300 results on '"Diurnal enuresis"'
Search Results
2. Think Dry: Optimalisation of Diagnostic Process of Urinary Incontinence in Older People
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- 2024
3. Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
- Author
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Aarhus University Hospital, Regional Hospital West Jutland, North Denmark Regional Hospital, and Kristina Thorsteinsson, Principal Investigator
- Published
- 2023
4. Biofeedback and Osteopathic Procedures for Daytime Urinary Incontinence (BOFDUI)
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Hany Mohamed Ibrahim Elgohary, associate professor
- Published
- 2023
5. Voiding School as a Treatment of Children's Day-time Incontinence or Enuresis
- Author
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University of Turku, Southern Health and Social Care Trust, and Anneli Saarikoski, MNSc, RN
- Published
- 2021
6. 家族聚集性遗尿儿童临床特征及情绪 与行为异常的相关因素分析.
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刘亚凯, 司峰, 王颂扬, 贾茹, 左佳, 李庆斌, 范毛川, 杨静, and 文建国
- Abstract
Objective To explore the clinical characteristics and related factors of emotional and behav-ioral abnormality in children with family primary nocturnal enuresis( FPNE). Methods From September 2021 to September 2022, clinical data were collected from 306 children with primary nocturnal enuresis at our enure-sis clinic. General information questionnaire, strengths and difficulties questionnaire and Pediatric Sleep Ques-tionnaire ( PSQ). Children with PNE were divided into family primary nocturnal enuresis group ( FPNE group, n =45 ) and sporadic primary nocturnal enuresis group ( SPNE group, n = 261 ) according to whether family mem-bers of the third generation were involved. The clinical characteristics, emotional and behavioral changes of FPNE group were analyzed. Results The incidences of severe NE, non-monosymptomatic nocturnal enuresis ( NMNE), abnormal stool and nocturnal micturition twice in FPNE group were(68%, 75%, 48% and 42% respectively) significantly higher than sporadic enuresis group ( SPNE group) ( 57%, 47%, 24% and 11 % re-spectively). The difference was statistically significant( P < 0. 05 ) . The number of enuresis children aged 13 —16 years was 44. 4% ( 20/45) in FPNE group and it was significantly higher than 19. 2% ( 50/261) in SPNE group. The difference was statistically significant( P < 0. 05 ). In FPNE group, 46. 7% (21/45 ) children were au-tosomal dominant, 33. 3% ( 15/45 ) children were autosomal stealth inheritance and 20. 0% ( 9/45) children showed polygenic inheritance. The total scores of emotional symptoms, hyperactivity symptoms and difficulties in FPNE group were higher than those in SPNE group. The difference is statistically significant (P <0. 05 ) . No sig-nificant inter-group difference existed in scores of conduct problems, peer communication or society ( P > 0. 05 ). Logistic regression analysis indicated that age, poor academic performance and high total score of PSQ were the influencing factors of emotional symptoms in FPNE group. Poor academic performance, abnormal stool, bladder dysfunction and high total score of PSQ were the influencing factors of hyperactivity symptoms in FPNE children. Conclusion There are many ways of inheritance of FPNE, among which autosomal dominant inheritance is the most common, the incidence of emotional symptoms and hyperactive symptoms is high, and clinical symptoms are more serious, the risk of frequent and urgent urination is higher, and it is not easy to cure with age. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Persistent diurnal enuresis in a 6-year-old boy after bilateral ureteroneocystostomy
- Author
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Tomasz Szawłoga, Aleksandra Orzechowska, and Aleksandra Sobieszczańska-Droździel
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diurnal enuresis ,hydronephrosis ,vesicoureteral reflux ,posterior urethral valves ,Education ,Sports ,GV557-1198.995 ,Medicine - Abstract
Urinary incontinence is one of the most common symptoms in children and adolescents. Due to numerous causes, a thorough examination is necessary. We present a case of a 6-year-old boy with diurnal enuresis, who was admitted to our Department for further treatment after the procedure of bilateral ureteroneocystostomy due to suspected bilateral ureter stenosis. With the persistence of the incontinence, our examination revealed a posterior urethral valve which was incised and the symptoms subsided.
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- 2023
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8. Mebeverine For 1st Year Daytime And Nocturnal Incontinence After Orthotopic W-Ileal Neobladders
- Author
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Abdelwahab Hashem, Urology Msc, Oncology fellow at Urology and Nephrology Center, Principal Investigator
- Published
- 2020
9. Diuretic Effect Evaluation of Petroselinum Crispum (Parsley) in Hypertensive Patients (DEEP)
- Author
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Imam Abdulrahman Bin Faisal University and Atta Abbas Naqvi, Prinicipal Investigator
- Published
- 2020
10. Early Behavioral Risks of Childhood and Adolescent Daytime Urinary Incontinence and Nocturnal Enuresis
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Vasconcelos, Monica MA, East, Patricia, Blanco, Estela, Lukacz, Emily S, Caballero, Gabriela, Lozoff, Betsy, and Gahagan, Sheila
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Paediatrics ,Biomedical and Clinical Sciences ,Pediatric ,Urologic Diseases ,Prevention ,Adolescent ,Child ,Child Behavior Disorders ,Chile ,Diurnal Enuresis ,Female ,Humans ,Longitudinal Studies ,Male ,Nocturnal Enuresis ,Risk Factors ,Temperament ,urinary incontinence ,nocturnal enuresis ,urinary control ,infant temperament ,internalizing symptoms ,externalizing behaviors ,childhood inattention ,longitudinal ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Developmental & Child Psychology ,Biomedical and clinical sciences ,Health sciences ,Psychology - Abstract
ObjectiveTo investigate whether infant temperament and childhood internalizing, externalizing, and inattention symptoms increase the likelihood of daytime urinary incontinence or nocturnal enuresis at 10 years and adolescence (11.9-17.8 years).MethodData were from a longitudinal cohort of 1119 healthy Chilean children. We assessed behavioral symptoms at infancy, 5 years, and 10 years and their relationship with subsequent daytime urinary incontinence and nocturnal enuresis.ResultsDaytime urinary incontinence and nocturnal enuresis occurred in, respectively, 3.3% and 11.4% at 10 years and 1.1% and 2.7% at adolescence. Difficult infant temperament was associated with increased odds of 10-year daytime urinary incontinence. Inattention at 5 years was associated with increased odds for nocturnal enuresis at 10 years and adolescence. Internalizing and externalizing symptoms at 5 years were associated with increased odds of 10-year daytime urinary incontinence and nocturnal enuresis. Internalizing and externalizing symptoms at 10 years were associated with adolescent nocturnal enuresis.ConclusionTemperament and internal/externalizing symptoms may be risk factors for school-age and adolescent urinary incontinence.
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- 2017
11. Exploring the Genetic Risk of Childhood Daytime Urinary Incontinence: A Genome-Wide Association Study.
- Author
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Breinbjerg A, Jørgensen CS, Walters GB, Grove J, Als TD, Kamperis K, Stéfansdóttir L, Thirstrup JP, Borg B, Albiñana C, Vilhjálmsson BJ, Eðvarðsson VÖ, Stefánsson H, Mortensen PB, Agerbo E, Werge T, Børglum A, Demontis D, Stefánsson K, Rittig S, and Christensen JH
- Abstract
Purpose: Childhood incontinence is stigmatized and underprioritized, and a basic understanding of its pathogenesis is missing. Our goal was to identify risk-conferring genetic variants in daytime urinary incontinence (DUI)., Materials and Methods: We conducted a genome-wide association study in the Danish iPSYCH2015 cohort. Cases (3024) were identified through DUI diagnosis codes and redeemed prescriptions for DUI medication in patients aged 5 to 20 years. Controls (30,240), selected from the same sample, were matched to cases on sex and psychiatric diagnoses, if any, and down-sampled to a 1:10 case:control ratio. Replication was performed in the Icelandic deCODE cohort (5475 cases/287,773 controls). Single-nucleotide polymorphism heritability was calculated using the genome-based restricted maximum likelihood method. Cross-trait genetic correlation was estimated using linkage disequilibrium score regression. Polygenic risk scores generated with LDpred2-auto and BOLT-LMM were assessed for association., Results: Variants on chromosome 6 (rs12210989, odds ratio [OR] 1.24, 95% CI 1.17-1.32, P = 3.21 × 10
-12 ) and 20 (rs4809801, OR 1.18, 95% CI 1.11-1.25, P = 3.66 × 10-8 ) reached genome-wide significance and implicated the PRDM13 and RIPOR3 genes. Chromosome 6 findings were replicated ( P = .024, OR 1.09, 95% CI 1.01-1.16). Liability scale heritability ranged from 10.20% (95% CI 6.40%-14.00%) to 15.30% (95% CI 9.66%-20.94%). DUI and nocturnal enuresis showed positive genetic correlation ( rg = 1.28 ± 0.38, P = .0007). DUI was associated with attention-deficit/hyperactivity disorder (OR 1.098, 95% CI 1.046-1.152, P < .0001) and BMI (OR 1.129, 95% CI 1.081-1.178, P < .0001) polygenic risk., Conclusions: Common genetic variants contribute to the risk of childhood DUI, and genes important in neuronal development and detrusor smooth muscle activity were implicated. These findings may help guide identification of new treatment targets.- Published
- 2024
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12. Urotherapy vs. Urotherapy With Constipation Treatment for Children With Lower Urinary Tract Dysfunction
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Noam Zevit, Pediatric Gastroenterologist
