breuer, J., Todd, J. A., Fraser, C., Buck, D., John, M., Kay, G. L., Palmer, S., Peacock, S. J., Heyburn, D., Weldon, D., Robinson, E., Mcnally, A., Muir, P., Vipond, I. B., Boyes, J., Sivaprakasam, V., Salluja, T., Dervisevic, S., Meader, E. J., Park, N. R., Oliver, K., Jeffries, A. R., Ott, S., da Silva Filipe, A., Simpson, D. A., Williams, C., Masoli, J. A. H., Knight, B. A., Jones, C. R., Koshy, C., Ash, A., Casey, A., Bosworth, A., Ratcliffe, L., Xu-McCrae, L., Pymont, H. M., Hutchings, S., Berry, L., Jones, K., Halstead, F., Davis, T., Holmes, C., Iturriza-Gomara, M., Lucaci, A. O., Randell, P. A., Cox, A., Madona, P., Harris, K. A., Brown, J. R., Mahungu, T. W., Irish-Tavares, D., Haque, T., Hart, J., Witele, E., Fenton, M. L., Liggett, S., Graham, C., Swindells, E., Collins, J., Eltringham, G., Campbell, S., Mcclure, P. C., Clark, G., Sloan, T. J., Jones, C., Lynch, J., Warne, B., Leonard, S., Durham, J., Williams, T., Haldenby, S. T., Storey, N., Alikhan, N. -F., Holmes, N., Carlile, M., Perry, M., Craine, N., Lyons, R. A., Beckett, A. H., Goudarzi, S., Fearn, C., Cook, K., Dent, H., Paul, H., Davies, R., Blane, B., Girgis, S. T., Beale, M. A., Bellis, K. L., Dorman, M. J., Drury, E., Kane, L., Kay, S., Mcguigan, S., Nelson, R., Prestwood, L., Rajatileka, S., Batra, R., Williams, R. J., Kristiansen, M., Green, A., Justice, A., Mahanama, A. I. K., Samaraweera, B., Hadjirin, N. F., Quick, J., Poplawski, R., Kermack, L. M., Reynolds, N., Hall, G., Chaudhry, Y., Pinckert, M. L., Georgana, I., Moll, R. J., Thornton, A., Myers, R., Stockton, J., Williams, C. A., Yew, W. C., Trotter, A. J., Trebes, A., MacIntyre-Cockett, G., Birchley, A., Adams, A., Plimmer, A., Gatica-Wilcox, B., Mckerr, C., Hilvers, E., Jones, H., Asad, H., Coombes, J., Evans, J. M., Fina, L., Gilbert, L., Graham, L., Cronin, M., Kumziene-Summerhayes, S., Taylor, S., Jones, S., Groves, D. C., Zhang, P., Gallis, M., Louka, S. F., Starinskij, I., Jackson, C., Gourtovaia, M., Tonkin-Hill, G., Lewis, K., Tovar-Corona, J. M., James, K., Baxter, L., Alam, M. T., Orton, R. J., Hughes, J., Vattipally, S., Ragonnet-Cronin, M., Nascimento, F. F., Jorgensen, D., Boyd, O., Geidelberg, L., Zarebski, A. E., Raghwani, J., Kraemer, M. U. G., Southgate, J., Lindsey, B. B., Freeman, T. M., Keatley, J. -P., Singer, J. B., de Oliveira Martins, L., Yeats, C. A., Abudahab, K., Taylor, B. E. W., Menegazzo, M., Danesh, J., Hogsden, W., Eldirdiri, S., Kenyon, A., Mason, J., Robinson, T. I., Holmes, A., Hartley, J. A., Curran, T., Mather, A. E., Shankar, G., Jones, R., Howe, R., Morgan, S., Wastenge, E., Chapman, M. R., Mookerjee, S., Stanley, R., Smith, W., Peto, T., Eyre, D., Crook, D., Vernet, G., Kitchen, C., Gulliver, H., Merrick, I., Guest, M., Munn, R., Bradley, D. T., Wyatt, T., Beaver, C., Foulser, L., Churcher, C. M., Brooks, E., Smith, K. S., Galai, K., Mcmanus, G. M., Bolt, F., Coll, F., Meadows, L., Attwood, S. W., Davies, A., De Lacy, E., Downing, F., Edwards, S., Scarlett, G. P., Jeremiah, S., Smith, N., Leek, D., Sridhar, S., Forrest, S., Cormie, C., Gill, H. K., Dias, J., Higginson, E. E., Maes, M., Young, J., Wantoch, M., Jamrozy, D., Lo, S., Patel, M., Hill, V., Bewshea, C. M., Ellard, S., Auckland, C., Harrison, I., Bishop, C., Chalker, V., Richter, A., Beggs, A., Best, A., Percival, B., Mirza, J., Megram, O., Mayhew, M., Crawford, L., Ashcroft, F., Moles-Garcia, E., Cumley, N., Hopes, R., Asamaphan, P., Niebel, M. O., Gunson, R. N., Bradley, A., Maclean, A., Mollett, G., Blacow, R., Bird, P., Helmer, T., Fallon, K., Tang, J., Hale, A. D., Macfarlane-Smith, L. R., Harper, K. L., Carden, H., Machin, N. W., Jackson, K. A., Ahmad, S. S. Y., George, R. P., Turtle, L., O'Toole, E., Watts, J., Breen, C., Cowell, A., Alcolea-Medina, A., Charalampous, T., Patel, A., Levett, L. J., Heaney, J., Rowan, A., Taylor, G. P., Shah, D., Atkinson, L., Lee, J. C. D., Westhorpe, A. P., Jannoo, R., Lowe, H. L., Karamani, A., Ensell, L., Chatterton, W., Pusok, M., Dadrah, A., Symmonds, A., Sluga, G., Molnar, Z., Baker, P., Bonner, S., Essex, S., Barton, E., Padgett, D., Scott, G., Greenaway, J., Payne, B. A. I., Burton-Fanning, S., Waugh, S., Raviprakash, V., Sheriff, N., Blakey, V., Williams, L. -A., Moore, J., Stonehouse, S., Smith, L., Davidson, R. K., Bedford, L., Coupland, L., Wright, V., Chappell, J. G., Tsoleridis, T., Ball, J., Khakh, M., Fleming, V. M., Lister, M. M., Howson-Wells, H. C., Boswell, T., Joseph, A., Willingham, I., Duckworth, N., Walsh, S., Wise, E., Moore, N., Mori, M., Cortes, N., Kidd, S., Williams, R., Gifford, L., Bicknell, K., Wyllie, S., Lloyd, A., Impey, R., Malone, C. S., Cogger, B. J., Levene, N., Monaghan, L., Keeley, A. J., Partridge, D. G., Raza, M., Evans, C., Johnson, K., Abnizova, I., Aigrain, L., Ali, M., Allen, L., Anderson, R., Ariani, C., Austin-Guest, S., Bala, S., Bassett, A., Battleday, K., Beal, J., Beale, M., Bellany, S., Bellerby, T., Bellis, K., Berger, D., Berriman, M., Betteridge, E., Bevan, P., Binley, S., Bishop, J., Blackburn, K., Bonfield, J., Boughton, N., Bowker, S., Brendler-Spaeth, T., Bronner, I., Brooklyn, T., Buddenborg, S. K., Bush, R., Caetano, C., Cagan, A., Carter, N., Cartwright, J., Monteiro, T. C., Chapman, L., Chillingworth, T. -J., Clapham, P., Clark, R., Clarke, A., Clarke, C., Cole, D., Cook, E., Coppola, M., Cornell, L., Cornwell, C., Corton, C., Crackett, A., Cranage, A., Craven, H., Craw, S., Crawford, M., Cutts, T., Dabrowska, M., Davies, M., Dawson, J., Day, C., Densem, A., Dibling, T., Dockree, C., Dodd, D., Dogga, S., Dougherty, M., Dove, A., Drummond, L., Dudek, M., Durrant, L., Easthope, E., Eckert, S., Ellis, P., Farr, B., Fenton, M., Ferrero, M., Flack, N., Fordham, H., Forsythe, G., Francis, M., Fraser, A., Freeman, A., Galvin, A., Garcia-Casado, M., Gedny, A., Girgis, S., Glover, J., Goodwin, S., Gould, O., Gray, A., Gray, E., Griffiths, C., Gu, Y., Guerin, F., Hamilton, W., Hanks, H., Harrison, E., Harrott, A., Harry, E., Harvison, J., Heath, P., Hernandez-Koutoucheva, A., Hobbs, R., Holland, D., Holmes, S., Hornett, G., Hough, N., Huckle, L., Hughes-Hallet, L., Hunter, A., Inglis, S., Iqbal, S., Jackson, A., Jackson, D., Verdejo, C. J., Jones, M., Kallepally, K., Kay, K., Keatley, J., Keith, A., King, A., Kitchin, L., Kleanthous, M., Klimekova, M., Korlevic, P., Krasheninnkova, K., Lane, G., Langford, C., Laverack, A., Law, K., Lensing, S., Lewis-Wade, A., Liddle, J., Lin, Q., Lindsay, S., Linsdell, S., Long, R., Lovell, J., Mack, J., Maddison, M., Makunin, A., Mamun, I., Mansfield, J., Marriott, N., Martin, M., Mayho, M., Mccarthy, S., Mcclintock, J., Mchugh, S., Mcminn, L., Meadows, C., Mobley, E., Moll, R., Morra, M., Morrow, L., Murie, K., Nash, S., Nathwani, C., Naydenova, P., Neaverson, A., Nerou, E., Nicholson, J., Nimz, T., Noell, G. G., O'Meara, S., Ohan, V., Olney, C., Ormond, D., Oszlanczi, A., Pang, Y. F., Pardubska, B., Park, N., Parmar, A., Patel, G., Payne, M., Peacock, S., Petersen, A., Plowman, D., Preston, T., Puethe, C., Quail, M., Rajan, D., Rance, R., Rawlings, S., Redshaw, N., Reynolds, J., Reynolds, M., Rice, S., Richardson, M., Roberts, C., Robinson, K., Robinson, M., Robinson, D., Rogers, H., Rojo, E. M., Roopra, D., Rose, M., Rudd, L., Sadri, R., Salmon, N., Saul, D., Schwach, F., Scott, C., Seekings, P., Shirley, L., Simms, A., Sinnott, M., Sivadasan, S., Siwek, B., Sizer, D., Skeldon, K., Skelton, J., Slater-Tunstill, J., Sloper, L., Smerdon, N., Smith, C., Smith, J., Smith, K., Smith, M., Smith, S., Smith, T., Sneade, L., Soria, C. D., Sousa, C., Souster, E., Sparkes, A., Spencer-Chapman, M., Squares, J., Steed, C., Stickland, T., Still, I., Stratton, M., Strickland, M., Swann, A., Swiatkowska, A., Sycamore, N., Swift, E., Symons, E., Szluha, S., Taluy, E., Tao, N., Taylor, K., Thompson, S., Thompson, M., Thomson, M., Thomson, N., Thurston, S., Toombs, D., Topping, B., Tovar-Corona, J., Ungureanu, D., Uphill, J., Urbanova, J., Jansen Van, P., Vancollie, V., Voak, P., Walker, D., Walker, M., Waller, M., Ward, G., Weatherhogg, C., Webb, N., Wells, A., Wells, E., Westwood, L., Whipp, T., Whiteley, T., Whitton, G., Whitwham, A., Widaa, S., Williams, M., Wilson, M., Wright, S., Farr, B. W., Quail, M. A., Thurston, S. A. J., Bronner, I. F., Redshaw, N. M., Lensing, S. V., Balcazar, C. E., Gallagher, M. D., Williamson, K. A., Stanton, T. D., Michelsen, M. L., Warwick-Dugdale, J., Manley, R., Farbos, A., Harrison, J. W., Sambles, C. M., Studholme, D. J., Lackenby, A., Mbisa, T., Platt, S., Miah, S., Bibby, D., Manso, C., Hubb, J., Dabrera, G., Ramsay, M., Bradshaw, D., Schaefer, U., Groves, N., Gallagher, E., Lee, D., Williams, D., Ellaby, N., Hartman, H., Manesis, N., Patel, V., Ledesma, J., Twohig, K. A., Allara, E., Pearson, C., Cheng, J. K. J., Bridgewater, H. E., Frost, L. R., Taylor-Joyce, G., Brown, P. E., Tong, L., Broos, A., Mair, D., Nichols, J., Carmichael, S. N., Smollett, K. L., Nomikou, K., Aranday-Cortes, E., Johnson, N., Nickbakhsh, S., Vamos, E. E., Hughes, M., Rainbow, L., Eccles, R., Nelson, C., Whitehead, M., Gregory, R., Gemmell, M., Wierzbicki, C., Webster, H. J., Fisher, C. L., Signell, A. W., Betancor, G., Wilson, H. D., Nebbia, G., Flaviani, F., Cerda, A. C., Merrill, T. V., Wilson, R. E., Cotic, M., Bayzid, N., Thompson, T., Acheson, E., Rushton, S., O'Brien, S., Baker, D. J., Rudder, S., Aydin, A., Sang, F., Debebe, J., Francois, S., Vasylyeva, T. I., Zamudio, M. E., Gutierrez, B., Marchbank, A., Maksimovic, J., Spellman, K., Mccluggage, K., Morgan, M., Beer, R., Afifi, S., Workman, T., Fuller, W., Bresner, C., Angyal, A., Green, L. R., Parsons, P. J., Tucker, R. M., Brown, R., Whiteley, M., Rowe, W., Siveroni, I., Le-Viet, T., Gaskin, A., Johnson, R., Sharrocks, K., Blane, E., Modis, Y., Leigh, K. E., Briggs, J. A. G., van Gils, M. J., Smith, K. G. C., Bradley, J. R., Doffinger, R., Ceron-Gutierrez, L., Barcenas-Morales, G., Pollock, D. D., Goldstein, R. A., Smielewska, A., Skittrall, J. P., Gouliouris, T., Goodfellow, I. G., Gkrania-Klotsas, E., Illingworth, C. J. R., Mccoy, L. E., Gupta, R. K., Medical Microbiology and Infection Prevention, AII - Infectious diseases, Collier, Dami A [0000-0001-5446-4423], Jahun, Aminu [0000-0002-4585-1701], Temperton, Nigel [0000-0002-7978-3815], Modis, Yorgo [0000-0002-6084-0429], Briggs, John AG [0000-0003-3990-6910], Goldstein, Richard A [0000-0001-5148-4672], Skittrall, Jordan P [0000-0002-8228-3758], Gkrania-Klotsas, Effrossyni [0000-0002-0930-8330], McCoy, Laura E [0000-0001-9503-7946], Gupta, Ravindra K [0000-0001-9751-1808], and Apollo - University of Cambridge Repository
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0301 basic medicine ,Male ,Time Factors ,viruses ,Passive ,Antibodies, Viral ,CITIID-NIHR BioResource COVID-19 Collaboration ,2.1 Biological and endogenous factors ,Viral ,Aetiology ,Neutralizing ,Lung ,Phylogeny ,neutralising antibodies ,Infectivity ,education.field_of_study ,Genome ,Multidisciplinary ,Alanine ,biology ,High-Throughput Nucleotide Sequencing ,Viral Load ,Spike Glycoprotein ,Virus Shedding ,Adenosine Monophosphate ,Aged ,Antibodies, Neutralizing ,COVID-19 ,Chronic Disease ,Genome, Viral ,Humans ,Immune Evasion ,Immune Tolerance ,Immunization, Passive ,Immunosuppression Therapy ,Mutagenesis ,Mutant Proteins ,Mutation ,SARS-CoV-2 ,Spike Glycoprotein, Coronavirus ,Evolution, Molecular ,Infectious Diseases ,Pneumonia & Influenza ,Antibody ,Infection ,Viral load ,Biotechnology ,Evolution ,General Science & Technology ,antibody escape, Convalescent plasma ,030106 microbiology ,Population ,evasion ,Antibodies ,Virus ,Article ,Vaccine Related ,resistance ,03 medical and health sciences ,Immune system ,COVID-19 Genomics UK (COG-UK) Consortium ,Biodefense ,Genetics ,Viral shedding ,education ,COVID-19 Serotherapy ,QR355 ,Prevention ,Wild type ,Molecular ,Pneumonia ,Virology ,COVID-19 Drug Treatment ,Coronavirus ,Emerging Infectious Diseases ,Good Health and Well Being ,030104 developmental biology ,biology.protein ,Immunization ,immune suppression ,mutation - Abstract
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for virus infection through the engagement of the human ACE2 protein1 and is a major antibody target. Here we show that chronic infection with SARS-CoV-2 leads to viral evolution and reduced sensitivity to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma, by generating whole-genome ultra-deep sequences for 23 time points that span 101 days and using in vitro techniques to characterize the mutations revealed by sequencing. There was little change in the overall structure of the viral population after two courses of remdesivir during the first 57 days. However, after convalescent plasma therapy, we observed large, dynamic shifts in the viral population, with the emergence of a dominant viral strain that contained a substitution (D796H) in the S2 subunit and a deletion (ΔH69/ΔV70) in the S1 N-terminal domain of the spike protein. As passively transferred serum antibodies diminished, viruses with the escape genotype were reduced in frequency, before returning during a final, unsuccessful course of convalescent plasma treatment. In vitro, the spike double mutant bearing both ΔH69/ΔV70 and D796H conferred modestly decreased sensitivity to convalescent plasma, while maintaining infectivity levels that were similar to the wild-type virus.The spike substitution mutant D796H appeared to be the main contributor to the decreased susceptibility to neutralizing antibodies, but this mutation resulted in an infectivity defect. The spike deletion mutant ΔH69/ΔV70 had a twofold higher level of infectivity than wild-type SARS-CoV-2, possibly compensating for the reduced infectivity of the D796H mutation. These data reveal strong selection on SARS-CoV-2 during convalescent plasma therapy, which is associated with the emergence of viral variants that show evidence of reduced susceptibility to neutralizing antibodies in immunosuppressed individuals.
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- 2021
14. Adjuvant Use of PlasmaJet Device During Cytoreductive Surgery for Advanced-Stage Ovarian Cancer:Results of the PlaComOv-study, a Randomized Controlled Trial in The Netherlands
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Nieuwenhuyzen-de Boer, G. M., Hofhuis, W., Reesink-Peters, N., Willemsen, S., Boere, I. A., Schoots, I. G., Piek, J. M.J., Hofman, L. N., Beltman, J. J., van Driel, W. J., Werner, H. M.J., Baalbergen, A., van Haaften-de Jong, A. M.L.D., Dorman, M., Haans, L., Nedelcu, I., Ewing-Graham, P. C., van Beekhuizen, H. J., Nieuwenhuyzen-de Boer, G. M., Hofhuis, W., Reesink-Peters, N., Willemsen, S., Boere, I. A., Schoots, I. G., Piek, J. M.J., Hofman, L. N., Beltman, J. J., van Driel, W. J., Werner, H. M.J., Baalbergen, A., van Haaften-de Jong, A. M.L.D., Dorman, M., Haans, L., Nedelcu, I., Ewing-Graham, P. C., and van Beekhuizen, H. J.
