246 results on '"Donker D."'
Search Results
2. Advanced waveform analysis of diaphragm surface EMG allows for continuous non-invasive assessment of respiratory effort in critically ill patients at different PEEP levels
- Author
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Warnaar, R. S. P., Cornet, A. D., Beishuizen, A., Moore, C. M., Donker, D. W., and Oppersma, E.
- Published
- 2024
- Full Text
- View/download PDF
3. Computational physiological models for individualised mechanical ventilation: a systematic literature review focussing on quality, availability, and clinical readiness
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Warnaar, R. S. P., Mulder, M. P., Fresiello, L., Cornet, A. D., Heunks, L. M. A., Donker, D. W., and Oppersma, E.
- Published
- 2023
- Full Text
- View/download PDF
4. Cardiac tamponade during venoarterial extracorporeal membrane oxygenation: a case report
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Adriaansen, E. J. M., Hermens, J. A. J., Broome, M., Pladet, L., Dubois, E., Donker, D. W., and Meuwese, C. L.
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- 2023
- Full Text
- View/download PDF
5. Clinical decision making for VA ECMO weaning in patients with cardiogenic shock A formative qualitative study
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Hermens, J. A. J., primary, van Til, J. A., additional, Meuwese, C. L., additional, van Dijk, D., additional, and Donker, D. W., additional
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- 2024
- Full Text
- View/download PDF
6. Twelve years of circulatory extracorporeal life support at the University Medical Centre Utrecht
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Meuwese, C. L., Hermens, J. A., de Haan, M., Braithwaite, S. A., Ramjankhan, F., Buijsrogge, M. P., de Jonge, N., Kirkels, J. H., de Jong, M., Pasma, W., Vromen-Wijsman, J. L. P., Kraaijeveld, A. O., de Waal, E. E., Torn, E., Platenkamp, M., van der Heijden, J. J., Cremer, O. L., van Dijk, D., and Donker, D. W.
- Published
- 2021
- Full Text
- View/download PDF
7. Left Ventricular Unloading in Extracorporeal Membrane Oxygenation: A Clinical Perspective Derived from Basic Cardiovascular Physiology
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Medische Staf Intensive Care, Other research (not in main researchprogram), Protti, I., van Steenwijk, M. P.J., Meani, P., Fresiello, L., Meuwese, C. L., Donker, D. W., Medische Staf Intensive Care, Other research (not in main researchprogram), Protti, I., van Steenwijk, M. P.J., Meani, P., Fresiello, L., Meuwese, C. L., and Donker, D. W.
- Published
- 2024
8. Clinical evidence and technical aspects of innovative technology and monitoring of chronic NIV in COPD: a narrative review
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Medische Staf Intensive Care, Other research (not in main researchprogram), Soleimani, F, Donker, D W, Oppersma, E, Duiverman, M L, Medische Staf Intensive Care, Other research (not in main researchprogram), Soleimani, F, Donker, D W, Oppersma, E, and Duiverman, M L
- Published
- 2024
9. Left Ventricular Unloading in Extracorporeal Membrane Oxygenation:A Clinical Perspective Derived from Basic Cardiovascular Physiology
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Protti, I., van Steenwijk, M. P.J., Meani, P., Fresiello, L., Meuwese, C. L., Donker, D. W., Protti, I., van Steenwijk, M. P.J., Meani, P., Fresiello, L., Meuwese, C. L., and Donker, D. W.
- Abstract
Purpose of Review: To present an abridged overview of the literature and pathophysiological background of adjunct interventional left ventricular unloading strategies during veno-arterial extracorporeal membrane oxygenation (V-A ECMO). From a clinical perspective, the mechanistic complexity of such combined mechanical circulatory support often requires in-depth physiological reasoning at the bedside, which remains a cornerstone of daily practice for optimal patient-specific V-A ECMO care. Recent Findings: Recent conventional clinical trials have not convincingly shown the superiority of V-A ECMO in acute myocardial infarction complicated by cardiogenic shock as compared with medical therapy alone. Though, it has repeatedly been reported that the addition of interventional left ventricular unloading to V-A ECMO may improve clinical outcome. Novel approaches such as registry-based adaptive platform trials and computational physiological modeling are now introduced to inform clinicians by aiming to better account for patient-specific variation and complexity inherent to V-A ECMO and have raised a widespread interest.Summary: To provide modern high-quality V-A ECMO care, it remains essential to understand the patient's pathophysiology and the intricate interaction of an individual patient with extracorporeal circulatory support devices. Innovative clinical trial design and computational modeling approaches carry great potential towards advanced clinical decision support in ECMO and related critical care.
- Published
- 2024
10. Advanced waveform analysis of diaphragm surface EMG allows for continuous non-invasive assessment of respiratory effort in critically ill patients at different PEEP levels
- Author
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PMC Medisch specialisten, Medische Staf Intensive Care, Other research (not in main researchprogram), Warnaar, R S P, Cornet, A D, Beishuizen, A, Moore, C M, Donker, D W, Oppersma, E, PMC Medisch specialisten, Medische Staf Intensive Care, Other research (not in main researchprogram), Warnaar, R S P, Cornet, A D, Beishuizen, A, Moore, C M, Donker, D W, and Oppersma, E
- Published
- 2024
11. Clinical decision making for VA ECMO weaning in patients with cardiogenic shock A formative qualitative study
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Medische Staf Intensive Care, Brain, Other research (not in main researchprogram), Hermens, J. A.J., van Til, J. A., Meuwese, C. L., van Dijk, D., Donker, D. W., Medische Staf Intensive Care, Brain, Other research (not in main researchprogram), Hermens, J. A.J., van Til, J. A., Meuwese, C. L., van Dijk, D., and Donker, D. W.
