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2. Patient and ward related risk factors in a multi-ward nosocomial outbreak of COVID-19: Outbreak investigation and matched case–control study

Author

Leal, Jenine, O’Grady, Heidi M., Armstrong, Logan, Dixit, Devika, Khawaja, Zoha, Snedeker, Kate, Ellison, Jennifer, Erebor, Joyce, Jamieson, Peter, Weiss, Amanda, Salcedo, Daniel, Roberts, Kimberley, Wiens, Karen, Croxen, Matthew A., Berenger, Byron M., Pabbaraju, Kanti, Lin, Yi-Chan, Evans, David, and Conly, John M.

Published
2023
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3. Virus kinetics and biochemical derangements among children with Ebolavirus disease

Author

Kjaldgaard, Lindsey, Claude, Kasereka Masumbuko, Mukadi-Bamuleka, Daniel, Kitenge-Omasumbu, Richard, Dixit, Devika, Edidi-Atani, François, Kuamfumu, Meris Matondo, Bulabula-Penge, Junior, Mambu-Mbika, Fabrice, Tshiani-Mbaya, Olivier, Diaz, Janet, Mulangu, Sabue, Legand, Anais, Mbala-Kingebeni, Placide, Formenty, Pierre, Ahuka-Mundeke, Steve, Muyembe-Tamfum, Jean-Jacques, and Hawkes, Michael T.

Published
2022
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5. Risk of transmission of respiratory viruses during aerosol-generating medical procedures (AGMPs) revisited in the COVID-19 pandemic: a systematic review

Author

Leal, Jenine, Farkas, Brenlea, Mastikhina, Liza, Flanagan, Jordyn, Skidmore, Becky, Salmon, Charleen, Dixit, Devika, Smith, Stephanie, Tsekrekos, Stephen, Lee, Bonita, Vayalumkal, Joseph, Dunn, Jessica, Harrison, Robyn, Cordoviz, Melody, Dubois, Roberta, Chandran, Uma, Clement, Fiona, Bush, Kathryn, Conly, John, and Larios, Oscar

Published
2022
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11. Disseminated alveolar echinococcosis in a 74-year-old woman presenting with focal seizure

Author

Olivier, Christopher J., Li, Hao, Auer, Roland N., and Dixit, Devika

Subjects
Meningioma -- Risk factors, Type 2 diabetes -- Care and treatment, Magnetic resonance imaging -- Usage, Health
Abstract

A 74-year-old woman with type 2 diabetes mellitus presented to hospital following new-onset focal seizure characterized by right-sided facial droop and numbness, with spread to the right eye and slurred [...]

Published
2019
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19. Asymptomatic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in adults is uncommon using rigorous symptom characterization and follow-up in an acute-care adult hospital outbreak

Author

O’Grady, Heidi M., primary, Dixit, Devika, additional, Khawaja, Zoha, additional, Snedeker, Kate, additional, Ellison, Jennifer, additional, Erebor, Joyce, additional, Jamieson, Peter, additional, Weiss, Amanda, additional, Salcedo, Daniel, additional, Roberts, Kimberley, additional, Wiens, Karen, additional, Etches, Nicholas, additional, Leal, Jenine, additional, and Conly, John M., additional

Published
2022
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20. Human and novel coronavirus infections in children: a review

Author

Rajapakse, Nipunie and Dixit, Devika

Subjects
Pediatrics, medicine.medical_specialty, ARDS, COVID-19 Vaccines, Adolescent, Middle East respiratory syndrome coronavirus, viruses, Severe Acute Respiratory Syndrome, medicine.disease_cause, Asymptomatic, Disease Outbreaks, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, 030225 pediatrics, Humans, Medicine, Pediatrics, Perinatology, and Child Health, 030212 general & internal medicine, Child, Respiratory tract infections, SARS-CoV-2, business.industry, Transmission (medicine), Infant, Newborn, COVID-19, Infant, virus diseases, medicine.disease, Intensive care unit, Systemic Inflammatory Response Syndrome, Child, Preschool, Pediatrics, Perinatology and Child Health, Middle East respiratory syndrome, Kawasaki disease, medicine.symptom, Coronavirus Infections, business
Abstract

Coronaviruses, seven of which are known to infect humans, can cause a spectrum of clinical presentations ranging from asymptomatic infection to severe illness and death. Four human coronaviruses (hCoVs)-229E, HKU1, NL63 and OC43-circulate globally, commonly infect children and typically cause mild upper respiratory tract infections. Three novel coronaviruses of zoonotic origin have emerged during the past two decades: severe acute respiratory syndrome coronavirus (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV) and the recently discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is the cause of the ongoing coronavirus disease 2019 (COVID-19) pandemic. These novel coronaviruses are known to cause severe illness and death predominantly in older adults and those with underlying comorbidities. Consistent with what has been observed during the outbreaks of SARS and MERS, children with COVID-19 are more likely to be asymptomatic or to have mild-to-moderate illness, with few deaths reported in children globally thus far. Clinical symptoms and laboratory and radiological abnormalities in children have been similar to those reported in adults but are generally less severe. A rare multisystem inflammatory syndrome in children (MIS-C) which has resulted in critical illness and some deaths has recently been described. Clinical trials for therapeutics and vaccine development should include paediatric considerations. Children may play an important role in the transmission of infection and outbreak dynamics and could be a key target population for effective measures to control outbreaks. The unintended consequences of the unprecedented scale and duration of pandemic control measures for children and families around the world should be carefully examined.Abbreviations: 2019-nCoV, 2019 novel coronavirus; ADEM, acute demyelinating encephalomyelitis; AAP, American Academy of Pediatrics; ACE-2, angiotensin-converting enzyme 2; ARDS, acute respiratory distress syndrome; BCG, bacillus Calmette-Guerin; BNP, brain natriuretic peptide; CDC, Centers for Disease Control and Prevention; CRP, C-reactive protein; CSF, cerebrospinal fluid; COVID-19, coronavirus disease 2019; CT, computed tomography; CXR, chest X-ray; DOL, day of life; hCoV, human coronavirus; ICU, intensive care unit; IL, interleukin; IVIG, intravenous immunoglobulin; KD, Kawasaki disease; LDH, lactate dehydrogenase; MERS, Middle East respiratory syndrome; MERS-CoV, Middle East respiratory syndrome coronavirus; MEURI, monitored emergency use of unregistered and experimental interventions; MIS-C, multi-system inflammatory syndrome in children; PCR, polymerase chain reaction; PICU, paediatric intensive care unit; RNA, ribonucleic acid; RCT, randomised-controlled trial; RSV, respiratory syncytial virus; SARS, severe acute respiratory syndrome; SARS-CoV-1, severe acute respiratory syndrome coronavirus 1; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TNF-alpha, tumour necrosis factor alpha; UK United Kingdom; UNICEF, United Nations Children's Fund; USA, United States of America; WHO, World Health Organization.

Published
2020
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21. Additional file 1 of Risk of transmission of respiratory viruses during aerosol-generating medical procedures (AGMPs) revisited in the COVID-19 pandemic: a systematic review

Author

Leal, Jenine, Farkas, Brenlea, Mastikhina, Liza, Flanagan, Jordyn, Skidmore, Becky, Salmon, Charleen, Dixit, Devika, Smith, Stephanie, Tsekrekos, Stephen, Lee, Bonita, Vayalumkal, Joseph, Dunn, Jessica, Harrison, Robyn, Cordoviz, Melody, Dubois, Roberta, Chandran, Uma, Clement, Fiona, Bush, Kathryn, Conly, John, and Larios, Oscar

Abstract

Additional file 1. Complete Search Strategy. Outlines the search strategies used across all databases.

Published
2022
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22. Additional file 3 of Risk of transmission of respiratory viruses during aerosol-generating medical procedures (AGMPs) revisited in the COVID-19 pandemic: a systematic review

Author

Leal, Jenine, Farkas, Brenlea, Mastikhina, Liza, Flanagan, Jordyn, Skidmore, Becky, Salmon, Charleen, Dixit, Devika, Smith, Stephanie, Tsekrekos, Stephen, Lee, Bonita, Vayalumkal, Joseph, Dunn, Jessica, Harrison, Robyn, Cordoviz, Melody, Dubois, Roberta, Chandran, Uma, Clement, Fiona, Bush, Kathryn, Conly, John, and Larios, Oscar

Abstract

Additional file 3. List of Excluded Studies. List of excluded studies and main reason for exclusion.

Published
2022
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23. Additional file 2 of Risk of transmission of respiratory viruses during aerosol-generating medical procedures (AGMPs) revisited in the COVID-19 pandemic: a systematic review

Author

Leal, Jenine, Farkas, Brenlea, Mastikhina, Liza, Flanagan, Jordyn, Skidmore, Becky, Salmon, Charleen, Dixit, Devika, Smith, Stephanie, Tsekrekos, Stephen, Lee, Bonita, Vayalumkal, Joseph, Dunn, Jessica, Harrison, Robyn, Cordoviz, Melody, Dubois, Roberta, Chandran, Uma, Clement, Fiona, Bush, Kathryn, Conly, John, and Larios, Oscar

Abstract

Additional file 2. List of AGMPs Considered in the Context of this Review. List of all the AGMPs considered in the context of this review, based on existing AGMP lists and by consensus from the Alberta Health Services’ AGMP guidance tool.

