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OBJECTIVE In this study, we tested direct pathways from trauma exposure to trauma symptomatology and risky and self-destructive behavior and indirect pathways through two cognitive and affective mechanisms: (a) world assumptions and (b) emotion dysregulation. METHOD A sample of 270 undergraduate students with an average age of 20.02 years participated in the study (204 women, 65 men, and one participant choosing not to disclose). Participants completed self-report measures assessing trauma exposure, trauma symptoms, emotion dysregulation, world assumptions, and lifetime and past-month engagement in any of 38 risky and self-destructive behaviors. RESULTS The direct path from trauma exposure to trauma symptoms was significant, and so was the indirect effect of self-worth assumptions on this association. The indirect pathway between trauma symptoms and risky and self-destructive behavior in the past month was significant through difficulties with impulse control when distressed. Trauma symptoms had an indirect effect on the association between trauma exposure and lifetime and past-month engagement in risky and self-destructive behavior, while the direct pathway from trauma exposure to lifetime engagement remained significant. CONCLUSION We offer theoretically and empirically supported integrative pathways that explicate some aspects of trauma exposure's negative sequelae with potential areas for intervention. Clinical Impact Statement: Trauma exposure is widespread and is associated with negative views about oneself and the world and with difficulties in managing one's emotions, which in part is associated with individuals' risk for developing psychopathology and engaging in risky and self-destructive behaviors. The findings inform optimal time for intervention and prevention efforts targeting trauma exposure. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Background: Hand tremor is one of the consequences of MS disease degrading quality of patient’s life. Recently DBS is used as a prominent treatment to reduce this effect. Evaluation of this approach has significant importance because of the prevalence rate of disease.Objective: The purpose of this study was the nonlinear analysis of tremor signal in order to evaluate the quantitative effect of DBS on reducing MS tremor and differentiating between them using pattern recognition algorithms.Material and Methods:In this paper, nine features were extracted from the tremor signal. Through statistical analysis, the significance level of each feature was examined. Finally, tremor signals were categorized by SVM, weighted KNN and NN classifiers. The performance of methods was compared with an ROC graph.Results:The results have demonstrated that dominant frequency, maximum amplitude and energy of the first IMF, deviation of the direct path, sample entropy and fuzzy entropy have the potential to create a significant difference between the tremor signals. The classification accuracy rate of tremor signals in three groups for Weighted KNN, NN and SVM with Gaussian and Quadratic kernels resulted in 95.1%, 93.2%, 91.3% and 88.3%, respectively.conclusion: Generally, nonlinear and nonstationary analyses have a high potential for a quantitative and objective measure of MS tremor. Weighted KNN has shown the best performance of classification with the accuracy of more than 95%. It has been indicated that DBS has a positive influence on reducing the MS tremor. Therefore, DBS can be used in the objective improvement of tremor in MS patients.

Objective To assess whether pandemic-related restrictions with video-based interviewing increased geographic clustering of urology applicants matching at a residency program near where they were raised or attended medical school. Materials and Methods We utilized publicly available data from the urology match to compare dispersal patterns between applicants matching during the COVID-19 application cycle (2021) and those matching in the 5 prior application cycles (2016-2020). Variables included home state, undergraduate institution, medical school, and residency. Latitudes and longitudes were obtained for each institution and home state. The primary endpoint was distance (miles, as the most direct path) between medical school and residency program. We also assessed dispersal patterns by American Urological Association section. Results Of the 1965 applicants matching to a urology program between 2016 and 2021, medical school was identified for 1956 (99.7%) applicants, undergraduate program for 1551 (79%) applicants, and home state for 1351 (69%) applicants. Comparing the COVID-19 application cycle to the 5 prior application cycles, there was no significant difference in the median distance between medical school and residency, undergraduate university and residency, or home state and residency. Similarly, there was no significant difference in the proportion of applicants matching at their home institution, matching from medical schools without a home urology program, matching from medical schools with a historically low volume of urology applicants ( Conclusion Virtual interviewing and the loss of in-person clinical rotations did not significantly alter dispersal patterns or hamper an applicant's ability to match at program outside their geographic region.

