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4. A Bima Array Survey of Molecules in Comets Linear (C/2002 T7) and Neat (C/2001 Q4)

Author

Remijan, Anthony J., Friedel, D. N., de Pater, Imke, Hogerheijde, M. R., Snyder, L. E., A'Hearn, M. F., Blake, Geoffrey A., Dickel, H. R., Forster, J. R., Kraybill, C., Looney, L. W., Palmer, Patrick, and Wright, M. C. H.

Subjects
Astrophysics
Abstract

We present an interferometric search for large molecules, including methanol, methyl cyanide, ethyl cyanide, ethanol, and methyl formate in comets LINEAR (C/2002 T7) and NEAT (C/2001 Q4) with the Berkeley-Illinois-Maryland Association (BIMA) array. In addition, we also searched for transitions of the simpler molecules CS, SiO, HNC, HN13C and 13CO . We detected transitions of methanol and CS around Comet LINEAR and one transition of methanol around Comet NEAT within a synthesized beam of ~20''. We calculated the total column density and production rate of each molecular species using the variable temperature and outflow velocity (VTOV) model described by Friedel et al.(2005).Considering the molecular production rate ratios with respect to water, Comet T7 LINEAR is more similar to Comet Hale-Bopp while Comet Q4 NEAT is more similar to Comet Hyakutake. It is unclear, however, due to such a small sample size, whether there is a clear distinction between a Hale-Bopp and Hyakutake class of comet or whether comets have a continuous range of molecular production rate ratios., Comment: Accepted for Publication in the Astrophysical Journal

Published
2006
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5. BIMA Array Detections of HCN in Comets LINEAR (C/2002 T7) and NEAT (C/2001 Q4)

Author

Friedel, D. N., Remijan, Anthony J., Snyder, L. E., A'Hearn, M. F., Blake, Geoffrey A., de Pater, Imke, Dickel, H. R., Forster, J. R., Hogerheijde, M. R., Kraybill, C., Looney, L. W., Palmer, Patrick, and Wright, M. C. H.

Subjects
Astrophysics
Abstract

We present interferometric detections of HCN in comets LINEAR (C/2002 T7) and NEAT (C/2001 Q4) with the Berkeley-Illinois-Maryland Association (BIMA) Array. With a 25.4"x20.3" synthesized beam around Comet LINEAR and using a variable temperature and outflow velocity (VTOV) model, we found an HCN column density of N_T=6.4+-2.1x10^12 cm^-2, and a production rate of Q(HCN)=6.5+-2.2x10^26 s^-1, giving a production rate ratio of HCN relative to H_2O of ~3.3+-1.1x10^-3 and relative to CN of ~4.6+-1.5. With a 21.3"x17.5" synthesized beam around Comet NEAT and using a VTOV model, we found an HCN column density of N_T=8.5+-4.5x10^11 cm^-2, and a production rate of Q(HCN)=8.9+-4.7x10^25 s^-1, giving a production rate ratio of HCN relative to H_2O of ~7.4+-3.9x10^-4 and relative to CN of ~0.3+-0.2. For both comets, the production rates relative to H_2O are similar to those found in previous comet observations. For Comet LINEAR the production rate relative to CN is consistent with HCN being the primary parent species of CN, while for Comet NEAT it is too low for this to be the case., Comment: 20 pages, 2 figures, to be published in the Astrophysical Journal

Published
2005
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7. WSRT and VLA Observations of the 6 cm and 2 cm lines of H2CO in the direction of W 58 C1(ON3) and W 58 C2

Author

Dickel, H. R., Goss, W. M., and De Pree, C. G.

Subjects
Astrophysics
Abstract

Absorption in the J{K-K+} = 2{11}-2{12} transition of formaldehyde at 2 cm towards the ultracompact HII regions C1 and C2 of W 58 has been observed with the VLA with an angular resolution of ~0.2'' and a velocity resolution of ~1 km/s. The high resolution continuum image of C1 (ON 3) shows a partial shell which opens to the NE. Strong H2CO absorption is observed against W 58 C1. The highest optical depth (tau > 2) occurs in the SW portion of C1 near the edge of the shell, close to the continuum peak. The absorption is weaker towards the nearby, more diffuse compact HII region C2, tau<~0.3. The H2CO velocity (-21.2 km/s) towards C1 is constant and agrees with the velocity of CO emission, mainline OH masers, and the H76 alpha recombination line, but differs from the velocity of the 1720 MHz OH maser emission (~-13 km/s). Observations of the absorption in the J{K-K+} = 1{10}-1{11} transition of formaldehyde at 6 cm towards W 58 C1 and C2 carried out earlier with the WSRT at lower resolution (~4''x7'') show comparable optical depths and velocities to those observed at 2 cm. Based on the mean optical depth profiles at 6 cm and 2 cm, the volume density of molecular hydrogen n(H2) and the formaldehyde column density N(H2CO) were determined. The n(H2) is ~6E4 /cm**3 towards C1. N(H2CO) for C1 is ~8E14 /cm**2 while that towards C2 is ~8E13 /cm**2., Comment: AJ in press Jan 2001, 14 pages plus 6 figures (but Fig. 1 has 4 separate parts, a through d). Data are available at http://adil.ncsa.uiuc.edu/document/00.HD.01