- Abstract
Objective: Standard surgical treatment of advanced-stage ovarian carcinoma with electrosurgery cannot always result in complete cytoreductive surgery (CRS), especially when many small metastases are found on the mesentery and intestinal surface. We investigated whether adjuvant use of a neutral argon plasma device can help increase the complete cytoreduction rate. Patients and Methods: 327 patients with FIGO stage IIIB–IV epithelial ovarian cancer (EOC) who underwent primary or interval CRS were randomized to either surgery with neutral argon plasma (PlasmaJet) (intervention) or without PlasmaJet (control group). The primary outcome was the percentage of complete CRS. The secondary outcomes were duration of surgery, blood loss, number of bowel resections and colostomies, hospitalization, 30-day morbidity, and quality of life (QoL). Results: Complete CRS was achieved in 119 patients (75.8%) in the intervention group and 115 patients (67.6%) in the control group (risk difference (RD) 8.2%, 95% confidence interval (CI) –0.021 to 0.181; P = 0.131). In a per-protocol analysis excluding patients with unresectable disease, complete CRS was obtained in 85.6% in the intervention group and 71.5% in the control group (RD 14.1%, 95% CI 0.042 to 0.235; P = 0.005). Patient-reported QoL at 6 months after surgery differed between groups in favor of PlasmaJet surgery (95% CI 0.455–8.350; P = 0.029). Other secondary outcomes did not differ significantly. Conclusions: Adjuvant use of PlasmaJet during CRS for advanced-stage ovarian cancer resulted in a significantly higher proportion of complete CRS in patients with resectable disease and higher QoL at 6 months after surgery. (Funded by ZonMw, Trial Register NL62035.078.17.) Trial Registration: Approved by the Medical Ethics Review Board of the Erasmus University Medical Center Rotterdam, the Netherlands, NL62035.078.17 on 20-11-2017. Recruitment started on 30-1-2018.
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- 2022
15. Observation in the MINOS far detector of the shadowing of cosmic rays by the sun and moon
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Adamson, P., Andreopoulos, C., Ayres, D.S., Backhouse, C., Barr, G., Barrett, W.L., Bishai, M., Blake, A., Bock, B., Bock, G.J., Boehnlein, D.J., Bogert, D., Bower, C., Budd, S., Cavanaugh, S., Cherdack, D., Childress, S., Choudhary, B.C., Cobb, J.H., Coelho, J.A.B., Coleman, S.J., Corwin, L., Cronin-Hennessy, D., Danko, I.Z., de Jong, J.K., Devenish, N.E., Diwan, M.V., Dorman, M., Escobar, C.O., Evans, J.J., Falk, E., Feldman, G.J., Frohne, M.V., Gallagher, H.R., Godley, A., Gomes, R.A., Goodman, M.C., Gouffon, P., Gran, R., Grant, N., Grashorn, E.W., Grzelak, K., Habig, A., Harris, D., Harris, P.G., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Huang, X., Hylen, J., Ilic, J., Irwin, G.M., Isvan, Z., Jaffe, D.E., James, C., Jensen, D., Kafka, T., Kasahara, S.M.S., Koizumi, G., Kopp, S., Kordosky, M., Krahn, Z., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P.J., Litchfield, R.P., Loiacono, L., Lucas, P., Mann, W.A., Marshak, M.L., Marshall, J.S., Mayer, N., McGowan, A.M., Mehdiyev, R., Meier, J.R., Messier, M.D., Michael, D.G., Miller, W.H., Mishra, S.R., Mitchell, J., Moore, C.D., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J.K., Newman, H.B., Nichol, R.J., Nicholls, T.C., Oliver, W.P., Orchanian, M., Paley, J., Patterson, R.B., Pawloski, G., Pearce, G.F., Peterson, E.A., Pittam, R., Plunkett, R.K., Ratchford, J., Raufer, T.M., Rebel, B., Reichenbacher, J., Rodrigues, P.A., Rosenfeld, C., Rubin, H.A., Ryabov, V.A., Sanchez, M.C., Schneps, J., Schreiner, P., Semenov, V.K., Shanahan, P., Sousa, A., Strait, M., Tagg, N., Talaga, R.L., Thomas, J., Thomson, M.A., Thron, J.L., Tinti, G., Toner, R., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Weber, A., Webb, R.C., White, C., Whitehead, L., Wojcicki, S.G., Wright, D.M., Yang, T., and Zwaska, R.
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- 2011
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16. A study into the interaction of intergranular cracking and cracking at a fastener hole
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Jones, R., Lo, M., Peng, D., Bowler, A., Dorman, M., Janardhana, M., and Iyyer, N. S.
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- 2015
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17. Genomic reconstruction of the SARS-CoV-2 epidemic in England
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Vöhringer, HS, Sanderson, T, Sinnott, M, De Maio, N, Nguyen, T, Goater, R, Schwach, F, Harrison, I, Hellewell, J, Ariani, CV, Gonçalves, S, Jackson, DK, Johnston, I, Jung, AW, Saint, C, Sillitoe, J, Suciu, M, Goldman, N, Panovska-Griffiths, J, Abnizova, I, Aigrain, L, Alderton, A, Ali, M, Allen, L, Amato, R, Anderson, R, Ariani, C, Austin-Guest, S, Bala, S, Barrett, J, Bassett, A, Battleday, K, Beal, J, Beale, M, Beaver, C, Bellany, S, Bellerby, T, Bellis, K, Berger, D, Berriman, M, Betteridge, E, Bevan, P, Binley, S, Bishop, J, Blackburn, K, Bonfield, J, Boughton, N, Bowker, S, Brendler-Spaeth, T, Bronner, I, Brooklyn, T, Buddenborg, SK, Bush, R, Caetano, C, Cagan, A, Carter, N, Cartwright, J, Monteiro, TC, Chapman, L, Chillingworth, T-J, Clapham, P, Clark, R, Clarke, A, Clarke, C, Cole, D, Cook, E, Coppola, M, Cornell, L, Cornwell, C, Corton, C, Crackett, A, Cranage, A, Craven, H, Craw, S, Crawford, M, Cutts, T, Dabrowska, M, Davies, M, Davies, R, Dawson, J, Day, C, Densem, A, Dibling, T, Dockree, C, Dodd, D, Dogga, S, Dorman, M, Dougan, G, Dougherty, M, Dove, A, Drummond, L, Drury, E, Dudek, M, Durham, J, Durrant, L, Easthope, E, Eckert, S, Ellis, P, Farr, B, Fenton, M, Ferrero, M, Flack, N, Fordham, H, Forsythe, G, Foulser, L, Francis, M, Fraser, A, Freeman, A, Galvin, A, Garcia-Casado, M, Gedny, A, Girgis, S, Glover, J, Goncalves, S, Goodwin, S, Gould, O, Gourtovaia, M, Gray, A, Gray, E, Griffiths, C, Gu, Y, Guerin, F, Hamilton, W, Hanks, H, Harrison, E, Harrott, A, Harry, E, Harvison, J, Heath, P, Hernandez-Koutoucheva, A, Hobbs, R, Holland, D, Holmes, S, Hornett, G, Hough, N, Huckle, L, Hughes-Hallet, L, Hunter, A, Inglis, S, Iqbal, S, Jackson, A, Jackson, D, James, K, Jamrozy, D, Verdejo, CJ, Jones, M, Kallepally, K, Kane, L, Kay, K, Kay, S, Keatley, J, Keith, A, King, A, Kitchin, L, Kleanthous, M, Klimekova, M, Korlevic, P, Krasheninnkova, K, Lane, G, Langford, C, Laverack, A, Law, K, Lawniczak, M, Lensing, S, Leonard, S, Letchford, L, Lewis, K, Lewis-Wade, A, Liddle, J, Lin, Q, Lindsay, S, Linsdell, S, Livett, R, Lo, S, Long, R, Lovell, J, Ludden, C, Mack, J, Maddison, M, Makunin, A, Mamun, I, Mansfield, J, Marriott, N, Martin, M, Mayho, M, McCarthy, S, McClintock, J, McGuigan, S, McHugh, S, McMinn, L, Meadows, C, Mobley, E, Moll, R, Morra, M, Morrow, L, Murie, K, Nash, S, Nathwani, C, Naydenova, P, Neaverson, A, Nelson, R, Nerou, E, Nicholson, J, Nimz, T, Noell, GG, O’Meara, S, Ohan, V, Oliver, K, Olney, C, Ormond, D, Oszlanczi, A, Palmer, S, Pang, YF, Pardubska, B, Park, N, Parmar, A, Patel, G, Patel, M, Payne, M, Peacock, S, Petersen, A, Plowman, D, Preston, T, Prestwood, L, Puethe, C, Quail, M, Rajan, D, Rajatileka, S, Rance, R, Rawlings, S, Redshaw, N, Reynolds, J, Reynolds, M, Rice, S, Richardson, M, Roberts, C, Robinson, K, Robinson, M, Robinson, D, Rogers, H, Rojo, EM, Roopra, D, Rose, M, Rudd, L, Sadri, R, Salmon, N, Saul, D, Scott, C, Seekings, P, Shirley, L, Simms, A, Sivadasan, S, Siwek, B, Sizer, D, Skeldon, K, Skelton, J, Slater-Tunstill, J, Sloper, L, Smerdon, N, Smith, C, Smith, J, Smith, K, Smith, M, Smith, S, Smith, T, Sneade, L, Soria, CD, Sousa, C, Souster, E, Sparkes, A, Spencer-Chapman, M, Squares, J, Stanley, R, Steed, C, Stickland, T, Still, I, Stratton, MR, Strickland, M, Swann, A, Swiatkowska, A, Sycamore, N, Swift, E, Symons, E, Szluha, S, Taluy, E, Tao, N, Taylor, K, Taylor, S, Thompson, S, Thompson, M, Thomson, M, Thomson, N, Thurston, S, Tonkin-Hill, G, Toombs, D, Topping, B, Tovar-Corona, J, Ungureanu, D, Uphill, J, Urbanova, J, Van Vuuren, PJ, Vancollie, V, Voak, P, Walker, D, Walker, M, Waller, M, Ward, G, Weatherhogg, C, Webb, N, Weldon, D, Wells, A, Wells, E, Westwood, L, Whipp, T, Whiteley, T, Whitton, G, Whitwham, A, Widaa, S, Williams, M, Wilson, M, Wright, S, Robson, SC, Connor, TR, Loman, NJ, Golubchik, T, Martinez Nunez, RT, Bonsall, D, Rambaut, A, Snell, LB, Corden, S, Nastouli, E, Nebbia, G, Lythgoe, K, Torok, ME, Goodfellow, IG, Prieto, JA, Saeed, K, Houlihan, C, Frampton, D, Hamilton, WL, Witney, AA, Bucca, G, Pope, CF, Moore, C, Thomson, EC, Harrison, EM, Smith, CP, Rogan, F, Beckwith, SM, Murray, A, Singleton, D, Eastick, K, Sheridan, LA, Randell, P, Jackson, LM, Fairley, DJ, Loose, MW, Watkins, J, Moses, S, Nicholls, S, Bull, M, Smith, DL, Aanensen, DM, Aggarwal, D, Shepherd, JG, Curran, MD, Parmar, S, Parker, MD, Williams, C, Glaysher, S, Underwood, AP, Bashton, M, Pacchiarini, N, Loveson, KF, Byott, M, Carabelli, AM, Templeton, KE, de Silva, TI, Wang, D, Langford, CF, Gunson, RN, Cottrell, S, O’Grady, J, Kwiatkowski, D, Lillie, PJ, Cortes, N, Moore, N, Thomas, C, Burns, PJ, Mahungu, TW, Liggett, S, Beckett, AH, Holden, MTG, Levett, LJ, Osman, H, Hassan-Ibrahim, MO, Simpson, DA, Chand, M, Gupta, RK, Darby, AC, Paterson, S, Pybus, OG, Volz, EM, de Angelis, D, Robertson, DL, Page, AJ, Bassett, AR, Wong, N, Taha, Y, Erkiert, MJ, Spencer Chapman, MH, Dewar, R, McHugh, MP, Mookerjee, S, Aplin, S, Harvey, M, Sass, T, Umpleby, H, Wheeler, H, McKenna, JP, Warne, B, Taylor, JF, Chaudhry, Y, Izuagbe, R, Jahun, AS, Young, GR, McMurray, C, McCann, CM, Nelson, A, Elliott, S, Lowe, H, Price, A, Crown, MR, Rey, S, Roy, S, Temperton, B, Shaaban, S, Hesketh, AR, Laing, KG, Monahan, IM, Heaney, J, Pelosi, E, Silviera, S, Wilson-Davies, E, Fryer, H, Adams, H, du Plessis, L, Johnson, R, Harvey, WT, Hughes, J, Orton, RJ, Spurgin, LG, Bourgeois, Y, Ruis, C, O’Toole, Á, Fraser, C, Edgeworth, J, Breuer, J, Michell, SL, Todd, JA, John, M, Buck, D, Gajee, K, Kay, GL, Peacock, SJ, Heyburn, D, Kitchman, K, McNally, A, Pritchard, DT, Dervisevic, S, Muir, P, Robinson, E, Vipond, BB, Ramadan, NA, Jeanes, C, Catalan, J, Jones, N, da Silva Filipe, A, Fuchs, M, Miskelly, J, Jeffries, AR, Park, NR, Ash, A, Koshy, C, Barrow, M, Buchan, SL, Mantzouratou, A, Clark, G, Holmes, CW, Campbell, S, Davis, T, Tan, NK, Brown, JR, Harris, KA, Kidd, SP, Grant, PR, Xu-McCrae, L, Cox, A, Madona, P, Pond, M, Randell, PA, Withell, KT, Graham, C, Denton-Smith, R, Swindells, E, Turnbull, R, Sloan, TJ, Bosworth, A, Hutchings, S, Pymont, HM, Casey, A, Ratcliffe, L, Jones, CR, Knight, BA, Haque, T, Hart, J, Irish-Tavares, D, Witele, E, Mower, C, Watson, LK, Collins, J, Eltringham, G, Crudgington, D, Macklin, B, Iturriza-Gomara, M, Lucaci, AO, McClure, PC, Carlile, M, Holmes, N, Storey, N, Rooke, S, Yebra, G, Craine, N, Perry, M, Alikhan, N-F, Bridgett, S, Cook, KF, Fearn, C, Goudarzi, S, Lyons, RA, Williams, T, Haldenby, ST, Davies, RM, Batra, R, Blane, B, Spyer, MJ, Smith, P, Yavus, M, Williams, RJ, Mahanama, AIK, Samaraweera, B, Girgis, ST, Hansford, SE, Green, A, Bellis, KL, Dorman, MJ, Quick, J, Poplawski, R, Reynolds, N, Mack, A, Morriss, A, Whalley, T, Patel, B, Georgana, I, Hosmillo, M, Pinckert, ML, Stockton, J, Henderson, JH, Hollis, A, Stanley, W, Yew, WC, Myers, R, Thornton, A, Adams, A, Annett, T, Asad, H, Birchley, A, Coombes, J, Evans, JM, Fina, L, Gatica-Wilcox, B, Gilbert, L, Graham, L, Hey, J, Hilvers, E, Jones, S, Jones, H, Kumziene-Summerhayes, S, McKerr, C, Powell, J, Pugh, G, Trotter, AJ, Williams, CA, Kermack, LM, Foulkes, BH, Gallis, M, Hornsby, HR, Louka, SF, Pohare, M, Wolverson, P, Zhang, P, MacIntyre-Cockett, G, Trebes, A, Moll, RJ, Ferguson, L, Goldstein, EJ, Maclean, A, Tomb, R, Starinskij, I, Thomson, L, Southgate, J, Kraemer, MUG, Raghwani, J, Zarebski, AE, Boyd, O, Geidelberg, L, Illingworth, CJ, Jackson, C, Pascall, D, Vattipally, S, Freeman, TM, Hsu, SN, Lindsey, BB, Tovar-Corona, JM, Cox, M, Abudahab, K, Menegazzo, M, Taylor, BEW, Yeats, CA, Mukaddas, A, Wright, DW, de Oliveira Martins, L, Colquhoun, R, Hill, V, Jackson, B, McCrone, JT, Medd, N, Scher, E, Keatley, J-P, Curran, T, Morgan, S, Maxwell, P, Eldirdiri, S, Kenyon, A, Holmes, AH, Price, JR, Wyatt, T, Mather, AE, Skvortsov, T, Hartley, JA, Guest, M, Kitchen, C, Merrick, I, Munn, R, Bertolusso, B, Lynch, J, Vernet, G, Kirk, S, Wastnedge, E, Idle, G, Bradley, DT, Poyner, J, Mori, M, Jones, O, Wright, V, Brooks, E, Churcher, CM, Fragakis, M, Galai, K, Jermy, A, Judges, S, McManus, GM, Smith, KS, Westwick, E, Attwood, SW, Bolt, F, Davies, A, De Lacy, E, Downing, F, Edwards, S, Meadows, L, Jeremiah, S, Smith, N, Charalampous, T, Patel, A, Berry, L, Boswell, T, Fleming, VM, Howson-Wells, HC, Joseph, A, Khakh, M, Lister, MM, Bird, PW, Fallon, K, Helmer, T, McMurray, CL, Odedra, M, Shaw, J, Tang, JW, Willford, NJ, Blakey, V, Raviprakash, V, Sheriff, N, Williams, L-A, Feltwell, T, Bedford, L, Cargill, JS, Hughes, W, Moore, J, Stonehouse, S, Atkinson, L, Lee, JCD, Shah, D, Alcolea, A, Ohemeng-Kumi, N, Ramble, J, Sehmi, J, Williams, R, Chatterton, W, Pusok, M, Everson, W, Castigador, A, Macnaughton, E, El Bouzidi, K, Lampejo, T, Sudhanva, M, Breen, C, Sluga, G, Ahmad, SSY, George, RP, Machin, NW, Binns, D, James, V, Blacow, R, Coupland, L, Smith, L, Barton, E, Padgett, D, Scott, G, Cross, A, Mirfenderesky, M, Greenaway, J, Cole, K, Clarke, P, Duckworth, N, Walsh, S, Bicknell, K, Impey, R, Wyllie, S, Hopes, R, Bishop, C, Chalker, V, Gifford, L, Molnar, Z, Auckland, C, Evans, C, Johnson, K, Partridge, DG, Raza, M, Baker, P, Bonner, S, Essex, S, Murray, LJ, Lawton, AI, Burton-Fanning, S, Payne, BAI, Waugh, S, Gomes, AN, Kimuli, M, Murray, DR, Ashfield, P, Dobie, D, Ashford, F, Best, A, Crawford, L, Cumley, N, Mayhew, M, Megram, O, Mirza, J, Moles-Garcia, E, Percival, B, Ensell, L, Lowe, HL, Maftei, L, Mondani, M, Chaloner, NJ, Cogger, BJ, Easton, LJ, Huckson, H, Lewis, J, Lowdon, S, Malone, CS, Munemo, F, Mutingwende, M, Nicodemi, R, Podplomyk, O, Somassa, T, Beggs, A, Richter, A, Cormie, C, Dias, J, Forrest, S, Higginson, EE, Maes, M, Young, J, Davidson, RK, Jackson, KA, Turtle, L, Keeley, AJ, Ball, J, Byaruhanga, T, Chappell, JG, Dey, J, Hill, JD, Park, EJ, Fanaie, A, Hilson, RA, Yaze, G, Afifi, S, Beer, R, Maksimovic, J, Masters, KM, Spellman, K, Bresner, C, Fuller, W, Marchbank, A, Workman, T, Shelest, E, Debebe, J, Sang, F, Zamudio, ME, Francois, S, Gutierrez, B, Vasylyeva, TI, Flaviani, F, Ragonnet-Cronin, M, Smollett, KL, Broos, A, Mair, D, Nichols, J, Nomikou, K, Tong, L, Tsatsani, I, O’Brien, S, Rushton, S, Sanderson, R, Perkins, J, Cotton, S, Gallagher, A, Allara, E, Pearson, C, Bibby, D, Dabrera, G, Ellaby, N, Gallagher, E, Hubb, J, Lackenby, A, Lee, D, Manesis, N, Mbisa, T, Platt, S, Twohig, KA, Morgan, M, Aydin, A, Baker, DJ, Foster-Nyarko, E, Prosolek, SJ, Rudder, S, Baxter, C, Carvalho, SF, Lavin, D, Mariappan, A, Radulescu, C, Singh, A, Tang, M, Morcrette, H, Bayzid, N, Cotic, M, Balcazar, CE, Gallagher, MD, Maloney, D, Stanton, TD, Williamson, KA, Manley, R, Michelsen, ML, Sambles, CM, Studholme, DJ, Warwick-Dugdale, J, Eccles, R, Gemmell, M, Gregory, R, Hughes, M, Nelson, C, Rainbow, L, Vamos, EE, Webster, HJ, Whitehead, M, Wierzbicki, C, Angyal, A, Green, LR, Whiteley, M, Bronner, IF, Farr, BW, Lensing, SV, McCarthy, SA, Quail, MA, Redshaw, NM, Thurston, SAJ, Rowe, W, Gaskin, A, Le-Viet, T, Birney, E, Volz, E, Funk, S, Martincorena, I, Barrett, JC, and Gerstung, M
- Abstract
The evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus leads to new variants that warrant timely epidemiological characterization. Here we use the dense genomic surveillance data generated by the COVID-19 Genomics UK Consortium to reconstruct the dynamics of 71 different lineages in each of 315 English local authorities between September 2020 and June 2021. This analysis reveals a series of subepidemics that peaked in early autumn 2020, followed by a jump in transmissibility of the B.1.1.7/Alpha lineage. The Alpha variant grew when other lineages declined during the second national lockdown and regionally tiered restrictions between November and December 2020. A third more stringent national lockdown suppressed the Alpha variant and eliminated nearly all other lineages in early 2021. Yet a series of variants (most of which contained the spike E484K mutation) defied these trends and persisted at moderately increasing proportions. However, by accounting for sustained introductions, we found that the transmissibility of these variants is unlikely to have exceeded the transmissibility of the Alpha variant. Finally, B.1.617.2/Delta was repeatedly introduced in England and grew rapidly in early summer 2021, constituting approximately 98% of sampled SARS-CoV-2 genomes on 26 June 2021.