Wireless sensing received a great amount of attention in recent years and various wireless technologies have been exploited for sensing, including WiFi [1], RFID [2], ultrasound [3], 60 GHz mmWave [4] and visible light [5]. The key advantage of wireless sensing over traditional sensing is that the target does not need to be equipped with any sensor(s) and the wireless signal itself is being used for sensing. Exciting new applications have been enabled, such as passive localization [6] and contactless human activity sensing [7]. While promising in many aspects, one key limitation of current wireless sensing techniques is the very small sensing range. This is because while both direct path and reflection path signals are used for communication, only the weak target-reflection signals can be used for sensing. Take Wi-Fi as an example: the communication range can reach 20 to 50 meters indoors but its sensing range is merely 4 to 8 meters. This small range further limits the through-wall sensing capability of Wi-Fi. On the other hand, many applications do require long-range and through-wall sensing capability. In a fire rescue scenario, the sensing device cannot be placed close to the building, and the long-range through-wall sensing capabilities are critical for detecting people deep inside the building. Table I summarizes the sensing range of existing wireless technologies. We can see that long-range through-wall sensing is still missing with wireless sensing.

In recent years, advancements in photocatalysis have allowed for a plethora of chemical transformations under milder conditions. Many of these photochemical reactions utilize hydrogen atom transfer processes to obtain desired products. Hydrogen atom transfer processes can follow one of two unique pathways: the first, a direct path and the second, an indirect path. In this paper, we highlight the ability of eosin Y to act as a direct hydrogen atom transfer catalyst from both synthetic and computational chemistry perspectives.

Extracurricular involvement in the school-age years has widespread potential benefits for children’s subsequent socioemotional development, especially for low-income youth. However, there is a dearth of research on interventions aimed at increasing school-age extracurricular involvement in low-income youth. Thus, the present study aimed to test the collateral effect of a brief, family-focused intervention for low-income families, the Family Check-Up, on children’s school-age extracurricular involvement via improvements in maternal Positive Behavior Support in early childhood. The sample (n = 630, 50% female, 50% White, 28% Black/African American) represented a subsample of families from the Early Steps Multisite Study. At age 2, families were randomly assigned to the Family Check-Up or Women, Infants, and Children Nutritional Supplement Services as usual. Mother-child dyads participated in observed interaction tasks at child ages 2 and 3 that were subsequently coded to assess positive behavior support. Primary caregivers reported on children’s school-age extracurricular involvement at ages 7.5, 8.5, and 9.5. Results indicated that although there was not a direct path between intervention status and children’s school-age extracurricular involvement, a significant indirect path emerged from intervention group to changes in positive behavior support between ages 2 to 3 to children’s school-age extracurricular involvement. The results are discussed in terms of implications for designing preventive interventions in early childhood that promote extracurricular involvement at school-age, particularly for children at risk for maladaptive outcomes.

Background Work stress has been proved to be linked to depression, and both can decrease general trust. Likewise, OXTR gene is currently the gene that is most closely associated with trust. However, few empirical studies have explored the significant role of gene–environment interactions on general trust. In this study, we explored the mediating role of depression in the relationship between work stress and general trust, and the moderating role of the OXTR rs 53576 in the mediation model. Methods 364 healthy Han Chinese faculties were recruited from one university in Beijing. Work stress, depression, and general trust were assessed using the House and Rizzo's Work Stress Scale, Self-Rating Depression Scale (SDS), and the General Trust Questionnaire, respectively. Blood samples were collected for OXTR rs53576 genotyping. Results Depression mediated the relationship between work stress and general trust. In the mediation model, OXTR rs53576 could only moderated the direct path from work stress to general trust. For AA and GA individuals, depression completely mediated the relationship between work stress and general trust. For GG individuals, depression partly mediated the relationship between work stress and general trust. Limitations This study used a cross-sectional design, only considered Han Chinese faculties, and the role of other genes should be explored. Conclusions Depression has a mediating effect between work stress and general trust. The general trust levels of GG genotype individuals are more prone to be affected by work stress than AA and GA individuals.

Objective This study aimed to analyze the effect of perceived value on patient loyalty, both directly and indirectly through the patient satisfaction variable. Methods This research is analytic observational with a cross-sectional design. Among 187 patients at the outpatient installation's Hasanuddin University Hospital was selected through purposive sampling technique with the inclusion criteria such as non-insurance patient at least twice visits on their own, not because doctor's preference. Path analyses used to know the level of magnitude and significance of a causal relationship. Results The indirect path's coefficient value 0.348 is greater the direct path's coefficient which is only 0.041. It was determined that perceived value affected patient loyalty indirectly through patient satisfaction. Regression shows that the satisfaction variable 12.589 times more influential on loyalty than the perceived value which is only 2.344 times. Conclusion To increase loyalty, patient need to be satisfied firstly, especially those related to aspects of doctor services.

