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5. Ciguatera or why you should enquire about fish consumption in cases of cold allodynia

Author

Friedemann, Miriam, Doberauer, Claus, Fink, Gereon R., Burghaus, Lothar, Friedemann, Miriam, Doberauer, Claus, Fink, Gereon R., and Burghaus, Lothar

Abstract

Ciguatoxins (CTX) are potent marine biotoxins produced by microalgae, which may accumulate seasonally, and which are locally variable in tropical predatory fish. Gastrointestinal, neurologic and/or cardiovascular symptoms occur shortly after the consumption of fish. Due to the high affinity of CTX to neuronal sodium channels, neurologic symptoms constitute a hallmark of ciguatera fish poisoning (CFP). Almost pathognomonic for CFP is an alteration of temperature perception (cold allodynia), in which cold surfaces are perceived as hot, painful, or produce dysesthesia (unpleasant, abnormal sensation). Increasing imports of tropical fish have led to more frequent reports of ciguatera in temperate climatic zones. We illustrate the specific features of CFP by reporting two cases due to imported tropical fish.

Published
2017

7. Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net

Author

Girschikofsky, Michael, primary, Arico, Maurizio, additional, Castillo, Diego, additional, Chu, Anthony, additional, Doberauer, Claus, additional, Fichter, Joachim, additional, Haroche, Julien, additional, Kaltsas, Gregory A, additional, Makras, Polyzois, additional, Marzano, Angelo V, additional, de Menthon, Mathilde, additional, Micke, Oliver, additional, Passoni, Emanuela, additional, Seegenschmiedt, Heinrich M, additional, Tazi, Abdellatif, additional, and McClain, Kenneth L, additional

Published
2013
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12. [Ciguatera or why you should enquire about fish consumption in cases of cold allodynia].

Author

Friedemann M, Doberauer C, Fink GR, and Burghaus L

Subjects
Adult, Animals, Ciguatera Poisoning complications, Ciguatera Poisoning therapy, Cold Temperature, Diuretics therapeutic use, Evidence-Based Medicine, Humans, Hyperalgesia etiology, Hyperalgesia therapy, Male, Mannitol therapeutic use, Middle Aged, Symptom Assessment, Thermosensing, Ciguatera Poisoning diagnosis, Fishes, Hyperalgesia diagnosis
Abstract

Ciguatoxine sind potente, von Mikroalgen produzierte, marine Biotoxine, die sich in tropischen Raubfischen, lokal und saisonal unterschiedlich stark, anreichern können. Kurze Zeit nach dem Fischverzehr treten gastrointestinale, neurologische und/oder kardiovaskuläre Vergiftungssymptome auf. Durch die hohe Affinität der Toxine zu neuronalen Natriumkanälen sind neurologische Symptome für Ciguatera-Vergiftungen charakteristisch. Nahezu pathognomonisch ist dabei die Kälteallodynie, bei der kalte Oberflächen als heiß, schmerzhaft oder extrem unangenehm empfunden werden. Durch Importe von Tropenfisch tritt Ciguatera zunehmend auch in gemäßigten Klimazonen auf. Wir erläutern anhand zweier Fälle die Besonderheiten dieser Fischvergiftung., Competing Interests: Interessenkonflikt: Die Autoren geben an, dass kein Interessenkonflikt besteht, (Georg Thieme Verlag KG Stuttgart · New York.)

Published
2017
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