- Published
- 2024
12. Patient-Specific Real-Time Cardiovascular Simulation as Clinical Decision Support in Intensive Care Medicine
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Broomé, M., Donker, D. W., and Vincent, Jean-Louis, editor
- Published
- 2017
- Full Text
- View/download PDF
13. Venoarterial extracorporeal membrane oxygenation in elective high-risk percutaneous coronary intervention: a viable option?
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Meuwese, C. L., Ramjankhan, F. Z., Kraaijeveld, A. O., and Donker, D. W.
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- 2020
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14. Extracorporeal life support in cardiogenic shock: indications and management in current practice
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Meuwese, C. L., Ramjankhan, F. Z., Braithwaite, S. A., de Jonge, N., de Jong, M., Buijsrogge, M. P., Janssen, J. G. D., Klöpping, C., Kirkels, J. H., and Donker, D. W.
- Published
- 2018
- Full Text
- View/download PDF
15. Using a smartwatch to record precordial electrocardiograms: a validation study
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Van Der Zande, J L, primary, Strik, M, additional, Dubois, R, additional, Ploux, S, additional, Abu-Alrub, S, additional, Donker, D W, additional, Oppersma, E, additional, and Bordachar, P, additional
- Published
- 2023
- Full Text
- View/download PDF
16. Computational physiological models for individualised mechanical ventilation:a systematic literature review focussing on quality, availability, and clinical readiness
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Warnaar, R. S.P., Mulder, M. P., Fresiello, L., Cornet, A. D., Heunks, L. M.A., Donker, D. W., Oppersma, E., Warnaar, R. S.P., Mulder, M. P., Fresiello, L., Cornet, A. D., Heunks, L. M.A., Donker, D. W., and Oppersma, E.
- Abstract
Background: Individualised optimisation of mechanical ventilation (MV) remains cumbersome in modern intensive care medicine. Computerised, model-based support systems could help in tailoring MV settings to the complex interactions between MV and the individual patient's pathophysiology. Therefore, we critically appraised the current literature on computational physiological models (CPMs) for individualised MV in the ICU with a focus on quality, availability, and clinical readiness. Methods: A systematic literature search was conducted on 13 February 2023 in MEDLINE ALL, Embase, Scopus and Web of Science to identify original research articles describing CPMs for individualised MV in the ICU. The modelled physiological phenomena, clinical applications, and level of readiness were extracted. The quality of model design reporting and validation was assessed based on American Society of Mechanical Engineers (ASME) standards. Results: Out of 6,333 unique publications, 149 publications were included. CPMs emerged since the 1970s with increasing levels of readiness. A total of 131 articles (88%) modelled lung mechanics, mainly for lung-protective ventilation. Gas exchange (n = 38, 26%) and gas homeostasis (n = 36, 24%) models had mainly applications in controlling oxygenation and ventilation. Respiratory muscle function models for diaphragm-protective ventilation emerged recently (n = 3, 2%). Three randomised controlled trials were initiated, applying the Beacon and CURE Soft models for gas exchange and PEEP optimisation. Overall, model design and quality were reported unsatisfactory in 93% and 21% of the articles, respectively. Conclusion: CPMs are advancing towards clinical application as an explainable tool to optimise individualised MV. To promote clinical application, dedicated standards for quality assessment and model reporting are essential. Trial registration number PROSPERO— CRD42022301715 . Registered 05 February, 2022.
- Published
- 2023
17. Cardiac tamponade during venoarterial extracorporeal membrane oxygenation:a case report
- Author
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Adriaansen, E. J.M., Hermens, J. A.J., Broome, M., Pladet, L., Dubois, E., Donker, D. W., Meuwese, C. L., Adriaansen, E. J.M., Hermens, J. A.J., Broome, M., Pladet, L., Dubois, E., Donker, D. W., and Meuwese, C. L.
- Abstract
Background: Cardiac tamponade may present with very different signs and clinical consequences in patients who are supported with venoarterial extracorporeal membrane oxygenation. Failure to recognize cardiac tamponade in this setting can cause failure to wean from venoarterial extracorporeal membrane oxygenation, and even lead to death. Case presentation: We present a 44-year-old Caucasian female in whom cardiac tamponade manifested as venoarterial extracorporeal membrane oxygenation weaning failure. After discovering the contribution of cardiac tamponade, it was possible to wean the patient from venoarterial extracorporeal membrane oxygenation support. No clear signs of cardiac tamponade had existed beforehand. Conclusions: The diagnosis of cardiac tamponade can be very challenging in venoarterial extracorporeal membrane oxygenation supported patients due to (patho)physiological particularities related to the parallel blood flow.
- Published
- 2023
18. Computational physiological models for individualised mechanical ventilation: a systematic literature review focussing on quality, availability, and clinical readiness
- Author
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Medische Staf Intensive Care, Other research (not in main researchprogram), Warnaar, R. S.P., Mulder, M. P., Fresiello, L., Cornet, A. D., Heunks, L. M.A., Donker, D. W., Oppersma, E., Medische Staf Intensive Care, Other research (not in main researchprogram), Warnaar, R. S.P., Mulder, M. P., Fresiello, L., Cornet, A. D., Heunks, L. M.A., Donker, D. W., and Oppersma, E.
