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This article discusses the challenges of manually screening electroencephalogram (EEG) signals for emotion classification and proposes a novel automated method using Clefia pattern-based features. The proposed model achieves high accuracy in classifying arousal, dominance, and valence cases using two public databases. The Clefia pattern-based method offers low computational complexity and high accuracy for automated emotion classification using EEG signals. The text describes a database called DREAMER that contains EEG and ECG signals collected from 23 participants. The text also explains a proposed model for emotion classification using Clefia pattern and mRMR feature selection. The given text describes a method called Clefia pattern for extracting features from EEG signals. The method involves dividing the EEG signal into overlapping blocks and comparing each value in the signal with a corresponding value in a binary array. The resulting binary array is then divided into two groups and the decimal equivalent of each group is calculated. Finally, histograms of the EEG signal are generated using these decimal values and a feature vector is obtained by combining the histograms. The Clefia pattern is shown in a pseudocode algorithm and sample results of map generation and histogram operations are provided. The text describes a model for emotion classification that involves feature selection, classification using a support vector machine (SVM), and majority voting. The model is validated using two public databases and achieves high classification performance for arousal, valence, and dominance emotional states. The results are presented in tables, showing the performance metrics for each channel [Extracted from the article]

There are important unexplained points in cancer formation and its treatment with drugs. Some of the cancer drugs used in the treatment affect the genetic material of cancer cells. These types of drugs have a high toxicity. Despite important drugs used in cancer treatment have been developed today, there are serious problems in developing a drug with high specificity. This is because the pharmacological action points where drugs can affect cancerous cells and which are different from normal cells have not been fully determined. The current article reveals hypotheses about some extrachromosomal action points that may be beneficial in cancer treatment. Depending on the proposed hypothesis, information about the chemicals to be investigated is given. [ABSTRACT FROM AUTHOR]

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ahj.2004.10.039 Byline: Abdullah Dogan, Mustafa Ozgul, Mehmet Ozaydin, Suleyman M. Aslan, Omer Gedikli, Ahmet Altinbas Abstract: Current reperfusion strategies may fail to achieve optimal tissue perfusion in ST-elevation myocardial infarction (STEMI). We investigated the effect of clopidogrel plus aspirin on tissue perfusion and coronary flow in infarct patients treated with fibrinolytic agents. Author Affiliation: Department of Cardiology, Sevket Demirel Heart Center, Suleyman Demirel University, Isparta, Turkey Article History: Received 12 May 2004; Accepted 15 October 2004

Aim: It was aimed to determine antioxidant properties of extracts obtained from Allium czelghauricum, Lathyrus karsianus and Onosma nigricaule species and antioxidant effects of plant extracts on malathion-induced oxidant parameters in mice. Material and Method: Expermental animals were seperated into ten groups, each consisting of ten mice. First group was designed as a control group. Second group received 0.2 mL/kg of saline, and third group received the same dose of corn oil. Fourth (100 mg/kg malathion), fifth (100 mg/kg Allium czelghauricum), sixth (100 mg/kg Lathyrus karsianus), seventh (100 mg/kg Onosma nigricaule), eighth (100 mg/kg malathion+100 mg/kg Allium czelghauricum), ninth (100 mg/kg malathion+100 mg/kg Lathyrus karsianus) and the tenth group (100 mg/kg malathion+100 mg/kg Onosma nigricaule) were given daily intraperitoneally in the determined amounts. Applications were made for 21 days. After administration, total oxidant and total antioxidant capacities, body and liver weights, and histopathological changes in the liver were investigated in the serum and liver of mice. Results: It is observed that plant extracts significantly inhibit the dose dependent concentrations of nitric oxide radical. A high amount of polyphenolic compounds were detected in plant extracts. While applied malathion mice weighed lighter, an increase in their liver was observed. Pathological changes were found in the liver of mice given malathion in histopalogical examinations. Total oxidant capacity (TOC) of serum and liver was significantly higher compared with control group; however, a decrease was observed in total antioxidant capacity (TAC). While the TOC in the serum and liver of mice given malathion and plant extract decreased compared to the malathion group, it was found that there was an increase in TAC. Conclusion: In vitro study, it was revealed that methanol extracts of plants have antioxidant effects. In addition, it was determined that plant extracts exhibited antioxidant effects against the oxidant effect caused by malathion. [ABSTRACT FROM AUTHOR]