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Cysticercosis, a major health issue in developing countries, is caused by the larval stage of Taenia solium. Disseminated cysticercosis (DCC), which is characterized by widespread cysticerci in various tissues, is rare and often asymptomatic. Here, we report the case of a 50-year-old man from rural Nepal with distal cholangiocarcinoma and DCC involving the skin, brain, orbit, tongue, soft palate, heart, and abdominal organs. Despite the presence of abdominal pain, obstructive jaundice, anemia, and significant weight loss—symptoms indicative of biliary malignancy—there were no symptoms typical of DCC. Diagnostic imaging confirmed DCC and stomach-preserving pancreaticoduodenectomy was performed. Histopathological examination of the periampullary mass revealed distal cholangiocarcinoma. Postsurgical treatment for DCC included steroids, carbamazepine, and antiparasitic therapy with albendazole. The coexistence of cysticercosis and neoplasia, though uncommon, necessitates thorough diagnostic evaluation. This case underscores the clinical complexity and highlights the need for comprehensive management of concurrent conditions.

Background: Cysticercosis is a zoonotic parasitic disease that poses a serious threat to public health. It is widely distributed and has a high incidence rate in China. Reports of disseminated cysticercosis worldwide are rare. This article presents a case of disseminated cysticercosis in the Guangxi Zhuang Autonomous Region of southwestern China. Case presentation: The patient, a 46-year-old male belonging to the Miao ethnic group, hailed from a region in Guangxi Zhuang Autonomous Region known for its high incidence of cysticercosis. He had a habit of consuming raw pork and beef. With a history of recurrent consciousness disturbances and limb convulsions for five years, he presented with headaches and dizziness nine days prior. Comprehensive examinations were conducted on the patient. Ultimately, based on epidemiological history, imaging findings, pathogen testing, and pathological results, he was diagnosed with disseminated cysticercosis. Following anthelmintic treatment, the patient was discharged with clear consciousness, free from headaches, dizziness, nausea, vomiting, and seizures. The patient is currently under follow-up care. Conclusion: It is crucial to enhance public awareness, promote health education, and cultivate good hygiene habits, as these are essential measures in reducing the incidence of cysticercosis. [ABSTRACT FROM AUTHOR]

Human cysticercosis, caused by the parasitic infection of Taenia Solium, is an important challenge for public health in Ecuador and other countries where poor sanitary conditions are a key factor for its appearance. In this series of cases, we publish the imaging findings corresponding to three patients treated in 2022 at the Center of Medical Specialties "Comité del Pueblo" Quito - Ecuador, in which, through radiographic images, multiple radiodense lesions were found in different anatomical regions which follow the typical pattern of distribution parallel to the muscular tissues of the affected region, generating the radiological sign known as "rice grain calcifications", which corresponds to the presence of Disseminated Cysticercosis (DCC)in the muscular tissue of the host. [ABSTRACT FROM AUTHOR]

Cysticercus cellulosae is the larval form of the pork tapeworm, Taenia solium. It can be transmitted to humans through food and water contaminated with eggs. The cysticerci formed are spread through the intestinal wall and are carried by the blood stream to muscles, brain, and subcutaneous tissues, leading to clinical manifestations. Rarely, disseminated cysticercosis is observed. We present a case of an asymptomatic disseminated cysticercosis in a 55‑year‑old man who presented with multiple subcutaneous nodules over the body for 1 year. A nodule was also present over the dorsum of the tongue. No systemic symptoms were associated. The diagnosis was made based on histopathology which revealed cystic lesions with larvae. Ultrasonography showed a cystic cavity with a scolex. On further investigations, involvement of the brain and thyroid gland were revealed. A high index of suspicion with appropriate investigations is required in such cases in endemic areas. Also, this raises the importance of thorough investigations, which should be performed to rule out disseminated disease even in the absence of systemic symptoms. [ABSTRACT FROM AUTHOR]