This study examined if the effect of family functioning on preschoolers’ school readiness can be mediated by mothers’ affective parenting and preschoolers’ self-regulation in the year before children enter elementary school. This study analyzed the 7th year data of panel study of Korean children collected by the Korean Institute of Child Care and Education. Statistical analysis included 1,513 pairs of 6-year-old children and mothers. Descriptive statistics analysis, correlation analysis, structural equation modeling, and bootstrapping analysis were conducted using SPSS 22 and Amos 20. The primary findings were as follows. First, the sub-factors of preschoolers’ school readiness composed of children’s social and emotional development, approach to learning, cognitive development and general knowledge, and communication were positively correlated with family functioning, mothers’ affective parenting, and preschoolers’ self-regulation. Second, the result of structural equation modeling showed that the indirect paths from family functioning to preschoolers’ school readiness through mothers’ affective parenting and preschoolers’ self-regulation were significant, while the direct path was insignificant. Third, bootstrapping analysis showed that mothers’ affective parenting and preschoolers’ self-regulation fully mediated the relationship between family functioning and preschoolers’ self-regulation. The findings provide the grounds for families and parents with preschool aged children to implement effective support practices to maintain a functional family system that can promote preschoolers’ school readiness.

Purpose Several studies have explored factors causing depression in cancer survivors, including perceived physical symptoms. Another critical factor in the depression symptomatology of cancer survivors is activity restriction (AR). We investigated how AR mediate the effects of perceived pain and fatigue on depression in cancer survivors. Methods Cancer survivors (n = 61; mean age 56.16 years) that were recruited through cancer support groups in Japan participated in this study. Participants completed a battery of questionnaires comprising demographic and clinical information, the Pain Catastrophizing Scale, the Cancer Fatigue Scale, the Activity Restriction Scale for Cancer Patients, and the Hospital Anxiety and Depression Scale. Results Mediation analysis indicated that AR partially mediates the effect of pain on depression. Direct paths from pain to AR, AR to depression, and pain to depression were significant (P

The longitudinal joints on adjacent precast, prestressed box beams used in bridge construction are vulnerable to cracking. These cracks provide a direct path for water and deleterious agents to enter the structural system, causing corrosion of the embedded steel bars and tendons. To avoid significant maintenance costs, safety concerns, or both, an innovative longitudinal joint between two adjacent box beams was designed in the current study. This joint is 6½ in. wide with roughened surfaces, filled with shrinkage compensating concrete and reinforced by steel bars. The joint was evaluated on a small-scale basis and satisfactory performance was obtained in resisting early-age cracks. In the current paper, the joint design is further evaluated through experiments on a 31 ft long specimen during the joint’s early age, and when it is subjected to multiple levels of cyclic loads. A finite element (FE) model that is capable of simulating the early-age concrete hardening was also developed and validated against the experimental data. The early-age, time-dependent stress development in the joint and at the interface of the joint and box beam was investigated using the FE model. Based on the results of laboratory tests and FE simulations, the innovative joint was found to remain crack free without the utilization of a shear key or transverse post-tensioning. The “compression-dominate” joint created by the expansive joint material and transverse reinforcing bars across the interface is expected to address the issues associated with early age, while ensuring the long-term durability and performance of box-beam bridges.

The article discusses the essence of STEM-education, which is based not on theory, but on the ability to use their knowledge in practice. When STEM-education, the usual form of teaching for us is changing, when the lesson is built around a teacher. According to the STEM methodology, the focus is on the practical problem. Possible ways to implement the idea of STEM education are integrated lessons of different types, design and research activities. The basis of STEM-education is person-oriented learning. The importance of STEM-education in working with students with special educational needs is determined. In particular, STEMeducation provides special children with the availability, diversity and dynamism of learning, teamwork, the ability to apply their knowledge in real life, the development of critical thinking, self-confidence, the direct path from education to careers. It was found that it is extremely necessary, when introducing STEM-education, to develop in students «meikerskie» abilities that contribute to the smooth reincarnation of the ideas of the latest technologies. One of the «maker» types in elementary school can be an ancient form of art - origami. Origami classes have a good effect on special children and contain a huge correctional potential.

