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312 results on '"Dimitriadis, Georgios K"'

2. Bariatric surgery for spontaneous ovulation in women living with polycystic ovary syndrome: the BAMBINI multicentre, open-label, randomised controlled trial

Author

Samarasinghe, Suhaniya N S, Leca, Bianca, Alabdulkader, Shahd, Dimitriadis, Georgios K, Davasgaium, Allan, Thadani, Puja, Parry, Kate, Luli, Migena, O'Donnell, Karen, Johnson, Brett, Abbara, Ali, Seyfried, Florian, Morman, Rachel, Ahmed, Ahmed R, Hakky, Sherif, Tsironis, Christos, Purkayastha, Sanjay, le Roux, Carel W, Franks, Stephen, Menon, Vinod, Randeva, Harpal, and Miras, Alexander D

Published
2024
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4. Efficacy and safety of baricitinib or ravulizumab in adult patients with severe COVID-19 (TACTIC-R): a randomised, parallel-arm, open-label, phase 4 trial

Author

Hall, Frances C, Cheriyan, Joseph, Cope, Andrew P, Galloway, James, Wilkinson, Ian, Bond, Simon, Norton, Sam, Banham-Hall, Edward, Bayes, Hannah, Kostapanos, Michalis, Nodale, Marianna, Petchey, William, Sheeran, Thomas, Underwood, Jonathan, Jayne, David R, Nagra, Deepak, Bird, Georgina, Davies, Rhys John, Forde, Donall, Nye, Clemency, Balan, Andrea, Bird, Sam, Britten, Vianne, Broad, Lauren, Evans, Teriann, Frayling, Sharon, Gray, Laura, Haynes, Matthew, Oliver, Catherine, Rahilly, Karen, Williams, Gail, Ahmed, Tanwir, Bayliss, Carrie, Byrne, Natalie, Hernan-Sancho, Elena, Kasanicki, Mary, Stockley, Louise, Templin, Heike, Fisk, Marie, Goodman, James, Graggaber, Johann, Gray, Joanna, Gudu, Tania, Kulkarni, Spoorthy, Ni Lu, Ing, Masters, Peta, Mir, Fraz, Stober, Carmel, Abercrombie, Donna, Bermperi, Areti, Burns, Stella, Canna, Laura, Domingo, Jason, Hodges, Kathy, Jose, Sherly, Kourampa, Evgenia, Meadows, Anne, Mendoza, Vivien, Mushapaizdi, Thelma, Nacorda, Aileen, Pasquale, Ciro, Read, Debbie, Rowlands, Jane, Ruffulo, Valentina, Soave, Carlotta, Titti, Lissamma, Tordesillas, Hugo, Wright, Samantha, Scott, Kathryn, Sharma, Varun, Cathcart, Susanne, Rimmer, Dominic, Semple, Gary, Sheeran, Tom, Phiri, Laurence, Plumbe, Ann, Bhagat, Shweta, Moody, Anne Margaret, Kellett, Jo, Bukhari, Marwan, Burns, Karen, Crayton, Susanna, Fielding, Andra, Simpson, Kerry, Shah, Andrew, Thatcher, Hilary, Makkuni, Damodar, Harrison, Wendy, Jain, Thrusha, Patrick, Jean, Pratt, Arthur, Sheerin, Neil S, Kavanagh, David, Barr, Andrew, Baldwin, Kelly, Judd, Claire, McAlinden, Paul, McCormack, Louise, Stephenson, Elaine, Sharma, Sunil, Cross, Elizabeth L A, Bracewell, Kirsty, Musiol, Monika, Seal, Matthew, Cope, Andrew, Koduri, Gouri, Mercioniu, Mihaela, Kunhunny, Swapna, Pollard, Louise, Coakley, Gerald, Gupta, Sunil, Holloway, Amelia, Pilgrim, Samia, Treus, Estefania, Boehmer, Gabriele, Beranova, Eva, Ionita, Ana, Allen, Louise, Deery, Joanne, Hazelton, Tracy, Knight, Alicia, Price, Carly, Tilbey, Sorrell, Bradbury, Charlotte, Willis, Joanna, Drury, Kay, Putensen, Daniel, Schmidtmann, Anja, Dimitriadis, Georgios K, Gogoi, Sukanya, Vidler, Jennifer, Griffiths, Nicola, Rajasekaran, Arvind, Orme, Amy, Devenport, Debbie, Nisar, Muhammad, Ustianowski, Andrew, Lindergard, Gabriella, Uriel, Alison, Hey, Samuel, Lamb, Thomas, Bruce, Michelle, Flaherty, Jan, Fox, Claire, Parfrey, Helen, Dorey, Kane, and Petchey, William G