- Published
- 2023
19. Cardiac tamponade during venoarterial extracorporeal membrane oxygenation: a case report
- Author
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Medische Staf Intensive Care, Sepsis and Inflammation, Infection & Immunity, Other research (not in main researchprogram), Cardiologie, Adriaansen, E. J.M., Hermens, J. A.J., Broome, M., Pladet, L., Dubois, E., Donker, D. W., Meuwese, C. L., Medische Staf Intensive Care, Sepsis and Inflammation, Infection & Immunity, Other research (not in main researchprogram), Cardiologie, Adriaansen, E. J.M., Hermens, J. A.J., Broome, M., Pladet, L., Dubois, E., Donker, D. W., and Meuwese, C. L.
- Published
- 2023
20. With our minds wide open: Let us foster the young academic spirit in critical care!
- Author
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Donker, D. W., Cardiovascular and Respiratory Physiology, and TechMed Centre
- Subjects
critical care ,education ,NLA ,intensive care - Published
- 2022
21. OC31 HOW TO IDENTIFY THE APPROPRIATE LEFT VENTRICULAR ASSIST DEVICE CANDIDATE AMONG PATIENTS ON EXTRACORPOREAL MEMBRANE OXYGENATION SUPPORT
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Loforte, A., Morshuis, M., Zimpfer, D., Pappalardo, F., Attisani, M., Riebandt, J., Ramjankhan, F., Donker, D., Jorde, U., Albert, A., Lichtenberg, A., Rinaldi, M., and Saeed, D.
- Published
- 2018
- Full Text
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22. ESICM LIVES 2016: part two: Milan, Italy. 1–5 October 2016
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Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Lazaridis, C., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, D. E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., van den Boogaard, M., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Moore, J., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Randall, D., Adwaney, A., Blunden, M., Prowle, J.R., Kirwan, C. J., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., Girbes, A. R. J., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Carteron, L., Patet, C., Quintard, H., Solari, D., Bouzat, P., Oddo, M., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schneider, J., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Vincent, J. L., Creteur, J., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. J., Koch, B., Rietdijk, W., Devlin, J., van der Jagt, M., Picetti, E., Ceccarelli, P., Mensi, F., Malchiodi, L., Risolo, S., Rossi, I., Antonini, M. V., Servadei, F., Caspani, M. L., Roquilly, A., Lasocki, S., Seguin, P., Geeraerts, T., Perrigault, P. F., Dahyot-Fizelier, C., Paugam-Burtz, C., Cook, F., Cinotti, R., dit Latte, D. Demeure, Mahe, P. 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Aguilera, Travierso, C., Chiurazzi, C., Motos, A., Amaro, R., Hua, Y., Fernández-Barat, L., Ranzani, O. T., Bobi, Q., Rigol, M., Torres, A., Youn, A., Hwang, J. Gyung, Garach, M. Muñoz, Romero, O. Moreno, Ossorio, M. E. Yuste, Diaz, F. Acosta, Bailon, A. M. Perez, Pinel, A. Carranza, Maldonado, L. Peñas, Teixeira, C., Figueira, H., Oliveira, R., Mota, A., Aragão, I., Kamp, O., Cruciger, O., Aach, M., Kaczmarek, C., Waydhas, C., Schildhauer, T. A., Hamsen, U., Camprubí-Rimblas, M., Chimenti, L., Guillamat-Prats, R., Lebouvier, T., Bringué, J., Tijero, J., Gómez, M. N., Blanch, L., Artigas, A., Tagliabue, G., Ji, M., Jagers, J. V. Suneby, Easton, P. A., Souza, R. B., Liberatore, A. M. A., Martins, A. M. C. R. P. F., Vieira, J. C. F., Kang, Y. R., Nakamae, M. N., Koh, I. H. J., Hong, J. Y., Shin, M. H., Park, M. S., Pomprapa, A., Pickerodt, P. A., Hofferberth, M. B. T., Russ, M., Braun, W., Walter, M., Francis, R., Lachmann, B., Leonhardt, S., Koh, I. H. J., Souza, R. B., Martins, A. M. 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S., Lozano, A., Lheureux, O., Badenes, R., Vincent, J. L., Creteur, J., Taccone, F. S., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Vincent, J. L., Creteur, J., Taccone, F. S., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Geeraerts, T., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Rubulotta, F., Waldauf, P., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kovari, F., Kongpolprom, N., Gulia, V., Lourenço, E., Melão, L., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Marreiros, A., Granja, C., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Gupta, D., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., Abu-Habsa, M., Ahmad, A., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Honeybul, S., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Pelosi, P., Calzia, E., Radermacher, P., Nußbaum, B., Hartmann, C., Huber-Lang, M., Gröger, M., Radermacher, P., Nußbaum, B., Nußbaum, B., Antonucci, E., Calzia, E., Pelosi, P., Radermacher, P., Hartmann, C., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Carteron, L., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Sbraga, F., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Berbel-Franco, D., Dastis, M., Moreno-Gonzalez, G., Perez-Sanchez, J., Romera-Peregrina, I., Abellan-Lencina, R., Martinez-Pascual, A., Fuentes-Mila, V., Gonzalez-Romero, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Ampatzidou, F., Sileli, M., Kehagioglou, G., Madesis, A., Karaiskos, T., Moursia, C., Maleoglou, H., Leleki, K., Drossos, G., Uz, Z., Ince, Y., Papatella, R., Bulent, E., Guerci, P., Ince, C., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Fleischmann, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Gattinoni, L., Reinhart, K., Hartog, C. S., Pérez, A. González, Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Albaiceta, G. Muñiz, Tamura, T., Yatabe, T., Miyajima, I., Yamashita, K., Yokoyama, M., Ampatzidou, F., Kehagioglou, G., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Drossos, G., Hathorn, K. E., Purtle, S. W., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., Rubulotta, F., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Cánovas, J., Sotos, F., López, A., Lorente, M., Burruezo, A., Torres, D., Polok, K., Włudarczyk, A., Górka, J., Hałek, A., Musiał, J., Szczeklik, W., Jazia, A. Ben, Jaziri, F., Bargouth, M., Bennasr, M., Turki, S., Abdelghani, K. Ben, Abdallah, T. Ben, de Grooth, H. J., Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Wykes, K., Jack, J., Morgan, P., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Espinoza, E. D. Valenzuela, Welsh, S. P., Motta, M. F., Guerra, E., Zerpa, M. C. l., Zechner, F., Furche, M., Berdaguer, F., Birri, P. N. Rubatto, Risso-Vazquez, A., Dubin, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Sánchez-Hurtado, L. A., Arvizu-Tachiquín, P. C., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Baltazar-Torres, J. