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Background: The understanding and description of forbidden decays provides interesting challenges for nuclear theory. These calculations could help to test underlying nuclear models and interpret experimental data. Purpose: Compare a direct measurement of the 138Laβ-decay Q value with the β-decay spectrum end-point energy measured by Quarati et al. using LaBr3 detectors [Appl. Radiat. Isot. 108, 30 (2016)]. Use new precise measurements of the 138Laβ-decay and electron capture (EC) Q values to improve theoretical calculations of the β-decay spectrum and EC probabilities. Method: High-precision Penning trap mass spectrometry was used to measure cyclotron frequency ratios of 138La, 138Ce, and 138Ba ions from which β-decay and EC Q values for 138La were obtained. Results: The 138Laβ-decay and EC Q values were measured to be Qβ=1052.42(41) keV and QEC=1748.41(34) keV, improving the precision compared to the values obtained in the most recent atomic mass evaluation [Wang et al., Chin. Phys. C 41, 030003 (2017)] by an order of magnitude. These results are used for improved calculations of the 138Laβ-decay shape factor and EC probabilities. New determinations for the 138Ce 2EC Q value and the atomic masses of 138La, 138Ce, and 138Ba are also reported. Conclusion: The 138Laβ-decay Q value measured by Quarati et al. is in excellent agreement with our new result, which is an order of magnitude more precise. Uncertainties in the shape factor calculations for 138Laβ decay using our new Q value are reduced by an order of magnitude. Uncertainties in the EC probability ratios are also reduced and show improved agreement with experimental data. [ABSTRACT FROM AUTHOR]

We employ constrained path Auxiliary Field Quantum Monte Carlo (AFQMC) in the pursuit of studying physical nuclear systems using a lattice formalism. Since AFQMC has been widely used in the study of condensed-matter systems such as the Hubbard model, we benchmark our method against published results for both one- and two-dimensional Hubbard model calculations. We then turn our attention to cold atomic and nuclear systems. We use an onsite contact interaction that can be tuned in order to reproduce the known scattering length and effective range of a given interaction. Developing this machinery allows us to extend our calculations to study nuclear systems within a lattice formalism. We perform initial calculations for a range of nuclear systems from two- to few-body neutron systems. This article is part of the theme issue 'The liminal position of Nuclear Physics: from hadrons to neutron stars'.

Lateral flow assays have been widely used for detecting coronavirus disease 2019 (COVID-19). A lateral flow assay consists of a Nitrocellulose (NC) membrane, which must have a specific lateral flow rate for the proteins to react. The wicking rate is conventionally used as a method to assess the lateral flow in membranes. We used multiple regression and artificial neural networks (ANN) to predict the wicking rate of NC membranes based on membrane recipe data. The developed ANN predicted the wicking rate with a mean square error of 0.059, whereas the multiple regression had a square error of 0.503. This research also highlighted the significant impact of the water content on the wicking rate through images obtained from scanning electron microscopy. The findings of this research can cut down the research and development costs of novel NC membranes with a specific wicking rate significantly, as the algorithm can predict the wicking rate based on the membrane recipe., (© 2024. The Author(s).)

Background: Liver transplant is the cure for children with liver failure. Sri Lanka is a lower-middle-income country with a predominant free, state health system. Pediatric liver transplant program in Sri Lanka is still in the budding state where the initial experience of the program is yet to be documented., Methods: A retrospective review was performed including the clinical characteristics of all pediatric liver transplant recipients of Colombo North Centre for Liver Diseases since the inception of the program from June 2020 to May 2023., Results: There were 14 PLT performed in 3 years. The median recipient age and weight were 8 years (6 months-15 years) and 23.3 kg (6.4-49.2), respectively. The majority were boys (64%). All were from low-income backgrounds. Indications for LT were acute liver failure (5/14), decompensated chronic liver disease (5/14), and acute on chronic liver failure (4/14). Underlying liver diseases were Wilson disease (6/14), autoimmune liver disease (3/14), biliary atresia (2/14) and progressive familial intrahepatic cholestasis type 3 (1/14), and unknown etiology (2/14). The majority were living donor liver transplants (86%). Of the living donors, 42% (5/12) were Buddhist priests. There were three immediate deaths and two late deaths. The 3-month survival was 78%, and overall survival was 64%. Living donor transplants carried a higher success rate (92%) compared to diseased donor transplants (0%; 2/2)., Conclusions: Initial experience of pediatric liver transplant program of Sri Lanka is promising despite being established in a free healthcare system amidst the crisis circumstances., (© 2024 Wiley Periodicals LLC.)

