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1. AutArch: An AI-assisted workflow for object detection and automated recording in archaeological catalogues

Author

Klein, Kevin, Wohde, Alyssa, Gorelik, Alexander V., Heyd, Volker, Lämmel, Ralf, Diekmann, Yoan, and Brami, Maxime

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Graphics, Computer Science - Machine Learning
Abstract

The context of this paper is the creation of large uniform archaeological datasets from heterogeneous published resources, such as find catalogues - with the help of AI and Big Data. The paper is concerned with the challenge of consistent assemblages of archaeological data. We cannot simply combine existing records, as they differ in terms of quality and recording standards. Thus, records have to be recreated from published archaeological illustrations. This is only a viable path with the help of automation. The contribution of this paper is a new workflow for collecting data from archaeological find catalogues available as legacy resources, such as archaeological drawings and photographs in large unsorted PDF files; the workflow relies on custom software (AutArch) supporting image processing, object detection, and interactive means of validating and adjusting automatically retrieved data. We integrate artificial intelligence (AI) in terms of neural networks for object detection and classification into the workflow, thereby speeding up, automating, and standardising data collection. Objects commonly found in archaeological catalogues - such as graves, skeletons, ceramics, ornaments, stone tools and maps - are detected. Those objects are spatially related and analysed to extract real-life attributes, such as the size and orientation of graves based on the north arrow and the scale. We also automate recording of geometric whole-outlines through contour detection, as an alternative to landmark-based geometric morphometrics. Detected objects, contours, and other automatically retrieved data can be manually validated and adjusted. We use third millennium BC Europe (encompassing cultures such as 'Corded Ware' and 'Bell Beaker', and their burial practices) as a 'testing ground' and for evaluation purposes; this includes a user study for the workflow and the AutArch software.

Published
2023

6. Dairying, diseases and the evolution of lactase persistence in Europe

Author

Evershed, Richard P., Davey Smith, George, Roffet-Salque, Mélanie, Timpson, Adrian, Diekmann, Yoan, Lyon, Matthew S., Cramp, Lucy J. E., Casanova, Emmanuelle, Smyth, Jessica, Whelton, Helen L., Dunne, Julie, Brychova, Veronika, Šoberl, Lucija, Gerbault, Pascale, Gillis, Rosalind E., Heyd, Volker, Johnson, Emily, Kendall, Iain, Manning, Katie, Marciniak, Arkadiusz, Outram, Alan K., Vigne, Jean-Denis, Shennan, Stephen, Bevan, Andrew, Colledge, Sue, Allason-Jones, Lyndsay, Amkreutz, Luc, Anders, Alexandra, Arbogast, Rose-Marie, Bălăşescu, Adrian, Bánffy, Eszter, Barclay, Alistair, Behrens, Anja, Bogucki, Peter, Carrancho Alonso, Ángel, Carretero, José Miguel, Cavanagh, Nigel, Claßen, Erich, Collado Giraldo, Hipolito, Conrad, Matthias, Csengeri, Piroska, Czerniak, Lech, Dębiec, Maciej, Denaire, Anthony, Domboróczki, László, Donald, Christina, Ebert, Julia, Evans, Christopher, Francés-Negro, Marta, Gronenborn, Detlef, Haack, Fabian, Halle, Matthias, Hamon, Caroline, Hülshoff, Roman, Ilett, Michael, Iriarte, Eneko, Jakucs, János, Jeunesse, Christian, Johnson, Melanie, Jones, Andy M., Karul, Necmi, Kiosak, Dmytro, Kotova, Nadezhda, Krause, Rüdiger, Kretschmer, Saskia, Krüger, Marta, Lefranc, Philippe, Lelong, Olivia, Lenneis, Eva, Logvin, Andrey, Lüth, Friedrich, Marton, Tibor, Marley, Jane, Mortimer, Richard, Oosterbeek, Luiz, Oross, Krisztián, Pavúk, Juraj, Pechtl, Joachim, Pétrequin, Pierre, Pollard, Joshua, Pollard, Richard, Powlesland, Dominic, Pyzel, Joanna, Raczky, Pál, Richardson, Andrew, Rowe, Peter, Rowland, Stephen, Rowlandson, Ian, Saile, Thomas, Sebők, Katalin, Schier, Wolfram, Schmalfuß, Germo, Sharapova, Svetlana, Sharp, Helen, Sheridan, Alison, Shevnina, Irina, Sobkowiak-Tabaka, Iwona, Stadler, Peter, Stäuble, Harald, Stobbe, Astrid, Stojanovski, Darko, Tasić, Nenad, van Wijk, Ivo, Vostrovská, Ivana, Vuković, Jasna, Wolfram, Sabine, Zeeb-Lanz, Andrea, and Thomas, Mark G.

Published
2022
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8. The genomic origins of the world’s first farmers

Author

Marchi, Nina, Winkelbach, Laura, Schulz, Ilektra, Brami, Maxime, Hofmanová, Zuzana, Blöcher, Jens, Reyna-Blanco, Carlos S., Diekmann, Yoan, Thiéry, Alexandre, Kapopoulou, Adamandia, Link, Vivian, Piuz, Valérie, Kreutzer, Susanne, Figarska, Sylwia M., Ganiatsou, Elissavet, Pukaj, Albert, Struck, Travis J., Gutenkunst, Ryan N., Karul, Necmi, Gerritsen, Fokke, Pechtl, Joachim, Peters, Joris, Zeeb-Lanz, Andrea, Lenneis, Eva, Teschler-Nicola, Maria, Triantaphyllou, Sevasti, Stefanović, Sofija, Papageorgopoulou, Christina, Wegmann, Daniel, Burger, Joachim, and Excoffier, Laurent

Published
2022
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9. Author Correction: Dairying, diseases and the evolution of lactase persistence in Europe

Author

Evershed, Richard P., Davey Smith, George, Roffet-Salque, Mélanie, Timpson, Adrian, Diekmann, Yoan, Lyon, Matthew S., Cramp, Lucy J. E., Casanova, Emmanuelle, Smyth, Jessica, Whelton, Helen L., Dunne, Julie, Brychova, Veronika, Šoberl, Lucija, Gerbault, Pascale, Gillis, Rosalind E., Heyd, Volker, Johnson, Emily, Kendall, Iain, Manning, Katie, Marciniak, Arkadiusz, Outram, Alan K., Vigne, Jean-Denis, Shennan, Stephen, Bevan, Andrew, Colledge, Sue, Allason-Jones, Lyndsay, Amkreutz, Luc, Anders, Alexandra, Arbogast, Rose-Marie, Bălăşescu, Adrian, Bánffy, Eszter, Barclay, Alistair, Behrens, Anja, Bogucki, Peter, Carrancho Alonso, Ángel, Carretero, José Miguel, Cavanagh, Nigel, Claßen, Erich, Collado Giraldo, Hipolito, Conrad, Matthias, Csengeri, Piroska, Czerniak, Lech, Dębiec, Maciej, Denaire, Anthony, Domboróczki, László, Donald, Christina, Ebert, Julia, Evans, Christopher, Francés-Negro, Marta, Gronenborn, Detlef, Haack, Fabian, Halle, Matthias, Hamon, Caroline, Hülshoff, Roman, Ilett, Michael, Iriarte, Eneko, Jakucs, János, Jeunesse, Christian, Johnson, Melanie, Jones, Andy M., Karul, Necmi, Kiosak, Dmytro, Kotova, Nadezhda, Krause, Rüdiger, Kretschmer, Saskia, Krüger, Marta, Lefranc, Philippe, Lelong, Olivia, Lenneis, Eva, Logvin, Andrey, Lüth, Friedrich, Marton, Tibor, Marley, Jane, Mortimer, Richard, Oosterbeek, Luiz, Oross, Krisztián, Pavúk, Juraj, Pechtl, Joachim, Pétrequin, Pierre, Pollard, Joshua, Pollard, Richard, Powlesland, Dominic, Pyzel, Joanna, Raczky, Pál, Richardson, Andrew, Rowe, Peter, Rowland, Stephen, Rowlandson, Ian, Saile, Thomas, Sebők, Katalin, Schier, Wolfram, Schmalfuß, Germo, Sharapova, Svetlana, Sharp, Helen, Sheridan, Alison, Shevnina, Irina, Sobkowiak-Tabaka, Iwona, Stadler, Peter, Stäuble, Harald, Stobbe, Astrid, Stojanovski, Darko, Tasić, Nenad, van Wijk, Ivo, Vostrovská, Ivana, Vuković, Jasna, Wolfram, Sabine, Zeeb-Lanz, Andrea, and Thomas, Mark G.