- Published
- 2018
13. Urinary incontinence during laughter in children: Is it giggle incontinence?
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San, Soe T, Barnes, Elizabeth H, and Caldwell, Patrina H Y
- Subjects
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URINARY incontinence , *LAUGHTER , *URINARY organs , *URINALYSIS , *GENDER , *SYMPTOMS - Abstract
Aim: Giggle incontinence is a distinct entity of childhood daytime urinary incontinence (DUI), where children wet themselves only when they laugh. The prevalence of true giggle incontinence is unknown, with confusion about the diagnosis of urinary incontinence occurring during laughter and true giggle incontinence. The aim of the study is to improve our understanding of urinary incontinence during laughter by comparing those children with children who have DUI at other times, but not with laughter. Methods: We conducted a retrospective medical record review of children with DUI who presented to a tertiary continence service from 2017 to 2018, collecting data on age, gender, associated comorbidities, lower urinary tract symptoms, investigations, provisional diagnosis at first visit and initial treatment responses. Differences between those with DUI occurring during laughter and those with DUI at other times, but not with laughter were compared using standard statistical methods. Results: Of the 277 new patients seen during the study period, 140 (51%) had DUI, and of these, 72 (51%) had DUI occurring during laughter. Children with incontinence occurring during laughter were more likely to have incontinence associated with other activities. One child had giggle incontinence according to the International Children's Continence Society's definition. Four other children were referred specifically for urinary incontinence associated with laughter, with the term giggle incontinence sometimes used by the referring doctor. Conclusion: Children with DUI commonly experience incontinence during laughter, but true giggle incontinence is rare. Correct diagnosis is essential as it directs treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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14. Micturition Reeducation in Children With Cerebral Palsy
- Published
- 2017
15. Elimination Disorders
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Law, Stu, Malady, Mark, Buqo, Tom, Williams, Larry, Maragakis, Alexandros, editor, and O'Donohue, William T., editor
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- 2018
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16. Diurnal Enuresis Secondary to Aripiprazole in A Child With Autistic Disorder: A Case Report
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Öznur Bilaç, Akın Tahıllıoğlu, Aylin Deniz Uzun, and Arif Önder
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autism ,diurnal enuresis ,aripiprazole ,child psychiatry ,antipsychotic ,Pediatrics ,RJ1-570 - Published
- 2021
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17. Anxiety disorders, depression and incontinence in preschool children—A population‐based study
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Justine Hussong, Marion Greiner, Ulrike Schiedermaier, Hannah Mattheus, and Alexander von Gontard
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Male ,Depression ,Child, Preschool ,Surveys and Questionnaires ,Urology ,Humans ,Female ,Neurology (clinical) ,Diurnal Enuresis ,Constipation ,Anxiety Disorders ,Fecal Incontinence ,Nocturnal Enuresis - Abstract
The aim was to examine associations of specific anxiety disorders, depressive symptoms, and incontinence in a representative, population-based sample of preschool children.All preschool children of a defined geographical area examined before school-entry were included. Parents completed a questionnaire including the Preschool Feelings Checklist (PFC), eight questions referring to nocturnal enuresis (NE), daytime urinary incontinence (DUI), fecal incontinence (FI) and constipation, and 30 items regarding Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) diagnostic criteria of separation anxiety disorder (SAD), social phobia (SOC), specific phobia (PHOB), and generalized anxiety disorder (GAD). Data of 1206 children (mean age = 5.7 years; 53.5% boys) are presented.34.6% of incontinent children had an anxiety disorder based on DSM-5 criteria and 13.3% had clinically relevant depressive symptoms (measured by the PFC). Rates of incontinence overall were 14.1% (11.9% NE, 3.1% DUI, and 1.8% FI) and 6.3% for constipation. Rates of SOC and PHOB were increased in NE (20.8% and 25.4%), DUI (39.3% and 34.5%) and FI (35.3% and 50.0%) compared to continent children (13.5% and 17.2%). Children with constipation had higher rates of SOC, PHOB, and GAD than those without. Compared to continent children (9.7%), depressive symptoms were more frequent in children with NE (26.8%), DUI (50.0%), and FI (61.9%).Anxiety disorders and depressive symptoms are common in children with incontinence. The most specific DSM-5 disorders associated with incontinence are SOC and PHOB, which can be incapacitating and may require treatment. Due to the high rates of anxiety disorders, it is important to screen all children with incontinence, for example, with specific questionnaires.
- Published
- 2022
18. Diurnal enuresis developing in association with risperidone and aripiprazole use in a child with autism spectrum disorder: a case report
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Hamza Ayaydın and Şermin Bilgen Ulgar
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Autism ,diurnal enuresis ,aripiprazole ,risperidone ,child ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder. Risperidone and Aripiprazole appear to be effective in associated behavioural problems with ASDs, including irritability, aggressiveness, hyperactivity, self-injurious behaviour, and stereotypies. In our case, new-onset diurnal enuresis was observed as a side effect after risperidone use. New-onset diurnal enuresis improved when risperidone was stopped, but recommenced when aripiprazole was added to treatment. However, all symptoms of enuresis resolved when the aripiprazole dosage was reduced. In contrast to some reports in which aripiprazole was used in the treatment of enuresis, our case is different in that it led to diurnal enuresis.
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- 2018
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19. Managing children with daytime urinary incontinence: a survey of Dutch general practitioners.
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Oldenhof AP, Linde JM, Hofmeester I, Steffens MG, Kloosterman-Eijgenraam FJ, and Blanker MH
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- Humans, Child, Family Practice, Surveys and Questionnaires, Life Style, Referral and Consultation, General Practitioners, Diurnal Enuresis
- Abstract
Background: In the Netherlands, parents of children with daytime urinary incontinence (UI) first consult general practitioners (GPs). However, GPs need more specific guidelines for daytime UI management, resulting in care and referral decisions being made without clear guidance., Objectives: We aimed to identify Dutch GP considerations when treating and referring a child with daytime UI., Methods: We invited GPs who referred at least one child aged 4-18 years with daytime UI to secondary care. They were asked to complete a questionnaire about the referred child and the management of daytime UI in general., Results: Of 244 distributed questionnaires, 118 (48.4%) were returned by 94 GPs. Most reported taking a history and performing basic diagnostic tests like urine tests (61.0%) and physical examinations (49.2%) before referral. Treatment mostly involved lifestyle advice, with only 17.8% starting medication. Referrals were usually at the explicit wish of the child/parent (44.9%) or because of symptom persistence despite treatment (39.0%). GPs usually referred children to a paediatrician ( n = 99, 83.9%), only referring to a urologist in specific situations. Almost half (41.4%) of the GPs did not feel competent to treat children with daytime UI and more than half (55.7%) wanted a clinical practice guideline. In the discussion, we explore the generalisability of our findings to other countries., Conclusion: GPs usually refer children with daytime UI to a paediatrician after a basic diagnostic assessment, usually without offering treatment. Parental or child demand is the primary stimulus for referral.
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- 2023
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20. Continence Problems and Mental Health in Adolescents from a UK Cohort.
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Gordon K, Warne N, Heron J, von Gontard A, and Joinson C
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- Male, Child, Female, Humans, Adolescent, Mental Health, Prospective Studies, United Kingdom epidemiology, Diurnal Enuresis, Urinary Incontinence diagnosis, Lower Urinary Tract Symptoms
- Abstract
Background: Adolescents with continence problems experience unique threats to their psychological well-being, but long-term mental health sequelae are unknown., Objective: To examine prospective relationships between incontinence/lower urinary tract symptoms (LUTS) and mental health problems in young people., Design, Setting, and Participants: A prospective cohort study of young people (n = 7332: 3639 males and 3693 females) from a population-based sample was conducted., Outcome Measurements and Statistical Analysis: We estimated the association between incontinence/LUTS and mental health outcomes using multivariable regression models adjusted for sex, socioeconomic position, developmental level, intelligence quotient, stressful life events, maternal psychopathology, body mass index, and emotional/behavioural problems., Results and Limitations: Daytime wetting and voiding postponement showed the greatest number of associations with mental health problems. All incontinence subtypes/LUTS were associated with increased odds of generalised anxiety disorder (eg, odds ratio for daytime wetting = 3.01, 95% confidence interval [1.78, 5.09], p < 0.001) and/or higher anxiety scores. There was also evidence of associations with common mental disorder (eg, voiding postponement: 1.88 [1.46, 2.41], p < 0.001), depression (eg, urgency: 1.94 [1.19, 3.14], p = 0.008), depressive symptoms (eg, daytime wetting: 1.70 [1.13, 2.56], p = 0.01), self-harm thoughts (eg, voiding postponement: 1.52 [1.16, 1.99], p = 0.003), and disordered eating (eg, nocturia 1.72 [1.27, 2.34], p = 0.001). We are unable to generalise our results to minority ethnic groups, less affluent populations, and non-UK samples., Conclusions: Young people with incontinence/LUTS are at an increased risk of mental health problems. Further research is needed to establish the direction of causality., Patient Summary: We looked at the association between continence problems and mental health outcomes in young people from a large population-based cohort. Young people with continence problems at the age of 14 yr were more likely to suffer from a range of mental health problems at the age of 18 yr, including common mental disorder, depression, anxiety, self-harm thoughts, and disordered eating. Paediatric continence clinics should address the mental health needs of young people and provide clear and effective care pathways to child and adolescent mental health services., (Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.)