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- 2021
18. The Changing Face of Maritime Power
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A. Dorman, M. Lawrence Smith, M. Uttley, Mike Lawrence Smith, A. Dorman, M. Lawrence Smith, M. Uttley, Mike Lawrence Smith
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- 1999
19. 280 Improvement of complete cytoreduction for advanced-stage ovarian cancer with adjuvant use of the PlasmaJet Device. Results of a RCT
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Nieuwenhuyzen-de Boer, G, primary, Hofhuis, W, additional, Reesink-Peters, N, additional, Willemsen, S, additional, Boere, IA, additional, Schoots, IG, additional, Piek, J, additional, Hofman, L, additional, Beltman, J, additional, Van Driel, WJ, additional, Werner, HMJ, additional, Dorman, M, additional, Haans, L, additional, Baalbergen, A, additional, Jong, AMLDVan Haaften-de, additional, Nedelcu, I, additional, Ewing-Graham, PC, additional, and Van Beekhuizen, HJ, additional
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- 2021
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20. 102. Pottery Among the Wangoni and Wandendehule, Southern Tanganyika
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Dorman, M. H.
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- 1938
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21. The Changing Face of Military Power: Joint Warfare in an Expeditionary Era
- Author
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A. Dorman, M. Smith, M. Uttley
- Published
- 2002
22. The magnetized steel and scintillator calorimeters of the MINOS experiment
- Author
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Michael, D.G., Adamson, P., Alexopoulos, T., Allison, W.W.M., Alner, G.J., Anderson, K., Andreopoulos, C., Andrews, M., Andrews, R., Arroyo, C., Avvakumov, S., Ayres, D.S., Baller, B., Barish, B., Barker, M.A., Barnes, P.D., Jr., Barr, G., Barrett, W.L., Beall, E., Bechtol, K., Becker, B.R., Belias, A., Bergfeld, T., Bernstein, R.H., Bhattacharya, D., Bishai, M., Blake, A., Bocean, V., Bock, B., Bock, G.J., Boehm, J., Boehnlein, D.J., Bogert, D., Border, P.M., Bower, C., Boyd, S., Buckley-Geer, E., Byon-Wagner, A., Cabrera, A., Chapman, J.D., Chase, T.R., Chernichenko, S.K., Childress, S., Choudhary, B.C., Cobb, J.H., Coleman, S.J., Cossairt, J.D., Courant, H., Crane, D.A., Culling, A.J., Damiani, D., Dawson, J.W., de Jong, J.K., DeMuth, D.M., De Santo, A., Dierckxsens, M., Diwan, M.V., Dorman, M., Drake, G., Ducar, R., Durkin, T., Erwin, A.R., Escobar, C.O., Evans, J.J., Fackler, O.D., Falk Harris, E., Feldman, G.J., Felt, N., Fields, T.H., Ford, R., Frohne, M.V., Gallagher, H.R., Gebhard, M., Godley, A., Gogos, J., Goodman, M.C., Gornushkin, Yu., Gouffon, P., Grashorn, E.W., Grossman, N., Grudzinski, J.J., Grzelak, K., Guarino, V., Habig, A., Halsall, R., Hanson, J., Harris, D., Harris, P.G., Hartnell, J., Hartouni, E.P., Hatcher, R., Heller, K., Hill, N., Ho, Y., Howcroft, C., Hylen, J., Ignatenko, M., Indurthy, D., Irwin, G.M., James, C., Jenner, L., Jensen, D., Joffe-Minor, T., Kafka, T., Kang, H.J., Kasahara, S.M.S., Kilmer, J., Kim, H., Kim, M.S., Koizumi, G., Kopp, S., Kordosky, M., Koskinen, D.J., Kostin, M., Kotelnikov, S.K., Krakauer, D.A., Kumaratunga, S., Ladran, A.S., Lang, K., Laughton, C., Lebedev, A., Lee, R., Lee, W.Y., Libkind, M.A., Liu, J., Litchfield, P.J., Litchfield, R.P., Longley, N.P., Lucas, P., Luebke, W., Madani, S., Maher, E., Makeev, V., Mann, W.A., Marchionni, A., Marino, A.D., Marshak, M.L., Marshall, J.S., McDonald, J., McGowan, A.M., Meier, J.R., Merzon, G.I., Messier, M.D., Milburn, R.H., Miller, J.L., Miller, W.H., Mishra, S.R., Miyagawa, P.S., Moore, C.D., Morfín, J., Morse, R., Mualem, L., Mufson, S., Murgia, S., Murtagh, M.J., Musser, J., Naples, D., Nelson, C., Nelson, J.K., Newman, H.B., Nezrick, F., Nichol, R.J., Nicholls, T.C., Ochoa-Ricoux, J.P., Oliver, J., Oliver, W.P., Onuchin, V.A., Osiecki, T., Ospanov, R., Paley, J., Paolone, V., Para, A., Patzak, T., Pavlović, Ž., Pearce, G.F., Pearson, N., Peck, C.W., Perry, C., Peterson, E.A., Petyt, D.A., Ping, H., Piteira, R., Pla-Dalmau, A., Plunkett, R.K., Price, L.E., Proga, M., Pushka, D.R., Rahman, D., Rameika, R.A., Raufer, T.M., Read, A.L., Rebel, B., Reyna, D.E., Rosenfeld, C., Rubin, H.A., Ruddick, K., Ryabov, V.A., Saakyan, R., Sanchez, M.C., Saoulidou, N., Schneps, J., Schoessow, P.V., Schreiner, P., Schwienhorst, R., Semenov, V.K., Seun, S.-M., Shanahan, P., Shield, P.D., Shivane, R., Smart, W., Smirnitsky, V., Smith, C., Smith, P.N., Sousa, A., Speakman, B., Stamoulis, P., Stefanik, A., Sullivan, P., Swan, J.M., Symes, P.A., Tagg, N., Talaga, R.L., Terekhov, A., Tetteh-Lartey, E., Thomas, J., Thompson, J., Thomson, M.A., Thron, J.L., Trendler, R., Trevor, J., Trostin, I., Tsarev, V.A., Tzanakos, G., Urheim, J., Vahle, P., Vakili, M., Vaziri, K., Velissaris, C., Verebryusov, V., Viren, B., Wai, L., Ward, C.P., Ward, D.R., Watabe, M., Weber, A., Webb, R.C., Wehmann, A., West, N., White, C., White, R.F., Wojcicki, S.G., Wright, D.M., Wu, Q.K., Yan, W.G., Yang, T., Yumiceva, F.X., Yun, J.C., Zheng, H., Zois, M., and Zwaska, R.
- Published
- 2008
- Full Text
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23. Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies
- Author
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Collier, D. A., De Marco, A., Ferreira, I. A. T. M., Meng, B., Datir, R. P., Walls, A. C., Kemp, S. A., Bassi, J., Pinto, D., Silacci-Fregni, C., Bianchi, S., Tortorici, M. A., Bowen, J., Culap, K., Jaconi, S., Cameroni, E., Snell, G., Pizzuto, M. S., Pellanda, A. F., Garzoni, C., Riva, A., Baker, S., Dougan, G., Hess, C., Kingston, N., Lehner, P. J., Lyons, P. A., Matheson, N. J., Owehand, W. H., Saunders, C., Summers, C., Thaventhiran, J. E. D., Toshner, M., Weekes, M. P., Bucke, A., Calder, J., Canna, L., Domingo, J., Elmer, A., Fuller, S., Harris, J., Hewitt, S., Kennet, J., Jose, S., Kourampa, J., Meadows, A., O'Brien, C., Price, J., Publico, C., Rastall, R., Ribeiro, C., Rowlands, J., Ruffolo, V., Tordesillas, H., Bullman, B., Dunmore, B. J., Fawke, S., Graf, S., Hodgson, J., Huang, C., Hunter, K., Jones, E., Legchenko, E., Matara, C., Martin, J., Mescia, F., O'Donnell, C., Pointon, L., Pond, N., Shih, J., Sutcliffe, R., Tilly, T., Treacy, C., Tong, Z., Wood, J., Wylot, M., Bergamaschi, L., Betancourt, A., Bower, G., Cossetti, C., De Sa, A., Epping, M., Grenfell, R., Hinch, A., Huhn, O., Jackson, S., Jarvis, I., Lewis, D., Marsden, J., Nice, F., Okecha, G., Omarjee, O., Perera, M., Richoz, N., Romashova, V., Yarkoni, N. S., Sharma, R., Stefanucci, L., Stephens, J., Strezlecki, M., Turner, L., De Bie, E. M. D. D., Bunclark, K., Josipovic, M., Mackay, M., Rossi, S., Selvan, M., Spencer, S., Yong, C., Ansaripour, A., Michael, A., Mwaura, L., Patterson, C., Polwarth, G., Polgarova, P., di Stefano, G., Fahey, C., Michel, R., Bong, S. -H., Coudert, J. D., Holmes, E., Allison, J., Butcher, H., Caputo, D., Clapham-Riley, D., Dewhurst, E., Furlong, A., Graves, B., Gray, J., Ivers, T., Kasanicki, M., Le Gresley, E., Linger, R., Meloy, S., Muldoon, F., Ovington, N., Papadia, S., Phelan, I., Stark, H., Stirrups, K. E., Townsend, P., Walker, N., Webster, J., Mccoy, L. E., Smith, K. G. C., Bradley, J. R., Temperton, N., Ceron-Gutierrez, L., Barcenas-Morales, G., Robson, S. C., Loman, N. J., Connor, T. R., Golubchik, T., Martinez Nunez, R. T., Ludden, C., Corden, S., Johnston, I., Bonsall, D., Smith, C. P., Awan, A. R., Bucca, G., Torok, M. E., Saeed, K., Prieto, J. A., Jackson, D. K., Hamilton, W. L., Snell, L. B., Moore, C., Harrison, E. M., Goncalves, S., Fairley, D. J., Loose, M. W., Watkins, J., Livett, R., Moses, S., Amato, R., Nicholls, S., Bull, M., Smith, D. L., Barrett, J., Aanensen, D. M., Curran, M. D., Parmar, S., Aggarwal, D., Shepherd, J. G., Parker, M. D., Glaysher, S., Bashton, M., Underwood, A. P., Pacchiarini, N., Loveson, K. F., Carabelli, A. M., Templeton, K. E., Langford, C. F., Sillitoe, J., de Silva, T. I., Wang, D., Kwiatkowski, D., Rambaut, A., O'Grady, J., Cottrell, S., Holden, M. T. G., Thomson, E. C., Osman, H., Andersson, M., Chauhan, A. J., Hassan-Ibrahim, M. O., Lawniczak, M., Alderton, A., Chand, M., Constantinidou, C., Unnikrishnan, M., Darby, A. C., Hiscox, J. A., Paterson, S., Martincorena, I., Robertson, D. L., Volz, E. M., Page, A. J., Pybus, O. G., Bassett, A. R., Ariani, C. V., Spencer Chapman, M. H., K. K., Li, Shah, R. N., Jesudason, N. G., Taha, Y., Mchugh, M. P., Dewar, R., Jahun, A. S., Mcmurray, C., Pandey, S., Mckenna, J. P., Nelson, A., Young, G. R., Mccann, C. M., Elliott, S., Lowe, H., Temperton, B., Roy, S., Price, A., Rey, S., Wyles, M., Rooke, S., Shaaban, S., de Cesare, M., Letchford, L., Silveira, S., Pelosi, E., Wilson-Davies, E., Hosmillo, M., O'Toole, A., Hesketh, A. R., Stark, R., du Plessis, L., Ruis, C., Adams, H., Bourgeois, Y., Michell, S. L., Gramatopoulos, D., Edgeworth, J., Breuer, J., Todd, J. A., Fraser, C., Buck, D., John, M., Kay, G. L., Palmer, S., Peacock, S. J., Heyburn, D., Weldon, D., Robinson, E., Mcnally, A., Muir, P., Vipond, I. B., Boyes, J., Sivaprakasam, V., Salluja, T., Dervisevic, S., Meader, E. J., Park, N. R., Oliver, K., Jeffries, A. R., Ott, S., da Silva Filipe, A., Simpson, D. A., Williams, C., Masoli, J. A. H., Knight, B. A., Jones, C. R., Koshy, C., Ash, A., Casey, A., Bosworth, A., Ratcliffe, L., Xu-McCrae, L., Pymont, H. M., Hutchings, S., Berry, L., Jones, K., Halstead, F., Davis, T., Holmes, C., Iturriza-Gomara, M., Lucaci, A. O., Randell, P. A., Cox, A., Madona, P., Harris, K. A., Brown, J. R., Mahungu, T. W., Irish-Tavares, D., Haque, T., Hart, J., Witele, E., Fenton, M. L., Liggett, S., Graham, C., Swindells, E., Collins, J., Eltringham, G., Campbell, S., Mcclure, P. C., Clark, G., Sloan, T. J., Jones, C., Lynch, J., Warne, B., Leonard, S., Durham, J., Williams, T., Haldenby, S. T., Storey, N., Alikhan, N. -F., Holmes, N., Carlile, M., Perry, M., Craine, N., Lyons, R. A., Beckett, A. H., Goudarzi, S., Fearn, C., Cook, K., Dent, H., Paul, H., Davies, R., Blane, B., Girgis, S. T., Beale, M. A., Bellis, K. L., Dorman, M. J., Drury, E., Kane, L., Kay, S., Mcguigan, S., Nelson, R., Prestwood, L., Rajatileka, S., Batra, R., Williams, R. J., Kristiansen, M., Green, A., Justice, A., Mahanama, A. I. K., Samaraweera, B., Hadjirin, N. F., Quick, J., Poplawski, R., Kermack, L. M., Reynolds, N., Hall, G., Chaudhry, Y., Pinckert, M. L., Georgana, I., Moll, R. J., Thornton, A., Myers, R., Stockton, J., Williams, C. A., Yew, W. C., Trotter, A. J., Trebes, A., MacIntyre-Cockett, G., Birchley, A., Adams, A., Plimmer, A., Gatica-Wilcox, B., Mckerr, C., Hilvers, E., Jones, H., Asad, H., Coombes, J., Evans, J. M., Fina, L., Gilbert, L., Graham, L., Cronin, M., Kumziene-Summerhayes, S., Taylor, S., Jones, S., Groves, D. C., Zhang, P., Gallis, M., Louka, S. F., Starinskij, I., Jackson, C., Gourtovaia, M., Tonkin-Hill, G., Lewis, K., Tovar-Corona, J. M., James, K., Baxter, L., Alam, M. T., Orton, R. J., Hughes, J., Vattipally, S., Ragonnet-Cronin, M., Nascimento, F. F., Jorgensen, D., Boyd, O., Geidelberg, L., Zarebski, A. E., Raghwani, J., Kraemer, M. U. G., Southgate, J., Lindsey, B. B., Freeman, T. M., Keatley, J. -P., Singer, J. B., de Oliveira Martins, L., Yeats, C. A., Abudahab, K., Taylor, B. E. W., Menegazzo, M., Danesh, J., Hogsden, W., Eldirdiri, S., Kenyon, A., Mason, J., Robinson, T. I., Holmes, A., Hartley, J. A., Curran, T., Mather, A. E., Shankar, G., Jones, R., Howe, R., Morgan, S., Wastenge, E., Chapman, M. R., Mookerjee, S., Stanley, R., Smith, W., Peto, T., Eyre, D., Crook, D., Vernet, G., Kitchen, C., Gulliver, H., Merrick, I., Guest, M., Munn, R., Bradley, D. T., Wyatt, T., Beaver, C., Foulser, L., Churcher, C. M., Brooks, E., Smith, K. S., Galai, K., Mcmanus, G. M., Bolt, F., Coll, F., Meadows, L., Attwood, S. W., Davies, A., De Lacy, E., Downing, F., Edwards, S., Scarlett, G. P., Jeremiah, S., Smith, N., Leek, D., Sridhar, S., Forrest, S., Cormie, C., Gill, H. K., Dias, J., Higginson, E. E., Maes, M., Young, J., Wantoch, M., Jamrozy, D., Lo, S., Patel, M., Hill, V., Bewshea, C. M., Ellard, S., Auckland, C., Harrison, I., Bishop, C., Chalker, V., Richter, A., Beggs, A., Best, A., Percival, B., Mirza, J., Megram, O., Mayhew, M., Crawford, L., Ashcroft, F., Moles-Garcia, E., Cumley, N., Hopes, R., Asamaphan, P., Niebel, M. O., Gunson, R. N., Bradley, A., Maclean, A., Mollett, G., Blacow, R., Bird, P., Helmer, T., Fallon, K., Tang, J., Hale, A. D., Macfarlane-Smith, L. R., Harper, K. L., Carden, H., Machin, N. W., Jackson, K. A., Ahmad, S. S. Y., George, R. P., Turtle, L., O'Toole, E., Watts, J., Breen, C., Cowell, A., Alcolea-Medina, A., Charalampous, T., Patel, A., Levett, L. J., Heaney, J., Rowan, A., Taylor, G. P., Shah, D., Atkinson, L., Lee, J. C. D., Westhorpe, A. P., Jannoo, R., Lowe, H. L., Karamani, A., Ensell, L., Chatterton, W., Pusok, M., Dadrah, A., Symmonds, A., Sluga, G., Molnar, Z., Baker, P., Bonner, S., Essex, S., Barton, E., Padgett, D., Scott, G., Greenaway, J., Payne, B. A. I., Burton-Fanning, S., Waugh, S., Raviprakash, V., Sheriff, N., Blakey, V., Williams, L. -A., Moore, J., Stonehouse, S., Smith, L., Davidson, R. K., Bedford, L., Coupland, L., Wright, V., Chappell, J. G., Tsoleridis, T., Ball, J., Khakh, M., Fleming, V. M., Lister, M. M., Howson-Wells, H. C., Boswell, T., Joseph, A., Willingham, I., Duckworth, N., Walsh, S., Wise, E., Moore, N., Mori, M., Cortes, N., Kidd, S., Williams, R., Gifford, L., Bicknell, K., Wyllie, S., Lloyd, A., Impey, R., Malone, C. S., Cogger, B. J., Levene, N., Monaghan, L., Keeley, A. J., Partridge, D. G., Raza, M., Evans, C., Johnson, K., Betteridge, E., Farr, B. W., Goodwin, S., Quail, M. A., Scott, C., Shirley, L., Thurston, S. A. J., Rajan, D., Bronner, I. F., Aigrain, L., Redshaw, N. M., Lensing, S. V., Mccarthy, S., Makunin, A., Balcazar, C. E., Gallagher, M. D., Williamson, K. A., Stanton, T. D., Michelsen, M. L., Warwick-Dugdale, J., Manley, R., Farbos, A., Harrison, J. W., Sambles, C. M., Studholme, D