Published
2022
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10. Identifying Maximal Perfect Haplotype Blocks

Author

Cunha, Luís, Diekmann, Yoan, Kowada, Luis, Stoye, Jens, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, and Alves, Ronnie, editor

Published
2018
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11. Ancient genomes indicate population replacement in Early Neolithic Britain

Author

Brace, Selina, Diekmann, Yoan, Booth, Thomas J., van Dorp, Lucy, Faltyskova, Zuzana, Rohland, Nadin, Mallick, Swapan, Olalde, Iñigo, Ferry, Matthew, Michel, Megan, Oppenheimer, Jonas, Broomandkhoshbacht, Nasreen, Stewardson, Kristin, Martiniano, Rui, Walsh, Susan, Kayser, Manfred, Charlton, Sophy, Hellenthal, Garrett, Armit, Ian, Schulting, Rick, Craig, Oliver E., Sheridan, Alison, Parker Pearson, Mike, Stringer, Chris, Reich, David, Thomas, Mark G., and Barnes, Ian

Published
2019
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13. Descent, marriage, and residence practices of a 3,800-year-old pastoral community in Central Eurasia

Author

Blöcher, Jens, primary, Brami, Maxime, additional, Feinauer, Isabelle Sofie, additional, Stolarczyk, Eliza, additional, Diekmann, Yoan, additional, Vetterdietz, Lisa, additional, Karapetian, Marina, additional, Winkelbach, Laura, additional, Kokot, Vanessa, additional, Vallini, Leonardo, additional, Stobbe, Astrid, additional, Haak, Wolfgang, additional, Papageorgopoulou, Christina, additional, Krause, Rüdiger, additional, Sharapova, Svetlana, additional, and Burger, Joachim, additional

Published
2023
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14. Early Neolithic genomes from the eastern Fertile Crescent

Author

Broushaki, Farnaz, Thomas, Mark G., Link, Vivian, López, Saioa, van Dorp, Lucy, Kirsanow, Karola, Hofmanová, Zuzana, Diekmann, Yoan, Cassidy, Lara M., Díez-del-Molino, David, Kousathanas, Athanasios, Sell, Christian, Robson, Harry K., Martiniano, Rui, Blöcher, Jens, Scheu, Amelie, Kreutzer, Susanne, Bollongino, Ruth, Bobo, Dean, Davoudi, Hossein, Munoz, Olivia, Currat, Mathias, Abdi, Kamyar, Biglari, Fereidoun, Craig, Oliver E., Bradley, Daniel G., Shennan, Stephen, Veeramah, Krishna R., Mashkour, Marjan, Wegmann, Daniel, Hellenthal, Garrett, and Burger, Joachim

Published
2016

15. Early farmers from across Europe directly descended from Neolithic Aegeans

Author

Hofmanová, Zuzana, Kreutzer, Susanne, Hellenthal, Garrett, Sell, Christian, Diekmann, Yoan, Díez-del-Molino, David, van Dorp, Lucy, López, Saioa, Kousathanas, Athanasios, Link, Vivian, Kirsanow, Karola, Cassidy, Lara M., Martiniano, Rui, Strobel, Melanie, Scheu, Amelie, Kotsakis, Kostas, Halstead, Paul, Triantaphyllou, Sevi, Kyparissi-Apostolika, Nina, Urem-Kotsou, Dushka, Ziota, Christina, Adaktylou, Fotini, Gopalan, Shyamalika, Bobo, Dean M., Winkelbach, Laura, Blöcher, Jens, Unterländer, Martina, Leuenberger, Christoph, Çilingiroğlu, Çiler, Horejs, Barbara, Gerritsen, Fokke, Shennan, Stephen J., Bradley, Daniel G., Currat, Mathias, Veeramah, Krishna R., Wegmann, Daniel, Thomas, Mark G., Papageorgopoulou, Christina, and Burger, Joachim

Published
2016

16. Descent, marriage, and residence practices of a 3,800-year-old pastoral community in Central Eurasia

Author

Blöcher, Jens, Brami, Maxime, Feinauer, Isabelle Sofie, Stolarczyk, Eliza, Diekmann, Yoan, Vetterdietz, Lisa, Karapetian, Marina, Winkelbach, Laura, Kokot, Vanessa, Vallini, Leonardo, Stobbe, Astrid, Haak, Wolfgang, Papageorgopoulou, Christina, Krause, Rüdiger, Sharapova, Svetlana, Burger, Joachim, Blöcher, Jens, Brami, Maxime, Feinauer, Isabelle Sofie, Stolarczyk, Eliza, Diekmann, Yoan, Vetterdietz, Lisa, Karapetian, Marina, Winkelbach, Laura, Kokot, Vanessa, Vallini, Leonardo, Stobbe, Astrid, Haak, Wolfgang, Papageorgopoulou, Christina, Krause, Rüdiger, Sharapova, Svetlana, and Burger, Joachim

Abstract

Our understanding of prehistoric societal organization at the family level is still limited. Here, we generated genome data from 32 individuals from an approximately 3,800-y-old burial mound attributed to the Bronze Age Srubnaya-Alakul cultural tradition at the site of Nepluyevsky, located in the Southern Ural region of Central Eurasia. We found that life expectancy was generally very low, with adult males living on average 8 y longer than females. A total of 35 first-degree, 40 second-degree, and 48 third-degree biological relationships connected 23 of the studied individuals, allowing us to propose a family tree spanning three generations with six brothers at its center. The oldest of these brothers had eight children with two women and the most children overall, whereas the other relationships were monogamous. Notably, related female children above the age of five were completely absent from the site, and adult females were more genetically diverse than males. These results suggest that biological relationships between male siblings played a structural role in society and that descent group membership was based on patrilineality. Women originated from a larger mating network and moved to join the men, with whom they were buried. Finally, the oldest brother likely held a higher social position, which was expressed in terms of fertility.