- Published
- 2023
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21. Editorial Comment on Frequency of tethered cord syndrome in pediatric patients with refractory daytime urinary incontinence.
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Shimura H
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- Child, Humans, Diurnal Enuresis, Urinary Incontinence epidemiology, Urinary Incontinence etiology, Urinary Incontinence therapy, Neural Tube Defects complications, Neural Tube Defects epidemiology, Neural Tube Defects surgery
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- 2023
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22. Daytime Wetting
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Wan, Julian, Klein, Eric A., Series editor, Rabinowitz, Ronald, editor, Hulbert, William C., editor, and Mevorach, Robert A., editor
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- 2014
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23. Robot assisted radical cystectomy with Florence robotic intracorporeal neobladder (FloRIN): Analysis of survival and functional outcomes after first 100 consecutive patients upon accomplishment of phase 3 IDEAL framework
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Andrea Mari, Giovanni Tasso, Fabrizio Di Maida, Andrea Minervini, Simone Sforza, Antonio Andrea Grosso, Giampaolo Siena, Lorenzo Masieri, Gianni Vittori, Marco Carini, Agostino Tuccio, Riccardo Tellini, and R. Bossa
- Subjects
Male ,medicine.medical_specialty ,Survival ,Functional features ,medicine.medical_treatment ,Operative Time ,030232 urology & nephrology ,Cystectomy ,Surgically-Created Structures ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Robotic Surgical Procedures ,medicine ,Humans ,Prospective Studies ,Aged ,Neoplasm Staging ,Nodal involvement ,Carcinoma, Transitional Cell ,business.industry ,Carcinoma in situ ,Open surgery ,General Medicine ,Middle Aged ,medicine.disease ,Surgery ,Transitional cell carcinoma ,Urinary Bladder Neoplasms ,Oncology ,Quartile ,030220 oncology & carcinogenesis ,Operative time ,Female ,Diurnal Enuresis ,business ,Carcinoma in Situ ,Learning Curve ,Follow-Up Studies ,Nocturnal Enuresis - Abstract
Aim of the study was to evaluate the Florence intracorporeal neobladder (FloRIN) oncological and functional outcomes at the end of assessment phase (phase 3) IDEAL-Guidelines.This single-institution prospective series included consecutive patients treated with robot-assisted radical cystectomy (RARC) and FloRIN reconfiguration technique from February 2016 to June 2020. Functional features were evaluated six months after surgery. Patients were grouped into four quartiles according to time of radical cystectomy and impact of learning curve improvement was evaluated.One-hundred FloRIN were completed with a median console time of 373 (IQR: 312-415) minutes. Two cases were converted to open surgery. No intraoperative complications occurred. At pathological examination, 30% of patients were staged as pT ≤ 1 and 47% as pT ≥ 3. Transitional cell carcinoma was present in 87% of cases. Carcinoma in situ (CIS) and nodal involvement were observed in 38% and 29% of patients, respectively. At a median follow-up time of 17 (IQR: 7-28) months, 20 clinically relevant events (Clavien-Dindo≥3) occurred. Operative time significantly decreased throughout the series (median minutes 435; 395; 365 and 330 in the four quartiles, respectively; p 0.001). Similarly, early Clavien-Dindo≥3 postoperative complications rate significantly decreased across the series (number of events: 1; 4; 0; 0; p = 0.03). Overall, 75% and 65% of patients achieved day-time and nigh-time continence, respectively. Twenty-seven patients experienced disease recurrence. Cancer-specific and overall survival were equal to 80%.RARC with FloRIN reconfiguration showed worthy functional and survival outcomes, with learning curve improvement significantly influencing operative time and early complications rate across series.
- Published
- 2021
24. Attention to detail: not simple bed wetting—Hinman–Allen syndrome
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Mannemuddhu, Sai Sudha, Bayne, Christopher E., Tufan Pekkucuksen, Naile, and Shoemaker, Lawrence R.
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- 2021
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25. Study protocol for a parallel-group randomized controlled multi-center trial evaluating the additional effect of continuous ultrasound bladder monitoring in urotherapy for children with functional daytime urinary incontinence (SENS-U trial)
- Author
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L. L. de Wall, A. J. Nieuwhof-Leppink, E. H. M. van de Wetering, E. Leijn, M. Trompetter, L. M. O. de Kort, W. F. Feitz, R. Schappin, and Dermatology
- Subjects
All institutes and research themes of the Radboud University Medical Center ,Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10] ,Urinary Incontinence ,Adolescent ,Urinary Bladder ,Quality of Life ,Medicine (miscellaneous) ,Humans ,Multicenter Studies as Topic ,Pharmacology (medical) ,Diurnal Enuresis ,Child ,Randomized Controlled Trials as Topic - Abstract
Background Lower urinary tract dysfunction or functional urinary incontinence is a common condition with a prevalence up to 21% between 6 and 8 year-old children. It is associated with an impaired quality of life, lower self-esteem, and social stigmatization. Urotherapy is the first treatment of choice for functional daytime urinary incontinence (DUI) in children. Alarm therapy can be a part of urotherapy as it provides the child adequate feedback on wetting accidents. Current alarm systems notify either at a set interval or give a notification when wetting has already occurred to prompt the child to go to the toilet. These alarms do not teach the child the interpretation of the bladder sensation preceding wetting accidents. A new wearable bladder sensor, the SENS-U, recently became available. This is a relative small, wireless ultrasonic sensor, which continuously monitors bladder filling. The SENS-U is able to provide an alarm at the exact moment voiding is warranted. It facilitates the child to learn the sensation of bladder filling preceding voiding in an easier way, increasing the learning curve throughout treatment. Its additional effect in urotherapy on continence and cost-effectiveness is to be determined. Methods/design This is a multi-center clinical superiority parallel-group randomized controlled trial including a total of 480 children. Participants between 6 and 16 years of age with functional DUI in which urotherapy is offered as the next treatment of choice are eligible. Four centers, two academic hospitals, and two general care (peripheral) centers are participating. Participants will be randomized at a 1:1:1 ratio into three groups: urotherapy (care as usual), urotherapy with the SENS-U added for 3 consecutive weeks throughout the training, or urotherapy with a SHAM device for 3 weeks. The primary outcome is number of wetting accidents per week after 3 months of training, compared between the SENS-U and the SHAM device. The magnitude of the placebo effect will be assessed by comparing the results of the SHAM group versus the control (care as usual) group. Discussion To our knowledge, this is the first trial studying not only the effect but also the cost-effectiveness of alarm interventions as commonly added in urotherapy. Trial registration ISRCTN44345202. Registered on March 2022
- Published
- 2022
26. Sex and age differences in lower urinary tract dysfunction in healthy children
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Pernilla Stenström, Anna Börjesson, Christina Granéli, Martin Salö, Kristine Hagelsteen, Mette Hambraeus, and Malin Carvahlo Nejstgaard
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Male ,medicine.medical_specialty ,Adolescent ,Urinary system ,Urinary incontinence ,Lower Urinary Tract Symptoms ,Lower urinary tract symptoms ,Enuresis ,Internal medicine ,medicine ,Humans ,Child ,Response rate (survey) ,Urinary tract function ,Age differences ,business.industry ,General Medicine ,medicine.disease ,Urinary Incontinence ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Daytime Urinary Incontinence ,Female ,Diurnal Enuresis ,medicine.symptom ,business ,Nocturnal Enuresis - Abstract
AIM Information about healthy children's urinary tract symptoms is scarce but would be helpful in children with congenital urinary tract conditions. The aim of this study was to develop and evaluate a Lower Urinary Tract Dysfunction (LUTD) questionnaire. METHODS A 15-item questionnaire based on definitions by the International Children's Continence Society (ICCS) about urinary tract function, was given to children 4-15 years old with no gastrointestinal or urinary tract conditions. The study was approved ethically. RESULTS The response rate was 82% (311/377), 50% (n = 155) were girls. Children were of the age groups 3.5-7 years (n = 136), 8-12 years (n = 127), and 13-15 years (n = 48). More girls than boys reported urinary tract infections (20% vs 3%, p