Published
2000
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8. Allergologische Diagnostik von Überempfindlichkeitsreaktionen auf Arzneimittel

Author

Brockow, K., primary, Wurpts, G., additional, Trautmann, A., additional, Pfützner, W., additional, Treudler, R., additional, Bircher, A.J., additional, Brehler, R., additional, Buhl, T., additional, Dickel, H., additional, Fuchs, T., additional, Jakob, T., additional, Kurz, J., additional, Kreft, B., additional, Lange, L., additional, Merk, H.F., additional, Mockenhaupt, M., additional, Mülleneisen, N., additional, Ott, H., additional, Ring, J., additional, Ruëff, F., additional, Sachs, B., additional, Sitter, H., additional, Wedi, B., additional, Wöhrl, S., additional, Worm, M., additional, and Zuberbier, T., additional

Published
2023
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12. „Frühjahr-Sommer-Herbst-Ekzem“ einer Floristin

Author

Dickel, H., Leiste, A., Tran, D.H., Stücker, M., and Altmeyer, P.

Abstract

Zusammenfassung: Eine Kompositenallergie bei Floristen ist zumeist beruflich verursacht. Mit aerogener Auslösung ist die Schwere der Hauterkrankung gegeben und die Aufgabe der Tätigkeit objektiv medizinisch geboten; die Kriterien einer Berufskrankheit nach Nr. 5101 der Anlage zur Berufskrankheitenverordnung sind erfüllt. Wir berichten über eine Floristin, die über 27 Jahre unter chronisch rezidivierenden, schließlich kontinuierlichen Ekzemen an den luftexponierten Hautpartien litt. Trotz Nachweis einer hochgradigen Spättypsensibilisierung gegenüber Kompositen ließ sich der aerogene Auslösemechanismus erst nach Tätigkeitsaufgabe mit Wegfall der ständigen Allergenexposition erkennen. Es demaskierte sich ein vom Pollenflug der Korbblütler abhängiges Frühjahr-Sommer-Herbst-Ekzem. Wegen der sehr ungünstigen Prognose durch Nichtvermeidbarkeit des Kontakts zu luftübertragenen Korbblütengewächsbestandteilen wird eine das herkömmliche Maß überschreitende Minderung der Erwerbsfähigkeit auf dem allgemeinen Arbeitsmarkt von 40 v. H. vorgeschlagen.

Published
2024
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13. MdE-Einschätzung nach Wegfall des Unterlassungszwangs – zur Diskussion gestellt

Author

Krohn, S., primary, Skudlik, C., additional, Bauer, A., additional, Bernhard-Klimt, C., additional, Dickel, H., additional, Drexler, H., additional, Elsner, P., additional, Engel, D., additional, Fartasch, M., additional, Glaubitz, S., additional, Gauglitz, G., additional, Goergens, A., additional, Köllner, A., additional, Kämpf, D., additional, Klinkert, M., additional, Kublik, E., additional, Merk, H., additional, Müller, M., additional, Palsherm, K., additional, Römer, W., additional, Ulrich, C., additional, and Worm, M., additional

Published
2022
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14. S1-Leitlinie Kontaktekzem

Author

Dickel, H., primary, Bauer, A., additional, Brehler, R., additional, Mahler, V., additional, Merk, H.F., additional, Neustädter, I., additional, Strömer, K., additional, Werfel, T., additional, Worm, M., additional, and Geier, J., additional

Published
2022
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18. Bullous pemphigoid after SARS‐CoV‐2 vaccination: spike‐protein‐directed immunofluorescence confocal microscopy and T‐cell‐receptor studies

Author

Gambichler, T., primary, Hamdani, N., additional, Budde, H., additional, Sieme, M., additional, Skrygan, M., additional, Scholl, L., additional, Dickel, H., additional, Behle, B., additional, Ganjuur, N., additional, Scheel, C., additional, Abu Rached, N., additional, Ocker, L., additional, Stranzenbach, R., additional, Doerler, M., additional, Pfeiffer, L., additional, and Becker, J.C., additional

