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2. SNAP Satellite Focal Plane Development

Author

Bebek, C., Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Baltay, C., Barrelet, E., Basa, S., Bercovitz, J., Bergstrom, L., Berstein, G.P., Bester, M., Bohlin, R., Bonissent, A., Bower, C., Campbell, M., Carithers, W., Commins, E., Day, C., Deustua, S., DiGennaro, R., Ealet, A., Ellis, R., Emmett, W., Eriksson, M., Fouchez, D., Fruchter, A., Genat, J-F., Goldhaber, G., Goobar, A., Groom, D., Heetderks, H., Holland, S., Huterer, D., Johnson, W., Kadel, R., Karcher, A., Kim, A., Kolbe, W., Lafever, R., Lamoureaux, J., Lampton, M., Lefevre, O., Levi, M., Levin, D., Linder, E., Loken, S., Malina, R., Mazure, A., McKay, T., McKee, S., Miquel, R., Morgan, N., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Roe, N., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Prieto, E., Rabinowitz, D., Refregier, A., Rhodes, J., Schubnell, M., Sholl, M., Smadja, G., Smith, R., Smoot, G., Snyder, J., Spadafora, A., Szymkowiak, A., Tarle, G., Taylor, K., Tilquin, A., Tomasch, A., Vincent, D., von der Lippe, H., Walder, J-P., and Wang, G.

Subjects
Physics of elementary particles and fields, ASIC CCD optical filters focal plane detectors HgCdTe InGaAs spectrograph
Abstract

The proposed SuperNova/Acceleration Probe (SNAP) mission will have a two-meter class telescope delivering diffraction-limited images to an instrumented 0.7 square degree field in the visible and near-infrared wavelength regime. The requirements for the instrument suite and the present configuration of the focal plane concept are presented. A two year R&D phase, largely supported by the Department of Energy, is just beginning. We describe the development activities that are taking place to advance our preparedness for mission proposal in the areas of detectors and electronics.

Published
2003

3. Weak Lensing from Space I: Instrumentation and Survey Strategy

Author

Rhodes, Jason, Refregier, Alexandre, Massey, Richard, Albert, Justin, Bacon, David, Bernstein, Gary, Ellis, Richard, Jain, Bhuvnesh, Kim, Alex, Lampton, Mike, McKay, Tim, Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bester, M., Bonissent, A., Bower, C., Carithers, W., Commins, E., Day, C., Deustua, S., DiGennaro, R., Ealet, A., Eriksson, M., Fruchter, A., Genat, J.-F., Goldhaber, G., Goobar, A., Groom, D., Harris, S., Harvey, P., Heetderks, H., Holland, S., Huterer, D., Karcher, A., Kolbe, W., Kreiger, B., Lafever, R., Lamoureux, J., Levi, M., Devin, D., Linder, E., Loken, S., Malina, R., McKee, S., Miquel, R., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Tarle, G., Tomasch, A., Lippe, H. von der, Vincent, D., Walder, J.-P., and Wang, G.

Subjects
gravitational lensing SNAP
Abstract

A wide field space-based imaging telescope is necessary to fully exploit the technique of observing dark matter via weak gravitational lensing. This first paper in a three part series outlines the survey strategies and relevant instrumental parameters for such a mission. As a concrete example of hardware design, we consider the proposed Supernova/Acceleration Probe (SNAP). Using SNAP engineering models, we quantify the major contributions to this telescope's Point Spread Function (PSF). These PSF contributions are relevant to any similar wide field space telescope. We further show that the PSF of SNAP or a similar telescope will be smaller than current ground-based PSFs, and more isotropic and stable over time than the PSF of the Hubble Space Telescope. We outline survey strategies for two different regimes - a "wide" 300 square degree survey and a "deep" 15 square degree survey that will accomplish various weak lensing goals including statistical studies and dark matter mapping.

Published
2003

5. The SNS RFQ Commissioning

Author

Ratti, A., Ayers, J., Doolittle, L., DiGennaro, R., Gough, R.A., Hoff, M., Keller, R., MacGill, J., Staples, J., Thomae, R., Virostek, S., Yourd, R., and Aleksandrov, A.

Subjects
Particle accelerators, SNS Front End RFQ Commissioning
Published
2002

6. SNAP telescope

Author

Lampton, Michael L., Akerlof, C.W., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bernstein, G., Bester, M., Bonissent, A., Bower, C., Carithers Jr., W.C., Commins, E.D., Day, C., Deustua, S.E., DiGennaro, R., Ealet, A., Ellis, R.S., Eriksson, M., Fruchter, A., Genat, J.-F., Goldhaber, G., Goobar, A., Groom, D., Harris, S.E., Harvey, P.R., Heetderks, H.D., Holland, S.E., Huterer, D., Karcher, A., Kim, A.G., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Levi, M.E., Levin, D.S., Linder, E.V., Loken, S.C., Malina, R., Massey, R., McKay, T., McKee, S.P., Miquel, R., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Refregier, A., Rhodes, J., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Tarle, G., Tomasch, A., von der Lippe, H., Vincent, R., Walder, J.-P., and Wang, G.

Subjects
Classical and quantum mechanics, general physics
Published
2002

7. The SNAP near infrared detectors

Author

Tarle, G., Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bernstein, G., Bester, M., Bonissent, A., Bower, C., Carithers, W., Commins, E.D., Day, C., Deustua, S., DiGennaro, R., Ealet, Anne, Ellis, R.S., Eriksson, M., Fruchter, A., Genat, J.-F., Goldhaber, G., Goobar, A., Groom, D., Harris, S., Harvey, P., Heetderks, H., Holland, S., Huterer, D., Karcher, A., Kim, A., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Lampton, M., Levi, M.E., Levin, D., Linder, E., Loken, S., Malina, R., Massey, R., Miguel, R., McKay, T., McKee, S., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Refregier, A., Rhodes, J., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Tomasch, A., von der Lippe, H., Vincent, R., Walder, J., and Wang, G.