Global environmental change challenges humanity because of its broad scale, long-lasting, and potentially irreversible consequences. Key to an effective response is to use an appropriate scientific lens to peer through the mist of uncertainty that threatens timely and appropriate decisions surrounding these complex issues. Identifying such corridors of clarity could help understanding critical phenomena or causal pathways sufficiently well to justify taking policy action. To this end, we suggest four principles: Follow the strongest and most direct path between policy decisions on outcomes, focus on finding sufficient evidence for policy purpose, prioritize no-regrets policies by avoiding options with controversial, uncertain, or immeasurable benefits, aim for getting the big picture roughly right rather than focusing on details.

Summary We rapidly classify odors as pleasant or aversive, but the brain circuits underlying how odors motivate approach and avoidance responses are largely unknown. New research describes a direct path from the olfactory bulb to ventral striatum driving odor-mediated reward.

Intimate Partner Violence (IPV) is a major public health issue, including during pregnancy where it poses a serious risk to the woman’s health. Influenza-Like Illness (ILI) also causes significant morbidity for women during pregnancy. It may be possible that ILI in pregnancy is associated with IPV, and that depression and trauma history play a role in the connection. 524 Australia-born women and 578 refugee-background women. Baseline participants were randomly recruited and interviewed from antenatal clinics between January 2015 and March 2016, and they were reinterviewed six months post-partum. Bivariate and path analysis were used to assess links between IPV, depression and ILI. One in 10 women (10%, 111 out of 1102) reported ILI during their pregnancy period and this rate was significantly (p &lt, 0.001) higher for women born in conflict-affected countries (13%, 76 out of 578) as compared to Australian-born women (7%, 35 out of 524). In both groups, Time 1 traumatic events, IPV and depression symptoms were significantly associated with ILI at Time 2. A significant association between IPV at Time 1 and ILI at Time 2 was fully mediated by depression symptoms at Time 1 (Beta = 0.36 p &lt, 0.001). A significant direct path was shown from depression symptoms to ILI (Beta = 0.26, p &lt, 0.001). Regardless of migration history, pregnant women who have experienced IPV and depression are more likely to report influenza-like symptoms in pregnancy. This may suggest that trauma and depression negatively affect immunity, although it could also indicate a connection between depressive symptoms and physical experiences of ILI.

Localization is important for a large number of Internet of Things (IoT) endpoint devices connected by LoRaWAN. Due to the bandwidth limitations of LoRaWAN, existing localization methods without specialized hardware (e.g., GPS) produce poor performance. To increase the localization accuracy, we propose a super-resolution localization method, called Seirios, which features a novel algorithm to synchronize multiple non-overlapped communication channels by exploiting the unique features of the radio physical layer to increase the overall bandwidth. By exploiting both the original and the conjugate of the physical layer, Seirios can resolve the direct path from multiple reflectors in both indoor and outdoor environments. We design a Seirios prototype and evaluate its performance in an outdoor area of 100 m $\times$ 60 m, and an indoor area of 25 m $\times$ 15 m, which shows that Seirios can achieve a median error of 4.4 m outdoors (80% samples < 6.4 m), and 2.4 m indoors (80% samples < 6.1 m), respectively. The results show that Seirios produces 42% less localization error than the baseline approach. Our evaluation also shows that, different to previous studies in Wi-Fi localization systems that have wider bandwidth, time-of-fight (ToF) estimation is less effective for LoRaWAN localization systems with narrowband radio signals., MOBICOM 2021

Reconfigurable Intelligent Surface (RIS) is one of the latest technologies in bringing a certain amount of control to the rather unpredictable and uncontrollable wireless channel. In this paper, RIS is introduced in a bidirectional system with two source nodes and a Decode and Forward (DF) relay node. It is assumed that there is no direct path between the source nodes. The relay node receives information from source nodes simultaneously. The Physical Layer Network Coding (PLNC) is applied at the relay node to assist in the exchange of information between the source nodes. Analytical expressions are derived for the average probability of errors at the source nodes and relay node of the proposed RIS-assisted bidirectional relay system. The Bit Error Rate (BER) performance is analyzed using both simulation and analytical forms. It is observed that RIS-assisted PLNC based bidirectional relay system performs better than the conventional PLNC based bidirectional system.