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Your search keyword '"Diaz-Valle, D."' showing total 136 results
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136 results on '"Diaz-Valle, D."'

16. Detection of anti-SARS-CoV-2 antibodies in tears: Ocular surface immunity to COVID-19 Detección de anticuerpos anti-SARS-CoV-2 en lágrimas: inmunidad de la superficie ocular frente a COVID-19

Author

Guemes-Villahoz, N., Burgos-Blasco, B., Echevarria-Torres, P. L., Vidal-Villegas, B., Rodriguez de la Peña, A., Diaz-Valle, D., Fernández-Vigo, J. I., Sánchez-Ramón, S., Garcia-Feijoo, J., Guemes-Villahoz, N., Burgos-Blasco, B., Echevarria-Torres, P. L., Vidal-Villegas, B., Rodriguez de la Peña, A., Diaz-Valle, D., Fernández-Vigo, J. I., Sánchez-Ramón, S., and Garcia-Feijoo, J.

Abstract

Purpose: To evaluate the presence of SARS-CoV-2 specific IgA and IgG antibodies in tears of unvaccinated and anti-COVID-19 vaccinated subjects with previous history of SARS-CoV-2 infection. To compare results in tears with those in saliva and serum and correlate with clinical data and vaccination regimens. Methods: Cross-sectional study including subjects with a previous history of SARS-CoV-2 infection, both unvaccinated and vaccinated against COVID-19. Three samples were collected: tears, saliva and serum. IgA and IgG antibodies against S-1 protein of SARS-CoV-2 were analyzed with a semi-quantitative ELISA. Results: Thirty subjects, mean age 36.4 ± 10, males 13/30 (43.3%) with history of mild SARS-CoV-2 infection were included. 13/30 (43.3%) subjects had received a 2-dose regimen and 13/30 (43.3%) a 3-dose regimen of anti-COVID-19 vaccine, 4/30 (13.3%) subjects were unvaccinated. All the participants with full anti-COVID-19 vaccination (2-or 3-doses) presented detectable anti-S1 specific IgA in all 3 biofluids, tears, saliva and serum. Among unvaccinated subjects, specific IgA was detected in 3/4 subjects in tears and saliva, whereas IgG was not detected. Considering IgA and IgG antibodies titers, no differences were observed between the 2- and 3-dose vaccination regimen. Conclusions: SARS-CoV-2-specific IgA and IgG antibodies were detected in tears after mild COVID-19, highlighting the role of the ocular surface as a first line of defense against infection. Most naturally infected unvaccinated individuals exhibit long-term specific IgA in tears and saliva. Hybrid immunization (natural infection plus vaccination) appears to enhance mucosal and systemic IgG responses. However, no differences were observed between the 2- and 3-dose vaccination schedule.

Published
2023

36. Simulation in ophthalmology

Author

Muñoz-Hernández, A.M., García-Catalán, R., Santos-Bueso, E., López-Abad, C., Gil-De-Bernabé, J.G., Díaz-Valle, D., Benítez-Del-Castillo-Sánchez, J.M., and García-Sánchez, J.

Published
2011
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40. COMPARATIVE STUDY ON ANTI-TNF VS TOCILIZUMAB FOR TREATMENT OF REFRACTORY UVEITIC CYSTOID MACULAR EDEMA DUE TO BEHCET'S DISEASE. MULTICENTER STUDY OF 49 PATIENTS

Author

Atienza-Mateo B, Ferraz-Amaro I, Catalan E, Adan A, Garfella M, Martinez-Costa L, Coma M, Diaz-Llopis M, Herreras J, Blanco A, Torre I, Diaz-Valle D, Atanes-Sandoval A, Hernandez F, Insua S, Sanchez J, Almodovar R, Ruiz-Moreno O, Martinez M, Nolla J, Martin-Varillas J, Calvo-Rio V, Prieto-Pena D, Gonzalez-Gay M, and Blanco R

Published
2021

42. Endogenous endophthalmitis as initial manifestation of invasive pneumococcal disease

Author

Noemi Güemes-Villahoz, Chocrón Benbunan C, Donate-López J, Diaz-Valle D, Romero Paternina Ar, and María José Núñez-Orantos