Published
2022
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24. The value of open-source clinical science in pandemic response: lessons from ISARIC

Author

Abbas, Ali, primary, Abdukahil, Sheryl Ann, additional, Abdulkadir, Nurul Najmee, additional, Abe, Ryuzo, additional, Abel, Laurent, additional, Absil, Lara, additional, Acharya, Subhash, additional, Acker, Andrew, additional, Adachi, Shingo, additional, Adam, Elisabeth, additional, Adrião, Diana, additional, Ageel, Saleh Al, additional, Ahmed, Shakeel, additional, Ain, Quratul, additional, Ainscough, Kate, additional, Aisa, Tharwat, additional, Ait Hssain, Ali, additional, Ait Tamlihat, Younes, additional, Akimoto, Takako, additional, Akmal, Ernita, additional, Al Qasim, Eman, additional, Alalqam, Razi, additional, Alam, Tanvir, additional, Al-dabbous, Tala, additional, Alegesan, Senthilkumar, additional, Alegre, Cynthia, additional, Alessi, Marta, additional, Alex, Beatrice, additional, Alexandre, Kévin, additional, Al-Fares, Abdulrahman, additional, Alfoudri, Huda, additional, Ali, Imran, additional, Ali Shah, Naseem, additional, Alidjnou, Kazali Enagnon, additional, Aliudin, Jeffrey, additional, Alkhafajee, Qabas, additional, Allavena, Clotilde, additional, Allou, Nathalie, additional, Altaf, Aneela, additional, Alves, João, additional, Alves, João Melo, additional, Alves, Rita, additional, Amaral, Maria, additional, Amira, Nur, additional, Ammerlaan, Heidi, additional, Ampaw, Phoebe, additional, Andini, Roberto, additional, Andrejak, Claire, additional, Angheben, Andrea, additional, Angoulvant, François, additional, Ansart, Séverine, additional, Anthonidass, Sivanesen, additional, Antonelli, Massimo, additional, Antunes de Brito, Carlos Alexandre, additional, Anwar, Kazi Rubayet, additional, Apriyana, Ardiyan, additional, Arabi, Yaseen, additional, Aragao, Irene, additional, Arali, Rajeshwari, additional, Arancibia, Francisco, additional, Araujo, Carolline, additional, Arcadipane, Antonio, additional, Archambault, Patrick, additional, Arenz, Lukas, additional, Arlet, Jean-Benoît, additional, Arnold-Day, Christel, additional, Aroca, Ana, additional, Arora, Lovkesh, additional, Arora, Rakesh, additional, Artaud-Macari, Elise, additional, Aryal, Diptesh, additional, Asaki, Motohiro, additional, Asensio, Angel, additional, Ashley, Elizabeth, additional, Ashraf, Muhammad, additional, Ashraf, Sheharyar, additional, Asim, Mohammad, additional, Assie, Jean Baptiste, additional, Asyraf, Amirul, additional, Atique, Anika, additional, Attanyake, AM Udara Lakshan, additional, Auchabie, Johann, additional, Aumaitre, Hugues, additional, Auvet, Adrien, additional, Azemar, Laurène, additional, Azoulay, Cecile, additional, Bach, Benjamin, additional, Bachelet, Delphine, additional, Badr, Claudine, additional, Baig, Nadia, additional, Baillie, J. Kenneth, additional, Baird, J Kevin, additional, Bak, Erica, additional, Bakakos, Agamemnon, additional, Bakar, Nazreen Abu, additional, Bal, Andriy, additional, Balakrishnan, Mohanaprasanth, additional, Balan, Valeria, additional, Bani-Sadr, Firouzé, additional, Barbalho, Renata, additional, Barbosa, Nicholas Yuri, additional, Barclay, Wendy S., additional, Barnett, Saef Umar, additional, Barnikel, Michaela, additional, Barrasa, Helena, additional, Barrelet, Audrey, additional, Barrigoto, Cleide, additional, Bartoli, Marie, additional, Bartone, Cheryl, additional, Baruch, Joaquín, additional, Bashir, Mustehan, additional, Basmaci, Romain, additional, Basri, Muhammad Fadhli Hassin, additional, Bastos, Diego, additional, Battaglini, Denise, additional, Bauer, Jules, additional, Bautista Rincon, Diego Fernando, additional, Bazan Dow, Denisse, additional, Bedossa, Alexandra, additional, Bee, Ker Hong, additional, Behilill, Sylvie, additional, Beishuizen, Albertus, additional, Beljantsev, Aleksandr, additional, Bellemare, David, additional, Beltrame, Anna, additional, Beltrão, Beatriz Amorim, additional, Beluze, Marine, additional, Benech, Nicolas, additional, Benjiman, Lionel Eric, additional, Benkerrou, Dehbia, additional, Bennett, Suzanne, additional, Bento, Luís, additional, Berdal, Jan-Erik, additional, Bergeaud, Delphine, additional, Bergin, Hazel, additional, Bernal Sobrino, José Luis, additional, Bertoli, Giulia, additional, Bertolino, Lorenzo, additional, Bessis, Simon, additional, Betz, Adam, additional, Bevilcaqua, Sybille, additional, Bezulier, Karine, additional, Bhatt, Amar, additional, Bhavsar, Krishna, additional, Bianchi, Isabella, additional, Bianco, Claudia, additional, Bidin, Farah Nadiah, additional, Bikram Singh, Moirangthem, additional, Bin Humaid, Felwa, additional, Bin Kamarudin, Mohd Nazlin, additional, Bissuel, François, additional, Biston, Patrick, additional, Bitker, Laurent, additional, Blanco-Schweizer, Pablo, additional, Blier, Catherine, additional, Bloos, Frank, additional, Blot, Mathieu, additional, Blumberg, Lucille, additional, Boccia, Filomena, additional, Bodenes, Laetitia, additional, Bogaarts, Alice, additional, Bogaert, Debby, additional, Boivin, Anne-Hélène, additional, Bolze, Pierre-Adrien, additional, Bompart, François, additional, Bonfasius, Aurelius, additional, Borges, Diogo, additional, Borie, Raphaël, additional, Bosse, Hans Martin, additional, Botelho-Nevers, Elisabeth, additional, Bouadma, Lila, additional, Bouchaud, Olivier, additional, Bouchez, Sabelline, additional, Bouhmani, Dounia, additional, Bouhour, Damien, additional, Bouiller, Kévin, additional, Bouillet, Laurence, additional, Bouisse, Camile, additional, Boureau, Anne-Sophie, additional, Bourke, John, additional, Bouscambert, Maude, additional, Bousquet, Aurore, additional, Bouziotis, Jason, additional, Boxma, Bianca, additional, Boyer-Besseyre, Marielle, additional, Boylan, Maria, additional, Bozza, Fernando Augusto, additional, Brack, Matthew, additional, Braconnier, Axelle, additional, Braga, Cynthia, additional, Brandenburger, Timo, additional, Brás Monteiro, Filipa, additional, Brazzi, Luca, additional, Breen, Dorothy, additional, Breen, Patrick, additional, Brett, Stephen, additional, Brickell, Kathy, additional, Broadley, Tessa, additional, Browne, Alex, additional, Browne, Shaunagh, additional, Brozzi, Nicolas, additional, Brusse-Keizer, Marjolein, additional, Buchtele, Nina, additional, Buesaquillo, Christian, additional, Bugaeva, Polina, additional, Buisson, Marielle, additional, Burhan, Erlina, additional, Burrell, Aidan, additional, Bustos, Ingrid G., additional, Butnaru, Denis, additional, Cabie, André, additional, Cabral, Susana, additional, Caceres, Eder, additional, Cadoz, Cyril, additional, Callahan, Mia, additional, Calligy, Kate, additional, Calvache, Jose Andres, additional, Cam, João, additional, Campana, Valentine, additional, Campbell, Paul, additional, Campisi, Josie, additional, Canepa, Cecilia, additional, Cantero, Mireia, additional, Caraux-Paz, Pauline, additional, Cárcel, Sheila, additional, Cardellino, Chiara Simona, additional, Cardoso, Filipa, additional, Cardoso, Filipe, additional, Cardoso, Nelson, additional, Cardoso, Sofia, additional, Carelli, Simone, additional, Carlier, Nicolas, additional, Carmoi, Thierry, additional, Carney, Gayle, additional, Carpenter, Chloe, additional, Carqueja, Inês, additional, Carret, Marie-Christine, additional, Carrier, François Martin, additional, Carroll, Ida, additional, Carson, Gail, additional, Carton, Ed, additional, Casanova, Maire-Laure, additional, Cascão, Mariana, additional, Casey, Siobhan, additional, Casimiro, José, additional, Cassandra, Bailey, additional, Castañeda, Silvia, additional, Castanheira, Nidyanara, additional, Castor-Alexandre, Guylaine, additional, Castrillón, Henry, additional, Castro, Ivo, additional, Catarino, Ana, additional, Catherine, François-Xavier, additional, Cattaneo, Paolo, additional, Cavalin, Roberta, additional, Cavalli, Giulio Giovanni, additional, Cavayas, Alexandros, additional, Ceccato, Adrian, additional, Cervantes-Gonzalez, Minerva, additional, Chair, Anissa, additional, Chakveatze, Catherine, additional, Chan, Adrienne, additional, Chand, Meera, additional, Chantalat Auger, Christelle, additional, Chapplain, Jean-Marc, additional, Chas, Julie, additional, Chaudary, Mobin, additional, Chávez Iñiguez, Jonathan Samuel, additional, Chen, Anjellica, additional, Chen, Yih-Sharng, additional, Cheng, Matthew Pellan, additional, Cheret, Antoine, additional, Chiarabini, Thibault, additional, Chica, Julian, additional, Chidambaram, Suresh Kumar, additional, Chin-Tho, Leong, additional, Chirouze, Catherine, additional, Chiumello, Davide, additional, Cho, Hwa Jin, additional, Cho, Sung-Min, additional, Cholley, Bernard, additional, Chopin, Marie-Charlotte, additional, Chow, Ting Soo, additional, Chow, Yock Ping, additional, Chua, Hiu Jian, additional, Chua, Jonathan, additional, Cidade, Jose Pedro, additional, Cisneros Herreros, José Miguel, additional, Citarella, Barbara Wanjiru, additional, Ciullo, Anna, additional, Clarke, Emma, additional, Clarke, Jennifer, additional, Claure Del Granado, Rolando, additional, Clohisey, Sara, additional, Cobb, J. Perren, additional, Coca, Necsoi, additional, Codan, Cassidy, additional, Cody, Caitriona, additional, Coelho, Alexandra, additional, Coles, Megan, additional, Colin, Gwenhaël, additional, Collins, Michael, additional, Colombo, Sebastiano Maria, additional, Combs, Pamela, additional, Connolly, Jennifer, additional, Connor, Marie, additional, Conrad, Anne, additional, Contreras, Sofía, additional, Conway, Elaine, additional, Cooke, Graham S., additional, Copland, Mary, additional, Cordel, Hugues, additional, Corley, Amanda, additional, Cormican, Sarah, additional, Cornelis, Sabine, additional, Cornet, Alexander Daniel, additional, Corpuz, Arianne Joy, additional, Cortegiani, Andrea, additional, Corvaisier, Grégory, additional, Costigan, Emma, additional, Couffignal, Camille, additional, Couffin-Cadiergues, Sandrine, additional, Courtois, Roxane, additional, Cousse, Stéphanie, additional, Cregan, Rachel, additional, Crepy D'Orleans, Charles, additional, Croonen, Sabine, additional, Crowl, Gloria, additional, Crump, Jonathan, additional, Cruz, Claudina, additional, Cruz Berm, Juan Luis, additional, Cruz