Published
2023
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5. Cardiovascular Outcomes in Acute Coronary Syndrome and Malnutrition: A Meta-Analysis of Nutritional Assessment Tools

Author

Lai, Angeline RX., Warrier, Manish, Ng, Ethel ZX., Lin, Chaoxing, Chin, Yip Han, Kong, Gwyneth, Anand, Vickram V., Lee, Ethan CZ., Lai, Haoxing, Ng, Hung Wei, Goh, Rachel SJ., Chong, Bryan, Muthiah, Mark D., Khoo, Chin Meng, Wang, Jiong-Wei, Tse, Gary, Loh, Poay Huan, Mehta, Anurag, Brown, Adrian, Dimitriadis, Georgios K., Chan, Mark Y., and Chew, Nicholas W.S.

Published
2023
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6. Socioeconomic deprivation and prognostic outcomes in acute coronary syndrome: A meta-analysis using multidimensional socioeconomic status indices

Author

Anand, Vickram Vijay, Zhe, Ethan Lee Cheng, Chin, Yip Han, Goh, Rachel Sze Jen, Lin, Chaoxing, Kueh, Martin Tze Wah, Chong, Bryan, Kong, Gwyneth, Tay, Phoebe Wen Lin, Dalakoti, Mayank, Muthiah, Mark, Dimitriadis, Georgios K., Wang, Jiong-Wei, Mehta, Anurag, Foo, Roger, Tse, Gary, Figtree, Gemma A., Loh, Poay Huan, Chan, Mark Y., Mamas, Mamas A., and Chew, Nicholas W.S.

Published
2023
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7. Barriers and Facilitators to Engagement With a Weight Management Intervention in Asian Patients With Overweight or Obesity: A Systematic Review

Author

Anand, Vickram Vijay, Zhe, Ethan Lee Cheng, Chin, Yip Han, Lim, Wen Hui, Goh, Rachel Sze Jen, Lin, Chaoxing, Ng, Cheng Han, Kong, Gwyneth, Tay, Phoebe Wen Lin, Devi, Kamala, Muthiah, Mark, Singh, Vijai, Chu, Dinh-Toi, Khoo, Chin Meng, Chan, Mark Y., Dimitriadis, Georgios K., Foo, Roger, and Chew, Nicholas W.S.

Published
2023
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8. The implications of defining obesity as a disease: a report from the Association for the Study of Obesity 2021 annual conference

Author

Luli, Migena, Yeo, Giles, Farrell, Emma, Ogden, Jane, Parretti, Helen, Frew, Emma, Bevan, Stephen, Brown, Adrian, Logue, Jennifer, Menon, Vinod, Isack, Nadya, Lean, Michael, McEwan, Chris, Gately, Paul, Williams, Simon, Astbury, Nerys, Bryant, Maria, Clare, Kenneth, Dimitriadis, Georgios K., Finlayson, Graham, Heslehurst, Nicola, Johnson, Brett, Le Brocq, Sarah, Roberts, Audrey, McGinley, Patrick, Mueller, Julia, O'Kane, Mary, Batterham, Rachel L., Roberts, Kath, and Miras, Alexander Dimitri

Published
2023
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9. The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019

Author

Chong, Bryan, Kong, Gwyneth, Shankar, Kannan, Chew, H.S. Jocelyn, Lin, Chaoxing, Goh, Rachel, Chin, Yip Han, Tan, Darren Jun Hao, Chan, Kai En, Lim, Wen Hui, Syn, Nicholas, Chan, Siew Pang, Wang, Jiong-Wei, Khoo, Chin Meng, Dimitriadis, Georgios K., Wijarnpreecha, Karn, Sanyal, Arun, Noureddin, Mazen, Siddiqui, Mohammad Shadab, Foo, Roger, Mehta, Anurag, Figtree, Gemma A., Hausenloy, Derek J., Chan, Mark Y., Ng, Cheng Han, Muthiah, Mark, Mamas, Mamas A., and Chew, Nicholas W.S.

