1. A large multi-pathogen waterborne community outbreak linked to faecal contamination of a groundwater system, France, 2000
- Author
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B. Ladeuil, Fabienne Bon, M. Cournot, Francis Mégraud, P. Le Cann, Anne Gallay, H de Valk, Jean-Claude Desenclos, C Castor, C. Hemery, De´partement Maladies Infectieuses, Unite´ Infections Ente´riques, Alimentaires et Zoonoses ( INVS ), Institut de Veille Sanitaire (INVS), Cellule Inter Régionale de l'Epidémiologie d'Intervention du Sud Ouest ( CIRE Sud Ouest ), Direction Départementale de l'Agriculture et de la Forêt du Lot, Laboratoire Interactions Muqueuses Agents Transmissibles ( LIMA ), Université de Bourgogne ( UB ), Centre National de Référence des Campylobacters et Hélicobacters ( CNR Campylobacters et Hélicobacters ), CHU Bordeaux [Bordeaux], Laboratoire de Microbiologie, IFREMER, Institut Français de Recherche pour l'Exploitation de la Mer ( IFREMER ), De´partement Maladies Infectieuses, Unite´ Infections Ente´riques, Alimentaires et Zoonoses (INVS), Cellule Inter Régionale de l'Epidémiologie d'Intervention du Sud Ouest (CIRE Sud Ouest), Laboratoire Interactions Muqueuses Agents Transmissibles (LIMA), Université de Bourgogne (UB), Centre National de Référence des Campylobacters et Hélicobacters (CNR Campylobacters et Hélicobacters), and Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)
- Subjects
Rotavirus ,MESH : Retrospective Studies ,Epidemiology ,MESH : Aged ,Disease Outbreaks ,Feces ,0302 clinical medicine ,MESH : Child ,Surveys and Questionnaires ,MESH: Child ,Campylobacter Infections ,Medicine ,Child ,MESH: Water Supply ,Caliciviridae Infections ,0303 health sciences ,MESH: Middle Aged ,MESH: Feces ,General Medicine ,MESH: Rotavirus ,3. Good health ,MESH : Gastroenteritis ,[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology ,Child, Preschool ,gastroenteritis ,Microbiology (medical) ,MESH: Norovirus ,medicine.medical_specialty ,MESH : Campylobacter Infections ,norovirus ,MESH : Cohort Studies ,Microbiology ,03 medical and health sciences ,Water Supply ,MESH : Adolescent ,Humans ,MESH : Middle Aged ,MESH : Disease Outbreaks ,Aged ,Retrospective Studies ,MESH: Adolescent ,MESH: Humans ,030306 microbiology ,MESH: Questionnaires ,MESH : Water Microbiology ,MESH: Child, Preschool ,MESH : Humans ,Outbreak ,MESH: Adult ,MESH: Retrospective Studies ,MESH: Campylobacter coli ,Waterborne outbreak ,MESH: Gastroenteritis ,MESH: Water Microbiology ,MESH : Campylobacter coli ,rotavirus ,Campylobacter coli ,MESH : Child, Preschool ,medicine.disease_cause ,Cohort Studies ,[ SDV.MP ] Life Sciences [q-bio]/Microbiology and Parasitology ,waterborne outbreak ,030212 general & internal medicine ,MESH: Disease Outbreaks ,MESH: Cohort Studies ,MESH: Caliciviridae Infections ,MESH: Aged ,biology ,Campylobacter ,MESH : Questionnaires ,Middle Aged ,MESH: Rotavirus Infections ,MESH : Adult ,Gastroenteritis ,Infectious Diseases ,epidemiology ,France ,MESH : Caliciviridae Infections ,Water Microbiology ,Adult ,Adolescent ,MESH : Rotavirus ,Rotavirus Infections ,MESH: Campylobacter Infections ,MESH : Water Supply ,Environmental health ,MESH : Rotavirus Infections ,MESH : France ,business.industry ,MESH : Norovirus ,Norovirus ,Retrospective cohort study ,MESH : Feces ,biology.organism_classification ,MESH: France ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,business - Abstract
International audience; A large waterborne outbreak of infection that occurred during August 2000 in a local community in France was investigated initially via a rapid survey of visits to local physicians. A retrospective cohort study was then conducted on a random cluster sample of residents. Of 709 residents interviewed, 202 (28.5%) were definite cases (at least three liquid stools/day or vomiting) and 62 (8.7%) were probable cases (less than three liquid stools/day or abdominal pain). Those who had drunk tap water had a three-fold increased risk for illness (95% CI 2.4-4.0). The risk increased with the amount of water consumed (chi-square trend: p < 0.0001). Bacteriological analyses of stools were performed for 35 patients and virological analyses for 24 patients. Campylobacter coli, group A rotavirus and norovirus were detected in 31.5%, 71.0% and 21% of samples, respectively. An extensive environmental investigation concluded that a groundwater source to this community had probably been contaminated by agricultural run-off, and a failure in the chlorination system was identified. This is the first documented waterborne outbreak of infection involving human C. coli infections. A better understanding of the factors influencing campylobacter transmission between hosts is required.
- Published
- 2006