Rojo, Jaime, additional, Csete, Marc, additional, Cucino, Alberto, additional, Cullen, Ailbhe, additional, Cullen, Caroline, additional, Cummings, Matthew, additional, Curley, Gerard, additional, Curlier, Elodie, additional, Curran, Colleen, additional, Custodio, Paula, additional, da Silva Filipe, Ana, additional, Da Silveira, Charlene, additional, Dabaliz, Al-Awwab, additional, Dagens, Andrew, additional, Dahly, Darren, additional, Dalton, Heidi, additional, Dalton, Jo, additional, Daly, Seamus, additional, D'Amico, Federico, additional, Daneman, Nick, additional, Daniel, Corinne, additional, Dankwa, Emmanuelle A, additional, Dantas, Jorge, additional, D’Aragon, Frédérick, additional, de Boer, Mark, additional, de Loughry, Gillian, additional, de Mendoza, Diego, additional, De Montmollin, Etienne, additional, de Oliveira França, Rafael Freitas, additional, de Pinho Oliveira, Ana Isabel, additional, De Rosa, Rosanna, additional, de Silva, Thushan, additional, de Vries, Peter, additional, Deacon, Jillian, additional, Dean, David, additional, Debard, Alexa, additional, DeBenedictis, Bianca, additional, Debray, Marie-Pierre, additional, DeCastro, Nathalie, additional, Dechert, William, additional, Deconninck, Lauren, additional, Decours, Romain, additional, Defous, Eve, additional, Delacroix, Isabelle, additional, Delaveuve, Eric, additional, Delavigne, Karen, additional, Delfos, Nathalie M., additional, Deligiannis, Ionna, additional, Dell'Amore, Andrea, additional, Delmas, Christelle, additional, Delobel, Pierre, additional, Delsing, Corine, additional, Demonchy, Elisa, additional, Denis, Emmanuelle, additional, Deplanque, Dominique, additional, Depuydt, Pieter, additional, Desai, Mehul, additional, Descamps, Diane, additional, Desvallée, Mathilde, additional, Dewayanti, Santi, additional, Diallo, Alpha, additional, Diamantis, Sylvain, additional, Dias, André, additional, Diaz, Priscila, additional, Diaz, Rodrigo, additional, Diaz Diaz, Juan Jose, additional, Didier, Kévin, additional, Diehl, Jean-Luc, additional, Dieperink, Wim, additional, Dimet, Jérôme, additional, Dinot, Vincent, additional, Diop, Fara, additional, Diouf, Alphonsine, additional, Dishon, Yael, additional, Dixit, Devika, additional, Djossou, Félix, additional, Docherty, Annemarie B., additional, Doherty, Helen, additional, Dondorp, Arjen M, additional, Dong, Andy, additional, Donnelly, Christl A., additional, Donnelly, Maria, additional, Donohue, Chloe, additional, Donohue, Sean, additional, Donohue, Yoann, additional, Doran, Ciara, additional, Doran, Peter, additional, Dorival, Céline, additional, D'Ortenzio, Eric, additional, Douglas, James Joshua, additional, Douma, Renee, additional, Dournon, Nathalie, additional, Downer, Triona, additional, Downey, Joanne, additional, Downing, Mark, additional, Drake, Tom, additional, Driscoll, Aoife, additional, Dryden, Murray, additional, Duarte Fonseca, Claudio, additional, Dubee, Vincent, additional, Dubos, François, additional, Ducancelle, Alexandre, additional, Duculan, Toni, additional, Dudman, Susanne, additional, Duggal, Abhijit, additional, Dunand, Paul, additional, Dunning, Jake, additional, Duplaix, Mathilde, additional, Durante-Mangoni, Emanuele, additional, Durham III, Lucian, additional, Dussol, Bertrand, additional, Duthoit, Juliette, additional, Duval, Xavier, additional, Dyrhol-Riise, Anne Margarita, additional, Ean, Sim Choon, additional, Echeverria-Villalobos, Marco, additional, Egan, Siobhan, additional, Eira, Carla, additional, El Sanharawi, Mohammed, additional, Elapavaluru, Subbarao, additional, Elharrar, Brigitte, additional, Ellerbroek, Jacobien, additional, Eloy, Philippine, additional, Elshazly, Tarek, additional, Elyazar, Iqbal, additional, Enderle, Isabelle, additional, Endo, Tomoyuki, additional, Eng, Chan Chee, additional, Engelmann, Ilka, additional, Enouf, Vincent, additional, Epaulard, Olivier, additional, Escher, Martina, additional, Esperatti, Mariano, additional, Esperou, Hélène, additional, Esposito-Farese, Marina, additional, Estevão, João, additional, Etienne, Manuel, additional, Ettalhaoui, Nadia, additional, Everding, Anna Greti, additional, Evers, Mirjam, additional, Fabre, Isabelle, additional, Fabre, Marc, additional, Faheem, Amna, additional, Fahy, Arabella, additional, Fairfield, Cameron J., additional, Fakar, Zul, additional, Faria, Pedro, additional, Farooq, Ahmed, additional, Farrar, Jeremy J., additional, Farshait, Nataly, additional, Fateena, Hanan, additional, Fatoni, Arie Zainul, additional, Faure, Karine, additional, Favory, Raphaël, additional, Fayed, Mohamed, additional, Feely, Niamh, additional, Feeney, Laura, additional, Fernandes, Jorge, additional, Fernandes, Marília, additional, Fernandes, Susana, additional, Ferrand, François-Xavier, additional, Ferrand Devouge, Eglantine, additional, Ferrão, Joana, additional, Ferraz, Mário, additional, Ferreira, Benigno, additional, Ferreira, Sílvia, additional, Ferrer-Roca, Ricard, additional, Ferriere, Nicolas, additional, Ficko, Céline, additional, Figueiredo-Mello, Claudia, additional, Fiorda, Juan, additional, Flament, Thomas, additional, Flateau, Clara, additional, Fletcher, Tom, additional, Florio, Letizia Lucia, additional, Flynn, Brigid, additional, Flynn, Deirdre, additional, Foley, Claire, additional, Foley, Jean, additional, Fomin, Victor, additional, Fonseca, Tatiana, additional, Fontela, Patricia, additional, Forsyth, Simon, additional, Foster, Denise, additional, Foti, Giuseppe, additional, Fourn, Erwan, additional, Fowler, Robert A., additional, Fraher, Dr Marianne, additional, Franch-Llasat, Diego, additional, Fraser, Christophe, additional, Fraser, John F., additional, Freire, Marcela Vieira, additional, Freitas Ribeiro, Ana, additional, Friedrich, Caren, additional, Fritz, Ricardo, additional, Fry, Stéphanie, additional, Fuentes, Nora, additional, Fukuda, Masahiro, additional, Gaborieau, Valérie, additional, Gaci, Rostane, additional, Gagliardi, Massimo, additional, Gagnard, Jean-Charles, additional, Gagné, Nathalie, additional, Gagneux-Brunon, Amandine, additional, Gaião, Sérgio, additional, Gail Skeie, Linda, additional, Gallagher, Phil, additional, Gallego Curto, Elena, additional, Gamble, Carrol, additional, Gani, Yasmin, additional, Garan, Arthur, additional, Garcia, Rebekha, additional, García Barrio, Noelia, additional, Garcia-Diaz, Julia, additional, Garcia-Gallo, Esteban, additional, Garimella, Navya, additional, Garot, Denis, additional, Garrait, Valérie, additional, Gauli, Basanta, additional, Gault, Nathalie, additional, Gavin, Aisling, additional, Gavrylov, Anatoliy, additional, Gaymard, Alexandre, additional, Gebauer, Johannes, additional, Geraud, Eva, additional, Gerbaud Morlaes, Louis, additional, Germano, Nuno, additional, ghisulal, praveen kumar, additional, Ghosn, Jade, additional, Giani, Marco, additional, Giaquinto, Carlo, additional, Gibson, Jess, additional, Gigante, Tristan, additional, Gilg, Morgane, additional, Gilroy, Elaine, additional, Giordano, Guillermo, additional, Girvan, Michelle, additional, Gissot, Valérie, additional, Gitahi, Judy, additional, Giwangkancana, Gezy, additional, Glikman, Daniel, additional, Glybochko, Petr, additional, Gnall, Eric, additional, Goco, Geraldine, additional, Goehringer, François, additional, Goepel, Siri, additional, Goffard, Jean-Christophe, additional, Goh, Jin Yi, additional, Golob, Jonathan, additional, Gomes, Rui, additional, Gomez, Kyle, additional, Gómez-Junyent, Joan, additional, Gominet, Marie, additional, Gonzalez, Alicia, additional, Gordon, Patricia, additional, Gordon, Anthony, additional, Gorenne, Isabelle, additional, Goubert, Laure, additional, Goujard, Cécile, additional, Goulenok, Tiphaine, additional, Grable, Margarite, additional, Graf, Jeronimo, additional, Grandin, Edward Wilson, additional, Granier, Pascal, additional, Grasselli, Giacomo, additional, Grazioli, Lorenzo, additional, Green, Christopher A., additional, Greene, Courtney, additional, Greenhalf, William, additional, Greffe, Segolène, additional, Grieco, Domenico Luca, additional, Griffee, Matthew, additional, Griffiths, Fiona, additional, Grigoras, Ioana, additional, Groenendijk, Albert, additional, Grosse Lordemann, Anja, additional, Gruner, Heidi, additional, Gu, Yusing, additional, Guarracino, Fabio, additional, Guedj, Jérémie, additional, Guego, Martin, additional, Guellec, Dewi, additional, Guerguerian, Anne-Marie, additional, Guerreiro, Daniela, additional, Guery, Romain, additional, Guillaumot, Anne, additional, Guilleminault, Laurent, additional, Guimarães de Castro, Maisa, additional, Guimard, Thomas, additional, Haalboom, Marieke, additional, Haber, Daniel, additional, Habraken, Hannah, additional, Hachemi, Ali, additional, Hadri, Nadir, additional, Haidash, Olena, additional, Haider, Saeeda, additional, Haidri, Fakhir, additional, Hakak, Sheeba, additional, Hall, Adam, additional, Hall, Matthew, additional, Halpin, Sophie, additional, Hamer, Ansley, additional, Hamers, Raph, additional, Hamidfar, Rebecca, additional, Hammond, Terese, additional, Han, Lim Yuen, additional, Haniffa, Rashan, additional, Hao, Kok Wei, additional, Hardwick, Hayley, additional, Harrison, Ewen M., additional, Harrison, Janet, additional, Harrison, Samuel Bernard Ekow, additional, Hartman, Alan, additional, Hashmi, Junaid, additional, Hashmi, Madiha, additional, Hayat, Muhammad, additional, Hayes, Ailbhe, additional, Hays, Leanne, additional, Heerman, Jan, additional, Heggelund, Lars, additional, Hendry, Ross, additional, Hennessy, Martina, additional, Henriquez, Aquiles, additional, Hentzien, Maxime, additional, Herekar, Fivzia, additional, Hernandez-Montfort, Jaime, additional, Herr, Daniel, additional, Hershey, Andrew, additional, Hesstvedt, Liv, additional, Hidayah, Astarini, additional, Higgins, Dawn, additional, Higgins, Eibhilin, additional, HigginsOKeeffe, Grainne, additional, Hinchion, Rita, additional, Hinton, Samuel, additional, Hiraiwa, Hiroaki, additional, Hitoto, Hikombo, additional, Ho, Antonia, additional, Ho, Yi Bin, additional, Hoctin, Alexandre, additional, Hoffmann, Isabelle, additional, Hoh, Wei Han, additional, Hoiting, Oscar, additional, Holt, Rebecca, additional, Holter, Jan