Published
2023
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10. Trends and predictions of malnutrition and obesity in 204 countries and territories: an analysis of the Global Burden of Disease Study 2019

Author

Chong, Bryan, Jayabaskaran, Jayanth, Kong, Gwyneth, Chan, Yiong Huak, Chin, Yip Han, Goh, Rachel, Kannan, Shankar, Ng, Cheng Han, Loong, Shaun, Kueh, Martin Tze Wah, Lin, Chaoxing, Anand, Vickram Vijay, Lee, Ethan Cheng Zhe, Chew, H.S. Jocelyn, Tan, Darren Jun Hao, Chan, Kai En, Wang, Jiong-Wei, Muthiah, Mark, Dimitriadis, Georgios K., Hausenloy, Derek J., Mehta, Anurag J., Foo, Roger, Lip, Gregory, Chan, Mark Y., Mamas, Mamas A., le Roux, Carel W., and Chew, Nicholas W.S.

Published
2023
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11. Medication and supplement pharmacokinetic changes following bariatric surgery: A systematic review and meta‐analysis

Author

Lajeunesse‐Trempe, Fannie, primary, Okroj, Dominika, additional, Ostarijas, Eduard, additional, Ramalho, Alan, additional, Tremblay, Eve‐Julie, additional, Llewellyn, David, additional, Harlow, Chris, additional, Chandhyoke, Nikhil, additional, Chew, Nicholas W. S., additional, Vincent, Royce P., additional, Tchernof, Andre, additional, Piché, Marie‐Eve, additional, Poirier, Paul, additional, Biertho, Laurent, additional, Morin, Marie‐Philippe, additional, Copeland, Caroline S., additional, and Dimitriadis, Georgios K., additional

Published
2024
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12. Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis

Author

Chong, Bryan, Jayabaskaran, Jayanth, Ruban, Jitesh, Goh, Rachel, Chin, Yip Han, Kong, Gwyneth, Ng, Cheng Han, Lin, Chaoxing, Loong, Shaun, Muthiah, Mark D., Khoo, Chin Meng, Shariff, Ezman, Chan, Mark Y., Lajeunesse-Trempe, Fannie, Tchernof, Andre, Chevli, Parag, Mehta, Anurag, Mamas, Mamas A., Dimitriadis, Georgios K., and Chew, Nicholas W.S.

Published
2023
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14. Clinical utility of point‐of‐care glucose testing in the assessment of gestational diabetes: Prospective cohort study.

Author

Al‐Hasani, Wiaam, Ranasinghe, Ruvini, Rogers, Helen, Spanier, William, Spears, Katie, Gayle, Carol, Long, Lisa, Dimitriadis, Georgios K., Hunt, Katharine F., and Vincent, Royce P.

Subjects
GESTATIONAL diabetes, POINT-of-care testing, GLUCOSE tolerance tests, BLOOD sugar, LONGITUDINAL method
Abstract

Objective: To assess the clinical utility of point‐of‐care (POC) capillary blood glucose (CBG) testing in the assessment of gestational diabetes mellitus (GDM) during oral glucose tolerance test (OGTT). Design: Prospective cohort study. Setting: Antenatal clinics at King's College Hospital. Population: Women screened for GDM between March and June 2020. Methods: The CBG was measured using the POC StatStrip® test and the venous plasma glucose (VPG) was measured by Roche analyser (Cobas 8000 c702). GDM was diagnosed based on the 2015 National Institute for Health and Clinical Excellence (NICE) Clinical Guideline criteria. The two methods were compared statistically using Analyse‐It 5.40.2. Main outcome measures: Diagnostic sensitivity, specificity, positive and negative predictive values (PPV and NPV) for the POC StatStrip® test, compared with VPG measured by reference laboratory method. Results: A total of 230 women were included. The number and percentage of women with glucose concentrations above the GDM threshold using the POC StatStrip® test versus laboratory VPG measurement was 15 (6.5%) versus eight (3.4%) at fasting and 105 (45.6%) versus 72 (31.1%) at 2 h, respectively. The sensitivity and specificity values (and 95% CIs) for the POC StatStrip® test were 88% (52%–99%) and 97% (93%–98%) at fasting and 97% (91%–99%) and 79% (71%–84%) at 2 h, respectively. However, the specificity and the NPV for the POC StatStrip® test for concentrations of ≤5.0 mmol/L at fasting or <7.5 mmol/L at 2 h were 100%, and the sensitivity and the PPV for concentrations of >9.5 mmol/L at 2 h were 100%. Conclusions: In our cohort the POC measurement of CBG cannot entirely replace the laboratory method for the OGTT; however, it can be used to rule out/rule in GDM for glucose concentrations of ≤5.0 mmol/L at fasting or <7.5/>9.5 mmol/L at 2 h. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Mechanisms of action of duodenal mucosal resurfacing in insulin resistant women with polycystic ovary syndrome