- Published
- 2021
27. Are lower urinary tract conditions more common in children with sleep bruxism?
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Ceyhan, Erman, Hasirci, Eray, Gezgin, Onur, Senirkentli, Guler Burcu, and Aygun, Yuksel Cem
- Abstract
Sleep bruxism is a parasomnia caused by rhythmic and non-rhythmic activity of the masticatory muscles during sleep. Prevalence of sleep bruxism is reported up to 40.6% in the literature. Sleep bruxism is a multifactorial issue and associated with multiple dental complications, sleep-related disorders, and psychosocial problems. We aimed to investigate if children with sleep bruxism suffer more from lower urinary tract conditions. Prospectively 128 children were included in this study. Sixty-four children constituted in the bruxism group and 64 children constituted in the control group. Children who admitted to the pediatric dentistry clinic with bruxism symptoms were recruited in the bruxism group. Control group constituted of consecutive 64 children who admitted to the pediatric dentistry clinic for routine dental examination. Parents were asked to fill out a questionnaire including Dysfunctional Voiding and Incontinence Scoring System (DVISS) form. Children's demographic data, presence of urinary frequency, presence of urgency, behaviour of voiding postponement, presence of daytime urinary incontinence, presence of enuresis nocturna, presence of fecal incontinence, presence of constipation, status of circumcision, and presence of bruxism related symptoms were recorded. Children with a DVISS score above 8 were considered to have functional voiding disorder. All children underwent a dental examination. The mean age of children was 73.3 ± 26.9 months. For all children (n = 128), the girl to boy ratio was 40:88. Mean DVISS score was 2.5 ± 3.8 and the mean QOL score was 0.1 ± 0.4 for all children. Eight (6.3%) children were found to have functional voiding disorder based on the DVISS score. There was no statistically significant difference for any lower urinary tract condition between the bruxism group and the control group (Table). Children with bruxism significantly had more tooth wear and masseter muscle hypertrophy (<0.001 and < 0.05). Sleep bruxism has been linked to a number of health issues including dental, systemic and psychosocial problems. Tooth wears, fatigue/pain in chewing muscles, gum recession, facial pain, masseter muscle hypertrophy and temporomandibular joint damage are the main complications of bruxism. Moreover, bruxism has been associated with systemic diseases and sypmtoms like asthma, respiratory illnesses, enuresis nocturna, anxiety, and stress. Children with sleep bruxism suffer more from tooth wear, masseter muscle hypertrophy, and regional pain over the jaw. Additionally morning fatigue, relationship issues, and respiratory illnesses are more common in bruxist children. Lower urinary tract conditions are not more frequent in children with sleep bruxism. Summary Table Lower urinary tract characteristics according to groups. Table Bruxism Group Control Group p value (n = 64) (n = 64) Urinary frequency (n, %) Yes 10 (15.6%) 11 (17.2%) 0.881 No 54 (84.4%) 53 (82.8%) Urgency (n, %) Yes 39 (60.9%) 35 (54.7%) 0.474 No 25 (39.1%) 29 (45.3%) Voiding Postponement (n, %) Yes 20 (31.2%) 17 (26.6%) 0.559 No 44 (68.8%) 47 (73.4%) Daytime urinary incontinence (n, %) Yes 3 (4.7%) 7 (10.9%) 0.188 No 61 (95.3%) 57 (89.1%) Enuresis nocturna (n, %) Yes 7 (10.9%) 6 (9.4%) 0.770 No 57 (89.1%) 58 (90.6%) DVISS Score (median, min–max) 1 (0–12) 1 (0–25) 0.675 QOL Score (median, min–max) 0 (0–3) 0 (0–2) 0.239 Functional voiding disorder (n, %) Yes 3 (4.7%) 5 (7.8%) 0.465 No 61 (95.3%) 59 (92.2%) [ABSTRACT FROM AUTHOR]
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- 2023
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28. Right Flank Pain and Diurnal Enuresis in a 14-Year-Old Male
- Author
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Maureen Nsofor, Erica L. Riedesel, and Anthony Cooley
- Subjects
Male ,Adolescent ,Pediatrics, Perinatology and Child Health ,Humans ,Flank Pain ,Diurnal Enuresis ,Enuresis - Published
- 2022
29. Pediatric urinary incontinence: Classification, evaluation, and management
- Author
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A.J. Schaeffer and D.A. Diamond
- Subjects
Urinary incontinence ,Diurnal enuresis ,Nocturnal enuresis ,Pediatrics ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Objective: To review the classification, evaluation, and management of pediatric urinary incontinence. Methods: An examination of texts and peer-reviewed literature was performed to identify subject matter relevant to the stated objectives, with the experience of the senior author used in cases where the literature failed to provide guidance. Results: On the basis of our review, we identified the International Children's Continence Society's (ICCS) statement standardizing the terminology for lower urinary tract function in children and present a logical classification scheme for incontinence. After an epidemiology review, we discuss the appropriate evaluation of the incontinent child, of which the cornerstones are a detailed history and thorough physical exam. Finally, a concise discussion of the management of daytime incontinence, nocturnal enuresis, and neurogenic and anatomic incontinence is presented, with deference to evidence-based approaches where available. Depending on the type of incontinence, the management strategies can include behavioral, pharmacologic, and/or surgical approaches. Conclusion: Pediatric urinary incontinence is a common condition which, after appropriate evaluation, can be successfully treated.
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- 2014
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30. Evaluation of boys with daytime incontinence by combined cystourethroscopy, voiding cystourethrography and urodynamics
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Lilia Winck-Flyvholm, Karen Damgaard Pedersen, Jorgen Thorup, and Simone Hildorf
- Subjects
Male ,medicine.medical_specialty ,Urology ,Urinary Bladder ,030232 urology & nephrology ,Urination ,Urinary incontinence ,030204 cardiovascular system & hematology ,urologic and male genital diseases ,03 medical and health sciences ,0302 clinical medicine ,Cystourethrography ,Urethra ,medicine ,Humans ,Child ,business.industry ,Cystoscopy ,medicine.disease ,humanities ,female genital diseases and pregnancy complications ,Urodynamics ,Overactive bladder ,Nephrology ,Daytime Urinary Incontinence ,Diurnal Enuresis ,medicine.symptom ,business - Abstract
Objects: Approximately, 1% of school children have daytime urinary incontinence. The symptoms may be caused by an overactive bladder (OAB). In the evaluation of boys with OAB complaints, one should...
- Published
- 2020
31. Incontinence and sleep disturbances in young children: A population-based study
- Author
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Alexander Gontard, Hannah Mattheus, Jana Friese‐Jaworsky, Anna‐Michaela Moritz, Sigrid Thome‐Granz, Sylvia Roozen, Leopold Curfs, Gommert Koeveringe, Justine Hussong, RS: MHeNs - R3 - Neuroscience, RS: GROW - R4 - Reproductive and Perinatal Medicine, Complexe Genetica, MUMC+: DA KG Polikliniek (9), Urologie, MUMC+: MA Urologie (3), and MUMC+: MA Urologie (9)
- Subjects
Male ,Sleep Wake Disorders ,preschool children ,HABITS QUESTIONNAIRE ,DISORDERS ,Urology ,CONSTIPATION ,fecal incontinence ,PSYCHOMETRIC PROPERTIES ,DIFFICULTIES QUESTIONNAIRE ,Child, Preschool ,Surveys and Questionnaires ,TODDLERS ,daytime urinary incontinence ,Humans ,Female ,psychological problems ,sleep disorders ,STRENGTHS ,Neurology (clinical) ,Diurnal Enuresis ,Child ,Sleep ,nocturnal enuresis - Abstract
Aims Nocturnal enuresis (NE), daytime urinary incontinence (DUI), fecal incontinence (FI), as well as sleep and behavioral problems are common in young children. The aim of this study was to analyze the association of sleep and psychological parameters for all types of incontinence in a representative sample of young children. Methods Six hundred thirty eight (of 1161) children with a mean age of 5.9 years (50.9% boys) were assessed during their mandatory school entry examination. The participation rate was 55%. Instruments included the Strengths and Difficulties Questionnaire, the Children's Sleep Habits Questionnaire and other clinical questions. Incontinence was diagnosed according to ICCS standards. Constipation was assessed by two questions. Results 17.1% of children had at least one type of incontinence, 14.8% had NE, 5.0% DUI, 2.1% FI, and 4.8% were constipated. 6.7% of children had clinically relevant psychological problems. 22.7% of children had sleep problems regularly (5-7 times/week). A wide variety of sleep problems were reported. Children with incontinence were not affected by a higher rate of sleep problems. Children with NE had fewer night wakings and those with constipation fewer parasomnias. Sleep and psychological problems were significantly associated, especially in children with DUI and FI. Conclusions Sleep and behavioral problems are common in young children. Psychological problems have a clear impact on sleep. Young children with incontinence do not have more sleep problems than continent children. Therefore, both sleep and psychological problems should be addressed in young children with incontinence.
