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322 results on '"Dominguez, Lucas"'

6. SARS-CoV-2 Seroprevalence Studies in Pets, Spain

Author

Barroso-Arevalo, Sandra, Sanchez-Morales, Lidia, Barasona, Jose A., Dominguez, Lucas, and Sanchez-Vizcaino, Jose M.

Subjects
Statistics, Risk factors, Health aspects, Pets -- Statistics -- Health aspects, COVID-19 -- Statistics -- Risk factors, Zoonoses -- Statistics -- Risk factors
Abstract

Since December 2019, the entire world has experienced the pandemic produced by the novel beta-coronavirus SARS-CoV-2. This virus is the causative agent of COVID-19, a severe acute respiratory disease that [...]

Published
2023
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13. Good and bad get together: Inactivation of SARS-CoV-2 in particulate matter pollution from different fuels

Author

de la Fuente, José, Armas, Octavio, Barroso-Arévalo, Sandra, Gortázar, Christian, García-Seco, Teresa, Buendía-Andrés, Aránzazu, Villanueva, Florentina, Soriano, José A., Mazuecos, Lorena, Vaz-Rodrigues, Rita, García-Contreras, Reyes, García, Antonio, Monsalve-Serrano, Javier, Domínguez, Lucas, and Sánchez-Vizcaíno, José Manuel

Published
2022
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14. Zoonotic Transmission of Diphtheria from Domestic Animal Reservoir, Spain

Author

Hoefer, Andreas, Herrera-Leon, Silvia, Dominguez, Lucas, Gavin, Maria Ordobas, Romero, Beatriz, Piedra, Ximena Belen Araujo, Calzada, Cristina Sobrino, Gonzalez, Maria Jose Uria, and Herrera-Leon, Laura

Subjects
Case studies, Causes of, Health aspects, Disease transmission -- Case studies, Domestic animals -- Case studies -- Health aspects, Diphtheria -- Case studies -- Causes of, Zoonoses -- Case studies -- Causes of
Abstract

Diphtheria has been increasing in relevance because of increasing individual travel and surges in mass relocation events of refugees, asylum seekers, and immigrants from countries where diphtheria remains endemic (2-3). [...]

Published
2022
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25. Natural SARS-CoV-2 Infection in Kept Ferrets, Spain

Author

Gortazar, Christian, Barroso-Arevalo, Sandra, Ferreras-Colino, Elisa, Isla, Julio, de la Fuente, Gabriela, Rivera, Belen, Dominguez, Lucas, de la Fuente, Jose, and Sanchez-Vizcaino, Jose M.

Subjects
Development and progression, Risk factors, Health aspects, Pets -- Health aspects, Ferrets -- Health aspects, Human-animal relationships -- Health aspects, COVID-19 -- Risk factors -- Development and progression
Abstract

Natural infection of animals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported in pet cats and dogs, zoo felids and apes, and mustelids belonging to the subfamily [...]

Published
2021

32. Spatial dynamics of bovine tuberculosis in the Autonomous Community of Madrid, Spain (2010-2012).

Author

de la Cruz, Maria Luisa, Perez, Andres, Bezos, Javier, Pages, Enrique, Casal, Carmen, Carpintero, Jesus, Romero, Beatriz, Dominguez, Lucas, Barker, Christopher M, Diaz, Rosa, and Alvarez, Julio

Subjects
Animals, Cattle, Mycobacterium bovis, Tuberculosis, Bovine, Disease Outbreaks, Animal Husbandry, Spain, Molecular Typing, Tuberculosis, Bovine, General Science & Technology
Abstract

Progress in control of bovine tuberculosis (bTB) is often not uniform, usually due to the effect of one or more sometimes unknown epidemiological factors impairing the success of eradication programs. Use of spatial analysis can help to identify clusters of persistence of disease, leading to the identification of these factors thus allowing the implementation of targeted control measures, and may provide some insights of disease transmission, particularly when combined with molecular typing techniques. Here, the spatial dynamics of bTB in a high prevalence region of Spain were assessed during a three year period (2010-2012) using data from the eradication campaigns to detect clusters of positive bTB herds and of those infected with certain Mycobacterium bovis strains (characterized using spoligotyping and VNTR typing). In addition, the within-herd transmission coefficient (β) was estimated in infected herds and its spatial distribution and association with other potential outbreak and herd variables was evaluated. Significant clustering of positive herds was identified in the three years of the study in the same location ("high risk area"). Three spoligotypes (SB0339, SB0121 and SB1142) accounted for >70% of the outbreaks detected in the three years. VNTR subtyping revealed the presence of few but highly prevalent strains within the high risk area, suggesting maintained transmission in the area. The spatial autocorrelation found in the distribution of the estimated within-herd transmission coefficients in herds located within distances

Published
2014

33. Mortality and cardiovascular disease burden of uncontrolled diabetes in a registry-based cohort: the ESCARVAL-risk study