Author

Kaur, Vasha, Dimitriadis, Georgios K., Pérez-Pevida, Belen, Bansi, Davinder Singh, Jayasena, Channa, Bate, Danielle, Houghton, Rhian, Fielding, Barbara A., Balfoussia, Danai, Webber, Lisa, Miao, Yun, Mears, Frederick, Jackson, Nicola, Coppin, Lucy, Perez, Jeremiah, Williams, Megan, Johnson, Brett, Umpleby, Anne Margot, Randeva, Harpal S., and Miras, Alexander Dimitri

Published
2021
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16. Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia

Author

Hazlehurst, Jonathan, primary, Khoo, Bernard, additional, Lobato, Carolina Brito, additional, Ilesanmi, Ibiyemi, additional, Abbott, Sally, additional, Chan, Tin, additional, Pillai, Sanesh, additional, Maslin, Kate, additional, Purkayastha, Sanjay, additional, McGowan, Barbara, additional, Andrews, Rob, additional, Nicholson, Eveleigh, additional, McCullough, Katherine, additional, Albon, Lorraine, additional, Batterham, Rachel, additional, Dimitriadis, Georgios K, additional, Forbes, Shareen, additional, Bewick, Gavin, additional, and Tan, Tricia M-M, additional

Published
2024
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17. Efficacy and safety of tirzepatide, GLP‐1 receptor agonists, and other weight loss drugs in overweight and obesity: a network meta‐analysis

Author

Pan, Xin‐Hui, primary, Tan, Bryan, additional, Chin, Yip Han, additional, Lee, Ethan Cheng Zhe, additional, Kong, Gwyneth, additional, Chong, Bryan, additional, Kueh, Martin, additional, Khoo, Chin Meng, additional, Mehta, Anurag, additional, Majety, Priyanka, additional, Grandhi, Gowtham R., additional, Dimitriadis, Georgios K., additional, Foo, Roger, additional, Chew, Nicholas W. S., additional, Le Roux, Carel W., additional, Mamas, Mamas A., additional, and Chan, Mark Y., additional

Published
2024
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20. Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia

Author

Hazlehurst, Jonathan, Khoo, Bernard, Lobato, Carolina Brito, Ilesanmi, Ibiyemi, Abbott, Sally, Chan, Tin, Pillai, Sanesh, Maslin, Kate, Purkayastha, Sanjay, McGowan, Barbara, Andrews, Rob, Nicholson, Eveleigh, McCullough, Katherine, Albon, Lorraine, Batterham, Rachel, Dimitriadis, Georgios K., Forbes, Shareen, Bewick, Gavin, Tan, Tricia M.M., Hazlehurst, Jonathan, Khoo, Bernard, Lobato, Carolina Brito, Ilesanmi, Ibiyemi, Abbott, Sally, Chan, Tin, Pillai, Sanesh, Maslin, Kate, Purkayastha, Sanjay, McGowan, Barbara, Andrews, Rob, Nicholson, Eveleigh, McCullough, Katherine, Albon, Lorraine, Batterham, Rachel, Dimitriadis, Georgios K., Forbes, Shareen, Bewick, Gavin, and Tan, Tricia M.M.