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- 2022
32. Comparison and characteristics of children successfully treated for daytime urinary incontinence
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Luise Borch, Alexander Slot Jessen, and Soeren Hagstroem
- Subjects
Pediatrics ,medicine.medical_specialty ,Urology ,Anticholinergic ,Diurnal Enuresis/therapy ,Pharmacological treatment ,Overactive urinary bladder ,medicine ,Humans ,Prospective Studies ,Treatment outcome ,Child ,Retrospective Studies ,Standard urotherapy ,business.industry ,Urinary Bladder, Overactive ,Urinary Incontinence/diagnosis ,medicine.disease ,First line treatment ,Bowel dysfunction ,Urinary Incontinence ,Overactive bladder ,Urinary Bladder, Overactive/drug therapy ,Pediatrics, Perinatology and Child Health ,Daytime Urinary Incontinence ,Daytime urinary incontinence ,Diurnal Enuresis ,business ,Stepwise approach ,Pediatric population - Abstract
INTRODUCTION: Daytime urinary incontinence (DUI) is defined as an involuntary leakage of urine during daytime in children 5 years or older. It is a common disorder in the pediatric population most often caused by an overactive bladder (OAB). A stepwise approach is recommended in the treatment of DUI, with standard urotherapy (SU) being first line treatment followed by pharmacological treatment when SU is unsuccessful. To our knowledge few studies have compared patients achieving continence solely on urotherapy with patients achieving continence on a combination of urotherapy and pharmacological treatment in the pediatric population.OBJECTIVE: The aim of the study was to characterize and compare children suffering from OAB and DUI who became continent solely on urotherapy with patients achieving continence on a combination of urotherapy and pharmacological treatment.METHODS: All children successfully treated for DUI from 2015 to 2020 were retrospectively analyzed and compared using data from patient's records, 48-h flow-volume charts, and uroflowmetry analysis.RESULTS: 180 children were successfully treated for DUI. Of these 23 (13%) had bowel dysfunction, 94 (52%) were successfully treated with standard urotherapy (SU) and 64 (35%) needed pharmacological treatment. Children who achieved continence on a combination of SU and pharmacological treatment had a significantly higher baseline voiding frequency (7.6 and 6.5 respectively, p=0.007) and more baseline incontinence episodes during daytime when compared to children who became dry solely on urotherapy (2.2 and 1.1 respectively, p < 0.001). Both groups had a similar baseline age (p=0.96) and received a similar duration of standard urotherapy prior to the eventual pharmacological treatment (p = 0.73).DISCUSSION: Most children achieved daytime continence solely on standard urotherapy. We found that children requiring additional pharmacological treatment to achieve continence suffer from a more severe overactive bladder. As such it could be speculated that children with high voiding frequencies and multiple daily incontinence episodes may benefit from adding anticholinergics to SU earlier during the course of treatment, than what is recommended by the International Children's Continence Society (ICCS) today. However prospective interventional studies are needed for safe conclusions.CONCLUSION: Our comparison showed that children requiring a combination of SU and pharmacological treatment to achieve continence, had a significantly higher baseline voiding frequency and more baseline incontinence episodes when compared to children requiring only SU to achieve continence.
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- 2022
33. Transcutaneous electrical nerve stimulation as add-on therapy in children receiving anticholinergics and/or mirabegron for refractory daytime urinary incontinence:A retrospective cohort study
- Author
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Kristina Thorsteinsson, Søren Rittig, Natashja Pedersen, Anders Breinbjerg, Søren Hagstrøm, and Konstantinos Kamperis
- Subjects
URGE INCONTINENCE ,medicine.medical_specialty ,Constipation ,Adolescent ,medicine.drug_class ,Urology ,overactive ,Urinary incontinence ,urge ,Transcutaneous electrical nerve stimulation ,Cholinergic Antagonists ,law.invention ,transcutaneous electrical nerve stimulation ,law ,Internal medicine ,medicine ,Anticholinergic ,Humans ,Child ,Retrospective Studies ,Urinary bladder ,urinary incontinence ,PLACEBO ,Urinary Bladder, Overactive ,business.industry ,Retrospective cohort study ,medicine.disease ,EFFICACY ,mirabegron ,OVERACTIVE BLADDER ,OXYBUTYNIN ,Thiazoles ,Treatment Outcome ,medicine.anatomical_structure ,Overactive bladder ,Child, Preschool ,Transcutaneous Electric Nerve Stimulation ,MONOSYMPTOMATIC NOCTURNAL ENURESIS ,Acetanilides ,cholinergic antagonists ,Neurology (clinical) ,Diurnal Enuresis ,medicine.symptom ,Mirabegron ,business ,urinary bladder ,medicine.drug - Abstract
AIMS: To investigate if children with daytime urinary incontinence (DUI) and overactive bladder (OAB) refractory to standard urotherapy and medicinal treatment, would experience improvement in symptoms after add-on treatment with transcutaneous electrical nerve stimulation (TENS).METHODS: Children were retrospectively enrolled from tertiary referral centers at Aarhus and Aalborg University Hospitals. All data were retrieved from the patients' journals. All children were prescribed TENS as an add-on treatment to the highest-tolerable dose of medicinal treatment in a standardized regime of 2 h a day for around 3 months. Primary endpoints were the number of wet days per week (WDPW) and incontinence episodes per day. Effect of treatment was defined as greater or equal to 50% reduction in the frequency of DUI episodes. Secondary endpoints were to establish predictive factors for the effect of treatment using logistic regression.RESULTS: Seventy-six children diagnosed with DUI and OAB refractory to treatment with standard urotherapy and pharmacological treatment, at the age of 5-16 years were included from February 2017 to February 2020. A reduction in WDPW (from 6.31 [5.86-6.61] to 4.27 [3.45-4.90], p CONCLUSIONS: TENS as add-on to anticholinergic treatment seems effective in a number of children with treatment-refractory DUI.
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- 2022
34. Vibegron shows high efficacy in pediatric patients with refractory daytime urinary incontinence.
- Author
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Hyuga T, Tanabe K, Kubo T, Nakamura S, Nakai H, and Moriya K
- Subjects
- Male, Female, Humans, Child, Pyrimidinones therapeutic use, Cholinergic Antagonists therapeutic use, Diurnal Enuresis, Urinary Bladder, Overactive drug therapy
- Abstract
Purpose: Sparse published reports exist nowadays on vibegron and pediatric overactive bladder, so its usefulness of this agent remains unclear. The purpose of this study was to clarify the effectiveness of vibegron for pediatric cases of daytime urinary incontinence (DUI), including refractory cases., Methods: Participants comprised 57 patients treated with vibegron for DUI from March 2019 to April 2022. To investigate treatment outcomes and risk factors for pediatric patients with refractory DUI, the following factors were evaluated: age at initiatial administration; frequency of DUI; duration of vibegron treatment; presence of neurodevelopmental disorders (NDDs); presence of constipation; and anticholinergic medications before and after initiation of treatment., Results: Patients included 38 boys and 19 girls with a median age at initial administration of 111 months (range: 64-202 months) and a median administration term of 6 months (range: 1-33 months). With treatment for 6 months, the response rate (complete response + partial response) was 68.3%. A total of 24 cases with NDD showed a 72.0% response rate at 6 months. As for the relationship between anticholinergic agents and vibegron, 15 cases were treated with vibegron as the first choice without anticholinergics (First-choice cases), and 33 cases were treated with vibegron alone after switching from anticholinergics (Switch cases). Vibegron was used in combination with anticholinergic agents in 9 cases (Add-on cases). Response rates at 6 months were 85.0% in First-choice cases, 66.3% in Switch cases, and 40.7% in Add-on cases. Univariate analyses failed to identify any significant risk factors for refractory cases., Conclusions: Vibegron was effective in pediatric cases of DUI, with efficacy demonstrated within a short time in many cases. Vibegron is expected to play a significant role in the treatment of DUI in pediatric cases., (© 2023 Wiley Periodicals LLC.)