Published
2022
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25. Peanut���induced anaphylaxis in children and adolescents: Data from the European Anaphylaxis Registry

Author

Maris, Ioana, D��lle���Bierke, Sabine, Renaudin, Jean���Marie, Lange, Lars, Koehli, Alice, Spindler, Thomas, Hourihane, Jonathan, Scherer, Kathrin, Nemat, Katja, Kemen, C., Neust��dter, Irena, Vogelberg, Christian, Reese, Thomas, Yildiz, Ismail, Szepfalusi, Zsolt, Ott, Hagen, Straube, Helen, Papadopoulos, Nikolaos G., H��mmerling, Susanne, Staden, Ute, Polz, Michael, Mustakov, Tihomir, Cichocka���Jarosz, Ewa, Cocco, Renata, Fiocchi, Alessandro Giovanni, Fernandez���Rivas, Montserrat, Worm, Margitta, Gr��nhagen, J, Wittenberg, M, Beyer, K, Henschel, A, K��per, S, M��ser, A, Fuchs, T, Ru��ff, F, Wedi, B, Hansen, G, Buck, T, B��sselberg, J, Dr��gerdt, R, Pfeffer, L, Dickel, H, K��rner���Rettberg, C, Merk, H, Lehmann, S, Bauer, A, Nordwig, A, Zeil, S, Hannapp, C, Wagner, N, Rietschel, E, Hunzelmann, N, Huseynow, I, Treudler, R, Aurich, S, Prenzel, F, Klimek, L, Pfaar, O, Reider, N, Aberer, W, Varga, E, Bogatu, B, Schmid���Grendelmeier, P, Guggenheim, R, Riffelmann, F, Kreft, B, Kinaciyan, K, Hartl, L, Ebner, C, Horak, F, Brehler, R, Witte, J, Buss, M, Hompes, S, Bieber, T, Gernert, S, B��cheler, M, Rabe, U, Brosi, W, Nestoris, S, Hawranek, T, Lang, R, Bruns, R, Pf��hler, C, Eng, P, Schweitzer���Krantz, S, Meller, S, Rebmann, H, Fischer, J, Stichtenoth, G, Thies, S, Gerstlauer, M, Utz, P, Neust��dter, I, Klinge, J, Volkmuth, S, Plank���Habibi, S, Schilling, B, Kleinheinz, A, Br��ckner, A, Sch��kel, K, Manolaraki, I, Kowalski, M, Solarewicz���Madajek, K, Tscheiller, S, Seidenberg, J, Cardona, V, Garcia, B, Bilo, M, Caba��es Higuero, N, Vega Castro, A, Poziomkowska���G��sicka, I, B��sing, S, Virchow, C, Christoff, G, Jappe, U, M��ller, S, Kn��pfel, F, Correard, A���K, Rogala, B, Montoro, A, Brandes, A, Muraro, A, Zimmermann, N, Hernandez, D, Minale, P, Niederwimmer, J, Zahel, B, Dahdah, L, Arasi, S, Reissig, A, Eitelberger, F, Asero, R, Hermann, F, Zeidler, S, Pistauer, S, Gei��ler, M, Ensina, L, Plaza Martin, A, Meister, J, Stieglitz, S, Hamelmann, E, and Network For Online Registration Of Anaphylaxis (NORA)

Subjects
0301 basic medicine, Allergy, medicine.medical_specialty, Adolescent, Arachis, Epinephrine, Immunology, Peanut allergy, Peanut-induced anaphylaxis, paediatrics, 03 medical and health sciences, 0302 clinical medicine, Food allergy, Internal medicine, medicine, anaphylaxis, Humans, Immunology and Allergy, Peanut Hypersensitivity, In patient, Registries, Child, Asthma, food allergy, business.industry, food and beverages, medicine.disease, Comorbidity, 030104 developmental biology, 030228 respiratory system, business, Anaphylaxis, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
Abstract