Subjects
Classical and quantum mechanics, general physics
Published
2002

8. Overview of the SuperNova/Acceleration probe (SNAP)

Author

Aldering, Gregory L., Akerlof, C.W., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bernstein, G.M., Bester, M., Bonissent, A., Bower, C.R., Carithers Jr., W.C., Commins, E.D., Day, C., Deustua, S.E., DiGennaro, R., Ealet, A., Ellis, R.S., Eriksson, M., Fruchter, A., Genat, J-F., Goldhaber, G., Goobar, A., Groom, D., Harris, S.E., Harvey, P.R.D, Heetderks, H.D., Holland, S.E., Huterer, D., Karcher, A., Kim, A.G., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Lampton, M.L., Levi, M.E., Levin, D.S., Linder, E.V., Loken, S.C., Malina, R., Massey, R., McKay, T., McKee, S.P., Miquel, R., Mortsell, E., Mostek, N., Mufson, S., Musser, J.A., Nugent, P.E., Oluseyi, H., Pain, R., Palaio, N., Pankow, D.H., Perlmutter, S., Pratt, R., Prieto, E., Refregier, A., Rhodes, J., Robinson, K.E., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Tarle, G., Tomasch, A., von der Lippe, H., Vincent, D., Walder, J., and Wang, G.

Subjects
Classical and quantum mechanics, general physics
Published
2002

9. SNAP focal plane

Author

Lampton, Michael L., Kim, A., Akerlof, C.W., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Berkovitz, J., Bernstein, G., Bester, M., Bonissent, A., Bower, C., Carithers Jr., W.C., Commins, E.D., Day, C., Deustua, S.E., DiGennaro, R., Ealet, A., Ellis, R.S., Eriksson, M., Fruchter, A., Genat, J.-F., Goldhaber, G., Goobar, A., Groom, D., Harris, S.E., Harvey, P.R., Heetderks, H.D., Holland, S.E., Huterer, D., Karcher, A., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Levi, M.E., Levin, D.S., Linder, E.V., Loken, S.C., Malina, R., Massey, R., McKay, T., McKee, S.P., Miquel, R., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Refregier, A., Rhodes, J., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Tarle, G., Tomasch, A., von der Lippe, H., Vincent, R., Walder, J.-P., and Wang, G.

Subjects
Classical and quantum mechanics, general physics
Published
2002

10. Wide-field surveys from the SNAP mission

Author

Kim, Alex G., Akerlof, C.W., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bernstein, G., Bester, M., Bonissent, A., Bower, C., Carithers Jr., W.C., Commins, E.D., Day, C., Deustua, S.E., DiGennaro, R., Ealet, A., Ellis, R.S., Eriksson, M., Fruchter, A., Genat, J.-F., Goldhaber, G., Goobar, A., Groom, D., Harris, S.E., Harvey, P.R., Heetderks, H.D., Holland, S.E., Huterer, D., Karcher, A., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Levi, M.E., Levin, D.S., Linder, E.V., Loken, S.C., Malina, R., Massey, R., McKay, T., McKee, S.P., Miquel, R., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Refregier, A., Rhodes, J., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Tarle, G., Tomasch, A., von der Lippe, H., Vincent, R., Walder, J.-P., and Wang, G.

Subjects
Physics of elementary particles and fields
Published
2002

13. Progress with the SNS front-end systems

Author

Keller, R., Abraham, W., Ayers, J.J., Cheng, D.W., Cull, P., DiGennaro, R., Doolittle, L., Gough, R.A., Greer, J.B., Hoff, M.D., Leung, K.N., Lewis, S., Lionberger, C., MacGill, R., Minamihara, Y., Monroy, M., Oshatz, D., Pruyn, J., Ratti, A., Reijonen, J., Schenkel, T., Staples, J.W., Syversrud, D., Thomae, R., Virostek, S., and Yourd, R.

Subjects
Particle accelerators, SNS Spallation Neutron Source Front End Systems
Published
2001