Published
2023
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19. Author Correction: Ancient genomes indicate population replacement in Early Neolithic Britain

Author

Brace, Selina, Diekmann, Yoan, Booth, Thomas J., van Dorp, Lucy, Faltyskova, Zuzana, Rohland, Nadin, Mallick, Swapan, Olalde, Iñigo, Ferry, Matthew, Michel, Megan, Oppenheimer, Jonas, Broomandkhoshbacht, Nasreen, Stewardson, Kristin, Martiniano, Rui, Walsh, Susan, Kayser, Manfred, Charlton, Sophy, Hellenthal, Garrett, Armit, Ian, Schulting, Rick, Craig, Oliver E., Sheridan, Alison, Pearson, Mike Parker, Stringer, Chris, Reich, David, Thomas, Mark G., and Barnes, Ian

Published
2019
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23. Increased Population Risk of AIP‐Related Acromegaly and Gigantism in Ireland

Author

Radian, Serban, Diekmann, Yoan, Gabrovska, Plamena, Holland, Brendan, Bradley, Lisa, Wallace, Helen, Stals, Karen, Bussell, Anna‐Marie, McGurren, Karen, Cuesta, Martin, Ryan, Anthony W., Herincs, Maria, Hernández‐Ramírez, Laura C., Holland, Aidan, Samuels, Jade, Aflorei, Elena Daniela, Barry, Sayka, Dénes, Judit, Pernicova, Ida, Stiles, Craig E., Trivellin, Giampaolo, McCloskey, Ronan, Ajzensztejn, Michal, Abid, Noina, Akker, Scott A., Mercado, Moises, Cohen, Mark, Thakker, Rajesh V., Baldeweg, Stephanie, Barkan, Ariel, Musat, Madalina, Levy, Miles, Orme, Stephen M., Unterländer, Martina, Burger, Joachim, Kumar, Ajith V., Ellard, Sian, McPartlin, Joseph, McManus, Ross, Linden, Gerard J., Atkinson, Brew, Balding, David J., Agha, Amar, Thompson, Chris J., Hunter, Steven J., Thomas, Mark G., Morrison, Patrick J., and Korbonits, Márta

Published
2017
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24. The Beaker phenomenon and the genomic transformation of northwest Europe

Author

Olalde, Iigo, Brace, Selina, Allentoft, Morten E., Armit, Ian, Kristiansen, Kristian, Booth, Thomas, Rohland, Nadin, Mallick, Swapan, Szcsnyi-Nagy, Anna, Mittnik, Alissa, Altena, Eveline, Lipson, Mark, Lazaridis, Iosif, Harper, Thomas K., Patterson, Nick, Broomandkhoshbacht, Nasreen, Diekmann, Yoan, Faltyskova, Zuzana, Fernandes, Daniel, Ferry, Matthew, Harney, Eadaoin, de Knijff, Peter, Michel, Megan, Oppenheimer, Jonas, Stewardson, Kristin, Barclay, Alistair, Alt, Kurt Werner, Liesau, Corina, Ros, Patricia, Blasco, Concepcin, Miguel, Jorge Vega, Garca, Roberto Menduia, Fernndez, Azucena Avils, Bnffy, Eszter, Bernab-Brea, Maria, Billoin, David, Bonsall, Clive, Bonsall, Laura, Allen, Tim, Bster, Lindsey, Carver, Sophie, Navarro, Laura Castells, Craig, Oliver E., Cook, Gordon T., Cunliffe, Barry, Denaire, Anthony, Dinwiddy, Kirsten Egging, Dodwell, Natasha, Erne, Michal, Evans, Christopher, Kucha?ík, Milan, Farr, Joan Francs, Fowler, Chris, Gazenbeek, Michiel, Pena, Rafael Garrido, Haber-Uriarte, Mara, Haduch, El?bieta, Hey, Gill, Jowett, Nick, Knowles, Timothy, Massy, Ken, Pfrengle, Saskia, Lefranc, Philippe, Lemercier, Olivier, Lefebvre, Arnaud, Martnez, Csar Heras, Olmo, Virginia Galera, Ramrez, Ana Bastida, Maurandi, Joaqun Lomba, Maj, Tona, McKinley, Jacqueline I., McSweeney, Kathleen, Mende, Balzs Gusztv, Mod, Alessandra, Kulcsr, Gabriella, Kiss, Viktria, Czene, Andrs, Patay, Rbert, Endr?di, Anna, Khler, Kitti, Hajdu, Tams, Szeniczey, Tams, Dani, Jnos, Bernert, Zsolt, Hoole, Maya, Cheronet, Olivia, Keating, Denise, Velemnsk, Petr, Dobe, Miroslav, Candilio, Francesca, Brown, Fraser, Fernndez, Ral Flores, Herrero-Corral, Ana-Mercedes, Tusa, Sebastiano, Carnieri, Emiliano, Lentini, Luigi, Valenti, Antonella, Zanini, Alessandro, Waddington, Clive, Delibes, Germn, Guerra-Doce, Elisa, Neil, Benjamin, Brittain, Marcus, Luke, Mike, Mortimer, Richard, Desideri, Jocelyne, Besse, Marie, Brcken, Gnter, Furmanek, Mirosaw, Hauszko, Agata, Mackiewicz, Maksym, Rapi?ski, Artur, Leach, Stephany, Soriano, Ignacio, Lillios, Katina T., Cardoso, Joo Lus, Pearson, Michael Parker, Wodarczak, Piotr, Price, T. Douglas, Prieto, Pilar, Rey, Pierre-Jrme, Risch, Roberto, Rojo Guerra, Manuel A., Schmitt, Aurore, Serralongue, Jol, Silva, Ana Maria, Smr?ka, Vclav, Vergnaud, Luc, Zilho, Joo, Caramelli, David, Higham, Thomas, Thomas, Mark G., Kennett, Douglas J., Fokkens, Harry, Heyd, Volker, Sheridan, Alison, Sjgren, Karl-Gran, Stockhammer, Philipp W., Krause, Johannes, Pinhasi, Ron, Haak, Wolfgang, Barnes, Ian, Lalueza-Fox, Carles, and Reich, David

Subjects
Research, Genetic aspects, Europeans -- Genetic aspects, Genetic transformation -- Research, Genomics -- Research
Abstract

Author(s): Iigo Olalde (corresponding author) [1]; Selina Brace [2]; Morten E. Allentoft [3]; Ian Armit [4]; Kristian Kristiansen [5]; Thomas Booth [2]; Nadin Rohland [1]; Swapan Mallick [1, 6, 7]; [...], From around 2750 to 2500 bc, Bell Beaker pottery became widespread across western and central Europe, before it disappeared between 2200 and 1800 bc. The forces that propelled its expansion are a matter of long-standing debate, and there is support for both cultural diffusion and migration having a role in this process. Here we present genome-wide data from 400 Neolithic, Copper Age and Bronze Age Europeans, including 226 individuals associated with Beaker-complex artefacts. We detected limited genetic affinity between Beaker-complex-associated individuals from Iberia and central Europe, and thus exclude migration as an important mechanism of spread between these two regions. However, migration had a key role in the further dissemination of the Beaker complex. We document this phenomenon most clearly in Britain, where the spread of the Beaker complex introduced high levels of steppe-related ancestry and was associated with the replacement of approximately 90% of Britains gene pool within a few hundred years, continuing the east-to-west expansion that had brought steppe-related ancestry into central and northern Europe over the previous centuries.

Published
2018
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27. Low Prevalence of Lactase Persistence in Bronze Age Europe Indicates Ongoing Strong Selection over the Last 3,000 Years

Author

Burger, Joachim, Link, Vivian, Blöcher, Jens, Schulz, Anna, Sell, Christian, Pochon, Zoé, Diekmann, Yoan, Žegarac, Aleksandra, Hofmanová, Zuzana, Winkelbach, Laura, Reyna-Blanco, Carlos S., Bieker, Vanessa, Orschiedt, Jörg, Brinker, Ute, Scheu, Amelie, Leuenberger, Christoph, Bertino, Thomas S., Bollongino, Ruth, Lidke, Gundula, Stefanović, Sofija, Jantzen, Detlef, Kaiser, Elke, Terberger, Thomas, Thomas, Mark G., Veeramah, Krishna R., and Wegmann, Daniel

Published
2020
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28. Ancient genomes provide insights into family structure and the heredity of social status in the early Bronze Age of southeastern Europe

Author

Žegarac Aleksandra, Winkelbach Laura, Blöcher Jens, Diekmann Yoan, Krečković Gavrilović Marija, Porčić Marko, Stojković Biljana, Milašinović Lidija, Schreiber Mona, Wegmann Daniel, Veeramah Krishna, Stefanović Sofija, and Burger Joachim