Abstract

Post-bariatric hypoglycaemia (PBH) is typically a post-prandial hypoglycaemia occurring about 2–4 h after eating in individuals who have undergone bariatric surgery. PBH develops relatively late after surgery and often after discharge from post-surgical follow-up by bariatric teams, leading to variability in diagnosis and management in non-specialist centres. Aim: The overall aim was to improve and standardise clinical practice in the diagnosis and management of PBH. The objectives were: (1) to undertake an up-to-date review of the current literature; (2) to formulate practical and evidence-based guidance regarding the diagnosis and treatment of PBH; (3) to recommend future avenues for research in this condition. Method: A scoping review was undertaken after an extensive literature search. A consensus on the guidance and confidence in the recommendations was reached by the steering group authors prior to review by key stakeholders. Outcome: We make pragmatic recommendations for the practical diagnosis and management of PBH, including criteria for diagnosis and recognition, as well as recommendations for research areas that should be explored. Plain English summary Post-bariatric hypoglycaemia (PBH) is a condition that commonly affects people who have undergone weight loss surgery. In this condition, people develop low blood sugar occurring about 2–4 h after meals, leading to debilitating symptoms such as hunger, sweating, anxiety, palpitations and even blackouts and fainting. PBH is becoming more common as weight loss surgery is being taken up by more people to help with their weight and to help with diabetes. The condition often develops after the patient has been discharged from follow-up after their surgery, which can lead to inconsistent diagnosis and treatment in non-specialist healthcare centres. The lack of clear information and evidence in the existing scientific literature further contributes to the variation in care. To address this problem, the Society

Published
2024

21. Impact of insulin sensitization on metabolic and fertility outcomes in women with polycystic ovary syndrome and overweight or obesity—A systematic review, meta‐analysis, and meta‐regression.

Author

Samarasinghe, Suhaniya N. S., Ostarijas, Eduard, Long, Matthew J., Erridge, Simon, Purkayastha, Sanjay, Dimitriadis, Georgios K., and Miras, Alexander D.

Subjects
POLYCYSTIC ovary syndrome, INSULIN, BODY mass index, BLOOD sugar, FERTILITY, THYROID cancer, MENSTRUATION disorders
Abstract

Summary: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive‐age women. This systematic review, meta‐analysis, and meta‐regression aims to compare the effect of insulin sensitizer pharmacotherapy on metabolic and reproductive outcomes in women with PCOS and overweight or obesity. We searched online databases MEDLINE via OVID, EMBASE, Clinicaltrials.gov, and EudraCT for trials published from inception to November 13, 2023. Inclusion criteria were double‐blind, randomized controlled trials in women diagnosed with PCOS, body mass index (BMI) ≥ 25 kg/m2, which reported metabolic or reproductive outcomes. The intervention was insulin sensitization pharmacotherapy versus placebo or other agents. The primary outcomes were changes from baseline BMI, fasting blood glucose, and menstrual frequency. Nineteen studies were included in this review. Metformin had the most significant effect on the fasting plasma glucose and body mass index. Insulin sensitizer pharmacotherapy significantly reduced fasting plasma glucose, body mass index, fasting serum insulin, HOMA‐IR, sex hormone binding globulin, and total testosterone, but the effect size was small. There was a lack of menstrual frequency and live birth data. The results indicate a role for insulin sensitizers in improving the metabolic and, to a lesser degree, reproductive profile in these women. Further research should examine insulin sensitizers' effects on objective measures of fecundity. [ABSTRACT FROM AUTHOR]

Published
2024
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22. The impact of mitotane therapy on serum-free proteins in patients with adrenocortical carcinoma

Author

Lech, Magdalena, primary, Ranasinghe, Ruvini, additional, Vincent, Royce P, additional, Taylor, David R, additional, Ghataore, Lea, additional, Luxton, James, additional, Lajeunesse-Trempe, Fannie, additional, Roser, Pia, additional, Drakou, Eftychia E, additional, Chuah, Ling Ling, additional, Grossman, Ashley B, additional, Aylwin, Simon J B, additional, and Dimitriadis, Georgios K, additional

Published
2024
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28. OR20-01 Machine Learning-based Steroid Metabolome Analysis In Women With Polycystic Ovary Syndrome Reveals Three Distinct Androgen Excess Subtypes With Different Metabolic Risk Profiles.