14. The Spallation Neutron Source accelerator system design

Author

Henderson, S., Abraham, W., Aleksandrov, A., Allen, C., Alonso, J., Anderson, D., Arenius, D., Arthur, T., Assadi, S., Ayers, J., Bach, P., Badea, V., Battle, R., Beebe-Wang, J., Bergmann, B., Bernardin, J., Bhatia, T., Billen, J., Birke, T., Bjorklund, E., Blaskiewicz, M., Blind, B., Blokland, W., Bookwalter, V., Borovina, D., Bowling, S., Bradley, J., Brantley, C., Brennan, J., Brodowski, J., Brown, S., Brown, R., Bruce, D., Bultman, N., Cameron, P., Campisi, I., Casagrande, F., Catalan-Lasheras, N., Champion, M., Chen, Z., Cheng, D., Cho, Y., Christensen, K., Chu, C., Cleaves, J., Connolly, R., Cote, T., Cousineau, S., Crandall, K., Creel, J., Crofford, M., Cull, P., Cutler, R., Dabney, R., Dalesio, L., Daly, E., Damm, R., Danilov, V., Davino, D., Davis, K., Dawson, C., Day, L., Deibele, C., Delayen, J., DeLong, J., Demello, A., DeVan, W., Digennaro, R., Dixon, K., Dodson, G., Doleans, M., Doolittle, L., Doss, J., Drury, M., Elliot, T., Ellis, S., Error, J., Fazekas, J., Fedotov, A., Feng, P., Fischer, J., Fox, W., Fuja, R., Funk, W., Galambos, J., Ganni, V., Garnett, R., Geng, X., Gentzlinger, R., Giannella, M., Gibson, P., Gillis, R., Gioia, J., Gordon, J., Gough, R., Greer, J., Gregory, W., Gribble, R., Grice, W., Gurd, D., Gurd, P., Guthrie, A., Hahn, H., Hardek, T., Hardekopf, R., Harrison, J., Hatfield, D., He, P., Hechler, M., Heistermann, F., Helus, S., Hiatt, T., Hicks, S., Hill, J., Hoff, L., Hoff, M., Hogan, J., Holding, M., Holik, P., Holmes, J., Holtkamp, N., Hovater, C., Howell, M., Hseuh, H., Huhn, A., Hunter, T., Ilg, T., Jackson, J., Jain, A., Jason, A., Jeon, D., Johnson, G., Jones, A., Joseph, S., Justice, A., Kang, Y., Kasemir, K., Keller, R., Kersevan, R., Kerstiens, D., Kesselman, M., Kim, S., Kneisel, P., Kravchuk, L., Kuneli, T., Kurennoy, S., Kustom, R., Kwon, S., Ladd, P., Lambiase, R., Lee, Y.Y., Leitner, M., Leung, K.-N., Lewis, S., Liaw, C., Lionberger, C., Lo, C.C., Long, C., Ludewig, H., Ludvig, J., Luft, P., Lynch, M., Ma, H., MacGill, R., Macha, K., Madre, B., Mahler, G., Mahoney, K., Maines, J., Mammosser, J., Mann, T., Marneris, I., Marroquin, P., Martineau, R., Matsumoto, K., McCarthy, M., McChesney, C., McGahern, W., McGehee, P., Meng, W., Merz, B., Meyer, R., Jr., Meyer, R., Sr., Miller, B., Mitchell, R., Mize, J., Monroy, M., Munro, J., Murdoch, G., Musson, J., Nath, S., Nelson, R., O׳Hara, J., Olsen, D., Oren, W., Oshatz, D., Owens, T., Pai, C., Papaphilippou, I., Patterson, N., Patterson, J., Pearson, C., Pelaia, T., Pieck, M., Piller, C., Plawski, T., Plum, M., Pogge, J., Power, J., Powers, T., Preble, J., Prokop, M., Pruyn, J., Purcell, D., Rank, J., Raparia, D., Ratti, A., Reass, W., Reece, K., Rees, D., Regan, A., Regis, M., Reijonen, J., Rej, D., Richards, D., Richied, D., Rode, C., Rodriguez, W., Rodriguez, M., Rohlev, A., Rose, C., Roseberry, T., Jr., Rowton, L., Roybal, W., Rust, K., Salazer, G., Sandberg, J., Saunders, J., Schenkel, T., Schneider, W., Schrage, D., Schubert, J., Severino, F., Shafer, R., Shea, T., Shishlo, A., Shoaee, H., Sibley, C., Sims, J., Smee, S., Smith, J., Smith, K., Spitz, R., Staples, J., Stein, P., Stettler, M., Stirbet, M., Stockli, M., Stone, W., Stout, D., Stovall, J., Strelo, W., Strong, H., Sundelin, R., Syversrud, D., Szajbler, M., Takeda, H., Tallerico, P., Tang, J., Tanke, E., Tepikian, S., Thomae, R., Thompson, D., Thomson, D., Thuot, M., Treml, C., Tsoupas, N., Tuozzolo, J., Tuzel, W., Vassioutchenko, A., Virostek, S., Wallig, J., Wanderer, P., Wang, Y., Wang, J.G., Wangler, T., Warren, D., Wei, J., Weiss, D., Welton, R., Weng, J., Weng, W-T., Wezensky, M., White, M., Whitlatch, T., Williams, D., Williams, E., Wilson, K., Wiseman, M., Wood, R., Wright, P., Wu, A., Ybarrolaza, N., Young, K., Young, L., Yourd, R., Zachoszcz, A., Zaltsman, A., Zhang, S., Zhang, W., Zhang, Y., and Zhukov, A.

Published
2014
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17. Deep Underground Science and Engineering Laboratory - Preliminary Design Report

Author

Lesko, K. T., primary, Acheson, S., additional, Alonso, J., additional, Bauer, P, additional, Chan, Y. -D, additional, Chinowsky, W., additional, Dangermond, S., additional, Detwiler, J. A., additional, Vries, S. D., additional, DiGennaro, R., additional, Exter, E., additional, Fernandez, F. B., additional, Freer, E. L., additional, Gilchriese, M. G.D., additional, Goldschmidt, A., additional, Grammann, B., additional, Griffing, W., additional, Harlan, B., additional, Haxton, W. C., additional, Headley, M., additional, Heise, J., additional, Hladysz, Z., additional, Jacobs, D., additional, Johnson, M., additional, Kadel, R., additional, Kaufman, R., additional, King, G., additional, Lanou, R., additional, Lemut, A., additional, Ligeti, Z, additional, Marks, S., additional, Martin, R. D., additional, Matthesen, J., additional, Matthew, B., additional, Matthews, W., additional, McConnell, R., additional, McElroy, W., additional, Meyer, D., additional, Norris, M., additional, Plate, D., additional, Robinson, K. E., additional, Roggenthen, W., additional, Salve, R., additional, Sayler, B., additional, Scheetz, J., additional, Tarpinian, J., additional, Taylor, D., additional, Vardiman, D., additional, Wheeler, R., additional, Willhite, J., additional, and Yeck, J., additional

Published
2017
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24. The LBL 55-Meter Spherical Grating Monochromator at SSRL

Author

McKinney, W.R., Howells, M.R., Lauritzen, T., Chin, J., DiGennaro, R., Fong, E., Gath, W., Guigli, J., Hogrefe, H., Meneghetti, J., Plate, D., Heimann, P.A., Terminello, Louis J., Ji, Z., Shirley, D.A., and Senf, S.

