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A total of 710 pigs (Line 400 × 200, DNA, Columbus, net energy (NE)) were used in two experiments (Exp. 1: initially, 6.3 ± 0.05 kg; Exp. 2: initially, 6.8 ± 0.05 kg) to evaluate the effects of two medium-chain fatty acid (MCFA) based products on nursery pig growth performance. Following their arrival at the nursery facility, pigs were randomized to pens (five pigs per pen) and allowed a 4-d acclimation period. Thereafter, pens of pigs were blocked by initial weight and randomized to dietary treatment. In Exp. 1, the dietary treatments were a dose titration of: 0%, 0.5%, 1.0%, or 2.0% MCFA-based additive, as well as a diet including 1.0% MCFA from a 1:1:1 blend of C6:0, C8:0, and C10:0. In Exp.2, dietary treatments consisted of a basal diet containing no MCFA (control), the control diet with a 1.0% inclusion of four different blends of MCFA, lactic acid, and monolaurin or a diet with 1.0% added MCFA (a 1:1:1 blend of C6:0, C8:0, and C10:0). The four blends consisted of 50% C6:0, 20% lactic acid, and increasing levels of monolaurin (0%, 10%, 20%, and 30%) at the expense of C12:0 (30%, 20%, 10%, and 0%). Treatment diets were formulated and manufactured in two dietary phases. Data were analyzed as a randomized complete block design with pen as the experimental unit. In Exp. 1, overall (days 0–34), increasing CaptiSURE increased (linear, P ≤ 0.014) average daily gain (ADG) and average daily feed intake (ADFI). Feed efficiency improved (quadratic, P = 0.002) with increasing CaptiSURE up to 1.0% of the diet with no benefit thereafter. There was no evidence for differences between pigs fed 1.0% CaptiSURE and pigs fed the 1.0% MCFA blend of C6:0, C8:0, and C10:0. In Exp. 2, overall (days 0–35), pigs fed the 1.0% 1:1:1 MCFA blend had increased (P < 0.034) ADFI and ADG resulting in 0.9 kg greater final weight (P = 0.014) compared with the control group. There was no evidence that the mean performance of pigs fed the four blends of MCFA, lactic acid, and monolaurin were different from the pigs fed the control diet. In summary, the addition of a 1.0% 1:1:1 blend of C6:0, C8:0, and C10:0 in nursery pig diets improved ADG, ADFI, and gain to feed ratio (G:F) compared with pigs fed the control diet. In addition, providing nursery pigs with the MCFA product CaptiSURE, up to 2% of the diet, resulted in linear improvements in ADG and ADFI. Altering the C12:0 to monolaurin ratio and adding lactic acid did not improve growth performance compared with pigs fed the control diet.

A total of 350 pigs (DNA 400×200, initial BW=6.3 kg) were used in a 34-d growth trial to evaluate the effects of a medium chain fatty acid (MCFA)-based feed additive in nursery pig diets. Following arrival to the nursery facility, pigs were randomized to pens (5 pigs per pen) and allowed a 4-d acclimation period. Thereafter, pens of pigs were blocked by BW and randomized to 1 of 5 dietary treatments (14 pens per treatment). Treatments were a dose response of 0, 0.5, 1.0, or 2.0% MCFA-based additive (CaptiSURE, Kemin Industries, Inc.; Des Moines, IA) as well as a treatment including 1.0% MCFA from a 1:1:1 blend of C6, C8, and C10 (Sigma Aldrich, St. Louis, MO). Treatment diets were formulated and manufactured in two dietary phases (d 0 to 13 and 13 to 34). Data were analyzed as a randomized complete block design with pen serving as the experimental unit. Overall (d 0 to 34), increasing CaptiSURE increased (linear, P ≤ 0.014) ADG and ADFI. Feed efficiency improved (quadratic, P = 0.002) with increasing CaptiSURE up to 1% of the diet with no benefit thereafter. As a result of the linear improvement in ADG, pigs fed 2.0% CaptiSURE were 1.8 kg heavier (P = 0.05) than pigs fed diets without MCFA at d 34. There was no evidence for differences between pigs fed 1.0% CaptiSURE and pigs fed the 1.0% MCFA blend of C6, C8, and C10 in phase 1, phase 2 or in overall performance. In summary, the addition of up to 2% of this MCFA-based additive in nursery pig diets resulted in linear improvements in ADG and ADFI. The MCFA-based feed additive also resulted in a similar improvement in growth performance as the C6, C8, and C10 MCFA blend when both were added at 1% of the diet.