Author

Rocha, Thaís P, primary, Melson, Eka, additional, Veen, Roland J, additional, Abdi, Lida, additional, McDonnell, Tara, additional, Tandl, Veronika, additional, Hawley, James, additional, Wittemans, Laura, additional, Anthony, Amarah, additional, Gilligan, Lorna, additional, Shaheen, Fozia, additional, Kempegowda, Punith, additional, Gillett, Caroline D T, additional, Cussen, Leanne, additional, Missbrenner, Cornelia, additional, Lajeunesse-Trempe, Fannie, additional, Gleeson, Helena, additional, Rees, Aled, additional, Robinson, Lynne, additional, Jayasenna, Channa, additional, Randeva, Harpal S, additional, Randeva, Harpal Singh, additional, Dimitriadis, Georgios K, additional, Gomes, Larissa G, additional, Sitch, Alice, additional, Vradi, Eleni, additional, Taylor, Angela E, additional, O'Reilly, Michael W, additional, Obermayer-Pietsch, Barbara Maria, additional, Biehl, Michael, additional, and Arlt, Wiebke, additional

Published
2023
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29. S1669 Efficacy and Safety of Tirzepatide for the Management of Obesity in People With or Without Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials

Author

Ayyan, Muhammad, primary, Zahid, Afra, additional, Mustafa, Biah, additional, Naveed, Aiman, additional, Umer, Mohammad, additional, Shehryar, Muhammad, additional, Ehsan, Muhammad, additional, Miras, Alexander D., additional, Samarasinghe, Suhaniya N. S., additional, Athar, Farwa, additional, Cheema, Huzaifa Ahmad, additional, Nawaz, Ahmad, additional, Shahid, Abia, additional, Nabeel, Ambreen, additional, Lajeunesse-Trempe, Fannie, additional, Dimitriadis, Georgios K., additional, and Awan, Rehmat Ullah, additional

Published
2023
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30. Effectiveness of a Novel Artificial Intelligence-assisted Weight Loss App on Improving Eating Behaviors: A Mixed-method Evaluation

Author

Chew, Han Shi Jocelyn, primary, Chew, Nicholas WS, additional, Loong, Shaun Ser Ern, additional, Lim, Su Lin, additional, Tam, Wai San Wilson, additional, Chin, Yip Han, additional, Chao, Ariana M, additional, Dimitriadis, Georgios K, additional, Gao, Yujia, additional, So, Jimmy Bok Yan, additional, Shabbir, Asim, additional, and Ngiam, Kee Yuan, additional

Published
2023
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32. Mortality, Cardiovascular, and Medication Outcomes in Patients With Myocardial Infarction and Underweight in a Meta-Analysis of 6.3 Million Patients

Author

Lin, Chaoxing, primary, Loke, Wan Hsien, additional, Ng, Bing Han, additional, Chin, Yip Han, additional, Chong, Bryan, additional, Goh, Rachel Sze Jen, additional, Kong, Gwyneth, additional, Ong, Christen En Ya, additional, Chan, Kai En, additional, Fu, Clarissa, additional, Idnani, Tasha, additional, Muthiah, Mark D., additional, Khoo, Chin Meng, additional, Foo, Roger, additional, Loh, Poay Huan, additional, Chan, Mark Y., additional, Brown, Adrian, additional, Dimitriadis, Georgios K., additional, and Chew, Nicholas W.S., additional

Published
2023
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34. Machine learning-based steroid metabolome analysis reveals three distinct subtypes of polycystic ovary syndrome and implicates 11-oxygenated androgens as major drivers of metabolic risk

Author

Melson, Eka, primary, Rocha, Thais P., additional, Veen, Roland J., additional, Abdi, Lida, additional, Mcdonnell, Tara, additional, Tandl, Veronika, additional, Hawley, James M., additional, Wittemans, Laura B.L., additional, Anthony, Amarah V., additional, Gilligan, Lorna C., additional, Shaheen, Fozia, additional, Kempegowda, Punith, additional, Gillett, Caroline D.T, additional, Cussen, Leanne, additional, Missbrenner, Cornelia, additional, Lajeunesse-Trempe, Fannie, additional, Gleeson, Helena, additional, Aled, Rees D., additional, Robinson, Lynne, additional, Jayasena, Channa, additional, Randeva, Harpal S., additional, Dimitriadis, Georgios K., additional, Gomes, Larissa, additional, Sitch, Alice J., additional, Vradi, Eleni, additional, Taylor, Angela E., additional, O'Reilly, Michael W., additional, Obermayer-Pietsch, Barbara, additional, Biehl, Michael, additional, and Arlt, Wiebke, additional