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Poulose, V., Morales, M. A. Lopez, Castro, S., Pires, T., Melão, L., Krystopchuk, A., Pereira, I., Granja, C., Taniguchi, L. U., Pires, E. M. C., Vieira, Jr, J. M., Azevedo, L. C. P., Nurses of the Central and General ICUs of Shiraz Namazi Hospital, Sedation an Delirium Group Hospital Universitari de Bellvitge, SPACeR group (Surrey Peri-operative, Anaesthesia and Critical Care Collaborative Research Group), for the PRoVENT investigators and the PROVE Network, SEMICYUC/GETGAG Working Group, TAVeM study group, POPC-CB investigators, DESIRE (DExmedetomidine for Sepsis in ICU Randomized Evaluation) Trial Investigators, GEMINI, Bioethics work group of SEMICYUC, The FINNAKI Study Group, Queen Square Neuroanaesthesia and Neurocritical Care Resreach Group, Renal Transplantation HUVR, GEMINI, EDISVAL Group, EDISVAL Group, PLUG Working group, TAVeM study Group, The FINNAKI Study Group, on behalf of Department of Professional Development, ESICM, Critical Care Research Group, SIRAKI group, and Grupo ESBAGA
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- 2016
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23. Initiation of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock during out of hours versus working hours is not associated with increased mortality
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CCU Cardiologie, Team Medisch, Circulatory Health, Medische Staf Intensive Care, Regenerative Medicine and Stem Cells, CTC, Medische staf Anesthesiologie, Other research (not in main researchprogram), Infection & Immunity, van der Wal, P. S., Kraaijeveld, A. O., van der Heijden, J. J., van Laake, L. W., Platenkamp, M., de Heer, L. M., Braithwaite, S. A., van Eijk, M. M.J., Hermens, J. A.J., Cremer, O. L., Donker, D. W., Meuwese, C. L., CCU Cardiologie, Team Medisch, Circulatory Health, Medische Staf Intensive Care, Regenerative Medicine and Stem Cells, CTC, Medische staf Anesthesiologie, Other research (not in main researchprogram), Infection & Immunity, van der Wal, P. S., Kraaijeveld, A. O., van der Heijden, J. J., van Laake, L. W., Platenkamp, M., de Heer, L. M., Braithwaite, S. A., van Eijk, M. M.J., Hermens, J. A.J., Cremer, O. L., Donker, D. W., and Meuwese, C. L.
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- 2022
24. Changes in Magnetic Field Maps at QRS-Onset After Myocardial Infarction
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Hailer, B., Van Leeuwen, P., Donker, D., Rahn, N., Lange, S., Wehr, M., Aine, Cheryl J., editor, Stroink, Gerhard, editor, Wood, Charles C., editor, Okada, Yoshio, editor, and Swithenby, Stephen J., editor
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- 2000
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25. In silico testing of a non‑invasive, individualised PEEP titration method for optimal lung compliance during pressure support ventilation
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Warnaar, R., Oppersma, E., Cornet, A., Donker, D., Cardiovascular and Respiratory Physiology, and TechMed Centre
- Subjects
respiratory system ,circulatory and respiratory physiology ,respiratory tract diseases - Abstract
Introduction: Comprehensive quantification of respiratory system mechanics during pressure support ventilation (PSV) classically requires invasive measurements or interruptions of spontaneous breathing. This limits broad clinical applicability of these methods for lung compliance optimisation during PSV. Therefore, we present a non-invasive approach for individualised PEEP titration based on dynamic lung compliance measurements at the bedside. Objectives: This study focuses on the sensitivity of a non-invasive method for bedside quantification of dynamic lung compliance in response to simulated PEEP interventions in patients receiving PSV. Methods: An individual patient’s respiratory system was modelled in Simulink R2020b (The MathWorks, Inc., MA, USA) as an electrical ana-logue with a pressure dependent lung compliance (Fig. 1a). This in silico patient was ventilated in PSV mode applying 7 different PEEP levels: 0, 2, 4, 6, 8, 10, 12, and 14 cmH2O. Simulations were run during spontaneous breathing at each PEEP level. The expiratory time constant (RC-time = air-way resistance * respiratory system compliance = RAW * CRS) was esti-mated [1]. The airway resistance was determined as the time derivative of the airway pressure divided by the time derivative of the flow, both around zero flow at end-inspiration. CRS was calculated as the RC-time over the median airway resistance over all breaths. The correlation between true, i.e. modelled, and measured compliance was quantified with the Pearson correlation coefficient.Results. Both measured and modelled CRS at each PEEP level are shown in Fig. 1b. The measured compliances correlate well with the modelled compliances (r = 0.85, p < 0.01), although they show a systematic offset. Importantly, individualised titration of PEEP was possible using the pro-posed method, as the PEEP level for maximal lung compliance was iden-tical in both curves. Conclusion: We demonstrate that this method allows for non-invasive, individualised PEEP titration during PSV ventilation in a modelled clinical case. This approach has great potential for future bedside use, and there-fore deserves further clinical testing, aiming to optimise pressure sup-port ventilation, and promote patient-ventilator synchrony and weaning.