Subjects
Adult, Male, Heredity, Adolescent, Science, Human Migration, 930 History of ancient world, Young Adult, 930 Alte Geschichte, Early Bronze Age, Humans, Mokrin, Child, ancient DNA, kinship, History, Ancient, Genome, Human, Middle Aged, Prognosis, Survival Rate, Genetics, Population, Psychological Distance, Social Class, Child, Preschool, Medicine, Female, Family Relations, Follow-Up Studies
Abstract

Twenty-four palaeogenomes from Mokrin, a major Early Bronze Age necropolis in southeastern Europe, were sequenced to analyse kinship between individuals and to better understand prehistoric social organization. 15 investigated individuals were involved in genetic relationships of varying degrees. The Mokrin sample resembles a genetically unstructured population, suggesting that the community’s social hierarchies were not accompanied by strict marriage barriers. We find evidence for female exogamy but no indications for strict patrilocality. Individual status differences at Mokrin, as indicated by grave goods, support the inference that females could inherit status, but could not transmit status to all their sons. We further show that sons had the possibility to acquire status during their lifetimes, but not necessarily to inherit it. Taken together, these findings suggest that Southeastern Europe in the Early Bronze Age had a significantly different family and social structure than Late Neolithic and Early Bronze Age societies of Central Europe.

Published
2020

29. Biological Kinship and Inheritance of Social Status in the Early Bronze Age: Paleogenetic Analysis of the Mokrin Necropolis in Serbia

Author

Žegarac, Aleksandra, Winkelbach, Laura, Diekmann, Yoan, Krečković Gavrilović, Marija, Porčić, Marko, Stojković, Biljana, Veeramah, Krishna R, Burger, Joachim, and Stefanović, Sofija

Subjects
aDNA, social organization, Early Bronze Age, Mokrin, Maros culture
Abstract

The Early Bronze Age necropolis of Mokrin in Serbia (2100-1800 cal BC), which belongs to Maros culture, has a great significance for the study of kinship relationships and social organization. As the other necropolises of the Maros culture, Mokrin had a highly standardized funerary ritual: the deceased were laid to rest in a couched position, arms bent at the elbows and facing east, while the position of the skeletons depended on the sex. The graves were equipped with various burial objects - from simple ceramics to golden jewellery, and previous studies have identified weapons and certain types of jewellery as status markers. Graves of the children followed the burial rituals of the adults and had similar grave goods. Since the Early Bronze Age is a period of great social change, the study of biological kinship can be crucial when it comes to determining whether wealth and social status were inherited or achieved. By analysing the ancient genomic data of 24 individuals (14 adults and 10 children) from the Mokrin necropolis, we were able to identify nine family relationships. The analysis of biological relationships, together with anthropological (age and sex) and archaeological data (variation in the number and quality of grave goods), suggest that status was probably not inherited by male children, as it was previously observed in other Bronze Age societies. With this study, we show that the inheritance of social status does not necessarily have to follow universal patterns, but may well show regional variations. This study also represents a stepping stone for future research of the social transformations in the Early Bronze Age of Balkans and Europe.&nbsp

Published
2020
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30. Ancient genomes provide insights into family structure and the heredity of social status in the early Bronze Age of southeastern Europe

Author

Žegarac, Aleksandra, Winkelbach, L., Bloecher, J., Diekmann, Yoan, Krečković Gavrilović, Marija, Porčić, Marko, Stojković, B., Milašinović, Lidija, Schreiber, M., Wegmann, D., Veeramah, Krishna R., Stefanović, Sofija, Burger, Joachim, Žegarac, Aleksandra, Winkelbach, L., Bloecher, J., Diekmann, Yoan, Krečković Gavrilović, Marija, Porčić, Marko, Stojković, B., Milašinović, Lidija, Schreiber, M., Wegmann, D., Veeramah, Krishna R., Stefanović, Sofija, and Burger, Joachim

Abstract

Twenty-four palaeogenomes from Mokrin, a major Early Bronze Age necropolis in southeastern Europe, were sequenced to analyse kinship between individuals and to better understand prehistoric social organization. 15 investigated individuals were involved in genetic relationships of varying degrees. The Mokrin sample resembles a genetically unstructured population, suggesting that the community's social hierarchies were not accompanied by strict marriage barriers. We find evidence for female exogamy but no indications for strict patrilocality. Individual status differences at Mokrin, as indicated by grave goods, support the inference that females could inherit status, but could not transmit status to all their sons. We further show that sons had the possibility to acquire status during their lifetimes, but not necessarily to inherit it. Taken together, these findings suggest that Southeastern Europe in the Early Bronze Age had a significantly different family and social structure than Late Neolithic and Early Bronze Age societies of Central Europe.

Published
2021

31. Demogenomic modeling of the timing and the processes of early European farmers differentiation

Author

Marchi, Nina, primary, Winkelbach, Laura, additional, Schulz, Ilektra, additional, Brami, Maxime, additional, Hofmanová, Zuzana, additional, Blöcher, Jens, additional, Reyna-Blanco, Carlos S., additional, Diekmann, Yoan, additional, Thiéry, Alexandre, additional, Kapopoulou, Adamandia, additional, Link, Vivian, additional, Piuz, Valérie, additional, Kreutzer, Susanne, additional, Figarska, Sylwia M., additional, Ganiatsou, Elissavet, additional, Pukaj, Albert, additional, Struck, Travis J., additional, Gutenkunst, Ryan N., additional, Karul, Necmi, additional, Gerritsen, Fokke, additional, Pechtl, Joachim, additional, Peters, Joris, additional, Zeeb-Lanz, Andrea, additional, Lenneis, Eva, additional, Teschler-Nicola, Maria, additional, Triantaphyllou, Sevasti, additional, Stefanović, Sofija, additional, Papageorgopoulou, Christina, additional, Wegmann, Daniel, additional, Burger, Joachim, additional, and Excoffier, Laurent, additional

Published
2020
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32. XAF1 as a modifier of p53 function and cancer susceptibility

Author

Pinto, Emilia M., primary, Figueiredo, Bonald C., additional, Chen, Wenan, additional, Galvao, Henrique C.R., additional, Formiga, Maria Nirvana, additional, Fragoso, Maria Candida B.V., additional, Ashton-Prolla, Patricia, additional, Ribeiro, Enilze M.S.F., additional, Felix, Gabriela, additional, Costa, Tatiana E.B., additional, Savage, Sharon A., additional, Yeager, Meredith, additional, Palmero, Edenir I., additional, Volc, Sahlua, additional, Salvador, Hector, additional, Fuster-Soler, Jose Luis, additional, Lavarino, Cinzia, additional, Chantada, Guillermo, additional, Vaur, Dominique, additional, Odone-Filho, Vicente, additional, Brugières, Laurence, additional, Else, Tobias, additional, Stoffel, Elena M., additional, Maxwell, Kara N., additional, Achatz, Maria Isabel, additional, Kowalski, Luis, additional, de Andrade, Kelvin C., additional, Pappo, Alberto, additional, Letouze, Eric, additional, Latronico, Ana Claudia, additional, Mendonca, Berenice B., additional, Almeida, Madson Q., additional, Brondani, Vania B., additional, Bittar, Camila M., additional, Soares, Emerson W.S., additional, Mathias, Carolina, additional, Ramos, Cintia R.N., additional, Machado, Moara, additional, Zhou, Weiyin, additional, Jones, Kristine, additional, Vogt, Aurelie, additional, Klincha, Payal P., additional, Santiago, Karina M., additional, Komechen, Heloisa, additional, Paraizo, Mariana M., additional, Parise, Ivy Z.S., additional, Hamilton, Kayla V., additional, Wang, Jinling, additional, Rampersaud, Evadnie, additional, Clay, Michael R., additional, Murphy, Andrew J., additional, Lalli, Enzo, additional, Nichols, Kim E., additional, Ribeiro, Raul C., additional, Rodriguez-Galindo, Carlos, additional, Korbonits, Marta, additional, Zhang, Jinghui, additional, Thomas, Mark G., additional, Connelly, Jon P., additional, Pruett-Miller, Shondra, additional, Diekmann, Yoan, additional, Neale, Geoffrey, additional, Wu, Gang, additional, and Zambetti, Gerard P., additional

