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24 results on '"Donaldson, Mandy"'

12. Combination of Peptide YY3–36with GLP-17–36 amideCauses an Increase in First-Phase Insulin Secretion after IV Glucose

Author

Tan, Tricia M., primary, Salem, Victoria, additional, Troke, Rachel C., additional, Alsafi, Ali, additional, Field, Benjamin C. T., additional, De Silva, Akila, additional, Misra, Shivani, additional, Baynes, Kevin C. R., additional, Donaldson, Mandy, additional, Minnion, James, additional, Ghatei, Mohammad A., additional, Godsland, Ian F., additional, and Bloom, Stephen R., additional

Published
2014
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18. Subcutaneous Injection of Kisspeptin-54 Acutely Stimulates Gonadotropin Secretion in Women With Hypothalamic Amenorrhea, But Chronic Administration Causes Tachyphylaxis

Author

Jayasena, Channa N., primary, Nijher, Gurjinder M. K., additional, Chaudhri, Owais B., additional, Murphy, Kevin G., additional, Ranger, Amita, additional, Lim, Adrian, additional, Patel, Daksha, additional, Mehta, Amrish, additional, Todd, Catriona, additional, Ramachandran, Radha, additional, Salem, Victoria, additional, Stamp, Gordon W., additional, Donaldson, Mandy, additional, Ghatei, Mohammad A., additional, Bloom, Stephen R., additional, and Dhillo, Waljit S., additional

Published
2010
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20. Subcutaneous Injection of Kisspeptin-54 Acutely Stimulates Gonadotropin Secretion in Women with Hypothalamic Amenorrhea, But Chronic Administration Causes Tachyphylaxis

Author

Jayasena, Channa N., primary, Nijher, Gurjinder K., primary, Chaudhri, Owais B., primary, Murphy, Kevin G., primary, Ranger, Amita, primary, Lim, Adrian, primary, Patel, Daksha, primary, Mehta, Amrish, primary, Todd, Catriona, primary, Ramachandran, Radha, primary, Salem, Victoria, primary, Stamp, Gordon W., primary, Donaldson, Mandy, primary, Ghatei, Mohammad A., primary, Bloom, Stephen R., primary, and Dhillo, Waljit S., primary

Published
2009
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22. Dynamic assays of inhibin B and oestradiol following buserelin acetate administration as predictors of ovarian response in IVF.

Author

Ravhon, Amir, Lavery, Stuart, Michael, Sappho, Donaldson, Mandy, Margara, Raul, Trew, Geoff, Winston, Robert, Ravhon, A, Lavery, S, Michael, S, Donaldson, M, Margara, R, Trew, G, and Winston, R

Subjects
INFERTILITY treatment, LUTEINIZING hormone releasing hormone, FERTILITY drugs, DOSE-effect relationship in pharmacology, ESTRADIOL, FERTILIZATION in vitro, FOLLICLE-stimulating hormone, FORECASTING, INFERTILITY, OVARIES, OVUM, PEPTIDES, PROTEINS, CYTOMETRY, RECOMBINANT proteins, TREATMENT effectiveness, THERAPEUTICS
Abstract

The study was designed to examine whether dynamic measurements of inhibin B and oestradiol following single administration of buserelin acetate were correlated with the ovarian response to stimulation in IVF. A total of 37 patients undergoing IVF treatment was studied when the long protocol was started in the early follicular phase. Blood samples were taken twice: on day 2 of the menstrual cycle, before the first s.c. administration of buserelin acetate 0.5 mg and on day 3, 24 h later. Inhibin B and oestradiol concentrations were compared with the ovarian response to stimulation. The ovarian response was defined in two ways: 'number of oocytes/total recombinant (r) follicle stimulating hormone (FSH) dose'; and 'square-root (number of follicles/total rFSH dose)'. The following measurements were highly correlated with the ovarian response to stimulation: increase in oestradiol (day 3-day 2 oestradiol concentration) [correlation coefficient (r) = 0.68, P: < 0.0001] and sum of inhibin B (day 2 + day 3 inhibin B concentrations) (r = 0.6, P: < 0.0001). Age and basal concentrations of FSH and inhibin B were inferior to the above measurements in terms of correlation with the ovarian response. In conclusion, dynamic measurements of inhibin B and oestradiol following single administration of buserelin acetate were highly correlated with the ovarian response to stimulation for IVF treatment. [ABSTRACT FROM AUTHOR]

Published
2000
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23. Endocrinology. Dynamic assays of inhibin B and oestradiol following buserelin acetate administration as predictors of ovarian response in IVF

Author

Ravhon, Amir, Lavery, Stuart, Michael, Sappho, Donaldson, Mandy, Margara, Raul, Trew, Geoff, and Winston, Robert

Abstract

The study was designed to examine whether dynamic measurements of inhibin B and oestradiol following single administration of buserelin acetate were correlated with the ovarian response to stimulation in IVF. A total of 37 patients undergoing IVF treatment was studied when the long protocol was started in the early follicular phase. Blood samples were taken twice: on day 2 of the menstrual cycle, before the first s.c. administration of buserelin acetate 0.5 mg and on day 3, 24 h later. Inhibin B and oestradiol concentrations were compared with the ovarian response to stimulation. The ovarian response was defined in two ways: `number of oocytes/total recombinant (r) follicle stimulating hormone (FSH) dose'; and `square-root (number of follicles/total rFSH dose)'. The following measurements were highly correlated with the ovarian response to stimulation: increase in oestradiol (day 3–day 2 oestradiol concentration) [correlation coefficient (r) = 0.68, P < 0.0001] and sum of inhibin B (day 2 + day 3 inhibin B concentrations) (r = 0.6, P < 0.0001). Age and basal concentrations of FSH and inhibin B were inferior to the above measurements in terms of correlation with the ovarian response. In conclusion, dynamic measurements of inhibin B and oestradiol following single administration of buserelin acetate were highly correlated with the ovarian response to stimulation for IVF treatment.

Published
2000

24. Lesson of the week: interfering antibodies affecting immunoassays in woman with pet rabbits.

Author

Park A, Edwards M, Donaldson M, Ghatei M, and Meeran K

Subjects
Animals, Antibodies, Heterophile immunology, Colonic Diseases, Functional immunology, Female, Hormones immunology, Humans, Middle Aged, Neuroendocrine Tumors diagnosis, Unnecessary Procedures, Antibodies, Heterophile analysis, Hormones analysis, Rabbits immunology, Radioimmunoassay standards
Published
2003
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