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- 2021
26. Distinct waveforms of peripheral arterial blood pressure tracings reveal preload‑, cardiac contractility‑ and afterload‑ defcient hemodynamic instability: an in‑silico simulation study
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Mulder, M., Broomé, M., Donker, D., Westerhof, B., Cardiovascular and Respiratory Physiology, and TechMed Centre
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- 2021
27. Preventing LVAD implantation by early short-term mechanical support and prolonged inodilator therapy: A case series with acute refractory cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation and optimised medical strategy
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Brugts, J. J., Manintveld, O., Constantinescu, A., Donker, D. W., van Thiel, R. J., Nieman, K., Jewbali, L. S. D., Zijlstra, F., and Caliskan, K.
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- 2014
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28. Transfusion of a disillusion?: When well-meant clinical intuition meets individualised physiology
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Donker, D. W., Cardiovascular and Respiratory Physiology, and TechMed Centre
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- 2021
29. Clinical Experience with Local Hyperthermia in Rotterdam
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Van der Zee, J., Van Rhoon, G. C., Broekmeyer-Reurink, M. P., Kuijs, A. E. M., Van Den Berg, A. P., Treurniet-Donker, D., Van Putten, W. L. J., Reinhold, H. S., Bicher, Haim I., editor, McLaren, John R., editor, and Pigliucci, Giuseppe M., editor
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- 1990
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30. Awake ECMO on the move to lung transplantation: serial monitoring of physical condition
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Hermens, J. A., Braithwaite, S. A., Platenkamp, M., Wijnandts, P. R., Van de Graaf, E. A., van der Kaaij, N. P., De Jong, M., Heijnen, G., Janssen, J., Kesecioglu, J., and Donker, D. W.
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- 2017
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31. An arterio-venous bridge for gradual weaning from adult veno-arterial extracorporeal life support
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Babar, Z UD, Sharma, A S, Ganushchak, Y M, Delnoij, T SR, Donker, D W, Maessen, J G, and Weerwind, P W
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- 2015
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32. Pharmacokinetics and Toxicity of Tacrolimus Early After Heart and Lung Transplantation
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Sikma, M. A., van Maarseveen, E. M., van de Graaf, E. A., Kirkels, J. H., Verhaar, M. C., Donker, D. W., Kesecioglu, J., and Meulenbelt, J.
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- 2015
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33. Mobile respiratory rescue support by offcentre initiation of extracorporeal membrane oxygenation
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Delnoij, T SR, Veldhuijzen, G, Strauch, U, Van Mook, W NKA, Bergmans, D CJJ, Bouman, E A, Lance, M D, Smets, M, Breedveld, P, Ganushchak, Y M, Weerwind, P, Kats, S, Roekaerts, P M, Maessen, J, and Donker, D W
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- 2015
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34. Towards a proactive therapy utilizing the modern spectrum of extracorporeal life support: a single-centre experience
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Sharma, A S, Weerwind, P W, Ganushchak, Y M, Donker, D W, and Maessen, J G
- Published
- 2015
- Full Text
- View/download PDF
35. Transfusion of a disillusion? When well-meant clinical intuition meets individualised physiology
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Medische Staf Intensive Care, Other research (not in main researchprogram), Donker, D. W., Medische Staf Intensive Care, Other research (not in main researchprogram), and Donker, D. W.