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- 2023
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35. Attention to detail: not simple bed wetting—Hinman–Allen syndrome
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Naile Tufan Pekkucuksen, Sai Sudha Mannemuddhu, Christopher E. Bayne, and Lawrence R. Shoemaker
- Subjects
Bed-wetting ,Nephrology ,business.industry ,Simple (abstract algebra) ,Calculus ,medicine ,Diurnal enuresis ,medicine.symptom ,business - Published
- 2020
36. Comentary on 'Comparison and characteristics of children successfully treated for daytime urinary incontinence'
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Isabel Casal-Beloy, Blanca Capdevila-Vilaró, Sonia Pérez-Bertólez, Oriol Martín-Solé, Miriam García González, Xavier Tarrado Castellarnau, and Luís García-Aparicio
- Subjects
Urinary Incontinence ,Urology ,Surveys and Questionnaires ,Pediatrics, Perinatology and Child Health ,Humans ,Diurnal Enuresis ,Child - Published
- 2021
37. A scoping study of paediatric continence service provision in the Great Southern region of Western Australia.
- Author
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Goetze, Emma, McLean, Katherine, Thompson, Judith, Jacques, Angela, and Briffa, Kathy
- Abstract
The aim in conducting this cross-sectional study was to survey 100 parents of children in pre-primary and year one in the Great Southern region of Western Australia to determine the number of children with urinary incontinence and, of those, how many were receiving treatment. The severity and associated risk factors were also investigated. Permission was sought from schools to recruit parents of children starting primary school to complete an online survey. Social media was used to enhance response rates. The response rate was 100/1665 (6%) of the total target population, 100/925 (10.8%) of children from participating schools. Overall, 40% of responders reported daytime urinary incontinence. Of the children with daytime urinary incontinence, 26.3% experienced mild and 73.7% moderate-severe daytime urinary incontinence. No child was reported to have severe daytime urinary incontinence. Nocturnal enuresis was reported in 46.9% of those who responded and 89.8% of children suffered from at least one other lower urinary tract symptom. This study is significant as there are limited treatment options in regional Australia for paediatric daytime urinary incontinence. Only 23.7% of parents had sought medical treatment for their affected child. Further research is required to determine whether lack of parental awareness regarding the significance of incontinence and the availability of treatment services; or the lack of accessible services in regional and rural Australia is behind inadequate intervention for this condition. Larger sample sizes are required to accurately determine prevalence and to examine risk factors for daytime urinary incontinence in children. [ABSTRACT FROM AUTHOR]
- Published
- 2016
38. Urinary incontinence during laughter in children: Is it giggle incontinence?
- Author
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Elizabeth H Barnes, Patrina H Y Caldwell, and Soe T San
- Subjects
medicine.medical_specialty ,Provisional diagnosis ,media_common.quotation_subject ,Urinary incontinence ,Laughter ,03 medical and health sciences ,0302 clinical medicine ,Lower urinary tract symptoms ,030225 pediatrics ,Medicine ,Humans ,Family ,030212 general & internal medicine ,Psychiatry ,Child ,media_common ,Retrospective Studies ,business.industry ,Medical record ,medicine.disease ,Giggle incontinence ,Urinary Incontinence ,Pediatrics, Perinatology and Child Health ,Daytime Urinary Incontinence ,Diurnal enuresis ,medicine.symptom ,Diurnal Enuresis ,business - Abstract
Aim Giggle incontinence is a distinct entity of childhood daytime urinary incontinence (DUI), where children wet themselves only when they laugh. The prevalence of true giggle incontinence is unknown, with confusion about the diagnosis of urinary incontinence occurring during laughter and true giggle incontinence. The aim of the study is to improve our understanding of urinary incontinence during laughter by comparing those children with children who have DUI at other times, but not with laughter. Methods We conducted a retrospective medical record review of children with DUI who presented to a tertiary continence service from 2017 to 2018, collecting data on age, gender, associated comorbidities, lower urinary tract symptoms, investigations, provisional diagnosis at first visit and initial treatment responses. Differences between those with DUI occurring during laughter and those with DUI at other times, but not with laughter were compared using standard statistical methods. Results Of the 277 new patients seen during the study period, 140 (51%) had DUI, and of these, 72 (51%) had DUI occurring during laughter. Children with incontinence occurring during laughter were more likely to have incontinence associated with other activities. One child had giggle incontinence according to the International Children's Continence Society's definition. Four other children were referred specifically for urinary incontinence associated with laughter, with the term giggle incontinence sometimes used by the referring doctor. Conclusion Children with DUI commonly experience incontinence during laughter, but true giggle incontinence is rare. Correct diagnosis is essential as it directs treatment.
- Published
- 2021
39. Bupropion Hydrochloride Sustained Release and Diurnal Enuresis: A Previously Unreported Adverse Effect
- Author
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Glenn Catalano, Raj A Patel, Anjali Nirmalani-Gandhy, and Theresa A. Schwitalla
- Subjects
Male ,Pharmacology ,03 medical and health sciences ,0302 clinical medicine ,mental disorders ,Humans ,Medicine ,Pharmacology (medical) ,Adverse effect ,Bupropion ,business.industry ,Middle Aged ,Antidepressive Agents ,030227 psychiatry ,Regimen ,Tolerability ,Delayed-Action Preparations ,Antidepressant ,Neurology (clinical) ,Bupropion hydrochloride ,Diurnal Enuresis ,Diurnal enuresis ,medicine.symptom ,business ,Reuptake inhibitor ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Bupropion hydrochloride (HCl) is an antidepressant that has many different biological targets, acting as both a norepinephrine-dopamine reuptake inhibitor as well as a nicotinic antagonist. This second-generation antidepressant is available in 3 bioequivalent formulations: immediate release, sustained release, and extended release, allowing providers to customize a patient's regimen for maximum tolerability and compliance. Although bupropion HCl's safety and tolerability have been demonstrated through several clinical trials, there are still a number of adverse effects that have been reported in the literature. These include headache, agitation, tremor, and insomnia. There is also an increased risk of developing seizures during bupropion treatment. Although urinary symptoms were noted during the clinical trials, these are relatively rare adverse effects. Here we report the case of a 61-year-old man who developed diurnal enuresis during treatment with bupropion HCl sustained release. We will review the adverse effect burden associated with the use of bupropion and discuss the neuropharmacology of urinary symptoms associated with antidepressant treatment.
- Published
- 2019
40. Incontinence and headache in preschool children
- Author
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Cornelia Overs, Sigrid Thomé-Granz, Justine Hussong, Alexander von Gontard, and Anna-Michaela Moritz
- Subjects
Male ,medicine.medical_specialty ,Pediatrics ,Headache Disorders, Primary ,preschool children ,Constipation ,Migraine Disorders ,Urology ,Population ,030232 urology & nephrology ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Enuresis ,Surveys and Questionnaires ,Epidemiology ,Headache Disorders, Secondary ,medicine ,Humans ,Fecal incontinence ,migraine ,Child ,education ,nocturnal enuresis ,education.field_of_study ,030219 obstetrics & reproductive medicine ,business.industry ,Tension-Type Headache ,medicine.disease ,fecal incontinence ,Urinary Incontinence ,Migraine ,Child, Preschool ,daytime urinary incontinence ,Daytime Urinary Incontinence ,Female ,epidemiology ,Neurology (clinical) ,Diurnal Enuresis ,medicine.symptom ,Headaches ,business ,headache - Abstract
Aims Headaches in preschool children are associated with behavioral and gastrointestinal symptoms. As the co-occurrence with incontinence is not known in young children, the aim of the study was to examine associations of headache, psychological symptoms and nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) in a population-based sample of preschool children. Methods All preschool children of a defined geographical area were examined at school-entry. Parents completed a 22-item questionnaire, including 14 headache, 4 incontinence, and 25 items of the Strength and Difficulties Questionnaire (SDQ). Five hundred eighty-five children (50.4% males) with a mean age of 5.8 years were included. Results In total, 27.2% of all children had headaches. 15.7% had secondary and 11.3% primary headaches. Five children had migraine and five tension-type headaches, while all others were unclassifiable. 9.4% of children had incontinence (7.7% NE; 2.4% DUI, 1.2% FI) and 4.0% constipation. The rates of incontinence did not differ between children with primary and those without headache for NE (12.9% vs 7.5%), DUI (3.1% vs 2.7%) or FI (3.0% vs 1.0%), but for constipation (12.1% vs 2.6%). Incontinent children had significantly more behavioral and externalizing symptoms, children with headache more internalizing problems. Primary headache was a significant predictor for internalizing, while constipation and FI were predictors for externalizing symptoms. Conclusions This population-based study showed that headache is associated with constipation, but not with incontinence in preschool children. Headache and incontinence are common risk factors for specific psychological symptoms and should be assessed in clinical practice.