Cato, additional, Horby, Peter, additional, Horcajada, Juan Pablo, additional, Hoshino, Koji, additional, Hoshino, Kota, additional, Houas, Ikram, additional, Hough, Catherine L., additional, Houltham, Stuart, additional, Hsu, Jimmy Ming-Yang, additional, Hulot, Jean-Sébastien, additional, Hussain, Iqbal, additional, Ijaz, Samreen, additional, Illes, Hajnal-Gabriela, additional, Imbert, Patrick, additional, Imran, Mohammad, additional, Imran Sikander, Rana, additional, Inácio, Hugo, additional, Infante Dominguez, Carmen, additional, Ing, Yun Sii, additional, Iosifidis, Elias, additional, Ippolito, Mariachiara, additional, Isgett, Sarah, additional, Ishani, Palliya Guruge Pramodya Ishani, additional, Isidoro, Tiago, additional, Ismail, Nadiah, additional, Isnard, Margaux, additional, Itai, Junji, additional, Ito, Asami, additional, Ivulich, Daniel, additional, Jaafar, Danielle, additional, Jaafoura, Salma, additional, Jabot, Julien, additional, Jackson, Clare, additional, Jamieson, Nina, additional, Jaquet, Pierre, additional, Jassat, Waasila, additional, Jaud-Fischer, Coline, additional, Jaureguiberry, Stéphane, additional, Javidfar, Jeffrey, additional, Jawad, Issrah, additional, Jaworsky, Denise, additional, Jayakumar, Devachandran, additional, Jego, Florence, additional, Jelani, Anilawati Mat, additional, Jenum, Synne, additional, Jimbo-Sotomayor, Ruth, additional, Job, van der Palen, additional, Joe, Ong Yiaw, additional, Jorge García, Ruth N., additional, Joseph, Cédric, additional, Joseph, Mark, additional, Joshi, Swosti, additional, Jourdain, Mercé, additional, Jouvet, Philippe, additional, June, Jennifer, additional, Jung, Anna, additional, Jung, Hanna, additional, Juzar, Dafsah, additional, Kafif, Ouifiya, additional, Kaguelidou, Florentia, additional, Kaisbain, Neerusha, additional, Kaleesvran, Thavamany, additional, Kali, Sabina, additional, Kalicinska, Alina, additional, Kalomoiri, Smaragdi, additional, Kamal, Saima, additional, Kamaluddin, Muhammad Aisar Ayadi, additional, Kamaruddin, Zul Amali Che, additional, Kamarudin, Nadiah, additional, Kandamby, Darshana Hewa, additional, Kandel, Chris, additional, Kang, Kong Yeow, additional, Kant, Ravi, additional, Kanwal, Darakhshan, additional, Kanyawati, Dyah, additional, Karki, Bipin, additional, Karpayah, Pratap, additional, Karsies, Todd, additional, Kartsonaki, Christiana, additional, Kasugai, Daisuke, additional, Kataria, Anant, additional, Katz, Kevin, additional, Kaur, Aasmine, additional, Kaur Johal, Simreen, additional, Kawasaki, Tatsuya, additional, Kay, Christy, additional, Keane, Hannah, additional, Keating, Seán, additional, Kellam, Paul, additional, Kelly, Andrea, additional, Kelly, Aoife, additional, Kelly, Claire, additional, Kelly, Niamh, additional, Kelly, Sadie, additional, Kelly, Yvelynne, additional, Kelsey, Maeve, additional, Kennedy, Ryan, additional, Kennon, Kalynn, additional, Kernan, Maeve, additional, Kerroumi, Younes, additional, Keshav, Sharma, additional, Kestelyn, Evelyne, additional, Khalid, Imrana, additional, Khalid, Osama, additional, Khalil, Antoine, additional, Khan, Coralie, additional, Khan, Irfan, additional, Khanal, Sushil, additional, Kho, Michelle E, additional, Khoo, Denisa, additional, Khoo, Ryan, additional, Khoo, Saye, additional, Khoso, Nasir, additional, Kiat, Khor How, additional, Kida, Yuri, additional, Kiiza, Peter, additional, Kildal, Anders Benjamin, additional, Kim, Jae Burm, additional, Kimmoun, Antoine, additional, Kindgen-Milles, Detlef, additional, King, Alexander, additional, Kitamura, Nobuya, additional, Klenerman, Paul, additional, Klont, Rob, additional, Kloumann Bekken, Gry, additional, Knight, Stephen, additional, Kobbe, Robin, additional, Kodippily, Chamira, additional, Kohns Vasconcelos, Malte, additional, Koirala, Sabin, additional, Komatsu, Mamoru, additional, Korten, Volkan, additional, Kosgei, Caroline, additional, Kpangon, Arsène, additional, Krawczyk, Karolina, additional, Krishnan, Sudhir, additional, Krishnan, Vinothini, additional, Kruglova, Oksana, additional, Kumar, Ashok, additional, Kumar, Deepali, additional, Kumar, Ganesh, additional, Kumar, Mukesh, additional, Kumar Vecham, Pavan, additional, Kuriakose, Dinesh, additional, Kurtzman, Ethan, additional, Kusumastuti, Neurinda Permata, additional, Kutsogiannis, Demetrios, additional, Kutsyna, Galyna, additional, Kyriakoulis, Konstantinos, additional, Lachatre, Marie, additional, Lacoste, Marie, additional, Laffey, John G., additional, Lagrange, Marie, additional, Laine, Fabrice, additional, Lairez, Olivier, additional, Lakhey, Sanjay, additional, Lalueza, Antonio, additional, Lambert, Marc, additional, Lamontagne, François, additional, Langelot-Richard, Marie, additional, Langlois, Vincent, additional, Lantang, Eka Yudha, additional, Lanza, Marina, additional, Laouénan, Cédric, additional, Laribi, Samira, additional, Lariviere, Delphine, additional, Lasry, Stéphane, additional, Latif, Naveed, additional, Launay, Odile, additional, Laureillard, Didier, additional, Lavie-Badie, Yoan, additional, Law, Andy, additional, Lawrence, Cassie, additional, Lawrence, Teresa, additional, Le, Minh, additional, Le Bihan, Clément, additional, Le Bris, Cyril, additional, Le Falher, Georges, additional, Le Fevre, Lucie, additional, Le Hingrat, Quentin, additional, Le Maréchal, Marion, additional, Le Mestre, Soizic, additional, Le Moal, Gwenaël, additional, Le Moing, Vincent, additional, Le Nagard, Hervé, additional, Le Turnier, Paul, additional, Leal, Ema, additional, Leal Santos, Marta, additional, Lee, Biing Horng, additional, Lee, Heng Gee, additional, Lee, James, additional, Lee, Su Hwan, additional, Lee, Todd C., additional, Lee, Yi Lin, additional, Leeming, Gary, additional, Lefebvre, Bénédicte, additional, Lefebvre, Laurent, additional, Lefevre, Benjamin, additional, LeGac, Sylvie, additional, Lelievre, Jean-Daniel, additional, Lellouche, François, additional, Lemaignen, Adrien, additional, Lemee, Véronique, additional, Lemeur, Anthony, additional, Lemmink, Gretchen, additional, Lene, Ha Sha, additional, Lennon, Jenny, additional, León, Rafael, additional, Leone, Marc, additional, Leone, Michela, additional, Lepiller, Quentin, additional, Lescure, François-Xavier, additional, Lesens, Olivier, additional, Lesouhaitier, Mathieu, additional, Lester-Grant, Amy, additional, Levy, Bruno, additional, Levy, Yves, additional, Levy-Marchal, Claire, additional, Lewandowska, Katarzyna, additional, L'Her, Erwan, additional, Li Bassi, Gianluigi, additional, Liang, Janet, additional, Liaquat, Ali, additional, Liegeon, Geoffrey, additional, Lim, Kah Chuan, additional, Lim, Wei Shen, additional, Lima, Chantre, additional, Lina, Bruno, additional, Lina, Lim, additional, Lind, Andreas, additional, Lingas, Guillaume, additional, Lion-Daolio, Sylvie, additional, Lissauer, Samantha, additional, Liu, Keibun, additional, Livrozet, Marine, additional, Lizotte, Patricia, additional, Loforte, Antonio, additional, Lolong, Navy, additional, Loon, Leong Chee, additional, Lopes, Diogo, additional, Lopez-Colon, Dalia, additional, Loschner, Anthony L., additional, Loubet, Paul, additional, Loufti, Bouchra, additional, Louis, Guillame, additional, Lourenco, Silvia, additional, Lovelace-Macon, Lara, additional, Low, Lee Lee, additional, Lowik, Marije, additional, Loy, Jia Shyi, additional, Lucet, Jean Christophe, additional, Lumbreras Bermejo, Carlos, additional, Luna, Carlos M., additional, Lungu, Olguta, additional, Luong, Liem, additional, Luque, Nestor, additional, Luton, Dominique, additional, Lwin, Nilar, additional, Lyons, Ruth, additional, Maasikas, Olavi, additional, Mabiala, Oryane, additional, MacDonald, Samual, additional, MacDonald, Sarah, additional, Machado, Moïse, additional, Macheda, Gabriel, additional, Macias Sanchez, Juan, additional, Madhok, Jai, additional, Maestro de la Calle, Guillermo, additional, Mahieu, Rafael, additional, Mahy, Sophie, additional, Maia, Ana Raquel, additional, Maier, Lars S., additional, Maillet, Mylène, additional, Maitre, Thomas, additional, Malfertheiner, Maximilian, additional, Malik, Nadia, additional, Mallon, Paddy, additional, Maltez, Fernando, additional, Malvy, Denis, additional, Manda, Victoria, additional, Mandei, Jose M., additional, Mandelbrot, Laurent, additional, Manetta, Frank, additional, Mangal, Kishore, additional, Mankikian, Julie, additional, Manning, Edmund, additional, Manuel, Aldric, additional, Maria Sant`Ana Malaque, Ceila, additional, Marino, Daniel, additional, Marino, Flávio, additional, Markowicz, Samuel, additional, Maroun Eid, Charbel, additional, Marques, Ana, additional, Marquis, Catherine, additional, Marsh, Brian, additional, Marsh, Laura, additional, Marshal, Megan, additional, Marshall, John, additional, Martelli, Celina Turchi, additional, Martin, Dori-Ann, additional, Martin, Emily, additional, Martin-Blondel, Guillaume, additional, Martinelli, Alessandra, additional, Martin-Loeches, Ignacio, additional, Martinot, Martin, additional, Martin-Quiros, Alejandro, additional, Martins, Ana, additional, Martins, João, additional, Martins, Nuno, additional, Martins Rego, Caroline, additional, Martucci, Gennaro, additional, Martynenko, Olga, additional, Marwali, Eva Miranda, additional, Marzukie, Marsilla, additional, Masa Jimenez, Juan Fernado, additional, Maslove, David, additional, Mason, Phillip, additional, Mason, Sabina, additional, Masood, Sobia, additional, Mat Nor, Basri, additional, Matan, Moshe, additional, Mateus Fernandes, Henrique, additional, Mathew, Meghena, additional, Mathieu, Daniel, additional, Mattei, Mathieu, additional, Matulevics, Romans, additional, Maulin, Laurence, additional, Maxwell, Michael, additional, Maynar, Javier, additional, Mazzoni, Thierry, additional, Mc Sweeney, Lisa, additional, McAndrew, Lorraine, additional, McArthur, Colin, additional, McCarthy, Aine, additional, McCarthy, Anne, additional, McCloskey, Colin, additional, McConnochie, Rachael, additional, McDermott, Sherry, additional, McDonald, Sarah E., additional, McElroy, Aine, additional, McElwee, Samuel, additional, McEneany, Victoria, additional, McEvoy, Natalie, additional, McGeer, Allison, additional, McKay, Chris, additional, McKeown, Johnny, additional, McLean, Kenneth