Published
2020
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33. Kinship, acquired and inherited status, and population structure at the Early Bronze Age Mokrin necropolis in northern Serbia

Author

Žegarac, Aleksandra, primary, Winkelbach, Laura, additional, Blöcher, Jens, additional, Diekmann, Yoan, additional, Gavrilović, Marija Krečković, additional, Porčić, Marko, additional, Stojković, Biljana, additional, Milašinović, Lidija, additional, Schreiber, Mona, additional, Wegmann, Daniel, additional, Veeramah, Krishna R., additional, Stefanović, Sofija, additional, and Burger, Joachim, additional

Published
2020
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34. Avelines's Hole: An Unexpected Twist in the Tale

Author

Schulting, Rick J., Booth, Tom, Brace, Selina, Diekmann, Yoan, Thomas, Mark, Barnes, Ian, Meiklejohn, Chris, Babb, Jeff, Budd, Chelsea, Charlton, Sophy, Van Der Plicht, Hans, Mullan, Graham, and Wilson, Linda

Subjects
Burrington Combe, Aveline's Hole, Mesolithic period -- Somerset, Cemeteries -- England
Abstract

Aveline’s Hole is the largest known Early Mesolithic cemetery in Britain, previously thought to have no evidence for subsequent burial activity. Thus, it came as some surprise when the results of a recent ancient human DNA study found that, of four individuals from the site yielding genomic data, two showed high levels of ancestry from Early Neolithic Aegean farmers. Radiocarbon dating confirmed that these two individuals were indeed British Early Neolithic in date, while the other two had the expected ‘Western Hunter-Gatherer’ ancestry genomic signatures, with the two groups separated in time by nearly five millennia. Moreover, the two Neolithic samples were both crania, while the two Mesolithic samples were long bones. Given the absence of Neolithic dates in the previous sizeable dating programme combined with the difficult history of the collection, i.e., the WWII bombing of its Bristol repository, this raised the question of whether the crania might in fact be from another site. As we show in this paper, a very strong case can be made that the crania do in fact originate from Aveline’s Hole. Additional radiocarbon dating (14 in total, including the above mentioned four) suggests that about half the cranial elements from the site fall within the Early Neolithic, though there is still no evidence for the deposition of post-cranial remains at this time, nor is there any burial evidence in the long intervening period between the Early Mesolithic and the Early Neolithic. Intriguingly, craniometric analyses of legacy data including three crania lost in the bombing suggest that one, Aveline’s Hole ‘A’, may be Upper Palaeolithicin date. As part of this re-investigation of the human remains from the site, we present new stable carbon and nitrogen isotope analyses that differ significantly from those originally reported for the Early Mesolithic, with the new results more in keeping with other isotopic data for this period. We also present new stable carbon and nitrogen isotope results on human remains from the nearby Early Mesolithic sites of Badger Hole and Greylake, and report new Early Mesolithic radiocarbon dates and isotopic data from Cannington Park Quarry. Clear isotopic differences between the Early Mesolithic and the Neolithic remains can be seen, but these are argued to relate primarily to shifts in the underlying ecological baselines, rather than to differences in types of foods consumed (with the caveat that terrestrial wild and domesticated foods will be isotopically similar). The genetic data are summarised, giving evidence not only of the ancestry of Mesolithic and Neolithic individuals from Aveline’s Hole, but also suggesting something of their physical appearance. The degree of population replacement now indicated by ancient DNA suggests that there was a substantial migration of farmers into Britain at the start of the Neolithic. This new information demonstrates the archaeological importance of Aveline's Hole for both the Mesolithic and Neolithic periods. "Funding for nine of the new radiocarbon dates from Aveline’s Hole reported here was provided by NERC’s NRCF programme (NF/2016/2/16). The ancient DNA study was funded by the Wellcome Trust (100713/Z/12/Z), as were three new radiocarbon dates from Aveline’s Hole. The isotopic analysis of the Badger Hole human remains was funded as part of a NERC studentship (NE/K500987/1)." https://www.ubss.org.uk/resources/proceedings/vol28/UBSS_Proc_28_1_9-63.pdf

Published
2019

35. Genomic Data from an Ancient European Battlefield Indicates On-Going Strong Selection on a Genomic Region Associated with Lactase Persistence Over the Last 3,000 Years

Author

Burger, Joachim, primary, Link, Vivian, additional, Blöcher, Jens, additional, Schulz, Anna, additional, Sell, Christian, additional, Pochon, Zoé, additional, Diekmann, Yoan, additional, Zegarac, Aleksandra, additional, Hofmanová, Zuzana, additional, Winkelbach, Laura, additional, Reyna-Blanco, Carlos S., additional, Bieker, Vanessa, additional, Orschiedt, Jörg, additional, Brinker, Ute, additional, Scheu, Amelie, additional, Bollongino, Ruth, additional, Lidke, Gundula, additional, Stefanovic, Sofija, additional, Jantzen, Detlef, additional, Kaiser, Elke, additional, Terberger, Thomas, additional, Thomas, Mark G., additional, Veeramah, Krishna R., additional, and Wegmann, Daniel, additional

Published
2020
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36. Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

Author

Fumagalli, Matteo, primary, Camus, Stephane M, additional, Diekmann, Yoan, additional, Burke, Alice, additional, Camus, Marine D, additional, Norman, Paul J, additional, Joseph, Agnel, additional, Abi-Rached, Laurent, additional, Benazzo, Andrea, additional, Rasteiro, Rita, additional, Mathieson, Iain, additional, Topf, Maya, additional, Parham, Peter, additional, Thomas, Mark G, additional, and Brodsky, Frances M, additional

Published
2019
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38. Erratum: The Beaker phenomenon and the genomic transformation of northwest Europe