Background Peanut allergy has a rising prevalence in high-income countries, affecting 0.5%-1.4% of children. This study aimed to better understand peanut anaphylaxis in comparison to anaphylaxis to other food triggers in European children and adolescents. Methods Data was sourced from the European Anaphylaxis Registry via an online questionnaire, after in-depth review of food-induced anaphylaxis cases in a tertiary paediatric allergy centre. Results 3514 cases of food anaphylaxis were reported between July 2007 - March 2018, 56% in patients younger than 18 years. Peanut anaphylaxis was recorded in 459 children and adolescents (85% of all peanut anaphylaxis cases). Previous reactions (42% vs. 38%; p = .001), asthma comorbidity (47% vs. 35%; p < .001), relevant cofactors (29% vs. 22%; p = .004) and biphasic reactions (10% vs. 4%; p = .001) were more commonly reported in peanut anaphylaxis. Most cases were labelled as severe anaphylaxis (Ring&Messmer grade III 65% vs. 56% and grade IV 1.1% vs. 0.9%; p = .001). Self-administration of intramuscular adrenaline was low (17% vs. 15%), professional adrenaline administration was higher in non-peanut food anaphylaxis (34% vs. 26%; p = .003). Hospitalization was higher for peanut anaphylaxis (67% vs. 54%; p = .004). Conclusions The European Anaphylaxis Registry data confirmed peanut as one of the major causes of severe, potentially life-threatening allergic reactions in European children, with some characteristic features e.g., presence of asthma comorbidity and increased rate of biphasic reactions. Usage of intramuscular adrenaline as first-line treatment is low and needs to be improved. The Registry, designed as the largest database on anaphylaxis, allows continuous assessment of this condition.

Published
2021
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26. Penicillin tolerance induction in pregnancy: Allergological statement on the recommendation of the current guideline on diagnosis and treatment of syphilis (AWMF register no. 059-002)

Author

Wedi, B., Aberer, W., Brockow, K., Dickel, H., Brehler, R., Jakob, T., Kreft, B., Mahler, V, Merk, H. F., Muelleneisen, N., Ott, H., Pfuetzner, W., Roeseler, S., Rueff, F., Sunderkoetter, C., Trautmann, A., Treudler, R., Worm, M., Wurpts, G., Wedi, B., Aberer, W., Brockow, K., Dickel, H., Brehler, R., Jakob, T., Kreft, B., Mahler, V, Merk, H. F., Muelleneisen, N., Ott, H., Pfuetzner, W., Roeseler, S., Rueff, F., Sunderkoetter, C., Trautmann, A., Treudler, R., Worm, M., and Wurpts, G.

Published
2021

27. Bild und Text in der 'Historia plantarum' von Conrad Gessner

Author

Dickel, Hans, Engl, Elisabeth, Rautenberg, Ursula, Dickel, H ( Hans ), Engl, E ( Elisabeth ), Rautenberg, U ( Ursula ), Nyffeler, Reto; https://orcid.org/0000-0002-9293-5967, Dickel, Hans, Engl, Elisabeth, Rautenberg, Ursula, Dickel, H ( Hans ), Engl, E ( Elisabeth ), Rautenberg, U ( Ursula ), and Nyffeler, Reto; https://orcid.org/0000-0002-9293-5967

Published
2021

28. The Berkeley-Illinois-Maryland-Association Millimeter Array

Author

Welch, W. J., Thornton, D. D., Plambeck, R. L., Wright, M. C. H., Lugten, J., Urry, L., Fleming, M., Hoffman, W., Hudson, J., Lum, W. T., Forster, J. R., Thatte, N., Zhang, X., Zivanovic, S., Snyder, L., Crutcher, R., Lo, K. Y., Wakker, B., Stupar, M., Sault, R., Miao, Y., Rao, R., Wan, K., Dickel, H. R., Blitz, L., Vogel, S. N., Mundy, L., Erickson, W., Tauben, P. J., Morgan, J., Helfer, T., Looney, L., de Gues, E., Grossman, A., Howe, J. E., Pound, M., and Regan, M.

Published
1996

31. Is benzyl alcohol a significant contact sensitizer?

Author

Geier, J., Ballmer‐Weber, B., Buhl, T., Rieker‐Schwienbacher, J., Mahler, V., Dickel, H., Schubert, S., Baron, Jens Malte, Grabbe, Jürgen, Siedlecki, Katharina, Strom, Kerstin, Hartmann, Karin, Worm, Margitta, Simon, Dagmar, Effendy, Isaak, Dickel, Heinrich, Fartasch, Manigé, Vieluf, Dieter, Beiteke, Ulrike, and Bauer, Andrea

Subjects
BENZYL alcohol, ALLERGENS, INFORMATION networks, RELIABILITY in engineering, TEST reliability
Abstract

