Search

Your search keyword '"Donnelly, S. C."' showing total 232 results
Start Over Author "Donnelly, S. C."
232 results on '"Donnelly, S. C."'

18. Irish thoracic society: Proceedings of annual scientific meeting held in Cork on 5th & 6th November, 1993

Author

Chan, K. H., Singh, H. P., Aherne, T., Carabine, U., Gilliland, H., Johnston, J. R., Lowry, K. G., McGuigan, J., Cosgrove, J., Veerasingham, D., McCarthy, J., Hurley, J., Wood, A. E., Gilliland, R., McGuigan, J. A., McManus, K. G., Wilkinson, P., Johnston, L. C., MacMahon, J., Wilson, D., Austin, C., Anikin, V., McManus, K., McGuigan, J., McManus, K., Anikin, V., Gibbons, J. R. P., McGuigan, J., Sharkey, R., Long, M., Maree, A., O’Neill, S., Maguire, C. P., Hayes, J. P., Masterson, J., Fitzgerald, M. X., Hayes, M., Maguire, C. P., Hayes, J. P., Masterson, J., Fitzgerald, M. X., Quigley, C., Mofidi, A., Mofidi, R., Fitzgerald, M. X., O’Neill, M., Watson, J. B. G., O’Halloran, E. T., Shortt, C., Taylor, M., Holland, C., O’Lorcain, P., Taylor, M., Holland, C., O’Lorcain, P., Pathmakanthan, S., Sreenan, S., Power, C. K., Poulter, L. W., Burke, C. M., Reilly, D., Pathmakanthan, S., Sreenan, S., Doyle, S., Burke, C. M., Sreenan, S., Power, C., Pathmakanthan, S., Goggin, A., Burke, C. M., Poulter, L. W., Sreenan, S., Doyle, S., Pathmakanthan, S., Poulter, L. W., Burke, C. M., Sreenan, S., Debenham, P., Pathmakanthan, S., Burke, C. M., Poulter, L. W., Southey, A., O’Connor, C. M., Fitzgerald, M. X., Bourke, W. J., McDonnell, T. J., Buck, J. B., Magee, T. R. A., Lowry, R. C., Graham, A. N. J., Owens, W. A., Kelly, S. B., McGuigan, J. A., Costelloe, R. W., Ryan, J., Collins, J., Guerin, D., Rooney, D., Long, E., O’Donnell, M., O’Neill, S., Cotter, T. P., Bredin, C. P., Buick, J. B., Lowry, R. C., MacMahon, J. J., Finlay, G., Concannon, D., McDonnell, T. J., Reid, P. T., Alderdice, J., Carson, J., Sinnamon, D. G., Murphy, S., Scott, T., Keane, C. T., Walsh, J. B., Coakley, D., McKeown, D., Kelly, P., Clancy, L., Kiely, J. L., Cryan, B., Bredin, C. P., Killeen, P., Farrell, S., Kelly, P., Clancy, L., Kiely, J. L., O’Riordan, D. M., Sheehan, S., Curtain, J., Hogan, J., Bredin, C. P., Malone, A., Ahmed, S., Watson, J. B. G., Murphy, M., Fennell, W., Ahmed, S., Watson, J. B. G., Aherne, T., Keohane, C., O’Neill, M., Gleeson, C. M., McGuigan, J., Ritchie, A. J., Russell, S. E. H., Molloy, E., Keane, M., Coakley, R., Costello, R., Condron, C., Watson, R. G. W., O’Neill, S., Kelly, C., Redmond, H., Watson, W., Burke, P., Bouchier-Hayes, D., Donnelly, S. C., Haslett, C., Dransfield, I., Robertson, C. E., Carter, D. C., Ross, J. A., Grant, I. S., Tedder, T. F., Doyle, S., Sreenan, S., Pathmakanthan, S., Burke, C. M., Heaney, L. G., Cross, L. J. M., Stanford, C. F., Ennis, Madeleine, Sreenan, S., Pathmakanthan, S., Power, C., Goggin, A., Poulter, L. W., Burke, C. M., Murphy, S., Scott, T., Keane, C. T., Walsh, J. B., Coakley, D., O’Riordan, D. M., Gergely, L., Deng, N., Rose, R. M., Hennessy, T., Hickey, L., Thornton, L., Collum, C., Durity, M., Power, J., Johnson, H., Lee, B., Doherty, E., Kelly, E., McDonnell, T., McKeown, D., Kelly, P., Clancy, L., Wilkinson, P., Varghese, G., Anikin, V., Gibbons, J., McManus, K., McGuigan, J., Reid, P. T., Gower, N. H., and Rudd, R. M.