Author

Olalde, Iigo, Brace, Selina, Allentoft, Morten E., Armit, Ian, Kristiansen, Kristian, Booth, Thomas, Rohland, Nadin, Mallick, Swapan, Szcsnyi-Nagy, Anna, Mittnik, Alissa, Altena, Eveline, Lipson, Mark, Lazaridis, Iosif, Harper, Thomas K., Patterson, Nick, Broomandkhoshbacht, Nasreen, Diekmann, Yoan, Faltyskova, Zuzana, Fernandes, Daniel, Ferry, Matthew, Harney, Eadaoin, de Knijff, Peter, Michel, Megan, Oppenheimer, Jonas, Stewardson, Kristin, Barclay, Alistair, Alt, Kurt Werner, Liesau, Corina, Ros, Patricia, Blasco, Concepcin, Miguel, Jorge Vega, Garca, Roberto Menduia, Fernndez, Azucena Avils, Bnffy, Eszter, Bernab-Brea, Maria, Billoin, David, Bonsall, Clive, Bonsall, Laura, Allen, Tim, Bster, Lindsey, Carver, Sophie, Navarro, Laura Castells, Craig, Oliver E., Cook, Gordon T., Cunliffe, Barry, Denaire, Anthony, Dinwiddy, Kirsten Egging, Dodwell, Natasha, Erne, Michal, Evans, Christopher, Kuchak, Milan, Farr, Joan Francs, Fowler, Chris, Gazenbeek, Michiel, Pena, Rafael Garrido, Haber-Uriarte, Mara, Haduch, Elbieta, Hey, Gill, Jowett, Nick, Knowles, Timothy, Massy, Ken, Pfrengle, Saskia, Lefranc, Philippe, Lemercier, Olivier, Lefebvre, Arnaud, Martnez, Csar Heras, Olmo, Virginia Galera, Ramrez, Ana Bastida, Maurandi, Joaqun Lomba, Maj, Tona, McKinley, Jacqueline I., McSweeney, Kathleen, Mende, Balzs Gusztv, Modi, Alessandra, Kulcsr, Gabriella, Kiss, Viktria, Czene, Andrs, Patay, Rbert, Endrdi, Anna, Khler, Kitti, Hajdu, Tams, Szeniczey, Tams, Dani, Jnos, Bernert, Zsolt, Hoole, Maya, Cheronet, Olivia, Keating, Denise, Velemnsk, Petr, Dobe, Miroslav, Candilio, Francesca, Brown, Fraser, Fernndez, Ral Flores, Herrero-Corral, Ana-Mercedes, Tusa, Sebastiano, Carnieri, Emiliano, Lentini, Luigi, Valenti, Antonella, Zanini, Alessandro, Waddington, Clive, Delibes, Germn, Guerra-Doce, Elisa, Neil, Benjamin, Brittain, Marcus, Luke, Mike, Mortimer, Richard, Desideri, Jocelyne, Besse, Marie, Brcken, Gnter, Furmanek, Mirosaw, Hauszko, Agata, Mackiewicz, Maksym, Rapiski, Artur, Leach, Stephany, Soriano, Ignacio, Lillios, Katina T., Cardoso, Joo Lus, Pearson, Michael Parker, Wodarczak, Piotr, Price, T. Douglas, Prieto, Pilar, Rey, Pierre-Jrme, Risch, Roberto, Guerra, Manuel A. Rojo, Schmitt, Aurore, Serralongue, Jol, Silva, Ana Maria, Smrka, Vclav, Vergnaud, Luc, Zilho, Joo, Caramelli, David, Higham, Thomas, Thomas, Mark G., Kennett, Douglas J., Fokkens, Harry, Heyd, Volker, Sheridan, Alison, Sjgren, Karl-Gran, Stockhammer, Philipp W., Krause, Johannes, Pinhasi, Ron, Haak, Wolfgang, Barnes, Ian, Lalueza-Fox, Carles, and Reich, David

Abstract

Author(s): Iigo Olalde; Selina Brace; Morten E. Allentoft; Ian Armit; Kristian Kristiansen; Thomas Booth; Nadin Rohland; Swapan Mallick; Anna Szcsnyi-Nagy; Alissa Mittnik; Eveline Altena; Mark Lipson; Iosif Lazaridis; Thomas K. [...]

Published
2018
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39. Author response: Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

Author

Fumagalli, Matteo, primary, Camus, Stephane M, additional, Diekmann, Yoan, additional, Burke, Alice, additional, Camus, Marine D, additional, Norman, Paul J, additional, Joseph, Agnel, additional, Abi-Rached, Laurent, additional, Benazzo, Andrea, additional, Rasteiro, Rita, additional, Mathieson, Iain, additional, Topf, Maya, additional, Parham, Peter, additional, Thomas, Mark G, additional, and Brodsky, Frances M, additional

Published
2019
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40. ‘Ava’: a Beaker-associated woman from a cist at Achavanich, Highland, and the story of her (re-)discovery and subsequent study

Author

Hoole, Maya, primary, Sheridan, Alison, primary, Boyle, Angela, primary, Booth, Thomas, primary, Brace, Selina, primary, Diekmann, Yoan, primary, Olalde, Iñigo, primary, Thomas, Mark G, primary, Barnes, Ian, primary, Evans, Jane, primary, Chenery, Carolyn, primary, Sloane, Hilary, primary, Morrison, Hew, primary, Fraser, Sheena, primary, Timpany, Scott, primary, and Hamilton, Derek, primary

Published
2018
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41. Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

Author

Fumagalli, Matteo, primary, Camus, Stephane M., additional, Diekmann, Yoan, additional, Burke, Alice, additional, Camus, Marine D., additional, Norman, Paul J., additional, Joseph, Agnel Praveen, additional, Abi-Rached, Laurent, additional, Benazzo, Andrea, additional, Rasteiro, Rita, additional, Mathieson, Iain, additional, Topf, Maya, additional, Parham, Peter, additional, Thomas, Mark G., additional, and Brodsky, Frances M., additional

Published
2018
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42. The Beaker phenomenon and the genomic transformation of northwest Europe