- Published
- 2019
41. Detailed Assessment of Incontinence, Psychological Problems and Parental Stress in Children with Autism Spectrum Disorder
- Author
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Theresa Link, Justine Niemczyk, Alina Burau, Roman Fischer, Catharina Wagner, and Alexander von Gontard
- Subjects
Male ,Parents ,Autism Spectrum Disorder ,behavioral disciplines and activities ,03 medical and health sciences ,0302 clinical medicine ,Enuresis ,mental disorders ,Developmental and Educational Psychology ,medicine ,Humans ,Outpatient clinic ,Fecal incontinence ,0501 psychology and cognitive sciences ,Child ,Child rearing ,05 social sciences ,medicine.disease ,Autism spectrum disorder ,Child, Preschool ,Autism ,Female ,Parental stress ,Diurnal Enuresis ,medicine.symptom ,Psychology ,Fecal Incontinence ,Stress, Psychological ,030217 neurology & neurosurgery ,Nocturnal Enuresis ,050104 developmental & child psychology ,Clinical psychology ,Psychopathology - Abstract
Incontinence, psychological symptoms, parental stress and psychopathology were examined in 51 children (43 boys, mean age = 9.7 years) presented in an outpatient clinic for autism spectrum disorders (ASD) and in 53 matched controls (43 boys, mean age = 10.2 years). All children were clinically assessed for ASD, incontinence and psychopathology according to current guidelines. ASD was confirmed in 37 children and excluded in 14. Enuresis (16.2%) and daytime urinary incontinence (16.2%), but not fecal incontinence (8.2%) were more common in ASD than in controls. Children with ASD showed significantly more comorbid psychiatric disorders. Parents of children with ASD experience more stress. Parental stress was predicted by parental psychopathology, role restriction and group (patient/control), but not by incontinence.
- Published
- 2019
42. Incontinence in autism spectrum disorder
- Author
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A. von Gontard, Catharina Wagner, and Justine Niemczyk
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,genetic structures ,Autism Spectrum Disorder ,behavioral disciplines and activities ,03 medical and health sciences ,0302 clinical medicine ,Child Development ,Enuresis ,mental disorders ,Developmental and Educational Psychology ,medicine ,Child and adolescent psychiatry ,Prevalence ,Fecal incontinence ,Humans ,0501 psychology and cognitive sciences ,Psychiatry ,Child ,Encopresis ,Functional incontinence ,05 social sciences ,General Medicine ,medicine.disease ,Psychiatry and Mental health ,Autism spectrum disorder ,Pediatrics, Perinatology and Child Health ,Autism ,Female ,medicine.symptom ,Diurnal Enuresis ,Psychology ,030217 neurology & neurosurgery ,Fecal Incontinence ,050104 developmental & child psychology ,Psychopathology ,Clinical psychology ,Nocturnal Enuresis - Abstract
Autism spectrum disorders (ASD) are defined by persistent deficits in reciprocal social interaction, communication, and language, as well as stereotyped and repetitive behavior. Functional incontinence, as well as ASD are common disorders in childhood. The aim of this systematic review was to give an overview of the co-occurrence of nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) in ASD, and vice versa, of ASD in children with incontinence. A systematic literature search of the terms “incontinence”, “enuresis”, and “encopresis” in combination with “autism” or “Asperger” in four databases (Scopus, PubMed, PsycInfo and Web of science) was conducted. All studies that examined incontinence frequencies in samples with ASD, and studies that measured frequencies of ASD diagnoses or symptoms in samples with incontinence were included. Risk of bias and limitations of each study were described. After eligibility assessment, 33 publications were included in the review. The published literature implies a higher prevalence of incontinence in children with ASD compared to typically developing children. Limitations and biases as inappropriate diagnostic criteria for ASD and incontinence, selected samples, or lack of control groups are reported. Associations of incontinence in ASD with psychopathological symptoms were found. Vice versa, ASD symptoms are found in incontinent children, but no study included a non-ASD control sample. Incontinence symptoms are also reported as an adverse effect of medication in ASD. Due to methodological problems and definitional discrepancies in some publications, results have to be interpreted cautiously. Research in ASD and incontinence is scarce. More systematic research including state-of-the-art assessments is needed.
- Published
- 2018
43. The Relationship between mouth breathing and nocturnal diurnal enuresis in children
- Author
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Farbod M. and Niaki E.A.
- Subjects
Nocturnal enuresis ,Diurnal enuresis ,Medicine ,Dentistry ,RK1-715 - Abstract
Enuresis during childhood disturbs children both physically and emotionally. It reduces their"nself-confidence and so causes many personal and social problems."nDifferent ways of treating this problem have been suggested and carried out, but none of them have been"na total success. But one way is to change from mouth breathing to nose breathing."nEnuresis in 6 Patient out often was totally cured and in three other patients who's mouth breathing all"naltered to mouth- nose breathing it was reduced, approximately to the extended of a half."nOne who's mouth breathing was not subject to any change enuresis was not remedied either."nOn the whole, it could be concluded that the conversion of mouth breathing to nose breathing would"nsolve enuretic difficulties to a certain extend.
- Published
- 1999
44. Parents' expectations of the outpatient care for daytime urinary incontinence in children: A qualitative study
- Author
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Janita L A Ekelmans-Hogenkamp, Gertine Kroes-van Hattem, J. Marleen Linde, Marco H. Blanker, Martijn G Steffens, Rien J.M. Nijman, Ilse Hofmeester, Francis J Kloosterman-Eijgenraam, and Life Course Epidemiology (LCE)
- Subjects
Parents ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,030232 urology & nephrology ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Ambulatory care ,Enuresis ,030225 pediatrics ,Ambulatory Care ,Medicine ,Outpatient clinic ,Humans ,Child ,Motivation ,business.industry ,Social impact ,Family medicine ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Daytime Urinary Incontinence ,Quality of Life ,medicine.symptom ,Diurnal Enuresis ,business ,Watchful waiting ,Qualitative research - Abstract
INTRODUCTION: Daytime urinary incontinence (UI) can have an enormous impact on a child's life, lowering both self-esteem and quality of life. Although most children start therapy after their first visit to our outpatient clinic, no studies have reported on parents' or patients' expectations of care for daytime UI in this setting.OBJECTIVE: We aimed to explore the expectations of the parents of children referred to an outpatient clinic for daytime UI.STUDY DESIGN: This was a qualitative study that involved performing semi-structured interviews with the parents of children who had been referred for daytime UI (with or without nocturnal enuresis). Interviews took place between July 2018 and October 2018 and continued until saturation was reached. The results were transcribed verbatim and analyzed according to Giorgi's strategy of phenomenological data analysis.RESULTS: Nine parents of children, aged 5-12 years old, were interviewed, revealing "(Experienced) Health," Self-management," and "Social Impact" as the main themes that influenced parental expectations. All parents wanted to know if there was a medical explanation for UI, some were satisfied when diagnostics revealed no underlying condition, and others wanted treatment. Parents expressed no preferences about diagnostics or the content and duration of treatment, but they hoped that any previously attempted ineffective steps would not be repeated. Some parents defined treatment success as their child becoming completely dry, but most stated that learning coping strategies was more important.DISCUSSION: This is the first study to explore the expectations of parents when attending outpatient care for children with daytime UI. We employed a strong theoretical framework with a clear interview guide. The main limitations are that we only interviewed parents and that this was a qualitative study, precluding the drawing of firm conclusions. Nevertheless, our results point to the need for quantitative evaluation.CONCLUSION: Expectations seem to be influenced by (experienced) health, efforts at self-management, and the social impact of UI, making it critical that these themes are addressed. It was interesting to note that parents do not always attend outpatient departments with the goal of completely resolving daytime UI. Instead, some only want to know if there is an underlying medical condition or want to reduce the social impact by learning coping mechanisms. Excluding underlying medical conditions may therefore stimulate acceptance of watchful waiting without the need to start treatment.