Schizophrenia spectrum disorders (SSDs) are associated with significant functional impairments, disability, and low rates of personal recovery, along with tremendous economic costs linked primarily to lost productivity and premature mortality. Efforts to delineate the contributors to disability in SSDs have highlighted prominent roles for a diverse range of symptoms, physical health conditions, substance use disorders, neurobiological changes, and social factors. These findings have provided valuable advances in knowledge and helped define broad patterns of illness and outcomes across SSDs. Unsurprisingly, there have also been conflicting findings for many of these determinants that reflect the heterogeneous population of individuals with SSDs and the challenges of conceptualizing and treating SSDs as a unitary categorical construct. Presently it is not possible to identify the functional course on an individual level that would enable a personalized approach to treatment to alter the individual's functional trajectory and mitigate the ensuing disability they would otherwise experience. To address this ongoing challenge, this study aims to conduct a longitudinal multimodal investigation of a large cohort of individuals with SSDs in order to establish discrete trajectories of personal recovery, disability, and community functioning, as well as the antecedents and predictors of these trajectories. This investigation will also provide the foundation for the co-design and testing of personalized interventions that alter these functional trajectories and improve outcomes for people with SSDs., Competing Interests: I have read the journal’s policy and the authors of this manuscript have the following competing interests: James L. Kennedy is a Member of the Scientific Advisory Board of Myriad Genetics Inc. and Philip Gerretsen is the inventor of the VAGUS insight into psychosis scale which will be used in the PREDICTS Study., (Copyright: © 2023 Agarwal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Arsenic is a metalloid whose presence can be due to natural or anthropological causes. It is considered as a toxic chemical that puts human health at high risk. In this study, we evaluated a novel modified oyster shell (MOS) that was coated with iron (II) sulfate heptahydrate using two different proportions through batch sorption experiments in an arsenic solution and in arsenic-contaminated soils. The arsenic solution was prepared using As(III)-standard solution. The arsenic contaminated soils were extracted from a contaminated site in Cheonan, South Korea, where the average arsenic concentration of the soil was reported as 136.28 mg/kg. Different doses of oyster shell and modified oyster were used to understand the effect of the addition of iron (II) sulfate heptahydrate via sorption batch experiments in solution and sorption tests in soils. The sorption tests were conducted with 50 g of contaminated soil; then, 150 g of soils was used for the pot cultivation tests, and finally, 150 g of contaminated soils was used for column percolation test. Through the experiments, the authors observed a comparable improvement of arsenic stabilization from 10 to 60% with the addition of iron (II) sulfate heptahydrate to oyster shell., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Routine use of the Disease Activity Score-28 (DAS28) to assess the disease activity in rheumatoid arthritis (RA) is limited due to its dependency on laboratory investigations and the complex calculations involved. In contrast, the clinical disease activity index (CDAI) is simple to calculate, which makes the "treat to target" strategy for the management of RA more practical. We aimed to assess the validity of CDAI compared to DAS28 in RA patients in Sri Lanka. A total of 103 newly diagnosed RA patients were recruited, and their disease activity was calculated using DAS 28 and CDAI during the first visit to the clinic (0 months) and re-assessed at 4 and 9 months of follow-up visits. The validity of the CDAI, compared to DAS 28, was evaluated. Patients had a female preponderance (6:1) and a short symptom duration (mean = 6.33 months). Internal consistency reliability of CDAI, as assessed by Cronbach's α test, was 0.868. Convergent validity was assessed by correlation and Kappa statistics. Strong positive correlations were observed between CDAI and DAS 28 at the baseline (0 months), 4 and 9 months of evaluation (Spearman's r = 0.935, 0.935, 0.910, respectively). Moderate-good inter-rater agreements between the DAS-28 and CDAI were observed (Weighted kappa of 0.660, 0.519, and 0.741 at 0, 4, and 9 months respectively). Discriminant validity, as assessed by ROC curves at 0, 4th, and 9th months of the evaluation, showed the area under the curve (AUC) of 0.958, 0.979, and 0.910, respectively. The suggested cut-off points for different CDAI disease activity categories according to ROC curves were ≤ 4 (Remission), > 4 to ≤ 6 (low), > 6 to ≤ 18 (moderate), > 18 (high). These findings indicate that the CDAI has good concordance with DAS 28 in assessing the disease activity in RA patients, in this study sample., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2022 Dissanayake et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Single-use disposable facemasks have been used as a preventive measure against the ongoing COVID-19 pandemic. However, many researchers have found evidence that these facemasks are being dumped into lakes, rivers, and open garbage dumps. Facemasks have the potential of releasing microplastic fibers into the environment; a phenomenon that has been poorly investigated. Moreover, microplastic fibers composed of plastics have the potential of affecting the flora and fauna of many ecosystems. In this preliminary study, we investigate how many microplastic fibers had been released to the water by KF-AD, KF94, surgical, and FFP1 standard facemasks, which are the most widely available facemask standards in South Korea. The waterbody in our research was mechanically agitated for 24, 48, and 72 h. Findings showed that most of the layers of facemasks are composed of polypropylene. The surgical and KF94 standard facemasks released the highest number of microplastic fibers. Furthermore, under our research conditions, a single facemask can release at least 47 microplastic fibers per day (e.g., KF-AD standard mask), which can lead to the release of at least 1381 million microplastic fibers per day in total in South Korea if 70% of the urban population uses a single mask every day. Moreover, the released microplastic fibers significantly increased when the agitation time extended from 24 to 48 h. This finding suggests that the number of released microplastic fibers is likely to increase drastically.

