10 results on '"Dong Cho Lee"'
Search Results
2. Effect of Solcoseryl in Corneal Alkali Burn Rat Model
- Author
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Hoon Kim, Kyong Jin Cho, Hong-Bee Kim, Jae-Hwi Seo, and Dong Cho Lee
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business.industry ,Rat model ,Medicine ,Alkali burn ,business ,Nuclear chemistry - Published
- 2021
3. Fabrication and Evaluation of the Flexible and Implantable Soft Micro Electrode for Retinal Prosthesis
- Author
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Dong Cho Lee, Seung-Ha Lee, Ju-Yeoul Baek, Gu-Han Kwon, Moo-Hwan Chang, Kyung-Sun, and Sang Hoon Lee
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Materials science ,Polydimethylsiloxane ,Biocompatibility ,technology, industry, and agriculture ,Isotropic etching ,law.invention ,chemistry.chemical_compound ,Microelectrode ,chemistry ,Etching (microfabrication) ,law ,Electrode ,Photolithography ,Electroplating ,Biomedical engineering - Abstract
This paper presents a polydimethylsiloxane(PDMS)-based flexible and implantable micro electrode for the retinal prosthesis. The patterning of the electrode and the wires was performed through the photolithography and chemical etching process after e-beam deposition Ti and Au, and the thick electrode was fabricated through the electroplating process. We carried out in-vivo test for the evaluation of biocompatibility by implanting electrodes under the ICR mouse skin for 45 days. The electrode was implantetd under the retina of rabbit's eye to investigate the feasibility as a retinal prosthesis.
- Published
- 2006
4. The Results of Nation-Wide Registry of Age-related Macular Degeneration in Korea
- Author
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Won Ki Lee, Kuhl Huh, Se Woong Kang, Hyoung Jun Koh, Gwang Yul Chang, Gwang Su Kim, Young Hee Yoon, Yun Young Kim, Tae Gon Lee, Jun Hyun Kim, Tae Kwan Park, Young Duk Kim, Si Yeol Kim, Sang Woong Moon, Sun Ryang Bae, Woo Hoo Nam, Nam Chun Joe, Jung Hee Lee, Young Joon Joe, Kyu Hyung Park, Sang Kook Kim, Jong In Kim, Ha Kyoung Kim, Gwang Ju Choi, Jae Kyoun Ahn, Jae Hoon Kang, Woo Hyok Chang, Dong Cho Lee, Yeon Sung Moon, Young Hun Ohn, Hee Yoon Joe, Hum Chung, Sung Chul Lee, Boo Sup Oum, In Young Kim, Mu Hwan Chang, Sang Jun Lee, Young Wok Joe, Byung Ro Lee, Hee Sung Yoon, Dong Heun Nam, Soon Hyun Kim, Chang Ryong Kim, Ill Han Yoon, Sung Jin Lee, Shin Dong Kim, Sukjun Lee, Su Jeong Song, Su Young Lee, Sung Won Joe, Pill Young Lee, Sung Pyo Park, Hyeoung Chan Kim, Ju Eun Lee, Hyeong Gon Yu, Jae Ryung Oh, Soon Ill Kwon, Oh Woong Kwon, Yeon Sik Yang, Chul Gu Kim, Hyoung Su Kim, and Si Dong Kim
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medicine.medical_specialty ,Past medical history ,genetic structures ,medicine.diagnostic_test ,business.industry ,Incidence (epidemiology) ,Fundus photography ,Retinal ,Macular degeneration ,medicine.disease ,Occult ,eye diseases ,Ophthalmology ,chemistry.chemical_compound ,chemistry ,Diabetes mellitus ,Angiography ,medicine ,sense organs ,business - Abstract
Purpose: To evaluate the incidence and clinical features of age-related macular degeneration (AMD) in Korea Methods: Web-based (www.armd-nova.or.kr) registration was conducted for AMD patients aged 50 or more who were newly diagnosed by retinal specialists in Korea from August 20, 2005 to August 20, 2006. Patient data including ophthalmologic examination, fundus photography, fluorescein angiogram and/or indocyanin green angiogram (ICG), past medical history, behavioral habit, combined systemic diseases were up-loaded. Results: Among finally enrolled 1,141 newly diagnosed AMD patients, 690 patients (60.5%) were male and 451 