- Published
- 2021
36. Twelve years of circulatory extracorporeal life support at the University Medical Centre Utrecht
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Medische Staf Intensive Care, AIOS Anesthesiologie, Medische staf Anesthesiologie, Other research (not in main researchprogram), CTC, Circulatory Health, Team Medisch, Medische Staf Spoedeisende Hulp, Trialbureau Vitale Functies, Infection & Immunity, Brain, Meuwese, C L, Hermens, J A, de Haan, M, Braithwaite, S A, Ramjankhan, F, Buijsrogge, M P, de Jonge, N, Kirkels, J H, de Jong, M, Pasma, W, Vromen-Wijsman, J L P, Kraaijeveld, A O, de Waal, E E, Torn, E, Platenkamp, M, van der Heijden, J J, Cremer, O L, van Dijk, D, Donker, D W, Medische Staf Intensive Care, AIOS Anesthesiologie, Medische staf Anesthesiologie, Other research (not in main researchprogram), CTC, Circulatory Health, Team Medisch, Medische Staf Spoedeisende Hulp, Trialbureau Vitale Functies, Infection & Immunity, Brain, Meuwese, C L, Hermens, J A, de Haan, M, Braithwaite, S A, Ramjankhan, F, Buijsrogge, M P, de Jonge, N, Kirkels, J H, de Jong, M, Pasma, W, Vromen-Wijsman, J L P, Kraaijeveld, A O, de Waal, E E, Torn, E, Platenkamp, M, van der Heijden, J J, Cremer, O L, van Dijk, D, and Donker, D W
- Published
- 2021
37. Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design
- Author
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Goligher, E. C., Combes, A., Brodie, D., Ferguson, N. D., Pesenti, A. M., Ranieri, V. M., Slutsky, A. S., Beale, R., Brochard, L., Chiche, J. -D., Fan, E., de Backer, D., Francois, G., Laffey, J., Mercat, A., Mcauley, D. F., Muller, T., Quintel, M., Vincent, J. -L., Taccone, F. S., Peperstraete, H., Morimont, P., Schmidt, M., Levy, B., Diehl, J. -L., Guervilly, C., Capelier, G., Vieillard-Baron, A., Messika, J., Karagiannidis, C., Moerer, O., Urbino, R., Antonelli, M., Mojoli, F., Alessandri, F., Grasselli, G., Donker, D., Ferrer, R., Mancebo, J., Fanelli, V., Pham, T., Goligher E.C., Combes A., Brodie D., Ferguson N.D., Pesenti A.M., Ranieri V.M., Slutsky A.S., Beale R., Brochard L., Chiche J.-D., Fan E., de Backer D., Francois G., Laffey J., Mercat A., McAuley D.F., Muller T., Quintel M., Vincent J.-L., Taccone F.S., Peperstraete H., Morimont P., Schmidt M., Levy B., Diehl J.-L., Guervilly C., Capelier G., Vieillard-Baron A., Messika J., Karagiannidis C., Moerer O., Urbino R., Antonelli M., Mojoli F., Alessandri F., Grasselli G., Donker D., Ferrer R., Mancebo J., Fanelli V., and Pham T.
- Subjects
Artificial ventilation ,Adult ,Male ,medicine.medical_specialty ,Extracorporeal Circulation ,Organ Dysfunction Scores ,medicine.medical_treatment ,Acute respiratory distress syndrome ,Extracorporeal carbon dioxide removal ,Predictive enrichment ,Ventilator-induced lung injury ,Pilot Projects ,Aged ,Blood Gas Analysis ,Carbon Dioxide ,Extracorporeal Membrane Oxygenation ,Female ,Humans ,Linear Models ,Middle Aged ,ROC Curve ,Simplified Acute Physiology Score ,Treatment Outcome ,Critical Care and Intensive Care Medicine ,Hypoxemia ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Linear regression ,Extracorporeal membrane oxygenation ,medicine ,Journal Article ,Respiratory system ,Tidal volume ,business.industry ,Extracorporeal circulation ,030208 emergency & critical care medicine ,respiratory system ,030228 respiratory system ,Sample size determination ,Cardiology ,medicine.symptom ,business - Abstract
Purpose To describe the variability and determinants of the effect of extracorporeal CO2 removal (ECCO2R) on tidal volume (V-t), driving pressure (Delta P), and mechanical power (Power(RS)) and to determine whether highly responsive patients can be identified for the purpose of predictive enrichment in ECCO2R trial design. Methods Using data from the SUPERNOVA trial (95 patients with early moderate acute respiratory distress syndrome), the independent effects of alveolar dead space fraction (ADF), respiratory system compliance (Crs), hypoxemia (PaO2/FiO(2)), and device performance (higher vs lower CO2 extraction) on the magnitude of reduction in V-t, Delta P, and Power(RS) permitted by ECCO2R were assessed by linear regression. Predicted and observed changes in Delta P were compared by Bland-Altman analysis. Hypothetical trials of ECCO2R, incorporating predictive enrichment and different target CO2 removal rates, were simulated in the SUPERNOVA study population. Results Changes in V-t permitted by ECCO2R were independently associated with ADF and device performance but not PaO2/FiO(2). Changes in Delta P and Power(RS) were independently associated with ADF, Crs, and device performance but not PaO2/FiO(2). The change in Delta P predicted from ADF and Crs was moderately correlated with observed change in Delta P (R-2 0.32, p < 0.001); limits of agreement between observed and predicted changes in Delta P were +/- 3.9 cmH(2)O. In simulated trials, restricting enrollment to patients with a larger predicted decrease in Delta P enhanced the average reduction in Delta P, increased predicted mortality benefit, and reduced sample size and screening size requirements. The increase in statistical power obtained by restricting enrollment based on predicted Delta P response varied according to device performance as specified by the target CO2 removal rate. Conclusions The lung-protective benefits of ECCO2R increase with higher alveolar dead space fraction, lower respiratory system compliance, and higher device performance. ADF and Crs, rather than severity of hypoxemia, should be the primary factors determining whether to enroll patients in clinical trials of ECCO2R.