Published
2023
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36. Higher Risk of Adverse Cardiovascular Outcomes in Females with Type 2 Diabetes Mellitus: An Umbrella Review of Systematic Reviews

Author

Yaow, Clyve Yu Leon, primary, Chong, Bryan, additional, Chin, Yip Han, additional, Kueh, Martin Tze Wah, additional, Ng, Cheng Han, additional, Chan, Kai En, additional, Tang, Ansel Shao Pin, additional, Chung, Charlotte, additional, Goh, Rachel, additional, Kong, Gwyneth, additional, Muthiah, Mark, additional, Sukmawati, Indah, additional, Lukito, Antonia Anna, additional, Chan, Mark Y, additional, Khoo, Chin Meng, additional, Mehta, Anurag, additional, Mamas, Mamas A, additional, Dimitriadis, Georgios K, additional, and Chew, Nicholas W S, additional

Published
2023
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37. Socio-Demographic, Behavioral and Psychological Factors Associated with High BMI among Adults in a Southeast Asian Multi-Ethnic Society: A Structural Equation Model

Author

Chew, Han Shi Jocelyn, primary, Loong, Shaun Seh Ern, additional, Lim, Su Lin, additional, Tam, Wai San Wilson, additional, Chew, Nicholas W. S., additional, Chin, Yip Han, additional, Chao, Ariana M., additional, Dimitriadis, Georgios K., additional, Gao, Yujia, additional, So, Bok Yan Jimmy, additional, and Shabbir, Asim, additional

Published
2023
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38. The global burden of metabolic disease: Data from 2000 to 2019

Author

Chew, Nicholas W.S., primary, Ng, Cheng Han, additional, Tan, Darren Jun Hao, additional, Kong, Gwyneth, additional, Lin, Chaoxing, additional, Chin, Yip Han, additional, Lim, Wen Hui, additional, Huang, Daniel Q., additional, Quek, Jingxuan, additional, Fu, Clarissa Elysia, additional, Xiao, Jieling, additional, Syn, Nicholas, additional, Foo, Roger, additional, Khoo, Chin Meng, additional, Wang, Jiong-Wei, additional, Dimitriadis, Georgios K., additional, Young, Dan Yock, additional, Siddiqui, Mohammad Shadab, additional, Lam, Carolyn S.P., additional, Wang, Yibin, additional, Figtree, Gemma A., additional, Chan, Mark Y., additional, Cummings, David E., additional, Noureddin, Mazen, additional, Wong, Vincent Wai-Sun, additional, Ma, Ronald Ching Wan, additional, Mantzoros, Christos S., additional, Sanyal, Arun, additional, and Muthiah, Mark Dhinesh, additional

Published
2023
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39. A two‐decade population‐based study on the effect of hypertension in the general population with obesity in the United States

Author

Kong, Gwyneth, primary, Chin, Yip H., additional, Lim, Jieyu, additional, Ng, Cheng H., additional, Kannan, Shankar, additional, Chong, Bryan, additional, Lin, Chaoxing, additional, Chan, Kai E., additional, Anand, Vickram V., additional, Lee, Ethan C. Z., additional, Loong, Shaun, additional, Wong, Zhen Y., additional, Khoo, Chin M., additional, Muthiah, Mark, additional, Foo, Roger, additional, Dimitriadis, Georgios K., additional, Figtree, Gemma A., additional, Wang, Yibin, additional, Chan, Mark, additional, and Chew, Nicholas W. S., additional

Published
2023
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40. The implications of defining obesity as a disease:a report from the Association for the Study of Obesity 2021 annual conference