A., additional, McNally, Paul, additional, McNicholas, Bairbre, additional, McPartlan, Elaine, additional, Meaney, Edel, additional, Mear-Passard, Cécile, additional, Mechlin, Maggie, additional, Meher, Maqsood, additional, Mehkri, Omar, additional, Mele, Ferruccio, additional, Melo, Luis, additional, Memon, Kashif, additional, Mendes, Joao Joao, additional, Menkiti, Ogechukwu, additional, Menon, Kusum, additional, Mentré, France, additional, Mentzer, Alexander J., additional, Mercier, Emmanuelle, additional, Mercier, Noémie, additional, Merckx, Antoine, additional, Mergeay-Fabre, Mayka, additional, Mergler, Blake, additional, Merson, Laura, additional, Mesquita, António, additional, Metwally, Osama, additional, Meybeck, Agnès, additional, Meyer, Dan, additional, Meynert, Alison M., additional, Meysonnier, Vanina, additional, Meziane, Amina, additional, Mezidi, Mehdi, additional, Michelagnoli, Giuliano, additional, Michelanglei, Céline, additional, Michelet, Isabelle, additional, Mihelis, Efstathia, additional, Mihnovit, Vladislav, additional, Miranda-Maldonado, Hugo, additional, Misnan, Nor Arisah, additional, Mohamed, Nik Nur Eliza, additional, Mohamed, Tahira Jamal, additional, Moin, Asma, additional, Molina, David, additional, Molinos, Elena, additional, Molloy, Brenda, additional, Mone, Mary, additional, Monteiro, Agostinho, additional, Montes, Claudia, additional, Montrucchio, Giorgia, additional, Moore, Sarah, additional, Moore, Shona C., additional, Morales Cely, Lina, additional, Moro, Lucia, additional, Morocho Tutillo, Diego Rolando, additional, Morton, Ben, additional, Motherway, Catherine, additional, Motos, Ana, additional, Mouquet, Hugo, additional, Mouton Perrot, Clara, additional, Moyet, Julien, additional, Mudara, Caroline, additional, Mufti, Aisha Kalsoom, additional, Muh, Ng Yong, additional, Muhamad, Dzawani, additional, Mullaert, Jimmy, additional, Muller, Fredrik, additional, Müller, Karl Erik, additional, Munblit, Daniel, additional, Muneeb, Syed, additional, Munir, Nadeem, additional, Munshi, Laveena, additional, Murphy, Aisling, additional, Murphy, Lorna, additional, Murris, Marlène, additional, Murthy, Srinivas, additional, Musaab, Himed, additional, Muyandy, Gugapriyaa, additional, Myrodia, Dimitra Melia, additional, N, Namra, additional, Nagpal, Dave, additional, Nagrebetsky, Alex, additional, Narasimhan, Mangala, additional, Narayanan, Nageswaran, additional, Nasim Khan, Rashid, additional, Nazerali-Maitland, Alasdair, additional, Neant, Nadège, additional, Neb, Holger, additional, Nekliudov, Nikita A, additional, Nelwan, Erni, additional, Neto, Raul, additional, Neumann, Emily, additional, Neves, Bernardo, additional, Ng, Pauline Yeung, additional, Nghi, Anthony, additional, Nguyen, Duc, additional, Ni Choileain, Orna, additional, Ni Leathlobhair, Niamh, additional, Nichol, Alistair, additional, Nitayavardhana, Prompak, additional, Nonas, Stephanie, additional, Noordin, Nurul Amani Mohd, additional, Noret, Marion, additional, Norharizam, Nurul Faten Izzati, additional, Norman, Lisa, additional, Notari, Alessandra, additional, Noursadeghi, Mahdad, additional, Nowicka, Karolina, additional, Nowinski, Adam, additional, Nseir, Saad, additional, Nunez, Jose I, additional, Nurnaningsih, Nurnaningsih, additional, Nyamankolly, Elsa, additional, O Brien, Fionnuala, additional, O'Callaghan, Annmarie, additional, Occhipinti, Giovanna, additional, OConnor, Derbrenn, additional, O'Donnell, Max, additional, Ogston, Tawnya, additional, Ogura, Takayuki, additional, Oh, Tak-Hyuk, additional, O'Halloran, Sophie, additional, O'Hearn, Katie, additional, Ohshimo, Shinichiro, additional, Oldakowska, Agnieszka, additional, Oliveira, João, additional, Oliveira, Larissa, additional, Olliaro, Piero L., additional, O'Neil, Conar, additional, Ong, David S.Y., additional, Ong, Jee Yan, additional, Oosthuyzen, Wilna, additional, Opavsky, Anne, additional, Openshaw, Peter, additional, Orakzai, Saijad, additional, Orozco-Chamorro, Claudia Milena, additional, Orquera, Andrés, additional, Ortoleva, Jamel, additional, Osatnik, Javier, additional, O'Shea, Linda, additional, O'Sullivan, Miriam, additional, Othman, Siti Zubaidah, additional, Ouamara, Nadia, additional, Ouissa, Rachida, additional, Owyang, Clark, additional, Oziol, Eric, additional, Pabasara, H M Upulee, additional, Pagadoy, Maïder, additional, Pages, Justine, additional, Palacios, Amanda, additional, Palacios, Mario, additional, Palmarini, Massimo, additional, Panarello, Giovanna, additional, Panda, Prasan Kumar, additional, Paneru, Hem, additional, Pang, Lai Hui, additional, Panigada, Mauro, additional, Pansu, Nathalie, additional, Papadopoulos, Aurélie, additional, Parke, Rachael, additional, Parker, Melissa, additional, Parra, Briseida, additional, Parrini, Vieri, additional, Pasha, Taha, additional, Pasquier, Jérémie, additional, Pastene, Bruno, additional, Patauner, Fabian, additional, Patel, Junaid, additional, Pathmanathan, Mohan Dass, additional, Patrão, Luís, additional, Patricio, Patricia, additional, Patrier, Juliette, additional, Patterson, Lisa, additional, Pattnaik, Rajyabardhan, additional, Paul, Christelle, additional, Paul, Mical, additional, Paulos, Jorge, additional, Paxton, William A., additional, Payen, Jean-François, additional, Peariasamy, Kalaiarasu, additional, Pedrera Jiménez, Miguel, additional, Peek, Giles J., additional, Peelman, Florent, additional, Peiffer-Smadja, Nathan, additional, Peigne, Vincent, additional, Pejkovska, Mare, additional, Pelosi, Paolo, additional, Peltan, Ithan D., additional, Pereira, Rui, additional, Perez, Daniel, additional, Periel, Luis, additional, Perpoint, Thomas, additional, Pesenti, Antonio, additional, Pestre, Vincent, additional, Petrou, Lenka, additional, Petrov-Sanchez, Ventzislava, additional, Pettersen, Frank Olav, additional, Peytavin, Gilles, additional, Pharand, Scott, additional, Piagnerelli, Michael, additional, Picard, Walter, additional, Picone, Olivier, additional, Piero, Maria de, additional, Pierobon, Carola, additional, Piersma, Djura, additional, Pimentel, Carlos, additional, Pinto, Raquel, additional, Pires, Catarina, additional, Pironneau, Isabelle, additional, Piroth, Lionel, additional, Pius, Riinu, additional, Piva, Simone, additional, Plantier, Laurent, additional, Plotkin, Daniel, additional, Png, Hon Shen, additional, Poissy, Julien, additional, Pokeerbux, Ryadh, additional, Pokorska-Spiewak, Maria, additional, Poli, Sergio, additional, Pollakis, Georgios, additional, Ponscarme, Diane, additional, Popielska, Jolanta, additional, Post, Andra-Maris, additional, Postma, Douwe F., additional, Povoa, Pedro, additional, Póvoas, Diana, additional, Powis, Jeff, additional, Prapa, Sofia, additional, Preau, Sébastien, additional, Prebensen, Christian, additional, Preiser, Jean-Charles, additional, Prinssen, Anton, additional, Pritchard, Mark G., additional, Priyadarshani, Gamage Dona Dilanthi, additional, Proença, Lucia, additional, Pudota, Sravya, additional, Puéchal, Oriane, additional, Pujo Semedi, Bambang, additional, Pulicken, Mathew, additional, Puntoni, Matteo, additional, Purcell, Gregory, additional, Quesada, Luisa, additional, Quinones-Cardona, Vilmaris, additional, Quirós González, Víctor, additional, Quist-Paulsen, Else, additional, Quraishi, Mohammed, additional, Rabaa, Maia, additional, Rabaud, Christian, additional, Rabindrarajan, Ebenezer, additional, Rafael, Aldo, additional, Rafiq, Marie, additional, Ragazzo, Gabrielle, additional, Rahman, Ahmad Kashfi Haji Ab, additional, Rahman, Rozanah Abd, additional, Rahutullah, Arsalan, additional, Rainieri, Fernando, additional, Rajahram, Giri Shan, additional, Rajapakse, Nipunie, additional, Ralib, Azrina, additional, Ramakrishnan, Nagarajan, additional, Ramanathan, Kollengode, additional, Ramli, Ahmad Afiq, additional, Rammaert, Blandine, additional, Ramos, Grazielle Viana, additional, Rana, Asim, additional, Rangappa, Rajavardhan, additional, Ranjan, Ritika, additional, Rapp, Christophe, additional, Rashan, Aasiyah, additional, Rashan, Thalha, additional, Rasheed, Ghulam, additional, Rasmin, Menaldi, additional, Rätsep, Indrek, additional, Rau, Cornelius, additional, Ravi, Tharmini, additional, Raza, Ali, additional, Real, Andre, additional, Rebaudet, Stanislas, additional, Redl, Sarah, additional, Reeve, Brenda, additional, Rehan, Ali, additional, Rehman, Attaur, additional, Reid, Liadain, additional, Reikvam, Dag Henrik, additional, Reis, Renato, additional, Rello, Jordi, additional, Remppis, Jonathan, additional, Remy, Martine, additional, Ren, Hongru, additional, Renk, Hanna, additional, Resende, Liliana, additional, Resseguier, Anne-Sophie, additional, Revest, Matthieu, additional, Rewa, Oleksa, additional, Reyes, Luis Felipe, additional, Reyes, Tiago, additional, Ribeiro, Maria Ines, additional, Richardson, David, additional, Richardson, Denise, additional, Richier, Laurent, additional, Ridzuan, Siti Nurul Atikah Ahmad, additional, Riera, Jordi, additional, Rios, Ana L, additional, Rishu, Asgar, additional, Rispal, Patrick, additional, Risso, Karine, additional, Rivera Nuñez, Maria Angelica, additional, Rizer, Nicholas, additional, Robb, Doug, additional, Robba, Chiara, additional, Roberto, André, additional, Roberts, Stephanie, additional, Robertson, David L., additional, Robineau, Olivier, additional, Roche-Campo, Ferran, additional, Rodari, Paola, additional, Rodeia, Simão, additional, Rodriguez Abreu, Julia, additional, Roessler, Bernhard, additional, Roger, Claire, additional, Roger, Pierre-Marie, additional, Roilides, Emmanuel, additional, Rojek, Amanda, additional, Romaru, Juliette, additional, Roncon-Albuquerque Jr, Roberto, additional, Roriz, Mélanie, additional, Rosa-Calatrava, Manuel, additional, Rose, Michael, additional, Rosenberger, Dorothea, additional, Rossanese, Andrea, additional, Rossetti, Matteo, additional, Rossignol, Bénédicte, additional, Rossignol, Patrick, additional, Rousset, Stella, additional, Roy, Carine, additional, Roze, Benoît, additional, Rusmawatiningtyas, Desy, additional, Russell, Clark D., additional, Ryan, Maeve, additional, Ryan, Maria, additional, Ryckaert, Steffi, additional, Rygh