patients (39.5%) were female. The average age of AMD patients was 69.78.0. Early AMD was observed in 190 patients and 951 patients had late AMD. Classic choroidal neovascular membrane (CNVM) was observed in 18.6% of exudative AMD patients and 63.4 % had occult CNVM. Subfoveal CNVM was observed in 80.4% of the patients with CNVM. Among the 580 exudative AMD eyes that performed indocyanin green angiography (ICG), 184 eyes (31.7%) had polypoidal choroidal vasculopathy (PCV) and 36 eyes (6.2%) showed retinal angiomatous proliferation (RAP). Age, male gender, smoking, diabetes and hypertension significantly increased the risk of the AMD among Koreans. Conclusions: Because of the low rate of participation by retinal specialists, definite incidence of AMD was not obtainable. However, the estimated 1-year AMD incidence in the Pusan area of Korea is at least 0.4%. In contrast to Western people, 31.7% of exudative AMD cases were revealed to be PCV and 6.2% were revealed to be RAP. This discrepancy between ethnic groups should be considered in the diagnosis and treatment modality selection of Korean AMD patients.
- Published
- 2010
5. Genotype, Coagulase Type and Antimicrobial Susceptibility of Methicillin-Resistant Staphylococcus aureus Isolated from Dermatology Patients and Healthy Individuals in Korea
- Author
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Sung-Ho Hur, Mi-Rae Choi, Dong-Yeul Kwon, Jin-Kyung Kim, Se-Young Park, Pil-Seung Kwon, Soo-Myung Hwang, Yunsop Chong, Na-Young Shin, Eun-Sook Shim, Dong-Cho Lee, Ho-Jun Kim, Hyo-Bin Lim, Shin-Moo Kim, Seok-Don Park, and Bo-Suk Kim
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medicine.medical_specialty ,business.industry ,Fusidic acid ,Immunology ,Erythromycin ,Clindamycin ,Mupirocin ,biochemical phenomena, metabolism, and nutrition ,bacterial infections and mycoses ,medicine.disease_cause ,Microbiology ,Dermatology ,Methicillin-resistant Staphylococcus aureus ,chemistry.chemical_compound ,chemistry ,Amikacin ,Virology ,medicine ,Vancomycin ,Coagulase ,business ,medicine.drug - Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent dermatology pathogens in hospitals and increasingly recognized in communities. We determined PFGE pattern of SmaI-restricted genomic DNA, coagulase type, and antimicrobial susceptibility of MRSA isolated in 2008 from dermatology inpatients and healthy hospital employees in A Hospital and from primary school children in Iksan city, Korea. Overall, the isolation rate of MRSA was 3.8% from the 788 normal persons: 4.9% from hospital employees and 1.1% from primary school children. MRSA was isolated in six of 13 (46.2%) family members of four school children with MRSA. The most prevalent coagulase serotype was Ⅱ from patients and V from healthy individuals. Ten of twenty and six of twenty MRSA isolates from patients and from healthy personnel, respectively, had identical PFGE patterns, suggesting that these are originated from identical clones. Against MRSA from patients, only vancomycin was the most active (MIC range ≤2 μg/㎖), whereas the resistance rates were 35% to rifampin and 65% to mupirocin. The resistance rates of patient isolates were ≥90% to amikacin, clindamycin, ciprofloxacin, erythromycin, fusidic acid, gentamicin and tetracycline. In conclusion, the MRSA carriage rates of healthy hospital workers were relatively high, 2.3~7.7%, depending on groups. Family members of a few primary school children with MRSA showed a high carriage rate, suggesting that intrafamily transmission occurred. MRSAs isolated from dermatology inpatients were relatively more resistant to various antimicrobial agents, including mupirocin, but all isolates were susceptibility to vancomycin.