. J., Lackenby, A., Mbisa, T., Platt, S., Miah, S., Bibby, D., Manso, C., Hubb, J., Dabrera, G., Ramsay, M., Bradshaw, D., Schaefer, U., Groves, N., Gallagher, E., Lee, D., Williams, D., Ellaby, N., Hartman, H., Manesis, N., Patel, V., Ledesma, J., Twohig, K. A., Allara, E., Pearson, C., Cheng, J. K. J., Bridgewater, H. E., Frost, L. R., Taylor-Joyce, G., Brown, P. E., Tong, L., Broos, A., Mair, D., Nichols, J., Carmichael, S. N., Smollett, K. L., Nomikou, K., Aranday-Cortes, E., Johnson, N., Nickbakhsh, S., Vamos, E. E., Hughes, M., Rainbow, L., Eccles, R., Nelson, C., Whitehead, M., Gregory, R., Gemmell, M., Wierzbicki, C., Webster, H. J., Fisher, C. L., Signell, A. W., Betancor, G., Wilson, H. D., Nebbia, G., Flaviani, F., Cerda, A. C., Merrill, T. V., Wilson, R. E., Cotic, M., Bayzid, N., Thompson, T., Acheson, E., Rushton, S., O'Brien, S., Baker, D. J., Rudder, S., Aydin, A., Sang, F., Debebe, J., Francois, S., Vasylyeva, T. I., Zamudio, M. E., Gutierrez, B., Marchbank, A., Maksimovic, J., Spellman, K., Mccluggage, K., Morgan, M., Beer, R., Afifi, S., Workman, T., Fuller, W., Bresner, C., Angyal, A., Green, L. R., Parsons, P. J., Tucker, R. M., Brown, R., Whiteley, M., Bonfield, J., Puethe, C., Whitwham, A., Liddle, J., Rowe, W., Siveroni, I., Le-Viet, T., Gaskin, A., Johnson, R., Abnizova, I., Ali, M., Allen, L., Anderson, R., Ariani, C., Austin-Guest, S., Bala, S., Bassett, A., Battleday, K., Beal, J., Beale, M., Bellany, S., Bellerby, T., Bellis, K., Berger, D., Berriman, M., Bevan, P., Binley, S., Bishop, J., Blackburn, K., Boughton, N., Bowker, S., Brendler-Spaeth, T., Bronner, I., Brooklyn, T., Buddenborg, S. K., Bush, R., Caetano, C., Cagan, A., Carter, N., Cartwright, J., Monteiro, T. C., Chapman, L., Chillingworth, T. -J., Clapham, P., Clark, R., Clarke, A., Clarke, C., Cole, D., Cook, E., Coppola, M., Cornell, L., Cornwell, C., Corton, C., Crackett, A., Cranage, A., Craven, H., Craw, S., Crawford, M., Cutts, T., Dabrowska, M., Davies, M., Dawson, J., Day, C., Densem, A., Dibling, T., Dockree, C., Dodd, D., Dogga, S., Dougherty, M., Dove, A., Drummond, L., Dudek, M., Durrant, L., Easthope, E., Eckert, S., Ellis, P., Farr, B., Fenton, M., Ferrero, M., Flack, N., Fordham, H., Forsythe, G., Francis, M., Fraser, A., Freeman, A., Galvin, A., Garcia-Casado, M., Gedny, A., Girgis, S., Glover, J., Gould, O., Gray, A., Gray, E., Griffiths, C., Gu, Y., Guerin, F., Hamilton, W., Hanks, H., Harrison, E., Harrott, A., Harry, E., Harvison, J., Heath, P., Hernandez-Koutoucheva, A., Hobbs, R., Holland, D., Holmes, S., Hornett, G., Hough, N., Huckle, L., Hughes-Hallet, L., Hunter, A., Inglis, S., Iqbal, S., Jackson, A., Jackson, D., Verdejo, C. J., Jones, M., Kallepally, K., Kay, K., Keatley, J., Keith, A., King, A., Kitchin, L., Kleanthous, M., Klimekova, M., Korlevic, P., Krasheninnkova, K., Lane, G., Langford, C., Laverack, A., Law, K., Lensing, S., Lewis-Wade, A., Lin, Q., Lindsay, S., Linsdell, S., Long, R., Lovell, J., Mack, J., Maddison, M., Mamun, I., Mansfield, J., Marriott, N., Martin, M., Mayho, M., Mcclintock, J., Mchugh, S., Mcminn, L., Meadows, C., Mobley, E., Moll, R., Morra, M., Morrow, L., Murie, K., Nash, S., Nathwani, C., Naydenova, P., Neaverson, A., Nerou, E., Nicholson, J., Nimz, T., Noell, G. G., O'Meara, S., Ohan, V., Olney, C., Ormond, D., Oszlanczi, A., Pang, Y. F., Pardubska, B., Park, N., Parmar, A., Patel, G., Payne, M., Peacock, S., Petersen, A., Plowman, D., Preston, T., Quail, M., Rance, R., Rawlings, S., Redshaw, N., Reynolds, J., Reynolds, M., Rice, S., Richardson, M., Roberts, C., Robinson, K., Robinson, M., Robinson, D., Rogers, H., Rojo, E. M., Roopra, D., Rose, M., Rudd, L., Sadri, R., Salmon, N., Saul, D., Schwach, F., Seekings, P., Simms, A., Sinnott, M., Sivadasan, S., Siwek, B., Sizer, D., Skeldon, K., Skelton, J., Slater-Tunstill, J., Sloper, L., Smerdon, N., Smith, C., Smith, J., Smith, K., Smith, M., Smith, S., Smith, T., Sneade, L., Soria, C. D., Sousa, C., Souster, E., Sparkes, A., Spencer-Chapman, M., Squares, J., Steed, C., Stickland, T., Still, I., Stratton, M., Strickland, M., Swann, A., Swiatkowska, A., Sycamore, N., Swift, E., Symons, E., Szluha, S., Taluy, E., Tao, N., Taylor, K., Thompson, S., Thompson, M., Thomson, M., Thomson, N., Thurston, S., Toombs, D., Topping, B., Tovar-Corona, J., Ungureanu, D., Uphill, J., Urbanova, J., Van, P. J., Vancollie, V., Voak, P., Walker, D., Walker, M., Waller, M., Ward, G., Weatherhogg, C., Webb, N., Wells, A., Wells, E., Westwood, L., Whipp, T., Whiteley, T., Whitton, G., Widaa, S., Williams, M., Wilson, M., Wright, S., Harvey, W., Virgin, H. W., Lanzavecchia, A., Piccoli, L., Doffinger, R., Wills, M., Veesler, D., Corti, D., and Gupta, R. K.
- Subjects
0301 basic medicine ,Male ,Models, Molecular ,Passive ,Antibodies, Viral ,Neutralization ,0302 clinical medicine ,Models ,Monoclonal ,80 and over ,Viral ,Neutralizing antibody ,Neutralizing ,Aged, 80 and over ,Vaccines ,Vaccines, Synthetic ,Multidisciplinary ,biology ,Antibodies, Monoclonal ,C500 ,Middle Aged ,C700 ,Spike Glycoprotein ,Vaccination ,Spike Glycoprotein, Coronavirus ,Female ,Angiotensin-Converting Enzyme 2 ,Antibody ,Aged ,Antibodies, Neutralizing ,COVID-19 ,COVID-19 Vaccines ,HEK293 Cells ,Humans ,Immune Evasion ,Immunization, Passive ,Mutation ,Neutralization Tests ,SARS-CoV-2 ,medicine.drug_class ,B100 ,Monoclonal antibody ,Antibodies ,Virus ,03 medical and health sciences ,Immune system ,medicine ,COVID-19 Serotherapy ,QR355 ,Synthetic ,Molecular ,Virology ,Coronavirus ,030104 developmental biology ,Immunization ,biology.protein ,030217 neurology & neurosurgery - Abstract
Transmission of SARS-CoV-2 is uncontrolled in many parts of the world; control is compounded in some areas by the higher transmission potential of the B.1.1.7 variant1, which has now been reported in 94 countries. It is unclear whether the response of the virus to vaccines against SARS-CoV-2 on the basis of the prototypic strain will be affected by the mutations found in B.1.1.7. Here we assess the immune responses of individuals after vaccination with the mRNA-based vaccine BNT162b22. We measured neutralizing antibody responses after the first and second immunizations using pseudoviruses that expressed the wild-type spike protein or a mutated spike protein that contained the eight amino acid changes found in the B.1.1.7 variant. The sera from individuals who received the vaccine exhibited a broad range of neutralizing titres against the wild-type pseudoviruses that were modestly reduced against the B.1.1.7 variant. This reduction was also evident in sera from some patients who had recovered from COVID-19. Decreased neutralization of the B.1.1.7 variant was also observed for monoclonal antibodies that target the N-terminal domain (9 out of 10) and the receptor-binding motif (5 out of 31), but not for monoclonal antibodies that recognize the receptor-binding domain that bind outside the receptor-binding motif. Introduction of the mutation that encodes the E484K substitution in the B.1.1.7 background to reflect a newly emerged variant of concern (VOC 202102/02) led to a more-substantial loss of neutralizing activity by vaccine-elicited antibodies and monoclonal antibodies (19 out of 31) compared with the loss of neutralizing activity conferred by the mutations in B.1.1.7 alone. The emergence of the E484K substitution in a B.1.1.7 background represents a threat to the efficacy of the BNT162b2 vaccine.
- Published
- 2021
24. Prenatal Exposure to Ambient Air Temperature and Risk of Early Delivery
- Author
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Spolter, F., primary, Kloog, I., additional, Dorman, M., additional, Novack, L., additional, Erez, O., additional, and Raz, R., additional
- Published
- 2020
- Full Text
- View/download PDF
25. An integrated national scale SARS-CoV-2 genomic surveillance network
- Author
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Aanensen, DM, Abudahab, K, Adams, A, Afifi, S, Alam, MT, Alderton, A, Alikhan, N-F, Allan, J, Almsaud, M, Alrezaihi, A, Alruwaili, M, Amato, R, Andersson, M, Angyal, A, Aranday-Cortes, E, Ariani, C, Armstrong, SD, Asamaphan, P, Attwood, S, Aydin, A, Badhan, A, Baker, D, Baker, P, Balcazar, CE, Ball, J, Barton, AE, Bashton, M, Baxter, L, Beale, M, Beaver, C, Beckett, A, Beer, R, Beggs, A, Bell, A, Bellis, KL, Bentley, EG, Berriman, M, Betteridge, E, Bibby, D, Bicknell, K, Birchley, A, Black, G, Blane, B, Bloomfield, S, Bolt, F, Bonsall, DG, Bosworth, A, Bourgeois, Y, Boyd, O, Bradshaw, D, Breuer, J, Bridgewater, H, Brooks, T, Broos, A, Brown, JR, Brown, RL, Brunker, K, Bucca, G, Buck, D, Bull, M, Butcher, E, Caddy, SL, Caller, LG, Cambell, S, Carlile, M, Carmichael, S, Carrilero, L, Castellano, S, Chaloner, J, Chand, M, Chapman, MR, Chappell, J, Charles, I, Chauhan, AJ, Chawla, A, Cheng, E, Churcher, CM, Clark, G, Clark, JJ, Collins, J, Colquhoun, R, Connor, TR, Constantinidou, C, Coombes, J, Corden, S, Cottrell, S, Cowell, A, Curran, MD, Curran, T, Dabrera, G, Danesh, J, Darby, AC, De Cesare, M, Martins, LDO, De Silva, TI, Debebe, B, Dervisevic, S, Dewar, RA, Dia, M, Dorman, M, Dougan, G, Dover, L, Downing, F, Drury, E, Du Plessis, L, Dyal, PL, Eccles, R, Edwards, S, Ellaby, N, Elliott, S, Eltringham, G, Elumogo, N, Essex, S, Evans, CM, Evans, J, Nascimento, FF, Fairley, DJ, Farr, B, Feltwell, T, Ferguson, N, Filipe, ADS, Findlay, J, Forrest, LM, Forrest, S, Foulser, L, Francois, S, Fraser, C, Frost, L, Gallagher, E, Gallagher, MD, Garcia-Dorival, I, Gaskin, A, Gatica-Wilcox, B, Gavriil, A, Geidelberg, L, Gemmell, M, Gerada, A, Gifford, L, Gilbert, L, Gilmore, P, Gilroy, R, Girgis, S, Glaysher, S, Golubchik, T, Goncalves, S, Goodfellow, I, Goodwin, S, Graham, C, Graham, L, Grammatopoulos, D, Green, A, Green, LR, Greenaway, J, Gregory, R, Groves, DC, Groves, N, Guest, M, Gunson, R, Haldenby, S, Hall, G, Hamilton, WL, Han, X, Harris, KA, Harrison, EM, Hartley, C, Herrera, C, Hesketh, A, Heyburn, D, Hill, V, Hiscox, JA, Holden, M, Holmes, A, Holmes, N, Holt, GS, Hopes, R, Hosmillo, M, Houldcroft, CJ, Howson-Wells, H, Hubb, J, Hughe, J, Hughes, M, Hutchings, S, Impey, R, Iturriza-Gomara, M, Jackson, A, Jackson, B, Jackson, DK, Jahun, AS, James, K, Jamrozy, D, Jeffries, A, Jesudason, N, John, M, Johnson, J, Johnson, KJ, Johnson, N, Johnston, I, Jones, B, Jones, R, Jones, S, Jorgensen, D, Kane, L, Kay, GL, Kay, S, Keatley, J-P, Keeley, AJ, Khakh, M, Khokhar, FA, Kitchen, C, Knight, B, Kolyva, A, Kraemer, M, Kristiansen, M, Kumziene-Summerhayes, S, Kwiatkowski, D, Lackenby, A, Langford, C, Lawniczak, M, Thanh, L-V, Lee, D, Letchford, L, Li, K, Li, L, Liggett, S, Lindsey, BB, Livett, R, Lloyd, A, Lo, S, Lockhart, M, Loh, J, Loman, NJ, Loose, M, Lucaci, A, Ludden, C, Luu, L, Lyons, RA, MacIntyre-Cockett, G, MacLean, A, Mair, D, Maksimovic, J, Manley, R, Manso, C, Manson, J, Martincorena, I, Masoli, J, Mather, AE, Mbisa, T, McCluggage, K, McClure, P, McCrone, JT, McDonald, S, McHugh, MP, McKenna, JM, McMinn, L, McMurray, C, Meadows, L, Menegazzo, M, Meredith, LW, Merrick, I, Mestek-Boukhibar, L, Miah, S, Michell, S, Michelsen, ML, Molnar, Z, Moore, C, Moore, N, Morgan, M, Morgan, S, Muddyman, D, Muir, DA, Muir, P, Myers, R, Nastouli, E, Naydenova, P, Nelson, A, Nelson, C, Nelson, R, Nicholls, S, Nichols, J, Niebel, M, Niola, P, Nomikou, K, O'Grady, J, O'Toole, AN, O'Toole, E, Olateju, C, Orton, RJ, Osman, H, Ott, S, Pacchiarini, N, Padgett, D, Page, AJ, Palmer, S, Panchbhaya, YN, Pandey, S, Park, N, Parker, MD, Parkhill, J, Parr, YA, Parsons, PJ, Partridge, DG, Patel, M, Patterson, S, Payne, B, Peacock, SJ, Penrice-Randal, R, Perry, M, Platt, S, Poplawski, R, Prakash, R, Prestwood, L, Price, A, Price, JR, Puethe, C, Pybus, O, Pymont, H, Quail, M, Quick, J, Raghwani, J, Ragonnet-Cronin, M, Rahman, S, Rainbow, L, Rajatileka, S, Rambaut, A, Ramsay, M, Randell, PA, Randle, NP, Raviprakash, V, Raza, M, Silva, PR, Rey, S, Richter, A, Robertson, DL, Robinson, TI, Robson, SC, Rooke, S, Rowan, A, Rowe, W, Roy, S, Rudder, S, Ruis, C, Sang, F, Scarlett, G, Schaefer, U, Scott, C, Scott, G, Sethi, D, Shaaban, S, Shah, R, Sharma, P, Shawli, GT, Shepherd, J, Sherriff, N, Shirley, L, Sillitoe, J, Simpson, DA, Singer, JB, Siveroni, I, Smith, C, Smith, CP, Smith, DL, Smith, N, Smith, W, Smith-Palmer, A, Smollett, K, Southgate, J, Spellman, K, Spencer-Chapman, M, Sridhar, S, Stanley, R, Stark, R, Stewart, JP, Stockton, J, Stuart, C, Studholme, D, Swainston, N, Swindells, E, Taha, Y, Tariq, MA, Taylor, B, Taylor, GP, Taylor, S, Taylor-Joyce, G, Tedim, AP, Temperton, B, Templeton, KE, Thomson, EC, Thomson, NM, Thornton, A, Thurston, S, Todd, J, Tong, L, Tonkin-Hill, G, Torok, ME, Trebes, A, Trotter, AJ, Tsoleridis, T, Tucker, RM, Tutill, HJ, Underwood, A, Unnikrishnan, M, Vamos, E, Vasylyeva, T, Vattipally, S, Victoria, A, Vipond, B, Volz, EM, Wain, J, Wang, D, Warwick-Dugdale, J, Wastnedge, E, Watkins, J, Watts, J, Webber, M, Weeks, S, Weldon, D, Whitehead, M, Williams, CA, Williams, C, Williams, D, Williams, R, Williams, TC, Wise, E, Wright, V, Wyles, MD, Wyllie, S, Yakovleva, A, Yasir, M, Yeats, C, Yew, WC, Young, GR, Yu, X, and Zarebski, A
- Subjects
Microbiology (medical) ,Scale (ratio) ,SARS-CoV-2 ,viruses ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,COVID-19 ,COVID-19 Genomics UK (COG-UK) consortiumcontact@cogconsortium.uk ,C500 ,Genome, Viral ,Genomics ,Biology ,C700 ,Microbiology ,Article ,Infectious Diseases ,Virology ,Humans ,Cartography - Abstract
The Coronavirus Disease 2019 (COVID-19) Genomics UK Consortium (COG-UK) was launched in March, 2020, with £20 million support from UK Research and Innovation, the UK Department of Health and Social Care, and Wellcome Trust. The goal of this consortium is to sequence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for up to 230 000 patients, health-care workers, and other essential workers in the UK with COVID-19, which will help to enable the tracking of SARS-CoV-2 transmission, identify viral mutations, and integrate with health data to assess how the viral genome interacts with cofactors and consequences of COVID-19.