- Published
- 2019
38. Neurological Complications in Patients Requiring Durable VAD Systems after ECLS Support. On Behalf of ECLS- Durable MCS Study Group
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Saeed, D., primary, Potapov, E., additional, Loforte, A., additional, Morshuis, M., additional, Schibilsky, D., additional, Zimpfer, D., additional, Riebandt, J., additional, Pappalardo, F., additional, Attisani, M., additional, Rinaldi, M., additional, Haneya, A., additional, Ramjankhan, F., additional, Donker, D., additional, Jorde, U., additional, Stein, J., additional, Tsyganenko, D., additional, Jawad, K., additional, Wieloch, R., additional, Ayala, R., additional, Cremer, J., additional, Borger, M., additional, Lichtenberg, A., additional, and Gummert, J., additional
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- 2021
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39. Venoarterial extracorporeal membrane oxygenation in elective high-risk percutaneous coronary intervention : a viable option?
- Author
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Meuwese, C L, Ramjankhan, F Z, Kraaijeveld, A O, Donker, D W, Meuwese, C L, Ramjankhan, F Z, Kraaijeveld, A O, and Donker, D W
- Published
- 2020
40. Venoarterial extracorporeal membrane oxygenation in elective high-risk percutaneous coronary intervention: a viable option?
- Author
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Medische Staf Intensive Care, CTC, Circulatory Health, Team Medisch, Other research (not in main researchprogram), Meuwese, C L, Ramjankhan, F Z, Kraaijeveld, A O, Donker, D W, Medische Staf Intensive Care, CTC, Circulatory Health, Team Medisch, Other research (not in main researchprogram), Meuwese, C L, Ramjankhan, F Z, Kraaijeveld, A O, and Donker, D W
- Published
- 2020
41. Powerful spin-offs … fostering flexibility, creativity and individualised critical care!
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Medische Staf Intensive Care, Other research (not in main researchprogram), Donker, D. W., Medische Staf Intensive Care, Other research (not in main researchprogram), and Donker, D. W.
- Published
- 2020
42. End–diastolic myofiber stress and ejection strain increase with ventricular volume overload: Serial in–vivo analyses in dogs with complete atrioventricular block
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Donker, D. W., Volders, P. G. A., Arts, T., Bekkers, B. C. A. M., Hofstra, L., Spätjens, R. L. H. M. G., Beekman, J. D. M., Borgers, M., Crijns, H. J. G. M., and Vos, M. A.
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- 2005
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43. Re: Lindstrom et al. Veno-right ventricular cannulation reduces recirculation in extracorporeal membrane oxygenation
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Simons, A P, Donker, D W, and Weerwind, P W
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- 2013
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44. Initiation of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock during out of hours versus working hours is not associated with increased mortality.
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van der Wal, PS, Kraaijeveld, AO, van der Heijden, JJ, van Laake, LW, Platenkamp, M, de Heer, LM, Braithwaite, SA, van Eijk, MMJ, Hermens, JAJ, Cremer, OL, Donker, DW, Meuwese, CL, van der Wal, P S, Kraaijeveld, A O, van der Heijden, J J, van Laake, L W, de Heer, L M, Braithwaite, S A, Cremer, O L, and Donker, D W
- Published
- 2022
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45. Mobile extracorporeal membrane oxygenation after traumatic freshwater submersion using bi-caval dual lumen catheter
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Geelen, C. C., Bouman, E. A., Roekaerts, P. M., Breedveld, P., Strauch, U., Van Garsse, L., Weerwind, P. W., and Donker, D. W.
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- 2011
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46. Transition from VA-ECMO to Durable VAD Systems. Do We Need Cardiopulmonary Bypass Machine? On Behalf of ECMO-VAD Study Group
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Saeed, D., primary, Potapov, E.V., additional, Loforte, A., additional, Morshuis, M., additional, Schibilsky, D., additional, Zimpfer, D., additional, Riebandt, J., additional, Pappalardo, F., additional, Attisani, M., additional, Haneya, A., additional, Ramjankhan, F., additional, Donker, D., additional, Tsyganenko, D., additional, Jorde, U., additional, Jawad, K., additional, Wieloch, R., additional, Ayala, R., additional, Cremer, J., additional, Borger, M., additional, Lichtenberg, A., additional, and Gummert, J.F., additional
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- 2020
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47. Implanting Durable VAD Systems in Patients on VA-ECMO: Comparing Less Invasive to Sternotomy Approach. On Behalf of ECMO-VAD Study Group
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Saeed, D., primary, Potapov, E.V., additional, Loforte, A., additional, Morshuis, M., additional, Schibilsky, D., additional, Zimpfer, D., additional, Riebandt, J., additional, Pappalardo, F., additional, Attisani, M., additional, Haneya, A., additional, Ramjankhan, F., additional, Donker, D., additional, Tsyganenko, D., additional, Jorde, U., additional, Jawad, K., additional, Wieloch, R., additional, Ayala, R., additional, Aspern, C., additional, Cremer, J., additional, Borger, M., additional, Lichtenberg, A., additional, and Gummert, J.F., additional
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- 2020
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48. Light and noise nuisance … deciphered yet underappreciated ‘rosetta stone’ of the modern ICU?
- Author
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Donker, D. W.