Published
1989

25. Weak lensing from space I: instrumentation and survey strategy

Author

Rhodes, Jason, Refregier, Alexandre, Massey, Richard, Albert, Justin, Bacon, David, Bernstein, Gary, Ellis, Richard, Jain, Bhuvnesh, Kim, Alex, Lampton, Mike, McKay, Tim, Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Baltay, C., Barrelet, E., Bebek, C., Bergström, L., Bercovitz, J., Bester, M., Bigelow, B., Bohlin, R., Bonissent, A., Bower, C., Brown, M., Campbell, M., Carithers, W., Commins, E., Day, C., Deustua, S., DiGennaro, R., Ealet, A., Emmet, W., Eriksson, M., Fouchez, D., Fruchter, A., Genat, J-F., Gerdes, D., Gladney, L., Goldhaber, G., Goobar, A., Groom, D., Harris, S., Harvey, P., Heetderks, H., Holland, S., Huterer, D., Johnston, W., Karcher, A., Kolbe, W., Krieger, B., Kushner, G., Kuznetsova, N., Lafever, R., Lamoureux, J., Levi, M., Linder, E., Loken, S., Lorenzon, W., Malina, R., Mazure, A., McKee, S., Miquel, R., Morgan, N., Mörtsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Rabinowitz, D., Robinson, K., Roe, N., Rusin, D., Schubnell, M., Sholl, M., Smadja, G., Smith, R., Smoot, G., Snyder, J., Spadafora, A., Szymkowiak, A., Tarlé, G., Taylor, K., Tilquin, A., Tomasch, A., von der Lippe, H., Vincent, D., Walder, J.-P., and Wang, G.

Published
2004
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26. Deep Underground Science and Engineering Laboratory - Preliminary Design Report

Author

Lesko, KT, Acheson, S, Alonso, J, Bauer, P, Chan, Y-D, Chinowsky, W, Dangermond, S, Detwiler, JA, Vries, SD, DiGennaro, R, Exter, E, Fernandez, FB, Freer, EL, Gilchriese, MGD, Goldschmidt, A, Grammann, B, Griffing, W, Harlan, B, Haxton, WC, Headley, M, Heise, J, Hladysz, Z, Jacobs, D, Johnson, M, Kadel, R, Kaufman, R, King, G, Lanou, R, Lemut, A, Ligeti, Z, Marks, S, Martin, RD, Matthesen, J, Matthew, B, Matthews, W, McConnell, R, McElroy, W, Meyer, D, Norris, M, Plate, D, Robinson, KE, Roggenthen, W, Salve, R, Sayler, B, Scheetz, J, Tarpinian, J, Taylor, D, Vardiman, D, Wheeler, R, Willhite, J, Yeck, J, Lesko, KT, Acheson, S, Alonso, J, Bauer, P, Chan, Y-D, Chinowsky, W, Dangermond, S, Detwiler, JA, Vries, SD, DiGennaro, R, Exter, E, Fernandez, FB, Freer, EL, Gilchriese, MGD, Goldschmidt, A, Grammann, B, Griffing, W, Harlan, B, Haxton, WC, Headley, M, Heise, J, Hladysz, Z, Jacobs, D, Johnson, M, Kadel, R, Kaufman, R, King, G, Lanou, R, Lemut, A, Ligeti, Z, Marks, S, Martin, RD, Matthesen, J, Matthew, B, Matthews, W, McConnell, R, McElroy, W, Meyer, D, Norris, M, Plate, D, Robinson, KE, Roggenthen, W, Salve, R, Sayler, B, Scheetz, J, Tarpinian, J, Taylor, D, Vardiman, D, Wheeler, R, Willhite, J, and Yeck, J

Abstract

The DUSEL Project has produced the Preliminary Design of the Deep Underground Science and Engineering Laboratory (DUSEL) at the rehabilitated former Homestake mine in South Dakota. The Facility design calls for, on the surface, two new buildings - one a visitor and education center, the other an experiment assembly hall - and multiple repurposed existing buildings. To support underground research activities, the design includes two laboratory modules and additional spaces at a level 4,850 feet underground for physics, biology, engineering, and Earth science experiments. On the same level, the design includes a Department of Energy-shepherded Large Cavity supporting the Long Baseline Neutrino Experiment. At the 7,400-feet level, the design incorporates one laboratory module and additional spaces for physics and Earth science efforts. With input from some 25 science and engineering collaborations, the Project has designed critical experimental space and infrastructure needs, including space for a suite of multidisciplinary experiments in a laboratory whose projected life span is at least 30 years. From these experiments, a critical suite of experiments is outlined, whose construction will be funded along with the facility. The Facility design permits expansion and evolution, as may be driven by future science requirements, and enables participation by other agencies. The design leverages South Dakota's substantial investment in facility infrastructure, risk retirement, and operation of its Sanford Laboratory at Homestake. The Project is planning education and outreach programs, and has initiated efforts to establish regional partnerships with underserved populations - regional American Indian and rural populations.

