Search

Your search keyword '"Ding, Wen-ya"' showing total 13 results
Start Over Author "Ding, Wen-ya"
13 results on '"Ding, Wen-ya"'

3. The Active Ingredients Identification and Antidiarrheal Mechanism Analysis of Plantago asiatica L. Superfine Powder

Author

Dong, Chun-Liu, primary, Qin, Yue, additional, Ma, Jin-Xin, additional, Cui, Wen-Qiang, additional, Chen, Xing-Ru, additional, Hou, Li-Ya, additional, Chen, Xue-Ying, additional, God’spower, Bello-Onaghise, additional, Eliphaz, Nsabimana, additional, Qin, Jun-Jie, additional, Guo, Wen-Xin, additional, Ding, Wen-Ya, additional, and Li, Yan-Hua, additional

Published
2021
Full Text
View/download PDF

4. CD‐g‐CS nanoparticles for enhanced antibiotic treatment of Staphylococcus xylosus infection.

Author

Zheng, Si‐Di, Zhang, Zhi‐Yun, Ma, Jin‐Xin, Qu, Qian‐Wei, God'spowe, Bello‐Onaghise, Qin, Yue, Chen, Xue‐Ying, Li, LU, Zhou, Dong‐Fang, Ding, Wen‐Ya, and Li, Yan‐Hua

Subjects
STAPHYLOCOCCAL diseases, ANTIBIOTICS, NANOPARTICLES, TREATMENT effectiveness, MASTITIS, THERAPEUTICS
Abstract

Summary: Staphylococcus xylosus (S. xylosus)‐induced cow mastitis is an extremely serious clinical problem. However, antibiotic therapy does not successfully treat S. xylosus infection because these bacteria possess a strong biofilm formation ability, which significantly reduces the efficacy of antibiotic treatments. In this study, we developed ceftiofur‐loaded chitosan grafted with β‐cyclodextrins (CD‐g‐CS) nanoparticles (CT‐NPs) using host–guest interaction. These positively charged nanoparticles improved bacterial internalization, thereby significantly improving the effectiveness of antibacterial treatments for planktonic S. xylosus. Moreover, CT‐NPs effectively inhibited biofilm formation and eradicated mature biofilms. After mammary injection in a murine model of S. xylosus‐induced mastitis, CT‐NPs significantly reduced bacterial burden and alleviated inflammation, thereby achieving optimized therapeutic efficiency for S. xylosus infection. In conclusion, this treatment strategy could improve the efficiency of antibiotic therapeutics and shows great potential in the treatment of S. xylosus infections. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

5. MOESM1 of Transcriptomic analysis reveals flavonoid biosynthesis of Syringa oblata Lindl. in response to different light intensity

Author

Liu, Yan-Yan, Xing-Ru Chen, Wang, Jin-Peng, Cui, Wen-Qiang, Xing, Xiao-Xu, Chen, Xue-Ying, Ding, Wen-Ya, Bello-Onaghise God’Spower, Nsabimana Eliphaz, Meng-Qing Sun, and Li, Yan-Hua

Abstract

Additional file 1: Figure S1. Genes with significant differential expression in Syringa oblata Lindl. Figure S2. Volcano diagram of differentially expressed Unigenes between two groups in Syringa oblata Lindl. Figure S3. GO enrichment analysis of differentially expressed Unigenes in Syringa oblata Lindl. Table S1. Air pollution index for May to October in 2017. Table S2 Fluorescence quantitative real-time PCR primer sequence.

Published
2019
Full Text
View/download PDF

7. Process optimization of Syringa oblata Lindl. by response surface methodology and its effect on Staphylococcus xylosus biofilm

Author

Chen, Xing-Ru, primary, Liu, Yan-Yan, additional, Zhou, Yong-Hui, additional, Xing, Xiao-Xu, additional, Qu, Qian-Wei, additional, Chen, Xue-Ying, additional, Ding, Wen-Ya, additional, Cheng, Guang-Long, additional, Wei, Ai-Juan, additional, Feng, Xi-Wen, additional, God'spower, Bello-Onaghise, additional, Eliphaz, Nsabimana, additional, and Li, Yan-Hua, additional

Published
2019
Full Text
View/download PDF

13. [Research progress on liposome and nanomicelle targeted drug delivery system across blood-brain barrier].

Author

Yang X, Zou LH, Ding WY, Zhang ZB, Chen JQ, Li JL, Feng HL, Li YY, Tang L, and Feng JF

Subjects
Humans, Liposomes, Micelles, Drug Delivery Systems, Biological Transport, Brain, Blood-Brain Barrier, Brain Diseases
Abstract

The blood-brain barrier(BBB), a protective barrier between brain tissues and brain capillaries, can prevent drugs from entering the brain tissues to exert the effect, which greatly increases the difficulty in treating brain diseases. The drug delivery system across the BBB can allow efficient drug delivery across the BBB by virtue of carriers and formulations, thereby enhancing the therapeutic effect of drugs on brain tissue diseases. Liposomes and micelles have been extensively studied with advances in the targeted therapy across the BBB for the brain due to their unique structures and drug delivery advantages. This study summarized the research status of liposome and micelle drug delivery systems across the BBB based on the literature in recent years and analyzed their application advantages and mechanism in terms of trans-BBB capability, targeting, and safety. Moreover, the problems and possible countermeasures in the research on trans-BBB liposomes and micelles were discussed according to the current clinical translation, which may provide refe-rences and ideas for the development of trans-BBB targeted nano-drugs.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results