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- 2020
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26. Letter to the Editor
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Mellor, A. C., Dorman, M. L., and Girdler, N. M.
- Published
- 2006
27. The use of an intra-oral injection of ketorolac in the treatment of irreversible pulpitis
- Author
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Mellor, A. C., Dorman, M. L., and Girdler, N. M.
- Published
- 2005
28. Evaluation of effectiveness of the PlasmaJet surgical device in the treatment of advanced stage ovarian cancer (PlaComOv-study): study protocol of a randomized controlled trial in the Netherlands
- Author
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Boer, G.M. (Geertje) de, Hofhuis, W., Reesink-Peters, N., Ewing-Graham, P.C., Schoots, I.G. (Ivo), Beltman, J.J., Piek, J.M.J., Baalbergen, A., Kooi, G.S. (Sjarlot), van Haaften, A., van Huisseling, H., Haans, L., Dorman, M., Beekhuizen, H.J. (Heleen) van, Boer, G.M. (Geertje) de, Hofhuis, W., Reesink-Peters, N., Ewing-Graham, P.C., Schoots, I.G. (Ivo), Beltman, J.J., Piek, J.M.J., Baalbergen, A., Kooi, G.S. (Sjarlot), van Haaften, A., van Huisseling, H., Haans, L., Dorman, M., and Beekhuizen, H.J. (Heleen) van
- Abstract
Background: The most important goal for survival benefit of advanced stage ovarian cancer is to surgically remove all visible tumour, because complete cytoreductive surgery (CCS) has been shown to be associated with prolonged survival. In a remarkable number of women, CCS is very challenging. Especially in women with many small metastases on the peritoneum and intestinal surface, conventional CCS with electrosurgery is not able to be “complete” in removing safely all visible tumour. In this randomized controlled trail (RCT) we investigate whether the use of the PlasmaJet Surgical Device increases the rate of CCS, and whether this indeed leads to a longer progression free and overall survival. The main research question is: does the use of the PlasmaJet Surgical Device in surgery for advanced stage ovarian cancer result in an increased number of complete cytoreductive surgeries when compared with conventional surgical techniques. Secondary study objectives are: 30-day morbidity, duration of surgery, blood loss, length of hospitalisation, Quality of Life, disease-free survival, overall survival, percentage colostomy, cost-effectiveness. Methods: The study design is a multicentre single-blinded superiority RCT in two university and nine non-university hospitals in The Netherlands. Three hundred and thirty women undergoing cytoreductive surgery for advanced stage ovarian carcinoma (FIGO Stage IIIB-IV) will be randomized into two arms: use of the PlasmaJet (intervention group) versus the use of standard surgical instruments combined with electrocoagulation (control group). The primary outcome is the rate of complete cytoreductive surgery in both groups. Secondary study objectives are: 30-day morbidity, duration of surgery, blood loss, length of hospitalisation, Quality of Life, disease-free survival, overall survival, percentage colostomy, cost-effectiveness. Quality of life will be evaluated using validated questionnaires at baseline, at 1 and 6 months after surgery and
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- 2019
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29. Evaluation of effectiveness of the PlasmaJet surgical device in the treatment of advanced stage ovarian cancer (PlaComOv-study): study protocol of a randomized controlled trial in the Netherlands
- Author
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Boer, Gatske, Hofhuis, W, Reesink-Peters, N, Graham, Patricia, Schoots, Ivo, Beltman, JJ, Piek, JMJ, Baalbergen, A, Kooi, GS, van Haaften, A, van Huisseling, H, Haans, L, Dorman, M, Beekhuizen, Heleen, Boer, Gatske, Hofhuis, W, Reesink-Peters, N, Graham, Patricia, Schoots, Ivo, Beltman, JJ, Piek, JMJ, Baalbergen, A, Kooi, GS, van Haaften, A, van Huisseling, H, Haans, L, Dorman, M, and Beekhuizen, Heleen
- Published
- 2019
30. A synthesis of radial growth patterns preceding tree mortality
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Cailleret, M., Jansen, S., Robert, E. M. R., Desoto, L., Aakala, T., Antos, J. A., Beikircher, B., Bigler, C., Bugmann, H., Caccianiga, M., Čada, V., Camarero, J. J., Cherubini, P., Cochard, H., Coyea, M. R., Čufar, K., Das, A. J., Davi, H., Delzon, S., Dorman, M., Gea Izquierdo, Guillermo, Gillner, S., Haavik, L. J., Hartmann, H., Hereş, A. M., Hultine, K. R., Janda, P., Kane, J. M., Kharuk, V. I., Kitzberger, T., Klein, T., Kramer, K., Lens, F., Levanic, T., Linares Calderon, J. C., Lloret, F., Lobo-Do-Vale, R., Lombardi, F., López Rodríguez, R., Mäkinen, H., Mayr, S., Mészáros, I., Metsaranta, J. M., Minunno, F., Oberhuber, W., Papadopoulos, A., Peltoniemi, M., Petritan, A. M., Rohner, B., Sangüesa-Barreda, G., Sarris, D., Smith, J. M., Stan, A. B., Sterck, F., Stojanović, D. B., Suarez, M. L., Svoboda, M., Tognetti, R., Torres-Ruiz, J. M., Trotsiuk, V., Villalba, R., Vodde, F., Westwood, A. R., Wyckoff, P. H., Zafirov, N., Martínez-Vilalta, J., Cailleret, M., Jansen, S., Robert, E. M. R., Desoto, L., Aakala, T., Antos, J. A., Beikircher, B., Bigler, C., Bugmann, H., Caccianiga, M., Čada, V., Camarero, J. J., Cherubini, P., Cochard, H., Coyea, M. R., Čufar, K., Das, A. J., Davi, H., Delzon, S., Dorman, M., Gea Izquierdo, Guillermo, Gillner, S., Haavik, L. J., Hartmann, H., Hereş, A. M., Hultine, K. R., Janda, P., Kane, J. M., Kharuk, V. I., Kitzberger, T., Klein, T., Kramer, K., Lens, F., Levanic, T., Linares Calderon, J. C., Lloret, F., Lobo-Do-Vale, R., Lombardi, F., López Rodríguez, R., Mäkinen, H., Mayr, S., Mészáros, I., Metsaranta, J. M., Minunno, F., Oberhuber, W., Papadopoulos, A., Peltoniemi, M., Petritan, A. M., Rohner, B., Sangüesa-Barreda, G., Sarris, D., Smith, J. M., Stan, A. B., Sterck, F., Stojanović, D. B., Suarez, M. L., Svoboda, M., Tognetti, R., Torres-Ruiz, J. M., Trotsiuk, V., Villalba, R., Vodde, F., Westwood, A. R., Wyckoff, P. H., Zafirov, N., and Martínez-Vilalta, J.
- Abstract
Tree mortality is a key factor influencing forest functions and dynamics, but our understanding of the mechanisms leading to mortality and the associated changes in tree growth rates are still limited. We compiled a new pan-continental tree-ring width database from sites where both dead and living trees were sampled (2970 dead and 4224 living trees from 190 sites, including 36 species), and compared early and recent growth rates between trees that died and those that survived a given mortality event. We observed a decrease in radial growth before death in ca. 84% of the mortality events. The extent and duration of these reductions were highly variable (1-100 years in 96% of events) due to the complex interactions among study species and the source(s) of mortality. Strong and long-lasting declines were found for gymnosperms, shade- and drought-tolerant species, and trees that died from competition. Angiosperms and trees that died due to biotic attacks (especially bark-beetles) typically showed relatively small and short-term growth reductions. Our analysis did not highlight any universal trade-off between early growth and tree longevity within a species, although this result may also reflect high variability in sampling design among sites. The intersite and interspecific variability in growth patterns before mortality provides valuable information on the nature of the mortality process, which is consistent with our understanding of the physiological mechanisms leading to mortality. Abrupt changes in growth immediately before death can be associated with generalized hydraulic failure and/or bark-beetle attack, while long-term decrease in growth may be associated with a gradual decline in hydraulic performance coupled with depletion in carbon reserves. Our results imply that growth-based mortality algorithms may be a powerful tool for predicting gymnosperm mortality induced by chronic stress, but not necessarily so for angiosperms and in case of intense drought or bark
- Published
- 2017
31. A synthesis of radial growth patterns preceding tree mortality
- Author
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Ministerio de Economía y Competitividad (España), Cailleret, Maxime, Jansen, S., Robert, E. M. R., DeSoto, Lucía, Aakala, T., Antos, J. A., Beikircher, B., Bigler, C., Bugmann, H., Caccianiga, Marco, Cada, V., Camarero, Jesús Julio, Cherubini, Paolo, Cochard, H., Coyea, M. R., Cufar, Katarina, Das, Adrian J., Davi, H., Delzon, S., Dorman, M., Gea Izquierdo, Guillermo, Gillner, S., Haavik, L. J., Hartmann, H., Hereş, Ana-María, Hultine, K. R., Janda, P., Kane, J. M., Kharuk, V. I., Kitzberger, Thomas, Klein, T., Kramer, K., Lens, F., Levanic, T., Linares, Juan Carlos, Lloret, Francisco, Lobo-Do-Vale, R., Lombardi, Fabio, López Rodríguez, R., Mäkinen, H., Mayr, S., Mészáros, Itzván, Metsaranta, J. M., Minunno, F., Oberhuber, W., Papadopoulos, A., Peltoniemi, M., Petritan, A.M., Rohner, B., Sangüesa-Barreda, G., Martínez-Vilalta, Jordi, Ministerio de Economía y Competitividad (España), Cailleret, Maxime, Jansen, S., Robert, E. M. R., DeSoto, Lucía, Aakala, T., Antos, J. A., Beikircher, B., Bigler, C., Bugmann, H., Caccianiga, Marco, Cada, V., Camarero, Jesús Julio, Cherubini, Paolo, Cochard, H., Coyea, M. R., Cufar, Katarina, Das, Adrian J., Davi, H., Delzon, S., Dorman, M., Gea Izquierdo, Guillermo, Gillner, S., Haavik, L. J., Hartmann, H., Hereş, Ana-María, Hultine, K. R., Janda, P., Kane, J. M., Kharuk, V. I., Kitzberger, Thomas, Klein, T., Kramer, K., Lens, F., Levanic, T., Linares, Juan Carlos, Lloret, Francisco, Lobo-Do-Vale, R., Lombardi, Fabio, López Rodríguez, R., Mäkinen, H., Mayr, S., Mészáros, Itzván, Metsaranta, J. M., Minunno, F., Oberhuber, W., Papadopoulos, A., Peltoniemi, M., Petritan, A.M., Rohner, B., Sangüesa-Barreda, G., and Martínez-Vilalta, Jordi
- Abstract
Tree mortality is a key factor influencing forest functions and dynamics, but our understanding of the mechanisms leading to mortality and the associated changes in tree growth rates are still limited. We compiled a new pan-continental tree-ring width database from sites where both dead and living trees were sampled (2970 dead and 4224 living trees from 190 sites, including 36 species), and compared early and recent growth rates between trees that died and those that survived a given mortality event. We observed a decrease in radial growth before death in ca. 84% of the mortality events. The extent and duration of these reductions were highly variable (1–100 years in 96% of events) due to the complex interactions among study species and the source(s) of mortality. Strong and long-lasting declines were found for gymnosperms, shade- and drought-tolerant species, and trees that died from competition. Angiosperms and trees that died due to biotic attacks (especially bark-beetles) typically showed relatively small and short-term growth reductions. Our analysis did not highlight any universal trade-off between early growth and tree longevity within a species, although this result may also reflect high variability in sampling design among sites. The intersite and interspecific variability in growth patterns before mortality provides valuable information on the nature of the mortality process, which is consistent with our understanding of the physiological mechanisms leading to mortality. Abrupt changes in growth immediately before death can be associated with generalized hydraulic failure and/or bark-beetle attack, while long-term decrease in growth may be associated with a gradual decline in hydraulic performance coupled with depletion in carbon reserves. Our results imply that growth-based mortality algorithms may be a powerful tool for predicting gymnosperm mortality induced by chronic stress, but not necessarily so for angiosperms and in case of intense drought or bark
- Published
- 2017
32. Crack growth at fastener holes containing intergranular cracking
- Author
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Lo, M., primary, Jones, R., additional, Bowler, A., additional, Dorman, M., additional, and Edwards, D., additional
- Published
- 2017
- Full Text
- View/download PDF
33. Can intravenous conscious sedation with midazolam be effective at facilitating surgical dentistry in adolescent orthodontic patients? A service evaluation
- Author
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Stamp, A. J., primary, Dorman, M. L., additional, Vernazza, C. R., additional, Deeming, G., additional, Reid, C., additional, Wilson, K. E., additional, and Girdler, N. M., additional
- Published
- 2017
- Full Text
- View/download PDF
34. Stop-consonant recognition: Release bursts and formant transitions as functionally equivalent, context-dependent cues
- Author
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Dorman, M. F., Studdert-Kennedy, M., and Raphael, L. J.