Holten, Aleksander, additional, Saba, Isabela, additional, Sadaf, Sairah, additional, Sadat, Musharaf, additional, Sahraei, Valla, additional, Saint-Gilles, Maximilien, additional, Sakiyalak, Pranya, additional, Salahuddin, Nawal, additional, Salazar, Leonardo, additional, Saleem, Jodat, additional, Sales, Gabriele, additional, Sallaberry, Stéphane, additional, Salmon Gandonniere, Charlotte, additional, Salvator, Hélène, additional, Sanchez, Olivier, additional, Sánchez Choez, Xavier, additional, Sanchez de Oliveira, Kizy, additional, Sanchez-Miralles, Angel, additional, Sancho-Shimizu, Vanessa, additional, Sandhu, Gyan, additional, Sandhu, Zulfiqar, additional, Sandrine, Pierre-François, additional, Sandulescu, Oana, additional, Santos, Marlene, additional, Sarfo-Mensah, Shirley, additional, Sarmento Banheiro, Bruno, additional, Sarmiento, Iam Claire E., additional, Sarton, Benjamine, additional, Satyapriya, Sree, additional, Satyawati, Rumaisah, additional, Saviciute, Egle, additional, Savio, Raymond, additional, Savvidou, Parthena, additional, Saw, Yen Tsen, additional, Schaffer, Justin, additional, Schermer, Tjard, additional, Scherpereel, Arnaud, additional, Schneider, Marion, additional, Schroll, Stephan, additional, Schwameis, Michael, additional, Schwartz, Gary, additional, Scott, Janet T., additional, Scott-Brown, James, additional, Sedillot, Nicholas, additional, Seitz, Tamara, additional, Selvanayagam, Jaganathan, additional, Selvarajoo, Mageswari, additional, Semaille, Caroline, additional, Semple, Malcolm G., additional, Senian, Rasidah Bt, additional, Senneville, Eric, additional, Sepulveda, Claudia, additional, Sequeira, Filipa, additional, Sequeira, Tânia, additional, Serpa Neto, Ary, additional, Serrano Balazote, Pablo, additional, Shadowitz, Ellen, additional, Shahidan, Syamin Asyraf, additional, Shahnaz Hasan, Mohd, additional, Shamsah, Mohammad, additional, Shankar, Anuraj, additional, Sharjeel, Shaikh, additional, Sharma, Pratima, additional, Shaw, Catherine A., additional, Shaw, Victoria, additional, Shi, Haixia, additional, Shiban, Nisreen, additional, Shiekh, Mohiuddin, additional, Shiga, Takuya, additional, Shime, Nobuaki, additional, Shimizu, Hiroaki, additional, Shimizu, Keiki, additional, Shimizu, Naoki, additional, Shindo, Nahoko, additional, Shrapnel, Sally, additional, Shum, Hoi Ping, additional, Si Mohammed, Nassima, additional, Siang, Ng Yong, additional, Sibiude, Jeanne, additional, Siddiqui, Atif, additional, Sigfrid, Louise, additional, Sillaots, Piret, additional, Silva, Catarina, additional, Silva, Maria Joao, additional, Silva, Rogério, additional, Sim Lim Heng, Benedict, additional, Sin, Wai Ching, additional, Singh, Budha Charan, additional, Singh, Punam, additional, Sitompul, Pompini Agustina, additional, Sivam, Karisha, additional, Skogen, Vegard, additional, Smith, Sue, additional, Smood, Benjamin, additional, Smyth, Coilin, additional, Smyth, Michelle, additional, Snacken, Morgane, additional, So, Dominic, additional, Soh, Tze Vee, additional, Solis, Monserrat, additional, Solomon, Joshua, additional, Solomon, Tom, additional, Somers, Emily, additional, Sommet, Agnès, additional, Song, Myung Jin, additional, Song, Rima, additional, Song, Tae, additional, Song Chia, Jack, additional, Sonntagbauer, Michael, additional, Soom, Azlan Mat, additional, Sotto, Alberto, additional, Soum, Edouard, additional, Sousa, Ana Chora, additional, Sousa, Marta, additional, Sousa Uva, Maria, additional, Souza-Dantas, Vicente, additional, Sperry, Alexandra, additional, Spinuzza, Elisabetta, additional, Sri Darshana, B. P. Sanka Ruwan, additional, Sriskandan, Shiranee, additional, Stabler, Sarah, additional, Staudinger, Thomas, additional, Stecher, Stephanie-Susanne, additional, Steinsvik, Trude, additional, Stienstra, Ymkje, additional, Stiksrud, Birgitte, additional, Stolz, Eva, additional, Stone, Amy, additional, Streinu-Cercel, Adrian, additional, Streinu-Cercel, Anca, additional, Strudwick, Samantha, additional, Stuart, Ami, additional, Stuart, David, additional, Subekti, Decy, additional, Suen, Gabriel, additional, Suen, Jacky Y., additional, Sukumar, Prasanth, additional, Sultana, Asfia, additional, Summers, Charlotte, additional, Supic, Dubravka, additional, Suppiah, Deepashankari, additional, Surovcová, Magdalena, additional, Suwarti, Suwarti, additional, Svistunov, Andrey A, additional, Syahrin, Sarah, additional, Syrigos, Konstantinos, additional, Sztajnbok, Jaques, additional, Szuldrzynski, Konstanty, additional, Tabrizi, Shirin, additional, Taccone, Fabio S., additional, Tagherset, Lysa, additional, Taib, Shahdattul Mawarni, additional, Talarek, Ewa, additional, Taleb, Sara, additional, Talsma, Jelmer, additional, Tampubolon, Maria Lawrensia, additional, Tan, Kim Keat, additional, Tan, Le Van, additional, Tan, Yan Chyi, additional, Tanaka, Clarice, additional, Tanaka, Hiroyuki, additional, Tanaka, Taku, additional, Taniguchi, Hayato, additional, Tanveer, Hussain, additional, Taqdees, Huda, additional, Taqi, Arshad, additional, Tardivon, Coralie, additional, Tattevin, Pierre, additional, Taufik, M Azhari, additional, Tawfik, Hassan, additional, Tedder, Richard S., additional, Tee, Tze Yuan, additional, Teixeira, João, additional, Tejada, Sofia, additional, Tellier, Marie-Capucine, additional, Teoh, Sze Kye, additional, Teotonio, Vanessa, additional, Téoulé, François, additional, Terpstra, Pleun, additional, Terrier, Olivier, additional, Terzi, Nicolas, additional, Tessier-Grenier, Hubert, additional, Tey, Adrian, additional, Thabit, Alif Adlan Mohd, additional, Tham, Zhang Duan, additional, Thangavelu, Suvintheran, additional, Thibault, Vincent, additional, Thiberville, Simon-Djamel, additional, Thill, Benoît, additional, Thirumanickam, Jananee, additional, Thompson, Shaun, additional, Thomson, David, additional, Thomson, Emma C., additional, Thurai, Surain Raaj Thanga, additional, Thuy, Duong Bich, additional, Thwaites, Ryan S., additional, Tierney, Paul, additional, Tieroshyn, Vadim, additional, Timashev, Peter S, additional, Timsit, Jean-François, additional, Tirupakuzhi Vijayaraghavan, Bharath Kumar, additional, Tissot, Noémie, additional, Toh, Jordan Zhien Yang, additional, Toki, Maria, additional, Tolppa, Timo, additional, Tonby, Kristian, additional, Tonnii, Sia Loong, additional, Torres, Antoni, additional, Torres, Margarida, additional, Torres Santos-Olmo, Rosario Maria, additional, Torres-Zevallos, Hernando, additional, Towers, Michael, additional, Trapani, Tony, additional, Traynor, Damien, additional, Treoux, Théo, additional, Trieu, Huynh Trung, additional, Tripathy, Swagata, additional, Tromeur, Cécile, additional, Trontzas, Ioannis, additional, Trouillon, Tiffany, additional, Truong, Jeanne, additional, Tual, Christelle, additional, Tubiana, Sarah, additional, Tuite, Helen, additional, Turmel, Jean-Marie, additional, Turtle, Lance C.W., additional, Tveita, Anders, additional, Twardowski, Pawel, additional, Uchiyama, Makoto, additional, Udayanga, PG Ishara, additional, Udy, Andrew, additional, Ullrich, Roman, additional, Umer, Zubair, additional, Uribe, Alberto, additional, Usman, Asad, additional, Vajdovics, Cristinava, additional, Val-Flores, Luís, additional, Valle, Ana Luiza, additional, Valran, Amélie, additional, Van de Velde, Stijn, additional, van den Berge, Marcel, additional, van der Feltz, Machteld, additional, van der Valk, Paul, additional, Van Der Vekens, Nicky, additional, Van der Voort, Peter, additional, Van Der Werf, Sylvie, additional, van Dyk, Marlice, additional, van Gulik, Laura, additional, Van Hattem, Jarne, additional, van Lelyveld, Steven, additional, van Netten, Carolien, additional, Van Twillert, Gitte, additional, van Veen, Ilonka, additional, Vanel, Noémie, additional, Vanoverschelde, Henk, additional, Varghese, Pooja, additional, Varrone, Michael, additional, Vasudayan, Shoban Raj, additional, Vauchy, Charline, additional, Vaughan, Helen, additional, Veeran, Shaminee, additional, Veislinger, Aurélie, additional, Vencken, Sebastian, additional, Ventura, Sara, additional, Verbon, Annelies, additional, Vidal, José Ernesto, additional, Vieira, César, additional, Vijayan, Deepak, additional, Villanueva, Joy Ann, additional, Villar, Judit, additional, Villeneuve, Pierre-Marc, additional, Villoldo, Andrea, additional, Vinh Chau, Nguyen Van, additional, Visseaux, Benoit, additional, Visser, Hannah, additional, Vitiello, Chiara, additional, Vonkeman, Harald, additional, Vuotto, Fanny, additional, Wahab, Noor Hidayu, additional, Wahab, Suhaila Abdul, additional, Wahid, Nadirah Abdul, additional, Wainstein, Marina, additional, Wan Muhd Shukeri, Wan Fadzlina, additional, Wang, Chih-Hsien, additional, Webb, Steven Anthony, additional, Wei, Jia, additional, Weil, Katharina, additional, Wen, Tan Pei, additional, Wesselius, Sanne, additional, West, T. Eoin, additional, Wham, Murray, additional, Whelan, Bryan, additional, White, Nicole, additional, Wicky, Paul Henri, additional, Wiedemann, Aurélie, additional, Wijaya, Surya Otto, additional, Wille, Keith, additional, Willems, Suzette, additional, Williams, Virginie, additional, Wils, Evert-Jan, additional, Wing Yiu, Ng, additional, Wong, Calvin, additional, Wong, Teck Fung, additional, Wong, Xin Ci, additional, Wong, Yew Sing, additional, Xian, Gan Ee, additional, Xian, Lim Saio, additional, Xuan, Kuan Pei, additional, Xynogalas, Ioannis, additional, Yacoub, Sophie, additional, Yakop, Siti Rohani Binti Mohd, additional, Yamazaki, Masaki, additional, Yazdanpanah, Yazdan, additional, Yee Liang Hing, Nicholas, additional, Yelnik, Cécile, additional, Yeoh, Chian Hui, additional, Yerkovich, Stephanie, additional, Yokoyama, Toshiki, additional, Yonis, Hodane, additional, Yousif, Obada, additional, Yuliarto, Saptadi, additional, Zaaqoq, Akram, additional, Zabbe, Marion, additional, Zacharowski, Kai, additional, Zahid, Masliza, additional, Zahran, Maram, additional, Zaidan, Nor Zaila Binti, additional, Zambon, Maria, additional, Zambrano, Miguel, additional, Zanella, Alberto, additional, Zawadka, Konrad, additional, Zaynah, Nurul, additional, Zayyad, Hiba, additional, Zoufaly, Alexander, additional, and Zucman, David, additional