Abstract Background The management of disseminated cysticercosis is unclear and largely considered hazardous. The role of albendazole remains controversial in such patients. Methods A tertiary care, University hospital-based prospective intervention study was conducted from December 2015 to December 2017. Patients with disseminated cysticercosis, defined as the presence of multiple viable neurocysticerci (≥ 3) in the brain along with involvement of an additional extra site, were included in the study. Patients with cysticercal encephalitis were excluded. A detailed evaluation, including ophthalmoscopy, ocular B scans, ultrasound abdomen, and X-rays were done. Albendazole was administered at a dose of 15 mg/kg/day in 3 cycles of 28 days each. All patients were also given adjuvant corticosteroids and anti-epileptic drugs. Clinical and radiological follow up was carried out at a difference of 3 months between each treatment cycle. For radiological quantification, lesions were counted at 10 pre-specified levels. Statistical analysis was done to estimate the difference in seizure frequency and lesion load. Results Twenty-nine patients (21 with > 20 lesions; 8 with ≤ 20 lesions) were given albendazole as per the protocol. There was a significant reduction in the occurrence of seizures (P

Abstract Background Cysticercosis is an emerging and neglected tropical disease (NTD) that poses a serious public health concern worldwide. Disseminated cysticercosis (DCC) is an uncommon manifestation of cysticercosis, also found in China. Case presentation We report three cases of DCC in patients living in China, with different clinical and radiological presentations. All three patients had DCC with active ocular cysticercosis, including one patient with widespread DCC caused by direct ingestion of Taenia solium eggs. The intravitreal cysticercus cyst in this patient was completely extracted entirely by 23-gauge pars plana vitrectomy, and the cyst was oval in shape on the flat mount preparation. Conclusion The clinical presentation of DCC is highly sophisticated. The diagnosis depended on the typical radiological presentations, biopsy and flat mount preparations of the cyst.

Cysticercosis is a neglected tropical disease set as health priority by WHO. Most of the reported cases included isolated types of cysticercosis affecting the skin, the eyes or the brain. Disseminated types, however, are rare. We here report a case of disseminated cysticercosis affecting the brain, the eyes and the skin in a Senegalese female patient aged 66 years admitted with headaches and chronic seizures. Clinical examination showed cerebellar syndrome associated with generalized and painless nodular subcutaneous lesions. Diagnosis was confirmed based on histopathological examination of skin biopsy which showed cysticerci. Patient's outcome was good under albendazole therapy. [ABSTRACT FROM AUTHOR]

Background: The management of disseminated cysticercosis is unclear and largely considered hazardous. The role of albendazole remains controversial in such patients.Methods: A tertiary care, University hospital-based prospective intervention study was conducted from December 2015 to December 2017. Patients with disseminated cysticercosis, defined as the presence of multiple viable neurocysticerci (≥ 3) in the brain along with involvement of an additional extra site, were included in the study. Patients with cysticercal encephalitis were excluded. A detailed evaluation, including ophthalmoscopy, ocular B scans, ultrasound abdomen, and X-rays were done. Albendazole was administered at a dose of 15 mg/kg/day in 3 cycles of 28 days each. All patients were also given adjuvant corticosteroids and anti-epileptic drugs. Clinical and radiological follow up was carried out at a difference of 3 months between each treatment cycle. For radiological quantification, lesions were counted at 10 pre-specified levels. Statistical analysis was done to estimate the difference in seizure frequency and lesion load.Results: Twenty-nine patients (21 with > 20 lesions; 8 with ≤ 20 lesions) were given albendazole as per the protocol. There was a significant reduction in the occurrence of seizures (P < 0.001) and headache (P < 0.001). A significant reduction in lesion load from baseline to third follow-up was seen in the estimations done at different levels (P < 0.001). No patient developed serious side-effect warranting cessation of therapy.Conclusion: Cyclical use of albendazole appears efficacious in treating disseminated cysticercosis. The method of quantification described may be used in future studies for objective assessment.Trial Registration: ISRCTN11630542; 28th September 2019; Retrospectively registered. [ABSTRACT FROM AUTHOR]

The article presents a case study related to 10-year-old female child presented with fever, irritability, altered sensorium for 20 days and inability to speak. Topics include the patient suffering from tuberculosis (TB) had hypertonia, and the brisk deep tendon reflexes along with left sided upper motor neuron type facial palsy and meningeal irritation.