- Published
- 1977
- Full Text
- View/download PDF
35. Measurement of the Neutrino Mass Splitting and Flavor Mixing by MINOS
- Author
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Adamson, P., Andreopoulos, C., Armstrong, R., Auty, D. J., Ayres, D. S., Backhouse, C., Barr, G., Bishai, M., Blake, A., Bock, G. J., Boehnlein, D. J., Bogert, D., Cavanaugh, S., Cherdack, D., Childress, S., Choudhary, B. C., Coelho, J. A. B., Coleman, S. J., Corwin, L., Cronin-Hennessy, D., Danko, I. Z., de Jong, J. K., Devenish, N. E., Diwan, M. V., Dorman, M., Escobar, C. O., Evans, J. J., Falk, E., Feldman, G. J., Frohne, M. V., Gallagher, H. R., Gomes, R. A., Goodman, M. C., Gouffon, P., Graf, N., Gran, R., Grant, N., Grzelak, K., Habig, A., Harris, D., Hartnell, J., Hatcher, R., Himmel, A., Holin, A., Huang, X., Hylen, J., Ilic, J., Irwin, G. M., Isvan, Z., Jaffe, D. E., James, C., Jensen, D., Kafka, T., Kasahara, S. M. S., Koizumi, G., Kopp, S., Kordosky, M., Kreymer, A., Lang, K., Lefeuvre, G., Ling, J., Litchfield, P. J., Litchfield, R. P., Loiacono, L., Lucas, P., Mann, W. A., Marshak, M. L., Mayer, N., McGowan, A. M., Mehdiyev, R., Meier, J. R., Messier, M. D., Michael, D. G., Miller, W. H., Mishra, S. R., Mitchell, J., Moore, C. D., Moffin, J., Mualem, L., Mufson, S., Musser, J., Naples, D., Nelson, J. K., Newman, H. B., Nichol, R. J., Nowak, J. A., Oliver, W. P., Orchanian, M., Ospanov, R., Paley, J., Patterson, R. B., Pawloski, G., Pearce, G. F., Petyt, D. A., Phan-Budd, S., Plunkett, R. K., Qiu, X., Ratchford, J., Raufer, T. M., Rebel, B., Rodrigues, P. A., Rosenfeld, C., Rubin, H. A., Sanchez, M. C., Schneps, J., Schreiner, P., Shanahan, P., Smith, C., Sousa, A., Stamoulis, P., Strait, M., Tagg, N., Talaga, R. L., Thomas, J., Thomson, M. A., Tinti, G., Toner, R., Tzanakos, G., Urheim, J., Vahle, P., Viren, B., Weber, A., Webb, R. C., White, C., Whitehead, L., Wojcicki, S. G., Yang, T., Zwaska, R., and MINOS, Collaboration
- Subjects
Physics ,Particle physics ,Physics::Instrumentation and Detectors ,Solar neutrino ,High Energy Physics::Phenomenology ,General Physics and Astronomy ,FOS: Physical sciences ,Solar neutrino problem ,LEPTON CHARGE ,NuMI ,High Energy Physics - Experiment ,Nuclear physics ,High Energy Physics - Experiment (hep-ex) ,MINOS ,Measurements of neutrino speed ,High Energy Physics::Experiment ,Neutrino ,Neutrino oscillation ,Lepton - Abstract
Measurements of neutrino oscillations using the disappearance of muon neutrinos from the Fermilab NuMI neutrino beam as observed by the two MINOS detectors are reported. New analysis methods have been applied to an enlarged data sample from an exposure of $7.25 \times 10^{20}$ protons on target. A fit to neutrino oscillations yields values of $|\Delta m^2| = (2.32^{+0.12}_{-0.08})\times10^{-3}$\,eV$^2$ for the atmospheric mass splitting and $\rm \sin^2\!(2\theta) > 0.90$ (90%\,C.L.) for the mixing angle. Pure neutrino decay and quantum decoherence hypotheses are excluded at 7 and 9 standard deviations, respectively., Comment: 5 pages, 4 figures
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- 2011
36. Observation in the MINOS far detector of the shadowing of cosmic rays by the sun and moon
- Author
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Adamson, P. Andreopoulos, C. Ayres, D.S. Backhouse, C. Barr, G. Barrett, W.L. Bishai, M. Blake, A. Bock, B. Bock, G.J. Boehnlein, D.J. Bogert, D. Bower, C. Budd, S. Cavanaugh, S. Cherdack, D. Childress, S. Choudhary, B.C. Cobb, J.H. Coelho, J.A.B. Coleman, S.J. Corwin, L. Cronin-Hennessy, D. Danko, I.Z. De Jong, J.K. Devenish, N.E. Diwan, M.V. Dorman, M. Escobar, C.O. Evans, J.J. Falk, E. Feldman, G.J. Frohne, M.V. Gallagher, H.R. Godley, A. Gomes, R.A. Goodman, M.C. Gouffon, P. Gran, R. Grant, N. Grashorn, E.W. Grzelak, K. Habig, A. Harris, D. Harris, P.G. Hartnell, J. Hatcher, R. Himmel, A. Holin, A. Huang, X. Hylen, J. Ilic, J. Irwin, G.M. Isvan, Z. Jaffe, D.E. James, C. Jensen, D. Kafka, T. Kasahara, S.M.S. Koizumi, G. Kopp, S. Kordosky, M. Krahn, Z. Kreymer, A. Lang, K. Lefeuvre, G. Ling, J. Litchfield, P.J. Litchfield, R.P. Loiacono, L. Lucas, P. Mann, W.A. Marshak, M.L. Marshall, J.S. Mayer, N. McGowan, A.M. Mehdiyev, R. Meier, J.R. Messier, M.D. Michael, D.G. Miller, W.H. Mishra, S.R. Mitchell, J. Moore, C.D. Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J.K. Newman, H.B. Nichol, R.J. Nicholls, T.C. Oliver, W.P. Orchanian, M. Paley, J. Patterson, R.B. Pawloski, G. Pearce, G.F. Peterson, E.A. Pittam, R. Plunkett, R.K. Ratchford, J. Raufer, T.M. Rebel, B. Reichenbacher, J. Rodrigues, P.A. Rosenfeld, C. Rubin, H.A. Ryabov, V.A. Sanchez, M.C. Schneps, J. Schreiner, P. Semenov, V.K. Shanahan, P. Sousa, A. Strait, M. Tagg, N. Talaga, R.L. Thomas, J. Thomson, M.A. Thron, J.L. Tinti, G. Toner, R. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R.C. White, C. Whitehead, L. Wojcicki, S.G. Wright, D.M. Yang, T. Zwaska, R.
- Subjects
Physics::Space Physics ,High Energy Physics::Experiment ,Astrophysics::Earth and Planetary Astrophysics - Abstract
The shadowing of cosmic ray primaries by the moon and sun was observed by the MINOS far detector at a depth of 2070 mwe using 83.54 million cosmic ray muons accumulated over 1857.91 live-days. The shadow of the moon was detected at the 5.6 σ level and the shadow of the sun at the 3.8 σ level using a log-likelihood search in celestial coordinates. The moon shadow was used to quantify the absolute astrophysical pointing of the detector to be 0.17 ± 0.12°. Hints of interplanetary magnetic field effects were observed in both the sun and moon shadow. © 2010 Elsevier B.V. All rights reserved.
- Published
- 2011
37. Measurement of the Neutrino Mass Splitting and Flavor Mixing by MINOS
- Author
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Adamson, P. Andreopoulos, C. Armstrong, R. Auty, D. J. and Ayres, D. S. Backhouse, C. Barr, G. Bishai, M. Blake, A. and Bock, G. J. Boehnlein, D. J. Bogert, D. Cavanaugh, S. and Cherdack, D. Childress, S. Choudhary, B. C. Coelho, J. A. B. Coleman, S. J. Corwin, L. Cronin-Hennessy, D. and Danko, I. Z. de Jong, J. K. Devenish, N. E. Diwan, M. V. and Dorman, M. Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. Frohne, M. V. Gallagher, H. R. Gomes, R. A. and Goodman, M. C. Gouffon, P. Graf, N. Gran, R. Grant, N. and Grzelak, K. Habig, A. Harris, D. Hartnell, J. and Hatcher, R. Himmel, A. Holin, A. Huang, X. Hylen, J. and Ilic, J. Irwin, G. M. Isvan, Z. Jaffe, D. E. James, C. and Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. and Kopp, S. Kordosky, M. Kreymer, A. Lang, K. Lefeuvre, G. and Ling, J. Litchfield, P. J. Litchfield, R. P. Loiacono, L. Lucas, P. Mann, W. A. Marshak, M. L. Mayer, N. and McGowan, A. M. Mehdiyev, R. Meier, J. R. Messier, M. D. and Michael, D. G. Miller, W. H. Mishra, S. R. Mitchell, J. and Moore, C. D. Moffin, J. Mualem, L. Mufson, S. Musser, J. and Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. and Nowak, J. A. Oliver, W. P. Orchanian, M. Ospanov, R. and Paley, J. Patterson, R. B. Pawloski, G. Pearce, G. F. and Petyt, D. A. Phan-Budd, S. Plunkett, R. K. Qiu, X. and Ratchford, J. Raufer, T. M. Rebel, B. Rodrigues, P. A. and Rosenfeld, C. Rubin, H. A. Sanchez, M. C. Schneps, J. and Schreiner, P. Shanahan, P. Smith, C. Sousa, A. and Stamoulis, P. Strait, M. Tagg, N. Talaga, R. L. Thomas, J. Thomson, M. A. Tinti, G. Toner, R. Tzanakos, G. and Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R. C. and White, C. Whitehead, L. Wojcicki, S. G. Yang, T. Zwaska, R. MINOS Collaboration
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Physics::Instrumentation and Detectors ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
Measurements of neutrino oscillations using the disappearance of muon neutrinos from the Fermilab NuMI neutrino beam as observed by the two MINOS detectors are reported. New analysis methods have been applied to an enlarged data sample from an exposure of 7.25 x 10(20) protons on target. A fit to neutrino oscillations yields values of vertical bar Delta m(2)vertical bar = (2.32(-0.08)(+0.12) x 10(-3) eV(2) for the atmospheric mass splitting and sin(2)(2 theta) > 0.90 (90% C.L.) for the mixing angle. Pure neutrino decay and quantum decoherence hypotheses are excluded at 7 and 9 standard deviations, respectively.
- Published
- 2011
38. Measurement of the underground atmospheric muon charge ratio using the MINOS Near Detector
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Adamson, P. Andreopoulos, C. Auty, D. J. Ayres, D. S. and Backhouse, C. Barr, G. Barrett, W. L. Bhattarai, P. and Bishai, M. Blake, A. Bock, G. J. Boehnlein, D. J. and Bogert, D. Budd, S. Cavanaugh, S. Cherdack, D. and Childress, S. Choudhary, B. C. Coelho, J. A. B. Coleman, S. J. Corwin, L. Cronin-Hennessy, D. Damiani, D. Danko, I. Z. de Jong, J. K. Devenish, N. E. Diwan, M. V. Dorman, M. Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. and Fields, T. H. Frohne, M. V. Gallagher, H. R. Gomes, R. A. Goodman, M. C. Gouffon, P. Graf, N. Gran, R. and Grant, N. Grzelak, K. Habig, A. Harris, D. Harris, P. G. and Hartnell, J. Hatcher, R. Himmel, A. Holin, A. Huang, X. Hylen, J. Ilic, J. Irwin, G. M. Isvan, Z. Jaffe, D. E. James, C. Jensen, D. Kafka, T. Kasahara, S. M. S. and Koizumi, G. Kopp, S. Kordosky, M. Krahn, Z. Kreymer, A. Lang, K. Lefeuvre, G. Ling, J. Litchfield, P. J. and Loiacono, L. Lucas, P. Mann, W. A. Marshak, M. L. Mayer, N. McGowan, A. M. Mehdiyev, R. Meier, J. R. Messier, M. D. Michael, D. G. Miller, W. H. Mishra, S. R. Mitchell, J. Moore, C. D. Morfin, J. Mualem, L. Mufson, S. and Musser, J. Naples, D. Nelson, J. K. Newman, H. B. and Nichol, R. J. Nowak, J. A. Oliver, W. P. Orchanian, M. and Paley, J. Patterson, R. B. Pawloski, G. Pearce, G. F. and Pittam, R. Plunkett, R. K. Qiu, X. Ratchford, J. Raufer, T. M. Rebel, B. Reichenbacher, J. Rodrigues, P. A. and Rosenfeld, C. Rubin, H. A. Ryabov, V. A. Sanchez, M. C. and Saoulidou, N. Schneps, J. Schreiner, P. Shanahan, P. and Sousa, A. Strait, M. Tagg, N. Talaga, R. L. Thomas, J. and Thomson, M. A. Tinti, G. Toner, R. Tzanakos, G. and Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R. C. and White, C. Whitehead, L. Wojcicki, S. G. Wright, D. M. and Yang, T. Zwaska, R.
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Physics::Instrumentation and Detectors ,High Energy Physics::Experiment ,Astrophysics::Earth and Planetary Astrophysics ,Nuclear Experiment - Abstract
The magnetized MINOS Near Detector, at a depth of 225 mwe, is used to measure the atmospheric muon charge ratio. The ratio of observed positive to negative atmospheric muon rates, using 301 days of data, is measured to be 1.266 +/- 0.001(stat)(-0.014)(+0.015)(syst). This measurement is consistent with previous results from other shallow underground detectors and is 0.108 +/- 0.019(stat + syst) lower than the measurement at the functionally identical MINOS Far Detector at a depth of 2070 mwe. This increase in charge ratio as a function of depth is consistent with an increase in the fraction of muons arising from kaon decay for increasing muon surface energies.
- Published
- 2011
39. Improved search for muon-neutrino to electron-neutrino oscillations in MINOS
- Author
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Adamson, P. Auty, D.J. Ayres, D.S. Backhouse, C. Barr, G. Betancourt, M. Bishai, M. Blake, A. Bock, G.J. Boehnlein, D.J. Bogert, D. Cao, S.V. Cavanaugh, S. Cherdack, D. Childress, S. Coelho, J.A.B. Corwin, L. Cronin-Hennessy, D. Danko, I.Z. De Jong, J.K. Devenish, N.E. Diwan, M.V. Dorman, M. Escobar, C.O. Evans, J.J. Falk, E. Feldman, G.J. Frohne, M.V. Gallagher, H.R. Gomes, R.A. Goodman, M.C. Gouffon, P. Graf, N. Gran, R. Grzelak, K. Habig, A. Hartnell, J. Hatcher, R. Himmel, A. Holin, A. Huang, X. Hylen, J. Irwin, G.M. Isvan, Z. Jaffe, D.E. James, C. Jensen, D. Kafka, T. Kasahara, S.M.S. Koizumi, G. Kopp, S. Kordosky, M. Kreymer, A. Lang, K. Lefeuvre, G. Ling, J. Litchfield, P.J. Loiacono, L. Lucas, P. Mann, W.A. Marshak, M.L. Mathis, M. Mayer, N. McGowan, A.M. Mehdiyev, R. Meier, J.R. Messier, M.D. Michael, D.G. Miller, W.H. Mishra, S.R. Mitchell, J. Moore, C.D. Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J.K. Newman, H.B. Nichol, R.J. Nowak, J.A. Ochoa-Ricoux, J.P. Oliver, W.P. Orchanian, M. Paley, J. Patterson, R.B. Pawloski, G. Pearce, G.F. Phan-Budd, S. Plunkett, R.K. Qiu, X. Ratchford, J. Rebel, B. Rosenfeld, C. Rubin, H.A. Sanchez, M.C. Schneps, J. Schreckenberger, A. Schreiner, P. Shanahan, P. Sharma, R. Sousa, A. Tagg, N. Talaga, R.L. Thomas, J. Thomson, M.A. Toner, R. Torretta, D. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Walding, J.J. Weber, A. Webb, R.C. White, C. Whitehead, L. Wojcicki, S.G. Yang, T. Zwaska, R.
- Abstract
We report the results of a search for νe appearance in a νμ beam in the MINOS long-baseline neutrino experiment. With an improved analysis and an increased exposure of 8.2×1020 protons on the NuMI target at Fermilab, we find that 2sin2(θ23) sin2(2θ13)
- Published
- 2011
40. First Direct Observation of Muon Antineutrino Disappearance
- Author
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Adamson, P. Andreopoulos, C. Auty, D. J. Ayres, D. S. and Backhouse, C. Barr, G. Bishai, M. Blake, A. Bock, G. J. and Boehnlein, D. J. Bogert, D. Cavanaugh, S. Cherdack, D. and Childress, S. Choudhary, B. C. Coelho, J. A. B. Coleman, S. J. Corwin, L. Cronin-Hennessy, D. Danko, I. Z. de Jong, J. K. Devenish, N. E. Diwan, M. V. Dorman, M. and Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. and Frohne, M. V. Gallagher, H. R. Gomes, R. A. Goodman, M. C. and Gouffon, P. Graf, N. Gran, R. Grant, N. Grzelak, K. and Habig, A. Harris, D. Hartnell, J. Hatcher, R. and Himmel, A. Holin, A. Howcroft, C. Huang, X. Hylen, J. and Ilic, J. Irwin, G. M. Isvan, Z. Jaffe, D. E. James, C. Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. and Kopp, S. Kordosky, M. Kreymer, A. Lang, K. Lefeuvre, G. Ling, J. Litchfield, P. J. Loiacono, L. Lucas, P. and Mann, W. A. Marshak, M. L. Mayer, N. McGowan, A. M. and Mehdiyev, R. Meier, J. R. Messier, M. D. Miller, W. H. and Mishra, S. R. Mitchell, J. Moore, C. D. Morfin, J. and Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. Nicholls, T. C. Nowak, J. A. Ochoa-Ricoux, J. P. Oliver, W. P. Orchanian, M. and Ospanov, R. Paley, J. Patterson, R. B. Pawloski, G. and Pearce, G. F. Petyt, D. A. Phan-Budd, S. Plunkett, R. K. and Qiu, X. Ratchford, J. Raufer, T. M. Rebel, B. Rodrigues, P. A. Rosenfeld, C. Rubin, H. A. Sanchez, M. C. Schneps, J. Schreiner, P. Shanahan, P. Sousa, A. Stamoulis, P. and Strait, M. Tagg, N. Talaga, R. L. Tetteh-Lartey, E. and Thomas, J. Thomson, M. A. Tinti, G. Toner, R. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R. C. White, C. Whitehead, L. Wojcicki, S. G. Yang, T. and Zwaska, R. MINOS Collaboration
- Subjects
High Energy Physics::Experiment - Abstract
This Letter reports the first direct observation of muon antineutrino disappearance. The MINOS experiment has taken data with an accelerator beam optimized for (nu) over bar (mu) production, accumulating an exposure of 1.71 x 10(20) protons on target. In the Far Detector, 97 charged current (nu) over bar (mu) events are observed. The no-oscillation hypothesis predicts 156 events and is excluded at 6.3 sigma. The best fit to oscillation yields vertical bar Delta(m) over bar (2)vertical bar = [3.36(-0.40)(+0.46)(stat) +/- 0.06(sys)] x 10(-3) eV(2), sin(2)(2 (theta) over bar) = 0.86(-0.12)(+0.11)(stat) +/- 0.01(syst). The MINOS nu(mu) and (nu) over bar (mu) measurements are consistent at the 2.0% confidence level, assuming identical underlying oscillation parameters.