Author

Olalde, Iñigo, Brace, Selina, Allentoft, Morten E., Armit, Ian, Kristiansen, Kristian, Booth, Thomas, Rohland, Nadin, Mallick, Swapan, Szécsényi-nagy, Anna, Mittnik, Alissa, Altena, Eveline, Lipson, Mark, Lazaridis, Iosif, Harper, Thomas K., Patterson, Nick, Broomandkhoshbacht, Nasreen, Diekmann, Yoan, Faltyskova, Zuzana, Fernandes, Daniel, Ferry, Matthew, Harney, Eadaoin, De Knijff, Peter, Michel, Megan, Oppenheimer, Jonas, Stewardson, Kristin, Barclay, Alistair, Alt, Kurt Werner, Liesau, Corina, Ríos, Patricia, Blasco, Concepción, Miguel, Jorge Vega, García, Roberto Menduiña, Fernández, Azucena Avilés, Bánffy, Eszter, Bernabò-brea, Maria, Billoin, David, Bonsall, Clive, Bonsall, Laura, Allen, Tim, Büster, Lindsey, Carver, Sophie, Navarro, Laura Castells, Craig, Oliver E., Cook, Gordon T., Cunliffe, Barry, Denaire, Anthony, Dinwiddy, Kirsten Egging, Dodwell, Natasha, Ernée, Michal, Evans, Christopher, Kuchařík, Milan, Farré, Joan Francès, Fowler, Chris, Gazenbeek, Michiel, Pena, Rafael Garrido, Haber-uriarte, María, Haduch, Elżbieta, Hey, Gill, Jowett, Nick, Knowles, Timothy, Massy, Ken, Pfrengle, Saskia, Lefranc, Philippe, Lemercier, Olivier, Lefebvre, Arnaud, Martínez, César Heras, Olmo, Virginia Galera, Ramírez, Ana Bastida, Maurandi, Joaquín Lomba, Majó, Tona, Mckinley, Jacqueline I., Mcsweeney, Kathleen, Mende, Balázs Gusztáv, Mod, Alessandra, Kulcsár, Gabriella, Kiss, Viktória, Czene, András, Patay, Róbert, Endrődi, Anna, Köhler, Kitti, Hajdu, Tamás, Szeniczey, Tamás, Dani, János, Bernert, Zsolt, Hoole, Maya, Cheronet, Olivia, Keating, Denise, Velemínský, Petr, Dobeš, Miroslav, Candilio, Francesca, Brown, Fraser, Fernández, Raúl Flores, Herrero-corral, Ana-mercedes, Tusa, Sebastiano, Carnieri, Emiliano, Lentini, Luigi, Valenti, Antonella, Zanini, Alessandro, Waddington, Clive, Delibes, Germán, Guerra-doce, Elisa, Neil, Benjamin, Brittain, Marcus, Luke, Mike, Mortimer, Richard, Desideri, Jocelyne, Besse, Marie, Brücken, Günter, Furmanek, Mirosław, Hałuszko, Agata, Mackiewicz, Maksym, Rapiński, Artur, Leach, Stephany, Soriano, Ignacio, Lillios, Katina T., Cardoso, João Luís, Pearson, Michael Parker, Włodarczak, Piotr, Price, T. Douglas, Prieto, Pilar, Rey, Pierre-jérôme, Risch, Roberto, Rojo Guerra, Manuel A., Schmitt, Aurore, Serralongue, Joël, Silva, Ana Maria, Smrčka, Václav, Vergnaud, Luc, Zilhão, João, Caramelli, David, Higham, Thomas, Thomas, Mark G., Kennett, Douglas J., Fokkens, Harry, Heyd, Volker, Sheridan, Alison, Sjögren, Karl-göran, Stockhammer, Philipp W., Krause, Johannes, Pinhasi, Ron, Haak, Wolfgang, Barnes, Ian, Lalueza-fox, Carles, Reich, David, Olalde, Iñigo, Brace, Selina, Allentoft, Morten E., Armit, Ian, Kristiansen, Kristian, Booth, Thomas, Rohland, Nadin, Mallick, Swapan, Szécsényi-nagy, Anna, Mittnik, Alissa, Altena, Eveline, Lipson, Mark, Lazaridis, Iosif, Harper, Thomas K., Patterson, Nick, Broomandkhoshbacht, Nasreen, Diekmann, Yoan, Faltyskova, Zuzana, Fernandes, Daniel, Ferry, Matthew, Harney, Eadaoin, De Knijff, Peter, Michel, Megan, Oppenheimer, Jonas, Stewardson, Kristin, Barclay, Alistair, Alt, Kurt Werner, Liesau, Corina, Ríos, Patricia, Blasco, Concepción, Miguel, Jorge Vega, García, Roberto Menduiña, Fernández, Azucena Avilés, Bánffy, Eszter, Bernabò-brea, Maria, Billoin, David, Bonsall, Clive, Bonsall, Laura, Allen, Tim, Büster, Lindsey, Carver, Sophie, Navarro, Laura Castells, Craig, Oliver E., Cook, Gordon T., Cunliffe, Barry, Denaire, Anthony, Dinwiddy, Kirsten Egging, Dodwell, Natasha, Ernée, Michal, Evans, Christopher, Kuchařík, Milan, Farré, Joan Francès, Fowler, Chris, Gazenbeek, Michiel, Pena, Rafael Garrido, Haber-uriarte, María, Haduch, Elżbieta, Hey, Gill, Jowett, Nick, Knowles, Timothy, Massy, Ken, Pfrengle, Saskia, Lefranc, Philippe, Lemercier, Olivier, Lefebvre, Arnaud, Martínez, César Heras, Olmo, Virginia Galera, Ramírez, Ana Bastida, Maurandi, Joaquín Lomba, Majó, Tona, Mckinley, Jacqueline I., Mcsweeney, Kathleen, Mende, Balázs Gusztáv, Mod, Alessandra, Kulcsár, Gabriella, Kiss, Viktória, Czene, András, Patay, Róbert, Endrődi, Anna, Köhler, Kitti, Hajdu, Tamás, Szeniczey, Tamás, Dani, János, Bernert, Zsolt, Hoole, Maya, Cheronet, Olivia, Keating, Denise, Velemínský, Petr, Dobeš, Miroslav, Candilio, Francesca, Brown, Fraser, Fernández, Raúl Flores, Herrero-corral, Ana-mercedes, Tusa, Sebastiano, Carnieri, Emiliano, Lentini, Luigi, Valenti, Antonella, Zanini, Alessandro, Waddington, Clive, Delibes, Germán, Guerra-doce, Elisa, Neil, Benjamin, Brittain, Marcus, Luke, Mike, Mortimer, Richard, Desideri, Jocelyne, Besse, Marie, Brücken, Günter, Furmanek, Mirosław, Hałuszko, Agata, Mackiewicz, Maksym, Rapiński, Artur, Leach, Stephany, Soriano, Ignacio, Lillios, Katina T., Cardoso, João Luís, Pearson, Michael Parker, Włodarczak, Piotr, Price, T. Douglas, Prieto, Pilar, Rey, Pierre-jérôme, Risch, Roberto, Rojo Guerra, Manuel A., Schmitt, Aurore, Serralongue, Joël, Silva, Ana Maria, Smrčka, Václav, Vergnaud, Luc, Zilhão, João, Caramelli, David, Higham, Thomas, Thomas, Mark G., Kennett, Douglas J., Fokkens, Harry, Heyd, Volker, Sheridan, Alison, Sjögren, Karl-göran, Stockhammer, Philipp W., Krause, Johannes, Pinhasi, Ron, Haak, Wolfgang, Barnes, Ian, Lalueza-fox, Carles, and Reich, David

Published
2018

43. Population Replacement in Early Neolithic Britain

Author

Brace, Selina, primary, Diekmann, Yoan, additional, Booth, Thomas J., additional, Faltyskova, Zuzana, additional, Rohland, Nadin, additional, Mallick, Swapan, additional, Ferry, Matthew, additional, Michel, Megan, additional, Oppenheimer, Jonas, additional, Broomandkhoshbacht, Nasreen, additional, Stewardson, Kristin, additional, Walsh, Susan, additional, Kayser, Manfred, additional, Schulting, Rick, additional, Craig, Oliver E., additional, Sheridan, Alison, additional, Pearson, Mike Parker, additional, Stringer, Chris, additional, Reich, David, additional, Thomas, Mark G., additional, and Barnes, Ian, additional

Published
2018
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44. In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism

Author

Salvatori, Roberto, primary, Radian, Serban, additional, Diekmann, Yoan, additional, Iacovazzo, Donato, additional, David, Alessia, additional, Gabrovska, Plamena, additional, Grassi, Giorgia, additional, Bussell, Anna-Marie, additional, Stals, Karen, additional, Weber, Astrid, additional, Quinton, Richard, additional, Crowne, Elizabeth C, additional, Corazzini, Valentina, additional, Metherell, Lou, additional, Kearney, Tara, additional, Du Plessis, Daniel, additional, Sinha, Ajay Kumar, additional, Baborie, Atik, additional, Lecoq, Anne-Lise, additional, Chanson, Philippe, additional, Ansorge, Olaf, additional, Ellard, Sian, additional, Trainer, Peter J, additional, Balding, David, additional, Thomas, Mark G, additional, and Korbonits, Márta, additional

Published
2017
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45. The Beaker Phenomenon and the Genomic Transformation of Northwest Europe