- Subjects
Critical Care and Intensive Care Medicine - Abstract
In everyday life, we take for granted that public authorities protect us from an unhealthy environment, including light and noise pollution. In recent years, about 1200 kilometres of noise barriers have been built alongside Dutch highways with costs approaching a billion euros.[1] Also, more than 50 cities in the Netherlands have successfully taken initiatives to reduce the artificial light pollution in the past six years, as our country is well known to rank among the literally most illuminated ones in the world.[2] These investments seem to be reasonable as adverse health effects from environmental light and noise pollution have long and widely been recognised.[3,4] How these potentially detrimental effects of artificial light and distressing noise acting on the human body translate into the best possible care that we strive to provide within our modern ICU environment is an area of increasing professional awareness, interest and research. Yet, we all realise that not only light and noise, but numerous physical and psychological stressors may negatively affect individual ICU patients. Also, the impact of these factors may vary considerably among individuals, which makes it even more difficult for caregivers to prioritise among apparently competing aspects of care in their daily practice.[5] A comprehensive, narrative review by Koen Simons and colleagues in this issue of the Netherlands Journal of Critical Care provides us with up-to-date information on the ‘impact of intensive care unit light and noise exposure on critically ill patients’.[6] Here, we gain more insights and learn how a multimodal approach to our ICU environment may aid to optimise light exposure and reduce noise. This may not only improve our patients’ sleep and general wellbeing, but also reduce the incidence of delirium. The latter seems especially relevant since the pharmacological prevention of delirium has repeatedly been shown to be disappointing, as recently confirmed again in a large Dutch trial.[7] All this evidence sets the stage to further promote nonpharmacological interventions in the ICU to prevent delirium.[8] Therefore, we should do our best to limit controllable stressors in the ICU in order to improve patient comfort and hopefully enhance the individual prognosis.[6] As our traditional focus on the medical and technical aspects of critical care has led us to asymptotically reach current therapeutic optima; human factors and soft skills are no longer far in the horizon of the modern ICU.
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- 2019
49. Feasibility and safety of extracorporeal CO 2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study
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Combes, A, Fanelli, V, Pham, T, Ranieri, Vm, Goligher, Ec, Brodie, D, Pesenti, A, Beale, R, Brochard, L, Chiche, Jd, Fan, E, de Backer, D, Francois, G, Ferguson, N, Laffey, J, Mercat, A, Mcauley, Df, Muller, T, Quintel, M, Vincent, Jl, Taccone, Fs, Peperstraete, H, Morimont, P, Schmidt, M, Levy, B, Diehl, Jl, Guervilly, C, Capelier, G, Vieillard-Baron, A, Messika, J, Karagiannidis, C, Moerer, O, Urbino, R, Antonelli, Massimo, Mojoli, F, Alessandri, F, Grasselli, G, Donker, D, Ferrer, R, Mancebo, J, Slutsky, As, Combes, Alain, Fanelli, Vito, Pham, Tai, and Ranieri, V Marco
- Subjects
Male ,Adult ,Canada ,ARDS ,medicine.medical_treatment ,Critical Care and Intensive Care Medicine ,Extracorporeal ,03 medical and health sciences ,Extracorporeal Membrane Oxygenation ,0302 clinical medicine ,Mechanical ventilation ,Settore MED/41 - ANESTESIOLOGIA ,Extracorporeal carbon dioxide removal ,Journal Article ,Extracorporeal membrane oxygenation ,medicine ,Humans ,Prospective Studies ,Adverse effect ,Acute respiratory distress syndrome ,Ventilator-induced lung injury ,Acidosis, Respiratory ,Aged ,Analysis of Variance ,Carbon Dioxide ,Europe ,Feasibility Studies ,Female ,Middle Aged ,Respiration, Artificial ,Respiratory Distress Syndrome, Adult ,Respiratory Distress Syndrome ,business.industry ,Respiration ,030208 emergency & critical care medicine ,medicine.disease ,Confidence interval ,030228 respiratory system ,Pneumothorax ,Anesthesia ,Artificial ,Respiratory ,Breathing ,Acidosis ,business - Abstract
Purpose: We assessed feasibility and safety of extracorporeal carbon dioxide removal (ECCO 2 R) to facilitate ultra-protective ventilation (V T 4 mL/kg and P PLAT ≤ 25 cmH 2 O) in patients with moderate acute respiratory distress syndrome (ARDS). Methods: Prospective multicenter international phase 2 study. Primary endpoint was the proportion of patients achieving ultra-protective ventilation with PaCO 2 not increasing more than 20% from baseline, and arterial pH > 7.30. Severe adverse events (SAE) and ECCO 2 R-related adverse events (ECCO 2 R-AE) were reported to an independent data and safety monitoring board. We used lower CO 2 extraction and higher CO 2 extraction devices (membrane lung cross-sectional area 0.59 vs. 1.30 m 2 ; flow 300–500 mL/min vs. 800–1000 mL/min, respectively). Results: Ninety-five patients were enrolled. The proportion of patients who achieved ultra-protective settings by 8 h and 24 h was 78% (74 out of 95 patients; 95% confidence interval 68–89%) and 82% (78 out of 95 patients; 95% confidence interval 76–88%), respectively. ECCO 2 R was maintained for 5 [3–8] days. Six SAEs were reported; two of them were attributed to ECCO 2 R (brain hemorrhage and pneumothorax). ECCO 2 R-AEs were reported in 39% of the patients. A total of 69 patients (73%) were alive at day 28. Fifty-nine patients (62%) were alive at hospital discharge. Conclusions: Use of ECCO 2 R to facilitate ultra-protective ventilation was feasible. A randomized clinical trial is required to assess the overall benefits and harms. Clinicaltrials.gov: NCT02282657.
- Published
- 2019
50. Light and noise nuisance … deciphered yet underappreciated ‘rosetta stone’ of the modern ICU?
- Author
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Medische Staf Intensive Care, Other research (not in main researchprogram), Donker, D. W., Medische Staf Intensive Care, Other research (not in main researchprogram), and Donker, D. W.
- Published
- 2019
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