- Published
- 2011
41. Active to Sterile Neutrino Mixing Limits from Neutral-Current Interactions in MINOS
- Author
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Adamson, P. Auty, D. J. Ayres, D. S. Backhouse, C. Barr, G. Bishai, M. Blake, A. Bock, G. J. Boehnlein, D. J. and Bogert, D. Cavanaugh, S. Cherdack, D. Childress, S. and Coelho, J. A. B. Coleman, S. J. Corwin, L. Cronin-Hennessy, D. Danko, I. Z. de Jong, J. K. Devenish, N. E. Diwan, M. V. Dorman, M. Escobar, C. O. Evans, J. J. Falk, E. and Feldman, G. J. Frohne, M. V. Gallagher, H. R. Gomes, R. A. and Goodman, M. C. Gouffon, P. Graf, N. Gran, R. Grant, N. Grzelak, K. Habig, A. Harris, D. Hartnell, J. and Hatcher, R. Himmel, A. Holin, A. Huang, X. Hylen, J. and Ilic, J. Irwin, G. M. Isvan, Z. Jaffe, D. E. James, C. and Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. and Kopp, S. Kordosky, M. Kreymer, A. Lang, K. Lefeuvre, G. and Ling, J. Litchfield, P. J. Loiacono, L. Lucas, P. and Mann, W. A. Marshak, M. L. Mayer, N. McGowan, A. M. and Mehdiyev, R. Meier, J. R. Messier, M. D. Miller, W. H. and Mishra, S. R. Mitchell, J. Moore, C. D. Morfin, J. and Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. Nicholls, T. C. Nowak, J. A. Oliver, W. P. Orchanian, M. Paley, J. Patterson, R. B. Pawloski, G. Pearce, G. F. Petyt, D. A. Phan-Budd, S. and Pittam, R. Plunkett, R. K. Qiu, X. Ratchford, J. and Raufer, T. M. Rebel, B. Rodrigues, P. A. Rosenfeld, C. and Rubin, H. A. Sanchez, M. C. Schneps, J. Schreiner, P. and Sharma, R. Shanahan, P. Sousa, A. Stamoulis, P. Strait, M. Tagg, N. Talaga, R. L. Tetteh-Lartey, E. Thomas, J. and Thomson, M. A. Tinti, G. Toner, R. Torretta, D. and Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Walding, J. J. Weber, A. Webb, R. C. White, C. Whitehead, L. and Wojcicki, S. G. Zwaska, R.
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Physics::Instrumentation and Detectors ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
Results are reported from a search for active to sterile neutrino oscillations in the MINOS long-baseline experiment, based on the observation of neutral-current neutrino interactions, from an exposure to the NuMI neutrino beam of 7.07 x 10(20) protons on target. A total of 802 neutral-current event candidates is observed in the Far Detector, compared to an expected number of 754 +/- 28(stat) +/- 37(syst) for oscillations among three active flavors. The fraction f(s) of disappearing nu(mu) that may transition to nu(s) is found to be less than 22% at the 90% C.L.
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- 2011
42. Search for sterile neutrino mixing in the MINOS long-baseline experiment
- Author
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Adamson, P. Andreopoulos, C. Auty, D. J. Ayres, D. S. and Backhouse, C. Barnes, Jr., P. D. Barr, G. Barrett, W. L. and Bishai, M. Blake, A. Bock, G. J. Boehnlein, D. J. and Bogert, D. Bower, C. Cavanaugh, S. Chapman, J. D. and Cherdack, D. Childress, S. Choudhary, B. C. Coelho, J. A. B. and Cobb, J. H. Coleman, S. J. Cravens, J. P. and Cronin-Hennessy, D. Culling, A. J. Danko, I. Z. de Jong, J. K. Devenish, N. E. Diwan, M. V. Dorman, M. Erwin, A. R. and Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. and Frohne, M. V. Gallagher, H. R. Godley, A. Goodman, M. C. and Gouffon, P. Gran, R. Grashorn, E. W. Grzelak, K. Habig, A. Harris, D. Harris, P. G. Hartnell, J. Hatcher, R. and Heller, K. Himmel, A. Holin, A. Huang, X. Hylen, J. and Irwin, G. M. Isvan, Z. Jaffe, D. E. James, C. Jensen, D. and Kafka, T. Kasahara, S. M. S. Koizumi, G. Kopp, S. and Kordosky, M. Koskinen, D. J. Krahn, Z. Kreymer, A. Lang, K. Ling, J. Litchfield, P. J. Litchfield, R. P. and Loiacono, L. Lucas, P. Ma, J. Mann, W. A. Marchionni, A. and Marshak, M. L. Marshall, J. S. Mayer, N. McGowan, A. M. and Mehdiyev, R. Meier, J. R. Messier, M. D. Metelko, C. J. and Michael, D. G. Miller, W. H. Mishra, S. R. Mitchell, J. and Moore, C. D. Morfin, J. Mualem, L. Mufson, S. and Musser, J. Naples, D. Nelson, J. K. Newman, H. B. and Nichol, R. J. Nicholls, T. C. Ochoa-Ricoux, J. P. Oliver, W. P. Orchanian, M. Osiecki, T. Ospanov, R. Paley, J. and Paolone, V. Patterson, R. B. Pavlovic, Z. Pawloski, G. and Pearce, G. F. Pittam, R. Plunkett, R. K. Rahaman, A. and Rameika, R. A. Raufer, T. M. Rebel, B. Rodrigues, P. A. and Rosenfeld, C. Rubin, H. A. Ryabov, V. A. Sanchez, M. C. and Saoulidou, N. Schneps, J. Schreiner, P. Shanahan, P. and Smart, W. Smith, C. Sousa, A. Stamoulis, P. Strait, M. and Tagg, N. Talaga, R. L. Thomas, J. Thomson, M. A. and Tinti, G. Toner, R. Tzanakos, G. Urheim, J. Vahle, P. and Viren, B. Watabe, M. Weber, A. Webb, R. C. West, N. and White, C. Whitehead, L. Wojcicki, S. G. Wright, D. M. and Yang, T. Zhang, K. Zwaska, R. MINOS Collaboration
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Physics::Instrumentation and Detectors ,Astrophysics::High Energy Astrophysical Phenomena ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
A search for depletion of the combined flux of active neutrino species over a 735 km baseline is reported using neutral-current interaction data recorded by the MINOS detectors in the NuMI neutrino beam. Such a depletion is not expected according to conventional interpretations of neutrino oscillation data involving the three known neutrino flavors. A depletion would be a signature of oscillations or decay to postulated noninteracting sterile neutrinos, scenarios not ruled out by existing data. From an exposure of 3.18 x 10(20) protons on target in which neutrinos of energies between similar to 500 MeV and 120 GeV are produced predominantly as nu(mu), the visible energy spectrum of candidate neutral-current reactions in the MINOS far detector is reconstructed. Comparison of this spectrum to that inferred from a similarly selected near-detector sample shows that of the portion of the nu(mu) flux observed to disappear in charged-current interaction data, the fraction that could be converting to a sterile state is less than 52% at 90% confidence level (C. L.). The hypothesis that active neutrinos mix with a single sterile neutrino via oscillations is tested by fitting the data to various models. In the particular four-neutrino models considered, the mixing angles theta(24) and theta(34) are constrained to be less than 11 degrees and 56 degrees at 90% C. L., respectively. The possibility that active neutrinos may decay to sterile neutrinos is also investigated. Pure neutrino decay without oscillations is ruled out at 5.4 standard deviations. For the scenario in which active neutrinos decay into sterile states concurrently with neutrino oscillations, a lower limit is established for the neutrino decay lifetime tau(3)/m(3) > 2.1 x 10(-12) s/eV at 90% C.L.
- Published
- 2010
43. Observation of muon intensity variations by season with the MINOS far detector
- Author
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Adamson, P. Andreopoulos, C. Arms, K. E. Armstrong, R. and Auty, D. J. Ayres, D. S. Backhouse, C. Barnett, J. Barr, G. Barrett, W. L. Becker, B. R. Bishai, M. Blake, A. and Bock, B. Bock, G. J. Boehnlein, D. J. Bogert, D. Bower, C. Cavanaugh, S. Chapman, J. D. Cherdack, D. Childress, S. Choudhary, B. C. Cobb, J. H. Coleman, S. J. and Cronin-Hennessy, D. Culling, A. J. Danko, I. Z. de Jong, J. K. Devenish, N. E. Diwan, M. V. Dorman, M. Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. Fields, T. H. and Frohne, M. V. Gallagher, H. R. Godley, A. Goodman, M. C. and Gouffon, P. Gran, R. Grashorn, E. W. Grzelak, K. and Habig, A. Harris, D. Harris, P. G. Hartnell, J. Hatcher, R. Heller, K. Himmel, A. Holin, A. Hylen, J. Irwin, G. M. Isvan, Z. Jaffe, D. E. James, C. Jensen, D. and Kafka, T. Kasahara, S. M. S. Koizumi, G. Kopp, S. and Kordosky, M. Korman, K. Koskinen, D. J. Krahn, Z. and Kreymer, A. Lang, K. Ling, J. Litchfield, P. J. and Loiacono, L. Lucas, P. Ma, J. Mann, W. A. Marshak, M. L. and Marshall, J. S. Mayer, N. McGowan, A. M. Mehdiyev, R. and Meier, J. R. Messier, M. D. Metelko, C. J. Michael, D. G. Miller, Kw. H. Mishra, S. R. Mitchell, J. Moore, C. D. Morfin, J. Mualem, L. Mufson, S. Musser, J. and Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. and Nicholls, T. C. Ochoa-Ricoux, J. P. Oliver, W. P. Osiecki, T. Ospanov, R. Osprey, S. Paley, J. Patterson, R. B. and Patzak, T. Pawloski, G. Pearce, G. F. Peterson, E. A. and Pittam, R. Plunkett, R. K. Rahaman, A. Rameika, R. A. and Raufer, T. M. Rebel, B. Reichenbacher, J. Rodrigues, P. A. and Rosenfeld, C. Rubin, H. A. Ryabov, V. A. Sanchez, M. C. and Saoulidou, N. Schneps, J. Schreiner, P. Shanahan, P. and Smart, W. Smith, C. Sousa, A. Speakman, B. Stamoulis, P. and Strait, M. Tagg, N. Talaga, R. L. Thomas, J. and Thomson, M. A. Thron, J. L. Tinti, G. Toner, R. Tsarev, V. A. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. and Watabe, M. Weber, A. Webb, R. C. West, N. White, C. and Whitehead, L. Wojcicki, S. G. Wright, D. M. Yang, T. and Zois, M. Zhang, K. Zwaska, R. MINOS Collaboration
- Subjects
Physics::Instrumentation and Detectors ,Astrophysics::High Energy Astrophysical Phenomena ,High Energy Physics::Experiment - Abstract
The temperature of the upper atmosphere affects the height of primary cosmic ray interactions and the production of high-energy cosmic ray muons which can be detected deep underground. The MINOS far detector at Soudan, MN, has collected over 67 X 10(6) cosmic ray induced muons. The underground muon rate measured over a period of five years exhibits a 4% peak-to-peak seasonal variation which is highly correlated with the temperature in the upper atmosphere. The coefficient, alpha(T), relating changes in the muon rate to changes in atmospheric temperature was found to be alpha(T) 0: 873 +/- 0: 009(stat) +/- 0.010(syst). Pions and kaons in the primary hadronic interactions of cosmic rays in the atmosphere contribute differently to alpha(T) due to the different masses and lifetimes. This allows the measured value of alpha(T) to be interpreted as a measurement of the K/pi ratio for E-p greater than or similar to 7 TeV of 0.12(-0.05)(+0.07), consistent with the expectation from collider experiments.
- Published
- 2010
44. Neutrino and antineutrino inclusive charged-current cross section measurements with the MINOS near detector
- Author
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Adamson, P. Andreopoulos, C. Arms, K. E. Armstrong, R. and Auty, D. J. Ayres, D. S. Backhouse, C. Barnes, Jr., P. D. and Barr, G. Barrett, W. L. Bhattacharya, D. Bishai, M. and Blake, A. Bock, G. J. Boehnlein, D. J. Bogert, D. Bower, C. Cavanaugh, S. Chapman, J. D. Cherdack, D. Childress, S. Choudhary, B. C. Coelho, J. A. B. Coleman, S. J. and Cronin-Hennessy, D. Culling, A. J. Danko, I. Z. de Jong, J. K. Devenish, N. E. Diwan, M. V. Dorman, M. Erwin, A. R. and Escobar, C. O. Evans, J. J. Falk, E. Feldman, G. J. and Frohne, M. V. Gallagher, H. R. Godley, A. Goodman, M. C. and Gouffon, P. Gran, R. Grashorn, E. W. Grzelak, K. Habig, A. Harris, D. Harris, P. G. Hartnell, J. Hatcher, R. and Heller, K. Himmel, A. Holin, A. Hylen, J. Irwin, G. M. and Isvan, Z. Jaffe, D. E. James, C. Jensen, D. Kafka, T. Kasahara, S. M. S. Kim, J. J. Koizumi, G. Kopp, S. and Kordosky, M. Koskinen, D. J. Krahn, Z. Kreymer, A. and Lang, K. Ling, J. Litchfield, P. J. Litchfield, R. P. and Loiacono, L. Lucas, P. Ma, J. Mann, W. A. Marshak, M. L. and Marshall, J. S. Mayer, N. McGowan, A. M. Mehdiyev, R. and Meier, J. R. Messier, M. D. Metelko, C. J. Michael, D. G. Miller, W. H. Mishra, S. R. Mitchell, J. Moore, C. D. and Morfin, J. Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. Nicholls, T. C. Ochoa-Ricoux, J. P. Oliver, W. P. Osiecki, T. and Ospanov, R. Paley, J. Paolone, V. Patterson, R. B. and Pavlovic, Z. Pawloski, G. Pearce, G. F. Petyt, D. A. and Pittam, R. Plunkett, R. K. Rahaman, A. Rameika, R. A. and Raufer, T. M. Rebel, B. Rodrigues, P. A. Rosenfeld, C. and Rubin, H. A. Ryabov, V. A. Sanchez, M. C. Saoulidou, N. and Schneps, J. Schreiner, P. Semenov, V. K. Shanahan, P. and Smart, W. Smith, C. Sousa, A. Stamoulis, P. Strait, M. and Tagg, N. Talaga, R. L. Thomas, J. Thomson, M. A. and Tinti, G. Toner, R. Tsarev, V. A. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Watabe, M. Weber, A. Webb, R. C. West, N. White, C. Whitehead, L. Wojcicki, S. G. and Wright, D. M. Yang, T. Zois, M. Zhang, K. Zwaska, R. and MINOS Collaboration
- Subjects
High Energy Physics::Experiment - Abstract
The energy dependence of the neutrino-iron and antineutrino-iron inclusive charged-current cross sections and their ratio have been measured using a high-statistics sample with the MINOS near detector exposed to the NuMI beam from the main injector at Fermilab. Neutrino and antineutrino fluxes were determined using a low hadronic energy subsample of charged-current events. We report measurements of nu-Fe ((nu) over bar - Fe) cross section in the energy range 3-50 GeV (5-50 GeV) with precision of 2%-8% (3%-9%) and their ratio which is measured with precision 2%-8%. The data set spans the region from low energy, where accurate measurements are sparse, up to the high-energy scaling region where the cross section is well understood.
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- 2010
45. New constraints on muon-neutrino to electron-neutrino transitions in MINOS
- Author
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Adamson, P. Andreopoulos, C. Auty, D. J. Ayres, D. S. and Backhouse, C. Barr, G. Bernstein, R. H. Betancourt, M. and Bhattarai, P. Bishai, M. Blake, A. Bock, G. J. Boehm, J. and Boehnlein, D. J. Bogert, D. Bower, C. Budd, S. and Cavanaugh, S. Cherdack, D. Childress, S. Choudhary, B. C. and Cobb, J. H. Coelho, J. A. B. Coleman, S. J. Corwin, L. and Cronin-Hennessy, D. Danko, I. Z. de Jong, J. K. and Devenish, N. E. Diwan, M. V. Dorman, M. Escobar, C. O. and Evans, J. J. Falk, E. Feldman, G. J. Frohne, M. V. and Gallagher, H. R. Godley, A. Goodman, M. C. Gouffon, P. and Graf, N. Gran, R. Grashorn, E. W. Grzelak, K. Habig, A. and Harris, D. Harris, P. G. Hartnell, J. Hatcher, R. and Heller, K. Himmel, A. Holin, A. Huang, X. Hylen, J. and Ilic, J. Irwin, G. M. Isvan, Z. Jaffe, D. E. James, C. and Jensen, D. Kafka, T. Kasahara, S. M. S. Koizumi, G. and Kopp, S. Kordosky, M. Krahn, Z. Kreymer, A. Lang, K. and Lefeuvre, G. Ling, J. Litchfield, P. J. Litchfield, R. P. and Loiacono, L. Lucas, P. Ma, J. Mann, W. A. Marshak, M. L. Marshall, J. S. Mayer, N. McGowan, A. M. Mehdiyev, R. Meier, J. R. Messier, M. D. Michael, D. G. Miller, W. H. Mishra, S. R. Mitchell, J. Moore, C. D. Morfin, J. and Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. Ochoa-Ricoux, J. P. and Oliver, W. P. Orchanian, M. Ospanov, R. Paley, J. Para, A. Patterson, R. B. Pawloski, G. Pearce, G. F. Petyt, D. A. Pittam, R. Plunkett, R. K. Rameika, R. A. Raufer, T. M. Rebel, B. Rodrigues, P. A. Rosenfeld, C. Rubin, H. A. and Ryabov, V. A. Sanchez, M. C. Schneps, J. Schreiner, P. and Shanahan, P. Smart, W. Smith, C. Sousa, A. Strait, M. Swain, S. Tagg, N. Talaga, R. L. Thomas, J. and Thomson, M. A. Tinti, G. Toner, R. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R. C. White, C. Whitehead, L. Wojcicki, S. G. Wright, D. M. Yang, T. and Zhang, K. Zois, M. Zwaska, R. MINOS Collaboration
- Abstract
This paper reports results from a search for nu(mu) -> nu(e) transitions by the MINOS experiment based on a 7 x 10(20) protons-on-target exposure. Our observation of 54 candidate nu(e) events in the far detector with a background of 49.1 +/- 7.0(stat) +/- 2.7(syst) events predicted by the measurements in the near detector requires 2sin(2)(2 theta(13))sin(2)theta(23) < 0.12(0.20) at the 90% C.L. for the normal (inverted) mass hierarchy at delta(CP) = 0. The experiment sets the tightest limits to date on the value of theta(13) for nearly all values of delta(CP) for the normal neutrino mass hierarchy and maximal sin(2)(2 theta(23)).