Author

Luli, Migena, Yeo, Giles, Farrell, Emma, Ogden, Jane, Parretti, Helen, Frew, Emma, Bevan, Stephen, Brown, Adrian, Logue, Jennifer, Menon, Vinod, Isack, Nadya, Lean, Michael, McEwan, Chris, Gately, Paul, Williams, Simon, Astbury, Nerys, Bryant, Maria, Clare, Kenneth, Dimitriadis, Georgios K., Finlayson, Graham, Heslehurst, Nicola, Johnson, Brett, Le Brocq, Sarah, Roberts, Audrey, McGinley, Patrick, Mueller, Julia, O'Kane, Mary, Batterham, Rachel L., Miras, Alexander Dimitri, Luli, Migena, Yeo, Giles, Farrell, Emma, Ogden, Jane, Parretti, Helen, Frew, Emma, Bevan, Stephen, Brown, Adrian, Logue, Jennifer, Menon, Vinod, Isack, Nadya, Lean, Michael, McEwan, Chris, Gately, Paul, Williams, Simon, Astbury, Nerys, Bryant, Maria, Clare, Kenneth, Dimitriadis, Georgios K., Finlayson, Graham, Heslehurst, Nicola, Johnson, Brett, Le Brocq, Sarah, Roberts, Audrey, McGinley, Patrick, Mueller, Julia, O'Kane, Mary, Batterham, Rachel L., and Miras, Alexander Dimitri

Abstract

Unlike various countries and organisations, including the World Health Organisation and the European Parliament, the United Kingdom does not formally recognise obesity as a disease. This report presents the discussion on the potential impact of defining obesity as a disease on the patient, the healthcare system, the economy, and the wider society. A group of speakers from a wide range of disciplines came together to debate the topic bringing their knowledge and expertise from backgrounds in medicine, psychology, economics, and politics as well as the experience of people living with obesity. The aim of their debate was not to decide whether obesity should be classified as a disease but rather to explore what the implications of doing so would be, what the gaps in the available data are, as well as to provide up-to-date information on the topic from experts in the field. There were four topics where speakers presented their viewpoints, each one including a question-and-answer section for debate. The first one focused on the impact that the recognition of obesity could have on people living with obesity regarding the change in their behaviour, either positive and empowering or more stigmatising. During the second one, the impact of defining obesity as a disease on the National Health Service and the wider economy was discussed. The primary outcome was the need for more robust data as the one available does not represent the actual cost of obesity. The third topic was related to the policy implications regarding treatment provision, focusing on the public's power to influence policy. Finally, the last issue discussed, included the implications of public health actions, highlighting the importance of the government's actions and private stakeholders. The speakers agreed that no matter where they stand on this debate, the goal is common: to provide a healthcare system that supports and protects the patients, strategies that protect the economy and broader society, and po

Published
2023

42. Diagnosis and management of parathyroid carcinoma: a state of the art review

Author

Roser, Pia, primary, Leca, Bianca M, additional, Coelho, Claudia, additional, Schulte, Klaus-Martin, additional, Gilbert, Jackie, additional, Drakou, Eftychia E, additional, Kosmas, Christos, additional, Chuah, Ling Ling, additional, Wassati, Husam, additional, Miras, Alexander D., additional, Crane, James, additional, Aylwin, Simon J B, additional, Grossman, Ashley B., additional, and Dimitriadis, Georgios K., additional

Published
2023
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44. The efficacy of GLP‐1RAs for the management of postprandial hypoglycemia following bariatric surgery: a systematic review

Author

Llewellyn, David C., primary, Logan Ellis, Hugh, additional, Aylwin, Simon J. B., additional, Oštarijaš, Eduard, additional, Green, Shauna, additional, Sheridan, William, additional, Chew, Nicholas W. S., additional, le Roux, Carel W., additional, Miras, Alexander D., additional, Patel, Ameet G., additional, Vincent, Royce P., additional, and Dimitriadis, Georgios K., additional

Published
2022
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48. The incidence and clinical significance of metabolically active brown adipose tissue in patients with pheochromocytomas and paragangliomas: A retrospective cohort study, systematic review and meta-analysis

Author

Onyema, Michael, primary, Ostarijas, Eduard, additional, Minhas, Raisa, additional, Roy, Aparajita, additional, Kearney, Jessica, additional, Omran, Asma, additional, Zair, Zoulikha, additional, Reynolds, Saira, additional, Mulholland, Nicola, additional, Corcoran, Benjamin, additional, Halim, Mohammad, additional, Aylwin, Simon, additional, and Dimitriadis, Georgios K, additional

Published
2022
Full Text
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