Experimental objectives of this study were to determine effects of formaldehyde treatment on the chemical composition of spray-dried plasma (SDP) and to test the hypothesis that growth performance of pigs fed formaldehyde-treated diets containing SDP or diets containing formaldehyde-treated SDP is not reduced compared with pigs fed untreated control diets. Sal CURB ASF liquid antimicrobial and CURB RM Extra liquid mold inhibitor (Kemin Industries, Des Moines, IA) were applied on SDP at 0.1% or 0.3% to determine effects of the products on chemical and functional properties of SDP. Regardless of product, there were no changes in SDP for analyzed protein, ash, pH, or moisture concentration, but IgG concentration in SDP was decreased 8% and 24%, respectively, for 0.1% and 0.3% inclusion of Sal CURB or CURB RM. Two feeding studies using weaned pigs were conducted to determine effects of formaldehyde applied at 0.3% to SDP (experiment 1) or 0.3% to a complete diet containing 5% SDP (experiment 2). Experiment 1 pigs (n = 265) were weaned at 20 ± 2 d of age and allotted to five treatment groups. Experiment 2 pigs (n = 135) were weaned in two groups at 20 ± 2 d of age and allotted to three treatments groups. In experiment 1, the untreated control diet contained soy protein concentrate (SPC) and test diets contained 2.5% or 5.0% SDP without or with formaldehyde treatment. In experiment 2, formaldehyde was applied to a diet containing 5% SDP and an untreated SPC control diet and an untreated diet containing 5% SDP were also included in the experiment. In experiment 1, linear increases (P < 0.05) in average daily gain (ADG), average daily feed intake (ADFI), and gain-to-feed ratio (G:F) were observed as SDP was included in the diets and the relative bioavailability of formaldehyde-treated SDP was 62% (P = 0.018) if calculations were based on ADG and 15% (P = 0.031) if calculations were based on ADFI. In experiment 2, pigs fed the SDP diet untreated or treated with formaldehyde had increased (P < 0.05) final body weight, ADG, ADFI, and G:F compared with pigs fed the control diet. However, formaldehyde treatment of the plasma-containing diet did not affect pig growth performance compared with pigs fed the untreated SDP diet. In conclusion, formaldehyde treatment applied directly on SDP affects analyzed concentrations of IgG and reduces growth rate of pigs. Treating a complete diet containing 5% SDP with formaldehyde did not affect pig growth performance, and pigs fed diets containing SDP had improved growth performance than those fed the control diet without SDP.

Previous studies have shown that the inclusion of medium chain fatty acids (MCFA) results in an improvement in nursery pig performance. Therefore, the objective of this study was to evaluate a proprietary C8:C10 MCFA blend (CaptiSURE, Kemin Industries, Inc., Des Moines, IA) on nursery pig performance. A total of 360 weaned piglets (initial BW = 6.1 kg) were randomly assigned to a control (no MCFA blend) or 10 kg/t MCFA blend (10 pigs/pen, 18 replicate pens/treatment), in which MCFA blend was substituted at the expense of tallow at a 1:1 rate. Diets were manufactured in 3 dietary phases (d 0–7, 7–21, and 21–42) in pelleted form. Due to an unintended bacterial challenge at the sow farm, pigs were treated with amoxicillin using a pulse protocol (48 hrs on / 48 hrs off) from placement to d 21. Data were analyzed using the students T-test procedure, and pen served as the experimental unit. Within dietary phase 2 (d 7–21), the inclusion of MCFA blend improved ADG (264g vs 326g, P = 0.017) and G:F (0.79 vs 0.89, P = 0.005), while exhibiting a trend to improve ADFI (330g vs 364g, P = 0.080). Within dietary phase 3 (d 21–42), the inclusion of MCFA blend improved ADG (518g vs 581g, P = 0.024) and ADFI (719g vs 799g, P = 0.006). Overall (d 0–42), the inclusion of MCFA blend improved ADG (379g vs 438g, P = 0.007), ADFI (503g vs 0.562g, P = 0.009), and G:F (0.75 vs 0.78, P = 0.042), resulting in a 2 kg heavier pig (P = 0.043). In summary, the inclusion of a proprietary C8:C10 MCFA blend at 1.0% in nursery pig diets improved growth performance.