Author

Olalde, Iñigo, primary, Brace, Selina, additional, Allentoft, Morten E., additional, Armit, Ian, additional, Kristiansen, Kristian, additional, Rohland, Nadin, additional, Mallick, Swapan, additional, Booth, Thomas, additional, Szécsényi-Nagy, Anna, additional, Mittnik, Alissa, additional, Altena, Eveline, additional, Lipson, Mark, additional, Lazaridis, Iosif, additional, Patterson, Nick, additional, Broomandkhoshbacht, Nasreen, additional, Diekmann, Yoan, additional, Faltyskova, Zuzana, additional, Fernandes, Daniel, additional, Ferry, Matthew, additional, Harney, Eadaoin, additional, Knijff, Peter de, additional, Michel, Megan, additional, Oppenheimer, Jonas, additional, Stewardson, Kristin, additional, Barclay, Alistair, additional, Alt, Kurt W., additional, Avilés Fernández, Azucena, additional, Bánffy, Eszter, additional, Bernabò-Brea, Maria, additional, Billoin, David, additional, Blasco, Concepción, additional, Bonsall, Clive, additional, Bonsall, Laura, additional, Allen, Tim, additional, Büster, Lindsey, additional, Carver, Sophie, additional, Navarro, Laura Castells, additional, Craig, Oliver Edward, additional, Cook, Gordon T., additional, Cunliffe, Barry, additional, Denaire, Anthony, additional, Dinwiddy, Kirsten Egging, additional, Dodwell, Natasha, additional, Ernée, Michal, additional, Evans, Christopher, additional, Kuchařík, Milan, additional, Francès Farré, Joan, additional, Fokkens, Harry, additional, Fowler, Chris, additional, Gazenbeek, Michiel, additional, Pena, Rafael Garrido, additional, Haber-Uriarte, María, additional, Haduch, Elżbieta, additional, Hey, Gill, additional, Jowett, Nick, additional, Knowles, Timothy, additional, Massy, Ken, additional, Pfrengle, Saskia, additional, Lefranc, Philippe, additional, Lemercier, Olivier, additional, Lefebvre, Arnaud, additional, Lomba Maurandi, Joaquín, additional, Majó, Tona, additional, McKinley, Jacqueline I., additional, McSweeney, Kathleen, additional, Balázs Gusztáv, Mende, additional, Modi, Alessandra, additional, Kulcsár, Gabriella, additional, Kiss, Viktória, additional, Czene, András, additional, Patay, Róbert, additional, Endrődi, Anna, additional, Köhler, Kitti, additional, Hajdu, Tamás, additional, Cardoso, João Luís, additional, Liesau, Corina, additional, Pearson, Michael Parker, additional, Włodarczak, Piotr, additional, Douglas Price, T., additional, Prieto, Pilar, additional, Rey, Pierre-Jérôme, additional, Ríos, Patricia, additional, Risch, Roberto, additional, Rojo Guerra, Manuel A., additional, Schmitt, Aurore, additional, Serralongue, Joël, additional, Silva, Ana Maria, additional, Smrčka, Václav, additional, Vergnaud, Luc, additional, Zilhão, João, additional, Caramelli, David, additional, Higham, Thomas, additional, Heyd, Volker, additional, Sheridan, Alison, additional, Sjögren, Karl-Göran, additional, Thomas, Mark G., additional, Stockhammer, Philipp W., additional, Pinhasi, Ron, additional, Krause, Johannes, additional, Haak, Wolfgang, additional, Barnes, Ian, additional, Lalueza-Fox, Carles, additional, and Reich, David, additional

Published
2017
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46. The Evolution of Function in the Rab family of Small GTPases

Author

Diekmann, Yoan and Leal, José Pereira

Abstract

Dissertation presented to obtain the PhD degree in Computational Biology. The question how protein function evolves is a fundamental problem with profound implications for both functional end evolutionary studies on proteins. Here, we review some of the work that has addressed or contributed to this question. We identify and comment on three different levels relevant for the evolution of protein function. First, biochemistry. This is the focus of our discussion, as protein function itself commonly receives least attention in studies on protein evolution.(...)

Published
2014

48. Increased Population Risk ofAIP-Related Acromegaly and Gigantism in Ireland

Author

Radian, Serban, primary, Diekmann, Yoan, additional, Gabrovska, Plamena, additional, Holland, Brendan, additional, Bradley, Lisa, additional, Wallace, Helen, additional, Stals, Karen, additional, Bussell, Anna-Marie, additional, McGurren, Karen, additional, Cuesta, Martin, additional, Ryan, Anthony W., additional, Herincs, Maria, additional, Hernández-Ramírez, Laura C., additional, Holland, Aidan, additional, Samuels, Jade, additional, Aflorei, Elena Daniela, additional, Barry, Sayka, additional, Dénes, Judit, additional, Pernicova, Ida, additional, Stiles, Craig E., additional, Trivellin, Giampaolo, additional, McCloskey, Ronan, additional, Ajzensztejn, Michal, additional, Abid, Noina, additional, Akker, Scott A., additional, Mercado, Moises, additional, Cohen, Mark, additional, Thakker, Rajesh V., additional, Baldeweg, Stephanie, additional, Barkan, Ariel, additional, Musat, Madalina, additional, Levy, Miles, additional, Orme, Stephen M., additional, Unterländer, Martina, additional, Burger, Joachim, additional, Kumar, Ajith V., additional, Ellard, Sian, additional, McPartlin, Joseph, additional, McManus, Ross, additional, Linden, Gerard J., additional, Atkinson, Brew, additional, Balding, David J., additional, Agha, Amar, additional, Thompson, Chris J., additional, Hunter, Steven J., additional, Thomas, Mark G., additional, Morrison, Patrick J., additional, and Korbonits, Márta, additional

Published
2016
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49. Early farmers from across Europe directly descended from Neolithic Aegeans

Author

Hofmanová, Zuzana, primary, Kreutzer, Susanne, additional, Hellenthal, Garrett, additional, Sell, Christian, additional, Diekmann, Yoan, additional, Díez del Molino, David, additional, van Dorp, Lucy, additional, López, Saioa, additional, Kousathanas, Athanasios, additional, Link, Vivian, additional, Kirsanow, Karola, additional, Cassidy, Lara M, additional, Martiniano, Rui, additional, Strobel, Melanie, additional, Scheu, Amelie, additional, Kotsakis, Kostas, additional, Halstead, Paul, additional, Triantaphyllou, Sevi, additional, Kyparissi-Apostolika, Nina, additional, Urem-Kotsou, Dushanka-Christina, additional, Ziota, Christina, additional, Adaktylou, Fotini, additional, Gopalan, Shyamalika, additional, Bobo, Dean M, additional, Winkelbach, Laura, additional, Blöcher, Jens, additional, Unterländer, Martina, additional, Leuenberger, Christoph, additional, Çilingiroğlu, Çiler, additional, Horejs, Barbara, additional, Gerritsen, Fokke, additional, Shennan, Stephen, additional, Bradley, Daniel G, additional, Currat, Mathias, additional, Veeramah, Krishna, additional, Wegmann, Daniel, additional, Thomas, Mark G, additional, Papageorgopoulou, Christina, additional, and Burger, Joachim, additional

Published
2015
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50. The founder R304*AIPmutation is prevalent in Irish acromegaly and gigantism patients as well as in the general population of Ireland

Author

Radian, Serban, primary, Diekmann, Yoan, additional, Gabrovska, Plamena, additional, Holland, Brendan, additional, Bradley, Lisa, additional, Wallace, Helen, additional, Stals, Karen, additional, Bussell, Anna-Marie, additional, McGurren, Karen, additional, Cuesta, Martin, additional, Ryan, Anthony W, additional, Herincs, Maria, additional, Hernandez-Ramirez, Laura C, additional, Holland, Aidan, additional, Samuels, Jade, additional, Aflorei, Elena Daniela, additional, Barry, Sayka, additional, Denes, Judit, additional, Pernicova, Ida, additional, Stiles, Craig E, additional, Trivellin, Giampaolo, additional, McCloskey, Ronan, additional, Ajzensztejn, Michal, additional, Abid, Noina, additional, Akker, Scott A, additional, Mercado, Moises, additional, Cohen, Mark, additional, Thakker, Rajesh V, additional, Baldeweg, Stephanie, additional, Barkan, Ariel, additional, Musat, Madalina, additional, Levy, Miles, additional, Orme, Steve, additional, Unterlander, Martina, additional, Burger, Joachim, additional, Kumar, Ajith V, additional, Ellard, Sian, additional, McPartlin, Joseph, additional, McManus, Ross, additional, Linden, Gerard J, additional, Atkinson, Brew, additional, Thomas, Mark G, additional, Balding, David J, additional, Agha, Amar, additional, Thompson, Chris J, additional, Hunter, Steve J, additional, Morrison, Patrick J, additional, and Korbonits, Marta, additional

Published
2015
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