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1. Defining the variant-phenotype correlation in patients affected by Noonan syndrome with the RAF1:c.770C>T p.(Ser257Leu) variant

2. Loss-of-function variants in ERF are associated with a Noonan syndrome-like phenotype with or without craniosynostosis

3. DNA methylation profiling in Kabuki syndrome: reclassification of germline KMT2D VUS and sensitivity in validating postzygotic mosaicism

6. Heterozygosity for loss-of-function variants in LZTR1 is associated with isolated multiple café-au-lait macules

7. Neurological and psychiatric phenotype of a multicenter cohort of patients with SETD5-related neurodevelopmental disorder

8. Williams–Beuren syndrome shapes the gut microbiota metaproteome

9. FOXI3 pathogenic variants cause one form of craniofacial microsomia

10. Clinical variability in DYNC2H1-related skeletal ciliopathies includes Ellis-van Creveld syndrome

14. Cardiac function in adolescents and young adults with 22q11.2 deletion syndrome without congenital heart disease

16. Prenatal vs postnatal diagnosis of 22q11.2 deletion syndrome: cardiac and noncardiac outcomes through 1 year of age

17. Unique Features of Cardiovascular Involvement and Progression in Children with Marfan Syndrome Justify Dedicated Multidisciplinary Care

20. Contributors

22. Clinical delineation, sex differences, and genotype–phenotype correlation in pathogenic KDM6A variants causing X-linked Kabuki syndrome type 2

23. Clinical and molecular cytogenetic studies of five new patients with 20q11q12 deletion and review of the literature: Proposition of two critical regions.

26. Case report: A new de novo 6q21q22.1 interstitial deletion case in a girl with cerebellar vermis hypoplasia and developmental delay and literature review

27. Matrisome and Immune Pathways Contribute to Extreme Vascular Outcomes in Williams–Beuren Syndrome

28. Variants of SOS2 are a rare cause of Noonan syndrome with particular predisposition for lymphatic complications

29. Rare copy number variants and congenital heart defects in the 22q11.2 deletion syndrome.

30. Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome

31. Movement disorder phenotype in CTNNB1-syndrome: A complex but recognizable phenomenology

35. Congenital Heart Defects in Patients with Molecularly Confirmed Sotos Syndrome.

37. Prenatal versus Postnatal Diagnosis of 22q11.2 Deletion Syndrome: Cardiac and Non-Cardiac Outcomes through 1 Year of Age

41. Partial atrioventricular canal defect and aortic coarctation associated with variants in GDF1 and NOTCH1 genes: A case report.

42. Deep phenotyping of the neuroimaging and skeletal features in KBG syndrome: a study of 53 patients and review of the literature

45. Matrisome and Immune Pathways Contribute to Extreme Vascular Outcomes in Williams-Beuren Syndrome.

46. Gain-of-function SOS1 mutations cause a distinctive form of noonan syndrome

48. Deep Intronic LINE-1 Insertions in NF1: Expanding the Spectrum of Neurofibromatosis Type 1-Associated Rearrangements

49. Bi-allelic SNAPC4 variants dysregulate global alternative splicing and lead to neuroregression and progressive spastic paraparesis

50. Neurodevelopmental and genetic findings in neonates with intracranial arteriovenous shunts: A case series

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