Published
2017

27. Control of post-hemorrhoidectomy symptoms and wound healing by Triclosan: a randomized, double-blind, controlled trial

Author

Giannini, I., Pecorella, G., Pennisi, D., Santangelo, G., Digennaro, R., Latorre, F., Giuliani, G., and Donato Francesco Altomare

Subjects
Emorroidectomia, Adult, Hemorrhoidectomy, Male, Wound Healing, Adolescent, Middle Aged, Hemorrhoids, Triclosan, hemorrhoidectomy, Young Adult, Postoperative Complications, Double-Blind Method, Anti-Infective Agents, Local, Humans, Female, Prospective Studies, Aged
Abstract

Milligan-Morgan hemorrhoidectomy (MM) is still the most common treatment for grades III and IV hemorrhoids despite prolonged post-operative anal pain and wound healing. This multicenter, double blind, randomized, controlled trial was designed to assess the safety and the efficacy of anal wound cleansing with Triclosan (Proctocid®) in the control of symptoms and healing time after MM.A total of 113 patients with grades III and IV hemorrhoids, undergoing open hemorroidectomy by diathermy or Ligasure vessel sealing device, were randomly assigned to Triclosan or sodium hypochlorite solution. All patients received analgesics and a fiber-rich diet after hemorrhoidectomy. Postoperative anal pain, bleeding and/or secretion and itch were assessed 7, 14 and 21 days after hemorrhoidectomy by a Visual Analogue Scale (VAS) and the day of complete re-epithelialization of anal wounds was recorded.Fifty-five patients were randomized for Triclosan treatment and 58 for the control drug. The two groups were comparable for demographics, severity of hemorrhoids and technique used for the hemorrhoidectomy. The comparison of days to get complete anal wound healing shows a trend of significance (P=0.05) for the Triclosan group. Bleeding and/or secretion, anal pain and itch were significantly better (P=0.003; P0.0001 and P=0.01, respectively).Triclosan solution for the treatment of post-hemorrhoidectomy wounds is safe and improves the control of post-operative symptoms and wound healing time compared to sodium hypochlorite.

Published
2014

30. An Integral Field Spectrograph for SNAP Supernova Identification

Author

Ealet, A., Prieto, E., Bonissent, A., Malina, R., Bernstein, G., Basa, S., Lefevre, O., Mazure, A., Bonneville, C., Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bester, M., Bower, C., Carithers, W., Commins, E., Day, C., Deustua, S., Digennaro, R., Ellis, R., Eriksson, M., Fruchter, A., Genat, J. F., Goldhaber, G., Goobar, A., Groom, Donald E., Harris, S., Harvey, P., Heetderks, H., Holland, S., Huterer, D., Karcher, A., Kim, A., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Lampton, M., Levi, M., Levin, D., Linder, E., Loken, S., Massey, R., Mckay, T., Mckee, S., Ramon Miquel, Mortsell, E., Mostek, N., Mufson, Stuart L., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Refregier, A., Rhodes, J., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, George F., Spadafora, A., Tarle, G., Tomasch, A., Lippe, H., Vincent, D., Walder, J. P., Wang, G., Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), John C. Mather, Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], [SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph], Astrophysics (astro-ph), FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, Astrophysics, Astrophysics::Galaxy Astrophysics
Abstract

A well-adapted spectrograph concept has been developed for the SNAP (SuperNova/Acceleration Probe) experiment. The goal is to ensure proper identification of Type Ia supernovae and to standardize the magnitude of each candidate by determining explosion parameters. An instrument based on an integral field method with the powerful concept of imager slicing has been designed and is presented in this paper. The spectrograph concept is optimized to have very high efficiency and low spectral resolution (R~100), constant through the wavelength range (0.35-1.7 microns), adapted to the scientific goals of the mission., Comment: This paper will be published in SPIE Proceedings Vol. 4850 and is made available as an electronic preprint with permission of SPIE. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited

Published
2002
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31. The SNAP near infrared detectors

Author

Gregory Tarlé, Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bernstein, G., Bester, M., Bonissent, A., Bower, C., Carithers, W., Commins, E. D., Day, C., Deustua, S., Digennaro, R., Ealet, Anne, Ellis, R. S., Eriksson, M., Fruchter, A., Genat, J. -F, Goldhaber, G., Goobar, A., Groom, D., Harris, S., Harvey, P., Heetderks, H., Holland, S., Huterer, D., Karcher, A., Kim, A., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Lampton, M., Levi, M. E., Levin, D., Linder, E., Loken, S., Malina, R., Massey, R., Miguel, R., Mckay, T., Mckee, S., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Refregier, A., Rhodes, J., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Tomasch, A., Lippe, H., Vincent, R., Walder, J., and Wang, G.

Subjects
Physics
Published
2002

32. Wide-Field Surveys from the SNAP Mission

Author

Kim, Alex G., primary, Akerlof, Carl W., additional, Aldering, Greg, additional, Amanullah, R., additional, Astier, Pierre, additional, Barrelet, E., additional, Bebek, Christopher, additional, Bergstrom, Lars, additional, Bercovitz, J., additional, Bernstein, Gary M., additional, Bester, M., additional, Bonissent, A., additional, Bower, C., additional, Carithers, Jr., William C., additional, Commins, Eugene D., additional, Day, C., additional, Deustua, Susana E., additional, DiGennaro, R., additional, Ealet, A., additional, Ellis, Richard S., additional, Eriksson, M., additional, Fruchter, Andrew, additional, Genat, Jean-Francois, additional, Goldhaber, Gerson, additional, Goobar, Ariel, additional, Groom, Donald E., additional, Harris, Stewart E., additional, Harvey, Peter R., additional, Heetderks, Henry D., additional, Holland, Steven E., additional, Huterer, Dragan, additional, Karcher, Armin, additional, Kolbe, William F., additional, Krieger, B., additional, Lafever, Robin E., additional, Lamoureux, J., additional, Lampton, Michael L., additional, Levi, Michael E., additional, Levin, Daniel S., additional, Linder, Eric V., additional, Loken, Stewart C., additional, Malina, Roger, additional, Massey, R., additional, McKay, Timothy, additional, McKee, Shawn P., additional, Miquel, Ramon, additional, Mortsell, E., additional, Mostek, N., additional, Mufson, Stuart, additional, Musser, J. A., additional, Nugent, Peter E., additional, Oluseyi, Hakeem M., additional, Pain, Reynald, additional, Palaio, Nicholas P., additional, Pankow, David H., additional, Perlmutter, Saul, additional, Pratt, R., additional, Prieto, Eric, additional, Refregier, Alexandre, additional, Rhodes, Jason, additional, Robinson, Kem E., additional, Roe, N., additional, Sholl, Michael, additional, Schubnell, Michael S., additional, Smadja, G., additional, Smoot, George F., additional, Spadafora, Anthony, additional, Tarle, Gregory, additional, Tomasch, Andrew D., additional, von der Lippe, H., additional, Vincent, D., additional, Walder, J.-P., additional, and Wang, Guobin, additional