Rainwater harvesting (RWH) is a sustainable solution for curbing existing urban water crises. Many countries have implemented various design guidelines for RWH systems, but water quality issues persist, especially with respect to particulate matter and soluble contaminants entering the RWH system after a prolonged dry period. A first-flush unit in an RWH system can partially manage this sudden influx of pollutants, provided that rainfall conditions are favorable for its optimal operation. Therefore, a significant proportion of these pollutants reach the storage tank. The most common single storage tank RWH systems accumulate particulate matter, and allow soluble and particulate contaminants to reach the outlet quickly at undesirably high concentrations. To overcome these issues pertaining to single tank systems, multiple tank systems with similar volumes have been implemented globally. However, limited research has been conducted to assess the effect of the number of tanks on harvested water quality under a sudden pollutant input. Hence, the authors have investigated the effect of the number of tanks on particulate matter distribution in multi-tank systems, and observed that more than 60% of the particle mass input was retained in the first tank. By increasing the number of tanks, the particle mass reaching the final tank becomes constant despite changes in the flowrate and influx particle mass. Furthermore, a soluble contaminant entering a multi-tank system was observed to reside within the system for a prolonged time by approximately a factor of two, which is favorable for developing a response strategy. It is recommended by the authors that at least three tanks should be used to gain the benefits of a multiple-tank RWH system., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.)

Low-cost absorbent materials have elicited the attention of researchers as binders for the stabilisation/solidification technique. As, there is a no comprehensive study, the authors of this paper investigated the performance of Oyster shell powder (OS), zeolite (Z), and red mud (RM) in stabilising heavy metals in three types of heavy metal-contaminated soils by using toxicity characteristic leaching procedure (TCLP). Samples were collected from surroundings of an abandoned metal mine site and from military service zone. Furthermore, a Pb-contaminated soil was artificially prepared to evaluate each binder (100× regulatory level for Pb). OS bound approximately 82% of Pb and 78% of Cu in real cases scenario. While Z was highly effective in stabilizing Pb in highly polluted artificial soil (>50% of Pb) at lower dosages than OS and RM, it was not effective in stabilising those metals in the soils obtained from the contaminated sites. RM did not perform consistently stabilising toxic metals in soils from contaminated sites, but it demonstrated a remarkable Pb-immobilisation under dosages over than 5% in the artificial soil. Further, authors observed that OS removal efficiency reached up to 94% after 10 days. The results suggest that OS is the best low-cost adsorbent material to stabilize soils contaminated with toxic metals considered in the study.