- Published
- 2009
6. A Solitary Fibrofolliculoma in the Eyelid
- Author
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Dong Cho Lee, Moo-Hwan Chang, and June-Kyu Chang
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Adult ,Fibrofolliculoma ,Case Report ,Fibroma ,Ophthalmologic Surgical Procedures ,Eyelid Neoplasms ,Diagnosis, Differential ,medicine ,Humans ,business.industry ,General Medicine ,Anatomy ,Eyelid Neoplasm ,medicine.disease ,eye diseases ,body regions ,medicine.anatomical_structure ,Chalazion ,Female ,sense organs ,Eyelid ,Eyelid neoplasm ,business ,Solitary fibrofolliculoma - Abstract
Purpose To report the first case of a solitary eyelid fibrofolliculoma and to review the literature. Methods A 37-year-old female patient visited the outpatient department with a lesion in the right upper lid that had been growing steadily for a year. The patient had visited the local clinic, and under the diagnosis of chalazion had received incision and curettage twice, but the lesion had recurred. Results The 5×5 mm lesion was located near the upper lid margin. It was a red, hemispheric, smooth nodule, relatively solid to palpation and not painful. Excision and biopsy were performed, and through a histological exam, the diagnosis of fibrofolliculoma was later confirmed. Conclusions Solitary fibrofolliculoma is rare, and to the authors' knowledge, a lesion arising in the eyelid has not yet been reported. Fibrofolliculoma should be included in the differential diagnosis when a localized mass lesion arising in the eyelid is encountered.
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- 2007
7. A Case of Optic Neuropathy Associated with MELAS Syndrome
- Author
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Jung Hyun Ahn, Sung Eun Kyung, Myung Won Lee, and Dong Cho Lee
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Pathology ,medicine.medical_specialty ,genetic structures ,Cerebral infarction ,business.industry ,medicine.disease ,MELAS syndrome ,eye diseases ,Visual field ,Optic neuropathy ,Ophthalmology ,Epilepsy ,Lactic acidosis ,medicine ,Optic nerve ,business ,Hemianopsia - Abstract
Purpose: The purpose of this case report is to describe accompanying ocular findings, especially optic neuropathy, in a patient with MELAS syndrome. Methods: A 10-year-old male patient who had lactic acidosis and neurological symptoms (loss of consciousness, vomiting, epilepsy, decreased vision, and constricted visual field), underwent a brain magnetic resonance imaging (MRI) scan and a molecular genetic analysis. Results: A diagnosis of cerebral infarction due to occlusion in the right posterior cerebral artery was made and confirmed by MRI scan. The diagnosis of MELAS syndrome was confirmed by performing molecular genetic analysis demonstrating the transformation of the mitochondrial tRNAleu(UUR) gene (MTTL1) A to G(3243). According to the ocular examinations, the patientꡑs left eye showed decreased vision, hemianopsia, relative afferent pupillary defects, mild swelling of optic nerve, and decreased amplitude on visual evoked potential exam. Conclusions: We encountered a case of MELAS syndrome involving optic neuropathy, which can (although rarely) occur with this syndrome. Therefore, in patients with an optic neuropathy of uncertain etiology, clinicians should consider performing comprehensive ocular exams and molecular genetic exams to rule out the possibility of genetic diseases.