- Published
- 2020
45. Prevalence of Daytime Urinary Incontinence and Related Risk Factors in Primary School Children in Turkey.
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Bolat, Deniz, Acar, Ismail Cenk, Zumrutbas, Ali Ersin, Eskicorapci, Saadettin, Sancak, Eyup Burak, Zencir, Mehmet, Turan, Tahir, and Sinik, Zafer
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- *
DISEASE prevalence , *URINARY incontinence , *SCHOOL children , *SOCIODEMOGRAPHIC factors , *DISEASE risk factors , *JUVENILE diseases - Abstract
Purpose: Urinary incontinence is one of the major urinary symptoms in children and adolescents and can lead to major distress for the affected children and their parents. In accordance with the definitions of the Standardization Committee of the International Children's Continence Society, daytime urinary incontinence (DUI) is uncontrollable leakage of urine during the day. The aim of this cross-sectional study was to investigate the prevalence and associated risk factors of DUI in Turkish primary school children. Materials and Methods: The questionnaire, which covered sociodemographic variables and the voiding habits of the children, was completed by the parents of 2,353 children who were attending primary school in Denizli, a developing city of Turkey. The children's voiding habits were evaluated by use of the Dysfunctional Voiding and Incontinence Symptoms Score, which is a validated questionnaire. Children with a history of neurological or urological diseases were excluded. Results: The participation rate was 91.9% (2,164 people). The overall prevalence of DUI was 8.0%. The incidence of DUI tended to decrease with increasing age and was not significantly different between genders (boys, 8.8%; girls, 7.3%; p=0.062). Age, maternal education level, family history of daytime wetting, settlement (urban/rural), history of constipation, urinary tract infection, and urgency were independent risk factors of DUI. Conclusions: Our findings showed that DUI is a common health problem in primary school children. In an effort to increase awareness of children's voiding problems and the risk factors for urinary dysfunction in the population, educational programs and larger school-based screening should be carried out, especially in regions with low socioeconomic status. [ABSTRACT FROM AUTHOR]
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- 2014
- Full Text
- View/download PDF
46. [Elimination disorders - ICD-11 classification and definitions]
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Alexander, von Gontard
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Elimination Disorders ,International Classification of Diseases ,Humans ,Diurnal Enuresis ,Child ,Fecal Incontinence ,Nocturnal Enuresis - Abstract
Elimination disorders - ICD-11 classification and definitions
- Published
- 2020
47. Definitions, indications and practice of urotherapy in children and adolescents: - A standardization document of the International Children's Continence Society (ICCS)
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Stephen Shei-Dei Yang, Piet Hoebeke, A.J. Nieuwhof-Leppink, A. von Gontard, J. Larsson, Janet Chase, Catherine Renson, and Justine Hussong
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medicine.medical_specialty ,Adolescent ,Urology ,medicine.medical_treatment ,030232 urology & nephrology ,Psychological intervention ,Urination ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Enuresis ,030225 pediatrics ,medicine ,Fecal incontinence ,Humans ,Child ,business.industry ,Reference Standards ,medicine.disease ,Urinary tract disorder ,Cognitive behavioral therapy ,Pediatrics, Perinatology and Child Health ,Physical therapy ,Quality of Life ,Functional constipation ,medicine.symptom ,Diurnal Enuresis ,business ,Psychosocial ,Nocturnal Enuresis - Abstract
Summary Background Urotherapy is an umbrella term for all non-surgical, non-pharmacological interventions for lower urinary tract disorders (LUTD) in children and adolescents. Urotherapy is a specialized practice, which has become mainstay therapy not only for daytime urinary incontinence, but also for nocturnal enuresis, functional constipation and fecal incontinence. The aim of urotherapy is to achieve the normalization of the micturition and bowel pattern and to prevent further functional disturbances by repeated training. It is well known that in the treatment of adult and childhood incontinence a team approach is best, where there are shared areas of expertise and also discipline-specific expertise available. Aim We present a consensus view from a cross-professional team of experts affiliated with the International Children's Continence Society on definitions, indications and practice of urotherapy. This is a selective, non-systematic review with practical recommendations for the implementation and research on urotherapy. Methods The document uses the globally accepted ICCS terminology. Evidence-based literature serves as the basis, but in areas lacking in primary evidence, expert consensus is used. Before submission, a full draft was made available to all ICCS members for additional comments. Results Urotherapy uses non-pharmacological, non-surgical methods and focuses on behavioral interventions, largely based on cognitive-behavioral psychotherapy (CBT). Standard urotherapy comprises components such as provision of information, instructions, life-style advice, counselling and registration of symptoms. Specific urotherapy is tailored towards specific disorders and includes alarm treatment, biofeedback training, pelvic floor training, neurostimulation and other interventions. Fig. 1. Urotherapy is a treatment that addresses all aspects of incontinence, leading to the best clinical outcome. This includes somatic, psychosocial, and behavioral problems and quality of life. Therefore urotherapy is recommended by the ICCS as the first-line treatment for most types of LUTD. The document is intended to be clinically useful in primary, secondary and tertiary care. Download : Download high-res image (226KB) Download : Download full-size image Summary Figure 1 . Daytime urinary incontinence and enuresis.
- Published
- 2020
48. Incontinence and constipation in adolescent patients with anorexia nervosa : Results of a multicenter study from a German web-based registry for children and adolescents with anorexia nervosa
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Stefan Ehrlich, Catharina Wagner, Beate Herpertz-Dahlmann, Tobias Renner, Christoph U. Correll, Christian Fleischhaker, Veit Roessner, Jens P. Pfeiffer, Katja Becker, Tanja Legenbauer, Ida Wessing, Karin Egberts, Michael Kaess, Ulrike M. E. Schulze, Judith Sinzig, Katharina Bühren, Alexander von Gontard, Freia Hahn, Charlotte Jaite, Johannes Hebebrand, Hannah K. Mattheus, Manuel Föcker, and Ekkehart Jenetzky
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Male ,medicine.medical_specialty ,Pediatrics ,Constipation ,Adolescent ,Population ,Medizin ,Physical examination ,anorexia nervosa ,body weight ,Enuresis ,Germany ,Surveys and Questionnaires ,Epidemiology ,Medicine ,Fecal incontinence ,Humans ,Registries ,education ,Child ,nocturnal enuresis ,education.field_of_study ,medicine.diagnostic_test ,business.industry ,constipation ,medicine.disease ,Comorbidity ,Psychiatry and Mental health ,Anorexia nervosa (differential diagnoses) ,daytime urinary incontinence ,Female ,medicine.symptom ,Diurnal Enuresis ,business ,Fecal Incontinence - Abstract
OBJECTIVE: Nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI) are common disorders in childhood and are frequently accompanied by comorbid psychiatric disorders. Despite a high association between urinary and fecal incontinence with psychiatric and neurodevelopmental disorders, research on comorbidity between incontinence and anorexia nervosa (AN) remains scarce. Yet, it is well known that somatic consequences of AN include metabolic and gastrointestinal disorders. The study sought to assess the prevalence of incontinence and constipation in children and adolescents with AN and to examine associations of these two symptoms with body weight at admission and with BMI changes during inpatient treatment. METHODS: Data collected between 2015 and 2017 by a multicenter German web-based registry for AN were analyzed. Three hundred and forty-eight patients with AN (96.3% female, mean age = 15.1 ± 1.8 years) were assessed regarding AN subtype, psychiatric comorbidity, body weight, incontinence, and constipation. RESULTS: Overall, 27.6% of patients had constipation, 1.8% had NE and 1.8% DUI. Prevalence of constipation did not significantly differ between AN subtypes. Constipation did not lead to any significant differences in weight/BMI changes during inpatient treatment. DISCUSSION: This is the largest study of incontinence and constipation in patients with AN, so far. Our results indicate that constipation is highly prevalent in adolescent patients with AN and reflects a clinically relevant condition. Despite, patients with AN do not have an increased prevalence of incontinence compared with the general population. Future studies should include medical examinations like ultrasound and physical examination of the lower abdomen to evaluate the severity of constipation.
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- 2020
49. Right Flank Pain and Diurnal Enuresis in a 14-Year-Old Male.
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Nsofor M, Riedesel EL, and Cooley A
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- Adolescent, Flank Pain etiology, Humans, Male, Diurnal Enuresis, Enuresis
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- 2022
- Full Text
- View/download PDF
50. Complete resolution of urinary incontinence with treatment improved the health-related quality of life of children with functional daytime urinary incontinence: a prospective study
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Takashi Kyoda, Masaki Fuyama, Chisato Oyake, Setuko Tamura, Yuta Oonuki, Hirokazu Ikeda, and Tsuneki Watanabe
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Male ,Quality of life ,medicine.medical_specialty ,030232 urology & nephrology ,Urinary incontinence ,lcsh:Computer applications to medicine. Medical informatics ,Group B ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,medicine ,Improvement ,Humans ,Prospective Studies ,Prospective cohort study ,Child ,Health related quality of life ,business.industry ,Research ,Public Health, Environmental and Occupational Health ,General Medicine ,Complete resolution ,Treatment Outcome ,Case-Control Studies ,Daytime Urinary Incontinence ,Physical therapy ,Daytime urinary incontinence ,Population study ,lcsh:R858-859.7 ,Female ,Self Report ,medicine.symptom ,Diurnal Enuresis ,business - Abstract
Background To assess the health-related quality of life (HRQOL) of children with daytime urinary incontinence (DUI) based on pre- and post-treatment self-reports and parent proxy-reports. Methods The study population comprised 117 children with at least one episode of DUI per week and their caregivers as well as 999 healthy children (control group). The Pediatric Quality of Life Inventory 4.0 (PedsQL) questionnaire was administered to assess the HRQOL of children. To assess the degree of improvement in HRQOL, we categorized children into two groups: group A achieved complete response (CR) to treatment within 12 months and group B did not achieve CR within 12 months. CR was defined as the complete resolution of symptoms or alleviation of symptoms to Results Valid responses were collected from 84 children [53 boys and 31 girls; mean age: 7.9 ± 1.5 years (range, 6–12)]. Sixty-two patients (73.8%) were classified into group A and 22 (26.1%) into group B. Based on self-reports, significant post-treatment improvement was observed in the scores of all PedsQL items (mean total score: 82.2 ± 11.3 vs. 87.2 ± 9.8; P = 0.003). Group A showed significant improvement in the scores of all PedsQL items after achievement of CR based on child self-reports; however, this was improvement not observed in group B. Conclusions To the best of our knowledge, this is the first study to demonstrate the complete resolution of DUI with treatment for improving the HRQOL of these children.
- Published
- 2019
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