Author

Jorge Navarro-Pérez, Domingo Orozco-Beltran, Vicente Gil-Guillen, Vicente Pallares, Francisco Valls, Antonio Fernandez, Ana María Perez-Navarro, Carlos Sanchis, Alejandro Dominguez-Lucas, Jose M. Martin-Moreno, Josep Redon, Maria Tellez-Plaza, and on behalf of the ESCARVAL STUDY GROUP

Subjects
HbA1c, Diabetes, Attributable risk, All-cause mortality, Hospitalization, Coronary heart disease, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background Despite the epidemiological evidence about the relationship between diabetes, mortality and cardiovascular disease, information about the population impact of uncontrolled diabetes is scarce. We aimed to estimate the attributable risk associated with HbA1c levels for all-cause mortality and cardiovascular hospitalization. Methods Prospective study of subjects with diabetes mellitus using electronic health records from the universal public health system in the Valencian Community, Spain 2008–2012. We included 19,140 men and women aged 30 years or older with diabetes who underwent routine health examinations in primary care. Results A total of 11,003 (57%) patients had uncontrolled diabetes defined as HbA1c ≥6.5%, and, among those, 5325 participants had HbA1c ≥7.5%. During an average follow-up time of 3.3 years, 499 deaths, 912 hospitalizations for coronary heart disease (CHD) and 786 hospitalizations for stroke were recorded. We observed a linear and increasingly positive dose-response of HbA1c levels and CHD hospitalization. The relative risk for all-cause mortality and CHD and stroke hospitalization comparing patients with and without uncontrolled diabetes was 1.29 (95 CI 1.08,1.55), 1.38 (95 CI 1.20,1.59) and 1.05 (95 CI 0.91, 1.21), respectively. The population attributable risk (PAR) associated with uncontrolled diabetes was 13.6% (95% CI; 4.0–23.9) for all-cause mortality, 17.9% (95% CI; 10.5–25.2) for CHD and 2.7% (95% CI; − 5.5-10.8) for stroke hospitalization. Conclusions In a large general-practice cohort of patients with diabetes, uncontrolled glucose levels were associated with a substantial mortality and cardiovascular disease burden.

Published
2018
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40. Cohort profile: the Hortega Study for the evaluation of non-traditional risk factors of cardiometabolic and other chronic diseases in a general population from Spain

Author

Juan Carlos Martin-Escudero, Felipe Javier Chaves, Maria Tellez-Plaza, Laisa Briongos-Figuero, Gernot Pichler, Alejandro Dominguez-Lucas, Fernando Simal-Blanco, Francisco J Mena-Martin, Jesus Bellido-Casado, and Delfin Arzua-Mouronte

Subjects
Medicine
Abstract

PurposeThe Hortega Study is a prospective study, which investigates novel determinants of selected chronic conditions with an emphasis on cardiovascular health in a representative sample of a general population from Spain.ParticipantsIn 1997, a mailed survey was sent to a random selection of public health system beneficiaries assigned to the University Hospital Rio Hortega’s catchment area in Valladolid (Spain) (n=11 423, phase I), followed by a pilot examination in 1999–2000 of 495 phase I participants (phase II). In 2001–2003, the examination of 1502 individuals constituted the Hortega Study baseline examination visit (phase III, mean age 48.7 years, 49% men, 17% with obesity, 27% current smokers). Follow-up of phase III participants (also termed Hortega Follow-up Study) was obtained as of 30 November 2015 through review of health records (9.5% of participants without follow-up information).Findings to dateThe Hortega Study integrates baseline information of traditional and non-traditional factors (metabolomic including lipidomic and oxidative stress metabolites, genetic variants and environmental factors, such as metals), with 14 years of follow-up for the assessment of mortality and incidence of chronic diseases. Preliminary analysis of time to event data shows that well-known cardiovascular risk factors are associated with cardiovascular incidence rates, which add robustness to our cohort.Future plansIn 2020, we will review updated health and mortality records of this ongoing cohort for a 5-year follow-up extension. We will also re-examine elder survivors to evaluate specific aspects of ageing and conduct geolocation to study additional environmental exposures. Stored biological specimens are available for analysis of new biomarkers. The Hortega Study will, thus, enable the identification of novel factors based on time to event data, potentially contributing to the prevention and control of chronic diseases in ageing populations.

Published
2019
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44. Evidence for Human Adaptation and Foodborne Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus

Author

Larsen, Jesper, Stegger, Marc, Andersen, Paal S., Petersen, Andreas, Larsen, Anders R., Westh, Henrik, Agersø, Yvonne, Fetsch, Alexandra, Kraushaar, Britta, Käsbohrer, Annemarie, Feßler, Andrea T., Schwarz, Stefan, Cuny, Christiane, Witte, Wolfgang, Butaye, Patrick, Denis, Olivier, Haenni, Marisa, Madec, Jean-Yves, Jouy, Eric, Laurent, Frederic, Battisti, Antonio, Franco, Alessia, Alba, Patricia, Mammina, Caterina, Pantosti, Annalisa, Monaco, Monica, Wagenaar, Jaap A., de Boer, Enne, van Duijkeren, Engeline, Heck, Max, Domínguez, Lucas, Torres, Carmen, Zarazaga, Myriam, Price, Lance B., and Skov, Robert L.

Published
2016
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