Subjects
Microbiology (medical), Pharmacology, Endophthalmitis, Pneumococcal disease, business.industry, Endogenous endophthalmitis, General Medicine, Pneumococcal Infections, Pneumococcal Vaccines, Pneumococcal vaccine, Immunology, Carta al Director, Humans, Medicine, business
Published
2021

44. Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis: Fundamentals Of Care for UveitiS (FOCUS) Initiative

Author

Dick, A. D., Rosenbaum, J. T., Al-Dhibi, H. A., Belfort, R., Brezin, A. P., Chee, S. P., Davis, J. L., Ramanan, A. V., Sonoda, K. -H., Carreno, E., Nascimento, H., Salah, S., Salek, S., Siak, J., Steeples, L., Accorinti, M., Acharya, N., Adan, A., Agrawal, R., Akkoc, N., Al Ghamdi, S., Al Ghamdi, T., Al Saati, A., Alsabaani, N., Al-Shamarani, M., Bachta, A., Barisani-Asenbauer, T., Beare, N., Porto, F. B. O., Blanco, R., Yee, A. C. S., Chandran, V., Chiquet, C., Chng, H. H., Cimbalas, A., Cimino, L., Cordero-Coma, M., Cristobal, C., Cuevas, M., Eurico da Fonseca, J., de Boer, J., de la Torre, A., De Schryver, I., Derzko-Dzulynsky, L., Diaz-Valle, D., Merino, C. E. D., Facsko, A., Figueira, L., Fonollosa, A., Fortin, E., Gale, R., Galeazzi, M., Garcia, S., Garcia Ruiz de Morales, J. M., Gaspersic, N., Goldstein, D., Guedes, M., Guex-Crosier, Y., Gul, A., Hamam, R., Haroon, M., Hasegawa, K., Heiligenhaus, A., Hooper, C., Hwang, Y. -S., Hwang, D. -K., Juanola, X., Kaburaki, T., Kadayifcilar, S., Kempen, J., Kezuka, T., Kherani, A., Kirsimae, M., Kotaniemi, K., Kraut, A., Kubicka-Trzaska, A., Kuffova, L., Lightman, S., Lim, L., Lim, W. K., Mccluskey, P., Mcguire, M., Mirabelli, P., Miserocchi, E., Misiuk-Hojlo, M., Muccioli, C., Munoz, S., Murphy, C., Murray, P., Nagy, Z., Namba, K., Neri, P., Nguyen, Q., O'Gradaigh, D., Omair, M., Otsa, K., Ozyazgan, Y., Pablo, F., Paroli, M. P., Pleyer, U., Poor, G., Proenca, R., Rabinovitch, T., Read, R., Rebrov, M., Recillas-Gispert, C., Rothova, A., Schwartzman, S., Seve, P., Sharma, S., Sims, J., Sohar, N., Suhler, E., Szanto, S., Szepessy, Z., Tappeiner, C., Thorne, J., Tugal Tutkun, I., Turno-Krecicka, A., Van Calster, J., van der Horst-Bruinsma, I., Vidovic Valentincic, N., Vitale, A., Voorduin Ramos, S., Vukojevic, N., Wakefield, D., Willermain, F., Yalcindag, N., Yamamoto, J. H., Yeh, S., Zemaitiene, R., and Ziouzina, O.

Published
2018

47. Human tear metabolome

Author

Muñoz-Hernández, A.M., Galbis-Estrada, C., Santos-Bueso, E., Cuiña-Sardiña, R., Díaz-Valle, D., Gegúndez-Fernández, J.A., Pinazo-Durán, M.D., and Benítez-del-Castillo, J.M.

Published
2016
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48. Metabolómica de la lágrima

Author

Muñoz-Hernández, A.M., Galbis-Estrada, C., Santos-Bueso, E., Cuiña-Sardiña, R., Díaz-Valle, D., Gegúndez-Fernández, J.A., Pinazo-Durán, M.D., and Benítez-del-Castillo, J.M.

Published
2016
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