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- 2007
8. Wernicke-Korsakoff Syndrome Associated with Hyperemesis Gravidarum
- Author
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Moo Hwan Chang, Dong Cho Lee, and Chang Kyoon Yoon
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Adult ,Ataxia ,Eye Diseases ,genetic structures ,Vision Disorders ,Neurological examination ,Hyperemesis gravidarum ,Pregnancy ,Hyperemesis Gravidarum ,medicine ,Humans ,Diplopia ,Wernicke–Korsakoff syndrome ,medicine.diagnostic_test ,business.industry ,General Medicine ,medicine.disease ,eye diseases ,Pregnancy Complications ,Korsakoff Syndrome ,Anesthesia ,Decreased Visual Acuity ,Vomiting ,Female ,Upbeat nystagmus ,medicine.symptom ,business - Abstract
Purpose The authors hereby describe a case of Wernicke-Korsakoff syndrome with accompanying ocular findings that is caused by hyperernesis gravidarum. Methods We experienced a 27-year-old female at 12 weeks of pregnancy, who visited our clinic because of weight loss, gait disturbance, decreased mentality and dizziness after prolonged vomiting for 2 months. Neurological examination demonstrated ataxia of gait and loss of orientation. Ophthalmologic examination showed decreased visual acuity, upbeat nystagmus, diplopia and retinal hemorrhage. Results We report a relatively rare case of Wernicke-Korsakoff syndrome with ophthalmic symptoms induced by hyperemesis gravidarum. Conclusions If a pregnant women has symptoms of severe vomiting along with other ocular findings such as retinal hemorrhage or restricted extraocular movement, one must suspect the diagnosis of Wernicke-Korsakoff syndrome, and should start appropriate treatment immediately.
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- 2005
9. The Effect of Low-Dose Doxycycline Therapy in Chronic Meibomian Gland Dysfunction
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Seo Eun Yoo, Moo Hwan Chang, and Dong Cho Lee
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Male ,medicine.medical_specialty ,Administration, Oral ,Placebo ,Gastroenterology ,law.invention ,Randomized controlled trial ,Refractory ,law ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Doxycycline ,Dose-Response Relationship, Drug ,business.industry ,Low dose ,Meibomian gland dysfunction ,Meibomian Glands ,General Medicine ,Middle Aged ,Anti-Bacterial Agents ,Surgery ,Dose–response relationship ,Treatment Outcome ,Tears ,Chronic Disease ,Eyelid Diseases ,Female ,business ,Follow-Up Studies ,medicine.drug - Abstract
Purpose The aim was to investigate the effect of low dose doxycycline (20 mg) therapy in patients with chronic meibomian gland dysfunction that were refractory to conventional therapy. Methods The randomized prospective study enrolled 150 patients (300 eyes) who have chronic meibomian gland dysfunction and who didn't respond to lid hygiene and topical therapy for more than 2 months. All topical therapy was stopped for at least 2 weeks prior to beginning the study. After conducting the tear break up time test (TBUT) and Schirmer test, the authors randomly divided the patients into three groups a high dose group (doxycycline, 200 mg, twice a day), a low dose group (doxycycline, 20 mg, twice a day) and a control group (placebo). After one month, the author repeated the TBUT and Schirmer tests, and analyzed the degree of symptomatic improvement. Results Compared to the control group, both the high and low dose group showed statistically significant differences after treatment in TBUT, Schirmer test, the number of symptoms reported and the degree of improvement of subjective symptoms. However, there was no statistically significant difference between the high and low dose group after treatment in TBUT (9.42 +/- 2.87 sec, 9.54 +/- 1.58 sec, p=0.726), Schirmer test (19.98 +/- 4.05 mm, 19.65 +/- 5.02 mm, p=0.624), the number of symptoms reported (1.45 +/- 0.62, 1.53 +/- 0.52, p=0.304), as well as the degree of improvement of subjective symptoms (p=0.288). The high dose group (18 patients, 39.13%) reported side effects more frequently than did the low dose group (8 patients, 17.39%) (P=0.002). Conclusions Low dose doxycycline (20 mg twice a day) therapy was effective in patients with chronic meibomian gland dysfunction that were refractory to conventional therapy.
- Published
- 2005
10. Fabrication and Evaluation of the Flexible and Implantable Soft Micro Electrode for Retinal Prosthesis.
- Author
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Gu-Han Kwon, Ju-Yeoul Baek, Seung-Ha Lee, Moo-Hwan Chang, Dong-Cho Lee, Kyung-Sun, and Sang-Hoon Lee
- Published
- 2006
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