Introduction and Importance: Cysticercosis is a condition in which humans are infected by the larval form of the pork tapeworm Tenia solium . Cysticercosis in humans is common in the cerebral tissue but rare in the tongue., Case Presentation: Here, the authors report a rare case of a 38-year-old male with neurocysticercosis and cysticercosis of the tongue. The patient presented with a complaint of loss of consciousness for 4-5 min. Local examination of his oral cavity revealed a swelling of ~2×2 cm on the tongue. An MRI of the brain showed various stages of neurocysticercosis involving the neuroparenchyma and tongue. For this, he was started on low-dose prednisolone of 50 mg tapered over 6 weeks and levetiracetam of 500 mg BD continued for his seizure episodes. He is responding well with the medications and is planned to start antiparasitic agent only after the perilesional edema decreases., Clinical Discussion: Cysticercosis may involve the central nervous system, muscle, heart, lungs, peritoneum, eye, and subcutaneous tissue. Oral cavity and perioral involvement by cysticercous larva is rare in humans. Radiologic imaging, serology, and tissue biopsy can be used to confirm a diagnosis of cysticercosis. The most common locations for oral cysticercosis are the tongue, buccal mucosa, lower lip, and upper lip.Only 102 cases of oral cysticercosis have been reported based on a PubMed English-language literature search., Conclusion: Oral cysticercosis is a rare event, and it represents a difficulty in clinical diagnosis. But a patient with a mass in the tongue should be considered as a possible case of cysticercosis especially in endemic regions like Nepal., Competing Interests: The authors declare that they have no financial conflicts of interest with regard to the content of this report., (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)

Pulmonary and cardiac involvement by cysticercosis is extremely rare, and is usually asymptomatic. We report the case of a 19-year-old boy who presented with a history of headache and vomiting and was found to have disseminated cysticercosis with pulmonary and cardiac involvement; the emphasis is on the rare occurrence of pulmonary, cardiac, pancreatic, intraocular, and extradural spinal canal involvement in the same patient. This case demonstrates the extent to which cysticercosis can be disseminated.

Pulmonary and cardiac involvement by cysticercosis is extremely rare, and is usually asymptomatic. We report the case of a 19-year-old boy who presented with a history of headache and vomiting and was found to have disseminated cysticercosis with pulmonary and cardiac involvement; the emphasis is on the rare occurrence of pulmonary, cardiac, pancreatic, intraocular, and extradural spinal canal involvement in the same patient. This case demonstrates the extent to which cysticercosis can be disseminated.

Humans and pigs become the intermediate hosts by ingestion of the eggs excreted in feces by human Taenia solium carriers. Neurocysticercosis is the most common parasitic infection of the brain. A gravid segment of the parasite contains about 40,000 eggs and approximately 50 million people suffer world over with 50,000 annual deaths. Disease modifying treatment options have to be carefully chosen in the selected cases. We report a 14-year-old female child who presented with headache, fever, and blindness of 4 months duration she had bilateral papilledema with no perception of light. Investigations showed the whole brain parenchyma filled with cysts of the trophozoite stage sparing the pons, medulla, and spinal cord. Whole body was filled with sheets of cysticercal lesions in the skin, muscles, eyes, liver, and kidney. Patient was treated with steroids and anti-edema measures. Patient made very good recovery with very mild cognitive and behavioral sequelae. [ABSTRACT FROM AUTHOR]

Disseminated cysticercosis (DCC) is the widespread dissemination of cysticercus cellulosae (larva of pork tapeworm). CNS complications of DCC include encephalitis, obstructive hydrocephalus, raised intracranial pressure, ischemic infarctions, hemorrhage, and rarely subarachnoid hemorrhage. Here, we report a case of young male who developed corpus callosal infarction following cysticercal angitis.

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Cysticercosis is a common tropical disease. One of the uncommon manifestations and a rare complication is its disseminated form (DCC). Neurocysticercosis (NCC) is the common parasitic disease of the central nervous system. Human cysticercosis is caused by the dissemination of the embryo of Taenia solium in the intestine via the hepatoportal system to the tissues and organs of the body. The organs most commonly affected are the subcutaneous tissues, skeletal muscles, lungs, brain, eyes, liver, and occasionally the heart, thyroid, and pancreas. Widespread dissemination of the cysticerci can result in the involvement of almost any organ in the body. We report here a case of a 36-year-old-male with disseminated cysticercosis. He visited our hospital with symptoms of multiple palpable nodules, dementia, and confusion. After the investigations he was diagnosed with disseminated cysticercosis involving the brain, subcutaneous tissues all over the body, and the skeletal muscles. The patient was initially treated with Albendazole in a private hospital, but there was no response. Then he was treated with Praziquantel and steroids. [ABSTRACT FROM AUTHOR]