Published
2002
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33. Ion-source and low-energy beam-transport issues with the front-end systems for the spallation neutron source

Author

Keller, R., primary, Cheng, D., additional, DiGennaro, R., additional, Gough, R. A., additional, Greer, J., additional, Leung, K. N., additional, Ratti, A., additional, Reijonen, J., additional, Thomae, R. W., additional, Schenkel, T., additional, Staples, J. W., additional, Yourd, R., additional, Aleksandrov, A., additional, Stockli, M. P., additional, and Welton, R. W., additional

Published
2002
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36. The LBL 55-meter spherical grating monochromator at SSRL

Author

McKinney, W.R., primary, Howells, M.R., additional, Lauritzen, T., additional, Chin, J., additional, DiGennaro, R., additional, Fong, E., additional, Gath, W., additional, Guigli, J., additional, Hogrefe, H., additional, Meneghetti, J., additional, Plate, D., additional, Heimann, P.A., additional, Terminello, L., additional, Ji, Z., additional, Shirley, D., additional, and Senf, F., additional

Published
1990
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37. Coherent Radiation for X-Ray Imaging—The Soft X-Ray Undulator and the X1A Beamline at the NSLS

Author

Rarback, H., primary, Buckley, C., additional, Ade, H., additional, Camilo, F., additional, DiGennaro, R., additional, Hellman, S., additional, Howells, M., additional, Iskander, N., additional, Jacobsen, C., additional, Kirz, J., additional, Krinsky, S., additional, Lindaas, S., additional, McNulty, I., additional, Oversluizen, M., additional, Rothman, S., additional, Sayre, D., additional, Sharnoff, M., additional, and Shu, D., additional

Published
1990
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38. Multilayer mirrors as power filters in insertion device beamlines.

Author

Kortright, J. B. and DiGennaro, R. S.

Subjects
*MIRRORS, *SYNCHROTRON radiation sources
Abstract

The power-filtering capabilities of multilayer bandpass x-ray mirrors relative to total reflection low-pass mirrors are presented. Results are based on calculations assuming proposed wiggler sources on the upcoming generation of low-energy ( 1.5 GeV) and high-energy ( 7.0 GeV) synchrotron radiation sources. Results show that multilayers outperform total reflection mirrors in terms of reduction in reflected power by roughly an order of magnitude, with relatively small increases in total absorbed power and power density over total reflection mirrors, and with comparable reflected flux values. Various aspects of this potential application of multilayer x-ray optics are discussed. [ABSTRACT FROM AUTHOR]

Published
1989
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39. Soft-x-ray imaging with the 35 period undulator at the NSLS.

Author

Buckley, C., Rarback, H., Alforque, R., Shu, D., Ade, H., Hellman, S., Iskander, N., Kirz, J., Lindaas, S., Mcnulty, I., Oversluizen, M., Tang, E., Attwood, D., DiGennaro, R., Howells, M., Jacobsen, C., Vladimirsky, Y., Rothman, S., and Kern, D.

Subjects
SYNCHROTRONS, WIGGLER magnets, GRENZ rays
Abstract

In the summer of 1988, the National Synchrotron Light Source installed a 35 period soft-x-ray undulator. We are using this device as a radiation source for a beamline designed for soft-x-ray imaging experiments that require high brightness for practical operation. We present the design philosophy and implementation of this beamline. Preliminary characterization of the beamline and undulator indicate that the central intensity of the andulator is within a factor of 2 of design. We have measured an intensity of more than 10[sup 15] photons/s/0.1% BW/mrad² at 36 Å. The monochromator has achieved its design resolving power of 2000. [ABSTRACT FROM AUTHOR]

Published
1989
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40. The little things.

Author

DiGennaro, R.

Subjects
*MEN'S clothing
Abstract

Looks at some quality men's shirts, ties and shoes. How accessories add a quality touch to fashion. Gives designers' names and prices.

Published
1988

41. Weak Lensing from Space I: Instrumentation and Survey Strategy

Author

Rhodes, Jason, Refregier, Alexandre, Massey, Richard, Albert, Justin, Bacon, David, Bernstein, Gary, Ellis, Richard, Jain, Bhuvnesh, Kim, Alex, Lampton, Mike, Mckay, Tim, Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bester, M., Bonissent, A., Bower, C., Carithers, W., Commins, E., Day, C., Deustua, S., Digennaro, R., Ealet, A., Eriksson, M., Fruchter, A., Genat, J. -F, Goldhaber, G., Goobar, A., Groom, D., Harris, S., Harvey, P., Heetderks, H., Holland, S., Huterer, D., Karcher, A., Kolbe, W., Kreiger, B., Lafever, R., Lamoureux, J., Levi, M., Devin, D., Linder, E., Loken, S., Malina, R., Mckee, S., Miquel, R., Mortsell, E., Mostek, N., Mufson, S., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, G., Spadafora, A., Gregory Tarlé, Tomasch, A., Lippe, H., Vincent, D., Walder, J. -P, and Wang, G.