Published
2021
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27. Deficiency of intramuscular ICC increases fundic muscle excitability but does not impede nitrergic innervation

Author

Huizinga, Jan D., Liu, Louis W.C., Fitzpatrick, Amanda, White, Elizabeth, Gill, Sandeep, Wang, Xuan-Yu, Zarate, Natalia, Krebs, Lynn, Choi, Catherine, Starret, Tanya, Dixit, Devika, and Ye, Jing

Subjects
Muscle cells -- Health aspects, Muscle cells -- Research, Muscle contraction -- Health aspects, Muscle contraction -- Research, Biological sciences
Abstract

The motility of the gastrointestinal tract is generated by smooth muscle cells and is controlled to a large extent by an intrinsic neural network. A gap of ~200 nm usually separates nerve varicosities from smooth muscle cells, which suggests that direct innervation of the smooth muscle by synapses does not occur. Enteric nerves do make synapse-like contact with proposed regulatory cells, the interstitial cells of Cajal (ICC), which in turn may be in gap junction contact with smooth muscle cells. The role played by ICC in enteric innervation is controversial. Experimental evidence has been presented in vitro for the hypothesis that nitrergic inhibitory innervation is strongly reduced in the absence of ICC. However, in vivo data appear to dispute that. The present report provides evidence that explains the discrepancy between in vivo and in vitro data and provides evidence that inhibitory neurotransmitters can reach smooth muscle cells without hindrance when ICC are absent. The fundic musculature shows increased responses to substance P-mediated innervation and shows marked spontaneous activity, which is consistent with increased muscle excitability. interstitial cells of Cajal

Published
2008

28. Interstitial cells of Cajal and adaptive relaxation in the mouse stomach

Author

Dixit, Devika, Zarate, Natalia, Liu, Louis W.C., Boreham, Douglas R., and Huizinga, Jan D.

Subjects
Luteinizing hormone -- Research, Intestine, Small -- Research, Nervous system, Autonomic -- Research, Biological sciences
Abstract

Interstitial cells of Cajal (ICC) are proposed to play a role in stretch activation of nerves and are under intense investigation for potential roles in enteric innervation. Most data to support such roles come from in vitro studies with muscle strips whereas data at the whole organ level are scarce. To obtain insight into the role of ICC in distention-induced motor patterns developing at the organ level, we studied distension-induced adaptive relaxation in the isolated whole stomach of wild-type and W/[W.sup.v] mice. A method was developed to assess gastric adaptive relaxation that gave quantitative information on rates of pressure development and maximal adaptive relaxation. Pressure development was monitored throughout infusion of l ml of solution over a 10-min period. The final intraluminal pressure was sensitive to blockade of nitric oxide synthase, in wild-type and W/[W.sup.v] mice to a similar extent, indicating NO-mediated relaxation in W/[W.sup.v] mice. Adaptive relaxation occurred between 0.2 and 0.5 ml of solution infusion; this reflex was abolished by TTX, was not sensitive to blockade of nitric oxide synthase, but was abolished by apamin, suggesting that ATP and not nitric oxide is the neurotransmitter responsible for this intrinsic reflex. Despite the absence of intramuscular ICC (ICC-IM), normal gastric adaptive relaxation occurred in the W/[W.sup.v] stomach. Because pressure development was significantly lower in W/[W.sup.v]mice compared with wild type in all the conditions studied, including in the presence of TTX, ICC-IM may play a role in development of myogenic tone. In conclusion, a mouse model was developed to assess the intrinsic component of gastric accommodation. This showed that ICC-IM are not essential for activation of intrinsic sensory nerves nor ATP-driven adaptive relaxation nor NO-mediated relaxation in the present model. ICC-IM may be involved in regulation of (distention-induced) myogenic tone. gastric motility; enteric nerves; enteric sensory nerves; inhibitory enteric neurotransmission; gastric accommodation

Published
2006

31. Asymptomatic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in adults is uncommon using rigorous symptom characterization and follow-up in an acute-care adult hospital outbreak

Author

O’Grady, Heidi M., Dixit, Devika, Khawaja, Zoha, Snedeker, Kate, Ellison, Jennifer, Erebor, Joyce, Jamieson, Peter, Weiss, Amanda, Salcedo, Daniel, Roberts, Kimberley, Wiens, Karen, Etches, Nicholas, Leal, Jenine, and Conly, John M.

Abstract

AbstractAsymptomatic coronavirus disease 2019 (COVID-19) has been reported as a significant driver of COVID-19 outbreaks. Our hospital ward outbreak analysis suggests that comprehensive symptoms and signs assessment, in combination with adequate follow-up, allows a more precise determination of COVID-19 symptoms. Asymptomatic infection was quite uncommon among adults in this setting.

Published
2023
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35. New WHO guidelines on the management of pregnancy and breastfeeding in the context of Ebola

Author

Thorson, Anna E, primary, Foeller, Megan E, additional, Caluwaerts, Severine, additional, Ribeiro do Valle, Carolina, additional, Crozier, Ian, additional, Deen, Gibrilla, additional, Dixit, Devika, additional, Godwin, Chrissy, additional, Okong, Pius, additional, Esteves Soeiro, Rachel, additional, Sousa, João Paulo, additional, van Herp, Michel, additional, Bucagu, Maurice, additional, Costa, Alejandro, additional, Foeller, Megan, additional, Formenty, Pierre, additional, Gill, Roopan, additional, Kim, Caron, additional, Kini, Brigitte, additional, Legand, Anais, additional, Oladapo, Olufemi, additional, Ouedraogo, Leopold, additional, Perkins, Mark, additional, Thorson, Anne, additional, and Titulaer, Patricia, additional

Published
2020
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38. Review of Ebola virus disease in children – how far have we come?

Author

Dixit, Devika, Masumbuko Claude, Kasereka, Kjaldgaard, Lindsey, and Hawkes, Michael T.