- Published
- 2010
46. Search for lorentz invariance and CPT violation with the MINOS Far detector
- Author
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Adamson, P. Auty, D.J. Ayres, D.S. Backhouse, C. Barr, G. Barrett, W.L. Bishai, M. Blake, A. Bock, G.J. Boehnlein, D.J. Bogert, D. Bower, C. Budd, S. Cavanaugh, S. Cherdack, D. Childress, S. Choudhary, B.C. Coelho, J.A.B. Cobb, J.H. Coleman, S.J. Corwin, L. Cravens, J.P. Cronin-Hennessy, D. Danko, I.Z. De Jong, J.K. Devenish, N.E. Diwan, M.V. Dorman, M. Escobar, C.O. Evans, J.J. Falk, E. Feldman, G.J. Frohne, M.V. Gallagher, H.R. Gomes, R.A. Goodman, M.C. Gouffon, P. Gran, R. Grant, N. Grzelak, K. Habig, A. Harris, D. Harris, P.G. Hartnell, J. Hatcher, R. Himmel, A. Holin, A. Huang, X. Hylen, J. Ilic, J. Irwin, G.M. Isvan, Z. Jaffe, D.E. James, C. Jensen, D. Kafka, T. Kasahara, S.M.S. Koizumi, G. Kopp, S. Kordosky, M. Krahn, Z. Kreymer, A. Lang, K. Lefeuvre, G. Ling, J. Litchfield, P.J. Loiacono, L. Lucas, P. Mann, W.A. Marshak, M.L. Mayer, N. McGowan, A.M. Mehdiyev, R. Meier, J.R. Messier, M.D. Michael, D.G. Miller, J.L. Miller, W.H. Mishra, S.R. Mitchell, J. Moore, C.D. Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J.K. Newman, H.B. Nichol, R.J. Oliver, W.P. Orchanian, M. Paley, J. Patterson, R.B. Patzak, T. Pawloski, G. Pearce, G.F. Pittam, R. Plunkett, R.K. Ratchford, J. Raufer, T.M. Rebel, B. Rodrigues, P.A. Rosenfeld, C. Rubin, H.A. Ryabov, V.A. Sanchez, M.C. Saoulidou, N. Schneps, J. Schreiner, P. Semenov, V.K. Shanahan, P. Smart, W. Sousa, A. Strait, M. Tagg, N. Talaga, R.L. Thomas, J. Thomson, M.A. Tinti, G. Toner, R. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Weber, A. Webb, R.C. White, C. Whitehead, L. Wojcicki, S.G. Wright, D.M. Yang, T. Zois, M. Zwaska, R.
- Subjects
Physics::Instrumentation and Detectors ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
We searched for a sidereal modulation in the MINOS far detector neutrino rate. Such a signal would be a consequence of Lorentz and CPT violation as described by the standard-model extension framework. It also would be the first detection of a perturbative effect to conventional neutrino mass oscillations. We found no evidence for this sidereal signature, and the upper limits placed on the magnitudes of the Lorentz and CPT violating coefficients describing the theory are an improvement by factors of 20-510 over the current best limits found by using the MINOS near detector. © 2010 The American Physical Society.
- Published
- 2010
47. Search for muon-Neutrino to electron-Neutrino transitions in MINOS
- Author
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Adamson, P. Andreopoulos, C. Arms, K.E. Armstrong, R. Auty, D.J. Ayres, D.S. Backhouse, C. Barnes, P.D. Barr, G. Barrett, W.L. Becker, B.R. Belias, A. Bernstein, R.H. Betancourt, M. Bhattacharya, D. Bishai, M. Blake, A. Bock, G.J. Boehm, J. Boehnlein, D.J. Bogert, D. Bower, C. Cavanaugh, S. Chapman, J.D. Cherdack, D. Childress, S. Choudhary, B.C. Cobb, J.H. Coelho, J.A.B. Coleman, S.J. Cronin-Hennessy, D. Culling, A.J. Danko, I.Z. De Jong, J.K. Devenish, N.E. Diwan, M.V. Dorman, M. Erwin, A.R. Escobar, C.O. Evans, J.J. Falk, E. Feldman, G.J. Frohne, M.V. Gallagher, H.R. Godley, A. Goodman, M.C. Gouffon, P. Gran, R. Grashorn, E.W. Grzelak, K. Habig, A. Harris, D. Harris, P.G. Hartnell, J. Hatcher, R. Heller, K. Himmel, A. Holin, A. Howcroft, C. Huang, X. Hylen, J. Irwin, G.M. Isvan, Z. Jaffe, D.E. James, C. Jensen, D. Kafka, T. Kasahara, S.M.S. Koizumi, G. Kopp, S. Kordosky, M. Koskinen, D.J. Krahn, Z. Kreymer, A. Lang, K. Ling, J. Litchfield, P.J. Litchfield, R.P. Loiacono, L. Lucas, P. Ma, J. Mann, W.A. Marshak, M.L. Marshall, J.S. Mayer, N. McGowan, A.M. Mehdiyev, R. Meier, J.R. Messier, M.D. Metelko, C.J. Michael, D.G. Miller, W.H. Mishra, S.R. Mitchell, J. Moore, C.D. Morfín, J. Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J.K. Newman, H.B. Nichol, R.J. Nicholls, T.C. Ochoa-Ricoux, J.P. Oliver, W.P. Ospanov, R. Paley, J. Para, A. Patterson, R.B. Patzak, T. Pavlović, Ž. Pawloski, G. Pearce, G.F. Petyt, D.A. Pittam, R. Plunkett, R.K. Rahaman, A. Rameika, R.A. Raufer, T.M. Rebel, B. Reichenbacher, J. Rodrigues, P.A. Rosenfeld, C. Rubin, H.A. Ryabov, V.A. Sanchez, M.C. Saoulidou, N. Schneps, J. Schreiner, P. Shanahan, P. Smart, W. Smith, C. Sousa, A. Speakman, B. Stamoulis, P. Strait, M. Tagg, N. Talaga, R.L. Thomas, J. Thomson, M.A. Thron, J.L. Tinti, G. Toner, R. Tsarev, V.A. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Ward, D.R. Watabe, M. Weber, A. Webb, R.C. West, N. White, C. Whitehead, L. Wojcicki, S.G. Wright, D.M. Yang, T. Zhang, K. Zheng, H. Zois, M. Zwaska, R.
- Abstract
This Letter reports on a search for νμ→νe transitions by the MINOS experiment based on a 3.14×1020 protons-on-target exposure in the Fermilab NuMI beam. We observe 35 events in the Far Detector with a background of 27±5(stat)±2(syst) events predicted by the measurements in the Near Detector. If interpreted in terms of νμ→νe oscillations, this 1.5σ excess of events is consistent with sin 2(2θ13) comparable to the CHOOZ limit when |Δm2|=2.43×10-3eV2 and sin 2(2θ23)=1.0 are assumed. © 2009 The American Physical Society.
- Published
- 2009
48. Sudden stratospheric warmings seen in MINOS deep underground muon data
- Author
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Osprey, S. Barnett, J. Smith, J. Adamson, P. Andreopoulos, C. Arms, K.E. Armstrong, R. Auty, D.J. Ayres, D.S. Baller, B. Barnes Jr., P.D. Barr, G.D. Barrett, W.L. Becker, B.R. Belias, A. Bernstein, R.H. Bhattacharya, D. Bishai, M. Blake, A. Bock, G.J. Boehm, J. Boehnlein, D.J. Bogert, D. Bower, C. Buckley-Geer, E. Cavanaugh, S. Chapman, J.D. Cherdack, D. Childress, S. Choudhary, B.C. Cobb, J.H. Coleman, S.J. Culling, A.J. De Jong, J.K. Dierckxsens, M. Diwan, M.V. Dorman, M. Dytman, S.A. Escobar, C.O. Evans, J.J. Falk, E. Feldman, G.J. Frohne, M.V. Gallagher, H.R. Godley, A. Goodman, M.C. Gouffon, P. Gran, R. Grashorn, E.W. Grossman, N. Grzelak, K. Habig, A. Harris, D. Harris, P.G. Hartnell, J. Hatcher, R. Himmel, A. Holin, A. Hylen, J. Irwin, G.M. Ishitsuka, M. Jaffe, D.E. James, C. Jensen, D. Kafka, T. Kasahara, S.M.S. Kim, J.J. Koizumi, G. Kopp, S. Kordosky, M. Koskinen, D.J. Kreymer, A. Kumaratunga, S. Lang, K. Ling, J. Litchfield, P.J. Litchfield, R.P. Loiacono, L. Lucas, P. Ma, J. Mann, W.A. Marshak, M.L. Marshall, J.S. Mayer, N. McGowan, A.M. Meier, J.R. Messier, M.D. Metelko, C.J. Michael, D.G. Miller, L. Miller, W.H. Mishra, S.R. Moore, C.D. Morfin, J.G. Mualem, L. Mufson, S. Musser, J. Naples, D. Nelson, J.K. Newman, H.B. Nichol, R.J. Nicholls, T.C. Ochoa-Ricoux, J.P. Oliver, W.P. Ospanov, R. Paley, J. Paolone, V. Pavlovic, Z. Pawloski, G. Pearce, G.F. Peck, C.W. Petyt, D.A. Pittam, R. Plunkett, R.K. Rahaman, A. Rameika, R.A. Raufer, T.M. Rebel, B. Reichenbacher, J. Rodrigues, P.A. Rosenfeld, C. Rubin, H.A. Ruddick, K. Sanchez, M.C. Saoulidou, N. Schneps, J. Schreiner, P. Seun, S.M. Shanahan, P. Smart, W. Smith, C. Smith, R. Sousa, A. Speakman, B. Stamoulis, P. Strait, M. Symes, P. Tagg, N. Talaga, R.L. Tavera, M.A. Thomas, J. Thompson, J. Thomson, M.A. Thron, J.L. Tinti, G. Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Watabe, M. Weber, A. Webb, R.C. Wehmann, A. West, N. White, C. Wojcicki, S.G. Wright, D.M. Yang, T. Zhang, K. Zwaska, R.
- Abstract
The rate of high energy cosmic ray muons as measured underground is shown to be strongly correlated with upper-air temperatures during short-term atmospheric (10-day) events. The effects are seen by correlating data from the MINOS underground detector and temperatures from the European Centre for Medium Range Weather Forecasts during the winter periods from 2003-2007. This effect provides an independent technique for the measurement of meteorological conditions and presents a unique opportunity to measure both short and long-term changes in this important part of the atmosphere. Copyright 2009 by the American Geophysical Union.
- Published
- 2009
49. Study of muon neutrino disappearance using the Fermilab Main Injector neutrino beam
- Author
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Adamson, P. Andreopoulos, C. Arms, K. E. Armstrong, R. and Auty, D. J. Avvakumov, S. Ayres, D. S. Baller, B. and Barish, B. Barnes, Jr., P. D. Barr, G. Barrett, W. L. and Beall, E. Becker, B. R. Belias, A. Bernstein, R. H. and Bhattacharya, D. Bishai, M. Blake, A. Bock, B. Bock, G. J. Boehm, J. Boehnlein, D. J. Bogert, D. Border, P. M. and Bower, C. Buckley-Geer, E. Cabrera, A. Cavanaugh, S. and Chapman, J. D. Cherdack, D. Childress, S. Choudhary, B. C. and Cobb, J. H. Coleman, S. J. Culling, A. J. De Jong, J. K. and Dierckxsens, M. Diwan, M. V. Dorman, M. Drakoulakos, D. and Durkin, T. Dytman, S. A. Erwin, A. R. Escobar, C. O. and Evans, J. J. Harris, E. Falk Feldman, G. J. Fields, T. H. and Ford, R. Frohne, M. V. Gallagher, H. R. Godley, A. and Gogos, J. Goodman, M. C. Gouffon, P. Gran, R. Grashorn, E. W. Grossman, N. Grzelak, K. Habig, A. Harris, D. and Harris, P. G. Hartnell, J. Hartouni, E. P. Hatcher, R. and Heller, K. Himmel, A. Holin, A. Howcroft, C. Hylen, J. and Indurthy, D. Irwin, G. M. Ishitsuka, M. Jaffe, D. E. and James, C. Jenner, L. Jensen, D. Kafka, T. Kang, H. J. and Kasahara, S. M. S. Kim, M. S. Koizumi, G. Kopp, S. and Kordosky, M. Koskinen, D. J. Kotelnikov, S. K. Kreymer, A. and Kumaratunga, S. Lang, K. Lebedev, A. Lee, R. Ling, J. Liu, J. Litchfield, P. J. Litchfield, R. P. Loiacono, L. Lucas, P. Mann, W. A. Marchionni, A. Marino, A. D. and Marshak, M. L. Marshall, J. S. Mayer, N. McGowan, A. M. and Meier, J. R. Merzon, G. I. Messier, M. D. Metelko, C. J. and Michael, D. G. Milburn, R. H. Miller, J. L. Miller, W. H. Mishra, S. R. Mislivec, A. Moore, C. D. Morfin, J. and Mualem, L. Mufson, S. Murgia, S. Musser, J. Naples, D. Nelson, J. K. Newman, H. B. Nichol, R. J. Nicholls, T. C. Ochoa-Ricoux, J. P. Oliver, W. P. Osiecki, T. and Ospanov, R. Paley, J. Paolone, V. Para, A. Patzak, T. and Pavlovic, Z. Pearce, G. F. Peck, C. W. Peterson, E. A. and Petyt, D. A. Ping, H. Pittam, R. Plunkett, R. K. and Rahman, D. Rameika, R. A. Raufer, T. M. Rebel, B. and Reichenbacher, J. Reyna, D. E. Rodrigues, P. A. Rosenfeld, C. Rubin, H. A. Ruddick, K. Ryabov, V. A. Saakyan, R. and Sanchez, M. C. Saoulidou, N. Schneps, J. Schreiner, P. and Semenov, V. K. Seun, S. -M. Shanahan, P. Smart, W. and Smirnitsky, V. Smith, C. Sousa, A. Speakman, B. and Stamoulis, P. Strait, M. Symes, P. A. Tagg, N. Talaga, R. L. Tetteh-Lartey, E. Thomas, J. Thompson, J. Thomson, M. A. Thron, J. L. Tinti, G. Trostin, I. Tsarev, V. A. and Tzanakos, G. Urheim, J. Vahle, P. Verebryusov, V. and Viren, B. Ward, C. P. Ward, D. R. Watabe, M. Weber, A. and Webb, R. C. Wehmann, A. West, N. White, C. Wojcicki, S. G. Wright, D. M. Yang, T. Zheng, H. Zois, M. and Zwaska, R. Minos Collaboration
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Physics::Instrumentation and Detectors ,High Energy Physics::Experiment - Abstract
We report the results of a search for nu(mu) disappearance by the Main Injector Neutrino Oscillation Search [D. G. Michael (MINOS), Phys. Rev. Lett. 97, 191801 (2006).]. The experiment uses two detectors separated by 734 km to observe a beam of neutrinos created by the Neutrinos at the Main Injector facility at Fermi National Accelerator Laboratory. The data were collected in the first 282 days of beam operations and correspond to an exposure of 1.27x10(20) protons on target. Based on measurements in the Near Detector, in the absence of neutrino oscillations we expected 336 +/- 14 nu(mu) charged-current interactions at the Far Detector but observed 215. This deficit of events corresponds to a significance of 5.2 standard deviations. The deficit is energy dependent and is consistent with two-flavor neutrino oscillations according to |Delta m(2)|=2.74(-0.26)(+0.44) x 10(-3) eV(2)/c(4) and sin(2)2 theta > 0.87 at 68% confidence level.
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- 2008
50. Measurement of neutrino oscillations with the MINOS detectors in the NuMI beam
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Adamson, P. Andreopoulos, C. Arms, K. E. Armstrong, R. and Auty, D. J. Ayres, D. S. Baller, B. Barnes, Jr., P. D. and Barr, G. Barrett, W. L. Becker, B. R. Belias, A. and Bernstein, R. H. Bhattacharya, D. Bishai, M. Blake, A. and Bock, G. J. Boehm, J. Boehnlein, D. J. Bogert, D. Bower, C. Buckley-Geer, E. Cavanaugh, S. Chapman, J. D. and Cherdack, D. Childress, S. Choudhary, B. C. Cobb, J. H. and Coleman, S. J. Culling, A. J. de Jong, J. K. Dierckxsens, M. and Diwan, M. V. Dorman, M. Dytman, S. A. Escobar, C. O. and Evans, J. J. Harris, E. Falk Feldman, G. J. Frohne, M. V. and Gallagher, H. R. Godley, A. Goodman, M. C. Gouffon, P. and Gran, R. Grashorn, E. W. Grossman, N. Grzelak, K. and Habig, A. Harris, D. Harris, P. G. Hartnell, J. Hatcher, R. Heller, K. Himmel, A. Holin, A. Hylen, J. Irwin, G. M. Ishitsuka, M. Jaffe, D. E. James, C. Jensen, D. and Kafka, T. Kasahara, S. M. S. Kim, J. J. Kim, M. S. and Koizumi, G. Kopp, S. Kordosky, M. Koskinen, D. J. and Kotelnikov, S. K. Kreymer, A. Kumaratunga, S. Lang, K. and Ling, J. Litchfield, P. J. Litchfield, R. P. Loiacono, L. and Lucas, P. Ma, J. Mann, W. A. Marchionni, A. Marshak, M. L. Marshall, J. S. Mayer, N. McGowan, A. M. Meier, J. R. Merzon, G. I. Messier, M. D. Metelko, C. J. Michael, D. G. Miller, J. L. Miller, W. H. Mishra, S. R. Moore, C. D. Morfin, J. Mualem, L. Mufson, S. Murgia, S. and Musser, J. Naples, D. Nelson, J. K. Newman, H. B. and Nichol, R. J. Nicholls, T. C. Ochoa-Ricoux, J. P. Oliver, W. P. Ospanov, R. Paley, J. Paolone, V. Para, A. and Patzak, T. Pavlovic, Z. Pawloski, G. Pearce, G. F. Peck, C. W. Peterson, E. A. Petyt, D. A. Pittam, R. Plunkett, R. K. Rahaman, A. Rameika, R. A. Raufer, T. M. Rebel, B. and Reichenbacher, J. Rodrigues, P. A. Rosenfeld, C. Rubin, H. A. Ruddick, K. Ryabov, V. A. Sanchez, M. C. and Saoulidou, N. Schneps, J. Schreiner, P. Seun, S. -M. and Shanahan, P. Smart, W. Smith, C. Sousa, A. Speakman, B. and Stamoulis, P. Strait, M. Symes, P. Tagg, N. Talaga, R. L. Tavera, M. A. Thomas, J. Thompson, J. Thomson, M. A. Thron, J. L. Tinti, G. Trostin, I. Tsarev, V. A. and Tzanakos, G. Urheim, J. Vahle, P. Viren, B. Ward, C. P. and Ward, D. R. Watabe, M. Weber, A. Webb, R. C. and Wehmann, A. West, N. White, C. Wojcicki, S. G. Wright, D. M. Yang, T. Zois, M. Zhang, K. Zwaska, R. MINOS Collaboration
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Physics::Instrumentation and Detectors ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment - Abstract
This Letter reports new results from the MINOS experiment based on a two-year exposure to muon neutrinos from the Fermilab NuMI beam. Our data are consistent with quantum-mechanical oscillations of neutrino flavor with mass splitting vertical bar Delta m(2)vertical bar = (2.43 +/- 0.13) x 10(-3) eV(2) (68% C.L.) and mixing angle sin(2)(2 theta) > 0.90 (90% C.L.). Our data disfavor two alternative explanations for the disappearance of neutrinos in flight: namely, neutrino decays into lighter particles and quantum decoherence of neutrinos, at the 3.7 and 5.7 standard-deviation levels, respectively.
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- 2008
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