Subjects
Astrophysics::Instrumentation and Methods for Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, gravitational lensing SNAP
Abstract

A wide field space-based imaging telescope is necessary to fully exploit the technique of observing dark matter via weak gravitational lensing. This first paper in a three part series outlines the survey strategies and relevant instrumental parameters for such a mission. As a concrete example of hardware design, we consider the proposed Supernova/Acceleration Probe (SNAP). Using SNAP engineering models, we quantify the major contributions to this telescope's Point Spread Function (PSF). These PSF contributions are relevant to any similar wide field space telescope. We further show that the PSF of SNAP or a similar telescope will be smaller than current ground-based PSFs, and more isotropic and stable over time than the PSF of the Hubble Space Telescope. We outline survey strategies for two different regimes - a "wide" 300 square degree survey and a "deep" 15 square degree survey that will accomplish various weak lensing goals including statistical studies and dark matter mapping.

42. The SNAP Telescope

Author

Lampton, M., Akerlof, C., Aldering, G., Amanullah, R., Astier, P., Barrelet, E., Bebek, C., Bergstrom, L., Bercovitz, J., Bernstein, G., Bester, M., Bonissent, A., Bower, C., Carithers, W., Commins, E., Day, C., Deustua, S., Digennaro, R., Ealet, A., Ellis, R., Eriksson, M., Fruchter, A., Genat, J-F, Goldhaber, G., Goobar, A., Groom, Donald E., Harris, S., Harvey, P., Heetderks, H., Holland, S., Huterer, D., Karcher, A., Kim, A., Kolbe, W., Krieger, B., Lafever, R., Lamoureux, J., Levi, M., Levin, D., Linder, E., Loken, S., Malina, R., Massey, R., Mckay, T., Mckee, S., Ramon Miquel, Mortsell, E., Mostek, N., Mufson, Stuart L., Musser, J., Nugent, P., Oluseyi, H., Pain, R., Palaio, N., Pankow, D., Perlmutter, S., Pratt, R., Prieto, E., Refregier, A., Rhodes, J., Robinson, K., Roe, N., Sholl, M., Schubnell, M., Smadja, G., Smoot, George F., Spadafora, A., Tarle, G., Tomasch, A., Lippe, H., Vincent, R., Walder, J-P, and Wang, G.

43. The fabrication and initial testing of the SNS RFQ

Author

Ratti, A., primary, DiGennaro, R., additional, Gough, R.A., additional, Hoff, M., additional, Keller, R., additional, Kennedy, K., additional, MacGill, R., additional, Staples, J.W., additional, Virostek, S., additional, and Yourd, R., additional

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44. Progress with the SNS front-end systems

Author

Keller, R., primary, Abraham, W., additional, Ayers, J.J., additional, Cheng, D.W., additional, Cull, P., additional, DiGennaro, R., additional, Doolittle, L., additional, Gough, R.A., additional, Greer, J.B., additional, Hoff, M.D., additional, Leung, K.N., additional, Lewis, S., additional, Lionberger, C., additional, MacGill, R., additional, Minamihara, Y., additional, Monroy, M., additional, Oshatz, D., additional, Pruyn, J., additional, Ratti, A., additional, Reijonen, J., additional, Schenkel, T., additional, Staples, J.W., additional, Syversrud, D., additional, Thomae, R., additional, Virostek, S., additional, and Yourd, R., additional

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46. Laparoscopic adjustable gastric banding migration: an early approach for a late complication.

Author

Martines G, Picciariello A, Ugenti I, Lagovardou E, Digennaro R, and Capuano P

Subjects
Follow-Up Studies, Gastroplasty methods, Humans, Time Factors, Foreign-Body Migration surgery, Gastroplasty instrumentation, Laparoscopy, Postoperative Complications surgery, Stomach
Abstract

Aim: Laparoscopic adjustable gastric banding (LAGB) migration is an uncommon late complication after bariatric surgery. It usually presents with an unexplained weight increase or without any symptom. Current guidelines do not establish the timing of a clear endoscopic follow-up to prevent and/or to treat this kind of complication., Patients and Methods: Long-term follow-up was performed in 217 patients with LAGB (37 underwent surgery in other bariatric centers). At the endoscopic check, 3 patients presented banding erosion respectively 7, 9 and 11 years after surgery. In all three cases the patients, lost at the follow-up in their bariatric centers, had weight gain. During the endoscopy was treated just one patient because of the advanced migration. For the other patients, with a minimal migration, the choice was to perform an endoscopic surveillance every 4 months., Discussion: Removal of eroded gastric banding with common endoscopic devices is feasible, safe, and effective., Conclusion: With our experience we suggest to perform planned endoscopy at least within 2 years in order to guarantee the early diagnosis and managing of gastric banding erosion.

Published
2017
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47. Human microRNA expression in sporadic and FAP-associated desmoid tumors and correlation with beta-catenin mutations.

