1. Predictors for the Emergence of the 2 Multi-nucleoside/nucleotide Resistance Mutations 69 Insertion and Q151M and their Impact on Clinical Outcome in the Swiss HIV Cohort Study
- Author
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Sabine Yerly, Alexandra U. Scherrer, Thomas Klimkait, Beda Joos, Bruno Ledergerber, Viktor von Wyl, Philippe Bürgisser, Jürg Böni, Huldrych F. Günthard, University of Zurich, Swiss HIV Cohort Study, Battegay, M., Bernasconi, E., Böni, J., Bucher, HC., Bürgisser, P., Calmy, A., Cattacin, S., Cavassini, M., Dubs, R., Egger, M., Elzi, L., Fischer, M., Flepp, M., Fontana, A., Francioli, P., Furrer, H., Fux, CA., Gorgievski, M., Günthard, H., Hirsch, HH., Hirschel, B., Hösli, I., Kahlert, C., Kaiser, L., Karrer, U., Kind, C., Klimkait, T., Ledergerber, B., Martinetti, G., Müller, N., Nadal, D., Paccaud, F., Pantaleo, G., Rauch, A., Regenass, S., Rickenbach, M., Schmid, P., Schultze, D., Schüpbach, J., Speck, R., de Tejada BM., Taffé, P., Telenti, A., Trkola, A., Vernazza, P., Weber, R., and Yerly, S.
- Subjects
10028 Institute of Medical Virology ,HIV Infections ,medicine.disease_cause ,Cohort Studies ,10234 Clinic for Infectious Diseases ,0302 clinical medicine ,Risk Factors ,Cause of Death ,Immunology and Allergy ,030212 general & internal medicine ,Didanosine ,Cause of death ,ddc:616 ,0303 health sciences ,Mutation ,biology ,Mortality rate ,3. Good health ,Treatment Outcome ,Infectious Diseases ,Anti-Retroviral Agents ,Lentivirus ,2723 Immunology and Allergy ,Switzerland ,Cohort study ,medicine.drug ,medicine.medical_specialty ,Anti-HIV Agents/pharmacology ,Anti-Retroviral Agents/pharmacology ,Anti-Retroviral Agents/therapeutic use ,Case-Control Studies ,Didanosine/pharmacology ,Drug Resistance, Multiple, Viral/genetics ,HIV Infections/drug therapy ,HIV Infections/mortality ,HIV-1/drug effects ,HIV-1/genetics ,Humans ,Logistic Models ,Switzerland/epidemiology ,Anti-HIV Agents ,610 Medicine & health ,Major Articles and Brief Reports ,03 medical and health sciences ,Drug Resistance, Multiple, Viral ,Internal medicine ,medicine ,030306 microbiology ,business.industry ,Case-control study ,2725 Infectious Diseases ,Odds ratio ,biology.organism_classification ,Immunology ,HIV-1 ,570 Life sciences ,business - Abstract
The 69 insertion and Q151M mutations are multi-nucleoside/nucleotide resistance mutations (MNR). The prevalence among 4078 antiretroviral therapy (ART)-experienced individuals was
- Published
- 2011