The imposition and lifting of non-pharmaceutical interventions (NPIs) to avert the COVID-19 pandemic have gained popularity worldwide and will continue to be enforced until herd immunity is achieved. We developed a linear regression model to ascertain the nexus between the time-varying reproduction number averaged over a time window of six days (R ts ) and seven NPIs: contact tracing, quarantine efforts, social distancing and health checks, hand hygiene, wearing of facemasks, lockdown and isolation, and health-related supports. Our analysis suggests that the second wave that emerged in Sri Lanka in early October 2020 continued despite numerous NPIs. The model indicates that the most effective single NPI was lockdown and isolation. Conversely, the least effective individual NPIs were hand hygiene and wearing of facemasks. The model also demonstrates that to mitigate the second wave to a satisfactory level (R ts <1), the best single NPI was the contact tracing with stringent imposition (% of improvement of R ts was 69.43 against the base case). By contrast, the best combination of two NPIs was the lockdown & isolation with health-related supports (% of improvement was 31.92 against the base case). As such, many health authorities worldwide can use this model to successfully strategize the imposition and lifting of NPIs for averting the COVID-19 pandemic., Competing Interests: The authors declare that they have no known conflict of interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2021 The Authors.)

Meethotamulla open dump (MOD) of Sri Lanka that has received about 290,000 metric tons of mixed MSW annually collapsed on 14th April 2017 with massive devastation. An integrated approach was attempted to control further collapse with the deployment of drone-assisted and stand-alone instrumentation. The collapsed dump was analyzed for attributes, including contours, heights, wetness, temperature levels, tension cracks, landfill gases, fire, explosion, and asphyxiation hazards with 24-h surveillance after one day of the collapse. The mode of MOD failure was implicated to be deep-seated (rotational) slope failure. A short-term plan, consisting of 12 activities was prepared and successfully implemented. The activities of the short-term plan were carried out at the dumpsite until the water level fluctuations <5 cm, inundation of the toe area receded completely, the horizontal displacement of surface markers <20 mm, lower explosive levels of CH 4 and CO less than 5 and 12%, respectively, O 2 level improved up to 21%, and temperature variation of the collapsed face <2 °C. The short-term plan was halted when the factor of safety for slope failure of the critical face improved from 0.807 to 1.286 ensuring no signs of a subsequent collapse of the MOD. An early warning system was established in the case of an imminent collapse. This integrated approach, to our knowledge, is the first study instituted, and this holistic management effort could be easily replicated to avoid disasters from slope failures of landfills or open dumps that may occur elsewhere., (Copyright © 2019 Elsevier Ltd. All rights reserved.)

JS-2 is a novel gene located at 5p15.2 and originally detected in primary oesophageal cancer. There is no study on the role of JS-2 in colorectal cancer. The aim of this study is to determine the gene copy number and expression of JS-2 in a large cohort of patients with colorectal tumours and correlate these to the clinicopathological features of the cancer patients. We evaluated the DNA copy number and mRNA expression of JS-2 in 176 colorectal tissues (116 adenocarcinomas, 30 adenomas and 30 non-neoplastic tissues) using real-time polymerase chain reaction. JS-2 expression was also evaluated in two colorectal cancer cell lines and a benign colorectal cell line. JS-2 amplification was noted in 35% of the colorectal adenocarcinomas. Significant differences in relative expression levels for JS-2 mRNA between different colorectal tissues were noted (p = 0.05). Distal colorectal adenocarcinoma had significantly higher copy number than proximal adenocarcinoma (p = 0.005). The relative expression level of JS-2 was different between colonic and rectal adenocarcinoma (p = 0.007). Mucinous adenocarcinoma showed higher JS-2 expression than non-mucinous adenocarcinoma (p = 0.02). Early T-stage cancers appear to have higher JS-2 copy number and lower expression of JS-2 mRNA than later stage cancers (p = 0.001 and 0.03 respectively). Colorectal cancer cell lines showed lower expression of JS-2 than the benign colorectal cell line. JS-2 copy number change and expression were shown for the first time to be altered in the carcinogenesis of colorectal cancer. In addition, genetic alteration of JS-2 was found to be related to location, pathological subtypes and staging of colorectal cancer., (Copyright © 2011 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.)