Published
1994
Full Text
View/download PDF

19. Irish thoracic society: Proceedings of Annual Meeting held in Galway on November 6th & 7th, 1992

Author

Quigley, C., Mofidi, R., Liu, G., O’Connor, C., FitzGerald, M. X., Johnson, H., MacDonnell, T., Lee, B., Kelly, E., Doherty, E., McCarthy, J. F., Hurley, J., Wood, A. E., Lynch, V. P., Ellias, E., Tahir, M., Asad Ali, S., Istarabadi, M., Hussain, R., McGovern, Ms. E., Luke, D. A., Murphy, M., Mealy, K., Little, D., Burke, P., O’Neill, S., Broe, P., Guidon, M., Long, M., Reid, P. T., MacMahon, J., Babu, M. V. S., Watson, J. B. G., O’Halloran, E. T., Kumar, P., Shortt, C., Murphy, S., Hegarty, V., Scott, T., Keane, C. T., Walsh, J. B., Coakley, D., Clancy, L., Corcoran, P., Kelly, P., Healy, T., Moore, H., Cormican, M., Flynn, J., Gilmartin, J. J., O’Connor, H., Power, W., McNicholas, N., Lindsay, P. J., Noone, D., Glennon, M., Smith, T., Gannon, F., O’Dwyer, R., Stack, N., Kyne, K., McHale, E., Sidhu, P., O’ Sullivan, R., Callaghan, J., Wilkinson, P., McKenzie, G., O’Connor, C. M., Ryan, M., Shanahan, P., O’Donnel, N., Conlon, P., O’Neill, G., Long, H., Carmody, M., Keogh, B., Donohoe, J., Walshe, J., Lyons, D. J., Madrigal, L., Luke, D., McKinley, R. K., Jamison, J. P., Sreenan, S. K., Power, C. K., Pathmakanthan, S., Burke, C. M., Poulter, L. W., O’Donovan, D. A., Bouchier-Hayes, D. M., Kelly, C., Grace, P., Redmond, H. P., Monkhouse, W. S., Bouchier-Hayes, D., Bourke, W. J., McDonnell, T. J., Cotter, T. P., Bredin, C. P., Hayes, J. P., Ward, K., Muldowney, F., Othman, S., Conroy, R., Collum, C., Durity, M., Power, J., Gaffney, K., Southey, A., Keane, J., Byrne, N., Hayes, J., Magee, T. R. A., Buick, J. B., Lowry, R. C., Kelly, C. J., Shou, J., Gallagher, H., Daly, J. M., Bouchier-Hayes, D, Donnelly, S. C., Haslett, C., Grant, I. S., Streiter, R. M., Kunkel, S. L., Walz, A., Robertson, C. R., Carter, D. C., Pollock, A. J., O’Neill, M., Dockrell, D., Rooney, M., Memon, I., Loftus, B. G., Mulcahy, R., Periappuram, Murphy, P., Mulroy, Sr. M., Taylor, M. R. H., Costello, R., McNicholas, W. T., Watson, R. G. W., and O’Neill, S. J.

Published
1993
Full Text
View/download PDF

30. Exploring the barriers and facilitators for the use of digital health technologies for the management of COPD: a qualitative study of clinician perceptions.

Author

Slevin, P, Kessie, T, Cullen, J, Butler, M W, Donnelly, S C, and Caulfield, B

Subjects
OBSTRUCTIVE lung diseases, MEDICAL technology, TECHNOLOGY management, DIGITAL technology, MEDICAL personnel
Abstract

Background Digital health technology (DHT) promises to support patients and healthcare professionals (HCPs) to optimize the management of chronic obstructive pulmonary disease (COPD). However, there is a lack of evidence demonstrating the effectiveness of DHT for the management of COPD. One reason for this is the lack of user-involvement in the development of DHT interventions in COPD meaning their needs and preferences are rarely accounted for in the design phase. Although HCP adoption issues have been identified in relation to DHT, little is known about the challenges perceived by HCPs providing care to COPD patients. Therefore, this study aims to qualitatively explore the barriers and facilitators HCPs perceive for the use of DHT in the management of COPD. Methods Participants (n = 32) were recruited using snowball sampling from two university hospitals and several general practitioner clinics. A semi-structured interview was conducted with each participant. NVivo 12 software was used to complete thematic analysis on the data. Results Themes identified include: data quality; evidence-based care; resource constraints; and digital literacy presented as barriers; and facilitators include the following themes: digital health training and education; improving HCP digital literacy; and Personalized prescribing. Patient-centered approaches, such as pulmonary rehabilitation and shared decision-making were suggested as implementation strategies to ease the adoption of digital health for the management of COPD. Conclusion These findings contribute new insights about the needs and preferences of HCPs working in COPD regarding DHT. The findings can be used to help mitigate user-experience issues by informing the design of person-centered implementation and adoption strategies for future digital health interventions in COPD. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

37. Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis

Author

Cooke, G, primary, Kamal, I, additional, Strengert, M, additional, Hams, E, additional, Mawhinney, L, additional, Tynan, A, additional, O’Reilly, C, additional, O’Dwyer, D N, additional, Kunkel, S L, additional, Knaus, U G, additional, Shields, D C, additional, Moller, D R, additional, Bowie, A G, additional, Fallon, P G, additional, Hogaboam, C M, additional, Armstrong, M E, additional, and Donnelly, S C, additional

Published
2017
Full Text
View/download PDF

41. The lady with the dragon tattoo

Author

O’Beirne, S. L., primary, O’Dwyer, D. N., additional, Walsh, S. M., additional, Dodd, J. D., additional, Crotty, T. B., additional, and Donnelly, S. C., additional

Published
2016
Full Text
View/download PDF

42. Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis.

Author

Kunkel, S. L., Cooke, G., Strengert, M., O'Dwyer, D. N., Knaus, U. G., Kamal, I., Hams, E., Mawhinney, L., Tynan, A., O'Reilly, C., Armstrong, M. E., Donnelly, S. C., Fallon, P. G., Shields, D. C., Moller, D. R., Bowie, A. G., and Hogaboam, C. M.

Subjects
SARCOIDOSIS, TOLL-like receptors, GENETIC polymorphisms, PHENOTYPES, ETIOLOGY of diseases, GRANULOMA, GENETICS
Abstract

Background/Introduction: Sarcoidosis is a multi-systemic disorder of unknown etiology, characterized by the presence of non-caseating granulomas in target organs. In 90% of cases, there is thoracic involvement. Fifty to seventy percent of pulmonary sarcoidosis patients will experience acute, self-limiting disease. For the subgroup of patients who develop persistent disease, no targeted therapy is currently available. Aim: To investigate the potential of the single nucleotide polymorphism (SNP), Toll-like receptor 3 Leu412Phe (TLR3 L412F; rs3775291), as a causative factor in the development of and in disease persistence in pulmonary sarcoidosis. To investigate the functionality of TLR3 L412F in vitro in primary human lung fibroblasts from pulmonary sarcoidosis patients. Design: SNP-genotyping and cellular assays, respectively, were used to investigate the role of TLR3 L412F in the development of persistent pulmonary sarcoidosis. Methods: Cohorts of Irish sarcoidosis patients (n=228), healthy Irish controls (n=263) and a secondary cohort of American sarcoidosis patients (n=123) were genotyped for TLR3 L412F. Additionally, the effect of TLR3 L412F in primary lung fibroblasts from pulmonary sarcoidosis patients was quantitated following TLR3 activation in the context of cytokine and type I interferon production, TLR3 expression and apoptotic- and fibroproliferative-responses. Results: We report a significant association between TLR3 L412F and persistent clinical disease in two cohorts of Irish and American Caucasians with pulmonary sarcoidosis. Furthermore, activation of TLR3 in primary lung fibroblasts from 412 Fhomozygous pulmonary sarcoidosis patients resulted in reduced IFN-β and TLR3 expression, reduced apoptosis- and dysregulated fibroproliferative-responses compared with TLR3 wild-type patients. Discussion/Conclusion: This study identifies defective TLR3 function as a previously unidentified factor in persistent clinical disease in pulmonary sarcoidosis and reveals TLR3 L412F as a candidate biomarker. [ABSTRACT FROM AUTHOR]

Published
2018
Full Text
View/download PDF

47. Long COVID syndrome and the lung: how long will it last?

Author

Mitchell, P D, Olaniyi, J, Buckley, C, and Donnelly, S C

Subjects
POST-acute COVID-19 syndrome, COVID-19, PULMONARY function tests, SYNDROMES, LUNGS
Abstract

The prevalence and duration of the long-term respiratory complications of COVID-19 infection remains to be elucidated. This short commentary reports on recently published studies in patients post-acute COVID-19 infection in terms of symptom prevalence, physiological and radiological sequela and where only symptoms are present despite investigation. Pulmonary function testing, 6-min walk tests, computed tomography chest and more advanced imaging modalities have been incorporated to reveal the underlying pathophysiology that cause such disabling symptoms in patient with post-acute COVID-9 syndrome (PACS). PACS has a serious impact on people's ability to return to work, affecting the physical, mental, social sphere and with significant healthcare and general economic consequences for them, their families and society. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

49. Sarcoidosis, alveolar -actin and pulmonary fibrosis

Author

Cooke, G., primary, Govender, P., additional, Watson, C. J., additional, Armstrong, M. E., additional, O'Dwyer, D. N., additional, Keane, M. P., additional, King, R., additional, Tynan, A., additional, Dunn, M., additional, and Donnelly, S. C., additional

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results