225 results on '"Dole, William P."'
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2. Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension
3. Angiotensin receptor-neprilysin inhibition with LCZ696: a novel approach for the treatment of heart failure
4. Novel P2Y 12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): Pharmacodynamic and pharmacokinetic characterization
5. Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of Aliskiren in Healthy Chinese Subjects: A Randomized, Single-Blind, Parallel-Group, Placebo-Controlled Study
6. Clinical Pharmacokinetics and Pharmacodynamics of Aliskiren
7. Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren
8. Effects of Aliskiren, a Direct Renin Inhibitor, on Cardiac Repolarization and Conduction in Healthy Subjects
9. Vildagliptin, a Novel Dipeptidyl Peptidase IV Inhibitor, Has No Pharmacokinetic Interactions With the Antihypertensive Agents Amlodipine, Valsartan, and Ramipril in Healthy Subjects
10. Pharmacokinetics of the Oral Direct Renin Inhibitor Aliskiren Alone and in Combination with Irbesartan in Renal Impairment
11. Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers
12. Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers
13. Effect of clopidogrel on the steady-state pharmacokinetics of fluvastatin
14. Pharmacokinetics, safety, and tolerability of the novel oral direct renin inhibitor aliskiren in elderly healthy subjects
15. Pharmacokinetics, safety, and tolerability of the oral renin inhibitor aliskiren in patients with hepatic impairment
16. Hypertension in mice lacking the proatrial natriuretic peptide convertase corin
17. Standardization of outcome measures in clinical trials of pharmacological treatment for abdominal aortic aneurysm
18. Pharmacokinetics and Pharmacodynamics of Aliskiren/Hydrochlorothiazide Single-Pill Combination Tablets and Free Combination of Aliskiren and Hydrochlorothiazide
19. Influence of Body Weight and Gender on the Pharmacokinetics, Pharmacodynamics, and Antihypertensive Efficacy of Aliskiren
20. Hormonal and metabolic effects of morning or evening dosing of the dipeptidyl peptidase IV inhibitor vildagliptin in patients with type 2 diabetes
21. Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)
22. Pharmacokinetics and Pharmacodynamics of Vildagliptin in Healthy Chinese Volunteers
23. Characterization of a small molecule PAI-1 inhibitor, ZK4044
24. Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice
25. Pharmacokinetic Interaction of the Direct Renin Inhibitor Aliskiren with Furosemide and Extended-Release Isosorbide-5-Mononitrate in Healthy Subjects
26. The effect of age, gender, and body mass index on the pharmacokinetics and pharmacodynamics of vildagliptin in healthy volunteers
27. The Influence of Hepatic Impairment on the Pharmacokinetics of Vildagliptin: 2024-PO
28. Coupling of a New, Active Morphine Derivative to Sepharose for Affinity Chromatography
29. Angiotensin II Increases Urokinase-Type Plasminogen Activator Expression and Induces Aneurysm in the Abdominal Aorta of Apolipoprotein E-Deficient Mice
30. Failure of vasodilator infusion to alter pulmonary diffusing capacity in systemic sclerosis
31. Pharmacokinetics and pharmacodynamics of vildagliptin in healthy Chinese volunteers
32. Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL
33. Application of multianalyte microphysiometry to characterize macrophage metabolic responses to oxidized LDL and effects of an apoA-1 mimetic
34. Atrial natriuretic peptide regulates lipid mobilization and oxygen consumption in human adipocytes by activating AMPK
35. Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects
36. Total Cerebral Ischemia: Application of a New Model System To Studies of Cerebral Microcirculation
37. Total Cerebral Ischemia: A New Model System for the Study of Post-Cardiac Arrest Brain Damage
38. HORMONAL AND ELECTROLYTE RESPONSES TO THE ALDOSTERONE SYNTHASE INHIBITOR LCI699 IN SODIUM DEPLETED HEALTHY SUBJECTS
39. Study of the pharmacokinetic interaction of vildagliptin and metformin in patients with type 2 diabetes
40. A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects
41. Renal and Hormonal Responses to Direct Renin Inhibition With Aliskiren in Healthy Humans
42. Measurement of bioactive renin concentration and renin activity in the presence of exogenous renin substrate: effect of the oral direct renin inhibitor aliskiren
43. A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects
44. Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): Pharmacodynamic and pharmacokinetic characterization
45. Thiophene-Anthranilamides as Highly Potent and Orally Available Factor Xa Inhibitors
46. Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects
47. Pharmacokinetics of the Oral Direct??Renin Inhibitor Aliskiren Alone and??in Combination with Irbesartan in??Renal Impairment
48. Fasudil, a Rho-Kinase Inhibitor, Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm in Apolipoprotein E–Deficient Mice by Inhibiting Apoptosis and Proteolysis
49. Inhibition of Rho-Kinase by Hydroxyfasudil Prevents Vasopressin-Induced Myocardial Ischemia in Donryu Rats by Attenuating Coronary Vasoconstriction
50. Urokinase plasminogen activator receptor promotes macrophage infiltration into the vascular wall of ApoE deficient mice
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