Author

Cavallini A, Rotelli MT, Lippolis C, Piscitelli D, Digennaro R, Covelli C, Carella N, Accetturo M, and Altomare DF

Subjects
Abdominal Neoplasms metabolism, Abdominal Neoplasms pathology, Adenomatous Polyposis Coli metabolism, Adenomatous Polyposis Coli pathology, Adolescent, Adult, Aged, DNA Mutational Analysis, Female, Fibromatosis, Aggressive metabolism, Fibromatosis, Aggressive pathology, Gene Expression Profiling, Genes, APC, Humans, Immunohistochemistry, Male, Middle Aged, RNA Interference, RNA, Messenger genetics, Serpins genetics, Tetraspanins genetics, Transcriptome, Tumor Burden, Young Adult, beta Catenin metabolism, Abdominal Neoplasms genetics, Adenomatous Polyposis Coli genetics, Fibromatosis, Aggressive genetics, Gene Expression Regulation, Neoplastic, MicroRNAs genetics, Mutation, beta Catenin genetics
Abstract

Desmoid tumors (DT) are rare, benign, fibroblastic neoplasm with challenging histological diagnosis. DTs can occur sporadically or associated with the familial adenomatous polyposis coli (FAP). Most sporadic DTs are associated with β-catenin gene (CTNNB1) mutations, while mutated APC gene causes FAP disease. microRNAs (miRNAs) are involved in many human carcinogenesis.The miRNA profile was analyzed by microarray in formalin-fixed, paraffin-embedded (FFPE) specimens of 12 patients (8 sporadic, 4 FAP-associated) and 4 healthy controls. One hundred and one mRNAs resulted dysregulated, of which 98 in sporadic DTs and 8 in FAP-associated DTs, 5 were shared by both tumors. Twenty-six miRNAs were then validated by RT-qPCR in 23 sporadic and 7 FAP-associated DT samples matched with healthy controls. The qPCR method was also used to evaluate the CTNNB1 mutational status in sporadic DTs. The correlation between sporadic DTs and miRNA expression showed that miR-21-3p increased in mutated versus wild-type DTs, while miR-197-3p was decreased. The mRNA expression of Tetraspanin3 and Serpin family A member 3, as miR-21-3p targets, and L1 Cell Adhesion Molecule, as miR-197-3p target, was also evaluate. CTNNB1 mutations associated to miRNA dysregulation could affect the genesis and the progression of this disease and help histological diagnosis of sporadic DTs.

Published
2017
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48. Cyanoacrylate sealant compared to fibrin glue in staple line reinforcement during laparoscopic sleeve gastrectomy. Pilot prospective observational study.

Author

Martines G, Digennaro R, De Fazio M, and Capuano P

Subjects
Adult, Aged, Female, Humans, Male, Middle Aged, Pilot Projects, Prospective Studies, Young Adult, Cyanoacrylates, Fibrin Tissue Adhesive, Gastrectomy methods, Laparoscopy, Surgical Stapling, Tissue Adhesives
Abstract

Laparoscopic Sleeve Gastrectomy (LSG) is associated with serious complications, such as staple line leaks and bleeding. This paper presents a novel approach aimed at the successful consolidation of the suture by the use of the cyanoacrylate, here compared to the use of fibrin glue. Fifty consecutive patients, recruited from October 2015 to March 2016, were submitted to laparoscopic sleeve gastrectomy by standardized surgical technique. The staple line was reinforced with cyanoacrylate or fibrin glue. There were no post-operative complications and no operative time prolongation. An early removal of the draining and a reduction of the average hospitalization were observed. The results suggest that staple line reinforcement with cyanoacrylate during laparoscopic sleeve gastrectomy is as easy, safe and cost-saving as with fibrin glue. Furthermore, cyanocrilate allows a chemical omentoplasty with the result of restoring the anatomy. Therefore, this approach is viable and useful for future trials on the efficacy in preventing surgical post-operative complications.

Published
2017
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49. Coloanal anastomosis or abdominoperineal resection for very low rectal cancer: what will benefit, the surgeon's pride or the patient's quality of life?

Author

Digennaro R, Tondo M, Cuccia F, Giannini I, Pezzolla F, Rinaldi M, Scala D, Romano G, and Altomare DF

Subjects
Adult, Aged, Aged, 80 and over, Anastomosis, Surgical, Fecal Incontinence etiology, Female, Humans, Male, Middle Aged, Rectal Neoplasms complications, Surveys and Questionnaires, Urinary Incontinence etiology, Abdomen surgery, Anal Canal surgery, Colon surgery, Perineum surgery, Physicians, Quality of Life, Rectal Neoplasms surgery
Abstract

Purposes: Sphincter-saving operation with coloanal anastomosis (CAA) has become an established option for very low rectal cancer, but few studies have compared its functional results and quality of life (QoL) with abdominoperineal resection (APR) showing controversial results., Patients and Methods: Patients treated for low rectal cancer with APR or CAA, disease-free after a median follow-up period of 26.5 (8-84) and 52.5 (12-156) months, respectively, were retrospectively reviewed. General and disease-specific changes in QoL and severity of disease were evaluated by Karnofsky scale, EORTC-C30, EORTC-CR38, SF-36, PGWBI, FIQL, PAC-QoL, ICIQ-SF, Stoma-QoL, AMS, Wexner's score and obstructed defecation syndrome (ODS) score., Results: Twenty-six APR patients and 34 CAA patients entered the study. Karnofsky score did not show significant differences. The median Stoma-QoL was 58.2 (45-76.6), indicating a good stoma function in 95% of patients. EORTC-C30, CR38, PGWBI and SF-36 questionnaires did not show significant differences between the two groups except for sexual function (better after CAA, p = 0.01). Eleven patients after APR and eight after CAA had urinary incontinence, and its severity did not differ significantly. Eighteen of 21 CAA patients complained of faecal incontinence [AMS, 80 (15-120); Wexner, 13 (2-19)] with an impact on their QoL [FIQL: lifestyle, 1.75 (0-4); coping/behaviour, 1.3 (0-3.5); depression, 2.1 (0-5.2); embarrassment, 2 (0-4.6)] and 11 complained of obstructed defecation [7.5 (3-16)] with significant consequences on QoL [PAC-QoL, 30.4 (19.2-80.3)]., Conclusions: QoL in patients with permanent stoma and in those after CAA did not differ significantly. APR patients had worse sexual function, while most CAA patients had faecal incontinence and sometime obstructed defecation, with important impact on their QoL.

Published
2013
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