Subjects
*EBOLA virus disease, *COVID-19, *EBOLA virus, *ADULT respiratory distress syndrome, *HEMORRHAGIC fever
Abstract

Ebola virus (EBOV) causes an extremely contagious viral haemorrhagic fever associated with high mortality. While, historically, children have represented a small number of total cases of Ebolavirus disease (EVD), in recent outbreaks up to a quarter of cases have been in children. They pose unique challenges in clinical management and infection prevention and control. In this review of paediatric EVD, the epidemiology of past EVD outbreaks with specific focus on children is discussed, the clinical manifestations and laboratory findings are described and key developments in clinical management including specific topics such as viral persistence and breastfeeding while considering unique psychosocial and anthropological considerations for paediatric care including of survivors and orphans and the stigma they face are discussed. In addition to summarising the literature, perspectives based on the authors' experience of EVD outbreaks in the Democratic Republic of the Congo (DRC) are described. Abbreviations: ARDS: acute respiratory distress syndrome; aOR: adjusted odds ratio; ALT: alanine transferase; ALIMA: Alliance for International Medical Action; AST: aspartate transaminase; BUN: blood urea nitrogen; CNS: central nervous system; CUBE: chambre d'urgence biosécurisée pour épidémie; COVID-19: coronavirus disease 2019; Ct: cycle threshold; DRC: Democratic Republic of Congo; ETC: ebola treatment centre; ETU: ebola treatment unit; EBOV: ebola virus; EVD: ebolavirus disease; FEAST: fluid expansion as supportive therapy; GP: glycoprotein; IV: intravenous; MEURI: monitored emergency use of unregistered interventions; NETEC: National Ebola Training and Education Centre; NP: nucleoprotein; ORS: oral rehydration solution; PALM: Pamoja Tulinde Maisha; PREVAIL: Partnership for Research on Ebola Virus in Liberia; PPE: personal protective equipment; PCR: polymerase chain reaction; PEP: post-exposure prophylaxis; RDTs: rapid diagnostic tests; RT: reverse transcriptase; RNA: ribonucleic acid; UNICEF: United Nations International Children's Emergency Fund; USA: United States of America; WHO: World Health Organization [ABSTRACT FROM AUTHOR]

Published
2021
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39. Human and novel coronavirus infections in children: a review.

Author

Rajapakse, Nipunie and Dixit, Devika

Subjects
*SARS-CoV-2, *COVID-19, *RESPIRATORY infections, *SARS disease, *MERS coronavirus
Abstract

Coronaviruses, seven of which are known to infect humans, can cause a spectrum of clinical presentations ranging from asymptomatic infection to severe illness and death. Four human coronaviruses (hCoVs)—229E, HKU1, NL63 and OC43—circulate globally, commonly infect children and typically cause mild upper respiratory tract infections. Three novel coronaviruses of zoonotic origin have emerged during the past two decades: severe acute respiratory syndrome coronavirus (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV) and the recently discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is the cause of the ongoing coronavirus disease 2019 (COVID-19) pandemic. These novel coronaviruses are known to cause severe illness and death predominantly in older adults and those with underlying comorbidities. Consistent with what has been observed during the outbreaks of SARS and MERS, children with COVID-19 are more likely to be asymptomatic or to have mild-to-moderate illness, with few deaths reported in children globally thus far. Clinical symptoms and laboratory and radiological abnormalities in children have been similar to those reported in adults but are generally less severe. A rare multisystem inflammatory syndrome in children (MIS-C) which has resulted in critical illness and some deaths has recently been described. Clinical trials for therapeutics and vaccine development should include paediatric considerations. Children may play an important role in the transmission of infection and outbreak dynamics and could be a key target population for effective measures to control outbreaks. The unintended consequences of the unprecedented scale and duration of pandemic control measures for children and families around the world should be carefully examined. Abbreviations: 2019-nCoV, 2019 novel coronavirus; ADEM, acute demyelinating encephalomyelitis; AAP, American Academy of Pediatrics; ACE-2, angiotensin-converting enzyme 2; ARDS, acute respiratory distress syndrome; BCG, bacillus Calmette–Guérin; BNP, brain natriuretic peptide; CDC, Centers for Disease Control and Prevention; CRP, C-reactive protein; CSF, cerebrospinal fluid; COVID-19, coronavirus disease 2019; CT, computed tomography; CXR, chest X-ray; DOL, day of life; hCoV, human coronavirus; ICU, intensive care unit; IL, interleukin; IVIG, intravenous immunoglobulin; KD, Kawasaki disease; LDH, lactate dehydrogenase; MERS, Middle East respiratory syndrome; MERS-CoV, Middle East respiratory syndrome coronavirus; MEURI, monitored emergency use of unregistered and experimental interventions; MIS-C, multi-system inflammatory syndrome in children; PCR, polymerase chain reaction; PICU, paediatric intensive care unit; RNA, ribonucleic acid; RCT, randomised-controlled trial; RSV, respiratory syncytial virus; SARS, severe acute respiratory syndrome; SARS-CoV-1, severe acute respiratory syndrome coronavirus 1; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TNF-alpha, tumour necrosis factor alpha; UK United Kingdom; UNICEF, United Nations Children's Fund; USA, United States of America; WHO, World Health Organization [ABSTRACT FROM AUTHOR]

Published
2021
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40. New WHO guidelines on the management of pregnancy and breastfeeding in the context of Ebola

Author

Caluwaerts, Severine, Ribeiro do Valle, Carolina, Crozier, Ian, Deen, Gibrilla, Dixit, Devika, Godwin, Chrissy, Okong, Pius, Esteves Soeiro, Rachel, Sousa, João Paulo, van Herp, Michel, Bucagu, Maurice, Costa, Alejandro, Foeller, Megan, Formenty, Pierre, Gill, Roopan, Kim, Caron, Kini, Brigitte, Legand, Anais, Oladapo, Olufemi, Ouedraogo, Leopold, Perkins, Mark, Thorson, Anne, Titulaer, Patricia, Thorson, Anna E, and Foeller, Megan E

Published
2020
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42. Nodular Lung Lesions in a 10-Week-Old Infant

Author

Shah, Gauri, primary, Tse-Chang, Alena, additional, Cooper, Ryan, additional, Robinson, Joan, additional, Zorzela, Liliane, additional, Amirav, Israel, additional, Codesal, Maria Castro, additional, Dixit, Devika, additional, Hansen, Elisabeth, additional, and Hawkes, Michael, additional

Published
2015
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45. A Case Report of Multiple Cerebral Abscesses Due to Nocardiain the Absence of Pulmonary Disease

Author

Elliott, Mark and Dixit, Devika

Abstract

Central nervous system (CNS) Nocardial infections carry a significantly higher mortality than other causative organisms. They are recalcitrant infections requiring long treatment courses with double, or even triple, antibiotic coverage. This case report fills a gap in the recent literature regarding CNS Nocardiosis because the authors were unable to culture the organism necessitating empiric therapy for an extended duration, its atypical staining pattern, and absence of pulmonary disease, which is uncommon.A 64-year-old woman with Waldenström macroglobulinemia presented with seizures and was found to have multifocal Nocardia farcinicacerebral abscesses. Nocardiaspecies are an uncommon cause of cerebral abscesses that can occur spontaneously via inoculation from the environment, especially in immunocompromised patients, and usually appear with concomitant pulmonary disease. Nocardiainfections generally portend a worse prognosis than other organisms causing the same clinical syndrome because they are difficult to treat. Treatment of cerebral Nocardiaconsists of combination therapy upfront with a sulfonamide and another agent, with long treatment regimens of up to a year.

Published
2018
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46. Mucosal Healing Among Black and White Patients With Inflammatory Bowel Disease.

Author

Dixit D, Ruiz NC, Shen S, Daneshmand A, Rodriguez VI, Qian S, Neal D, Rampertab SD, Zimmermann EM, and Kamel AY

Subjects
Adult, Female, Humans, Male, Middle Aged, Young Adult, Black or African American, C-Reactive Protein analysis, Colitis, Ulcerative ethnology, Colitis, Ulcerative therapy, Crohn Disease ethnology, Crohn Disease therapy, Intestinal Mucosa pathology, Retrospective Studies, Wound Healing, White, Hospitalization statistics & numerical data, Inflammatory Bowel Diseases ethnology, Inflammatory Bowel Diseases therapy
Abstract

Introduction: Crohn's disease and ulcerative colitis are characterized by chronic inflammation of the gastrointestinal tract. Mucosal healing (MH) is a therapeutic goal in patients with inflammatory bowel disease (IBD). Current data suggest that Black patients may experience worse clinical outcomes than White patients with IBD. This study assessed MH between Black and White patients with IBD., Methods: Retrospective analysis was performed on Black and White adults with IBD who were hospitalized for an active flare. The presence of MH was assessed at 6-18 months after hospitalization. IBD treatments received before and during hospitalization, within 6 months, and 6-18 months after discharge were recorded. C-reactive protein (CRP) levels were collected at hospitalization and 6-18 months after discharge; the difference was reported as delta CRP., Results: One hundred nine patients were followed up after hospitalization. Of those 88 (80.7%) were White patients, and 21 (19.3%) were Black patients. White and Black patients received similar proportions of IBD treatment before ( P = 0.2) and during ( P = 0.6) hospitalization, within 6 months ( P = 0.1), and 6-18 months ( P = 0.1) after discharge. Black patients achieved numerically higher rates of MH (15/21 = 71.4% vs 53/88 = 60.2%, P = 0.3) and delta CRP ( P = 0.2) than White patients, however, not statistically significant., Discussion: In patients admitted to the hospital with an IBD flare with similar treatment and care, there was a trend toward higher rates of MH in Black patients compared with White patients. These data suggest that MH is likely not the only factor that is associated with Black patients experiencing worse clinical outcomes when compared with White patients., (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)

Published
2024
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47. Summary of WHO infection prevention and control guideline for Ebola and Marburg disease: a call for evidence based practice.

Author

Willet V, Dixit D, Fisher D, Bausch DG, Ogunsola F, Khabsa J, Akl EA, and Baller A

Subjects
Animals, Humans, Evidence-Based Practice, World Health Organization, Hemorrhagic Fever, Ebola epidemiology, Hemorrhagic Fever, Ebola prevention & control, Marburg Virus Disease prevention & control, Ebolavirus
Abstract

Competing Interests: Competing interests: All members of the guideline development group completed declaration of interest forms, none of which identified any member who had a conflict.

Published
2024
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48. Asymptomatic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in adults is uncommon using rigorous symptom characterization and follow-up in an acute-care adult hospital outbreak.

Author

O'Grady HM, Dixit D, Khawaja Z, Snedeker K, Ellison J, Erebor J, Jamieson P, Weiss A, Salcedo D, Roberts K, Wiens K, Etches N, Leal J, and Conly JM

Subjects
Adult, Humans, Follow-Up Studies, Disease Outbreaks, Hospitals, SARS-CoV-2, COVID-19 diagnosis
Abstract

Asymptomatic coronavirus disease 2019 (COVID-19) has been reported as a significant driver of COVID-19 outbreaks. Our hospital ward outbreak analysis suggests that comprehensive symptoms and signs assessment, in combination with adequate follow-up, allows a more precise determination of COVID-19 symptoms. Asymptomatic infection was quite uncommon among adults in this setting.

Published
2023
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