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The objective of this study was to evaluate if the use of quaternary ammonium associated with the fermentation cause synergism in control of oocysts of poultry litter. The poultrylitter recycled went through fermentation and/or disinfection with quaternary ammonium in sanitary interval between two successive housings of 160 chickens each. In the first housing, the birdswere inoculated orally with 3x103 Eimeria acervulina oocystsat 12 days old. With the removal of these birds, the housing area was divided into four pens of 5m2 each. Each pen represents atreatment group of the litter: group 1: untreated (control), group2: fermentation, group 3: disinfection and group 4: disinfection and fermentation. It was counted oocysts per gram of faeces(OOPG), determination of pre patent, intestinal lesions score,weight gain and feed conversion. The results showed no reductionin the number of oocysts recoveredfrom the single litter only (G3:2.26x1o6) in relation to untread litter (Gl: 2.54x106). Groups in which the litter was fermented (G2 and G4) showed significant reduction of oocysts in the control group, however, the fermented and desinfected litter (G4: 0.76x106) showed no significant difference in reducing the number of oocysts compared to single fermented litter (G2: 0.67x106). It follows that the desinfection with quaternary ammonium associated to fermentacion of the litter does not potentiate the control of avian coccidiosis. [ABSTRACT FROM AUTHOR]