Abstract: Disseminated cysticercosis is an uncommon presentation of a common disease. Asymptomatic disseminated cysticercosis is rarely reported in literature. Here, we are reporting a case of asymptomatic disseminated cysticercosis incidentally diagnosed in a patient of low backache. Magnetic resonance imaging of lumbosacral spine and neuroimaging done subsequently during the course of evaluation revealed diffuse cysticercosis involving abdominal, paraspinal, pelvic and gluteal muscles along with neurocysticercosis. Such a disseminated cysticercosis was diagnosed incidentally in this patient of low backache with right sciatica and radiculopathy at L5-S1 prolapsed intervertebral disc and was subsequently managed by L5-S1 interlaminar fenestration and discectomy. [Copyright &y& Elsevier]

Disseminated cysticercosis is a rare form of cysticercosis in which the cysticerci spread throughout the body. We describe the case of a seven-year-old child with disseminated cysticercosis. He presented with a one month history of swelling of the whole body, unable to walk for one month and swelling of both eyes for 20 days. After extensive investigation from superficial musculoskeletal ultrasound B-scan of eye, brain computed tomography, brain magnetic resonance imaging (MRI), whole body MRI and pathologic biopsy, the child was diagnosed as having cysticercosis involving the brain, retina and skeletal muscles throughout the whole body. [ABSTRACT FROM AUTHOR]

Cysticercosis is a parasitic disease caused by infestation with the encysted larval stage of the pork tapeworm, Taenia solium. Disseminated cysticercosis is an exceptional expression of this disease characterized by high morbidity due to massive symptomatic parasite burden in the central nervous system, striated muscles, subcutaneous tissues and other organs. Less than 50 such cases have been reported worldwide, and fewer than 10 children. We report on the whole-body MR diagnosis of extensively disseminated cysticercosis in a child. The critical role of whole-body MR as a stand-alone modality in the diagnosis and management of this pleomorphic disease is highlighted. Whole-body MR diagnosis of an infectious disease is unique. [ABSTRACT FROM AUTHOR]

Neurocysticercosis is a common parasitic infection in India presenting usually with seizues, headache, focal neurological deficits. Neurocysticercosis presenting as a psychiatric illness is rare. Disseminated cysticercosis with involvement of central nervous system and head and neck muscles is rare even in endemic areas. We present a case of disseminated cysticercosis, which presented with chronic tension type headache and affective mood disorder. Treatment with cysticidal drugs led to complete remission of psychiatric complaints. In endemic areas history suggestive of mood disorder should not be used as supportive evidence of a primary headache syndome like tension type headche without ruling out secondary causes. Making an early diagnosis can prevent morbidity. [ABSTRACT FROM AUTHOR]

Background: Cysticercosis is an emerging and neglected tropical disease (NTD) that poses a serious public health concern worldwide. Disseminated cysticercosis (DCC) is an uncommon manifestation of cysticercosis, also found in China.Case Presentation: We report three cases of DCC in patients living in China, with different clinical and radiological presentations. All three patients had DCC with active ocular cysticercosis, including one patient with widespread DCC caused by direct ingestion of Taenia solium eggs. The intravitreal cysticercus cyst in this patient was completely extracted entirely by 23-gauge pars plana vitrectomy, and the cyst was oval in shape on the flat mount preparation.Conclusion: The clinical presentation of DCC is highly sophisticated. The diagnosis depended on the typical radiological presentations, biopsy and flat mount preparations of the cyst. [ABSTRACT FROM AUTHOR]

Disseminated cysticercosis is a rare form of cysticercosis in which the cysticerci spread out through the whole body. We report the first case of a 39-year-old Mongolian with disseminated cysticercosis. He visited our hospital with generalized tonic-clonic seizure. After extensive investigation from brain computed tomography (CT), spine magnetic resonance imaging (MRI), whole body MRI and pathologic biopsy, he was diagnosed as having cysticercosis involving the brain, subcutaneous tissue, and skeletal muscles through the whole body. We treated him with the albendazole in which case the followed MRI showed that numbers of cystic lesions were copiously decreased. We report an unsual case of disseminated cysticercosis treated with medical therapy.