Background: Benzyl alcohol is a widely used preservative, solvent and fragrance material. According to published data, it is a rare sensitizer in humans. Objectives: To identify characteristics and sensitization patterns of patients with positive patch test reactions to benzyl alcohol and to check the reliability of the patch test preparation benzyl alcohol 1% pet. Patients and Methods: Retrospective analysis of data from the Information Network of Departments of Dermatology (IVDK), 2010–2019. Results: Of 70 867 patients patch tested with benzyl alcohol 1% pet., 146 (0.21%) showed a positive reaction, most of them (89%) only weakly positive. The number of doubtful and irritant reactions significantly exceeded the number of positive reactions. Reproducibility of positive test reactions was low. Among benzyl alcohol‐positive patients, compared to benzyl alcohol‐negative patients, there were significantly more patients with leg dermatitis (17.8% vs. 8.6%), more patients aged 40 years or more (81.5% vs. 70.5%) and more patients who were tested because of a suspected intolerance reaction to topical medications (34.9% vs. 16.6%). Concomitant positive reactions were mainly seen to fragrances, preservatives and ointment bases. Conclusions: Sensitization to benzyl alcohol occurs very rarely, mainly in patients with stasis dermatitis. In view of our results, benzyl alcohol cannot be regarded as a significant contact allergen, and therefore marking it as skin sensitizer 1B and labelling it with H 317 is not helpful. [ABSTRACT FROM AUTHOR]

Published
2022
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33. Berufskrankheit Nr. 5101 – Kausalitätsgrundsätze mit Fallbeispielen

Author

Skudlik, C., primary, Krohn, S., additional, Bauer, A., additional, Bernhard-Klimt, C., additional, Dickel, H., additional, Drexler, H., additional, Elsner, P., additional, Engel, D., additional, Fartasch, M., additional, Glaubitz, S., additional, Gauglitz, G., additional, Goergens, A., additional, Köllner, A., additional, Kämpf, D., additional, Klinkert, M., additional, Kublik, E., additional, Merk, H., additional, Palsherm, M. Müller K., additional, Römer, W., additional, Ulrich, C., additional, and Worm, M., additional

Published
2021
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35. Penicillin-Toleranzinduktion in der Schwangerschaft: Allergologische Stellungnahme zur Empfehlung der aktuellen Leitlinie Diagnostik und Therapie der Syphilis (AWMF-Register-Nr. 059-002)

Author

Wedi, B., primary, Aberer, W., additional, Brockow, K., additional, Dickel, H., additional, Brehler, R., additional, Jakob, T., additional, Kreft, B., additional, Mahler, V., additional, Merk, H.F., additional, Mülleneisen, N., additional, Ott, H., additional, Pfützner, W., additional, Röseler, S., additional, Ruëff, F., additional, Sunderkötter, C., additional, Trautmann, A., additional, Treudler, R., additional, Worm, M., additional, and Wurpts, G., additional

Published
2021
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36. Berufskrankheit Nr. 5101 – Rechtsbegriff der schweren oder wiederholt rückfälligen Hautkrankheit

Author

Skudlik, C., primary, Krohn, S., additional, Bauer, A., additional, Bernhard-Klimt, C., additional, Dickel, H., additional, Drexler, H., additional, Elsner, P., additional, Engel, D., additional, Fartasch, M., additional, Glaubitz, S., additional, Gauglitz, G., additional, Goergens, A., additional, Köllner, A., additional, Kämpf, D., additional, Klinkert, M., additional, Kublik, E., additional, Merk, H., additional, Müller, M., additional, Palsherm, K., additional, Römer, W., additional, Ulrich, C., additional, and Worm, M., additional

Published
2021
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45. Beurteilung der Auswirkung einer arbeitsbedingten Allergie gegenüber Meerestieren bei der Minderung der Erwerbsfähigkeit im Rahmen der BK 5101

Author

Dickel, H., primary, Kuehn, A., additional, Dickel, B., additional, Bauer, A., additional, Becker, D., additional, Fartasch, M., additional, Häberle, M., additional, John, S.M., additional, Mahler, V., additional, Skudlik, C., additional, Weisshaar, E., additional, Werfel, T., additional, Geier, J., additional, and Diepgen†, T.L., additional

Published
2020
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47. Atopy patch testing with aeroallergens in a large clinical population of dermatitis patients in Germany and Switzerland, 2000‐2015: a retrospective multicentre study

Author

Dickel, H., primary, Kuhlmann, L., additional, Bauer, A., additional, Bircher, A.J., additional, Breuer, K., additional, Fuchs, T., additional, Grabbe, J., additional, Mahler, V., additional, Pföhler, C., additional, Przybilla, B., additional, Rieker‐Schwienbacher, J., additional, Schröder‐Kraft, C., additional, Simon, D., additional, Treudler, R., additional, Weisshaar, E., additional, Worm, M., additional, Trinder, E., additional, and Geier, J., additional

Published
2020
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